CYCLOHEXYLAMINE

CAS Number 108-91-8

Synonyms:
sikloheksilamin; sikloheksilamine; CYCLOHEXYLAMİNE; Cyclohexylamine; siklo heksilamin; siklo heksilamine; CYCLO HEXYLAMINE; Cyclo hexylamine; CYCLOHEXYLAMİNE; Cyclohexanamine; 108-91-8;Aminocyclohexane;Hexahydroaniline;Hexahydrobenzenamine;Aminohexahydrobenzene;1-Cyclohexylamine;1-Aminocyclohexane;Cyclohexyl amine;Aniline, hexahydro-;Benzenamine, hexahydro-;Cyclohexylamines;Aminocylcohexane;cyclohexyl-amine;UNII-I6GH4W7AEG;CCRIS 3645;HSDB 918;EINECS 203-629-0;UN2357;1-AMINO-CYCLOHEXANE;BRN 0471175;Cyclohexylamin;AI3-15323;CHEBI:15773;PAFZNILMFXTMIY-UHFFFAOYSA-N;SBB040492;Cyclohexylamine [UN2357][Corrosive]; DSSTox_CID_3996; DSSTox_RID_77250; DSSTox_GSID_23996; CAS-108-91-8; cyclohexaneamine; cyclohexylarnine ;cyclo-hexylamine; Cyclohex-ylamine; cyclohexane-amine;cyclohexanyl amine;monocyclohexylamine;4-Cyclohexylamine;ACMC-1BUGG;AC1L1PYL;HAI;Cyclohexylamine, 99.5%;I6GH4W7AEG;bmse000451;AC1Q53FD;AC1Q53FE;4-12-00-00008 (Beilstein Handbook Reference);BIDD:ER0290;GTPL5507;CHEMBL1794762;Cyclohexylamine, 98% 100ml;DTXSID1023996;BDBM81970;CTK0H8608;MolPort-000-871-531;Tox21_202380;Tox21_300038;ANW-15993;BBL002476;LS-473;MFCD00001486;STK387114;ZINC12358775;AKOS000119083;Cyclohexylamine, ReagentPlus(R), 99%;MCULE-7654331405;RP18677;TRA0041577;TRA0099304;UN 2357;Cyclohexylamine [UN2357] [Corrosive];NCGC00247889-01;NCGC00247889-02;NCGC00253922-01;NCGC00259929-01;AJ-61330;AM802905;AN-42915;BC206665;BP-21278;CAS_108-91-8;KB-49244;NCI60_004907;OR034048;OR226448;SC-47180;TC-104738;TR-002007;Cyclohexylamine, ReagentPlus(R), >=99.9%;FT-0624217;ST45255365;T7305;X6008;C00571;46880-EP2272837A1;46880-EP2277848A1;46880-EP2277862A2;46880-EP2281563A1;46880-EP2284159A1;46880-EP2284174A1;46880-EP2287141A1;46880-EP2292228A1;46880-EP2292621A1;46880-EP2295406A1;46880-EP2295418A1;46880-EP2298731A1;46880-EP2298746A1;46880-EP2298778A1;46880-EP2305219A1;46880-EP2305651A1;46880-EP2308812A2;46880-EP2308833A2;46880-EP2308854A1;46880-EP2311804A2;46880-EP2311810A1;46880-EP2380874A2;56751-EP2284166A1;56751-EP2298769A1;56751-EP2308878A2;I05-0465;J-002206;J-520164;I14-21057;F2190-0381;InChI=1/C6H13N/c7-6-4-2-1-3-5-6/h6H,1-5,7H;143247-75-0;157973-60-9;Cyclohexylamine;Cyclohexylamines;108-91-8 [RN];1-Aminocyclohexane;1-AMINO-CYCLOHEXANE;1-Cyclohexylamine;Aminocyclohexane;aminohexahydrobenzene;Aniline, hexahydro-;Benzenamine, hexahydro-;Cyclohexanamin [German] [ACD/IUPAC Name];Cyclohexanamine [ACD/Index Name] [ACD/IUPAC Name];Cyclohexanamine [French] [ACD/Index Name] [ACD/IUPAC Name];cyclohexyl