PRODUCTS

CERAMIDE NP

Ceramide NP is incorporated into creams, serums, lotions, night creams especially for dry, irritated, aged, or sensitive skin.
Ceramide NP is used to condition hair, improving smoothness, reducing static or frizz, and helping restore hair fiber integrity.
Ceramide NP helps skin resist damage from environmental stress (e.g. dryness, surfactants, UV, etc).

CAS Number: 178436-06-1
EC Number: 812-963-1
Chem/IUPAC Name: (9Z)-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadec-9-enamide
Molecular formula: C₃₆H₇₁NO₄
Molecular weight (approx): ~581.96 g/mol

SYNONYMS:
Ceramide NP, Ceramide-3, N-(9Z-octadecenoyl)phytosphingosine, N-oleoyl-phytosphingosine, phytoceramide NP, Ceramide 3B, Cytomide IIIa, Cytomide IIIb, Ceramide III, Ceramide IIIB, N-octadecanoylphytosphingosine, 9-Octadecenamide, N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-, (9Z)-, N-(9Z-octadecenoyl)-4-hydroxysphinganine, OCTADECANAMIDE, N-(1,3,4-trihydroxy-2-octadecyl)-, Ceramides Mixture, N-oleoyl phytosphingosine, N-oleoyl-4-hydroxysphinganine, Cer(t18:0/18:1n-9), N-((2S,3S,4R)-1,3,4-Trihydroxyoctadecan-2-yl)oleamide, Ceramide GL(3), PHCer C18:1(n-9), N-[(2S,3S,4R)-1,3,4-Trihydroxy-2-octadecyl]oleamide, N-(9Z-octadecenoyl)-(4R)-hydroxysphinganine, Burkitt's Lymphoma associated glycolipid antigen, C18:1 Phytoceramide (t18:0/18:1(9Z)), (9Z)-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadec-9-enamide, (9Z)-N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-9-octadecenamide, (Z)-N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]octadec-9-enamide, Ceramide 3, N-Stearoyl phytosphingosine, 178436-06-1, DTXSID201319096, DTXCID301748052, UNII-4370DF050B, EINECS 309-560-3, SCHEMBL29350530, CHEBI:85204, ATGQXSBKTQANOH-UWVGARPKSA-N, AKOS040732785, DB14111, DA-62214, SY343426, TS-07726, HY-160410, CS-0928939, NS00073596, H36913, Q27158397,

Ceramide NP is one of several types of ceramides found naturally in skin.
Ceramide NP plays a critical role as a major component of skin’s outer layers (healthy skin is generally composed of 50% ceramides, many of which are of the NP variety).
“N” stands for the type of normal fatty acid correlated to this ingredient and “P” stands for its phytosphingosine base.

Ceramides used in skin care can be created synthetically or sourced naturally from plants.
Research shows skin care products containing ceramide NP can help improve the look and feel of dry or dehydrated skin thanks to its water retention properties.

Ceramide NP has also been shown to reinforce skin’s barrier strength to better resist external stressors.
Overall, Ceramide NP contributes to supple, resilient, hydrated skin.
Their survey data looked at personal care products containing concentrations up to 0.00005-0.2% ceramide NP.

Ceramide NP is composed of phytosphingosine and a saturated acid (stearic acid).
The “N” represents the normal fatty acid type correlated with this ingredient and the “P” represents its phytosphingosine base.
Ceramide NP, also known as Ceramide 3, is one of several types of ceramides naturally occurring in the skin.

Ceramides are lipid molecules found within the skin's outer layer, responsible for maintaining its barrier function and retaining moisture.
Ceramide NP is a phytoceramide in which the N-acyl group is specified as oleoyl (9Z-octadecenoyl).
Ceramide NP is functionally related to an oleic acid.

Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides.
Ceramides are major lipid components in the stratum corneum of the human skin.
Ceramide NP consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid).

Ceramide NP is widely used as a moisturizer in various cosmetic and personal products.
Together with Ceramide NP, they synergistically improve the skin barrier function in humans.
Ceramide NP is one of several types of ceramides found naturally in skin.

Ceramide NP plays a critical role as a major component of skin’s outer layers (healthy skin is generally composed of 50% ceramides, many of which are of the NP variety).
“N” stands for the type of normal fatty acid correlated to this ingredient and “P” stands for its phytosphingosine base.

