Quick Search
Chlorhexidine Digluconate is a water-soluble salt of chlorhexidine widely used as a broad-spectrum antimicrobial agent in medical, pharmaceutical, dental, cosmetic, veterinary, and industrial applications.
Chlorhexidine Digluconate exhibits rapid and persistent antibacterial activity against Gram-positive and Gram-negative bacteria, as well as antifungal efficacy against yeasts.
Chlorhexidine Digluconate is valued for its strong residual effect on skin and mucous membranes, high aqueous solubility, and formulation versatility.
CAS Number: 18472-51-0
EC Number: 242-354-0
Molecular Formula: C₂₂H₃₀Cl₂N₁₀ · 2C₆H₁₂O₇
Molecular Weight: ~897.76 g/mol
Synonyms: Chlorhexidine Digluconate, Chlorhexidine Gluconate, CHG, Chlorhexidine Digluconate Solution, Chlorhexidine Digluconate, Chlorhexidine Gluconate, Chlorhexidine Gluconate Solution, CHDG, CHG (solution reference), Chlorhexidine Digluconate Solution, Chlorhexidine Digluconate Antiseptic, Chlorhexidine Digluconate Antimicrobial, Chlorhexidine Digluconate Disinfectant, Chlorhexidine Digluconate Bactericidal Agent, Chlorhexidine Digluconate Bacteriostatic Agent, Chlorhexidine Digluconate Germicide, Chlorhexidine Digluconate Biocide, Chlorhexidine Digluconate Broad-Spectrum Antiseptic, Chlorhexidine Digluconate Broad-Spectrum Antimicrobial, Chlorhexidine Digluconate Infection Control Agent, Chlorhexidine Digluconate Hospital Antiseptic, Chlorhexidine Digluconate Medical Antiseptic, Chlorhexidine Digluconate Clinical Antiseptic, Chlorhexidine Digluconate Surgical Antiseptic, Chlorhexidine Digluconate Surgical Scrub Agent, Chlorhexidine Digluconate Preoperative Skin Prep, Chlorhexidine Digluconate Healthcare Antiseptic, Chlorhexidine Digluconate Dermatological Antiseptic, Chlorhexidine Digluconate Skin Antiseptic, Chlorhexidine Digluconate Wound Antiseptic, Chlorhexidine Digluconate Oral Antiseptic, Chlorhexidine Digluconate Dental Antiseptic, Chlorhexidine Digluconate Mouth Rinse Active, Chlorhexidine Digluconate Gingivitis Control Agent, Chlorhexidine Digluconate Dental Plaque Control Agent, Chlorhexidine Digluconate Veterinary Antiseptic, Chlorhexidine Digluconate Livestock Antiseptic, Chlorhexidine Digluconate Topical Antiseptic, Chlorhexidine Digluconate Topical Solution, Chlorhexidine Digluconate Hand Scrub Active, Chlorhexidine Digluconate Hand Wash Active, Chlorhexidine Digluconate Hygiene Agent, Chlorhexidine Digluconate Surface Disinfectant (application context), Chlorhexidine Digluconate Pharmaceutical Grade, Chlorhexidine Digluconate Medical Grade, Chlorhexidine Digluconate Active Ingredient, Chlorhexidine Digluconate API, Chlorhexidine Digluconate Active Antimicrobial, Chlorhexidine Digluconate Personal Care Antimicrobial, Chlorhexidine Digluconate Hygiene Ingredient, Chlorhexidine Digluconate Cosmetic Antimicrobial, Chlorhexidine Digluconate Controlled Release Agent (pharma context), Chlorhexidine Digluconate Antimicrobial Solution, Chlorhexidine Digluconate Aqueous Solution, Chlorhexidine Digluconate Concentrated Solution, Chlorhexidine Digluconate Dilution Concentrate, Chlorhexidine Digluconate Bulk Solution, Chlorhexidine Digluconate Raw Material, Chlorhexidine Digluconate Bulk Chemical, Chlorhexidine Digluconate Process Chemical, Chlorhexidine Digluconate Fine Chemical, Chlorhexidine Digluconate Specialty Chemical, Chlorhexidine Digluconate Industrial Biocide, Chlorhexidine Digluconate Infection Prevention Agent, Chlorhexidine Digluconate Anti-Infective Agent
APPLICATIONS
Chlorhexidine Digluconate is used in medical antiseptics.
