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Ceramide complex acts as an anti-wrinkle- and skin-barrier restoring agent.
Ceramide complex is a vegetable-derived lipid concentrate consisting of a multi-lamellar system that resembles the structure of the lipid barrier of skin.
Ceramide complex contains semi-synthetic cholesterol and ceramides & phytosphingosines, extracted from vegetable sources & microorganisms.
CAS Number: 497156-25-9
Molecular Formula: C22H45NO2
Molecular Weight: 355.6
Synonyms: N-BUTYL-D-SPHINGOSINE;N-BUTYROYL-D-ERYTHRO-SPHINGOSINE;04:0 CERAMIDE;BUTYL CERAMIDE;C4 CERAMIDE
Ceramide complex is an innovative blend of Ceramide NP, Ceramide AP, Phytosphingosine, and cholesterol that work together to reinforce the skin's natural barrier function, enhance hydration, and offer comprehensive protection, resulting in a smoother and healthier appearance.
Compared to individual ceramides, Ceramide complex can be integrated into formulations, featuring finer and more uniform particles that ensure improved stability without any precipitation concerns.
Ceramide complex refers to a blend of different types of ceramides, which are lipid molecules naturally found in the skin’s outermost layer (stratum corneum).
These lipids play a crucial role in maintaining the skin barrier, retaining moisture, and protecting against environmental stressors such as pollutants, allergens, and bacteria.
A Ceramide Complex is often formulated with a combination of various ceramide types, along with other skin-nourishing ingredients like cholesterol, fatty acids, and phytosphingosine, to enhance skin health, hydration, and barrier function.
Ceramides make up approximately 50% of the skin's lipid barrier, and their presence is essential for maintaining skin elasticity, smoothness, and resilience.
However, factors such as aging, harsh skincare products, environmental damage, and skin conditions (like eczema and psoriasis) can lead to a decline in ceramide levels, resulting in dryness, irritation, and increased sensitivity.
Ceramide Complex formulations are designed to replenish these essential lipids, helping to restore and strengthen the skin’s natural defense mechanisms.
Ceramide complex is a specialized skincare ingredient composed of a blend of different types of ceramides, which are naturally occurring lipid molecules found in the outermost layer of the skin (stratum corneum).
These ceramides serve as structural components of the skin’s protective barrier, helping to retain moisture, prevent dehydration, and defend against external aggressors such as pollution, harsh weather, and bacteria.
Ceramide complex helps to improve the appearance of aged skin by deep moisturizing effects and restores the protective barrier function of the skin.
It promotes enhanced delivery and exchange of skin lipids (ceramides).
It is preserved with phenoxyethanol and ethylhexylglycerin.
Ceramide complex is used in anti-aging- & anti-wrinkle creams, lotions, creams for sensitive & dry skin, sun care and after sun products.
It is vegan and GMO-free.
The shelf life is 24 months from production date.
Ceramide Complex is a multi-lamellar system of vegetable-derived, semi-synthetic ceramides, cholesterol, free fatty acids and phytosphingosine.
Identical to lipids found in the skin, it has been concentrated and formulated into a system to provide enhanced skin moisturization and protection.
Ceramide Complex restores the protective barrier function of the skin and offers enhanced delivery and exchange of skin lipids.
Ceramide Complex is especially suitable for dry skin, aging skin and sensitive skin.
In healthy skin, ceramides make up nearly 50% of the intercellular lipids in the epidermis, forming a protective matrix that holds skin cells together like mortar in a brick wall.
However, due to aging, environmental damage, excessive cleansing, and harsh skincare treatments, ceramide levels can become depleted.
When this happens, the skin barrier weakens, leading to increased water loss (transepidermal water loss or TEWL), dryness, irritation, and heightened sensitivity.
A Ceramide Complex is specifically designed to replenish these lost lipids, restoring the skin’s natural barrier function, improving hydration, reducing irritation, and enhancing overall resilience.
This complex is typically formulated with a combination of different ceramide types, alongside other skin-repairing ingredients such as cholesterol, free fatty acids, and phytosphingosine, which work synergistically to strengthen and maintain healthy skin.
Ceramide complex is an innovative blend of Ceramide NP, Ceramide AP, Phytosphingosine, and cholesterol that work together to reinforce the skin's natural barrier function, enhance hydration, and offer comprehensive protection, resulting in a smoother and healthier appearance.
