PRODUCTS

CERAMIDE NG

Ceramide NG is used in make-up products, skin and body care for dry and mature skin.
Ceramide NG acts as a skin conditioning agent.
Ceramide NG maintains moisture and integrity of the cutaneous barrier & leaves the epidermis supple, smooth and hydrated.

CAS number: 100403-19-8
EC number: 309-560-3
Molecular formula: C₃₆H₇₃NO₃
Average molecular weight: ~ 567.98 g/mol

SYNONYMS:
Ceramide NS, Ceramide NG, N-acylated sphingolipid (sphinganine-based), “Ceramide 2 (retired name)”, mixture of ceramides, CERAMIDE NG, n-stearoyl dihydrosphingosine, Ceramide 2 pure, C04977SRJ5, Ceramide NS, 1-stearoyl-C18-sphingosine, palmitoyl-c16-dihydrosphingosine, (2S,3R)-2-(Octadecanoylamino)octadecane-1,3-diol, CERAMIDE TIC-001, Octadecanamide, N-((1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl)-, Octadecanamide, N-(2-hydroxy-1-(hydroxymethyl)heptadecyl)-, (R-(R*,S*))-, Octadecanamide, N-(2-hydroxy-1-(hydroxymethyl)heptadecyl)-, D-erythro-, DTXSID50177594, Octadecanamide, N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-, RefChem:575148, CERAMIDE NG [INCI], CERAMIDE NS [INCI], CERAMIDE 2 (RETIRED), DTXCID10100085, CERAMIDE 2 (RETIRED) [INCI], CERAMIDE 2, C18 Dihydroceramide, 2304-80-5, N-(octadecanoyl)-sphinganine, N-Stearoylsphinganine, Cer(d18:0/18:0), N-(stearoyl)-dihydroceramide, C18DH Cer, N-octodecanoylsphinganine, N-(octadecanoyl)-dihydroceramide, Ceramide II, N-stearoyldihydrosphingosine, UNII-8AD8CNQ956, N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]octadecanamide, UNII-C04977SRJ5, 8AD8CNQ956, N-stearoyldihydroceramide, N-octodecanoyldihydroceramide, N-(octodecanoyl)-sphinganine, C18 Dihydroceramide (d18:0/18:0), N-octodecanoyldihydrosphingosine, MFCD01076443, N-stearoyl-D-erythro-sphinganine, Cer(36:0), C36H73NO3, C18 Sphinganine, C18 dihydrosphingosine, N-stearoyl-sphinganine, N-(stearoyl)-sphinganine, N-[(2S,3R)-1,3-Dihydroxy-2-octadecyl]stearamide, orb1694297, SCHEMBL1478975, CHEBI:67033, Cer(36:00), N-[(1S,2R)-2-Hydroxy-1-(hydroxymethyl)heptadecyl]octadecanamide, C18-dihydro-Ceramide (N-stearoyl), LMSP02020008, AKOS040754846, DB14706, N-Stearoyldihydro-D-erythro-Sphingosine, DHC-A 18:0/18:0, BP-28818, C18 dihydro Ceramide (d18:0/18:0), SY350293, HY-141580, G91426, (2S,3R)-2-octadecanoylaminooctadecane-1,3-diol, (2S,3R)-2-octadecanoylaminooctadecane-1 ,3-diol, Q27135592, C18 Dihydroceramide (d18:0/18:0), N-stearoyl-D-erythro-sphinganine, powder

Ceramide NG (formerly known as ceramide 2) belongs to a larger group of ceramides that occur naturally in the skin as long chains of lipids (fats).
"NG" refers to the sphinganine base of this ceramide.

Healthy skin consists of approximately 50% ceramides.
Reduced levels of ceramides lead to weaker barrier strength, making the skin more vulnerable to external stressors and dehydration.
As a skin care ingredient, topical application of ceramide NG can step in to help fill this gap and replenish the skin's barrier so it is better able to defend itself against external stimuli.

Individual ceramides work best when combined with other replenishing ingredients to improve skin hydration, firmness and suppleness.
Ceramide NG is an essential skin molecule that is able to capture and bind water required by the epidermis to remain supple, smooth and hydrated.

Ceramide NG also fights against skin aging and preserves the skin's youth.
Ceramide NG provides restructuring function and maintains moisture and integrity of the cutaneous barrier.
Ceramide NG is synthetic in origin.