Research shows skin care products containing ceramide NP can help improve the look and feel of dry or dehydrated skin thanks to its water retention properties.
Ceramide NP has also been shown to reinforce skin’s barrier strength to better resist external stressors.

Overall, Ceramide NP contributes to supple, resilient, hydrated skin.
Ceramide NP's molecular formula is C36H71NO4.
Ceramide NP is a synthetic N-acylated phytosphingosine having the erythro structure.

Ceramide NP is ISO 9001, Kosher and Halal certified.
Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides.
Ceramides are major lipid components in the stratum corneum of the human skin.

Ceramide NP consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid) 2.
Together with ceramide 1, they synergistically improve the skin barrier function in humans.
Ceramide NP is one of several types of ceramides found naturally in skin.

Ceramide NP, also known as Ceramide 3, is a specific type of ceramide, an essential lipid that naturally occurs in the skin.
It stands out from other ceramides due to its unique structure, with "N" representing the normal fatty acid linked to this ingredient and "P" denoting its phytosphingosine base.

Ceramide NP plays a critical role in maintaining skin health by reinforcing the skin's protective barrier, enhancing its ability to retain moisture, and improving its overall resilience.
Whether derived naturally from plants or created synthetically for use in skincare products, Ceramide NP has been shown to greatly improve the look and feel of dry or dehydrated skin, contributing to a supple, hydrated, and resilient skin appearance.

Ceramide NP is one of several types of ceramides found naturally in the skin.
A lipid that's found ubiquitously within our skin, Ceramide NP is particularly noteworthy because of its vital role in maintaining skin health and contributing to the look and feel of our skin.

USES and APPLICATIONS of CERAMIDE NP:
Use in Cosmetics: In skincare formulations, Ceramide NP is celebrated for its ability to reinforce the skin's natural barrier, enhance hydration, and restore a healthy skin appearance.

Ceramide NP is a key ingredient in products aimed at dry, sensitive, and aging skin, including moisturizers, serums, and targeted treatments.
Ceramide NP's role is particularly crucial in products designed to repair the skin barrier, reduce dryness, and soothe sensitive skin conditions.

Benefits for Inflammaging: Ceramide NP is highly regarded for its potential to combat "inflammaging" - chronic, low-grade inflammation that contributes to aging in the skin.
By bolstering the skin's barrier, Ceramide NP helps prevent the entry of irritants that can trigger inflammation, thereby reducing the risks associated with inflammaging and promoting a more youthful, resilient complexion.

Ceramide NP production decreases with age, which results in dry skin, wrinkles and some types of dermatitis.
Ceramides are made of a long-chain or sphingoid base linked to a fatty acid.
Sphingoids make up about half of a ceramide.

Different types of ceramides can be made, depending on which base and which fatty acids are combined.
There are at least nine different types of ceramides found in nature.
Ceramides penetrate the skin’s outer layers very well because they are “skin-identical” lipids and naturally present there.

Topically applied ceramides can move into the upper layers of the stratum corneum.
Skin conditioning / barrier repair: Ceramide NP is used in skin care products to mimic or replenish natural ceramides in the stratum corneum, helping to restore the skin barrier, reduce moisture loss, and improve hydration.

Moisturizers / lotions / creams / anti-aging cosmetics: Ceramide NP is incorporated into creams, serums, lotions, night creams especially for dry, irritated, aged, or sensitive skin.
Hair care / conditioners: Ceramide NP is used to condition hair, improving smoothness, reducing static or frizz, and helping restore hair fiber integrity.

Repairing external stressors: Ceramide NP helps skin resist damage from environmental stress (e.g. dryness, surfactants, UV, etc).
Ceramide NP acts as an anti-aging-, soothing-, moisturizing- and repairing agent.
Ceramide NP is produced by microbial fermentation process with higher purity and fewer impurities.

Ceramide NP has a strong affinity for water, can prevent the loss of water and electrolytes and has an endogenous moisturizing effect.
Ceramide NP repairs sebum membranes, reduces transepidermal water loss, increases skin moisture content and improves dry skin.
Ceramide NP helps delay skin aging and keeps skin young.

Ceramide NP reduces atopic dermatitis, scaling and relieves redness, itching and other discomforts.
Ceramide NP is used in skin care products.
Ceramide NP is widely used as a moisturizer in various cosmetic and personal products.

Ceramide NP plays a critical role as a major component of the skin's outer layers (healthy skin is generally composed of 50% ceramides, many of which are of the NP variety).
"N" stands for the type of normal fatty acid correlated to this ingredient and "P" stands for its phytosphingosine base.

