CARBOXYACETIC ACID (MALONIC ACID)

Carboxyacetic acid (Malonic Acid) is a dicarboxylic organic acid widely used as a chemical intermediate in pharmaceuticals, agrochemicals, polymers, coatings, flavors, and specialty synthesis.
Carboxyacetic acid (Malonic Acid) is valued for its high reactivity, active methylene group, and ability to undergo condensation, esterification, and decarboxylation reactions.
Carboxyacetic acid (Malonic Acid) is an important building block in the synthesis of barbiturates, vitamins, dyes, and biodegradable polymers.

CAS Number: 141-82-2
EC Number: 205-503-0
Molecular Formula: C₃H₄O₄
Molecular Weight: 104.06 g/mol

Synonyms: Carboxyacetic Acid, Malonic Acid, Propanedioic Acid, Methanedicarboxylic Acid, Dicarboxymethane, Malonic Acid Anhydrous, Malonic Acid Technical Grade, Carboxyacetic Acid, Malonic Acid, Propanedioic Acid, Propylenedicarboxylic Acid, Methanedicarboxylic Acid (common reference), Dicarboxymethane, Malonic Acid Free Acid, Malonic Acid Anhydrous, Malonic Acid Hydrated, Malonic Acid Crystalline, Malonic Acid Powder, Malonic Acid Granules, Malonic Acid Fine Powder, Malonic Acid High Purity, Pure Malonic Acid, Extra Pure Malonic Acid, Technical Grade Malonic Acid, Industrial Grade Malonic Acid, Pharmaceutical Grade Malonic Acid, Food Grade Malonic Acid, Reagent Grade Malonic Acid, Analytical Grade Malonic Acid, ACS Grade Malonic Acid, Malonic Acid Chemical Reagent, Malonic Acid Organic Acid, Aliphatic Dicarboxylic Acid Malonic, Short-Chain Dicarboxylic Acid, C3 Dicarboxylic Acid, Propane-1,3-dioic Acid, HOOC-CH₂-COOH, Malonic Acid Molecular Form, Malonic Acid Intermediate, Malonic Acid Chemical Intermediate, Malonic Acid Synthesis Intermediate, Malonic Acid Fine Chemical, Malonic Acid Specialty Chemical, Malonic Acid Raw Material, Malonic Acid Industrial Chemical, Malonic Acid Polymer Intermediate, Malonic Acid Plasticizer Intermediate, Malonic Acid Resin Intermediate, Malonic Acid Agrochemical Intermediate, Malonic Acid Pharmaceutical Intermediate, Malonic Acid Dye Intermediate, Malonic Acid Flavor Intermediate

APPLICATIONS

Carboxyacetic acid (Malonic Acid) is used as a chemical intermediate.
Carboxyacetic acid (Malonic Acid) participates in Knoevenagel and malonic ester synthesis reactions.
Carboxyacetic acid (Malonic Acid) enables carbon–carbon bond formation.

Carboxyacetic acid (Malonic Acid) is used in pharmaceutical manufacturing.
Carboxyacetic acid (Malonic Acid) serves as a precursor for barbiturates and sedatives.
Carboxyacetic acid (Malonic Acid) supports synthesis of active pharmaceutical ingredients.

Carboxyacetic acid (Malonic Acid) is applied in agrochemical synthesis.
Carboxyacetic acid (Malonic Acid) is used to produce herbicides and pesticides.
Carboxyacetic acid (Malonic Acid) contributes to crop protection formulations.

Carboxyacetic acid (Malonic Acid) is used in polymer and resin chemistry.
Carboxyacetic acid (Malonic Acid) acts as a monomer and chain extender.
Carboxyacetic acid (Malonic Acid) supports biodegradable polymer development.

Carboxyacetic acid (Malonic Acid) is used in coatings and adhesives.
Carboxyacetic acid (Malonic Acid) improves crosslinking and film performance.
Carboxyacetic acid (Malonic Acid) enhances chemical resistance of cured systems.

Carboxyacetic acid (Malonic Acid) is applied in flavor and fragrance synthesis.
Carboxyacetic acid (Malonic Acid) is used in ester production.
Carboxyacetic acid (Malonic Acid) contributes to aroma compound manufacturing.

Carboxyacetic acid (Malonic Acid) is used in analytical chemistry.
Carboxyacetic acid (Malonic Acid) serves as a reagent and reference compound.
Carboxyacetic acid (Malonic Acid) supports laboratory-scale synthesis.

Carboxyacetic Acid (Malonic Acid) is used as an intermediate in pharmaceutical synthesis.
Carboxyacetic Acid (Malonic Acid) participates in the production of barbiturates and sedatives.
Carboxyacetic Acid (Malonic Acid) supports synthesis of active pharmaceutical ingredients.

Carboxyacetic Acid (Malonic Acid) is used in agrochemical manufacturing.
Carboxyacetic Acid (Malonic Acid) acts as a precursor for herbicides and pesticides.
Carboxyacetic Acid (Malonic Acid) improves structural flexibility in agrochemical intermediates.