Ceramide NG is a dihydroceramide in which the ceramide N-acyl group is specified as octadecanoyl (stearoyl).
Ceramide NG has a role as a mouse metabolite.
Ceramide NG is a N-acylsphinganine and a N-stearoyl-sphingoid base.

Ceramide NG is functionally related to an octadecanoic acid.
Ceramide NG has been reported in Bos taurus and Averrhoa bilimbi with data available.
One of the 9 types of ceramides that can be found naturally in the upper layer of the skin.

Ceramides make up a big part (about 50%) of the goopy stuff that's between our skin cells (called extracellular matrix) and play a super important role in having a healthy skin barrier and keeping the skin hydrated.
Ceramide NG is a synthetic N-acylated sphingoid having the erythro structure.

Ceramide NG (formerly known as ceramide 2) belongs to a larger group of ceramides that are found naturally in skin as long chains of lipids (fats).
The “NG” refers to this ceramide’s sphinganine base.
Healthy skin is made up of approximately 50% ceramides.

Decreased levels of ceramides lead to weaker barrier strength, making skin more vulnerable to external stressors and dehydration.
As a skin care ingredient, topical application of ceramide NG can step in to help fill this gap and replenish skin’s barrier, so it is better able to defend itself from external stimuli.

Single ceramides work best when combined with other replenishing ingredients to improve skin’s hydration, resiliency, and suppleness.
Products rich in ceramide NG can be found in various cosmetic categories, such as moisturizers, serums, masks, and hair care products.
Additionally, ceramide NG can be found in moisturizing lotions that help restore the skin barrier and hair conditioners that strengthen hair structure.

Ceramide NG is highly valued in cosmetics because it provides long-lasting comfort and effectively protects the skin and hair from negative environmental influences.
Ceramide NG (formerly known as ceramide 2) belongs to a larger group of ceramides that are found naturally in skin as long chains of lipids (fats).

The “NG” refers to this ceramide’s sphinganine base.
Healthy skin is made up of approximately 50% ceramides.
Decreased levels of ceramides lead to weaker barrier strength, making skin more vulnerable to external stressors and dehydration.

As a skin care ingredient, topical application of ceramide NG can step in to help fill this gap and replenish skin’s barrier, so it is better able to defend itself from external stimuli.
Single ceramides work best when combined with other replenishing ingredients to improve skin’s hydration, resiliency, and suppleness.

The Cosmetic Ingredient Review Expert Panel’s 2020 assessment concluded that ceramide ingredients are safe in cosmetics in the present practices of use, typically no more than 0.01%.
Ceramide NG (N-stearoylnonhydroxy fatty acid sphingosine) represents a critical component of the skin's protective barrier, featuring a specific molecular arrangement that contributes to its specialized defensive functions.

Classified as Ceramide NG in traditional systems, this important lipid consists of a sphingosine base linked to a non-hydroxylated fatty acid chain, giving it exceptional structural stability.
Ceramide NG, also known as N-stearoylsphinganine or Ceramide 2, is similar to dermal cells' membrane molecules and is a replica of the natural type 2 ceramide that protects and repairs the cutaneous barrier of the skin.

In addition, Ceramide NG renews the skin's lipid layer, reduces transdermal moisture loss, and improves water-binding ability.
As a result, the tropical application of Ceramide NG enhances the state and appearance of human skin, preventing and reducing the visible signs of aging.

Ceramide NG is a type of Ceramide.
The NG stands for a sphinganine base.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier.

They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramides are an important building block for our skin barrier.
A stronger barrier helps the skin look more firm and hydrated.

By bolstering the skin ceramides act as a barrier against irritating ingredients.
This can help with inflammation as well.
Ceramide NG is a key lipid ingredient that helps regenerate the skin's hydrolipid barrier, protecting skin from harmful external aggressors.

Ceramide NG, a specific type of ceramide known as Ceramide 2, is a fundamental lipid molecule naturally found in the skin's outermost layer, the stratum corneum.
This essential lipid, Ceramide NG, plays a pivotal role in supporting and maintaining the skin barrier function.

USES and APPLICATIONS of CERAMIDE NG:
Ceramide NG is used in skin care can be created synthetically (aka lab engineered) or sourced naturally from plants.
Ceramide NG is used in make-up products, skin and body care for dry and mature skin.
Ceramide NG acts as a skin conditioning agent.

Ceramide NG imparts anti-aging, nourishing, strengthening, protective and barrier repairing effect.
Ceramide NG is identical to natural ceramide 2 and provides restructuring function.
Ceramide NG maintains moisture and integrity of the cutaneous barrier & leaves the epidermis supple, smooth and hydrated.

