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Cyclopentasiloxane D5 is a silicone regularly used in cosmetic products.
Cyclopentasiloxane D5’s commonly found in medical implants, sealants, lubricants, and windshield coatings.
Cyclopentasiloxane D5 is colorless, odorless, non-greasy, and water-thin.
CAS Number: 541-02-6
Molecular Formula: C10H30O5Si5
Molecular Weight: 370.77
EINECS Number: 208-764-9
Synonyms: DECAMETHYLCyclopentasiloxane D5, 541-02-6, Cyclopentasiloxane D5, decamethyl-, Cyclomethicone 5, 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane, Cyclopentasiloxane D5, Dimethylsiloxane pentamer, Dekamethylcyklopentasiloxan, Dow corning 345, NUC silicone VS 7158, Silicon SF 1202, Ciclopentasiloxane, Cyclic dimethylsiloxane pentamer, Cyclomethicone D5, D5-sil, KF 995, CCRIS 1328, VS 7158, HSDB 5683, UNII-0THT5PCI0R, 0THT5PCI0R, EINECS 208-764-9, SF 1202, BRN 1800166, DTXSID1027184, JEESILC CPS-211, XIAMETER PMX-0245, DTXCID907184, Cyclopentasiloxane D5 (D5), D5, EC 208-764-9, 4-04-00-04128 (Beilstein Handbook Reference), KF-995, DOW CORNING ST CYCLOMETHICONE 5, OCTAMETHYLCYCLOTETRASILOXANE (D5), KP-545 COMPONENT CYCLOMETHICONE 5, 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane, Cyclopentasiloxane D5, 2,2,4,4,6,6,8,8,10,10-decamethyl-, CYCLOMETHICONE 5 (USP-RS), CYCLOMETHICONE 5 [USP-RS], MFCD00046966, Dekamethylcyklopentasiloxan [Czech], DdecamethylCyclopentasiloxane D5, decamethyl Cyclopentasiloxane D5, C10H30O5Si5, Lightening Serum, Cyclopentasiloxane D5, dimethylCyclopentasiloxane D5, Decamethylcylopentasiloxane, UNII: 0THT5PCI0R, SCHEMBL28497, N-Propylheptamethyltrisiloxane, CHEMBL1885178, Cyclopentasiloxane D5 [INCI], 3CE PINK IM GOOD MASCARA, CHEBI:191092, DecamethylCyclopentasiloxane D5, 97%, XMSXQFUHVRWGNA-UHFFFAOYSA-N, CYCLOMETHICONE 5 [WHO-DD], BCP15826, Tox21_303170, CD3770, Cyclopentasiloxane D5, DECAMETHYL, AKOS008901199, CS-W009767, DB11244, HY-W009051, DECAMETHYLCyclopentasiloxane D5 [MI], NCGC00163981-01, NCGC00257224-01, AS-59731, CAS-541-02-6, DECAMETHYLCyclopentasiloxane D5 [HSDB], D1890, D3770, DecamethylCyclopentasiloxane D5 (cyclic monomer), FT-0665531, NS00043162, D78203, S05475, DecamethylCyclopentasiloxane D5, analytical standard, Q414350, decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane, Cyclomethicone 5, United States Pharmacopeia (USP) Reference Standard, 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane.
Cyclopentasiloxane D5 doesn’t get absorbed into the skin.
Rather, Cyclopentasiloxane D5 evaporates quickly away from it.
This property makes Cyclopentasiloxane D5 a useful ingredient in cosmetic products that need to dry quickly, like antiperspirants and hair sprays.
Cyclopentasiloxane D5 also has lubricating properties.
This gives a slippery and silky feeling when applied to the skin and hair and allows Cyclopentasiloxane D5 to spread more easily.
As if the name "Cyclopentasiloxane D5" wasn't hard enough to say, we should point out that it's also known as decamethylCyclopentasiloxane D5.
This property contributes to a smooth and lightweight feel upon application.
Cyclopentasiloxane D5 enhances the spreadability of cosmetic products and provides a silky, non-greasy texture.
Cyclopentasiloxane D5 helps in the even distribution of other ingredients in formulations.
