CETYL LACTATE

Synonyms:

Hexadecyl 2-hydroxypropanoate; Hexadecyl lactate; 35274-05-6; CETYL LACTATE; hexadecyl 2-hydroxypropanoate; Propanoic acid, 2-hydroxy-, hexadecyl ester; UNII-A7EVH2RK4O; A7EVH2RK4O; HexadecylLactate; n-Hexadecyl lactate; EINECS 252-478-7; 2-Hydroxypropanoic acid hexadecyl ester; AI3-14483
Propanoic acid,2-hydroxy-, hexadecyl ester; ACMC-1AJ3N; Lactic acid hexadecyl ester; DHL-C70; Ceraphyl 28;Liponate CL; CETYL LACTATE; Ctetyl lactate; Palmityl lactate; HEXADECYL LACTATE; n-Hexadecyl lactate; HexadecylLactate>CH3CH(OH)COO(CH2)15CH3 ; SCHEMBL33964; Hexadecyl 2-Hydroxypropionate; hexadecyl lactate, AldrichCPR; n-Hexadecyl-2-hydroxypropanoate; CTK4H4156; DTXSID20865759; ANW-28162; AKOS027321017; 2-Hydroxypropionic acid hexadecyl ester; Cetyl Lactate; Lacticacid; 2-hidroksi-propanoikasiteksadekillerter, 2-Hidroksipropionik asit heksadesil ester, Ceraphyl 28, D, L-Lacticacidhexadecilester; Lactic acid cetyl ester; Liponate CL; Propanoik asit, 2-hidroksi-, heksadecyl ester; Propanoik asit, 2-hidroksi-, heksadesekter; Hexadecyl Ester (7CI); Cetyl Lactate; Cyclochem CL; Hexadecyl Lactate; Unitate CL; KS-0000176N; Q27273721; setil laktat; cetyl laktate; setyl lactate; setyl lactate; cetil lactac; SETİL LAKTAT ; CETYL LACTAT; CETYLE LACTATE; SETYL LACTAT; SETYLE LACTATE

CETYL LACTATE

Cetyl Lactate

What Is Cetyl Lactate?
Glycolic Acid and Lactic Acid are naturally occuring organic acids also known as Alpha Hydroxy Acids or AHAs. The salts of Glycolic Acid (Ammonium Glycolate, Sodium Glycolate), the salts of Lactic Acid (Ammonium Lactate, Calcium Lactate, Potassiu Lactate, Sodium Lactate, TEA-Lactate) and the esters of Lactic Acid (Methyl Lactate, Ethyl Lactate, Butyl Lactate, Lauryl Lactate, Myristyl Lactate, Cetyl Lactate) may also be used in cosmetics and personal care products. In cosmetics and personal care products, these ingredients are used in the formulation of moisturizers, cleansing products, and other skin care products, as well as in makeup, shampoos, hair dyes and colors and other hair care products.

Why is Cetyl Lactate used in cosmetics and personal care products?
The following functions have been reported for Glycolic Acid, Lactic Acid and their salts and esters.

Buffering agent - Ammonium Lactate, Potassium Lactate, Sodium Lactate
Cosmetic astringent - Calcium Lactate
Exfoliant - Glycolic Acid, Lactic Acid, Ammonium Glycolate, Ammonium Lactate, Calcium Lactate, Potassium Lactate, Sodium Lactate
Humectant - Lactic Acid
pH adjuster - Glycolic Acid, Lactic Acid, Ammonium Glycolate, Sodium Glycolate
Skin conditioning agent - emollient - Lauryl Lactate, Myristyl Lactate, Cetyl Lactate
Skin conditioning agent - humectant - Lactic Acid, Ammonium Lactate, Potassium Lactate, Sodium Lactate, TEA-Lactate
Skin conditioning agent - miscellaneous - Lactic Acid
Solvent - Methyl Lactate, Ethyl Lactate, Butyl Lactate
Scientific Facts: 
Glycolic Acid and Lactic Acid are alpha hydroxy acids (AHAs). They may be either naturally occurring or synthetic. They are often found in products intended to improve the overall look and feel of the skin. Glycolic acid is the most widely used of out of the group and is usually manufactured from sugar cane. Lactic acid, derived primarily from milk and its origins can be traced back to Cleopatra, who purportedly used sour milk on her skin.

CETYL LACTATE
CETYL LACTATE is classified as :
Emollient
Skin conditioning
CAS Number    35274-05-6
EINECS/ELINCS No:    252-478-7
COSING REF No:    74961
Chem/IUPAC Name:    Hexadecyl 2-hydroxypropanoate

Cetyl lactate
Smooths and softens skin and hair. It is used as a material in many creams and cosmetics.

