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CYCLOHEXASILOXANE

Cyclohexasiloxane is mainly single component of cyclomethicone hexamer. 
Cyclohexasiloxane’s colorless and transparent liquid, without odor and irritation. 
Cyclohexasiloxane’s easy to use and spread, imparting soft and lubricious feel to skin and hair. 

CAS Number : 540-97-6
EC  Number : 208-762-8
Molecular Formula :     C12H36O6Si6
Molecular Weight  :     444.92
 
Cyclohexasiloxane is highly compatible with many cosmetic ingredients, without residues after evaporation. 
Cyclohexasiloxane can reduce surface tension, help to disperse pigments, widely used in personal care products such as make-up, skin care, hair care, sunscreen, antiperspirant, deodorant products.

Properties of Cyclohexasiloxane

-No oily feel
-With moderate volatility, can stay on skin or hair surface for some time.
-Compatible with many personal care ingredients.
-Stable.
-Make skin and hair lubricious, clear.
-Reduce surface tension, help to disperse pigments.
-Excellent spreadabiltiy.

Application of Cyclohexasiloxane

-Skin care, sunscreen products
-Make-up
-Hair care products
-Antiperspirants, deodorants

Cyclohexasiloxane is one of several forms of synthetic, cyclic (meaning the molecule is circular rather than straight or crosslinked) silicone used in cosmetic formulas to improve texture and enhance skin’s hydration. 
Cyclohexasiloxane helps give skin care products a silky-smooth, spreadable consistency, so key ingredients can be delivered evenly to skin.
Cyclohexasiloxane is also known to promote aesthetically pleasing finishes that don’t feel sticky, tacky or greasy after application. 
In hair care, Cyclohexasiloxane is used to add shine and reduce frizz.
As a raw material, cyclohexasiloxane is a colourless liquid. 
Cyclohexasiloxane is described as a lightweight carrier ingredient since it evaporates from skin, leaving behind the formula’s key ingredients to work effectively.

Cyclohexasiloxane is a common ingredient in skincare and body care products, used to improve the texture of formulations. 
While the texture is usually a sensory aspect of the product, in the case of cyclohexasiloxane, it helps the product to be evenly distributed so the key ingredients can improve the skin. 
Cyclohexasiloxane also has the added benefit of acting as a protective barrier to the skin, protecting the skin from moisture loss, allergens, and bacteria. 
Cyclohexasiloxane is a type of silicone. 
Silicones are synthetic polymers with a backbone composed of repeating units of siloxane, which is why silicones may also be referred to as polysiloxanes. 

Siloxane is made up of elemental silicon and oxygen. 
Often, the terms “silicone” and “silicon” are mistakenly used interchangeably, when they are quite different. 
Silicon is the 14th element on the periodic table and the second most abundant element in the earth’s crust after oxygen. 
In contrast, silicones are always synthetically produced.

Cyclohexasiloxane is part of a family of small silicones called cyclomethicones. 
Cyclohexasiloxane are clear, odorless liquids utilized in skincare products to give your skincare a smooth texture that allows the product’s key ingredients to be delivered evenly to the skin. 
Cyclohexasiloxane are part of the silicone family and are used in a similar way to dimethicone, which you may be familiar with. 
Cyclohexasiloxane help smooth the texture of products, improve the appearance of scarring, increase the water-resistance abilities of formulations, and emulsify the product. 
Cyclohexasiloxane are also better at delivering active ingredients to the skin as they are more volatile than larger silicones and slowly evaporate from the skin. 
When Cyclohexasiloxane disappear, they leave behind the formulation’s key ingredients.  

Cyclohexasiloxane are also known as cyclosiloxanes, different names for the same class of molecules. 
The two most commonly used cyclomethicones are cyclohexasiloxane and cyclohexasiloxane; you may have seen these ingredients somewhere near the bottom of your product’s ingredients list. 
Cyclohexasiloxane’s structure forms a ring which makes it more volatile or less stable. 
This instability allows cyclohexasiloxane to evaporate when applied to your skin readily. 
This characteristic makes cyclohexasiloxane a great ingredient for improving the spreadability of products and ensuring they don’t remain sticky after application. 
Cyclohexasiloxane gradually evaporates from the skin, leaving behind the other key components in the product to improve the appearance of the skin. 
This action of evaporation makes it an excellent carrier ingredient.  