amine;Cyclohexylamine [Wiki];Hexahydroaniline;N-Cyclohexylamine;[108-91-8];143247-75-0 [RN];157973-60-9 [RN];203-629-0 [EINECS];26227-54-3 [RN];4-12-00-00008 (Beilstein Handbook Reference) [Beilstein];6850-39-1[RN];Aminocylcohexane; ANL; CHA; ciclo-hexilamina [Portuguese];Cyclohexanamine, 9CI;Cyclohexylamine [UN2357] [Corrosive];Cyclohexylamine [UN2357] [Corrosive];Cyclohexylamine Solution, 1,000 mg/L, 1 ml (RM, ISO GUIDE 34);CYCLOHEXYLAMINE, 99%;cyclohexylammonium;EINECS 203-629-0;HAI;Hexahydro-Aniline;Hexahydro-Benzenamine;HEXAHYDROBENZENAMINE;InChI=1/C6H13N/c7-6-4-2-1-3-5-6/h6H,1-5,7H;ST5213819;trans-2-aminocyclohexane;UN 2357;UNII:I6GH4W7AEG ;UNII I6GH4W7AEG; AMINOCYCLOHEXANE; 1-AMINOCYCLOHEXANE; AMINOHEXAHYDROBENZENE; BENZENAMINE, HEXAHYDRO-;CHA;CYCLOHEXANAMINE;CYCLOHEXYLAMINE;1-CYCLOHEXYLAMINE; HEXAHYDROANILINE; HEXAHYDROBENZENAMINE; MONOCYCLOHEXYLAMINE; Aminocyclohexane, Cyclohexanamine;1-Aminocyclohexane;1-Cyclohexylamine;aminocyclohexa[qr]; Aminohexahydrobenzene; aminohexahydrobenzene[qr]; Aniline, hexahydro-;Benzenamine, hexahydro-;benzenamine,hexahydro-[qr];Cyclohexane Aniline; (cyclohexylamine)trifluoroboron O,O-diisopropyl hydrogen dithiophosphate, compound with cyclohexylamine (1:1) N-[[5-(dimethylamino)-1-naphthyl]sulphonyl]-L-methionine, compound with cyclohexylamine (1:1) 1,8-DIAMINO-P-MENTHANE 1,2-Diaminocyclohexane N-Cyclohexyl-2-pyrrolidone TRANS-2-AMINOCYCLOHEXANOL HYDROCHLORIDE N-Cyclohexyltaurine N-CYCLOHEXYLFORMAMIDE 1-Amino-1-cyclohexanecarboxylic acid 2-NITROCYCLOHEXANONE Sodium N-cyclohexylsulfamate N,N'-DICYCLOHEXYLDITHIOOXAMIDE N,N'-DICYCLOHEXYLUREA Cyclohexylamine Methylcyclohexane;Aminocyclohexane; Aminohexahydrobenzene; Aniline Hexahydro; CHA; Hexahydrobenzenamine;Cyclohexanamine; Aminocyclohexane; Aminohexahydrobenzene; Benzenamine, hexahydro-; Hexahydroaniline; Hexahydrobenzenamine; Aniline, hexahydro-; CHA; UN 2357; 1-Aminocyclohexane; 1-Cyclohexylamine;Hexahydroaniline, Cyclohexaneamine;Cyclohexanamine; Aminocyclohexane; CHA; Cyclohexylamine;;Hexahydrobenzenamine; Aminohexahydrobenzene; Hexahydroaniline; 1-Aminocyclohexane; 1-Cyclohexylamine;;Cyclohexanamine (IUPAC Name); 1-Aminocyclohexane; 1-Amino-cyclohexane; 1-Cyclohexylamine; Aminocyclohexane; aminohexahydrobenzene; Hexahydro-aniline; Hexahydro-benzenamine; cyclohexyl amine; Hexahydroaniline; N-Cyclohexylamine; Aminocyclohexane;Aminocyclohexane; Aminohexahydrobenzene; Cyclohexanamine; Hexahydroaniline; Hexahydrobenzenamine; Aminocyclohexane; aminocyclohexane; hexahydroaniline;cyclohexanamine; aminocyclohexane;hexahydroaniline; hexahydrobenzenamine;hexahydroaniline, aminocyclohexane,cyclohexanamine, aminohexahydrobenzene,Cyclohexyl