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Cyclotetrasiloxane (D4) are clear, odorless liquids utilized in skincare products to give your skincare a smooth texture that allows the product’s key ingredients to be delivered evenly to the skin.
Cyclotetrasiloxane (D4) are part of the silicone family and are used in a similar way to dimethicone, which you may be familiar with.
Cyclotetrasiloxane (D4) help smooth the texture of products, improve the appearance of scarring, increase the waterresistance abilities of formulations, and emulsify the product.
CAS Number: 540976
Molecular Formula: C12H36O6Si6
Molecular Weight: 444.92
EINECS Number: 2087628
Synonyms: Cyclotetrasiloxane (D4), 540976, Cyclotetrasiloxane (D4) dodecamethyl, Cyclomethicone 6, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane, XHK3U310BA, 2,2,4,4,6,6,8,8,10,10,12,12-Cyclotetrasiloxane (D4), EINECS 2087628, UNII-XHK3U310BA, HSDB 7723, EC 2087628, dodecamethyl Cyclotetrasiloxane (D4), SCHEMBL93785, XIAMETER PMX-0246, CYCLOHEXASILOXANE [INCI], DTXSID6027183, IUMSDRXLFWAGNT-UHFFFAOYSA, CHEBI:191103, IUMSDRXLFWAGNT-UHFFFAOYSAN, CYCLOMETHICONE 6 [USPRS], MFCD00144215, AKOS015839990, FS5671, Cyclotetrasiloxane (D4) [MI], Cyclotetrasiloxane (D4) [HSDB], D2040, Cyclotetrasiloxane (D4) [WHODD], FT0625566, S08515, T71035, Cyclotetrasiloxane (D4) analytical standard, A914553, Q27293843, 2,2,4,4,6,6,8,8,10,10,12,12-Cyclotetrasiloxane (D4) #, Cyclotetrasiloxane (D4) 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl, 2,2,4,4,6,6,8,8,10,10,12,12-Cyclotetrasiloxane (D4) 95%, 2,2,4,4,6,6,8,8,10,10,12,12-Cyclotetrasiloxane (D4) Aldrich CPR, Cyclomethicone 6 USP Reference Standard, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexa, D6.
Cyclotetrasiloxane (D4), also known as D4 or simply 'siloxane,' is a chemical compound belonging to the class of organosilicon compounds.
Cyclotetrasiloxane (D4) is a common ingredient in skincare and body care products, used to improve the texture of formulations.
While the texture is usually a sensory aspect of the product, in the case of Cyclotetrasiloxane (D4), it helps the product to be evenly distributed so the key ingredients can improve the skin.
Cyclotetrasiloxane (D4) also has the added benefit of acting as a protective barrier to the skin, protecting the skin from moisture loss, allergens, and bacteria.
Cyclotetrasiloxane (D4) is a type of silicone.
Silicones are synthetic polymers with a backbone composed of repeating units of siloxane, which is why silicones may also be referred to as polysiloxanes.
Siloxane is made up of elemental silicon and oxygen.
Cyclotetrasiloxane (D4) is an organosilicon compound.
Cyclotetrasiloxane (D4), also known as D6, is an industrial chemical.
Cyclotetrasiloxane (D4) is registered under the REACH Regulation and is manufactured in and/or imported to the European Economic Area, at ≥ 1,000 to < 10,000 tonnes per annum.
Cyclotetrasiloxane (D4) is a clear colorless liquid.
There is no known natural source of Cyclotetrasiloxane (D4).
Cyclotetrasiloxane (D4), also known as Cyclotetrasiloxane (D4) or D6, belongs to a group of cyclic volatile methylsiloxanes (cVMS) with relatively low molecular weight (< 600 g/mol) and high vapor pressure.
Cyclotetrasiloxane (D4) contains six repeating units of silicon (Si) and oxygen (O) atoms in a closed loop, giving it a 'cyclic' structure.
