CERAMIDE 6 II

Ceramide 6 II is a synthetic skin-identical ceramide, chemically known as ceramide 6 (ceramide VI) and widely used in dermatological and cosmetic formulations.
Ceramide 6 II plays an essential role in repairing the skin barrier, maintaining hydration, and supporting skin elasticity.
It is particularly effective in soothing sensitive and dry skin, reducing roughness, and improving skin smoothness.
Ceramide 6 II is incorporated into high-performance skincare, haircare, and pharmaceutical products designed for barrier repair and moisturization.

CAS Number: 100403-19-8
EC Number: Not assigned
Molecular Formula: C34H67NO5 (approximate, depending on structural variant)
Molecular Weight: ~553–565 g/mol (formulation dependent)

Synonyms: Ceramide 6 II, N-Stearoyl-6-hydroxysphingosine, Ceramide VI, Synthetic Ceramide 6 II, Skin-identical Ceramide 6 II, Ceramide 6 II Cosmetic Grade, Ceramide 6 II Hydrating Agent, Ceramide 6 II Skin Lipid, Ceramide 6 II Moisturizer, Ceramide 6 II Barrier Repair Agent, Ceramide 6 II Active, Ceramide 6 II Emollient, Ceramide 6 II, Ceramide VI, α-Hydroxy-N-stearoylphytosphingosine, Alpha-Hydroxy-N-stearoylphytosphingosine, α-Hydroxyceramide, Alpha Hydroxy Ceramide, Hydroxylated Ceramide, Ceramide AP, Ceramide 6II, Ceramide VI Type II, Ceramide 6-II, Ceramide 6 Second Type, Ceramide 6 Category II, Ceramide 6 Subtype II, Ceramide 6 Variant II, Ceramide 6 Form II, Ceramide 6 Isoform II, Ceramide 6 Derivative II, Ceramide 6 II Lipid, Ceramide 6 II Molecule, Ceramide 6 II Compound, Ceramide 6 II Material, Ceramide 6 II Substance, Ceramide 6 II Chemical, Ceramide 6 II Solid, Ceramide 6 II Powder, Ceramide 6 II Crystals, Ceramide 6 II Granules, Ceramide 6 II Pure, Ceramide 6 II High Purity, Ceramide 6 II Extra Pure, Ceramide 6 II Refined, Ceramide 6 II Stabilized, Ceramide 6 II Certified, Ceramide 6 II Analytical Standard, Ceramide 6 II Certified Standard, Ceramide 6 II Laboratory Standard

APPLICATIONS

Ceramide 6 II is used in moisturizers for dry and sensitive skin to restore barrier function.
Ceramide 6 II improves hydration levels and enhances skin smoothness.
Ceramide 6 II reduces flakiness and roughness in daily skincare products.

Ceramide 6 II is applied in anti-aging creams and serums for barrier support.
Ceramide 6 II helps reduce fine lines caused by dehydration.
Ceramide 6 II improves elasticity and suppleness of aging skin.

Ceramide 6 II is incorporated into dermatological formulations for eczema and psoriasis.
Ceramide 6 II reduces irritation and supports barrier repair in compromised skin.
Ceramide 6 II enhances therapeutic efficacy of medicated topical products.

Ceramide 6 II is used in sunscreens to strengthen skin protection.
Ceramide 6 II helps reduce UV-induced dehydration and irritation.
Ceramide 6 II contributes to photoprotection by reinforcing the barrier.

Ceramide 6 II is included in lip balms and treatments for dryness.
Ceramide 6 II enhances smoothness and hydration of lips.
Ceramide 6 II provides long-lasting moisture in protective lip formulations.

Ceramide 6 II is applied in haircare formulations, including shampoos and conditioners.
Ceramide 6 II restores damaged hair fibers and reduces breakage.
Ceramide 6 II improves shine, softness, and hair manageability.

Ceramide 6 II is used in scalp treatments for hydration and barrier reinforcement.
Ceramide 6 II helps reduce dandruff and irritation.
Ceramide 6 II supports healthy scalp microbiome balance.

Ceramide 6 II is applied in wound-healing and repair creams.
Ceramide 6 II accelerates skin regeneration in damaged areas.
Ceramide 6 II reduces transepidermal water loss (TEWL) during healing.

Ceramide 6 II is formulated into baby care products for delicate skin.
Ceramide 6 II strengthens the barrier in infant skincare formulations.
Ceramide 6 II reduces external irritant sensitivity in baby lotions.

Ceramide 6 II is incorporated into pharmaceutical creams as an excipient.
Ceramide 6 II enhances the absorption of therapeutic agents in skin.
Ceramide 6 II provides moisturizing and protective effects in medicated creams.

Ceramide 6 II is used in moisturizers.
Ceramide 6 II restores hydration in dry and sensitive skin.
Ceramide 6 II prevents transepidermal water loss.