amine; Cyclohexanamine; Benzenamine, hexahydro-; ANL; CHA; Hexahydrobenzenamine; aminohexahydrobenzene; cyclohexanamine; Aminohexahydrobenzene; Cyclohexylamine [UN2357] [Corrosive]; 1-AMINO-CYCLOHEXANE;Cyclohexanamine, Aminocyclohexane, Aminohexahydrobenzene, Hexahydroaniline, Hexahydrobenzenamine; Aminocyclohexane ;CHA;Cyclohexaneamine; Cyclohexylamine; Hexahydroaniline; carboxy-isophosphamide cyclohexylamine; Cyclohexylamine, Cyclohexylamine Benzoate, Cyclohexylamine Carbonate, Trans-4-MethylCyclohexylamine Hydrochloride; Aminocyclohexane, Aminohexahydrobenzene, Hexahydroaniline; cyclohexanamine; Cyclohexylamine; siklohekzilamin; sikloheksilamin; siklohegzilamin; siklohegsilamin; siklo hekzilamin; siklohekzil amin; siklo hekzil amin; siklo hegzilamin; siklohegzil amin; siklo hegzil amin; Cyclohexylamines; CYCLOHEXYLAMINE; Cyclohexanamine; Aminocyclohexane; 108-91-8; Hexahydroaniline; Hexahydrobenzenamine; Aminohexahydrobenzene; 1-Cyclohexylamine; 1-Aminocyclohexane; Cyclohexyl amine; Aniline, hexahydro-; Aminocylcohexane; Cyclohexylamines; Benzenamine, hexahydro-; cyclohexyl-amine; 1-AMINO-CYCLOHEXANE; Cyclohexylamine.HCl; Cyclohexylamin; cyclohexaneamine; cyclohexylarnine; cyclo-hexylamine; Cyclohex-ylamine; cyclohexane-amine; cyclohexanyl amine; Hexahydro-Aniline monocyclohexylamine; 4-Cyclohexylamine; Hexahydro-Benzenamine; Cyclohexanamine, 9CI; CYCLOHEXYLAMINE; Cyclohexanamine; 108-91-8; Aminocyclohexane; Hexahydroaniline; Hexahydrobenzenamine; Aminohexahydrobenzene; 1-Cyclohexylamine; 1-Aminocyclohexane; Aniline, hexahydro-; Cyclohexyl amine; Benzenamine, hexahydro-; Cyclohexylamines; Aminocylcohexane; cyclohexyl-amine; UNII-I6GH4W7AEG; CCRIS 3645; HSDB 918; EINECS 203-629-0, UN2357; 1-AMINO-CYCLOHEXANE; BRN 0471175; Cyclohexylamin; AI3-15323; Cyclohexylamine [UN2357] [Corrosive]; cyclohexaneamine; cyclohexylarnine; cyclo-hexylamine; Cyclohex-ylamine; cyclohexane-amine; cyclohexanyl amine monocyclohexylamine; 4-Cyclohexylamine; Cyclohexylamine, 99.5%; 1-Aminocyclohexane;1-Cyclohexylamine;aminocyclohexan [qr]; Aminohexahydrobenzene;aminohexahydrobenzene[qr]; Aniline, hexahydro-;Benzenamine,hexahydro-; benzenamine, hexahydro-[qr]; SIKLO HEKSILAMIN; SIKLOHEKSILAMIN ;SİKLO HEKSİLAMİN; SİKLOHEKSİLAMİN; cyclohexyl amine;CYCLOHEXYL AMINE; CYCLOHEXYLAMINE; cyclohexylamine; siklo heksilamin; sikloheksilamin; sıklo heksılamın; sıkloheksılamın; siklo helsilamin; SIKLO HEKSILAMIN; sıkloheksıamın
 

