CHONDROITIN SULFATE

Chondroitin Sulfate is a sulfated glycosaminoglycan used in dietary supplements, pharmaceuticals, nutraceuticals, cosmetics, veterinary products, and biomedical applications, and Chondroitin Sulfate is valued for its role in cartilage matrix structure, joint-support formulations, water-binding behavior, and biopolymer functionality.
Chondroitin Sulfate is commonly derived from animal cartilage sources such as bovine, porcine, avian, shark, or fish cartilage, and Chondroitin Sulfate quality depends on source, purity, sulfate pattern, molecular weight, protein content, ash content, moisture, microbiological quality, and regulatory grade.
Chondroitin Sulfate is typically supplied as a white to off-white hygroscopic powder, and Chondroitin Sulfate performance depends on assay, viscosity, particle size, sodium content, degree of sulfation, solubility, odor profile, heavy-metal limits, and compatibility with glucosamine, MSM, collagen, hyaluronic acid, minerals, and other actives.

CAS Number: 9007-28-7
EC Number: 232-696-9
Molecular Formula: Polymeric glycosaminoglycan; variable repeating disaccharide sulfate salt
Molecular Weight: Variable polymeric material, commonly grade dependent

Synonyms: Chondroitin Sulfate, Chondroitin Sulphate, Chondroitin Sulfate Sodium, Sodium Chondroitin Sulfate, Chondroitin Polysulfate, Chondroitin Sulfate A, Chondroitin Sulfate C, Sulfated Glycosaminoglycan, GAG Chondroitin Sulfate, Cartilage Extract Chondroitin Sulfate, Joint Support Chondroitin, Pharmaceutical Chondroitin Sulfate, Chondroitin Sulfate, Chondroitin Sulphate, Chondroitin Sulfate Sodium, Sodium Chondroitin Sulfate, Chondroitin Sulfate Sodium Salt, Chondroitin Sulphate Sodium Salt, Chondroitin Sodium Sulfate, Chondroitin Sodium Sulphate, Chondroitin Sulfate A, Chondroitin Sulfate C, Chondroitin-4-Sulfate, Chondroitin-6-Sulfate, Chondroitin 4-Sulfate, Chondroitin 6-Sulfate, Chondroitin Polysulfate, Sulfated Chondroitin, Chondroitin Sulfated Glycosaminoglycan, Chondroitin Glycosaminoglycan, GAG Chondroitin Sulfate, Mucopolysaccharide Chondroitin Sulfate, Chondroitin Sulfate Proteoglycan Component, Chondroitin Sulfate Cartilage Extract, Cartilage Chondroitin Sulfate, Shark Cartilage Chondroitin Sulfate, Bovine Chondroitin Sulfate, Marine Chondroitin Sulfate, Chondroitin Sulfate Powder, Chondroitin Sulfate Granules, Chondroitin Sulfate Solid, Chondroitin Sulfate Pharmaceutical Grade, Chondroitin Sulfate Food Grade, Chondroitin Sulfate Nutraceutical Grade, Chondroitin Sulfate Cosmetic Grade, Chondroitin Sulfate Technical Grade, Chondroitin Sulfate High Purity, High Purity Chondroitin Sulfate, Chondroitin Sulfate Pure, Pure Chondroitin Sulfate, Chondroitin Sulfate Joint Health Ingredient, Chondroitin Sulfate Dietary Supplement, Chondroitin Sulfate Cartilage Support, Chondroitin Sulfate CAS 9007-28-7, Sodium Chondroitin Sulfate CAS 9082-07-9, Chondroitin Sulfate Sodium CAS 9082-07-9, Chondroitin Sulfate Commercial Grade, Commercial Chondroitin Sulfate

APPLICATIONS

Chondroitin Sulfate is used in dietary supplements for joint-support formulations.
Chondroitin Sulfate is incorporated into tablets, capsules, powders, sachets, gummies, and liquid supplements where cartilage-support positioning is desired.
Chondroitin Sulfate is often combined with glucosamine, MSM, collagen, hyaluronic acid, vitamin C, manganese, or botanical extracts in joint-health products.

Chondroitin Sulfate is used in pharmaceutical and nutraceutical products where purified glycosaminoglycan functionality is required.
Chondroitin Sulfate is incorporated into regulated oral products depending on local classification as a drug, food supplement, or nutraceutical ingredient.
Chondroitin Sulfate is used in product systems where assay, source traceability, molecular weight, and impurity control are important quality parameters.