The cyclosiloxanes octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), and Cyclotetrasiloxane (D4) (D6) are cyclic volatile methyl siloxane (cVMS) substances with four, five, and six siloxane groups, respectively.
A siloxane is a functional group in organosilicon chemistry with the Si−O−Si linkage.
The parent siloxanes include the oligomeric and polymeric hydrides with the formulae H(OSiH2)nOH and (OSiH2)n.
Siloxanes also include branched compounds, the defining feature of which is that each pair of silicon centres is separated by one oxygen atom.
The siloxane functional group forms the backbone of silicones, the premier example of which is polydimethylsiloxane.
The functional group R3SiO− (where the three Rs may be different) is called siloxy.
Cyclosiloxanes are basic members of the broad family of silicone materials.
All silicone materials share a common chemistry but each substance is different with regard to its properties and use.
D4, D5, and Cyclotetrasiloxane (D4) are the three cyclosiloxanes in commercial production, and their use has been proven safe for human health and the environment.
Cyclotetrasiloxane (D4) is part of a family of small silicones called Cyclotetrasiloxane (D4).
Cyclotetrasiloxane (D4) are also better at delivering active ingredients to the skin as they are more volatile than larger silicones and slowly evaporate from the skin.
When Cyclotetrasiloxane (D4) disappear, they leave behind the formulation’s key ingredients.
Cyclotetrasiloxane (D4) are also known as DodecamethylCyclotetrasiloxane (D4), different names for the same class of molecules.
Cyclotetrasiloxane (D4), more commonly known as DodecamethylCyclotetrasiloxane (D4), contains six repeating units of silicon (Si) and oxygen (O) atoms in a closed loop, giving it a cyclic structure.
When used as an intermediate during the manufacturing process, virtually all Cyclotetrasiloxane (D4) is consumed with only a tiny amount remaining in final products.
Cyclotetrasiloxane (D4)’s structure forms a ring which makes it more volatile or less stable.
This instability allows Cyclotetrasiloxane (D4) to evaporate when applied to your skin readily.
This characteristic makes Cyclotetrasiloxane (D4) a great ingredient for improving the spreadability of products and ensuring they don’t remain sticky after application.
Cyclotetrasiloxane (D4) gradually evaporates from the skin, leaving behind the other key components in the product to improve the appearance of the skin.
This action of evaporation makes it an excellent carrier ingredient.
Cyclotetrasiloxane (D4) belonging to the class of cyclic volatile methylsiloxanes is identified as a potent environmental contaminant, most prominently found in biota, biosolid samples, soil, sediment samples, wastewaters, etc.
Cyclotetrasiloxane (D4) are used as fragrance carriers or solvents in household products, personal care products, cleaning agents and as precursors in the manufacture of silicone polymers.
Cyclotetrasiloxane (D4) is synthetically produced through a chemical process known as cyclotetramerization, where the precursor compound is subjected to high temperatures and catalysts to form the cyclic structure.
This process involves the controlled arrangement of silicon and oxygen atoms to create the Cyclotetrasiloxane (D4) molecule (D6).
The resulting clear, volatile liquid is then purified for use in cosmetics.
A lightfeeling, volatile (meaning it does not absorb into the skin but evaporates from it) silicone that gives skin a unique, silky and nongreasy feel.
Cyclotetrasiloxane (D4) has excellent spreading properties and leaves no oily residue or buildup.
Cyclotetrasiloxane (D4) is one of several forms of synthetic, cyclic (meaning the molecule is circular rather than straight or crosslinked) silicone used in cosmetic formulas to improve texture and enhance skin’s hydration.
Cyclotetrasiloxane (D4) helps give skin care products a silkysmooth, spreadable consistency, so key ingredients can be delivered evenly to skin.
Cyclotetrasiloxane (D4) is also known to promote aesthetically pleasing finishes that don’t feel sticky, tacky or greasy after application.
In hair care, it is used to add shine and reduce frizz.
Cyclotetrasiloxane (D4) is used by consumers, by professional workers (widespread uses), in formulation or repacking, at industrial sites, and in manufacturing.
