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Cithrol PGMIS is a 1-monoglyceride with tetradecanoyl (myristoyl) as the acyl group.
Cithrol PGMIS has a role as a Caenorhabditis elegans metabolite.
Cithrol PGMIS allows the formulation of clear facial cleansers comprising oil and water in a microemulsion, maintaining the perfect hydro-lipophilic balance.
CAS Number: 27214-38-6
Molecular Formula: C17H34O4
Molecular Weight: 302.45
EINECS Number: 248-329-0
Synonyms: Monomyristin, 589-68-4, 2,3-Dihydroxypropyl tetradecanoate, 1-Monomyristin, 1-Myristoyl-rac-glycerol, Glycerol 1-myristate, Glyceryl monomyristate, 27214-38-6, Myristin, 1-mono-, Glyceryl myristate, .alpha.-Monomyristin, Glycerol monomyristate, Myristic acid 1-monoglyceride, rac-1-Myristoylglycerol, Tetradecanoic acid, 2,3-dihydroxypropyl ester, DL-alpha-Myristin, (+/-)-2,3-Dihydroxypropyl tetradecanoate, 1-monomyristoylglycerol, rac-Glycerol 1-myristate, Tetradecanoic acid, monoester with 1,2,3-propanetriol, SMJ2192F1R, DTXSID0042454, CHEBI:75567, NSC-404225, 2,3-Dihydroxypropyl myristate, Glycerol, monomyristate, 1-MONOMYRISTOYL-rac-GLYCEROL, UNII-SMJ2192F1R, Monomyristin?, 1-Moristristin, 1-Monotetradecanoyl-rac-glycerol, Tetradecanoic acid, monoglyceride, MG 14:0, DL--Myristin, EINECS 248-329-0, 1-myristoyl glycerol, UNII-6992Y81827, 1-tetradecanoylglycerol, rac-tetradecanoylglycerol, 1-Monomyristoyl Glycerol, AI3-03491, 2,3-dihydroxypropyl ester, rac-1-monomyristoylglycerol, Glycerol alpha-Monomyristate, GLYCERYL 1-MYRISTATE, SCHEMBL62800, CHEMBL463092, Glycerol .alpha.-tetradecanoate, DTXCID1022005, RAC-GLYCEROL-1-MYRISTATE, CHEBI:75562, HY-N2512, MAG 14:0, rac-Glycerol 1-myristate, >=99%, GLYCEROL 1-MONOTETRADECANOATE, Tox21_301507, 1,2,3-Propanetriol 1-teradecanoate, MFCD00046760, NSC404225, s5829, GLYCEROL .ALPHA.-MONOMYRISTATE, AKOS015951205, rac-2,3-dihydroxypropyl tetradecanoate, NSC 404225, NCGC00255819-01, NCGC00414904-01, AC-34680, AS-61762, CAS-589-68-4, DA-65604, Tetradecanoic acid, 3-dihydroxypropyl ester, MYRISTIC ACID .ALPHA.-MONOGLYCERIDE, CS-0022783, M1073, NS00013705, TETRADECANOIC ACID .ALPHA.-MONOGLYCERIDE, A869310, W-110695, Q60998700, 6992Y81827, Tetradecanoicacid,monoesterwith1,2,3-propanetriol,Tetradecanoicacid,monoglyceride,TETRADECANOIN,RAC-GLYCEROL 1-MYRISTATE,RAC-1-MYRISTOYLGLYCEROL,MONOMYRISTIN,1-MYRISTOYL-RAC-GLYCEROL,1-MONOTETRADECANOYL-RAC-GLYCEROL
Cithrol PGMIS is a substantive emollient suitable for hydroalcoholic formulations.
Cithrol PGMIS is a non-ionic polyol ester surfactant and emulsifier.
It is derived from plant and petrochemicals.
Cithrol PGMIS is free from preservative, BHT/BHA and EDTA.
Cithrol PGMIS maintains the perfect hydro-lipophilic balance to easily cleanse dirt and make-up from the skin.
It creates advanced, high-performance microemulsion facial cleansers that are crystal clear, gentle to skin and easily rinsed leaving no oily residue.
Cithrol PGMIS is very mild to skin and can also be used to create gentle and effective surfactant oil cleansers, cleansing oils that emulsify on contact with water so they can be rinsed from skin on application of water.
The microemulsion and oil cleansers are very efficient at removing long wear and water proof make-up while leaving the skin feeling renewed, smooth and soft to the touch.
Cithrol PGMIS is a 1-monoglyceride and a tetradecanoate ester.
Cithrol PGMIS is used in facial cleansers, bath, shower and soaps products.
