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D panthenol (vitamin B5) is widely used to repair damaged hair and promote healing.
D panthenol (vitamin B5) is used in pharmaceutical and children's products as a moisturizer and to hasten wound healing.
D panthenol (vitamin B5) is used in ointments for minor wounds, burns, and skin irritations.
CAS Number: 81-13-0
EC Number: 201-327-3
Molecular Formula: C9H19NO4
Molecular Weight: 205.25 g/mol
SYNONYMS:
2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide[1], Pantothenol, Pantothenyl alcohol, N-Pantoylpropanolamine, Bepanthen (trade name), Dexpanthenol (D form), D-pantothenyl alcohol, pantothenol, dexpanthenol, Dexpanthenol, D-Panthenol, Provitamin B5, Pantothenol, D-Pantothenyl Alcohol, Bepanthene, Panthoderm, Pearl Name: Panthenol, D-Panthenol, Dexpanthenol, Dexpanthenol, Provitamin B5, Pro-Vitamin B5, D-(+)-Panthenol, (R)-Panthenol, Pantothenol, Alcohol Analog of Pantothenic Acid
D-panthenol (vitamin B5) is an essential ingredient in skincare and haircare.
D panthenol (vitamin B5) deeply penetrates tissues, acting as a powerful humectant that seals in moisture, strengthens the skin barrier, and soothes irritation.
D panthenol (vitamin B5), also known as vitamin B5, is an important ingredient found in many cosmetic and dermatological products.
This naturally occurring substance, D panthenol (vitamin B5), is known for its moisturizing, repairing, and protecting properties for skin and hair.
When combined with water, D panthenol (vitamin B5) forms the active form of pantothenic acid (vitamin B5), making it a component essential for many biological functions in the body.
D panthenol (vitamin B5), also known as provitamin B5, is the biologically active alcohol analogue of pantothenic acid (vitamin B5).
D panthenol (vitamin B5) is readily converted in the skin and within living tissues into pantothenic acid, an essential component of coenzyme A (CoA), which plays a vital role in carbohydrate, lipid, and protein metabolism.
D panthenol (vitamin B5) is valued for its ability to improve skin hydration, strengthen the skin barrier, enhance wound healing, reduce irritation, and improve hair condition and shine.
Because of its high safety profile and compatibility with numerous formulation types, D panthenol (vitamin B5) has become one of the most commonly used multifunctional cosmetic ingredients worldwide.
D panthenol (vitamin B5), also known as provitamin B5, is the biologically active alcohol analogue of pantothenic acid (vitamin B5).
D panthenol (vitamin B5) is readily converted in the skin and within living tissues into pantothenic acid, an essential component of coenzyme A (CoA), which plays a vital role in carbohydrate, lipid, and protein metabolism.
Due to its excellent moisturizing, soothing, and regenerative properties, D panthenol (vitamin B5) is widely used in cosmetics, personal care products, pharmaceuticals, dermatological formulations, oral care products, veterinary preparations, and certain food and nutritional applications.
D panthenol (vitamin B5) is valued for its ability to improve skin hydration, strengthen the skin barrier, enhance wound healing, reduce irritation, and improve hair condition and shine.
Because of its high safety profile and compatibility with numerous formulation types, D panthenol (vitamin B5) has become one of the most commonly used multifunctional cosmetic ingredients worldwide.
D panthenol (vitamin B5) is an effective active ingredient widely used in the cosmetics industry.
D panthenol (vitamin B5) is particularly prominent in skin and hair care products for its moisturizing and repairing properties.
D panthenol (vitamin B5) is also quickly absorbed by the skin and has a deep effect.
Therefore, manufacturers prefer to use panthenol in their formulas to ensure both performance and user satisfaction.
D panthenol (vitamin B5) is a versatile ingredient that supports both skin and hair health.
Thanks to its moisturizing, repairing, soothing, and protective properties, D panthenol (vitamin B5) has become an indispensable component in skincare and hair care routines.
Regardless of your skin type, it's possible to achieve a healthy and youthful appearance by using products containing D panthenol (vitamin B5).
D panthenol (vitamin B5) is a more stable version of pantothenic acid (Vitamin B5).
D panthenol (vitamin B5) is a Provitamin B5 (synonyms: D-pantothenyl alcohol, pantothenol, dexpanthenol) and is the alcohol analog of pantothenic acid (vitamin B5).
D panthenol (vitamin B5) penetrates readily into skin & hair.