Cyclohexasiloxane is one of several forms of synthetic, cyclic (meaning the molecule is circular rather than straight or crosslinked) silicone used in cosmetic formulas to improve texture and enhance skin’s hydration. 
Cyclohexasiloxane helps give skin care products a silky-smooth, spreadable consistency, so key ingredients can be delivered evenly to skin.
Cyclohexasiloxane is also known to promote aesthetically pleasing finishes that don’t feel sticky, tacky or greasy after application. 

In hair care, Cyclohexasiloxane is used to add shine and reduce frizz.
As a raw material, cyclohexasiloxane is a colorless liquid. 
Cyclohexasiloxane is described as a lightweight carrier ingredient since it evaporates from skin, leaving behind the formula’s key ingredients to work effectively.
Cyclohexasiloxane is an organosilicon compound.

Use and Manufacturing of Cyclohexasiloxane
The most important use, worldwide and in Canada, of Cyclohexasiloxane is as an ingredient in the formulation of personal care products and as an intermediate in the production of polydimethylsiloxanes (PDMS) silicone polymers ... Cyclohexasiloxane is also a constituent of cyclomethicone in the cosmetics industry ... In Canada, the most important uses of the mixtures of low molecular weight volatile cyclic siloxanes, which may contain a certain percentage of Cyclohexasiloxane, are in the preparation of personal care products including hair and skin care products, and antiperspirants ... Cyclohexasiloxane was reported for use as a defoamer ... Defoamers are employed often at parts per million levels in a range of processing industries including pulp and paper, food, petrochemical, petroleum, and chemical manufacture as well as water treatment. Silicones are also used as defoamers in household products such as cleaners and detergents.

Industry Uses of Cyclohexasiloxane
-Adhesives and sealant chemicals
-Anti-adhesive agents
-Diluent
-Dispersing agent
-Intermediate
-Intermediates
-Lubricants and lubricant additives
-Other (specify)
-Solvent
-Solvents (which become part of product formulation or mixture)
-Surfactant (surface active agent)
-Viscosity modifiers

Consumer Uses of Cyclohexasiloxane
-Adhesives and sealant chemicals
-Diluent
-Dispersing agent
-Intermediates
-Lubricants and lubricant additives
-Other (specify)
-Solvents (which become part of product formulation or mixture)
-Surfactant (surface active agent)

General Manufacturing Information    
Industry Processing Sectors
-All Other Basic Inorganic Chemical Manufacturing
-All Other Chemical Product and Preparation Manufacturing
-Asphalt Paving, Roofing, and Coating Materials Manufacturing
-Computer and Electronic Product Manufacturing
-Cyclic Crude and Intermediate Manufacturing
-Other (requires additional information)
-Rubber Product Manufacturing
-Synthetic Rubber Manufacturing
-Textiles, apparel, and leather manufacturing
-Wood Product Manufacturing

Cyclohexasiloxane is a clear fluid of low viscosity and high volatility and is one of the most common cost-effective ingredients used in personal care products today.
Cyclohexasiloxane is a volatile polydimethylcyclosiloxane composed mainly of cyclohexasiloxane. 
Cyclohexasiloxane is a base fluid in a number of personal care products, with excellent spreading and lubrication properties and unique volatility characteristics. 
Cyclohexasiloxane can be used in antiperspirants, skin creams, lotions and stick products, bath oils, makeup, suntan and shaving products.

Features & Benefits of Cyclohexasiloxane
-Volatile carrier
-Compatible with a wide range of cosmetic ingredients
-Low surface tension
-Imparts silky feel to the skin
-Excellent spreading
-Leaves no oily residue or build up
-Detackification
-Non-greasy

Applications of Cyclohexasiloxane
-A base fluid in a number of personal care products, with excellent spreading and lubrication properties and unique volatility characteristics.
-Can be used in antiperspirants, skin creams, lotions and stick products, bath oils, suntan and shaving products, make-up.
-In cleansing products XIAMETER™ PMX-0246 Cyclohexasiloxane lifts and removes dirt without a stinging sensation

Cyclohexasiloxane may be used alone or blended with other cosmetic fluids to provide a fluid base for a variety of cosmetic ingredients.
Cyclohexasiloxane features good solubility in most anhydrous alcohols and in many cosmetic solvents.
Cyclohexasiloxane is a volatile fluid with appreciable vapor pressure at ambient temperature.
Note that the pentamer component (D5) evaporates at a faster rate than the hexamer Cyclohexasiloxane.
By using blends of Cyclohexasiloxane this difference in volatility can be used to vary the residence time of the silicone on the skin.
Unlike other volatile carriers used in the personal care industry, volatile silicone fluids do not cool the skin when they evaporate. 
This is a consequence of their unusually low heat of vaporization.