Chondroitin Sulfate is used in veterinary joint-support products for companion animals, horses, and livestock-related applications.
Chondroitin Sulfate is incorporated into veterinary tablets, chews, powders, pastes, and liquid formulas for mobility-support positioning.
Chondroitin Sulfate is used with glucosamine, MSM, omega fatty acids, collagen, and hyaluronic acid in animal-care formulations.

Chondroitin Sulfate is used in cosmetic and personal care formulations as a moisturizing, conditioning, and film-forming biopolymer.
Chondroitin Sulfate is incorporated into creams, serums, masks, lotions, and anti-aging products where water-binding and skin-feel properties are useful.
Chondroitin Sulfate is used in topical formulations where polysaccharide functionality supports hydration, softness, and surface conditioning.

Chondroitin Sulfate is used in biomedical research, tissue engineering, ophthalmic research, and biomaterial systems because it is a natural glycosaminoglycan associated with extracellular matrix structure.
Chondroitin Sulfate is incorporated into hydrogels, scaffolds, drug-delivery research systems, and cell-culture-related materials depending on grade and regulatory suitability.
Chondroitin Sulfate is valued because Chondroitin Sulfate provides sulfated polysaccharide functionality, water-binding capacity, joint-support positioning, matrix-related biological relevance, and broad usefulness in supplements, pharmaceuticals, cosmetics, veterinary products, and biomedical materials.

Chondroitin Sulfate is used in dietary supplements designed to support joint health and mobility.
Chondroitin Sulfate is used in formulations intended to maintain the structural integrity of cartilage.
Chondroitin Sulfate is used in combination with glucosamine in many joint-support products.
Chondroitin Sulfate is used in capsules, tablets, powders, and liquid supplement formats.

Chondroitin Sulfate is used in sports nutrition products for individuals exposed to repetitive joint stress.
Chondroitin Sulfate is used in healthy-aging supplements focused on mobility and physical comfort.
Chondroitin Sulfate is used in products intended to support active lifestyles.
Chondroitin Sulfate is used in daily nutritional programs for long-term joint maintenance.

Chondroitin Sulfate is used in veterinary supplements intended to support joint function in dogs.
Chondroitin Sulfate is used in equine products formulated for cartilage and mobility support.
Chondroitin Sulfate is used in companion-animal supplements combined with glucosamine and methylsulfonylmethane.
Chondroitin Sulfate is used in veterinary chewable tablets, powders, and feed supplements.

Chondroitin Sulfate is used in pharmaceutical research involving cartilage metabolism.
Chondroitin Sulfate is used in studies examining the composition of extracellular matrices.
Chondroitin Sulfate is used in laboratory investigations of connective-tissue structure.
Chondroitin Sulfate is used in biochemical studies involving glycosaminoglycan function.

Chondroitin Sulfate is used in cell-culture research to investigate cartilage-cell behavior.
Chondroitin Sulfate is used in studies of chondrocyte growth and matrix production.
Chondroitin Sulfate is used in experimental systems designed to model cartilage degradation.
Chondroitin Sulfate is used in research on inflammatory signaling within connective tissues.

Chondroitin Sulfate is used in tissue-engineering scaffolds intended to mimic cartilage environments.
Chondroitin Sulfate is used in biomaterials designed to support cell attachment and matrix formation.
Chondroitin Sulfate is used in hydrogel systems for regenerative-medicine research.
Chondroitin Sulfate is used in composite materials containing collagen, gelatin, or hyaluronic acid.

Chondroitin Sulfate is used in wound-care research because of its water-binding and matrix-related properties.
Chondroitin Sulfate is used in experimental dressings designed to maintain a hydrated environment.
Chondroitin Sulfate is used in biomaterial coatings intended to improve biological compatibility.
Chondroitin Sulfate is used in controlled-release research for selected active ingredients.

Chondroitin Sulfate is used in ophthalmic research involving corneal and ocular tissues.
Chondroitin Sulfate is used in selected eye-care formulations as a lubricating or protective polymer component.
Chondroitin Sulfate is used in experimental artificial-tear systems to improve surface hydration.
Chondroitin Sulfate is used in studies of glycosaminoglycans present in ocular structures.

Chondroitin Sulfate is used in cosmetic formulations intended to improve skin hydration.
Chondroitin Sulfate is used in anti-aging products as a moisture-binding ingredient.
Chondroitin Sulfate is used in creams and serums designed to support a smooth skin feel.
Chondroitin Sulfate is used in facial masks and hydrogels requiring water-retention properties.