D panthenol (vitamin B5) has good moisturizing and softening properties.
D panthenol (vitamin B5) soothes irritated and blemished skin.
D panthenol (vitamin B5) gives the hair moisture & shine and reduces split ends.
D panthenol (vitamin B5), also known as pantothenic acid, is a water-soluble B vitamin.
D panthenol (vitamin B5) is one of the essential vitamins for the human body and plays a vital role in cellular metabolic processes.
D panthenol (vitamin B5) is critically important in the production of coenzyme A, which in turn acts as a key component in many biological processes such as energy production, metabolism, and hormone synthesis.
Naturally found in many foods, D panthenol (vitamin B5) makes significant contributions to processes such as energy production, cell renewal, and fatty acid metabolism in the body.
D panthenol (vitamin B5) is an alcohol analog of pantothenic acid, and thus a provitamin of B5.
D panthenol (vitamin B5) is an odorless, transparent, highly viscous, and colorless liquid at room temperature.
D panthenol (vitamin B5) is a form of Pro-D panthenol (vitamin B5) commonly used in skin and hair care.
This water-soluble active ingredient, D panthenol (vitamin B5), penetrates deeply into the skin and hair, providing intense hydration, softening, and irritation relief.
D panthenol (vitamin B5) supports cell regeneration, strengthens the skin barrier, and thickens hair strands, adding shine.
D panthenol (vitamin B5) comes in two enantiomers: D, and L.
Only D panthenol (vitamin B5) is biologically active.
For cosmetic use, D panthenol (vitamin B5) comes either in D form or as a racemic mixture of D and L (DL-panthenol (vitamin B5)).
D panthenol (vitamin B5) is an alcohol analogue of pantothenic acid and is also known as proD panthenol (vitamin B5).
D panthenol (vitamin B5) is a viscous, transparent liquid at room temperature.
D panthenol (vitamin B5) is an effective moisturizing and regenerating ingredient in skin and hair care.
D panthenol (vitamin B5)'s skin-compatible formula locks in moisture, providing softness, reducing irritation, and supporting repair.
D panthenol (vitamin B5) (also called pantothenol) is the alcohol analog of pantothenic acid, and is thus a provitamin of B5.
In organisms, D panthenol (vitamin B5) is quickly oxidized to pantothenic acid.
D panthenol (vitamin B5) is a viscous transparent liquid at room temperature.
D panthenol (vitamin B5) works well on your skin because vitamin B5 is extracted with ethanol or benzyl alcohol to dissolve into your skin.
This type of topical treatment includes other vitamins and amino acids that are good for your skin.
When you put D panthenol (vitamin B5) on your skin, it converts into vitamin B5.
D panthenol (vitamin B5) is then absorbed into your skin.
You are most likely to find D panthenol (vitamin B5) as an ingredient in products as an oil or a creamy white powder (DL-D panthenol (vitamin B5)).
D panthenol (vitamin B5) can be absorbed into the hair and skin and is immediately converted into Pantothenic Acid or D panthenol (vitamin B5).
D panthenol (vitamin B5) is very important for healthy hair and skin.
D panthenol (vitamin B5) moisturizes the skin and hair and reduces inflammation/itching of the skin and scalp.
D panthenol (vitamin B5) (powder type, easily soluble in water) is a substance that can be absorbed into the hair and skin and will be immediately converted to Pantothenic Acid or D panthenol (vitamin B5).
D panthenol (vitamin B5) is very important for healthy hair and skin.
D panthenol (vitamin B5) nourishes the skin, reduces inflammation, reduces redness, reduces itching, helps heal wounds.
D panthenol (vitamin B5) relieves itching from allergies, reduces redness, helps heal wounds and accelerates the creation of new skin tissue, reduces skin inflammation, especially suitable for skin with acne, wounds, itchy rashes, and allergies.
Research has found that D panthenol (vitamin B5) helps extend the life of skin cells (skin cell proliferation), making wounds heal faster and reducing scarring.
An example of use is on skin with acne because D panthenol (vitamin B5) helps both heal wounds, prevents scarring, and reduces redness from acne.
In addition, D panthenol (vitamin B5) can nourish hair health, moisturize hair and make hair strong and shiny.
D panthenol (vitamin B5) is suitable for all types of hair care products.
D panthenol (vitamin B5) is a stable racemic mixture of D-Panthenol and L-Panthenol.