Ceramide NG also fights against skin aging and preserves the skin's youth.
Ceramide NG is used in formulating after sun, body care, eye color, face/ neck skin care, face color, foot care, leg care, lip color, nail care & color products.

Ceramide NG complies with IECIC.
Ceramide NG promotes natural, moisture-rich skin that is more likely to resist the early onset of aging.

In addition, in high-end formulas, Ceramide NG may be combined with peptides (e.g., Palmitoyl Hexapeptide-12), which enhances the effectiveness of the entire formulation, delivering better results with lower concentrations.

HOW CERAMIDE NG WORKS:
Ceramide NG's molecular configuration enables it to create particularly dense, highly organized arrangements in the intercellular lipid matrix.
These tightly packed structures enhance the overall impermeability of the skin barrier, creating a more effective shield against external threats.

While all ceramides contribute to barrier function, Ceramide NG's specific structure makes it especially effective at forming a protective, continuous barrier that prevents penetration by environmental aggressors.

KEY BENEFITS of CERAMIDE NG:
***Superior Defense Against External Threats:
Ceramide NG forms an exceptionally effective shield against pollution particles, potential pathogens, and irritating chemicals.
Research demonstrates that formulations containing adequate Ceramide NG show significantly improved resistance to barrier penetration by marker substances in laboratory testing.

***Optimized Barrier Permeability: Ceramide NG helps maintain the skin's selective permeability—allowing necessary substances in while keeping harmful elements out.
This balanced control prevents both excessive dryness and over-hydration for ideal skin function.

***Long-Term Barrier Resilience:
Ceramide NG creates particularly stable and long-lasting arrangements in the intercellular matrix, with greater resistance to breakdown by natural skin enzymes than some other ceramide types.
This provides sustained, long-term barrier support rather than just temporary improvement.

***UV Damage Protection:
While not a sunscreen, Ceramide NG helps strengthen the skin's natural defenses against UV-induced barrier damage and inflammation, complementing topical sun protection with internal resilience.

HOW CERAMIDE NG IMPROVES SKIN HYDRATION:
One of the key functions of Ceramide NG is to enhance skin hydration.
Ceramide NG does this by strengthening the lipid barrier in the stratum corneum, preventing transepidermal water loss.
This means that moisture is better retained within the skin, keeping it well-hydrated and plump.

Furthermore, Ceramide NG stimulates the production of natural moisturizing factors in the skin, such as hyaluronic acid.
These molecules are responsible for attracting and retaining water, further enhancing the skin's ability to stay moisturized.
By incorporating skincare products with Ceramide NG into your routine, you can achieve long-lasting hydration and a healthy, radiant complexion.

CERAMIDE NG IN ANTI-AGING SKINCARE:
As we age, our skin undergoes various changes that contribute to the formation of wrinkles, sagging, and dullness.
Ceramide NG can be a powerful ally in the fight against these signs of aging.
Ceramide NG's ability to strengthen the skin barrier and promote collagen production helps to improve skin elasticity and reduce the appearance of fine lines and wrinkles.

Moreover, Ceramide NG has antioxidant properties that protect the skin from free radicals, which are known to accelerate the aging process.
By incorporating Ceramide NG into your anti-aging skincare routine, you can effectively combat the signs of aging and maintain a youthful complexion.

THE SCIENCE BEHIND CERAMIDE NG AND ITS EFFECTIVENESS:
The effectiveness of Ceramide NG in skincare is backed by extensive scientific research.
Studies have shown that Ceramide NG improves skin hydration by reducing transepidermal water loss and increasing the production of natural moisturizing factors.

Furthermore, research has demonstrated that Ceramide NG enhances the skin barrier function by promoting the formation of lamellar structures, which are crucial for maintaining a healthy skin barrier.
This reinforces the skin's ability to protect against environmental stressors and retain moisture, resulting in improved skin texture and overall complexion.

HOW TO INCORPORATE CERAMIDE NG INTO YOUR SKINCARE ROUTINE:
Incorporating Ceramide NG into your skincare routine is easier than you might think.
Look for skincare products that specifically mention Ceramide NG on their ingredient list.

These can include cleansers, serums, moisturizers, and even face masks.
Start by cleansing your face with a gentle cleanser containing Ceramide NG to remove impurities without stripping your skin of its natural moisture.