Ceramide NP has also been shown to reinforce the skin's barrier strength to better resist external stressors.
Overall, Ceramide NP contributes to supple, resilient, hydrated skin.
One of the most prevalent types of ceramides found naturally in the skin

Ceramide NP can be created synthetically or sourced naturally from plants for use as a skin care ingredient
Ceramide NP helps improve the look and feel of dry or dehydrated skin thanks to its water retention propertiesCeramide NP reinforces the skin's barrier strength, so it better resists external stressors

Ceramide NP contributes to supple, resilient, hydrated skin overall
In the world of skincare, amidst an array of complex terminologies and advanced ingredients, stands Ceramide NP - a game-changer.
A lipid that naturally exists within our skin, Ceramide NP has revolutionized how we perceive and approach skin health and skincare routines.

CERAMIDE NP AT A GLANCE:
*Type of ceramide found in skin
*Reinforces skin’s barrier strength
*Ceramide NP helps improve the look and feel of dry, dehydrated skin
*Ceramide NP can be created synthetically or sourced naturally from plants for use as a skin care ingredient
*Ceramide NP contributes to supple, resilient, hydrated skin overall.

PRODUCTS WITH CERAMIDE NP:
Numerous skincare products in the market leverage the benefits of Ceramide NP.
Ceramide NP's seen in everything from face creams and serums to body lotions and eye creams.
However, it's important to opt for products that are scientifically backed and reliably reviewed, ensuring they deliver the full benefits of Ceramide NP.

Ultimately, Ceramide NP's impressive portfolio of benefits makes it an ingredient worth seeking in your skincare routine.
Ceramide NP's ability to cater to all skin types and particularly aid sensitive or compromised skin highlights its indispensable role in skincare.

THE POTENTIAL OF CERAMIDE NP FOR ECZEMA AND PSORIASIS:
In light of the connection between ceramides and skin ailments, Ceramide NP emerges as a potential hero for conditions like eczema and psoriasis.

By supplementing the skin's natural ceramide content, Ceramide NP helps to restore the barrier function of the skin, lock in moisture, and reduce dryness and inflammation.
Ceramide NP also aids in mitigating Transepidermal Water Loss (TEWL), a common problem in compromised skin conditions.

By improving the skin's water retention capability, Ceramide NP helps to keep the skin hydrated and alleviate symptoms associated with these conditions.
Moreover, Ceramide NP's ability to fortify the skin's barrier can also make the skin less susceptible to flare-ups and external irritants, providing further relief for those struggling with eczema, psoriasis, and other chronic skin conditions.

While Ceramide NP is not a cure for these conditions, it does provide significant support in managing symptoms and improving skin health.
As always, Ceramide NP's crucial to consult with a healthcare professional or dermatologist when dealing with these conditions to ensure the most effective treatment approach.

WHAT IS CERAMIDE NP USED FOR?
Ceramide NP is used in serums, creams, sunscreens, lotions, anti-aging products, night creams, oils.
Skin care:
Ceramide NP helps improve the look and feel of dry or dehydrated skin thanks to its water retention properties.
Ceramide NP also reinforces skin’s barrier strength, so it better resists external stressors and thus contributes to supple, resilient, hydrated skin overall.

ORIGIN of CERAMIDE NP:
Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides.
Ceramides are major lipid components in the stratum corneum of the human skin.
Ceramide NP consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid).

WHAT DOES CERAMIDE NP DO IN A FORMULATION?
*HAIR CONDITIONING
*MOISTURISING
*SKIN CONDITIONING

ALTERNATIVES of CERAMIDE NP:
*COCO-CAPRYLATE
*COCONUT ALKANES
*PRUNUS AMYGDALUS DULCIS OIL

One of the many types of ceramides that can be found naturally in the upper layer of the skin.
Ceramides make up about 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated.
Ceramide NP works even better when combined with its pal, Ceramide 1.

CHARACTERISTIC FORMULATION CONSIDERATIONS of CERAMIDE NP:
Since insoluble in water, Ceramide NP is used in the oil phase of formulations or encapsulated/emulsified for delivery in aqueous creams/serums.
Melting point of Ceramide NP is around 100 °C, so manufacturing / melting process must reach sufficient temperature for incorporation but must avoid overheating.