The human body readily absorbs DL-Panthenol through the skin and it rapidly converts D-Panthenol to Pantothenic Acid (D panthenol (vitamin B5)), a natural constituent of healthy hair and a substance present in all living cells.
When D panthenol (vitamin B5) comes to moisturization properties- improved hydration, reducing water loss and maintaining skin elasticity and softness- this racemic mixture is 100% active.
When applied for skin epithelization (wound healing), only D-Panthenol is converted to D panthenol (vitamin B5) and not the L-Panthenol, so D,L-Panthenol has only half of the physiological activity of D-Panthenol.
D panthenol (vitamin B5) is a water-soluble cosmeceutical and readily penetrates the outermost layer of the epidermis (stratum corneum) to be metabolised into pantothenic acid (or Vitamin B5).
D panthenol (vitamin B5) occurs naturally in all living cells (pantothenic derives from ‘pantos’, meaning everywhere in Greek), and is often used in cosmetics as a humectant, or moisturiser because it attracts and infuses water into the skin cells.
When D panthenol (vitamin B5) is applied to the skin, it is converted into d-pantothenic acid, which easily penetrates the epidermis and produces the hydrating and healing effects.
However, D panthenol (vitamin B5) must be absorbed past the stratum corneum to work.
Once it’s been metabolised into pantothenic acid and moves deeper into the skin, D panthenol (vitamin B5) absorbs moisture, which in turn ‘plumps’ up the skin cells and smoothes them out, aiding in the reduction of fine lines and wrinkles.
D panthenol (vitamin B5) has a highly stable compound makeup and very low toxicity, so it’s safe to use and rarely has adverse effects.
D panthenol (vitamin B5) is included in many topical treatments for scarring, redness, itchiness and dryness of the skin.
Clinical research has shown that regular application over a period of four weeks or more has an anti-inflammatory effect.
D panthenol (vitamin B5) heals surface skin damage by stimulating dermal fibroblast production in the dermis, which is responsible for the repair and growth of connective tissue.
Although there isn’t much research for D panthenol (vitamin B5)5’s anti-ageing qualities, the hydrating powers work to rejuvenating mature skin.
D panthenol (vitamin B5) is the alcohol form of pantothenic acid (Vitamin B5).
D panthenol (vitamin B5) is a highly hygroscopic, viscous liquid ranging from colorless to slightly yellowish.
Following topical application, D panthenol (vitamin B5) is rapidly absorbed and converted into pantothenic acid, a key component of coenzyme A.
This conversion transforms dexD panthenol (vitamin B5) into a provitamin that supports skin regeneration, wound healing, and moisture retention.
D panthenol (vitamin B5) is the alcohol form of pantothenic acid.
D panthenol (vitamin B5) contains a primary amide group and multiple hydroxyl groups, which contributes to its high water solubility and hygroscopic properties.
D panthenol (vitamin B5) is optically active, and the D-(-)-form is the biologically active isomer.
After absorption, D panthenol (vitamin B5) is converted to pantothenic acid, which is essential for coenzyme A synthesis and cellular metabolism.
D panthenol (vitamin B5) is a clear, viscous, colorless to slightly yellowish liquid with a mild, characteristic odor.
D panthenol (vitamin B5) is supplied as a high-purity, high-viscosity liquid and is readily soluble in water and alcohol.
Due to its hygroscopic nature, D panthenol (vitamin B5) absorbs moisture from the air and should be stored in tightly closed containers.
D panthenol (vitamin B5) is a high-viscosity liquid with a density of approximately 1.19 g/cm³.
D panthenol (vitamin B5)'s high viscosity requires heating for easier handling in many applications.
D panthenol (vitamin B5) is hygroscopic (absorbs moisture), therefore it should be stored in tightly closed containers.
The pH of D panthenol (vitamin B5)'s aqueous solution is neutral to slightly acidic (5.0–7.0).
USES and APPLICATIONS of D PANTHENOL (VITAMIN B5):
D panthenol (vitamin B5) is widely used to repair damaged hair and promote healing.
Recommended Concentrations of D panthenol (vitamin B5): For optimal cosmetic formulations, usage rates typically range between 0.5% and 5% for skincare and 0.1% and 2% for hair products.
D panthenol (vitamin B5) is used in pharmaceutical and children's products as a moisturizer and to hasten wound healing.
In pharmaceutical applications, D panthenol (vitamin B5) is valued for its wound-healing and anti-inflammatory properties.