Cyclopentasiloxane D5 acts as an emollient, imparting a soft and smooth texture to the skin or hair.
Cyclopentasiloxane D5 can improve the appearance of cosmetic formulations, giving them a luxurious and aesthetically pleasing feel.
In hair care products such as shampoos, conditioners, and styling products, Cyclopentasiloxane D5 can contribute to improved manageability, shine, and detangling.
Found in various skincare products like creams and lotions, Cyclopentasiloxane D5 helps in providing a smooth application, and its volatility ensures a non-greasy finish.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Cyclopentasiloxane D5 is documented to be an anti-static agent, non-greasy, non-sticky, and is acclaimed for giving a slippery feel and a dry non-cooling sensation on evaporation.
Cyclopentasiloxane D5 evaporates quickly and does not leave behind any residue.
This commands application in formulating deodorants and antiperspirants.
Cyclopentasiloxane D5 makes spreading products a breeze because of its unique fluidity.
Cyclopentasiloxane D5 provides stability to the formulation and prevents it from splitting.
Cyclopentasiloxane D5 is used to deposit active ingredients on the skin and hair, thereby enhancing the efficacy of the formulation.
Cyclopentasiloxane D5 is used in serums, lotions, hair sprays, face and body mists, sunscreens, non-sticky oils, etc.
Cyclopentasiloxane D5 is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom.
Cyclopentasiloxane D5 is used in the production of some silicon-based polymers that are widely used in various personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Featured Industries: Pharmaceutical (small molecule)
Cyclopentasiloxane D5, is a type of silicone commonly used in various personal care and cosmetic products.
Cyclopentasiloxane D5 belongs to the class of cyclic siloxanes, specifically a pentamer of the chemical formula (CH3)2SiO.
The "D5" designation refers to its cyclic structure and is often used in product ingredient lists.
Cyclopentasiloxane D5 is described by Robinson as a silicon-based compound, and it's part of a larger category called cyclomethicone.
Cyclopentasiloxane D5 functions primarily as an emollient, comes in a colorless and odorless liquid form, and is found in a vast array of beauty products from skincare to haircare.
Cyclopentasiloxane D5 is often included in skin care formulations to improve the silky-smooth spreadabilty and sensorial feel of a product.
Cyclopentasiloxane D5 is a lightweight silicone, whose appearance as a raw material is a clear, odorless fluid.
Cyclopentasiloxane D5 also functions as a solvent to help improve the dispersion of cosmetic ingredients in a solution and improve delivery of key ingredients.
Cyclopentasiloxane D5 is a volatile silicone, meaning it evaporates quickly when applied to the skin or hair.
Cyclopentasiloxane D5 is classified as a cyclomethicone.
Such fluids are commonly used in cosmetics, such as deodorants, sunblocks, hair sprays and skin care products.
Cyclopentasiloxane D5 is becoming more common in hair conditioners, as it makes the hair easier to brush without breakage.
Cyclopentasiloxane D5 is also used as part of silicone-based personal lubricants.
Cyclopentasiloxane D5 is considered an emollient.
Cyclopentasiloxane D5 is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom.
Cyclopentasiloxane D5 is used in the production of some silicon-based polymers that are widely used in various personal care products.
Cyclopentasiloxane D5 is a staple ingredient used in cosmetics.
The chemical formula for Cyclopentasiloxane D5 is C10H30O5Si5.
Cyclopentasiloxane D5 is a non-greasy silicone that is colorless, odorless, and water-thin.
Cyclopentasiloxane D5 is a high molecular weight, hydrophobic silicone fluid with a low vapor pressure.
Cyclopentasiloxane D5 gets quickly evaporated from the skin rather than getting absorbed - making it a brilliant ingredient to be used in products that need to dry fast, like antiperspirants and hair sprays.
Cyclopentasiloxane D5 is categorise as a volatile silicone, but it’s important to distinguish that the word volatile here doesn’t mean irritating to skin.
Instead, Cyclopentasiloxane D5 means this kind of silicone evaporates quickly from skin’s surface, which is one of the advantages of formulating with Cyclopentasiloxane D5 as it is able to evenly distribute other key ingredients without leaving a heavy or occlusive feel.