Carboxyacetic Acid (Malonic Acid) is used in polymer chemistry.
Carboxyacetic Acid (Malonic Acid) serves as a monomer for specialty polyesters.
Carboxyacetic Acid (Malonic Acid) enables controlled chain extension reactions.

Carboxyacetic Acid (Malonic Acid) is used in flavor and fragrance synthesis.
Carboxyacetic Acid (Malonic Acid) acts as a building block for ester production.
Carboxyacetic Acid (Malonic Acid) supports synthesis of fruity and floral aroma compounds.

Carboxyacetic Acid (Malonic Acid) is used in dye and pigment manufacturing.
Carboxyacetic Acid (Malonic Acid) participates in synthesis of organic colorants.
Carboxyacetic Acid (Malonic Acid) improves chromophore formation efficiency.

Carboxyacetic Acid (Malonic Acid) is used in laboratory research.
Carboxyacetic Acid (Malonic Acid) is employed in Knoevenagel condensation reactions.
Carboxyacetic Acid (Malonic Acid) supports carbon–carbon bond formation studies.

Carboxyacetic Acid (Malonic Acid) is used in electroplating additives.
Carboxyacetic Acid (Malonic Acid) functions as a complexing agent in metal baths.
Carboxyacetic Acid (Malonic Acid) improves metal ion stability during plating.

Carboxyacetic Acid (Malonic Acid) is used in food and beverage research.
Carboxyacetic Acid (Malonic Acid) acts as an acidity regulator in experimental formulations.
Carboxyacetic Acid (Malonic Acid) contributes mild sourness in controlled applications.

Carboxyacetic Acid (Malonic Acid) is used in cosmetic ingredient synthesis.
Carboxyacetic Acid (Malonic Acid) supports preparation of exfoliating actives.
Carboxyacetic Acid (Malonic Acid) contributes to alpha-hydroxy acid derivative production.

Carboxyacetic Acid (Malonic Acid) is used in corrosion inhibition research.
Carboxyacetic Acid (Malonic Acid) chelates metal ions on reactive surfaces.
Carboxyacetic Acid (Malonic Acid) improves performance of experimental inhibitor systems.

Carboxyacetic Acid (Malonic Acid) is used in analytical chemistry.
Carboxyacetic Acid (Malonic Acid) serves as a standard for titration studies.
Carboxyacetic Acid (Malonic Acid) supports buffer solution preparation.

Carboxyacetic Acid (Malonic Acid) is used in textile auxiliary synthesis.
Carboxyacetic Acid (Malonic Acid) participates in production of fiber treatment agents.
Carboxyacetic Acid (Malonic Acid) enhances fixation of finishing chemicals.

Carboxyacetic Acid (Malonic Acid) is used in specialty chemical production.
Carboxyacetic Acid (Malonic Acid) acts as a versatile C3 building block.
Carboxyacetic Acid (Malonic Acid) enables synthesis of substituted acetic acids.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of substituted malonates.
Carboxyacetic Acid (Malonic Acid) enables alkylation reactions in organic chemistry.

Carboxyacetic Acid (Malonic Acid) is used in pharmaceutical research laboratories.
Carboxyacetic Acid (Malonic Acid) supports development of new drug candidates.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of vitamin intermediates.
Carboxyacetic Acid (Malonic Acid) participates in preparation of vitamin B derivatives.

Carboxyacetic Acid (Malonic Acid) is used in production of heterocyclic compounds.
Carboxyacetic Acid (Malonic Acid) facilitates ring-closure reactions.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of barbituric acid derivatives.
Carboxyacetic Acid (Malonic Acid) improves yield of sedative intermediates.

Carboxyacetic Acid (Malonic Acid) is used in polymer crosslinking research.
Carboxyacetic Acid (Malonic Acid) introduces flexible linkages in polymer chains.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of corrosion inhibitors.
Carboxyacetic Acid (Malonic Acid) contributes chelating functionality to inhibitor molecules.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of plastic additives.
Carboxyacetic Acid (Malonic Acid) improves compatibility of stabilizer systems.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of surfactant intermediates.
Carboxyacetic Acid (Malonic Acid) enables formation of amphiphilic structures.

Carboxyacetic Acid (Malonic Acid) is used in laboratory-scale esterification reactions.
Carboxyacetic Acid (Malonic Acid) improves control of ester chain length.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of biodegradable polymers.
Carboxyacetic Acid (Malonic Acid) contributes to environmentally friendly polymer design.

Carboxyacetic Acid (Malonic Acid) is used in production of specialty solvents.
Carboxyacetic Acid (Malonic Acid) supports synthesis of oxygenated solvent molecules.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of pharmaceutical excipients.
Carboxyacetic Acid (Malonic Acid) improves functionality of buffering agents.

Carboxyacetic Acid (Malonic Acid) is used in food additive research.
Carboxyacetic Acid (Malonic Acid) assists in development of acidity regulators.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of antioxidant intermediates.
Carboxyacetic Acid (Malonic Acid) supports stabilization of reactive compounds.