D panthenol (vitamin B5) is used in ointments for minor wounds, burns, and skin irritations.
Its ability to promote epithelialization makes D panthenol (vitamin B5) effective in treating skin disorders and in post-operative healing.
Moistening: D panthenol (vitamin B5) attracts and retains moisture to the skin.
Skin Barrier: D panthenol (vitamin B5) strengthens the skin barrier function.
Soothes irritation: D panthenol (vitamin B5) reduces inflammation and redness.
Wound Healing: D panthenol (vitamin B5) accelerates wound healing and tissue regeneration.
Anti-aging: D panthenol (vitamin B5) promotes cell regeneration and reduces fine lines.
In cosmetics, D panthenol (vitamin B5) is valued as a multifunctional ingredient.
D panthenol (vitamin B5) is a powerful humectant that attracts and retains moisture in the skin.
D panthenol (vitamin B5) strengthens the skin barrier, soothes irritation, and promotes wound healing.
D panthenol (vitamin B5) is particularly effective for sensitive skin, after-sun care, and anti-aging formulations.
Shampoos: D panthenol (vitamin B5) is used Moisturizing, scalp soothing.
Hair Conditioners: D panthenol (vitamin B5) strengthens and moisturizes the hair.
Hair Masks: D panthenol (vitamin B5) is used Deep conditioning, restorative.
Products Left Over Without Rinsing Moisturizing, strengthening.
Hair Serums Brightening and moisturizing.
Scalp Treatments: D panthenol (vitamin B5) is used Soothing, anti-inflammatory.
Anti-dandruff: D panthenol (vitamin B5) soothes the scalp and reduces flaking.
Hair Growth Products: D panthenol (vitamin B5) supports scalp health and hair growth.
In hair care, D panthenol (vitamin B5) is used for its moisturizing and strengthening properties.
D panthenol (vitamin B5) penetrates the hair shaft, providing deep hydration and improving hair elasticity.
D panthenol (vitamin B5) helps prevent split ends, reduces breakage, and gives hair a healthier, shinier appearance.
D panthenol (vitamin B5) also soothes the scalp and helps reduce flaking and irritation.
D panthenol (vitamin B5) is extensively used throughout the cosmetic and pharmaceutical industries due to its multifunctional biological activity.
In skincare products, D panthenol (vitamin B5) serves as a powerful humectant and skin-conditioning agent that improves hydration, reduces transepidermal water loss, and restores the natural skin barrier.
D panthenol (vitamin B5) is commonly incorporated into facial creams, body lotions, moisturizers, after-sun products, anti-aging formulations, baby care products, lip balms, facial masks, wound-healing creams, and products designed for sensitive or irritated skin.
Widely used in shampoos, conditioners, moisturizers, and medical products, D panthenol (vitamin B5) plays a significant role in preserving and revitalizing natural beauty.
D panthenol (vitamin B5) is used as a humectant and as a tissue-healing and conditioning agent in pharmaceutical and cosmetic products.
D panthenol (vitamin B5) is used as a moisturizer and humectant in cosmetics and personal care products.
D panthenol (vitamin B5) is found in lotions, ointments, nasal sprays, eye drops, cleaning solutions for contact lenses, etc.
Within hair care formulations, D panthenol (vitamin B5) functions as a conditioning agent that penetrates the hair cortex and helps improve elasticity, softness, shine, and resistance to mechanical damage.
D panthenol (vitamin B5) is widely used in shampoos, conditioners, leave-in treatments, hair masks, styling products, hair tonics, scalp serums, and anti-breakage formulations.
In the cosmetics and skincare industry, D panthenol (vitamin B5) is preferred more for its functional properties than its biological role.
Its moisture-retaining capacity and high compatibility with the skin, in particular, make D panthenol (vitamin B5) a valuable ingredient in formulations.
D panthenol (vitamin B5) gives good moisturizing and anti-inflammatory properties.
D panthenol (vitamin B5) is a good humectant for hair, and spreads evenly making hair easier to comb.
Use level of D panthenol (vitamin B5) is 0.3 - 5%.
D panthenol (vitamin B5) has a wide range of uses and is frequently found in the following products: Skin creams and lotions, Hair masks and shampoos, After-sun care products, Wound care creams, Body oils and lotions.
In pharmaceutical preparations, D panthenol (vitamin B5) is utilized in topical creams, ointments, gels, nasal sprays, eye drops, oral mucosal products, burn treatments, wound dressings, and dermatological medications intended to accelerate tissue regeneration and relieve irritation.
