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Cyclopentasiloxane (D5) has also been tried as a dry-cleaning solvent in the early 2000s.
Cyclopentasiloxane (D5) helps in the even distribution of other ingredients in formulations.
Cyclopentasiloxane (D5) acts as an emollient, imparting a soft and smooth texture to the skin or hair.
CAS Number: 541-02-6
Molecular Formula: C10H30O5Si5
Molecular Weight: 370.77
EINECS Number: 208-764-9
Synonyms: DECAMETHYLCyclopentasiloxane (D5), 541-02-6, Cyclopentasiloxane (D5), decamethyl-, Cyclomethicone 5, 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane, Cyclopentasiloxane (D5), Dimethylsiloxane pentamer, Dekamethylcyklopentasiloxan, Dow corning 345, NUC silicone VS 7158, Silicon SF 1202, Ciclopentasiloxane, Cyclic dimethylsiloxane pentamer, Cyclomethicone D5, D5-sil, KF 995, CCRIS 1328, VS 7158, HSDB 5683, UNII-0THT5PCI0R, 0THT5PCI0R, EINECS 208-764-9, SF 1202, BRN 1800166, DTXSID1027184, JEESILC CPS-211, XIAMETER PMX-0245, DTXCID907184, Cyclopentasiloxane (D5) (D5), D5, EC 208-764-9, 4-04-00-04128 (Beilstein Handbook Reference), KF-995, DOW CORNING ST CYCLOMETHICONE 5, OCTAMETHYLCYCLOTETRASILOXANE (D5), KP-545 COMPONENT CYCLOMETHICONE 5, 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane, Cyclopentasiloxane (D5), 2,2,4,4,6,6,8,8,10,10-decamethyl-, CYCLOMETHICONE 5 (USP-RS), CYCLOMETHICONE 5 [USP-RS], MFCD00046966, Dekamethylcyklopentasiloxan [Czech], DdecamethylCyclopentasiloxane (D5), decamethyl Cyclopentasiloxane (D5), C10H30O5Si5, Lightening Serum, Cyclopentasiloxane (D5), dimethylCyclopentasiloxane (D5), Decamethylcylopentasiloxane, UNII: 0THT5PCI0R, SCHEMBL28497, N-Propylheptamethyltrisiloxane, CHEMBL1885178, Cyclopentasiloxane (D5) [INCI], 3CE PINK IM GOOD MASCARA, CHEBI:191092, DecamethylCyclopentasiloxane (D5), 97%, XMSXQFUHVRWGNA-UHFFFAOYSA-N, CYCLOMETHICONE 5 [WHO-DD], BCP15826, Tox21_303170, CD3770, Cyclopentasiloxane (D5), DECAMETHYL, AKOS008901199, CS-W009767, DB11244, HY-W009051, DECAMETHYLCyclopentasiloxane (D5) [MI], NCGC00163981-01, NCGC00257224-01, AS-59731, CAS-541-02-6, DECAMETHYLCyclopentasiloxane (D5) [HSDB], D1890, D3770, DecamethylCyclopentasiloxane (D5) (cyclic monomer), FT-0665531, NS00043162, D78203, S05475, DecamethylCyclopentasiloxane (D5), analytical standard, Q414350, decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane, Cyclomethicone 5, United States Pharmacopeia (USP) Reference Standard, 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane.
Cyclopentasiloxane (D5) is documented to be an anti-static agent, non-greasy, non-sticky, and is acclaimed for giving a slippery feel and a dry non-cooling sensation on evaporation.
Cyclopentasiloxane (D5) evaporates quickly and does not leave behind any residue.
This commands application in formulating deodorants and antiperspirants.
Cyclopentasiloxane (D5) makes spreading products a breeze because of its unique fluidity.
Cyclopentasiloxane (D5) provides stability to the formulation and prevents it from splitting.
Cyclopentasiloxane (D5) is used to deposit active ingredients on the skin and hair, thereby enhancing the efficacy of the formulation.
Cyclopentasiloxane (D5) is used in serums, lotions, hair sprays, face and body mists, sunscreens, non-sticky oils, etc.
Cyclopentasiloxane (D5) is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom.