The velvety film left behind is permeable, meaning Cyclopentasiloxane D5 doesn’t suffocate skin.
Further, Cyclopentasiloxane D5 also has lubricating properties and feels silky smooth when applied to hair and skin.
These Secondary Standards are qualified as Certified Reference Materials.
Cyclopentasiloxane D5 is a volatile polydimethylcyclosiloxane composed mainly of Cyclopentasiloxane D5.
These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Cyclopentasiloxane D5 is preferred for its conditioning, viscosity controlling, and water-repelling properties.
Cyclopentasiloxane D5 is an excellent solvent and can be found in countless products.
In Canada, among the volume used in consumer products approximately 70% were for antiperspirants and 20% for hair care products.
10,000–100,000 tonnes per year of Cyclopentasiloxane D5 is manufactured and/or imported in the European Economic Area.
Atmospheric emissions of D5 in the Northern Hemisphere were estimated to 30,000 tonnes per year.
Cyclopentasiloxane D5 may be used as a pharmaceutical reference standard for the determination of the analyte in personal care formulations by gas chromatography.
From this mixture, the cyclic siloxanes including D5 can be removed by distillation.
Cyclopentasiloxane D5, also known as D5, is an organosilicon compound with the formula [(CH3)2SiO]5.
Cyclopentasiloxane D5 is used as a reactive diluent in the synthesis of compounds that have an unsaturated bond.
Cyclopentasiloxane D5 can also be used as a film-forming polymer in cosmetics and personal care products, such as hair sprays, body lotions, and antiperspirants.
Cyclopentasiloxane D5 is used in the synthesis of butanediol, which is then converted into other materials like polyester or polysiloxanes.
Cyclopentasiloxane D5 is a colorless and odorless liquid that is slightly volatile.
Cyclopentasiloxane D5 has a high resistance to hydrolysis by water and acids.
Cyclopentasiloxane D5 is used in the production of some silicon-based polymers that are widely used in various personal care products.
Cyclopentasiloxane D5 is produced from dimethyldichlorosilane.
Hydrolysis of the dichloride produces a mixture of cyclic Cyclopentasiloxane D5 and polydimethylsiloxane.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Cyclopentasiloxane D5 was marketed as a more environmentally friendly solvent than tetrachloroethylene (the most common dry-cleaning solvent worldwide) despite being controlled in the EU for to its persistent, bioaccumulative and toxic characteristic.
Cyclopentasiloxane D5 has also been tried as a dry-cleaning solvent in the early 2000s.
Cyclopentasiloxane D5 is suspected of being an endocrine disruptor and a pollutant through accumulation and persistence in the environment.
Cyclopentasiloxane D5 is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom.
Melting point: -44°C
Boiling point: 90 °C/10 mmHg (lit.)
Density: 0.958 g/mL at 25 °C (lit.)
vapor pressure: 33.2Pa at 25℃
refractive index: n20/D 1.396(lit.)
Flash point: 162 °F
storage temp.: 2-8°C
solubility: <0.0001g/l (calculated)
form: Liquid
color: Colorless
Specific Gravity: 0.959
explosive limit 0.52-7%(V)
Water Solubility: Immiscible with water.
Hydrolytic Sensitivity 1: no significant reaction with aqueous systems
Merck: 14,2848
BRN: 1800166
Dielectric constant: 2.5（20℃）
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey: XMSXQFUHVRWGNA-UHFFFAOYSA-N
LogP: 8.07 at 24.6℃
Cyclopentasiloxane D5 is practically insoluble in water, but miscible with alcohols and other solvents .
Cyclopentasiloxane D5 works by carrying the key ingredients of a formulation into the skin and hair for better absorption.
Lacking penetrative powers, Cyclopentasiloxane D5 simply forms a layer over the skin.
Cyclopentasiloxane D5 makes the surface slippery and then evaporates owing to its volatility.
Cyclopentasiloxane D5 is insoluble in water and is soluble in alcohols, silicones, and solvents.
Cyclopentasiloxane D5 evaporates easily, even from cosmetics, without cooling or causing any discomfort.
D5 is classified as a hazardous substance due to suspected reproductive toxic effects .
D5 and Cyclopentasiloxane D5 are difficult to degrade and accumulate in living organisms (bioaccumulating).