Cyclotetrasiloxane (D4) is used in the following products: washing & cleaning products, polishes and waxes, and cosmetics and personal care products.
Other release to the environment of Cyclotetrasiloxane (D4) is likely to occur from: indoor use as a processing aid and outdoor use as a processing aid.
Cyclotetrasiloxane (D4) can also be used as an ingredient in silicone mixtures used in cosmetic applications such as skin creams and deodorants.
When Cyclotetrasiloxane (D4) is used as an intermediate during the manufacturing process, virtually all Cyclotetrasiloxane (D4) is consumed with only a tiny amount remaining in final products.
Cyclotetrasiloxane (D4) can also be used as an ingredient in silicone mixtures used in cosmetic applications such as skin creams and sunscreen, where Cyclotetrasiloxane (D4) may be labeled 'DodecamethylCyclotetrasiloxane (D4)'.
Cyclotetrasiloxane (D4) imparts several benefits in personal care formulations, such as silkiness for conditioners, extra volume in lip glosses, and easy application in deodorants.
This product has a Cyclotetrasiloxane (D4) content of 94%.
Cyclosiloxanes are used in the manufacture of silicones, in combination or alone in personal care products, and as carriers, lubricants, and solvents in a variety of commercial applications.
Their use in cosmetics is one of their most important applications.
D5 and Cyclotetrasiloxane (D4) are commonly used in cosmetics as emollients, hair and skin conditioning ingredients, and solvents.
The ingredients can be used in hair conditioning products where the product is washed off when used or in skincare products, personal deodorants, and color cosmetics where the product is left on the skin.
Cyclotetrasiloxane (D4) is used in the following products: cosmetics and personal care products, polishes and waxes, washing & cleaning products, and semiconductors.
Cyclotetrasiloxane (D4) is used in the following areas: health services and formulation of mixtures and/or repackaging.
Cyclotetrasiloxane (D4) is found or used in the manufacture of a wide variety of products.
Cyclotetrasiloxane (D4) is a silicone-based emollient.
A cyclic volatile methylsiloxane (cVMS) used in cosmetic and personal care products, Cyclotetrasiloxane (D4) can be used in dermal exposure and inhalation toxicity study.
Cyclotetrasiloxane (D4)s are used as fragrance carriers or solvents in household products, personal care products, cleaning agents, and as precursors in the manufacture of silicone polymers.
Cyclotetrasiloxane (D4) is used in cosmetic and personal care products.
Cyclotetrasiloxane (D4) is Used in dermal exposure.
Cyclotetrasiloxane (D4) is used in cosmetic and personal care products.
Cyclotetrasiloxane (D4) is used in dermal exposure and inhalation toxicity study.
The most important worldwide use of Cyclotetrasiloxane (D4) is as an ingredient in the formulation of personal care products and as an intermediate in the production of polydimethylsiloxanes (PDMS) silicone polymers.
The predominant use of Cyclotetrasiloxane (D4) worldwide and in Canada is in blending and formulating consumer products and manufacturing silicone polymers.
Cyclotetrasiloxane (D4) is used in personal care products such as hair/skin care products, antiperspirants and deodorants.
Biomedical uses of silicones include medical devices, blood-handling equipment, as a blood defoaming agent, as protective barriers, lubricants, and as surface treatment of wound dressings.
Silicone fluids containing Cyclotetrasiloxane (D4) have also been approved as active and nonactive ingredients in pharmaceuticals in Canada, the most common use being in antiflatulence drugs.
Cyclotetrasiloxane (D4) is also used in industrial processes (as a defoamer, surfactant in certain pesticide products); in lubricants, cleaning products, sealants, adhesives, waxes, polishes, and coatings.
Siloxanes are manmade and have many commercial and industrial applications because of the compounds’ hydrophobicity, low thermal conductivity, and high flexibility.
Cyclotetrasiloxane (D4) is an odorless, colorless liquid mostly used as an intermediate or basic raw material in the production silicone rubbers, gels, and resins.