D panthenol (vitamin B5) is also found in veterinary preparations for skin care and wound management.
Due to its excellent moisturizing, soothing, and regenerative properties, D panthenol (vitamin B5) is widely used in cosmetics, personal care products, pharmaceuticals, dermatological formulations, oral care products, veterinary preparations, and certain food and nutritional applications.
Additional applications of D panthenol (vitamin B5) include oral care products such as toothpaste and mouthwash, cosmetic sprays, shaving products, hand sanitizers, cleansing formulations, and nutritional supplements where pantothenic acid activity is desired.
Recommended usage rates of D panthenol (vitamin B5): 1-5% in moisturizing creams and lotions, 0.5-2% in shampoos and conditioners, 1-5% in hair masks, 1-5% in face masks, 1-3% in hand and body lotions, 1-2% in lip balms, and 0.5-1% in eye contour products.
D panthenol (vitamin B5) is a multifunctional cosmetic ingredient valued for its humectant and conditioning properties in skin and hair care formulations.
D panthenol (vitamin B5) effectively penetrates the skin and the hair fiber, where it enhances moisture retention, supports barrier function, and improves overall softness and and elasticity.
In skincare applications, liquid D panthenol (vitamin B5) helps to soothe the skin and contributes to a smoother, more resillient appearance.
In hair care products, D panthenol (vitamin B5) provides conditioning benefits, improves shine and manageability, and helps to reduce hair damage.
Owing to D panthenol (vitamin B5)'s excellent solubility, formulation flexibility, and broad compatibility, liquid panthenol is well suited for use in a wide rage of cosmetic products.
Add D panthenol (vitamin B5) to cold or hot formulas, usual final concentration 0.5-5%.
D panthenol (vitamin B5) is used for external use only.
Applications of D panthenol (vitamin B5): Creams, lotions, shampoos, conditioners, body washes, makeup.
D panthenol (vitamin B5) acts as a moisturiser, penetrating the top layer of skin and nails, whilst stabilising and boosting skin metabolism.
D panthenol (vitamin B5) also acts as a soothing agent and helps prevent inflammation.
D panthenol (vitamin B5) can also penetrate the hair shaft's cortex, strengthening and protecting it whilst improving the hair's shine, feel and flexibility, making it easier to handle.
Due to its moisturizing, soothing, and healing properties, D panthenol (vitamin B5) is widely used in cosmetics, dermatology, and pharmaceutical products.
-Hair Care uses of D panthenol (vitamin B5):
D panthenol (vitamin B5) acts as a long-lasting moisturizer.
D panthenol (vitamin B5) thickens hair while preventing damage.
D panthenol (vitamin B5) enhances sheen and luster for a glossy, healthy look.
-Skin Care uses of D panthenol (vitamin B5):
Deeply penetrates for soft, hydrated skin.
Provides anti-inflammatory benefits, soothing and calming irritated skin.
Releases D panthenol (vitamin B5) amd transforms into pantothenic acid to act as an anti-inflammatory hydration additive to aid eczema, insect bites and nappy rash.
-Nail Care uses of D panthenol (vitamin B5):
D panthenol (vitamin B5) improves hydration and flexibility for stronger, healthier nails.
D panthenol (vitamin B5) stays in its pro-vitamin form
-D panthenol (vitamin B5) in cosmetic products:
D panthenol (vitamin B5) supports moisture retention capacity.
D panthenol (vitamin B5) provides a feeling of softness on the skin and hair surface.
D panthenol (vitamin B5) increases the convenience of using skincare products.
D panthenol (vitamin B5) contributes to the balance of the formulation.
In addition to all these benefits, D panthenol (vitamin B5) also helps maintain skin elasticity and strengthens hair.
Thanks to these properties, D panthenol (vitamin B5) has a wide range of uses, from daily care products to professional cosmetics.
-Pharmacology uses of D panthenol (vitamin B5):
D panthenol (vitamin B5) readily penetrates into the skin and mucous membranes (including the intestinal mucosa), where it is quickly oxidized to pantothenic acid.
D panthenol (vitamin B5) is extremely hygroscopic.
D panthenol (vitamin B5) is also used in the biosynthesis of coenzyme A, which plays a role in a wide range of enzymatic reactions and in cell growth.