Cyclopentasiloxane (D5) is used in the production of some silicon-based polymers that are widely used in various personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Featured Industries: Pharmaceutical (small molecule)
Cyclopentasiloxane (D5), is a type of silicone commonly used in various personal care and cosmetic products.
Cyclopentasiloxane (D5) belongs to the class of cyclic siloxanes, specifically a pentamer of the chemical formula (CH3)2SiO.
The "D5" designation refers to its cyclic structure and is often used in product ingredient lists.
Cyclopentasiloxane (D5) is described by Robinson as a silicon-based compound, and it's part of a larger category called cyclomethicone.
Cyclopentasiloxane (D5) functions primarily as an emollient, comes in a colorless and odorless liquid form, and is found in a vast array of beauty products from skincare to haircare.
Cyclopentasiloxane (D5) is often included in skin care formulations to improve the silky-smooth spreadabilty and sensorial feel of a product.
Cyclopentasiloxane (D5) is a lightweight silicone, whose appearance as a raw material is a clear, odorless fluid.
Cyclopentasiloxane (D5) also functions as a solvent to help improve the dispersion of cosmetic ingredients in a solution and improve delivery of key ingredients.
Cyclopentasiloxane (D5) is a volatile silicone, meaning it evaporates quickly when applied to the skin or hair.
Cyclopentasiloxane (D5) is classified as a cyclomethicone.
Such fluids are commonly used in cosmetics, such as deodorants, sunblocks, hair sprays and skin care products.
Cyclopentasiloxane (D5) is becoming more common in hair conditioners, as it makes the hair easier to brush without breakage.
Cyclopentasiloxane (D5) is also used as part of silicone-based personal lubricants.
Cyclopentasiloxane (D5) is considered an emollient.
Cyclopentasiloxane (D5) is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom.
Cyclopentasiloxane (D5) is used in the production of some silicon-based polymers that are widely used in various personal care products.
Cyclopentasiloxane (D5) is a staple ingredient used in cosmetics.
The chemical formula for Cyclopentasiloxane (D5) is C10H30O5Si5.
Cyclopentasiloxane (D5) is a non-greasy silicone that is colorless, odorless, and water-thin.
Cyclopentasiloxane (D5) is a high molecular weight, hydrophobic silicone fluid with a low vapor pressure.
Cyclopentasiloxane (D5) gets quickly evaporated from the skin rather than getting absorbed - making it a brilliant ingredient to be used in products that need to dry fast, like antiperspirants and hair sprays.
Cyclopentasiloxane (D5) is categorise as a volatile silicone, but it’s important to distinguish that the word volatile here doesn’t mean irritating to skin.
Instead, Cyclopentasiloxane (D5) means this kind of silicone evaporates quickly from skin’s surface, which is one of the advantages of formulating with Cyclopentasiloxane (D5) as it is able to evenly distribute other key ingredients without leaving a heavy or occlusive feel.
The velvety film left behind is permeable, meaning Cyclopentasiloxane (D5) doesn’t suffocate skin.
Further, Cyclopentasiloxane (D5) also has lubricating properties and feels silky smooth when applied to hair and skin.
These Secondary Standards are qualified as Certified Reference Materials.
Cyclopentasiloxane (D5) is a volatile polydimethylcyclosiloxane composed mainly of Cyclopentasiloxane (D5).
These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Cyclopentasiloxane (D5) is preferred for its conditioning, viscosity controlling, and water-repelling properties.
Cyclopentasiloxane (D5) is an excellent solvent and can be found in countless products.
In Canada, among the volume used in consumer products approximately 70% were for antiperspirants and 20% for hair care products.
10,000–100,000 tonnes per year of Cyclopentasiloxane (D5) is manufactured and/or imported in the European Economic Area.
Atmospheric emissions of D5 in the Northern Hemisphere were estimated to 30,000 tonnes per year.
Cyclopentasiloxane (D5) may be used as a pharmaceutical reference standard for the determination of the analyte in personal care formulations by gas chromatography.
Cyclopentasiloxane (D5) is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom.
Cyclopentasiloxane (D5) is used in the production of some silicon-based polymers that are widely used in various personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Cyclopentasiloxane (D5) is a silicone regularly used in cosmetic products.
Cyclopentasiloxane (D5)’s commonly found in medical implants, sealants, lubricants, and windshield coatings.