It is Vegan suitable and Halal certified.
Cithrol PGMIS functions predominantly as a co-emulsifier but can also be added as a very substantive emollient.
Cithrol PGMIS is a specialized emulsifier, primarily used in cosmetic and personal care formulations.
It is a non-ionic surfactant derived from natural sources and is particularly valued for its ability to stabilize oil-in-water emulsions.
Cithrol PGMIS helps to blend water and oil phases, providing a stable mixture in creams, lotions, and other emulsified products.
Cithrol PGMIS often imparts moisturizing properties to formulations, making it suitable for skin and hair care products.
Being a non-ionic surfactant, it is generally milder compared to ionic surfactants, making it suitable for sensitive skin formulations.
Cithrol PGMIS is primarily composed of polyglycerol esters of fatty acids, with the polyglycerol portion providing it with emulsifying properties.
The specific CAS number may vary depending on the supplier or manufacturer.
Cithrol PGMIS has a moderate HLB value, which indicates its effectiveness as an emulsifier in stabilizing oil-in-water emulsions.
It is typically soluble in both aqueous and organic phases, which enhances its versatility in formulation.
Cithrol PGMIS is used in facial and body creams for hydrating and conditioning effects.
Helps to stabilize the formulation and improve the application of sunscreen products.
Found in foundations and primers for a smooth application.
Cithrol PGMIS is used in conditioners and styling products to improve texture and manageability.
Enhances the performance of cleansing products by providing a rich, creamy texture.
Cithrol PGMIS utilized in topical drug formulations to enhance the delivery of active ingredients.
Improves the shelf life of emulsions by preventing separation of oil and water phases.
Contributes to a pleasant skin feel and improves the spreadability of products.
Cithrol PGMISs non-ionic nature makes it suitable for sensitive skin and reduces the risk of irritation.
Generally regarded as safe for use in cosmetic formulations.
However, like any ingredient, it should be tested for compatibility and irritation potential based on the final formulation.
Approved for use in cosmetics by various regulatory agencies, although it's always good to check for specific regional regulations.
Cithrol PGMIS is compatible with a wide range of cosmetic ingredients, including oils, waxes, and other emulsifiers.
This makes it a versatile choice in formulation development.
Melting point: 68-70 °C
Density: 0.929[at 20℃]
storage temp.: −20°C
Odor: at 100.00?%. bland
Dielectric constant: 6.1（70℃）
LogP: 5.048 (est)
Cithrol PGMIS can be added to the oil phase of emulsions.
It effectively reduces the surface tension between oil and water, facilitating the formation of stable emulsions.
Cithrol PGMIS can also be incorporated during the cooling phase of hot emulsions to preserve its functional properties.
The typical concentration for Cithrol PGMIS in formulations ranges from 1% to 5%, depending on the desired viscosity, stability, and emulsification requirements.
Combining Cithrol PGMIS with other emulsifiers or stabilizers can enhance formulation stability and texture.
For instance, pairing with natural gums or thickeners can improve the overall product feel.
There is a growing demand for natural and biodegradable ingredients in the cosmetic industry.
Cithrol PGMIS, derived from natural sources, aligns with this trend and appeals to environmentally conscious consumers.
As consumers seek transparency and safety in their products, the use of non-toxic and mild emulsifiers like Cithrol PGMIS has gained traction.
The versatility of Cithrol PGMIS allows for its incorporation into a wide range of products, from high-end cosmetics to everyday personal care items, thus expanding its market potential.
While primarily known for cosmetic uses, polyglycerol esters, including those like Cithrol PGMIS, may also find applications in food products as emulsifiers, stabilizers, or texturizers.
Cithrol PGMIS can be employed in formulations requiring controlled release of active ingredients, enhancing bioavailability and therapeutic effects.
In some cases, it may be used in industrial formulations, such as lubricants or coatings, owing to its emulsifying properties.
Enhances the sensory profile of formulations, contributing to a creamy texture and smooth application, which can enhance consumer satisfaction.
Cithrol PGMIS can improve the stability and effectiveness of various active ingredients, such as vitamins and botanical extracts, in formulations.
Compared to traditional emulsifiers, it can help formulate lighter creams and lotions that feel less greasy, catering to consumer preferences for lightweight products.
While generally safe, formulations containing Cithrol PGMIS should undergo dermatological testing to confirm skin compatibility, especially for sensitive skin formulations.
As a biodegradable surfactant, Cithrol PGMIS has a lower environmental impact compared to synthetic surfactants, making it a preferable choice in eco-friendly formulations.
Uses:
Cithrol PGMIS helps stabilize oil-in-water (O/W) emulsions, ensuring that oils and water mix effectively in creams, lotions, and serums.
