Quick Search
CETEARETH-10 PHOSPHATEs precursor is a high molecular weight alcohol of natural origin, that is mostly present in vegetables.
CETEARETH-10 PHOSPHATE is a mixture of cetyl and stearyl alcohols which are ethoxylated with ten moles of ethylene oxide.
CETEARETH-10 PHOSPHATE is a synthetic, anionic surfactant and emulsifier that is derived from a combination of cetyl and stearyl alcohols (long-chain fatty alcohols from natural or synthetic sources) which are then ethoxylated with an average of ten ethylene oxide units and finally phosphorylated to create a phosphate ester.
CAS Number: 106233-09-4
EINECS Number: 500-295-0
Synonyms: Ceteareth-10 phosphate, 099WOY1SA3, CETEARETH-10 PHOSPHATE [INCI], RefChem:575297Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, mono-C16-18-alkyl ethers, phosphates, C16-18 alcohols, ethoxylated, phosphates, Alcohols, C16-18, ethoxylated, phosphates
CETEARETH-10 PHOSPHATE refers to a PEG (polyethylene glycol-) ether of cetyl alcohol.
The number behind CETEARETH-10 PHOSPHATE" refers to the average number of molecular units -CH2-CH2-O-.
CETEARETH-10 PHOSPHATE is the INCI name for a surfactant whose structure belongs to the group of commonly used derivatives of ethoxylated fatty alcohols.
This non-ionic surfactant meets all the strict quality requirements set out in the European Pharmacopoeia which are defined on account of the pharmacy code.
Thus CETEARETH-10 PHOSPHATE is classified as part of the Macrogol Cetostearyl Ether group.
Moreover, this chemical substance is safe for use in cosmetic formulations without any restrictions.
The CAS number allowing for the global identification of Ceteareth-10 is 68439-49-6.
CETEARETH-10 PHOSPHATE is a phosphate-modified fatty alcohol ethoxylate used as an emulsifier and stabilizer in creams, lotions, and other personal care formulations.
It is created by combining long-chain fatty alcohols with ethylene oxide and phosphate groups, giving it strong oil-in-water emulsifying properties and making it especially effective in keeping products smooth, stable, and cosmetically elegant.
The structure of this compound gives it a dual-functionality: the fatty alcohol portion provides a lipophilic (oil-loving) tail that anchors into oils and fats, while the ethoxylated phosphate group provides a hydrophilic (water-loving, negatively charged) head that interacts with water.
This amphiphilic nature allows CETEARETH-10 PHOSPHATE to act as a powerful emulsifier, helping to mix oil and water into stable formulations that do not separate over time.
CETEARETH-10 PHOSPHATE is often supplied and used in combination with its neutralized salts, such as disodium cetearyl phosphate, because the salt form improves solubility and stability in formulations.
This modification also makes it more versatile in cosmetic and pharmaceutical applications where long-term stability and mildness are required.
From a functional perspective, CETEARETH-10 PHOSPHATE is valued because it provides excellent emulsifying power even at relatively low concentrations, meaning that formulators can create lightweight creams and lotions that feel elegant and smooth on the skin.
Its phosphate group also adds a certain degree of ionic stabilization, which helps emulsions resist breakdown under stress conditions such as heating, cooling, or mechanical mixing.
This ingredient is commonly found in cosmetics, personal care products, and dermatological creams, where it serves as both a primary emulsifier and a stabilizer.
Unlike simple Ceteareth compounds (such as Ceteareth-16 or Ceteareth-23), which are nonionic, the phosphate derivative carries a negative charge, which changes its interaction with other ingredients and sometimes makes it more compatible with charged active ingredients.
vapor pressure: 0.005Pa at 25℃
Odor: at 100.00?%. bland
CETEARETH-10 PHOSPHATE is a phosphate ester of a C16–C18 fatty alcohol ethoxylate, meaning it is chemically derived from cetyl and stearyl alcohols that are first reacted with 10 moles of ethylene oxide, and then phosphorylated to produce the final anionic compound.
The phosphate group gives the molecule a negative charge, which distinguishes it from standard nonionic ceteareths like Ceteareth-10 or Ceteareth-16.
This negative charge allows it to interact electrostatically with positively charged ingredients in a formulation, such as certain cationic polymers, active pharmaceutical agents, or conditioning agents in hair products.