Basic Information
Cetyl/myristyl lactate is a white, wax-like solid made from lactic acid and esters of cetyl/myristyl alcohols. It is used as a skin lubricant and emollient with excellent softening properties, which makes skin and hair soft to the touch. It reduces glare, stickiness, and other effects of oil while also helping to prevent drying from alcohols and protect skin and hair. It also helps promote skin absorption of pharmaceuticals.

1．Description    
It is a white solid with no odor.    
It is a soft, white solid and is odorless or has a peculiar smell. Highly soluble in ethanol (95%) and diethyl ether. Almost insoluble in water.

2．Identification Test
    
（1）Reacts with lactic acid salt.    （1）Reacts with lactic acid salt.
（2）Hydroxyl value is between 210 to 240.    （2）Hydroxyl value is between 210 to 240.

Specific gravity    
d3025 0.893 - 0.905 (Water at 30 ℃/25 ℃)    
d3025 0.885 - 0.897 (Water at 40 ℃/25 ℃)

Acid value    
No more than 2.0    
No more than 2.0

6．Saponific value    
174 - 189    
174 - 189

7．Melting Point    
37 - 44℃    
37 - 44℃

8．Residue on Ignition    
0.10% or less    
0.10% or less

Product Testing Method
General Use
Testing methods in accordance with the section on medical product raw material standards for cetyl lactate or with general testing methods.
Pharmaceuticals Additive
UseTesting methods in accordance with the section on Japanese Non-official Pharmaceuticals Standards and Pharmaceuticals Additive Standards for cetyl lactate.

CETYL LACTATE Properties
Melting point:41 °C
Boiling point:bp0.1 132°; bp1 170°; bp10 219°
Density 1.0196 (rough estimate)
FEMA 4483 | HEXADECYL LACTATE
refractive index nD40 1.4410; nD50 1.4370
pka13.05±0.20(Predicted)
JECFA Number1950
Merck 14,2030
Substances Added to Food (formerly EAFUS)HEXADECYL LACTATE
EWG's Food Scores1-4
FDA UNIIA7EVH2RK4O
NIST Chemistry Referencehexadecyl lactate(35274-05-6)

Uses
Nonionic emollient. To improve feel and texture of cosmetic and pharmaceutical preparations.

APPEARANCE
White to off-white flakes with a faint fatty buttery odor
DESCRIPTION
Used in lipsticks, mascaras, nail polish removers, hand lotions, cream, rouges and many other cosmetics, shampoos, hair lacquers and other hair products, deodorants, antiperspirants.
FUNCTION
Cetyl lactate can be used as solid flavors and oil-soluble pharmaceutical additive solubilizers. Also applies to the oily components of cosmetics, bath, etc.
SYNONYMS
Cetyl Lactate; Lacticacid; Hexadecyl Ester (7CI); Cetyl Lactate; Cyclochem CL; Hexadecyl Lactate; Unitate CL
STORAGE
Keep container tightly closed. Store in areas away from light/sunlight and keep below room temperature.

Molecular Weight of Cetyl Lactate:314.5 g/mol    Computed by PubChem 2.1 (PubChem release 2019.06.18)
XLogP3-AA of Cetyl Lactate:    7.6    Computed by XLogP3 3.0 (PubChem release 2019.06.18)
Hydrogen Bond Donor Count of Cetyl Lactate:    1    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Hydrogen Bond Acceptor Count of Cetyl Lactate:    3    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Rotatable Bond Count of Cetyl Lactate:    17    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Exact Mass of Cetyl Lactate:    314.282095 g/mol    Computed by PubChem 2.1 (PubChem release 2019.06.18)
Monoisotopic Mass of Cetyl Lactate:    314.282095 g/mol    Computed by PubChem 2.1 (PubChem release 2019.06.18)
Topological Polar Surface Area of Cetyl Lactate:    46.5 Ų    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Heavy Atom Count of Cetyl Lactate:    22    Computed by PubChem
Formal Charge of Cetyl Lactate:    0    Computed by PubChem
Complexity of Cetyl Lactate:    241    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Isotope Atom Count of Cetyl Lactate:    0    Computed by PubChem
Defined Atom Stereocenter Count of Cetyl Lactate:    0    Computed by PubChem
Undefined Atom Stereocenter Count of Cetyl Lactate:    1    Computed by PubChem
Defined Bond Stereocenter Count of Cetyl Lactate:    0    Computed by PubChem
Undefined Bond Stereocenter Count of Cetyl Lactate:    0    Computed by PubChem
Covalently-Bonded Unit Count of Cetyl Lactate:    1    Computed by PubChem
Compound  of Cetyl Lactate Is Canonicalized    Yes