With D5 and Cyclopentasiloxane D5, there is a risk that they will find their way into the human organism through inhalation as a volatile substance from cosmetics.
Cyclopentasiloxane D5 was introduced into cosmetics in 1978.
Cyclopentasiloxane D5 is a volatile fluid with appreciable vapor pressure at ambient temperature.
Cyclopentasiloxane D5 is suspected of being an endocrine disruptor and environmental pollutant because it accumulates in the environment and is persistent.
Cyclopentasiloxane D5 is suggested that its concentration be kept between 3%-10% for deodorants and skin care products, though it can be increased up to 20%.
Cyclopentasiloxane D5s, are inert synthetic polymers consisting of repeated units of silicon (Si) atoms, oxygen atoms (O), and R organic substituent (R2SiO), occurring in linear or cyclic forms.
Based on their polymer length, particle size, and molecular weights, siloxanes can be categorised into different groups: fluids, elastomers and resins.
Cyclopentasiloxane D5’s also used as a sealant to protect the skin against moisture loss and as a lubricant as it helps the skin and hair absorb heavier, larger molecular weight ingredients.
Cyclopentasiloxane D5 gives products a silky, smooth feel that then have a nice feel to the skin.
Also known as Cyclopentasiloxane D5, thankfully, it’s often referred to as simply, D5.
Cyclopentasiloxane D5’s colourless, odourless and is always found in liquid form.
Cyclopentasiloxane D5 is a polydimethylcyclosiloxane that is composed of DecamethylCyclopentasiloxane D5 (CAS# 541‐02‐6).
Cyclopentasiloxane D5 is clear, tasteless, essentially odorless, non‐greasy and non‐stinging.
Due to their varying rates of evaporation, low surface tensions (high spreadability), and non‐greasy feel, Cyclopentasiloxane D5s are used as base fluids, carrying agents and wetting agents in a wide range of personal care products.
Cosmetic applications include: room sprays, body sprays, antiperspirants, skin creams, skin lotions, suntan lotions, bath oils, hair care products etc.
Cyclopentasiloxane D5 Fluids are California VOC Exempt and will not contribute to ozone‐ depletion and global warming.
They are being uses as replacements for Non‐VOC compliant petroleum‐bases solvents as both carrying agents as well as for cleaning solvents where low to medium solvency power is desireable.
Both Cyclo‐2244 and Cyclo‐2245 have comparable evaporation rates to naptha solvents, odorless mineral spirits (OMS) as well as some of the isoparaffinic solvents.
They are compatible with most substates, including metals and plastics.
Cyclopentasiloxane D5 consists of fully methylated cyclic dimethylpolysiloxanes such as octamethylcyclotetrasiloxane (D4), decamethylCyclopentasiloxane D5 (D5) and dodecamethylcyclohexasiloxane (D6), although the exact composition varies.
Uses Of Cyclopentasiloxane D5:
Cyclopentasiloxane D5 is used in the production of polymers and plastics to improve processing and molding properties.
Included in certain paint and coating formulations for its ability to enhance the texture and application of the product.
Cyclopentasiloxane D5 is used in some electronic and electrical insulation materials for its dielectric properties.
Applied as a release agent in molding processes to facilitate the easy removal of molded products.
Cyclopentasiloxane D5 sometimes appears on a label as decamethylCyclopentasiloxane D5 or D5.
Cyclopentasiloxane D5 may also be put under the broader category name of cyclomethicone.
Cyclopentasiloxane D5’s different from another siloxane known as dimethicone or polydimethylsiloxane (PDMS).
Cyclopentasiloxane D5 is classified as a cyclomethicone.
Such fluids are commonly used in cosmetics, such as deodorants, sunblocks, hair sprays and skin care products.
Cyclopentasiloxane D5 is becoming more common in hair conditioners, as it makes the hair easier to brush without breakage.
Cyclopentasiloxane D5 is also used as part of silicone-based personal lubricants.
Cyclopentasiloxane D5 is considered an emollient.
In Canada, among the volume used in consumer products approximately 70% were for antiperspirants and 20% for hair care products.