Cyclohexylamine

Cyclohexylamine[1]
Cyclohexylamine-2D-skeletal.png
Cyclohexylamine-3D-balls.png
Names
IUPAC name
Cyclohexanamine
Other names
Aminocyclohexane
Aminohexahydrobenzene
Hexahydroaniline
Hexahydrobenzenamine
Identifiers
CAS Number    
108-91-8 ☑
3D model (JSmol)    
Interactive image
3DMet    
B00135
ChEBI    
CHEBI:15773 ☑
ChEMBL    
ChEMBL1794762
ChemSpider    
7677 ☑
ECHA InfoCard    100.003.300 Edit this at Wikidata
EC Number    
203-629-0
IUPHAR/BPS    
5507
KEGG    
C00571 ☑
PubChem CID    
7965
RTECS number    
GX0700000
UNII    
I6GH4W7AEG ☑
CompTox Dashboard (EPA)    
DTXSID1023996 Edit this at Wikidata
InChI[show]
SMILES[show]
Properties
Chemical formula    C6H13N
Molar mass    99.17
Appearance    clear to yellowish liquid
Odor    strong, fishy, amine odor
Density    0.8647 g/cm3
Melting point    −17.7 °C (0.1 °F; 255.5 K)
Boiling point    134.5 °C (274.1 °F; 407.6 K)
Solubility in water    Miscible
Solubility    very soluble in ethanol, oil
miscible in ethers, acetone, esters, alcohol, ketones
Vapor pressure    11 mmHg (20° C)[2]
Acidity (pKa)    10.64[3]
Refractive index (nD)    1.4565
Hazards
GHS pictograms    GHS02: FlammableGHS05: CorrosiveGHS07: HarmfulGHS08: Health hazard
GHS Signal word    Danger
GHS hazard statements    H226, H302, H312, H314, H361
GHS precautionary statements    P201, P202, P210, P233, P240, P241, P242, P243, P260, P264, P270, P280, P281, P301+312, P301+330+331, P302+352, P303+361+353, P304+340, P305+351+338, P308+313, P310, P312, P321, P322, P330
NFPA 704 (fire diamond)    
NFPA 704 four-colored diamond
330
Flash point    28.6 °C (83.5 °F; 301.8 K)
Autoignition
temperature    293 °C (559 °F; 566 K)
Explosive limits    1.5–9.4%[2]
Lethal dose or concentration (LD, LC):
LD50 (median dose)    156 mg/kg (rat, oral)
NIOSH (US health exposure limits):
PEL (Permissible)    none[2]
REL (Recommended)    TWA 10 ppm (40 mg/m3)[2]
IDLH (Immediate danger)    N.D.[2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Cyclohexylamine is an organic compound, belonging to the aliphatic amine class. It is a colorless liquid, although, like many amines, samples are often colored due to contaminants. It has a fishy odor and is miscible with water. Like other amines, it is a weak base, compared to strong bases such as NaOH, but it is a stronger base than its aromatic analog, aniline.

It is a useful intermediate in the production of many other organic compounds (e.g cyclamate)

Contents
1    Preparation
2    Applications
3    Toxicity
4    References
Preparation
Cyclohexylamine is produced by two routes, the main one being the complete hydrogenation of aniline using some cobalt- or nickel-based catalysts:[4]

C6H5NH2 + 3 H2 → C6H11NH2
It is also prepared by alkylation of ammonia using cyclohexanol.

Applications
Cyclohexylamine is used as an intermediate in synthesis of other organic compounds. It is the precursor to sulfenamide-based reagents used as accelerators for vulcanization. It is a building block for pharmaceuticals (e.g., mucolytics, analgesics, and bronchodilators). The amine itself is an effective corrosion inhibitor. Some sweeteners are derived from this amine, notably cyclamate. The herbicide hexazinone and the anesthetic hexylcaine are derived from cyclohexylamine.[4]

Toxicity
LD50 (rat; p.o.) = 0.71 ml/kg[5]

It is corrosive. Cyclohexylamine is listed as an extremely hazardous substance as defined by Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act. It has been used as a flushing aid in the printing ink industry.[6]

The National Institute for Occupational Safety and Health has suggested workers not be exposed to a recommended exposure limit of over 10 ppm (40 mg/m3) over an eight-hour workshift
Cyclohexylamine appears as a clear colorless to yellow liquid with an odor of ammonia. Flash point 90°F. Irritates the eyes and respiratory system. Skin contact may cause burns. Less dense than water. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion.

CAMEO Chemicals
Cyclohexylamine is a primary aliphatic amine consisting of cyclohexane carrying an amino substituent. It has a role as a human xenobiotic metabolite and a mouse metabolite. It is a conjugate base of a cyclohexylammonium.