Stability with respect to oxidation: when unsaturated fatty acid parts are present (if “normal unsaturated fatty acid”) may be subject to oxidation; antioxidants might be included in the formula.
Ceramide NP is one of the most abundant ceramides found in the skin and is an important lipid component of the human skin stratum corneum.

Ceramide NP's molecular structure consists a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid).
Ceramide NP can be widely used as a moisturizer in various cosmetic and personal care products to improve human skin barrier function.

BENEFITS & CHARACTERISTICS (WHAT MAKES IT USEFUL) of CERAMIDE NP:
*Closely mimics natural skin lipids:
because Ceramide NP is very similar to ceramides found in the skin, the body recognizes it well; integration into the lipid matrix of the skin barrier is effective.
*Ceramide NP helps reduce transepidermal water loss (TEWL) because of its lipid nature, improves hydration.
*Ceramide NP supports barrier integrity, helps with repair of damaged skin barrier (e.g. due to dryness, aging, irritants).
*Ceramide NP is compatible with many cosmetic formulations — creams, oils, emulsions — especially oil-phase components since it is lipophilic.

STRUCTURE / TYPE of CERAMIDE NP:
Ceramide NP is an N-acylated sphingolipid; specifically, phytosphingosine (D-erythro stereochemistry) linked via an amide bond to a “normal” fatty acid (which may be saturated or unsaturated) — a type of “phytoceramide.

PURPOSE AND BENEFITS of CERAMIDE NP:
Ceramide NP – this is an ingredient that embodies the essence of skin care.
This unique lipid component, Ceramide NP, acts as an invisible shield, ensuring that moisture is retained in the deepest layers of the skin.
However, its effect is not limited to moisture retention – Ceramide NP also helps to restore a damaged skin barrier, which is often weakened by stress, air pollution, or improper care.

Such protection not only strengthens the skin but also reduces sensitivity, soothes irritation, and protects against external environmental threats.
On the skin’s surface, ceramide NP performs a harmonizing function – it blends perfectly with the skin’s natural lipids.

This allows Ceramide NP to act subtly and extremely effectively, without overloading the skin.
Due to this unique property, products containing ceramide NP are especially suitable for people with dry, sensitive, or redness-prone skin.

Ceramide NP also adapts perfectly to various formulas, so its benefits can be felt in face creams, night serums, or even hair care products.
Speaking of hair, ceramide NP acts as a revitalizer for damaged and dry hair.

Ceramide NP's inclusion in shampoos or conditioners strengthens the hair structure, reduces breakage, and improves resistance.
Ceramide NP is an ingredient that not only takes care of appearance but also deep health – both skin and hair.

Another feature of Ceramide NP is its ability to even out skin texture.
Using products with ceramide NP, the skin becomes smoother, more even, and its surface looks more balanced.
Ceramide NP is not only a solution for dry skin but also a preventive measure to help maintain youthful skin condition.

CERAMIDE NP AT A GLANCE:
*One of the most prevalent types of ceramides found naturally in skin.
*Ceramide NP can be created synthetically or sourced naturally from plants for use as a skin care ingredient.
*Ceramide NP helps improve the look and feel of dry or dehydrated skin thanks to its water retention properties.
*Ceramide NP reinforces skin’s barrier strength, so it better resists external stressors.
*Ceramide NP contributes to supple, resilient, hydrated skin overall.

FUNCTION(S) of CERAMIDE NP IN COSMETIC PRODUCTS
*HAIR CONDITIONING
Ceramide NP leaves the hair easy to comb, supple, soft and shiny and / or imparts volume

*SKIN CONDITIONING - MISCELLANEOUS
Ceramide NP maintains the skin in good condition

BENEFITS OF CERAMIDE NP:
*Perfect for Dry and Dehydrated Skin
*One of the significant advantages of Ceramide NP lies in its ability to revolutionize the condition of dry or dehydrated skin.
*As a critical part of the skin's natural composition, Ceramide NP works effectively to restore and rehydrate the skin.

Ceramide NP's restorative properties help replenish the skin's natural ceramides, thereby fortifying the skin's barrier, reducing dryness, and enhancing the skin's overall texture and appearance.

MAGIC OF WATER RETENTION of CERAMIDE NP:
Ceramide NP shines in its water retention properties.
This vital function allows it to hold on to precious moisture, helping to prevent transepidermal water loss (TEWL), a common issue in compromised skin conditions.
This crucial capability means Ceramide NP can help the skin stay hydrated, maintain its plumpness, and reduce signs of aging like fine lines and wrinkles, leading to a more youthful and radiant appearance.