Cyclotetrasiloxane (D4) can also be used as an ingredient in silicone mixtures used in cosmetic applications such as skin creams and deodorants, where D6 Siloxane may be labeled Cyclotetrasiloxane (D4).
In personal care products, cyclosiloxanes act as 'carriers,' allowing products to spread smoothly and easily and providing a silky feel during application.
Cyclotetrasiloxane (D4) is an odorless, colorless liquid mostly used as an intermediate or basic raw material in the production silicone rubbers, gels, and resins.
As a raw material, Cyclotetrasiloxane (D4) is a colourless liquid.
Cyclotetrasiloxane (D4) is described as a lightweight carrier ingredient since it evaporates from skin, leaving behind the formula’s key ingredients to work effectively.
This ingredient has been deemed safe by the Cosmetic Ingredient Review Expert Panel (their report looked at products using between 0.000448% Cyclotetrasiloxane (D4)).
Cyclotetrasiloxane (D4), as a silicone, improves the feel, appearance, and performance of skincare and cosmetic formulations.
Cyclotetrasiloxane (D4) is a multifunctional ingredient in skincare and cosmetic formulations.
Cyclotetrasiloxane (D4) helps to produce an even, smooth formulation that allows the product to spread evenly over the skin.
Cyclotetrasiloxane (D4) prevents the product from catching on dry skin patches and evens skin tone by gliding over pores and wrinkles.
Cyclotetrasiloxane (D4) ensures that all areas of the skin are receiving the key ingredients in your product.
Cyclotetrasiloxane (D4) is a cyclic siloxane molecule composed of six silicon (Si) atoms alternately bonded to oxygen (O) atoms, forming a ring structure.
The chemical formula for Cyclotetrasiloxane (D4) is typically represented as (SiO1.5)6.
Cyclotetrasiloxane (D4) clear, odorless liquid acts as a light and volatile carrier ingredient that imparts a silky, non-greasy feel to skin care and hair care formulations.
Cyclotetrasiloxane (D4) enhances product spreadability, aids in quick absorption, and provides a smooth, matte finish.
The chemical formula of Cyclotetrasiloxane (D4) is C12H36O6Si6.
Cyclotetrasiloxane (D4) is a silicone-based compound frequently used in cosmetics and personal care products.
Cyclotetrasiloxane (D4) is often utilized alongside other silicones like cyclopentasiloxane to improve the overall texture and performance of cosmetic products.
While cyclopentasiloxane is also commonly used, the choice between the two depends on the specific formulation and desired properties, making them valuable tools in cosmetic science.
Melting point: 3°C
Boiling point: 245 °C
Density: 0,959 g/cm3
vapor pressure: 4.7Pa at 25℃
refractive index: 1.4015
Flash point: >76°C
storage temp.: 28°C
solubility: Chloroform (Sparingly), Ethyl Acetate (Slightly)
form: liquid
color: Colourless
Specific Gravity: 0.9672
Odor: at 100.00?%. odorless
Viscosity: 5.6mm2/s
Water Solubility: 5.1μg/L at 23℃
Hydrolytic Sensitivity 1: no significant reaction with aqueous systems
Merck: 14,3403
Stability: Hygroscopic
LogP: 8.87 at 23.6℃
Cyclotetrasiloxane (D4) also helps to reduce the heaviness of other silicone ingredients.
Synthetic ingredients often have a bad reputation in the skincare world as they are considered not natural.
This plays into the idea that natural is always better, which isn’t always true.
Synthetic ingredients are usually safer than their plant or animalderived counterparts as they contain fewer impurities and are less complex, making them less likely to irritate.
They are also better for the environment as it doesn’t deplete a natural resource.
Cyclotetrasiloxane (D4), along with other Cyclotetrasiloxane (D4), were analyzed in a study published in Skin Pharmacology and Physiology.
Cyclopentasiloxane is a silicone regularly used in cosmetic products.