Molecular Weight of Cyclohexylamine:    99.17 g/mol    Computed by PubChem 2.1 (PubChem release 2019.06.18)
XLogP3    1.5    Computed by XLogP3 3.0 (PubChem release 2019.06.18)
Hydrogen Bond Donor Count of Cyclohexylamine:    1    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Hydrogen Bond Acceptor Count of Cyclohexylamine:    1    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Rotatable Bond Count of Cyclohexylamine:    0    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Exact Mass     of Cyclohexylamine:99.104799 g/mol    Computed by PubChem 2.1 (PubChem release 2019.06.18)
Monoisotopic Mass of Cyclohexylamine:    99.104799 g/mol    Computed by PubChem 2.1 (PubChem release 2019.06.18)
Topological Polar Surface Area of Cyclohexylamine:    26 Ų    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Heavy Atom Count of Cyclohexylamine:7    Computed by PubChem
Formal Charge of Cyclohexylamine:    0    Computed by PubChem
Complexity of Cyclohexylamine:    46.1    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Isotope Atom Count of Cyclohexylamine:    0    Computed by PubChem
Defined Atom Stereocenter Count of Cyclohexylamine:0    Computed by PubChem
Undefined Atom Stereocenter Count of Cyclohexylamine:    0    Computed by PubChem
Defined Bond Stereocenter Count     of Cyclohexylamine:0    Computed by PubChem
Undefined Bond Stereocenter Count of Cyclohexylamine:    0    Computed by PubChem
Covalently-Bonded Unit Count of Cyclohexylamine:    1    Computed by PubChem
Compound Is Canonicalized of Cyclohexylamine:    Yes

General description
A clear, colorless to yellow liquid with an ammonia odor. Flash point 90 ° F. Irritating to eyes and respiratory system. Contact with skin may cause burns. Less dense than water. Vapors heavier than air. Toxic nitrogen oxides produced on combustion.

The main purpose of cyclohexylamine can be used as a raw material of surfactants for the production of alkylbenzene sulfonate to be used as an emulsifier and foaming agent;
It can be used as a raw material for making perfume for the production of cyclohexyl allyl propionate;
It can be used as the raw material for dye production, such as for the production of Acid Blue 62, Fluorescent Yellow Dispersion, Fluorescent Yellow Dispersion H5GL, Weak Acid Blue BRN, Disperse Blue 6, and Dye Additives ;
It can be used as a raw material of food additive sweeteners; cyclohexylamine can also be used to produce salts of cyclohexylamine sulfonate and sodium cyclamate; the latter is a sweeter one which is 30 times sweeter than sucrose. The Chinese Ministry of Health has approved it for its application to pickles, sauces, wine preparation, cakes, cookies, bread, frozen drinks and beverages with a maximum allowable amount of 0.65 g / kg.
It can be used as a pesticide raw material such as insecticide "propargite" for the production of fruit trees, herbicides "WilBur" and bactericidal agent;
It can be used in the preparation of additives used in petroleum products, boiler feed water treatment agent and corrosion remover;
It can be used as a raw material for the production of CZ rubber thiazole vulcanization accelerator; this type of vulcanization accelerator has excellent efficiency which is particularly suitable for SBR and FDA rubbers.
It can be used as a rust inhibitor for the production of anti-rust paper;
It can be used as a tank cleaning agent;
It can be used as an antifreeze agent;
It can be used as antistatic agents (textile auxiliaries), latex agglutinating agents and additives for petroleum products;
Due to the alkalinity of the aqueous cyclohexylamine solution, it can be used as an absorber to remove carbon dioxide and sulfur dioxide.

Applications
Intermediate used in the production of:
• Corrosion inhibitors
• Pharmaceutical products
• Rubber chemicals