Chondroitin Sulfate is used in hair-care research as a conditioning biopolymer.
Chondroitin Sulfate is used in scalp-care products where hydration support is desired.
Chondroitin Sulfate is used in cosmetic emulsions as a functional polysaccharide ingredient.
Chondroitin Sulfate is used in specialty personal-care products focused on biomimetic formulation concepts.

Chondroitin Sulfate is used as an analytical reference material in glycosaminoglycan testing.
Chondroitin Sulfate is used in chromatography method development for purity and identity analysis.
Chondroitin Sulfate is used in electrophoresis and spectroscopy studies of sulfated polysaccharides.
Chondroitin Sulfate is used in quality-control laboratories to verify molecular composition and sulfate content.

Chondroitin Sulfate is used in raw-material testing to confirm species source and authenticity.
Chondroitin Sulfate is used in screening programs designed to detect adulteration or substitution.
Chondroitin Sulfate is used in product-development trials to optimize solubility, taste, and dosage form.
Chondroitin Sulfate is used in stability studies to monitor moisture uptake and molecular degradation.

Chondroitin Sulfate is used in nutraceutical manufacturing where a standardized glycosaminoglycan ingredient is required.
Chondroitin Sulfate is used in quality control to evaluate identity, purity, moisture, microbiological quality, and assay.

Chondroitin Sulfate is soluble or dispersible in water depending on molecular weight and purity.
Chondroitin Sulfate forms viscous aqueous solutions at suitable concentrations.
Chondroitin Sulfate has strong water-binding properties because of its ionic and hydrophilic structure.
Chondroitin Sulfate contributes to the hydration and resilience of cartilage tissue.

Chondroitin Sulfate occurs in several structural forms that differ according to sulfate position.
Chondroitin Sulfate A is predominantly sulfated at the 4-position of N-acetylgalactosamine.
Chondroitin Sulfate C is predominantly sulfated at the 6-position of N-acetylgalactosamine.
Chondroitin Sulfate composition can vary according to biological source and processing method.

Chondroitin Sulfate quality is commonly evaluated by assay, molecular weight, sulfate content, and impurity profile.
Chondroitin Sulfate identity may be assessed using chromatography, electrophoresis, spectroscopy, or enzymatic methods.
Chondroitin Sulfate purity is important because structurally related glycosaminoglycans may occur as contaminants.
Chondroitin Sulfate commercial grades may differ in viscosity, particle size, odor, and color.

Chondroitin Sulfate is widely used in nutraceutical, veterinary, pharmaceutical, cosmetic, and biomedical research applications.
Chondroitin Sulfate performance depends on molecular size, degree of sulfation, source, and formulation conditions.
Chondroitin Sulfate should be protected from excessive moisture, heat, and microbial contamination.
Chondroitin Sulfate should be stored in tightly closed packaging under cool and dry conditions.

Chondroitin Sulfate is valued for its cartilage-related biological role, water-binding capacity, and broad usefulness in health and biomaterial products.

DESCRIPTION

Chondroitin Sulfate is a naturally occurring sulfated glycosaminoglycan found in connective tissues.
Chondroitin Sulfate is an important structural component of cartilage and extracellular matrix.
Chondroitin Sulfate consists of repeating disaccharide units containing glucuronic acid and N-acetylgalactosamine.
Chondroitin Sulfate contains sulfate groups that give the molecule a strong negative charge.

Chondroitin Sulfate is commonly obtained from bovine, porcine, avian, or marine cartilage sources.
Chondroitin Sulfate may also be produced through controlled biotechnological or fermentation-based processes.
Chondroitin Sulfate is generally supplied as a white to off-white hygroscopic powder.
Chondroitin Sulfate is commonly marketed in the form of sodium chondroitin sulfate.

Chondroitin Sulfate is a sulfated glycosaminoglycan composed of repeating disaccharide units containing an amino sugar and a uronic acid unit.
Chondroitin Sulfate occurs naturally in cartilage, connective tissue, tendons, ligaments, and other extracellular matrix structures.
Chondroitin Sulfate is usually commercialized as the sodium salt because this form provides practical water solubility, powder handling, and formulation compatibility.

Chondroitin Sulfate is not a single uniform molecule, and commercial grades differ by animal source, molecular weight distribution, sulfate position, purity, and manufacturing process.
Chondroitin Sulfate A is commonly associated with 4-sulfated disaccharide units, while Chondroitin Sulfate C is commonly associated with 6-sulfated disaccharide units.
Chondroitin Sulfate identity and quality should be verified by suitable analytical methods because adulteration, source variation, and inconsistent assay can affect finished-product quality.