Its amphiphilic nature — with a long lipophilic tail and a hydrophilic phosphate head — allows it to reduce surface tension between oil and water, creating a stable interface that prevents the two phases from separating.
This makes CETEARETH-10 PHOSPHATE an excellent emulsifier for oil-in-water creams and lotions, and also contributes to enhanced stability in emulsions under varying temperatures and shear conditions.
CETEARETH-10 PHOSPHATE are poly condensation products of ethylene glycol, or polymerisation products of ethylene oxide.
The number added to the name refers to the mean number of ethylene oxide units in the substance.
The consistency of the CETEARETH-10 PHOSPHATE derivatives is increasingly solid with a growing degree of polymerisation.
CETEARETH-10 PHOSPHATEs with a mean molar mass of up to 600 g/mol are liquid, up to 1,000 g/mol wax-like and from 4,000 g/mol solid wax-like substances.
By mixing solid and liquid components, products of a creamy consistency are obtained which are used as water-free and water rinse-off bases.
With growing molar mass water solubility and hygroscopicity (ability to absorb moisture) of the polyethylene glycols decrease.
CETEARETH-10 PHOSPHATE is a phosphate-modified fatty alcohol ethoxylate that acts as a highly effective emulsifier and stabilizer in cosmetics, personal care, and pharmaceutical formulations.
CETEARETH-10 PHOSPHATEs phosphate group provides ionic stabilization, allows compatibility with cationic ingredients, and enhances the stability, texture, and sensory properties of creams, lotions, and hair care products.
This makes it a versatile ingredient for high-performance, elegant, and durable formulations.
CETEARETH-10 PHOSPHATE is particularly valuable in formulations that include multiple oils, waxes, esters, silicones, or sensitive botanical extracts, where maintaining a stable oil-in-water emulsion is challenging.
Its phosphate group allows the emulsifier to provide extra electrostatic stabilization, reducing the risk of separation during storage or under fluctuating temperatures, and ensuring that the product remains visually appealing and effective throughout its shelf life.
Because it is anionic and phosphate-modified, CETEARETH-10 PHOSPHATE is often used in products designed for sensitive or delicate skin, including baby lotions, facial creams, and hypoallergenic formulations.
CETEARETH-10 PHOSPHATE provides effective emulsification without the harshness associated with high-surfactant or ionic detergents, which helps prevent irritation, dryness, or over-stripping of natural skin oils.
In hair care products such as leave-in conditioners, hair masks, and shampoos with conditioning benefits, CETEARETH-10 PHOSPHATE helps evenly disperse oils, silicones, and conditioning polymers.
Its mildness and negatively charged phosphate group also help maintain hair shaft integrity and cuticle smoothness, contributing to improved manageability, shine, and detangling properties.
The negative charge on the phosphate head makes CETEARETH-10 PHOSPHATE compatible with cationic conditioning agents, peptides, or antimicrobial polymers that might otherwise precipitate or destabilize an emulsion if mixed with nonionic surfactants alone.
This makes it extremely useful in multi-functional skincare, hair care, and medicated formulations.
Uses Of CETEARETH-10 PHOSPHATE:
CETEARETH-10 PHOSPHATE is widely used in facial creams, body lotions, sunscreens, and anti-aging products because it can combine water and oils into a smooth, stable emulsion.
Its ability to form stable emulsions with relatively low concentrations makes it cost-effective while providing a luxurious, light, and non-greasy skin feel.
When formulations include multiple oils, esters, silicones, or sensitive active ingredients, CETEARETH-10 PHOSPHATE acts as a stabilizing agent, maintaining emulsion integrity over time and preventing separation.
This is particularly important in products that must maintain quality during storage and shipping across different climates.
Its mildness and negative charge make it compatible with hair conditioners, leave-in creams, and hair masks, where it helps evenly disperse conditioning oils and active ingredients while preventing excessive greasiness.
Its phosphate group can also slightly improve the detangling effect of formulations.
In some formulations, CETEARETH-10 PHOSPHATE is combined with other nonionic or amphoteric emulsifiers to fine-tune texture, viscosity, and skin feel.
This allows formulators to adjust the balance between hydrophilic and lipophilic properties to achieve the desired sensory and functional characteristics.
In medicinal creams and ointments, CETEARETH-10 PHOSPHATE improves spreadability, uniform distribution of active ingredients, and emulsion stability, ensuring consistent therapeutic performance and patient comfort.