-Applications of D panthenol (vitamin B5):
• Skincare: serums, moisturizers, gels, facial cleansers
• Haircare: shampoos, conditioners, leave-in treatments
• Body care: lotions, creams, hand creams, after-sun products
• Baby care and sensitive skin formulations
• Repair balms, soothing gels, and barrier creams
-D panthenol (vitamin B5) is used :
Wound Healing Ointments: The active ingredient supports tissue regeneration.
Burn Treatments: Soothing, anti-inflammatory, promotes healing.
Skin irritation: Soothes irritated skin and rashes.
Dermatological Preparations: Anti-inflammatory, skin barrier support.
-D panthenol (vitamin B5) is used :
Hemorrhoid Treatments: Soothing, anti-inflammatory.
Oral Ulcer Treatments: Soothing, healing, anti-inflammatory.
Topical Analgesics: Anti-inflammatory, soothing.
Creams and Ointments: Base ingredient, sedative agent.
Eye Drops: Moisturizing, soothing.
Nasal Sprays: Moisturizing, soothing.
Wicks: Soothing, healing.
-Areas of Use and Recommended Rates:
Face and body creams: 0.5% – 5%
Hair care products (shampoo, conditioner, mask): 0.1% – 2%
Baby products: 0.5% – 2%
After-sun care products: 1-5%
-D panthenol (vitamin B5)'s contributions to hair care:
D panthenol (vitamin B5) helps hair strands appear more flexible.
D panthenol (vitamin B5) provides a feeling of softness to dry and damaged hair.
Hair care products contribute to easier detangling.
D panthenol (vitamin B5) supports the moisture balance of the scalp.
These benefits make D panthenol (vitamin B5) a commonly used ingredient in both skin and hair care products.
-Wound Healing uses of D panthenol (vitamin B5):
Topical dexpanthenol use has been scientifically reported to support wound healing and contribute to epidermal barrier repair.
D panthenol (vitamin B5) plays a significant role in the wound healing process and helps maintain skin health.
Pantothenic acid strengthens the skin barrier, increasing the skin's self-renewal capacity.
This can reduce the formation of scars and allow the skin to recover faster.
Additionally, D panthenol (vitamin B5) helps reduce inflammation in the skin and supports the healing process.
During wound healing, skincare products or supplements containing D panthenol (vitamin B5) can contribute to strengthening the skin barrier and promoting a healthy appearance of the skin.
However, it is important to consult a healthcare professional before using any supplements or products.
WHAT IS D PANTHENOL (VITAMIN B5) USED FOR?
D panthenol (vitamin B5) is a versatile active ingredient.
Therefore, D panthenol (vitamin B5) has a very wide range of uses in cosmetic production.
For example:
D panthenol (vitamin B5) intensely moisturizes the skin and reduces water loss.
D panthenol (vitamin B5) strengthens the skin barrier and supports repair.
D panthenol (vitamin B5) adds shine and softness to the hair.
D panthenol (vitamin B5) strengthens hair strands and reduces breakage.
D panthenol (vitamin B5) has a soothing effect on the skin.
Therefore, D panthenol (vitamin B5) is a powerful component that provides both maintenance and protection.
PROPERTIES AND USES OF D PANTHENOL (VITAMIN B5):
D panthenol (vitamin B5) has moisturizing and water-retaining properties.
D panthenol (vitamin B5) increases skin and hair moisture, providing softness.
D panthenol (vitamin B5) is stable against light and heat and sensitive to oxidation.
D panthenol (vitamin B5) strengthens the skin's natural barrier functions and helps repair irritated skin areas.
D panthenol (vitamin B5) is found in various products such as moisturizers, serums, lotions, and face masks.
D panthenol (vitamin B5) is used in products such as shampoos, conditioners, hair masks, and hair serums to support hair health.
In after-sun products, D panthenol (vitamin B5) soothes and moisturizes the skin.
D panthenol (vitamin B5) is included in products such as foundations and BB creams to provide skin care.
D panthenol (vitamin B5) is used in aftershave balms and creams to soothe the skin and reduce irritation.
D panthenol (vitamin B5) is generally suitable for sensitive skin and has a low risk of allergic reactions.
FOODS THAT USUALLY CONTAIN D PANTHENOL (VITAMIN B5) INCLUDE:
Meats like beef, poultry, and seafood
Milk and eggs
Vegetables like avocados, broccoli, mushrooms, and potatoes
Whole grains like whole-wheat bread and brown rice
Peanuts, sunflower seeds, and chickpeas
WHY IS D PANTHENOL (VITAMIN B5) PREFERRED IN COSMETICS?