Compared to individual ceramides, Ceramide complex can be integrated into formulations, featuring finer and more uniform particles that ensure improved stability without any precipitation concerns.
Ceramide complex is a multi-lamellar system of vegetable-derived, semi-synthetic ceramides, cholesterol, free fatty acids and phytosphingosine.
Identical to lipids found in the skin, it has been concentrated and formulated into a system to provide enhanced skin moisturization and protection.
In addition to ceramides, cholesterol and free fatty acids are often included in Ceramide Complex formulations to enhance absorption and functionality, ensuring optimal restoration of the skin barrier.
The primary function of ceramides is to act as the "glue" that holds skin cells together, forming a protective shield against external aggressors.
A damaged skin barrier can lead to redness, irritation, and increased sensitivity, which Ceramide Complex helps to repair and reinforce.
Ceramides help the skin retain water by preventing transepidermal water loss (TEWL), keeping the skin plump and hydrated.
Many moisturizers, serums, and creams enriched with Ceramide Complex are recommended for individuals experiencing dry, flaky, or dehydrated skin.
Ceramide complex is a highly beneficial skincare ingredient that restores the skin barrier, retains moisture, reduces signs of aging, and soothes irritation.
Ceramide complex is especially valuable for those with dry, sensitive, or damaged skin, as well as individuals looking to maintain a healthy, resilient complexion. Whether in moisturizers, serums, or cleansers, incorporating ceramides into a daily skincare routine can significantly improve skin hydration, elasticity, and overall skin health over time.
One of the most crucial functions of ceramides is to act as the "glue" that binds skin cells together, forming a protective shield against environmental stressors, such as pollution, bacteria, UV radiation, and harsh weather conditions.
When the skin’s lipid barrier is damaged, it becomes more vulnerable to irritation, redness, and inflammation, making it more prone to sensitivity and skin disorders.
Using a Ceramide Complex helps to reinforce the skin barrier, restoring strength, resilience, and protection.
Ceramides play a vital role in preventing excessive water loss from the skin by sealing in hydration, ensuring the skin remains plump, smooth, and well-moisturized.
Ceramide complex is a common cause of dryness, flakiness, and rough texture, and ceramides help to significantly reduce this moisture loss.
This makes ceramide-based products particularly beneficial for individuals who experience chronic dryness, dehydration, or rough patches on their skin.
As the skin ages, the natural production of ceramides declines, leading to increased dryness, fine lines, sagging, and a weakened skin barrier.
By incorporating a Ceramide complex into a daily skincare routine, individuals can restore lost lipids, improving skin firmness, elasticity, and hydration while reducing the appearance of wrinkles and fine lines.
Since ceramides also support collagen production, they contribute to firmer, younger-looking skin over time.
Exposure to pollution, UV rays, and harsh environmental conditions can degrade skin lipids, making the skin more prone to oxidative stress, inflammation, and premature aging.
Ceramides create a defensive layer that helps to protect against toxins, free radicals, and environmental pollutants, keeping the skin healthier and more resilient.
Melting point: 64-67°C
Storage temp.: -20°C Freezer
Solubility: Chloroform (Slightly), Methanol (Slightly)
Form: Solid, Powder
Color: Off-White
UNSPSC Code: 12352211
NACRES: NA.25
Ceramides are signaling molecules which play a key role in cellular events.
Ceramides promote β-amyloid synthesis and induce neuronal death.
Ceramide levels are associated with pathogenesis of many disease states.
Impairment of ceramide metabolism is implicated in Parkinsonμs and Alzheimerμs disease.
High levels of ceramide is also associated with depression.
Ceramide complex acts as a moisturizing agent.
Ceramide complex contains 2% lipids in lamellar, liquid crystalline form.
The plant-derived lipid mixture consists of at least 10% sphingolipids (ceramides, glycoceramides = cerebrosides).
Ceramide complex restores the lipid barrier of dry & fissured skin and provides a well balanced moisture content.
Ceramide Complex CLR™ K is miscible with water, but not clearly water-soluble.
Ceramide complex is used in aqueous and emulsified skin care preparations, especially gels.
Ceramide complex has a shelf life of 1 year.
Ceramide Complex is a skin-identical, synergistic lipid concentrate for improved skin moisturisation and protection by restoring the protective function of the skin and scalp.
Easy to use and effective in action.
Ceramide Complex is a Skin-identical synergistic lipid concentrate for enhanced skin moisturization and protection through restoring the protective function of skin and scalp.