Carboxyacetic Acid (Malonic Acid) is used in analytical method development.
Carboxyacetic Acid (Malonic Acid) serves as a reference compound in chromatography.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of textile auxiliaries.
Carboxyacetic Acid (Malonic Acid) improves binding of functional finishes.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of specialty esters.
Carboxyacetic Acid (Malonic Acid) enables controlled branching in ester molecules.

Carboxyacetic Acid (Malonic Acid) is used in production of laboratory reagents.
Carboxyacetic Acid (Malonic Acid) supports preparation of teaching and research chemicals.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of UV-absorbing compounds.
Carboxyacetic Acid (Malonic Acid) contributes to stabilization of light-sensitive materials.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of electrochemical additives.
Carboxyacetic Acid (Malonic Acid) enhances ion interaction in experimental systems.

Carboxyacetic Acid (Malonic Acid) is used in synthesis of fine chemicals.
Carboxyacetic Acid (Malonic Acid) provides a versatile backbone for molecular modification.

DESCRIPTION

Carboxyacetic acid (Malonic Acid) is a white, crystalline solid with a mild acidic odor.
Carboxyacetic acid (Malonic Acid) contains two carboxyl groups attached to a central methylene group.
Carboxyacetic acid (Malonic Acid) exhibits high chemical reactivity due to its activated methylene position.

Carboxyacetic acid (Malonic Acid) readily undergoes esterification with alcohols.
Carboxyacetic acid (Malonic Acid) forms malonate esters used in organic synthesis.
Carboxyacetic acid (Malonic Acid) easily decarboxylates upon heating.

Carboxyacetic acid (Malonic Acid) is soluble in water and polar solvents.
Carboxyacetic acid (Malonic Acid) forms clear acidic solutions.
Carboxyacetic acid (Malonic Acid) is incompatible with strong oxidizers and bases.

Carboxyacetic acid (Malonic Acid) is stable under dry, cool conditions.
Carboxyacetic acid (Malonic Acid) decomposes upon prolonged heating.
Carboxyacetic acid (Malonic Acid) should be protected from moisture during storage.

Carboxyacetic Acid (Malonic Acid) is a dicarboxylic acid with the molecular formula C₃H₄O₄.
Carboxyacetic Acid (Malonic Acid) appears as a white crystalline solid at room temperature.
Carboxyacetic Acid (Malonic Acid) is odorless and has a mildly sour taste.

Carboxyacetic Acid (Malonic Acid) is highly soluble in water and polar solvents.
Carboxyacetic Acid (Malonic Acid) contains two carboxyl functional groups.
Carboxyacetic Acid (Malonic Acid) exhibits strong acidity compared to acetic acid.

Carboxyacetic Acid (Malonic Acid) readily undergoes decarboxylation when heated.
Carboxyacetic Acid (Malonic Acid) is widely used as a building block in organic synthesis.
Carboxyacetic Acid (Malonic Acid) supports carbon–carbon bond formation reactions.

Carboxyacetic Acid (Malonic Acid) shows good reactivity in esterification processes.
Carboxyacetic Acid (Malonic Acid) forms stable salts with alkali metals.
Carboxyacetic Acid (Malonic Acid) is compatible with many reaction catalysts.

Carboxyacetic Acid (Malonic Acid) should be stored in a cool, dry environment.
Carboxyacetic Acid (Malonic Acid) must be handled using standard chemical safety precautions.
Carboxyacetic Acid (Malonic Acid) is valued for its versatility, reactivity, and importance in synthetic chemistry.

PROPERTIES

Chemical Formula: C₃H₄O₄
Molecular Weight: 104.06 g/mol
Appearance: White crystalline powder
Odor: Slight acidic odor
Density: ~1.62 g/cm³ at 20°C
Melting Point: 134–136°C
Boiling Point: Decomposes before boiling
Solubility in Water: ~140 g/L at 20°C
Solubility in Alcohol: Soluble in ethanol and methanol
pKa₁: ~2.83
pKa₂: ~5.69
pH (1% solution): ~2.5–3.0
Thermal Stability: Decomposes above melting point with CO₂ release
Hygroscopicity: Slightly hygroscopic
Reactivity: Reacts with alcohols, bases, and amines
Storage Temperature: Store below 25°C in dry conditions
Partition Coefficient (log P): −0.2 (estimated)

FIRST AID

Inhalation:
Move to fresh air immediately.
Seek medical attention if irritation persists.

Skin Contact:
Wash skin with plenty of water.
Remove contaminated clothing.

Eye Contact:
Rinse eyes with water for at least 15 minutes.
Seek medical attention if irritation continues.

Ingestion:
Rinse mouth and drink water.
Seek medical advice if discomfort occurs.

Note to Physicians:
Treat symptomatically for mild organic acid exposure.

HANDLING AND STORAGE

Handling:
Avoid dust formation.
Use gloves, goggles, and protective clothing.
Ensure adequate ventilation during handling.

Avoidance:
Avoid strong oxidizing agents and strong bases.
Avoid excessive heat and moisture exposure.

Spill Procedures:
Sweep up carefully and avoid dust generation.
Dispose of waste according to local regulations.

Storage:
Store in tightly closed containers.
Keep in a cool, dry, well-ventilated place.
Protect from moisture and heat sources.