Cyclotetrasiloxane (D4)’s commonly found in medical implants, sealants, lubricants, and windshield coatings.
Cyclotetrasiloxane (D4) is colorless, odorless, nongreasy, and waterthin.
Cyclotetrasiloxane (D4) doesn’t get absorbed into the skin. Rather, it evaporates quickly away from it.
This property makes it a useful ingredient in cosmetic products that need to dry quickly, like antiperspirants and hair sprays.
Cyclotetrasiloxane (D4) also has lubricating properties.
This gives a slippery and silky feeling when applied to the skin and hair and allows the product to spread more easily.
Cyclomethicone (mixture) and the specific chain length cyclic siloxanes (n = 47) reviewed in this safety assessment are cyclic dimethyl polysiloxane compounds.
These ingredients have the skin/hair conditioning agent function in common.
Silicone compounds D4 (cyclotetrasiloxane), D5 (cyclopentasiloxane), and Cyclotetrasiloxane (D4) are often found in personal care products and flow into the environment along with wastewater.
They are also important source materials for certain silicones and are often found as residues in finished products.
Basic members of the broad family of silicone materials, all cyclotetrasiloxane (D4), cyclopentasiloxane (D5), and Cyclotetrasiloxane (D4) are volatile oils with a cyclic chemical structure and various properties.
They are widely used because of the smooth and refreshing feeling they create.
They are usually present in cosmetic products (makeup, cream, deodorant, etc.) and more widely in certain cleaning products or paints.
Organosiloxanes are widely used in personal care products because they provide desirable properties in cosmetic products.
These compounds are octamethylcyclotetrasiloxane (D4), decamethylcyclotetrasiloxane (D5), and Cyclotetrasiloxane (D4) (D6).
These compounds are cyclic methyl siloxane substances containing four, five, and six siloxane groups, respectively, and they have a mild and refreshing effect in cosmetic products.
Cyclotetrasiloxane (D4) is a volatile substance due to its ringshaped structure.
This allows it to evaporate from the skin, leaving behind the product’s ‘active’ ingredients to work their magic.
Uses:
Cyclotetrasiloxane (D4) is used as a lubricant and anti-foaming agent in industrial processes and machinery.
Cyclotetrasiloxane (D4) may be used in certain pharmaceutical formulations and drug delivery systems.
Cyclotetrasiloxane (D4) serves as a precursor in the synthesis of more complex silicone compounds and polymers, which have a wide range of industrial applications.
Cyclotetrasiloxane (D4) can be used as a solvent in chemical reactions, especially those involving silicon-based compounds.
Cyclotetrasiloxane (D4) can be used in the production of silicone-based polymers, sealants, and coatings due to its ability to crosslink and provide flexibility and resistance to heat and moisture.
Cyclotetrasiloxane (D4) serves as an excellent carrier for other active ingredients in a formulation, aiding in their penetration into the skin.
Its lightweight and noncomedogenic nature makes it ideal for moisturizers, serums, and sunscreens, providing a silky, smooth texture without clogging pores.
By creating a breathable barrier on the skin's surface, Cyclotetrasiloxane (D4) helps in reducing water loss, enhancing hydration, and promoting a soft, supple complexion.
Cyclotetrasiloxane (D4) contributes to smoother and more manageable hair.
Cyclotetrasiloxane (D4) is commonly found in hair serums and conditioners, where it helps detangle and reduce frizz, resulting in silky, lustrous locks.
Due to its low viscosity, it spreads easily through the hair without leaving a heavy or greasy residue.
Cyclotetrasiloxane (D4) also provides heat protection, making it beneficial for use with styling tools, such as flat irons and hairdryers, while minimizing damage and maintaining a sleek, polished appearance
Cyclotetrasiloxane (D4) is found or used in the manufacture of a wide variety of products.
The predominant use of Cyclotetrasiloxane (D4) worldwide and in Canada is in blending and formulating consumer products and manufacturing silicone polymers.
Cyclotetrasiloxane (D4) is used in personal care products such as hair/skin care products, antiperspirants and deodorants.