A concentrated mix of different types of ceramides, cholesterol, free fatty acids, and phytosphingosine makes it an ideal ingredient for personal care products with unique restoring capabilities.
A Ceramide Complex usually contains a carefully balanced blend of multiple ceramide types, each of which plays a specific role in maintaining skin health, hydration, and protection.
The most common ceramides used in skincare formulations include:
Ceramide complex – Essential for locking in moisture and improving skin elasticity by reinforcing the lipid bilayer structure that holds skin cells together.
Ceramide complex – Helps to restore and maintain skin hydration, preventing excessive moisture loss and keeping the skin supple.
Ceramide complex – Strengthens the skin’s natural barrier, making it more resilient against external irritants, allergens, and pollutants.
Ceramide complex – Has mild exfoliating properties, which help to smooth rough or flaky skin, making it beneficial for individuals with dry or aging skin.
Ceramide complex – Assists in rebuilding and repairing damaged skin barriers, particularly in individuals with conditions like eczema, psoriasis, or rosacea.
In addition to ceramides, cholesterol and free fatty acids are often included in Ceramide Complex formulations because these components are necessary for ceramides to function properly.
They form a balanced lipid mixture that mimics the natural composition of healthy skin, ensuring optimal absorption and effectiveness.
Many people with skin conditions such as eczema, psoriasis, rosacea, or dermatitis have significantly lower levels of ceramides, which contributes to inflammation, irritation, and a compromised skin barrier.
A Ceramide Complex helps to restore these essential lipids, reducing redness, sensitivity, and flare-ups while strengthening the skin against future irritants.
This makes ceramides ideal for people with reactive or allergy-prone skin, as they are naturally gentle, non-irritating, and well-tolerated by most individuals.
5. Repairing Skin Damage from Harsh Skincare Ingredients and Over-Exfoliation
Many people use harsh cleansers, exfoliating acids (AHAs, BHAs), or retinoids, which can strip the skin of its natural lipids, leading to dryness, peeling, or irritation.
Ceramide Complex formulations help to counteract these effects by replenishing lost lipids, restoring balance to the skin, and preventing damage caused by excessive exfoliation.
Ceramide Complex is found in a variety of skincare products, each designed to deliver hydration, repair, and protection in different ways.
Provide deep hydration and restore the skin barrier, making them ideal for dry, sensitive, and aging skin.
Lightweight, fast-absorbing formulas that penetrate deeply into the skin, offering long-lasting hydration and repair.
Gentle, non-stripping face washes that cleanse while maintaining essential skin lipids.
Target fine lines, puffiness, and dryness around the delicate eye area.
Some advanced sun protection products include ceramides to protect while reinforcing the skin barrier.
A Ceramide Complex is a highly effective skincare ingredient that strengthens the skin barrier, enhances hydration, prevents aging, and soothes irritation.
Whether used in moisturizers, serums, or cleansers, incorporating ceramides into a daily skincare routine can significantly improve skin health, resilience, and overall appearance over time.
Uses Of Ceramide complex:
Ceramide complex has been used as a lipid standard.
Ceramide complex in ultra performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry (UPLC-ESI-Q-TOF-MS).
In liquid chromatography with a hydrophilic interaction column.
In liposome preparation to test it effect on human α–synuclein aggregation.
Many individuals use exfoliating treatments, such as scrubs, acids, or retinol, to remove dead skin cells and improve skin texture.
However, over-exfoliation or using products that are too harsh can damage the skin’s natural barrier, leading to redness, dryness, and sensitivity.
Ceramide complex is highly effective in supporting the recovery process after such treatments.
Ceramide complex works to replenish lost lipids and restore the skin’s ability to hold onto moisture, helping to calm irritated skin and reduce peeling, ensuring that the skin remains healthy and protected after exfoliation.
A ceramide derivative for pharmaceutical use as antitumor agents.
While ceramides are often recommended for dry and sensitive skin, they are also beneficial for people with combination skin, which tends to experience both oily and dry patches.
By using a Ceramide Complex, individuals with combination skin can balance moisture levels, providing hydration to dry areas without exacerbating oiliness in other areas of the face.
Ceramides act to normalize skin hydration, helping to create an even, balanced complexion where dry patches are moisturized, and oily zones are less prone to dehydration and irritation.
This balance is key to maintaining skin health and stability.