Follow up with a serum or moisturizer that contains a high concentration of Ceramide NG to provide intense hydration and strengthen your skin barrier.
You can also combine Polyglyceryl-3 Polydimethylsiloxyethyl infused products with ceramides for better results.

If you have specific skin concerns, such as aging or dryness, opt for targeted treatments that combine Ceramide NG with other beneficial ingredients.

ADVANTAGES of CERAMIDE NG:
*Ceramide NG supports Skin Barrier Function
*Hydration and moisture retention
*Ceramide NG improves Skin Texture
*Ceramide NG enhances Skin Elasticity

UNDERSTANDING THE POWER of CERAMIDE NG:
Ceramide NG, also known as Ceramide 2, is a specific type of ceramide that has been scientifically proven to have exceptional benefits for the skin.
Unlike other ceramides, Ceramide NG mimics the natural structure of our skin's ceramides, making it highly compatible and easily absorbed.

This property allows Ceramide NG to replenish and strengthen the skin barrier, improving its ability to retain moisture and protect against external aggressors.
Ceramide NP, also known as Ceramide 3, is a key lipid in skincare formulations, vital for strengthening the skin barrier and maintaining optimal hydration.

Ceramide NG and Ceramide NP are distinct ceramides used in skincare formulations, with NG also known as Ceramide 2 and NP as Ceramide 3.
Both contribute to reinforcing the skin barrier, enhancing hydration, and protecting against environmental stressors, promoting overall skin health in cosmetic products.

BENEFITS OF USING SKINCARE PRODUCTS WITH CERAMIDE NG:
The use of skincare products containing Ceramide NG can bring a plethora of benefits to your skin.

**Hydration Haven:
Ceramide NG acts as a moisture-locking maestro, reinstating and sustaining optimal hydration levels.
Bid farewell to dryness and flakiness as Ceramide NG works tirelessly to keep your skin plump and luxuriously moisturized.

**Barrier Reinforcement:
Say goodbye to moisture evaporation woes.
Ceramide NG goes beyond surface-level care by fortifying the skin barrier.

Ceramide NG forms a protective shield, staunchly preventing moisture loss.
The result?
A resilient and well-protected complexion that stands up to the daily environmental challenges.

**Anti-Aging Dynamo:
Ceramide NG emerges as an age-defying ally.
Ceramide NG's remarkable anti-aging properties stimulate collagen production, enhancing skin elasticity.

Fine lines and wrinkles take a back seat as your skin undergoes a rejuvenating transformation.
Regular use promises a firmer, more resilient skin texture, unveiling a youthful radiance that defies the hands of time.

Incorporate Ceramide NG-infused skincare products into your daily ritual for a holistic approach to skincare that not only hydrates but also revitalizes, ensuring a radiant and youthful visage that stands the test of time.

CERAMIDE NG IS DEAL FOR:
*Ceramide NG delivers particularly valuable benefits for:
*Urban dwellers exposed to high pollution levels
*Significantly compromised skin barriers needing fundamental repair
*Sensitive skin requiring enhanced protection against irritants
*Acne-prone skin needing barrier support without excessive occlusion
*Skin exposed to high levels of environmental stress or professional treatments

HOW TO USE CERAMIDE NG:
After washing your face, apply a small amount of cream to cleansed skin.
Gently massage the cream in using circular motions until fully absorbed.
For best results, use morning and evening.
For best results, apply the serum before applying the cream.

FUNCTION of CERAMIDE NG IN COSMETICS:
*restorative ingredient
*moisturizing ingredient
*protective ingredient

ACTION of CERAMIDE NG IN COSMETICS:
Ceramide NG is a component of intercellular cement, it maintains skin hydration, rebuilds the hydrolipid barrier, and increases skin resistance to external factors.
Ceramide NG improves skin elasticity and slows the appearance of the first signs of aging.
Ceramide NG is also used in hair care products, providing regenerative, nourishing, and smoothing effects.

PHYSICO-CHEMICAL PROPERTIES of CERAMIDE NG:
*fatty substance
*fat-soluble

FUNCTIONS
*Hydrating
*Barrier enhancer
*Anti-aging
*Skin conditioning

BENEFITS of CERAMIDE NG:
***Reinforcement of Skin Barrier:
Ceramide NG reinforces the skin's barrier function, fortifying its resilience against external aggressors, environmental stressors, and moisture loss.
This reinforcement helps retain hydration, preventing dryness and maintaining a supple, well-hydrated skin.

