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CRODAMOL EO


CAS NO:111-62-6
EC NO:203-889-5

Excellent solvent and good moisturiser. Suitable for skin care, hair care and colour cosmetics.

Physical form at 25°C
Liquid

Chemistry
Emollient esters & ethers

Functions
Solvents
Spreading agents

Applications
Bath, shower & soaps
Antiperspirants & deodorants
Body care
Face / neck skin care
Face colour
Hair colour
Hair conditioners - rinse off
Shampoos
Shaving / hair removal
Styling
Sun protection

Consumer benefit
Gloss / shine / vibrancy

Crodamol EO is Ethyl Oleate and conforms to both the National Formulary (NF) and European Pharmacopoeia (EP) monographs. 
Crodamol EO is the ester of ethanol and oleic acid (C18:1). 
Crodamol EO derived from raw materials of non-animal origin, exhibits excellent color profile, low viscosity, and is a good spreading agent.  
Crodamol EO is an excellent solvent and good moisturizer, suitable for use in multiple skin care, hair care and color cosmetic applications.

Low viscosity solvent for lipophilic actives. Non-occlusive emollient with good spreading properties. Rapidly absorbed by body tissues. Dermal penetration enhancer. Required HLB value of 11. Recommended topical usage levels of 0.5-5%.

Crodamol EO by Croda acts as an emollient, spreading agent, moisturiser and solvent. 
Crodamol EO imparts gloss, shine and vibrancy. 
Crodamol EO is preservative free and readily biodegradable. 
Crodamol EO is used in skin care, hair styling, rinse off conditioners, hair coloring, shaving/ hair removal, body care, antiperspirants/deodorants, face/ neck skin care, eye color and sun protection formulations.

Properties:     
Molecular Formula:    C20H38O2
Molecular weight:    310,51

Crodamol EO is a fatty acid ester formed by the condensation of oleic acid and ethanol. 
Crodamol EO is a colorless oil although degraded samples can appear yellow.
Crodamol EO is used by compounding pharmacies as a vehicle for intramuscular drug delivery, in some cases to prepare the daily doses of progesterone in support of pregnancy.

Properties
Chemical formula    C20H38O2
Molar mass    310.522 g·mol−1
Appearance    Colorless to light yellow liquid[1]
Density    0.87 g/cm3[1]
Melting point    −32 °C (−26 °F; 241 K)[1]
Boiling point    216–218 °C (421–424 °F; 489–491 K)[1] (15 hPa)
Solubility in water    Insoluble[1]

Crodamol EO is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of oleic acid with the hydroxy group of ethanol. 
Crodamol EO has a role as a plant metabolite and an acaricide. 
Crodamol EO derives from an oleic acid.

Crodamol EO is a natural product found in Aristolochia fontanesii, Portulaca oleracea, and other organisms with data available.

Industry Uses    
Lubricants and lubricant additives
Plating agents and surface treating agents

Industry Processing Sectors
Paint and coating manufacturing
Petroleum lubricating oil and grease manufacturing

Formula: C20H38O2
Molecular weight: 310.5145

Crodamol EO, also known as ethyl oleic acid, belongs to the class of organic compounds known as fatty acid esters. These are carboxylic ester derivatives of a fatty acid. Based on a literature review a small amount of articles have been published on Crodamol EO.

Crodamol EO (Oleic acid ethyl ester) is a fatty acid ester formed by the condensation of oleic acid and ethanol, usually used as a solvent for pharmaceutical drug preparations.
Density    0.87 g/mL at 25 °C

Crodamol EO is the ester formed by the condensation of the fatty acid oleic acid and ethanol. 
Crodamol EO is a colorless to light yellow liquid. 
Crodamol EO is produced by the body during ethanol intoxication

Crodamol EO is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids.
Crodamol EO also finds use as a lubricant and a plasticizer.
Crodamol EO has been identified as a primer pheromone in honeybees.

Crodamol EO is a fatty acid ester formed by the condensation of oleic acid and ethanol. 
Crodamol EO is a colorless to light yellow liquid. 

Crodamol EO is a fatty acid ester used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids. 

Crodamol EO and other fatty acid esters are also rapidly hydrolyzed to ethanol and free fatty acid. 
Crodamol EO is one of the fatty acid ethyl esters (FAEE) that is formed in the body after ingestion of ethanol. 

Crodamol EO is a fatty acid ester formed by the condensation of oleic acid and ethanol. 
Crodamol EO is the liquid lipid component in nanostructured lipid carriers (NLCs).

Crodamol EO was obtained by the hydrolysis of various animal and vegetable fats and oils.