10,000–100,000 tonnes per year of Cyclopentasiloxane D5 is manufactured and/or imported in the European Economic Area.
Atmospheric emissions of Cyclopentasiloxane D5 in the Northern Hemisphere were estimated to 30,000 tonnes per year.
Found in moisturizers, creams, and lotions to provide a smooth and silky texture.
Cyclopentasiloxane D5 is used in anti-aging products to improve the spreadability and application of active ingredients.
Included in shampoos and conditioners to enhance manageability, detangling, and shine.
Cyclopentasiloxane D5 is used in styling products such as serums and hair sprays for a lightweight, non-greasy finish.
Found in various cosmetics, including foundations, primers, and concealers, to improve texture and blendability.
Cyclopentasiloxane D5 is used in lip products for a smooth application.
Included in sunscreens to enhance the spreadability of the product and provide a pleasant feel on the skin.
Cyclopentasiloxane D5 is used in formulations to improve the texture and application of deodorant products.
Found in certain pharmaceutical formulations and medical creams for its emollient properties.
Cyclopentasiloxane D5 is used in various industrial applications where a silicone with specific properties is required.
May be found in certain household products for its lubricating and water-repelling characteristics.
Applied in textile finishing processes to enhance fabric softness and improve the feel of textiles.
Cyclopentasiloxane D5 is used in certain personal lubricants for its smooth and non-sticky properties.
Included in certain automotive and metal polishes to improve the application and shine.
They are also known to form a protective barrier on the skin and hair.
Cyclopentasiloxane D5 can help detangle your hair, prevent breakage, and reduce frizz.
Employed as an antifoaming agent in various industrial processes where foam formation needs to be controlled.
Cyclopentasiloxane D5 is used in certain adhesive and sealant formulations to improve spreading and application properties.
Included in leather care products such as polishes and conditioners for its conditioning and shining properties.
Found in certain household and cleaning products to enhance the formulation's spreadability and texture.
Cyclopentasiloxane D5 is used in certain automotive care products like dashboard polishes and interior cleaners for its smoothing and conditioning effects.
Cyclopentasiloxane D5 is incorporated into a formulation for its emollient and solvent activity.
A cyclic volatile methylsiloxane (cVMS) used in cosmetic and personal care products.
Cyclopentasiloxane D5 is used in dermal exposure and inhalation toxicity study.
Octamethylcyclotetrasiloxane and Cyclopentasiloxane D5 are major industrial products, which are either marketed as such or used for the production of polydimethylsiloxanes.
Cyclopentasiloxane D5 used in cosmetic and personal care products.
Cyclopentasiloxane D5 used in dermal exposure and inhalation toxicity study.
Intermediate in the manufacture of high mol wt siloxane polymers.
Carrier ingredient in personal care products; dry cleaning solvent.
Cyclopentasiloxane D5 is incorporated into a formulation for its emollient and solvent activity.
Octamethylcyclotetrasiloxane and Cyclopentasiloxane D5 are major industrial products, which are either marketed as such or used for the production of polydimethylsiloxanes.
Cyclopentasiloxane D5 is known for being able to evaporate and dry quickly.
Intermediate in the manufacture of high mol wt siloxane polymers.
Cyclopentasiloxane D5 are also known to repel water and glide easily.
Cyclopentasiloxane D5 is why they are commonly used as ingredients in lubricants and sealants.
Safety Profile Of Cyclopentasiloxane D5:
Cyclopentasiloxane D5 by the Australian government stated, "the direct risks to aquatic life from exposure to these chemicals at expected surface water concentrations are not likely to be significant."
The environmental impacts of Cyclopentasiloxane D5 and D4 have attracted attention because these compounds are pervasive.
Cyclic siloxanes have been detected in some species of aquatic life.
However, in the European Union, Cyclopentasiloxane D5 was characterized as a substance of very high concern (SVHC) due to its PBT and vPvB properties and was thus included in the candidate list for authorisation.
Since 31 January 2020, Cyclopentasiloxane D5 cannot be placed on the market in the European Union in wash-off cosmetic products in a concentration equal to or greater than 0.1 % by weight.
A scientific review in Canada has determined that “Siloxane D5 does not pose a danger to the environment” and a scientific assessment of