This property enhances the texture and consistency of products.
As a mild surfactant, it aids in the formulation of cleansers, shampoos, and body washes, contributing to foaming properties while being gentle on the skin.
Cithrol PGMIS helps maintain the stability of formulations over time, preventing separation and enhancing shelf life.
It can increase the viscosity of formulations, providing a desirable texture in creams, lotions, and gels.
Cithrol PGMIS contributes to skin conditioning, helping to improve the skin's hydration and overall feel.
It can act as a carrier for active ingredients, helping to improve their absorption and effectiveness in topical applications.
Though primarily used in cosmetics, polyglycerol esters like Cithrol PGMIS can be used as emulsifiers and stabilizers in food products, aiding in texture and consistency.
Cithrol PGMIS may be included in pharmaceutical products as an emulsifier or stabilizer for topical creams and ointments.
Used in foundations, primers, and other cosmetic products to improve texture and application.
Helps to create stable formulations that ensure even distribution and effectiveness of active sunscreen ingredients.
Occasionally found in formulations for household cleaning products or fabric care due to its emulsifying properties.
Cithrol PGMIS is generally regarded as safe for use in cosmetic formulations.
Cithrol PGMIS is biodegradable, making it an environmentally friendly choice.
Cithrol PGMIS is often used in formulations for sensitive skin due to its gentle nature, reducing the likelihood of irritation.
This emulsifier is compatible with a wide range of surfactants and other ingredients, enhancing its versatility in different formulations.
Apart from its emulsifying properties, Cithrol PGMIS may also impart moisturizing benefits, enhancing the overall performance of the product.
It provides a smooth and creamy texture to products, which is particularly desirable in lotions, creams, and gels.
Typical usage levels for Cithrol PGMIS in emulsions range from 1% to 5%, but this may vary depending on the specific formulation and desired properties.
It maintains effectiveness across a range of temperatures, making it suitable for products that may undergo heat during processing or storage.
Cithrol PGMIS is stable across a broad pH range, allowing it to be used in various formulations, including those designed for sensitive skin.
When using Cithrol PGMIS, it is typically added to the oil phase of emulsions during the heating phase, followed by emulsification with the aqueous phase.
Cithrol PGMIS has undergone safety evaluations and is considered safe for use in cosmetics and personal care products, as per regulatory guidelines from bodies such as the Cosmetic Ingredient Review (CIR) and the European Commission.
The International Nomenclature of Cosmetic Ingredients (INCI) name for Cithrol PGMIS is "Polyglycerol Myristate," which is important for labeling on cosmetic products.
In the European Union, it complies with regulations under the Cosmetic Products Regulation (EC) No 1223/2009.
Cithrol PGMIS is important to check specific regulations if used in food or pharmaceuticals, as these may vary.
Its biodegradable nature aligns with growing consumer demand for sustainable and environmentally friendly products.
Used in moisturizers, anti-aging creams, and serums to enhance texture and emulsion stability.
Found in shampoos, conditioners, and styling products to improve application and enhance the feel of the hair.
Incorporated into foundations, primers, and lip products for smooth application and improved wear.
Helps in forming stable emulsions for sun protection products, ensuring even distribution of active ingredients.
Cithrol PGMIS is used in body lotions, creams, and oils for its moisturizing and emulsifying properties.
May be utilized in topical formulations for its emulsifying and skin-conditioning properties.
Safety Profile:
While Cithrol PGMIS is generally mild and well-tolerated, some individuals may experience skin irritation, particularly if they have sensitive skin or allergies to similar compounds.
There is a possibility of allergic reactions in susceptible individuals, though such reactions are rare.
It is advisable for consumers with known allergies to perform a patch test before using products containing this ingredient.
Direct contact with the eyes may cause irritation.
Formulators should ensure that products are designed to minimize the risk of eye exposure.
In powdered form or as an aerosol, inhalation of any particulate matter could lead to respiratory irritation, although this is more relevant for large-scale manufacturing or improper handling.
While Cithrol PGMIS is biodegradable and generally considered environmentally friendly, improper disposal of products containing this ingredient could contribute to environmental pollution.
Following the recommended usage levels (typically 1% to 5% in formulations) can minimize potential risks.
Consumers should conduct a patch test before widespread use, especially if they have sensitive skin or a history of allergic reactions.
Ensure that products comply with local regulations and safety assessments, as regulatory bodies often review safety data to confirm the suitability of cosmetic ingredients.
Manufacturers should follow good manufacturing practices (GMP) and safety protocols when handling and formulating products with Cithrol PGMIS to minimize any potential hazards.