It can be used add to aqueous phase of formulas.
May lower viscosity when added to existing o/w emulsions.
Ceramide complex store in refrigerator (shelf life about 6 months when refrigerated).
Ceramide Complex is widely utilized in a variety of skincare products, offering multiple benefits that target specific skin concerns.
Ceramide complexs versatile uses make it an essential component in skincare formulations designed to restore the skin barrier, enhance hydration, and repair damaged skin.
One of the primary functions of a Ceramide Complex is to reinforce the skin's natural barrier, which serves as the first line of defense against external irritants, pollutants, bacteria, and harmful environmental factors such as harsh weather conditions and UV radiation.
The skin’s outer layer (stratum corneum) relies on ceramides to maintain structural integrity by holding the skin cells together, effectively creating a protective shield.
When the barrier is compromised due to aging, environmental damage, or excessive cleansing, the skin becomes more prone to dryness, irritation, and inflammation.
Regular use of Ceramide Complex helps to restore the damaged barrier, making the skin more resilient and better equipped to resist environmental stressors.
This, in turn, promotes overall skin health and long-term protection.
Ceramides are vital for preventing moisture loss and maintaining the skin’s hydration levels.
The transepidermal water loss (TEWL) that occurs when ceramides are deficient can lead to skin that feels dry, tight, and rough.
A Ceramide Complex helps to seal in moisture by forming a lipid layer that prevents excessive water evaporation from the skin’s surface.
This is particularly beneficial for individuals with dry, flaky, or dehydrated skin, as it ensures that moisture is locked into the skin, leaving it feeling smooth, plump, and deeply hydrated. Using products enriched with Ceramide Complex provides continuous hydration, helping the skin maintain its natural moisture balance throughout the day.
Skin conditions such as eczema, psoriasis, rosacea, and dermatitis can result in a compromised skin barrier, leading to redness, irritation, and inflammation.
When ceramide levels are depleted or disrupted due to these conditions, the skin becomes vulnerable to further damage.
A Ceramide Complex formulation is specifically designed to repair and replenish the lipids that make up the skin barrier, helping to restore skin’s integrity and reduce irritation.
This makes Ceramide Complex an essential ingredient in healing and soothing sensitive skin, particularly for individuals prone to skin conditions that cause discomfort and inflammation.
As the skin ages, the natural production of ceramides declines, which can lead to dryness, sagging, and the formation of fine lines and wrinkles.
By restoring the lipid content in the skin, Ceramide Complex helps to plump and firm the skin, reducing the appearance of fine lines and wrinkles.
Ceramide complexs ability to strengthen the skin barrier also makes the skin appear more youthful and smooth.
In anti-aging skincare products, Ceramide Complex is commonly used to improve elasticity and firmness, ensuring that the skin remains hydrated, radiant, and more resilient as it ages.
Individuals with sensitive skin or those who experience allergic reactions to environmental triggers often suffer from redness, irritation, and inflammation.
A weakened skin barrier makes the skin more vulnerable to these effects.
Ceramide Complex is ideal for soothing irritated skin by replenishing lost ceramides and enhancing the skin’s ability to retain moisture.
As it helps to repair the skin barrier, it also reduces the skin’s sensitivity to external irritants and allergens, providing relief from discomfort and promoting a calm, balanced complexion.
This makes Ceramide Complex especially beneficial for individuals with eczema, rosacea, and other inflammatory skin conditions.
The skin is constantly exposed to environmental pollutants, UV radiation, and harsh weather conditions, all of which can degrade the lipid barrier and increase the skin’s susceptibility to free radicals and oxidative stress.
Ceramide Complex plays a crucial role in protecting the skin from these environmental aggressors by strengthening the skin’s natural defense mechanisms.
Ceramide complex not only helps to shield the skin from pollutants but also plays a part in defending against the damage caused by UV exposure.
By keeping the skin’s barrier intact and well-hydrated, Ceramide Complex helps reduce the risk of premature aging, skin irritation, and sun damage caused by environmental factors.
Ceramides help the skin retain its smooth texture by locking in hydration and maintaining the integrity of the skin barrier.
When the skin’s barrier is intact, it is less likely to experience roughness, flakiness, or uneven skin texture.
Regular use of products containing Ceramide Complex helps to smooth out rough patches, providing the skin with a soft, even, and supple texture.