Ceramide 6 II is applied in anti-aging creams.
Ceramide 6 II reduces the appearance of fine lines.
Ceramide 6 II improves elasticity and firmness of skin.

Ceramide 6 II is used in serums.
Ceramide 6 II enhances delivery of actives into the skin barrier.
Ceramide 6 II provides long-lasting skin conditioning effects.

Ceramide 6 II is incorporated in sunscreens.
Ceramide 6 II strengthens the skin barrier against UV exposure.
Ceramide 6 II reduces oxidative stress caused by sunlight.

Ceramide 6 II is used in facial cleansers.
Ceramide 6 II provides gentle cleansing with barrier repair.
Ceramide 6 II leaves skin soft and smooth after washing.

Ceramide 6 II is applied in eye creams.
Ceramide 6 II reduces puffiness and dryness around the eyes.
Ceramide 6 II enhances hydration for delicate eye-area skin.

Ceramide 6 II is incorporated in lip care products.
Ceramide 6 II helps repair cracked and chapped lips.
Ceramide 6 II improves softness in lip balms and treatments.

Ceramide 6 II is used in body lotions.
Ceramide 6 II enhances smoothness of rough and flaky skin.
Ceramide 6 II improves resilience of the skin barrier.

Ceramide 6 II is applied in hair care products.
Ceramide 6 II strengthens the cuticle layer of hair.
Ceramide 6 II improves smoothness and shine in conditioners.

Ceramide 6 II is incorporated in baby care products.
Ceramide 6 II provides protective barrier support for sensitive skin.
Ceramide 6 II reduces irritation in infant skincare.

Ceramide 6 II is used in dermatological treatments.
Ceramide 6 II supports therapies for eczema and psoriasis.
Ceramide 6 II helps repair compromised skin barriers.

Ceramide 6 II is applied in wound-healing formulations.
Ceramide 6 II aids in tissue regeneration.
Ceramide 6 II accelerates healing of minor skin injuries.

DESCRIPTION

Ceramide 6 II appears as a lipidic substance in cosmetic formulations.
Ceramide 6 II is insoluble in water but dispersible in emulsions.
Ceramide 6 II is soluble in oils and compatible with surfactants.

Ceramide 6 II supports the natural lipid matrix of skin.
Ceramide 6 II provides long-lasting moisturization.
Ceramide 6 II improves barrier resistance against environmental stress.

Ceramide 6 II is stable in cosmetic formulation ranges.
Ceramide 6 II is safe for use in personal care and dermatological products.
Ceramide 6 II is considered well-tolerated even in sensitive skin types.

Ceramide 6 II is biodegradable and naturally present in the human body.
Ceramide 6 II supports repair of damaged or aged skin.
Ceramide 6 II is regarded as a premium functional ingredient in skincare.

Ceramide 6 II is a synthetic lipid designed to mimic natural ceramides present in the stratum corneum.
It appears as a white to off-white powder or waxy solid.
Ceramide 6 II is insoluble in water but soluble in oils, ethanol, and emulsifiers.

Ceramide 6 II is biocompatible and well tolerated on sensitive or damaged skin.
It is chemically stable under cosmetic formulation conditions.

Ceramide 6 II shows synergistic effects with other ceramides, cholesterol, and fatty acids.
Ceramide 6 II plays a key role in advanced cosmetic and dermatological science for hydration and skin repair.

PROPERTIES

Appearance: White to off-white powder or waxy solid
Odor: Odorless or faint characteristic
Density: Not determined (lipid-based solid)
Melting Point: Approx. 90–100°C
Solubility: Insoluble in water; soluble in oils, ethanol, and emulsifiers
pH (in emulsions): Neutral
Chemical Nature: Synthetic ceramide lipid
Reactivity: Stable under normal storage and handling conditions
Storage Temperature: Store at 15–30°C in sealed containers, protected from light and moisture

FIRST AID

Inhalation:
Not hazardous under normal use.
Move to fresh air if dust is inhaled.

Skin Contact:
Rinse with water if irritation occurs.
Generally non-irritating and safe for topical use.

Eye Contact:
Flush with water if particles enter the eye.
Seek medical advice if irritation persists.

Ingestion:
Not intended for ingestion.
Rinse mouth with water if swallowed.

Note to Physicians:
Treat symptomatically.
No specific antidote required.

HANDLING AND STORAGE

Handling:
Wear protective gloves and eyewear when handling powders.
Avoid generating dust during processing.

Ventilation:
Ensure good ventilation during handling in powdered form.

Avoidance:
Do not mix with strong oxidizing agents.
Prevent contamination with moisture.

Spill and Leak Procedures:
Sweep up spilled material mechanically.
Dispose of waste according to local regulations.

Storage:
Store in a cool, dry, sealed container.
Protect from excessive heat, light, and humidity.