Cyclopentasiloxane (D5) is colorless, odorless, non-greasy, and water-thin.
Cyclopentasiloxane (D5) doesn’t get absorbed into the skin.
Rather, Cyclopentasiloxane (D5) evaporates quickly away from it.
This property makes Cyclopentasiloxane (D5) a useful ingredient in cosmetic products that need to dry quickly, like antiperspirants and hair sprays.
Cyclopentasiloxane (D5) also has lubricating properties.
This gives a slippery and silky feeling when applied to the skin and hair and allows Cyclopentasiloxane (D5) to spread more easily.
As if the name "Cyclopentasiloxane (D5)" wasn't hard enough to say, we should point out that it's also known as decamethylCyclopentasiloxane (D5).
This property contributes to a smooth and lightweight feel upon application.
Cyclopentasiloxane (D5) enhances the spreadability of cosmetic products and provides a silky, non-greasy texture.
Cyclopentasiloxane (D5), also known as D5, is an organosilicon compound with the formula [(CH3)2SiO]5.
Cyclopentasiloxane (D5) is used as a reactive diluent in the synthesis of compounds that have an unsaturated bond.
Cyclopentasiloxane (D5) can also be used as a film-forming polymer in cosmetics and personal care products, such as hair sprays, body lotions, and antiperspirants.
Cyclopentasiloxane (D5) is used in the synthesis of butanediol, which is then converted into other materials like polyester or polysiloxanes.
Cyclopentasiloxane (D5) is a colorless and odorless liquid that is slightly volatile.
Cyclopentasiloxane (D5) has a high resistance to hydrolysis by water and acids.
Cyclopentasiloxane (D5) can improve the appearance of cosmetic formulations, giving them a luxurious and aesthetically pleasing feel.
Cyclopentasiloxane (D5) was marketed as a more environmentally friendly solvent than tetrachloroethylene (the most common dry-cleaning solvent worldwide) despite being controlled in the EU for to its persistent, bioaccumulative and toxic characteristic.
Cyclopentasiloxane (D5) is produced from dimethyldichlorosilane.
Hydrolysis of the dichloride produces a mixture of cyclic Cyclopentasiloxane (D5) and polydimethylsiloxane.
From this mixture, the cyclic siloxanes including D5 can be removed by distillation.
Cyclopentasiloxane (D5) is suspected of being an endocrine disruptor and a pollutant through accumulation and persistence in the environment.
In hair care products such as shampoos, conditioners, and styling products, Cyclopentasiloxane (D5) can contribute to improved manageability, shine, and detangling.
Found in various skincare products like creams and lotions, Cyclopentasiloxane (D5) helps in providing a smooth application, and its volatility ensures a non-greasy finish.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Melting point: -44°C
Boiling point: 90 °C/10 mmHg (lit.)
Density: 0.958 g/mL at 25 °C (lit.)
vapor pressure: 33.2Pa at 25℃
refractive index: n20/D 1.396(lit.)
Flash point: 162 °F
storage temp.: 2-8°C
solubility: <0.0001g/l (calculated)
form: Liquid
color: Colorless
Specific Gravity: 0.959
explosive limit 0.52-7%(V)
Water Solubility: Immiscible with water.
Hydrolytic Sensitivity 1: no significant reaction with aqueous systems
Merck: 14,2848
BRN: 1800166
Dielectric constant: 2.5（20℃）
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey: XMSXQFUHVRWGNA-UHFFFAOYSA-N
LogP: 8.07 at 24.6℃
Cyclopentasiloxane (D5)’s also used as a sealant to protect the skin against moisture loss and as a lubricant as it helps the skin and hair absorb heavier, larger molecular weight ingredients.
Cyclopentasiloxane (D5) gives products a silky, smooth feel that then have a nice feel to the skin.
Also known as Cyclopentasiloxane (D5), thankfully, it’s often referred to as simply, D5.
Cyclopentasiloxane (D5)’s colourless, odourless and is always found in liquid form.
Cyclopentasiloxane (D5) is a polydimethylcyclosiloxane that is composed of DecamethylCyclopentasiloxane (D5) (CAS# 541‐02‐6).