GENERAL DESCRIPTION AND EXTERNAL LINKS

Cyclohexane is the six-membered alicyclic hydrocarbon made up of six carbon atoms bonded to each other to form a ring, with each carbon atom carrying two hydrogen atoms, C6H12. A cyclic compound is an organic compound that contains one or more closed rings of carbon atoms. The term alicyclic refers to a cyclic compound that chemically behaves like aliphatic (open chain) compounds, meaning the exclusion of carbocyclic compounds from aromatic rings with an electron matrix ¥? Feature. Cyclohexane is a colorless, highly flammable, mobile liquid with a pungent odor. It is insoluble in water and soluble in alcohol, ether, and almost organic solvents. Cyclohexane is a non-corrosive, rapidly volatilizing liquid and sublimates between -5 and 5 C. Cyclohexane can exist in a number of interconvertible three-dimensional conformations, the two simplest being the chair and boat conformation and others include the half-chair and twist-chair conformation. Cyclohexane can cause eye and mucous membrane irritation in workers. Repeated and prolonged contact with the skin may cause dermatitis. The substance has not been shown to cause the haematological changes associated with exposure to benzene. Cyclohexane is found naturally in crude oils. Part of the cyclohexane is recovered from petroleum streams by fractionation. The voluminous commercial production of cyclohexane is based on the hydrogenation of benzene in a closed system. The consumption of cyclohexane is almost entirely related to the production of nylon. The nylon is then made into fibers for applications in carpets, automotive tire cords, clothing and other growing industrial fields. Cyclohexane is used as a solvent, oil extractor, paint and varnish remover, dry cleaning equipment and in solid fuels. It was used as an insecticide itself. Cyclohexane is used as a chemical intermediate to produce the target molecules.
The six-membered cyclohexane structure is one of nature's main backbones. Cyclohexane derivatives can be used for the synthesis of pharmaceuticals, dyes, herbicides, plant growth regulator, plasticizers, rubber chemicals, cycloamines and other organic compounds.

Cyclohexylamine is used as an intermediate for the synthesis of

Herbicides (for example, S-ethyl N-ethyl cyclohexyl thiocarbamate)
Antioxidants and vulcanization accelerator (eg N-cyclohexyl 2-benzothiazole sulfenamide)
Mucolytics
Broncodialators (eg, bromhexine HCl)
Analgesic agents
Additive for CO2 prevention
Corrosion inhibitor in steam pipes and boilers
Urethane chain stopper
Artificial sweetener such as cyclamates.

APPLICATION AREA
Cyclohexylamine is used in particular for the treatment of industrial water, for the production of hardening accelerator, for the manufacture of synthetic sweeteners and
in a rubber industry for the production of vulcanization accelerators.

Main features and benefits
Condensate line treatment
Prevent corrosion of carbon dioxide
Prevents formation of carbonic acid in the boiler steam system
Does not add boiler water to the TDS
Completely volatile

Cyclohexylamine is used as a corrosion inhibitor in boiler feed water and has important applications as a chemical intermediate in organic synthesis and in the
manufacture of insecticides, plasticizers, dry cleaning soaps, rubber chemicals, dyes and gas absorbers

Applications

Agriculture
Chemical industry
Chemical synthesis
Colorants, pigments and optical brighteners
Energy Food industry Hardener and crosslinkers for polymers
Lubricants and oils for industrial water
Manufacture of diabetics Manufacture of dyes
Manufacture of herbicides Manufacture of insecticides / acaricides
Manufacture of pharmaceutical agents
Pigment manufacturing
Manufacture of sweeteners
Manufacture of textile dyes
Manufacture of textile dyes
Pesticides
Petrochemicals
Oil
Pharmaceutical industry / Biotechnology Pigments Plastic polymers and rubbers Polymer auxiliaries
Polymerization initiator
Specialties
Stabilizers for explosives T
extile dyes
Textile industry
Water treatment

In organic synthesis, manufacture insecticides, plasticizers, emulsifiers, dry cleaning soaps, acid gas absorbents.

CYCLOHEXYLAMINE
Cyclohexylamine is an organic compound belonging to the class of aliphatic amines. It is a colorless liquid, although, like many amines, samples are often stained due to contaminants. It has a fishy odor and is miscible with water. Like other amines, it is a poor base, compared to strong bases such as NaOH, but it is a stronger base than its aromatic analogue, aniline.
It is a useful intermediate in the production of many other organic compounds. It is a metabolite of cyclamate.

Cyclohexylamine is used as an intermediate in the synthesis of other organic compounds. It is the precursor of sulfenamide-based reagents used as vulcanization accelerators. It is a building block in pharmaceuticals (eg, mucolytics, pain relievers, and bronchodilators). The amine itself is an effective corrosion inhibitor. Certain sweeteners are derived from this amine, in particular cyclamate. Hexazinone herbicide is derived from cyclohexylamine.