Chlorhexidine Digluconate is applied for preoperative skin preparation and surgical hand scrubs.
Chlorhexidine Digluconate provides long-lasting antimicrobial protection on skin.
Chlorhexidine Digluconate is widely used in pharmaceutical formulations.
Chlorhexidine Digluconate is incorporated into topical solutions, sprays, and gels.
Chlorhexidine Digluconate supports infection control in hospitals and clinics.
Chlorhexidine Digluconate is used in dental and oral care products.
Chlorhexidine Digluconate is formulated into mouthwashes and dental gels.
Chlorhexidine Digluconate reduces plaque formation and gingivitis.
Chlorhexidine Digluconate is applied in cosmetic and personal care products.
Chlorhexidine Digluconate functions as an antimicrobial and preservative booster.
Chlorhexidine Digluconate improves microbiological stability of formulations.
Chlorhexidine Digluconate is used in veterinary medicine.
Chlorhexidine Digluconate is applied for animal skin disinfection and wound cleansing.
Chlorhexidine Digluconate ensures broad antimicrobial coverage.
Chlorhexidine Digluconate is employed in industrial disinfectants.
Chlorhexidine Digluconate is used for surface and equipment sanitation.
Chlorhexidine Digluconate maintains antimicrobial efficacy over time.
Chlorhexidine Digluconate is used as a broad-spectrum antiseptic in medical practice.
Chlorhexidine Digluconate reduces bacterial contamination on skin surfaces.
Chlorhexidine Digluconate is used in hospital disinfection protocols.
Chlorhexidine Digluconate helps prevent healthcare-associated infections.
Chlorhexidine Digluconate is used in preoperative skin preparation products.
Chlorhexidine Digluconate lowers the risk of surgical site infections.
Chlorhexidine Digluconate is used in wound cleansing solutions.
Chlorhexidine Digluconate supports infection control in acute and chronic wounds.
Chlorhexidine Digluconate is used in burn care formulations.
Chlorhexidine Digluconate reduces microbial growth on damaged skin.
Chlorhexidine Digluconate is used in oral hygiene products.
Chlorhexidine Digluconate reduces dental plaque formation.
Chlorhexidine Digluconate is used in medicated mouthwashes.
Chlorhexidine Digluconate supports management of gingivitis.
Chlorhexidine Digluconate is used in periodontal therapy.
Chlorhexidine Digluconate helps control oral bacterial populations.
Chlorhexidine Digluconate is used in dental surgery aftercare.
Chlorhexidine Digluconate reduces postoperative infection risk.
Chlorhexidine Digluconate is used in catheter site antiseptics.
Chlorhexidine Digluconate reduces microbial colonization on medical devices.
Chlorhexidine Digluconate is used in hand antiseptic products.
Chlorhexidine Digluconate provides persistent antimicrobial activity.
Chlorhexidine Digluconate is used in intensive care unit hygiene.
Chlorhexidine Digluconate supports infection prevention protocols.
Chlorhexidine Digluconate is used in veterinary antiseptic formulations.
Chlorhexidine Digluconate treats bacterial skin infections in animals.
Chlorhexidine Digluconate is used in animal wound care products.
Chlorhexidine Digluconate supports hygienic healing processes.
Chlorhexidine Digluconate is used in pharmaceutical antiseptic products.
Chlorhexidine Digluconate functions as an active antimicrobial ingredient.
Chlorhexidine Digluconate is used in cosmetic hygiene formulations.
Chlorhexidine Digluconate helps control microbial contamination.
Chlorhexidine Digluconate is used in personal care cleansing products.
Chlorhexidine Digluconate enhances microbial safety of formulations.
Chlorhexidine Digluconate is used in disinfectant sprays and wipes.
Chlorhexidine Digluconate provides long-lasting antimicrobial protection.
Chlorhexidine Digluconate is used in laboratory disinfection routines.
Chlorhexidine Digluconate supports aseptic working environments.