Cyclopentasiloxane (D5) is clear, tasteless, essentially odorless, non‐greasy and non‐stinging.
Due to their varying rates of evaporation, low surface tensions (high spreadability), and non‐greasy feel, Cyclopentasiloxane (D5)s are used as base fluids, carrying agents and wetting agents in a wide range of personal care products.
Cosmetic applications include: room sprays, body sprays, antiperspirants, skin creams, skin lotions, suntan lotions, bath oils, hair care products etc.
Cyclopentasiloxane (D5) Fluids are California VOC Exempt and will not contribute to ozone‐ depletion and global warming.
They are being uses as replacements for Non‐VOC compliant petroleum‐bases solvents as both carrying agents as well as for cleaning solvents where low to medium solvency power is desireable.
Both Cyclo‐2244 and Cyclo‐2245 have comparable evaporation rates to naptha solvents, odorless mineral spirits (OMS) as well as some of the isoparaffinic solvents.
They are compatible with most substates, including metals and plastics.
Cyclopentasiloxane (D5) consists of fully methylated cyclic dimethylpolysiloxanes such as octamethylcyclotetrasiloxane (D4), decamethylCyclopentasiloxane (D5) (D5) and dodecamethylcyclohexasiloxane (D6), although the exact composition varies.
Cyclopentasiloxane (D5) is practically insoluble in water, but miscible with alcohols and other solvents .
Cyclopentasiloxane (D5) works by carrying the key ingredients of a formulation into the skin and hair for better absorption.
Lacking penetrative powers, Cyclopentasiloxane (D5) simply forms a layer over the skin.
Cyclopentasiloxane (D5) makes the surface slippery and then evaporates owing to its volatility.
Cyclopentasiloxane (D5) is insoluble in water and is soluble in alcohols, silicones, and solvents.
Cyclopentasiloxane (D5) evaporates easily, even from cosmetics, without cooling or causing any discomfort.
Cyclopentasiloxane (D5) is classified as a hazardous substance due to suspected reproductive toxic effects .
D4 and Cyclopentasiloxane (D5) are difficult to degrade and accumulate in living organisms (bioaccumulating).
With D4 and Cyclopentasiloxane (D5), there is a risk that they will find their way into the human organism through inhalation as a volatile substance from cosmetics.
A layer of D 4 on the skin evaporates within 30 minutes at 25 °C and in 10 minutes at 37 °C.
Cyclopentasiloxane (D5)was introduced into cosmetics in 1978.
Cyclopentasiloxane (D5) is a volatile fluid with appreciable vapor pressure at ambient temperature.
Cyclopentasiloxane (D5) is suspected of being an endocrine disruptor and environmental pollutant because it accumulates in the environment and is persistent.
Cyclopentasiloxane (D5) is suggested that its concentration be kept between 3%-10% for deodorants and skin care products, though it can be increased up to 20%.
Cyclopentasiloxane (D5)s, are inert synthetic polymers consisting of repeated units of silicon (Si) atoms, oxygen atoms (O), and R organic substituent (R2SiO), occurring in linear or cyclic forms.
Uses Of Cyclopentasiloxane (D5):
Cyclopentasiloxane (D5) is used in dermal exposure and inhalation toxicity study.
Octamethylcyclotetrasiloxane and Cyclopentasiloxane (D5) are major industrial products, which are either marketed as such or used for the production of polydimethylsiloxanes.
Cyclopentasiloxane (D5) used in cosmetic and personal care products.
Cyclopentasiloxane (D5) used in dermal exposure and inhalation toxicity study.
Intermediate in the manufacture of high mol wt siloxane polymers.
Carrier ingredient in personal care products; dry cleaning solvent.
Cyclopentasiloxane (D5) is incorporated into a formulation for its emollient and solvent activity.
Octamethylcyclotetrasiloxane and Cyclopentasiloxane (D5) are major industrial products, which are either marketed as such or used for the production of polydimethylsiloxanes.
Cyclopentasiloxane (D5) is known for being able to evaporate and dry quickly.
Intermediate in the manufacture of high mol wt siloxane polymers.
Cyclopentasiloxane (D5) are also known to repel water and glide easily.
Cyclopentasiloxane (D5) is why they are commonly used as ingredients in lubricants and sealants.