Appearance :Oil
Physical State :Liquid
Solubility :Soluble in Benzene, Chloroform and DMSO
Storage :Store at -20° C

Crodamol EO is a colorless to light yellow liquid, fatty acid ester that occurs from the condensation of ethanol and oleic acid.

Crodamol EO is a fatty acid ester formed by the condensation of oleic acid and ethanol. 
Crodamol EO is a colorless to light yellow liquid. 
Crodamol EO is produced by the body during ethanol intoxication.

Crodamol EO is a fatty acid ester formed by the condensation of oleic acid and ethanol. 
Crodamol EO is a colorless to pale yellow liquid. 
Crodamol EO is produced by the body during ethanol poisoning.

Crodamol EO is used as a solvent for pharmaceutical preparations containing lipophilic substances such as steroids. 
Crodamol EO is also used as a lubricant and a plasticizer.

Crodamol EO has been identified as a primer pheromone in honey bees.

Pharmaceutical Industry
Crodamol EO is utilized as an ingredient for the preparations of pharmaceutical drugs that involves lipophilic substances such as steroids. Due to its quick degradation of the digestive system, Crodamol EO is employed as a way for intramuscular drug delivery by compounding pharmacies. In some cases, the compound is used in the preparation of day-to-day doses of progesterone in the sustenance of pregnancy.

Transport Industry
Crodamol EO is used in the transport industry as a lubricant and as a plasticiser. 
Crodamol EO is also used as a planting agent and for treating surfaces.

Food Industry
Crodamol EO is used as a food additive and is regulated by the Food and Drug Administration. 
Crodamol EO is also used as a flavouring agent in food.

Description    
Crodamol EO is a fatty acid ester formed by the condensation of oleic acid and ethanol. 
Crodamol EO is a colorless to light yellow liquid. 
Crodamol EO is produced by the body during ethanol intoxication.
Crodamol EO is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids. 
Crodamol EO also finds use as a lubricant and a plasticizer.
Crodamol EO has been identified as a primer pheromone in honeybees.

Chemical Properties    
Ethyl oleate has a faint, floral note.

Chemical Properties    
clear pale yellow oily liquid

Chemical Properties    
Crodamol EO occurs as a pale yellow to almost colorless, mobile, oily liquid with a taste resembling that of olive oil and a slight, but not rancid odor.
Crodamol EO is described in the USP32–NF27 as consisting of esters of ethyl alcohol and high molecular weight fatty acids, principally oleic acid. A suitable antioxidant may be included.

Uses    
Crodamol EO is a flavoring and fragrance agent.

Uses    
Crodamol EO was obtained by the hydrolysis of various animal and vegetable fats and oils.

Uses    
Usually used to prepare the oily phase of self-microemulsifying drug delivery system (SMEDDS) for tacrolimus (Tac).

Crodamol EO is a fatty acid ester formed by the condensation of oleic acid and ethanol, usually used as a solvent for pharmaceutical drug preparations.


IUPAC names
9-Octadecenoic acid (9Z)-, ethyl ester
ethyl (9Z)-octadec-9-enoate
ethyl (Z)-octadec-9-enoate
ethyl octadec-9-enoate
ethyl oleate

SYNONYMS:
(9Z)-9-Octadécénoate d'éthyle [French] [ACD/IUPAC Name]
(Z)-9-Octadecenoic Acid Ethyl Ester
111-62-6 [RN]
203-889-5 [EINECS]
2450
9-Octadecenoic acid, ethyl ester, (9Z)- [ACD/Index Name]
9Z-octadecenoic acid, ethyl ester
Ethyl (9Z)-9-octadecenoate [ACD/IUPAC Name]
Ethyl (9Z)-octadec-9-enoate
Ethyl cis-9-octadecenoate
Ethyl oleate
Ethyl-(9Z)-9-octadecenoat [German] [ACD/IUPAC Name]
Ethylis oleas
MFCD00009579 [MDL number]
Oleic Acid ethyl ester
Oleic acid, ethyl ester
RG3715000
(9Z)-9-Octadecenoic acid ethyl ester
(Z)-octadec-9-enoic acid ethyl ester
[111-62-6]
85049-36-1 [RN]
9-Octadecenoic acid (Z)-, ethyl ester
CIS-9-OCTADECENYL ACETATE
D04090
Elhyl oleate
ethyl (9Z)octadec-9-enoate
ethyl (9Z)-octadecenoate
ethyl (Z)-octadec-9-enoate
ethyl octadec-9-enoate
ethyl oleate 95%
Ethyl oleate (NF)
ethyl oleate food grade


 

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