Chondroitin Sulfate is highly hydrophilic and can bind water, which supports its use in joint-support, moisturizing, and biomaterial applications.
Chondroitin Sulfate may be sensitive to strong acids, strong bases, oxidizers, high heat, and microbial contamination, so careful handling and storage are important.
Chondroitin Sulfate should be used according to supplier specifications, food supplement regulations, pharmaceutical standards, cosmetic regulations, veterinary requirements, allergen declarations, and source traceability expectations.

PROPERTIES

CAS Number: 9007-28-7
EC Number: 232-696-9
Common Name: Chondroitin Sulfate
Chemical Type: Sulfated glycosaminoglycan; sulfated polysaccharide; biopolymer; sodium salt grade common
Appearance: White to off-white powder
Odor: Odorless to mild characteristic animal-derived odor, grade dependent
Taste: Slightly salty or characteristic, grade dependent
Solubility: Soluble or dispersible in water; insoluble in most nonpolar organic solvents
Ionic Character: Anionic polysaccharide due to sulfate and carboxylate groups
Molecular Weight: Variable, grade dependent
Assay: Grade dependent
Sulfate Pattern: 4-sulfated, 6-sulfated, or mixed pattern, source and grade dependent
Source: Bovine, porcine, avian, shark, fish, or other cartilage source, supplier dependent
Function: Joint-support ingredient, glycosaminoglycan, moisturizing agent, conditioning polymer, biomedical material component
Compatibility: Compatible with many aqueous supplement, cosmetic, veterinary, and biomedical systems; compatibility depends on pH, salts, preservatives, and other polymers
Hygroscopicity: May absorb moisture under humid conditions
Stability: Stable under recommended dry storage; protect from moisture, heat, oxidation, and contamination
Storage Temperature: 15–25°C, tightly closed, dry, protected from light and humidity
Shelf Life: Typically 24–36 months in original sealed packaging, supplier dependent

FIRST AID

Inhalation:
Move to fresh air if powder dust is inhaled.
Seek medical attention if coughing, respiratory irritation, allergy-like symptoms, or breathing discomfort persists.
Avoid breathing dust during weighing, blending, milling, and powder transfer operations.

Skin Contact:
Wash skin with soap and water after contact.
Seek medical advice if irritation, redness, itching, or allergic reaction develops.
Remove contaminated clothing if necessary and wash before reuse.

Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation, redness, or foreign-body sensation persists.

Ingestion:
Rinse mouth with water.
Seek medical attention if discomfort occurs or if a significant non-food-grade amount is swallowed.
Do not use industrial or research grade material for consumption.

Note to Physicians:
Treat symptomatically.
Monitor for irritation, gastrointestinal discomfort, or allergic response after significant exposure.
Consider source-related sensitivity in individuals with allergies to animal, marine, bovine, porcine, fish, or shellfish-associated materials.

HANDLING AND STORAGE

Handling:
Use appropriate PPE including gloves, safety glasses, protective clothing, and dust protection where bulk powder exposure may occur.
Avoid generating dust during weighing, charging, blending, milling, and packaging operations.
Use clean, dry equipment to prevent contamination and maintain food, pharmaceutical, cosmetic, or veterinary grade quality.

Ventilation:
Use general ventilation for normal handling.
Use local exhaust ventilation where powder dust may be generated.
Avoid inhalation exposure during bulk powder transfer and high-speed blending.

Storage:
Store in tightly closed containers in a cool, dry, well-ventilated area.
Protect from moisture, excessive heat, direct sunlight, and microbial contamination.
Keep away from strong oxidizers, strong acids, strong bases, and incompatible reactive chemicals.

Spill and Leak Procedures:
Avoid dust generation and collect spilled powder using vacuum or careful sweeping methods.
Place material into suitable containers for reuse or disposal according to quality status and local regulations.
Clean remaining residue with water if allowed by facility procedure because polysaccharide residues can become slippery when wet.

Handling Precautions:
Verify source and grade because Chondroitin Sulfate regulatory status, allergen labeling, religious suitability, and market acceptance depend on animal origin and manufacturing controls.
Control moisture because Chondroitin Sulfate is hydrophilic and may cake, lose flowability, or support microbial risk if exposed to humidity.
Rotate stock using FIFO practices to maintain consistent assay, color, odor, moisture, solubility, molecular weight profile, and finished-product performance.