The negative charge of the phosphate group allows CETEARETH-10 PHOSPHATE to be formulated with cationic actives, peptides, or conditioning polymers, which might be destabilized by nonionic emulsifiers alone.
This makes it a versatile choice for complex, multi-ingredient formulations.
CETEARETH-10 PHOSPHATE is extensively used in creams, lotions, and serums to combine oil and water into a stable, homogeneous emulsion.
Its phosphate group provides a negative charge that not only helps stabilize the emulsion but also ensures that oils, waxes, and water remain evenly distributed over time, preventing phase separation even under stress from temperature changes or mechanical agitation.
Because it is mild and anionic, CETEARETH-10 PHOSPHATE is particularly suitable for products designed for sensitive or delicate skin, including baby lotions, hypoallergenic creams, and facial moisturizers.
CETEARETH-10 PHOSPHATE provides emulsification without the harshness associated with traditional ionic surfactants, helping to maintain the natural skin barrier and reduce the risk of irritation or dryness.
In products that include multiple oils, silicones, esters, or active ingredients, CETEARETH-10 PHOSPHATE acts as a stabilizing agent that prevents separation and ensures consistent texture, appearance, and performance.
This is especially important in high-end cosmetic and dermatological creams, where product integrity over extended shelf life is critical.
CETEARETH-10 PHOSPHATE is used in conditioners, leave-in treatments, hair masks, and styling products where it helps disperse oils, silicones, and conditioning agents evenly throughout the formulation.
Its phosphate group interacts with hair fibers to provide improved detangling, softness, and smoothness, while preventing a heavy or greasy feel.
In formulations that include essential oils, botanical extracts, or lipid-soluble active ingredients, CETEARETH-10 PHOSPHATE serves as a co-surfactant or solubilizer, helping these components mix uniformly with the water phase.
This ensures consistent performance, appearance, and fragrance distribution across the product.
In topical medications and dermatological products, CETEARETH-10 PHOSPHATE is used to stabilize the emulsion, improve spreadability, and evenly distribute active pharmaceutical ingredients (APIs).
This contributes to consistent dosing, enhanced patient comfort, and effective delivery of therapeutic compounds, particularly in creams intended for anti-inflammatory, analgesic, or barrier-protective purposes.
The negative charge of the phosphate group allows CETEARETH-10 PHOSPHATE to work effectively with cationic polymers, peptides, and other charged actives, which might otherwise destabilize a formulation if used with nonionic emulsifiers alone.
This makes it a versatile ingredient for multi-functional, high-performance cosmetic and hair care products.
In sunscreen formulations, CETEARETH-10 PHOSPHATE helps maintain uniform dispersion of oil-soluble UV filters and water-soluble humectants, ensuring stable and consistent sun protection while maintaining a light, non-greasy skin feel.
Though primarily used in leave-on formulations, it can also be included in creamy cleansers or makeup removers to assist in dispersing oils and residues into water for effective cleansing without causing harshness or dryness.
Safety Profile Of CETEARETH-10 PHOSPHATE:.
CETEARETH-10 PHOSPHATE is generally considered mild when properly formulated in creams, lotions, or hair care products.
However, at high concentrations or in raw form, it can cause mild to moderate irritation to the skin and eyes, particularly in individuals with sensitive skin or pre-existing conditions such as eczema.
Irritation may manifest as redness, itching, or stinging, especially if the product is left on the skin for extended periods or applied to broken or inflamed skin.
As a phosphate-modified surfactant, CETEARETH-10 PHOSPHATE has penetration-enhancing properties, meaning it can increase the skin’s permeability.
While this is useful for delivering beneficial active ingredients, it can also increase the absorption of residual contaminants, such as trace amounts of solvents, unreacted ethylene oxide, or other impurities, if present in the formulation.
This is why proper purification during manufacturing is critical to minimize risk.
CETEARETH-10 PHOSPHATE is produced by ethoxylating fatty alcohols, which can leave behind trace levels of 1,4-dioxane and ethylene oxide.
Both substances are considered potentially hazardous: 1,4-dioxane is a probable human carcinogen, and ethylene oxide is a known carcinogen and respiratory irritant.
Manufacturers typically remove these by-products through purification, but insufficient purification can pose a chronic health risk over long-term exposure.