This is especially beneficial for individuals with uneven skin texture, dry patches, or dehydrated skin, as the Ceramide Complex ensures that the skin remains well-moisturized and plump, promoting a youthful, healthy appearance.
After undergoing dermatological procedures such as chemical peels, laser treatments, or microneedling, the skin may be left irritated, dry, and sensitive.
Using a Ceramide Complex during the recovery phase can help accelerate healing by restoring moisture and reinforcing the skin’s protective barrier.
Ceramides aid in reducing redness, calming inflammation, and speeding up the skin’s natural repair process, making them an essential post-procedure treatment for maintaining skin integrity and preventing further damage.
Ceramide Complex is often used in conjunction with other active ingredients like retinoids, AHAs (alpha hydroxy acids), BHAs (beta hydroxy acids), and Vitamin C to enhance the overall effectiveness of a skincare routine.
For example, retinoids can sometimes cause skin irritation, dryness, and peeling, but combining them with Ceramide Complex helps to reduce these side effects by maintaining a hydrated, balanced skin barrier.
Similarly, AHAs and BHAs, which are commonly used for exfoliating the skin, can leave the skin feeling dry and vulnerable; ceramides work to nourish and replenish the skin, ensuring that the barrier remains intact while still benefiting from the exfoliating effects.
Ceramide Complex is an excellent addition to any daily skincare routine, providing ongoing hydration and protection throughout the day.
By supporting the skin’s natural barrier, ceramides help maintain optimal skin health and ensure that the skin remains well-moisturized, resilient, and protected from everyday environmental stressors.
Regular use of ceramide-infused products ensures that the skin remains hydrated and nourished, preventing it from becoming dry, irritated, or sensitized over time.
This makes Ceramide Complex an essential ingredient for maintaining healthy, glowing, and balanced skin on a long-term basis.
The uses of Ceramide Complex span a wide range of skincare benefits, from restoring the skin barrier and boosting hydration to soothing irritation and protecting against environmental damage.
By replenishing essential lipids that support the skin’s structure and barrier function, Ceramide Complex provides long-lasting relief for dry, sensitive, or aging skin.
Whether used to enhance the skin’s resilience or to accelerate healing after treatments, its ability to improve skin texture, moisture retention, and overall skin health makes it an indispensable ingredient in modern skincare.
Ceramides are known to work synergistically with other active skincare ingredients, enhancing their penetration and effectiveness.
For instance, in products containing retinol or vitamin C, ceramides help prevent irritation, which these potent actives can sometimes cause, by maintaining the skin’s barrier function and hydration levels.
They also calm any inflammation that may result from the use of potent exfoliants or brightening agents, making the overall skincare routine more tolerable for those with sensitive skin.
By supporting the skin’s natural defense system, Ceramide Complex helps these active ingredients perform more
Safety Profile Of Ceramide complex:
In rare cases, some individuals may experience allergic reactions or skin sensitivity to ceramide-based products.
Symptoms of an allergic reaction can include redness, itching, swelling, rash, or hives at the application site.
While ceramides are typically well-tolerated by most skin types, those with pre-existing sensitivities or allergies to skincare ingredients should patch-test products containing ceramides before applying them to larger areas of the skin.
If any irritation or allergic reactions occur, Ceramide complex is important to discontinue use immediately and consult a healthcare professional.
Although ceramides are naturally occurring in the skin, overuse or excessive application of ceramide-containing products may lead to skin irritation or imbalance in certain individuals.
This is especially true when ceramide products are used in combination with other active ingredients like retinoids, AHAs (alpha hydroxy acids), or BHAs (beta hydroxy acids), which may alter the skin’s natural balance.
Excessive hydration from ceramides, especially when combined with strong exfoliants or actives, can overwhelm the skin, leading to breakouts or clogged pores in some cases.
Ceramide complex is important to use ceramide products as part of a balanced skincare regimen, applying them as directed by the product’s guidelines.
While ceramides are excellent for hydrating and repairing the skin barrier, individuals with oily or acne-prone skin may find that certain ceramide products contribute to excessive oiliness or pore congestion.
Since ceramides are lipid-based molecules, they might add to the oil content of the skin, which could worsen conditions like acne or blackheads if not used in moderation.
For individuals with oily skin, it is recommended to choose oil-free or non-comedogenic ceramide products to avoid triggering breakouts or skin congestion.
Consulting with a dermatologist can help in choosing the most suitable products for acne-prone skin.