DESCRIPTION
Chlorhexidine Digluconate is a water-soluble salt of chlorhexidine.
Chlorhexidine Digluconate appears as a clear to pale yellow liquid.
Chlorhexidine Digluconate exhibits strong antimicrobial activity.
Chlorhexidine Digluconate is effective against Gram-positive bacteria.
Chlorhexidine Digluconate is effective against Gram-negative bacteria.
Chlorhexidine Digluconate shows limited activity against spores and some viruses.
Chlorhexidine Digluconate acts by disrupting microbial cell membranes.
Chlorhexidine Digluconate causes leakage of intracellular components.
Chlorhexidine Digluconate binds to skin and mucous membranes.
Chlorhexidine Digluconate provides prolonged residual antimicrobial action.
Chlorhexidine Digluconate is widely used in medical and dental fields.
Chlorhexidine Digluconate shows good stability in aqueous formulations.
Chlorhexidine Digluconate should be stored in tightly closed containers.
Chlorhexidine Digluconate should be protected from light and contamination.
Chlorhexidine Digluconate is valued for its effectiveness, persistence, and broad antimicrobial performance.
Chlorhexidine Digluconate is typically supplied as a clear to pale yellow aqueous solution.
Chlorhexidine Digluconate has a faint characteristic odor.
Chlorhexidine Digluconate is the digluconate salt of chlorhexidine, providing high water solubility.
Chlorhexidine Digluconate exhibits cationic behavior in solution.
Chlorhexidine Digluconate binds strongly to negatively charged surfaces such as skin and bacterial cell walls.
Chlorhexidine Digluconate disrupts microbial membranes, leading to leakage of intracellular components.
Chlorhexidine Digluconate demonstrates rapid bactericidal activity.
Chlorhexidine Digluconate provides prolonged residual antimicrobial action after application.
Chlorhexidine Digluconate shows low systemic absorption when used topically.
Chlorhexidine Digluconate is stable under recommended storage conditions.
Chlorhexidine Digluconate is incompatible with anionic surfactants and soaps.
Chlorhexidine Digluconate requires careful formulation to maintain activity.
PROPERTIES
Chemical Formula: C₂₂H₃₀Cl₂N₁₀ · 2C₆H₁₂O₇
Molecular Weight: ~897.76 g/mol
Appearance: Clear to pale yellow liquid (aqueous solution)
Odor: Faint characteristic odor
Physical Form: Typically supplied as 20% aqueous solution
Density: ~1.06 g/cm³ at 25°C (20% solution)
Melting Point: Not applicable (aqueous salt; decomposes before melting)
Boiling Point: Not applicable (aqueous solution)
Solubility in Water: Completely soluble
Solubility in Alcohols: Slightly soluble
Solubility in Nonpolar Solvents: Insoluble
pH (5% solution): ~5.0–7.0
Ionic Character: Cationic
Thermal Stability: Stable under normal storage temperatures
Antimicrobial Spectrum: Broad-spectrum antibacterial and antifungal
Residual Activity: High; binds to skin and mucous membranes
Chemical Stability: Stable in neutral to mildly acidic conditions
Incompatibilities: Anionic surfactants, soaps, strong oxidizing agents
Storage Stability: Good when protected from light and contamination
FIRST AID
Inhalation:
Move to fresh air if mist is inhaled.
Seek medical attention if irritation persists.
Skin Contact:
Generally safe for topical use.
Rinse with water if irritation occurs.
Eye Contact:
Rinse immediately with plenty of water for at least 15 minutes.
Seek medical attention promptly.
Ingestion:
Rinse mouth with water.
Do not induce vomiting.
Seek medical attention immediately.
Note to Physicians:
Treat symptomatically and provide supportive care.
HANDLING AND STORAGE
Handling:
Use protective gloves and eye protection.
Avoid contact with eyes and incompatible materials.
Avoidance:
Avoid mixing with anionic surfactants and soaps.
Avoid contamination during handling.
Spill Procedures:
Absorb with inert material and clean with water.
Dispose of according to local regulations.
Storage:
Store in tightly closed, properly labeled containers.
Keep in a cool, dry, well-ventilated area.
Protect from direct sunlight, freezing, and contamination.