***Moisture Retention and Hydration:
As a key component of the skin's natural moisture-retaining system, Ceramide NG assists in trapping moisture within the skin, supporting optimal hydration levels.
This helps combat dry, flaky skin and fosters a smoother, more plump complexion.

***Protection Against Irritants and Allergens:
A robust skin barrier, supported by Ceramide NG, acts as a shield against potential irritants and allergens.
This protective function reduces the likelihood of skin sensitivity, redness, or irritation, promoting a calmer, more comfortable skin state.

***Enhanced Skin Elasticity and Firmness:
Ceramide NG contributes to maintaining skin elasticity and suppleness.
By reinforcing the skin's structure, Ceramide NG helps diminish the appearance of fine lines and wrinkles, promoting a firmer and more youthful complexion.

***Repair and Skin Recovery:
Incorporating Ceramide NG aids in the skin's repair process, supporting recovery from damage caused by external factors or underlying skin conditions.
Ceramide NG assists in restoring the skin barrier, fostering quicker healing and skin resilience.

FUNCTIONS (INCI) of CERAMIDE NG:
*Skin conditioning - miscellaneous :
Improving the appearance of dry and/or damaged skin by reducing flaking and restoring Ceramide NG's suppleness.

CERAMIDE NG IS PRESENT IN:
Ceramide NG is present in 0.21% of cosmetics.
*Mascara (2.31%)
*Lipstick (0.6%)
*Face cream (0.54%)
*Hair conditioner (0.49%)
*Classic shampoo (0.37%)

ACTION OF CERAMIDE NG:
Nourishes the skin
Nourishes the hair
Moisturizes
Gives shine to the hair

CERAMIDE NG AT A GLANCE:
*A specific ceramide found naturally in skin that can be replicated as a cosmetic ingredient
*Works to improve skin’s barrier strength, hydration, and suppleness
*Ceramide NG is deemed a safe cosmetic ingredient by the Cosmetic Ingredient Review Expert Panel
*Formerly known as ceramide 2

HOW TO USE of CERAMIDE NG:
Ceramide NG products should be applied consistently as part of both morning and evening skincare routines to maintain continuous barrier protection.

For maximum benefit, apply to clean skin before potential irritants (active treatments, makeup) and after cleansing to restore any barrier lipids removed during the cleansing process.
Ceramide NG works particularly well in combination with antioxidants to provide comprehensive environmental protection.

FORMULATION SCIENCE of CERAMIDE NG:
The effectiveness of Ceramide NG products depends significantly on their delivery technology.
Advanced formulations utilize multi-lamellar emulsion systems or liquid crystal structures that mimic the skin's natural lipid organization, helping Ceramide NG integrate properly into the existing barrier.

The most effective products combine Ceramide NG with other ceramide types and complementary barrier lipids (cholesterol and fatty acids) in physiologically correct ratios (3:1:1).

Ceramide NG represents a fundamental ingredient for strengthening the skin's primary defensive system against environmental damage.
By enhancing the structural integrity and impermeability of the skin barrier, Ceramide NG provides protection that goes beyond surface-level effects to support the skin's fundamental health and resilience in challenging conditions.

PURPOSE AND BENEFITS of CERAMIDE NG:
Ceramide NG stands out as one of those ingredients that not only supplements but also works harmoniously with the skin’s natural processes.
Ceramide NG's unique property is its ability to restore a damaged skin barrier.

This is especially important for dry, sensitive, or stressed skin, which often loses its ability to properly protect itself from harmful environmental factors.
Ceramide NG penetrates deep into the epidermis, where it acts as a lipid “cement,” binding skin cells together and restoring the natural moisture balance.

Incorporating this ingredient into hair care products reveals another of Ceramide NG's magical properties – the ability to strengthen hair structure.
Ceramide NG helps to “seal” hair cuticles, making hair smoother, softer, and less prone to breakage.

In addition, Ceramide NG protects hair from external damage, such as heat or chemicals, ensuring its long-term health.
Regarding the effect of Ceramide NG on the skin, it is worth emphasizing its ability not only to moisturize but also to retain moisture for a long time.

This is especially important during the cold season, when the skin loses moisture due to dry air and temperature fluctuations.
Products with ceramide NG become like an invisible shield that allows the skin to feel comfortable even in the most unfavorable conditions.

Ceramide NG also reduces skin roughness and redness – an excellent choice for those with skin prone to irritation or atopy.
Using ceramide NG is like investing in the long-term beauty of skin and hair.
Ceramide NG is an ingredient that not only solves existing problems but also helps prevent new ones, providing natural radiance and protection.