FUNCTION of Cyclohexasiloxane
Used for excellent spreading, fast evaporation leaving no residue or build-up, leaves a unique soft feel and lubricity; non-greasy feel, non-occlusive and non-irritating. 
Used in conditioners, hair sprays, face wash, body wash, make-up, sun care, antiperspirants, and deodorants.

Cyclohexasiloxane can be frustrating to decipher the long chemical names on the label of your favorite cosmetic products. 
Simple ingredients like water and alcohol are easy to recognize. 
But lengthy chemical names can leave even the most conscious consumers scratching their heads.

Cyclohexasiloxane is a silicone regularly used in cosmetic products. 
Cyclohexasiloxane’s commonly found in medical implants, sealants, lubricants, and windshield coatings.
Cyclohexasiloxane is colorless, odorless, non-greasy, and water-thin. 
Cyclohexasiloxane doesn’t get absorbed into the skin. 
Rather, Cyclohexasiloxane evaporates quickly away from it. 
This property makes it a useful ingredient in cosmetic products that need to dry quickly, like antiperspirants and hair sprays.
D5 is known for being able to evaporate and dry quickly. Silicones are also known to repel water and glide easily. This is why they are commonly used as ingredients in lubricants and sealants.

They are also known to form a protective barrier on the skin and hair. 
This can help you detangle your hair, prevent breakage, and reduce frizz.

Cyclohexasiloxane can be found in a wide range of personal care products. Examples include:

-hair spray
-sunscreen
-antiperspirant
-deodorant
-hair conditioner
-shampoo
-hair detangling products
-waterproof mascara
-foundation
-eyeliner
-concealer
-moisturizer with SPF
-eye shadow
-hairstyling gel and lotion
-lipstick

Cyclohexasiloxanes belong to the group of siloxanes and are organic silicon compounds.
Cyclohexasiloxane are ring-shaped compounds in which silicon and oxygen are bonded alternately and two methyl groups are additionally attached to the silicon.
Cyclohexasiloxane consists of a ring with 6 silicon and 6 oxygen atoms, the "sister compounds", cyclohexasiloxane  consists of a ring with 5 silicon and 5 oxygen atoms and cyclotetrasiloxane (D4) consists of a ring with 4 silicon and 4 4 oxygen atoms.

Mixtures of Cyclohexasiloxane and D6 are also available on the market and are also often used in cosmetics. 
The term silicone is often used in public, but this general placeholder does not do justice to the many other types of silicone. 
The raw materials should be named here with the exact designation, because the dimethicones, silicone elastomers, dimethiconols, silicone gums and silicone emulsifiers have a different structure and sometimes have completely different properties.
All silicone compounds have a very low water solubility in common and cyclohexasiloxane in particular is also often used in body products, sun protection products and ColorCare because of its low density and stickiness.


FIRST AID MEASURES of Cyclohexasiloxane

Skin Contact:
Wash off immediately with soap and plenty of water removing all contaminated clothing and shoes. 
Get medical attention. 
If skin irritation persists, call a physician. 

Eye Contact: 
Flush eyes with water for 15 minutes. 
Get medical attention.

Inhalation: 
Move to fresh air. 
If not breathing, give artificial respiration. 
If breathing is difficult, give oxygen. 
Get medical attention.

Ingestion: 
Do not induce vomiting without medical advice. 
Never give anything by mouth to an unconscious person. 
Consult a physician if necessary.

Substance identity

EC / List no.: 208-762-8
CAS no.: 540-97-6
Mol. formula: C12H36O6Si6

Hazard classification & labelling of Cyclohexasiloxane
According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified.

