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CHLORHEXIDINE DIHYDROCHLORIDE

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Chlorhexidine Dihydrochloride is a member of guanidines.
Chlorhexidine Dihydrochloride is a bisbiguanide with bacteriostatic activity. 

CAS:    3697-42-5
MF:    C22H32Cl4N10
MW:    578.37
EINECS:    223-026-6

Synonyms
Chlorhexidine dihydrochloride >=98%;Chlorhexidini Hydrochloride;1,1’-hexamethylenebis(5-(p-chlorophenyl)-biguaniddihydrochloride;2,4,11,13-Tetraazatetradecanediimidamide;2,4,11,13-tetraazatetradecanediimidamide,n,n’’-bis(4-chlorophenyl)-3,12-diimin;2,4,11,13-Tetraazatetradecanediimidamide,N,N’’-bis(4-chlorophenyl)-3,12-diimino-,dihydrochloride;ArlacideH;Biguanide,1,1’-hexamethylenebis[5-(p-chlorophenyl)-,dihydrochloride

Chlorhexidine Dihydrochloride is a disinfectant that has been shown to be safe and effective for use in a wide variety of settings. 
Chlorhexidine Dihydrochloride is used as an antimicrobial agent in the medical, dental, and veterinary fields, as well as in food processing, water purification, and textile manufacturing. 
Chlorhexidine Dihydrochloride has been found to inhibit the growth of bacteria by disrupting the cell membrane or by inhibiting bacterial DNA synthesis. 
Chlorhexidine Dihydrochloride has also been shown to have anti-inflammatory properties.
Chlorhexidine Dihydrochloride is a orally active cationic antimicrobial agent that targets microbial cell membranes. 
Chlorhexidine Dihydrochloride binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. 
Chlorhexidine dihydrochloride has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. 
Chlorhexidine dihydrochloride can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis).
Chlorhexidine dihydrochloride is a orally active cationic antimicrobial agent that targets microbial cell membranes. 
Chlorhexidine dihydrochloride binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. 
Chlorhexidine dihydrochloride has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. 
Chlorhexidine dihydrochloride can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis).

Chlorhexidine hydrochloride Chemical Properties
Melting point: 111-116 °C
Density: 1.284[at 20℃]
Vapor pressure: 0.003Pa at 25℃
Storage temp.: 2-8°C
Solubility: Sparingly soluble in water and in propylene glycol, very slightly soluble in Ethanol (96 per cent).
Form: Solid
Color: White to Off-White
Odor: odorless
Water Solubility: 0.06 g/100 mL (20 ºC)
Merck: 14,2091
InChIKey: WJLVQTJZDCGNJN-UHFFFAOYSA-N
LogP: -1.94 at 22.2℃
EPA Substance Registry System: Chlorhexidine dihydrochloride (3697-42-5)

Uses    
Chlorhexidine Dihydrochloride is a preservative, it functions primarily as an anti-microbial, helping control the proliferation of bacteria, fungi, or yeast in a product.

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