REINFORCING THE SKIN'S BARRIER STRENGTH of CERAMIDE NP:
The reinforcing power of Ceramide NP should not be underestimated.
By strengthening the skin's barrier, Ceramide NP enhances its resistance against environmental stressors such as pollution and UV rays.
In essence, Ceramide NP serves as a crucial support pillar for your skin.
Its restorative, hydrating, and strengthening capabilities make Ceramide NP an essential ingredient in any effective skincare routine.

INTEGRATING CERAMIDE NP IN SKINCARE PRODUCTS:
Ceramide NP has found its rightful place in the realm of skincare, thanks to its benefits.
Ceramide NP is integrated into skincare products in different forms — either synthesized in laboratories or naturally sourced from plants.

Regardless of its origin, Ceramide NP's purpose in skincare products is to deliver its hydration, restoration, and barrier strengthening benefits to your skin.
Ceramide NP's often found in moisturizers, serums, and other skin treatments where it works to lock in moisture, improve skin texture, and boost the skin's overall health.

GREAT FOR ALL SKIN TYPES of CERAMIDE NP:
Ceramide NP serves works well for all skin types, but it is particularly beneficial for sensitive or compromised skin.
Ceramide NP helps to reinforce the skin's barrier, soothes irritation, and reduces the tendency for flare-ups in conditions like eczema and psoriasis.
For normal skin types, Ceramide NP helps maintain a healthy skin barrier, keeps skin hydrated, and prevents the signs of premature aging.

KEY BENEFITS OF CERAMIDE NP IN SKIN CARE:
*Moisturizing and hydration
*Restore barrier function
*Ceramides are a type of lipid that is abundant in skin tissue, where it exerts both structural and signaling functions.
*Ceramide NP's structural function includes maintaining the barrier function and retaining water content and hence integrity of the skin.
*Ceramide NP's signaling function includes regulating the proliferation, differentiation, and apoptosis of the cells.

Ceramides have been used to treat skin conditions that are a result of disrupted barrier function, such as atopic dermatitis, irritant/allergic contact dermatitis, and aged skin, and they might be used against skin cancer as well.
This is an easy to use and predispersed ceramide NP.

Ceramides are part of our own skin barrier and have proved in clinical studies to reduce TEWL, enhance skin hydration, reduce wrinkles and inflammation and enhance the barrier function.

The commercially available ceramides are either in powder form that need to be heated over a long time around 90 C or an easy to use liquid form dispersed in mineral oil and/or preserved with parabens or phenoxyethanol.

This easy to use fluid, non-preserved ceramide NP comes in a carrier derived from olive oil (palm oil free) and you can apply it at temperatures as low as 40 C.
No need to cook the ceramide and other precious ingredients in order to incorporate the ceramide.

Ceramides NP, also known as ceramide 3, are natural lipid molecules that play an essential role in skin health.
They help restore the skin barrier by retaining moisture and protecting against adverse environmental factors.

The structure of these ceramides resembles the lipid components of the skin, allowing them to penetrate and act effectively.
Ceramides NP are derived from natural sources, usually plants, or synthetically, and are used in various cosmetic products, such as creams, lotions, and serum formulas.

Their benefits are obvious: they help reduce dryness, give the skin elasticity and smoothness, and promote its regeneration.
Using products containing Ceramide NP can help you achieve healthier and more radiant skin.

THE FORMATION AND UNIQUE PROPERTIES OF CERAMIDE NP:
Ceramide NP's distinctive character comes from its structure.
The 'NP' in Ceramide NP stands for its normal fatty acid and phytosphingosine base, distinguishing it from other ceramides.
Ceramides in skincare products can either be derived from natural plant sources or synthesized in laboratories.
Either way, their function remains the same — to bolster the skin's barrier and improve its overall appearance.

PREVALENCE AND IMPORTANCE OF CERAMIDE NP IN SKIN:
Ceramide NP is one of the most prevalent types of ceramides naturally present in our skin.
Ceramide NP makes up a significant proportion of the ceramides found in the outer layers of healthy skin.

Ceramide NP's water-retention properties greatly contribute to improving the look and feel of dry or dehydrated skin.
Ceramide NP also plays a crucial role in reinforcing the skin's barrier strength, enabling it to better resist external stressors and retain moisture.