Biomedical uses of silicones include medical devices, bloodhandling equipment, as a blood defoaming agent, as protective barriers, lubricants and as surface treatment of wound dressings.
Silicone fluids containing D6 have also been approved as active and nonactive ingredients in pharmaceuticals in Canada, the most common use being in antiflatulence drugs.
Cyclotetrasiloxane (D4) is also used in industrial processes (as a defoamer, surfactant in certain pesticide products); in lubricants, cleaning products, sealants, adhesives, waxes, polishes and coatings.
Cyclotetrasiloxane (D4) is not currently manufactured in Canada; however, it is imported into Canada.
Cyclotetrasiloxane (D4) is used in the following products: polymers, washing & cleaning products, laboratory chemicals and polishes and waxes.
Cyclotetrasiloxane (D4) has an industrial use resulting in manufacture of another substance (use of intermediates).
Cyclotetrasiloxane (D4) is used in the following areas: scientific research and development.
Cyclotetrasiloxane (D4) is used for the manufacture of: chemicals.
Release to the environment of Cyclotetrasiloxane (D4) can occur from industrial use: for thermoplastic manufacture, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.
Cyclotetrasiloxane (D4) used in cosmetic and personal care products.
Cyclotetrasiloxane (D4) is used in dermal exposure and inhalation toxicity study.
Cyclotetrasiloxane (D4) can be used in dermal exposure and inhalation toxicity study.
The compound is classified as a Cyclomethicone.
Such fluids are commonly used in cosmetics, such as deodorants, sunblocks, hair sprays, and skin care products.
Cyclotetrasiloxane (D4) is becoming more common in hair conditioners, as it makes the hair easier to brush without breakage.
Cyclotetrasiloxane (D4) is also used as part of silicone-based personal lubricants.
Cyclotetrasiloxane (D4) is considered an emollient.
In Canada, among the volume used in consumer products, approximately 70% were for antiperspirants and 20% for hair care products.
10,000–100,000 tonnes per year of D5 is manufactured and/or imported in the European Economic Area.
Atmospheric emissions of Cyclotetrasiloxane (D4) in the Northern Hemisphere were estimated to be 30,000 tonnes per year.
Such fluids are commonly used in cosmetics, such as deodorants, sunblocks, hair sprays and skin care products.
Cyclotetrasiloxane (D4) is becoming more common in hair conditioners, as it makes the hair easier to brush without breakage.
Cyclotetrasiloxane (D4) is also used as part of siliconebased personal lubricants. D5 is considered an emollient.
Cyclotetrasiloxane (D4) is commonly used in cosmetics, skincare products, and hair care products as a lightweight, volatile silicone.
Cyclotetrasiloxane (D4) can improve the texture and spreadability of creams and lotions, providing a smooth and silky feel to the skin and hair.
Safety Profile:
Cyclic siloxanes have been detected in some species of aquatic life.
A scientific review in Canada has determined that “Siloxane Cyclotetrasiloxane (D4) does not pose a danger to the environment” and a scientific assessment of D5 by the Australian government stated, the direct risks to aquatic life from exposure to these chemicals at expected surface water concentrations are not likely to be significant.
However, in the European Union, Cyclotetrasiloxane (D4) was characterized as a substance of very high concern (SVHC) due to its PBT and vPvB properties and was thus included in the candidate list for authorisation.
Since 31 January 2020, Cyclotetrasiloxane (D4) cannot be placed on the market in the European Union in washoff cosmetic products in a concentration equal to or greater than 0.1 % by weight
Cyclotetrasiloxane (D4) is considered safe for cosmetic use when used as directed.
Cyclotetrasiloxane (D4) has a low potential for skin irritation and is noncomedogenic, making it suitable for most skin types.
However, like many cosmetic ingredients, some individuals with hypersensitive skin may experience mild irritation.
The environmental impacts of Cyclotetrasiloxane (D4) and D4 have attracted attention because these compounds are pervasive.