Cyclopentasiloxane (D5) is used in the production of polymers and plastics to improve processing and molding properties.
Included in certain paint and coating formulations for its ability to enhance the texture and application of the product.
Cyclopentasiloxane (D5) is used in some electronic and electrical insulation materials for its dielectric properties.
Applied as a release agent in molding processes to facilitate the easy removal of molded products.
Cyclopentasiloxane (D5) sometimes appears on a label as decamethylCyclopentasiloxane (D5) or D5.
Cyclopentasiloxane (D5) may also be put under the broader category name of cyclomethicone.
Cyclopentasiloxane (D5)’s different from another siloxane known as dimethicone or polydimethylsiloxane (PDMS).
Cyclopentasiloxane (D5) is classified as a cyclomethicone.
Such fluids are commonly used in cosmetics, such as deodorants, sunblocks, hair sprays and skin care products.
Cyclopentasiloxane (D5) is becoming more common in hair conditioners, as it makes the hair easier to brush without breakage.
Cyclopentasiloxane (D5) is also used as part of silicone-based personal lubricants.
Cyclopentasiloxane (D5) is considered an emollient.
In Canada, among the volume used in consumer products approximately 70% were for antiperspirants and 20% for hair care products.
10,000–100,000 tonnes per year of Cyclopentasiloxane (D5) is manufactured and/or imported in the European Economic Area.
Atmospheric emissions of Cyclopentasiloxane (D5) in the Northern Hemisphere were estimated to 30,000 tonnes per year.
Found in moisturizers, creams, and lotions to provide a smooth and silky texture.
Cyclopentasiloxane (D5) is used in anti-aging products to improve the spreadability and application of active ingredients.
Included in shampoos and conditioners to enhance manageability, detangling, and shine.
Cyclopentasiloxane (D5) is used in styling products such as serums and hair sprays for a lightweight, non-greasy finish.
Found in various cosmetics, including foundations, primers, and concealers, to improve texture and blendability.
Cyclopentasiloxane (D5) is used in lip products for a smooth application.
Included in sunscreens to enhance the spreadability of the product and provide a pleasant feel on the skin.
Cyclopentasiloxane (D5) is used in formulations to improve the texture and application of deodorant products.
Found in certain pharmaceutical formulations and medical creams for its emollient properties.
Cyclopentasiloxane (D5) is used in various industrial applications where a silicone with specific properties is required.
May be found in certain household products for its lubricating and water-repelling characteristics.
Applied in textile finishing processes to enhance fabric softness and improve the feel of textiles.
Cyclopentasiloxane (D5) is used in certain personal lubricants for its smooth and non-sticky properties.
Included in certain automotive and metal polishes to improve the application and shine.
They are also known to form a protective barrier on the skin and hair.
Cyclopentasiloxane (D5) can help detangle your hair, prevent breakage, and reduce frizz.
Employed as an antifoaming agent in various industrial processes where foam formation needs to be controlled.
Cyclopentasiloxane (D5) is used in certain adhesive and sealant formulations to improve spreading and application properties.
Included in leather care products such as polishes and conditioners for its conditioning and shining properties.
Found in certain household and cleaning products to enhance the formulation's spreadability and texture.
Cyclopentasiloxane (D5) is used in certain automotive care products like dashboard polishes and interior cleaners for its smoothing and conditioning effects.
Cyclopentasiloxane (D5) is incorporated into a formulation for its emollient and solvent activity.
Safety Profile Of Cyclopentasiloxane (D5):
Cyclopentasiloxane (D5) cannot be placed on the market in the European Union in wash-off cosmetic products in a concentration equal to or greater than 0.1 % by weight.
A scientific review in Canada has determined that “Siloxane D5 does not pose a danger to the environment” and a scientific assessment of D5 by the Australian government stated, "the direct risks to aquatic life from exposure to these chemicals at expected surface water concentrations are not likely to be significant."
The environmental impacts of Cyclopentasiloxane (D5) and D4 have attracted attention because these compounds are pervasive.
Cyclic siloxanes have been detected in some species of aquatic life.
However, in the European Union, Cyclopentasiloxane (D5) was characterized as a substance of very high concern (SVHC) due to its PBT and vPvB properties and was thus included in the candidate list for authorisation.