This contributes to supple, resilient, and hydrated skin, making Ceramide NP an essential player in skin health and vitality.
Understanding Ceramide NP is a window into understanding the science of skincare, as it holds the key to healthier, more resilient skin.
Ceramide NP's truly a testament to the role of science in beauty.

HOW CERAMIDE NP WORKS:
Ceramide NP is an exceptionally pure ceramide containing a stereochemical structure identical to those found in the human skin.
Not only does Ceramide NP reinforce the natural lipid barrier of dry and aging skin, it also shows an outstanding ability to maintain the moisture balance of the skin’s surface.

Ceramides are a type of wax that’s naturally found in our skin.
The name came from the Latin cera which means wax.

Ceramides form a kind of water-proofing barrier in the upper layers of the skin.
They’re not only critical for helping the skin retain water, but they also help repair the skin’s natural barrier and regulate the cells.

Their signaling function includes regulating the proliferation, differentiation, and apoptosis of the cells.
Ceramides have been used to treat skin conditions that are a result of a disrupted barrier function, such as atopic dermatitis, irritant/allergic contact dermatitis, and aged skin.

WHAT ARE CERAMIDES?
Ceramides are a type of lipid (fat) that are naturally produced in our bodies.
These unsung heroes of skin health form an integral part of the skin's structure, working quietly behind the scenes to maintain the integrity and health of our skin.

THE ROLE OF CERAMIDE NP IN SKIN HEALTH
Ceramides have a crucial role to play in skin health.
They work much like the 'mortar' in a brick and mortar structure - with skin cells being the 'bricks'.

Ceramides constitute approximately 50% of this 'mortar', highlighting their significant role in moisture retention, pathogen resistance, and prevention of premature aging.
Simply put, ceramides are responsible for keeping our skin strong, resilient, and waterproof.

CERAMIDE NP AND THE SKIN'S MOISTURE BARRIER
One of the primary roles of ceramides is to maintain the health and integrity of the skin's moisture barrier.
This barrier acts as the skin's first line of defense against environmental stressors such as pollution, UV rays, and hard water.

An imbalance or lack of ceramides can lead to a compromised skin barrier, potentially leading to dryness, irritation, and other skin conditions such as eczema and psoriasis.

In essence, the ceramides serve as the protective shield of your skin, reinforcing the skin's barrier, locking in essential moisture, and helping prevent skin ailments.
Understanding the function and importance of ceramides, particularly Ceramide NP, is a crucial step towards a healthier and more effective skincare routine.

PHYSICAL and CHEMICAL PROPERTIES of CERAMIDE NP:
CAS Number: 178436-06-1
EC Number: 812-963-1
Chem/IUPAC Name: (9Z)-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadec-9-enamide
Molecular formula: C₃₆H₇₁NO₄
Molecular weight (approx): ~581.96 g/mol
Appearance: Usually a white to off-white crystalline or waxy solid / powder
Melting point: ~98-110 °C
Solubility: Insoluble in water; soluble in oils and some fatty alcohols
Lipophilicity (Log P) / Partition behaviour: Very high (i.e. highly lipophilic) —
it has strong affinity for lipid phases

Chemical stability: Stable under normal conditions of storage and formulation when protected from extreme heat, oxidation, etc.
Derivative of a natural lipid; the amide bond and multiple hydroxyls confer some reactivity (e.g. esters, oxidation) but generally stable.
Molecular Weight: 582.0 g/mol
XLogP3-AA: 12.4
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 32
Exact Mass: 581.53830975 Da
Monoisotopic Mass: 581.53830975 Da
Topological Polar Surface Area: 89.8 Å²

Heavy Atom Count: 41
Formal Charge: 0
Complexity: 568
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 3
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 1
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance: White to off-white powder

Melting Point: Approximately 72–74°C
Boiling Point: Not applicable (decomposes before boiling)
Density: Approximately 0.982 g/cm³ at 20°C
Solubility: Insoluble in water; soluble in organic solvents like ethanol and chloroform
pKa: Approximately 13.65 (predicted)
LogP (Octanol/Water): Approximately 11.79 at 25°C and pH 7
Vapor Pressure: Negligible at 25°C
Flash Point: Not applicable (decomposes before flash point)
Refractive Index: Approximately 1.45

FIRST AID MEASURES of CERAMIDE NP:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of CERAMIDE NP:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of CERAMIDE NP:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of CERAMIDE NP:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of CERAMIDE NP:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of CERAMIDE NP:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available