About Cyclohexasiloxane
Cyclohexasiloxane is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Cyclohexasiloxane is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses of Cyclohexasiloxane
Cyclohexasiloxane is used in the following products: washing & cleaning products, polishes and waxes and cosmetics and personal care products.
Other release to the environment of Cyclohexasiloxane is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

Article service life of Cyclohexasiloxane
ECHA has no public registered data on the routes by which Cyclohexasiloxane is most likely to be released to the environment. 
ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

Widespread uses by professional workers of Cyclohexasiloxane
Cyclohexasiloxane is used in the following products: cosmetics and personal care products, polishes and waxes, washing & cleaning products and semiconductors.
Cyclohexasiloxane is used in the following areas: health services and formulation of mixtures and/or re-packaging.
Other release to the environment of Cyclohexasiloxane is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

Formulation or re-packing of Cyclohexasiloxane
Cyclohexasiloxane is used in the following products: polishes and waxes, washing & cleaning products, cosmetics and personal care products and pharmaceuticals.
Release to the environment of Cyclohexasiloxane can occur from industrial use: formulation of mixtures and formulation in materials.

Uses at industrial sites of Cyclohexasiloxane
Cyclohexasiloxane is used in the following products: polymers, washing & cleaning products, laboratory chemicals and polishes and waxes.
Cyclohexasiloxane has an industrial use resulting in manufacture of another substance (use of intermediates).
Cyclohexasiloxane is used in the following areas: scientific research and development.
Cyclohexasiloxane is used for the manufacture of: chemicals.
Release to the environment of Cyclohexasiloxane can occur from industrial use: for thermoplastic manufacture, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.

Manufacture of Cyclohexasiloxane
Release to the environment of Cyclohexasiloxane can occur from industrial use: manufacturing of the substance.

Synonyms:
Dodecamethylcyclohexasiloxane
dodecamethylcyclohexasiloxane
Dodecamethylcyclohexasiloxane
D6
Dodecamethylcyclohexasiloxane; D6
Cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-
2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
D6
Dodecamethyl cyclohexasiloxane
DODECAMETHYLCYCLOHEXASILOXANE
Dodecamethylcyclohexasiloxane
dodecamethylcyclohexasiloxane
Dodecamethylcyclohexasiloxane
dodecamethylcyclohexasiloxane, D6
Baysilone SF 1217
Dodecamethylcyclohexasiloxane
DOW CORNING(R) 246 FLUID
Silsoft 1217
540-97-6
DODECAMETHYLCYCLOHEXASILOXANE
540-97-6
Cyclohexasiloxane, dodecamethyl-
Cyclomethicone 6
2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
Cyclohexasiloxane
XHK3U310BA
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane
EINECS 208-762-8
UNII-XHK3U310BA
HSDB 7723
EC 208-762-8
dodecamethyl cyclohexasiloxane
SCHEMBL93785
XIAMETER PMX-0246
CYCLOHEXASILOXANE [INCI]
DTXSID6027183
IUMSDRXLFWAGNT-UHFFFAOYSA-
CHEBI:191103
CYCLOMETHICONE 6 [USP-RS]
MFCD00144215
AKOS015839990
ZINC169794506
FS-5671
DODECAMETHYLCYCLOHEXASILOXANE [MI]
DODECAMETHYLCYCLOHEXASILOXANE [HSDB]
DB-008587
D2040
DODECAMETHYLCYCLOHEXASILOXANE [WHO-DD]
FT-0625566
S08515
T71035
Dodecamethylcyclohexasiloxane, analytical standard
A914553
Q27293843
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane #
Cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane 95%
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane, 95%
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane, AldrichCPR
Cyclomethicone 6, United States Pharmacopeia (USP) Reference Standard
2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexa
D-6
2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane
208-762-8 [EINECS]
540-97-6 [RN]
Cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl- [ACD/Index Name]
CYCLOMETHICONE 6
Dodecamethylcyclohexasiloxan [German] [ACD/IUPAC Name]
Dodecamethylcyclohexasiloxane [ACD/IUPAC Name]
Dodécaméthylcyclohexasiloxane [French] [ACD/IUPAC Name]
MFCD00144215
CYCLOHEXASILOXANE, DODECAMETHYL-
DC 246 fluid
dodecamethyl cyclohexasiloxane
dodecamethyl-cyclohexasiloxane
Dodecamethylcyclohexasiloxane|DC 246 fluid
EINECS 208-762-8
XHK3U310BA [DBID]
UNII:XHK3U310BA [DBID]
UNII-XHK3U310BA [DBID]

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