SUSTAINABILITY AND EXTRACTION of CERAMIDE NG:
Ceramide NG is a synthetic ingredient, but its production can raise questions about sustainability and ethics.
In particular, the supply chain for Ceramide NG can be complex; it often involves chemical processes that can have a negative impact on the environment.

Emissions of polluting gases and chemical waste products can harm ecosystems.
In addition, if production processes are not strictly controlled, problems related to working conditions and employee rights may arise.

It is important that cosmetic manufacturers choose suppliers who adhere to sustainable practices and ethical standards to ensure that the production of Ceramide NG does not cause negative social or environmental consequences.
In this way, Ceramide NG makes it possible to achieve not only effective but also responsible products that do not harm people or the planet.

HUMIDIFIERS of CERAMIDE NG:
Ceramide NG, also known as N-oleoyl ceramide, is a valuable ingredient in cosmetics, widely used in skincare products.
The structure of Ceramide NG is similar to the skin’s natural lipids, so it can be considered as skin “guards”, helping to retain moisture and protect the skin from negative environmental influences.

Ceramide NG is a synthetic substance, but it is manufactured using advanced technologies that ensure it is safe and effective.
Its main functions are moisturizing, barrier strengthening, and increasing skin elasticity.
Using products with Ceramide NG improves skin texture, makes it look healthier, and is less prone to irritation.

Ceramide NG is an excellent choice for those who want to naturally restore and maintain the beauty of their skin, as it not only nourishes but also protects, providing long-lasting comfort.

FEATURES AND APPLICATIONS OF CERAMIDE NG:
***Skin Barrier Function:
Ceramide NG is lipids naturally found in the skin’s stratum corneum.
Ceramide NG helps maintain the skin barrier, reduce water loss (TEWL: transepidermal water loss), improve skin hydration.

***Cosmetic / Personal Care Ingredients:
Ceramide NG is widely used in moisturizers, lotions, creams, hair conditioners, etc., especially leave-on products.

***Skin Repair / Anti-Dryness:
Because ceramides are depleted in dry or damaged skin (eczema, ageing), including Ceramide NG helps restore skin lipid composition.
cir-safety.org

***Texture & Aesthetic Quality:
In creams/lotions, ceramide components like NG/NS help improve feel (richness, smoothness), reduce greasiness by being compatible with oils & lipids.

***Compatibility with Formulation Systems:
Generally compatible with typical cosmetic formulation components (emollients, oils, esters) when properly dispersed.
Because of its lipid nature Ceramide NG integrates into the lipid phase of emulsions.

***Stability:
Some ceramides are stable in formulations over time; not very volatile; relatively chemically stable under normal cosmetic conditions.
Also low photoreactivity (minimal UV/VIS absorption) meaning less risk of degradation from light under usual exposures.

FUNCTION(S) of CERAMIDE NG IN COSMETIC PRODUCTS:
*SKIN CONDITIONING - MISCELLANEOUS
Ceramide NG maintains the skin in good condition

PHYSICAL and CHEMICAL PROPERTIES of CERAMIDE NG:
CAS Number: 100403-19-8
EC Number (EINECS / Europe): 309-560-3
Molecular Formula: C₃₆H₇₃NO₃
Average Molecular Weight: ~567.98 g/mol
Appearance: Solid, crystalline (often “creamy white crystals” for certain ceramide ingredients)
Purity: Supplier listings show ~90-99.99% purity for Ceramide NG / NP / NS mixtures in some commercial samples.
Solubility: Very low solubility in water; better soluble in lipophilic / oil media (as appropriate for a ceramide)
Melting Point: For some ceramide variants (e.g. “Ceramide 2” = “Ceramide NG / NS / mixture”) about 90-100 °C

Flash Point: > 100 °C for certain ceramide variants (for safety data / cosmetic ingredients)
Molecular Weight: 568.0 g/mol
XLogP3-AA: 14.5
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 33
Exact Mass: 567.55904519 Da
Monoisotopic Mass: 567.55904519 Da
Topological Polar Surface Area: 69.6 Å²
Heavy Atom Count: 40

Formal Charge: 0
Complexity: 498
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 2
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

FIRST AID MEASURES of CERAMIDE NG:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of CERAMIDE NG:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of CERAMIDE NG:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of CERAMIDE NG:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of CERAMIDE NG:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of CERAMIDE NG:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available