Cosmetic manufacturers prefer depanthenol, especially because of its versatile effect.
This is because a single ingredient provides multiple benefits.
With this:
Suitable for sensitive skin.
D panthenol (vitamin B5) provides a stable structure in formulas.
D panthenol (vitamin B5) easily mixes with other active ingredients.
Improves product performance.
Therefore, D panthenol (vitamin B5) is frequently used by both professional brands and boutique manufacturers.
6 ESSENTIAL EVIDENCE-BASED BENEFITS OF D PANTHENOL (VITAMIN B5) FOR SKIN:
D panthenol (vitamin B5)'s popularity in skincare is based on a wide range of benefits that are not limited to a single function.
Research shows that D panthenol (vitamin B5) supports skin health in a multifaceted way.
Another point to consider regarding D panthenol (vitamin B5) in skincare is this:
***Powerful Hydration and Barrier Repair:
D panthenol (vitamin B5)'s best-known property is its ability to increase the skin's moisture retention capacity.
A clinical study revealed that a preparation containing D panthenol (vitamin B5) significantly increased skin hydration and strengthened skin barrier function (Proksch et al., 2008).
By promoting lipid synthesis, D panthenol (vitamin B5) strengthens the skin's natural protective layer and makes it more resistant to environmental stressors.
***Soothing Irritation and Reducing Redness:
D panthenol (vitamin B5) exhibits significant anti-inflammatory properties, making it an ideal ingredient for sensitive, reddened, sunburned, or irritated skin after shaving or ingrown hairs.
By modulating the inflammatory response in the skin, D panthenol (vitamin B5) helps reduce discomfort and visible redness.
***Increasing Skin Elasticity and Softness:
As moisture levels increase, the skin takes on a fuller, smoother, and softer appearance.
D panthenol (vitamin B5) supports skin elasticity, increasing the feeling of firmness and providing a noticeable softness to the touch.
Research reveals significant results regarding D panthenol (vitamin B5) in skincare.
***Supporting Wound and Microscopic Crack Healing:
D panthenol (vitamin B5) is notable for its role in accelerating skin repair processes.
By promoting cell proliferation and epithelialization, D panthenol (vitamin B5) can shorten the healing time of minor cuts, scrapes, cracks, or peels.
***Supportive Role in Acne-Prone Skin:
Oily or acne-prone skin often undergoes drying treatments.
D panthenol (vitamin B5), with its non-comedogenic (non-pore-clogging) formula, is an excellent option for restoring moisture balance in these skin types.
By preventing excessive dryness and associated irritation, D panthenol (vitamin B5) mitigates the side effects of active ingredients like salicylic acid or benzoyl peroxide and maintains the skin barrier throughout the treatment period.
***Anti-Aging Support:
Moisture is key to healthy, youthful-looking skin.
D panthenol (vitamin B5) replenishes the skin's moisture reserves, temporarily softening the appearance of fine lines and wrinkles.
Furthermore, a healthy skin barrier provides better defense against environmental aging factors.
These factors should be considered when evaluating D panthenol (vitamin B5) skincare products.
WHERE IS D PANTHENOL (VITAMIN B5) FOUND?
You can find D panthenol (vitamin B5) in many common self-care and cosmetic products.
Hair products.
If you are looking for a moisturizing and nourishing hair product, you’ll find many shampoos and conditioners with D panthenol (vitamin B5).
D panthenol (vitamin B5) is also in many styling gels, hair mousses, hair sprays, and detanglers.
Skincare products.
You can find many products with D panthenol (vitamin B5) for your self-care and skin care routine.
These include facial moisturizers, face masks, serums, facial cleansers, toners, eye creams, sunscreens, makeup removers, bubble baths, and shaving cream products.
Cosmetic products.
When it comes to your makeup, you’ll find D panthenol (vitamin B5) in items you use every day.
This includes some mascaras, foundations, brow liners, eyeliners, lipsticks, bronzers, highlighters, and setting powders or sprays.
Baby products.
Because D panthenol (vitamin B5) is safe for skin, you can even find some baby products with it.
These include baby shampoo, lotion, soap, and sunscreen.
Be sure to monitor your baby’s skin to determine if certain products give them skin rashes or not.
D panthenol (vitamin B5) is the alcohol analog of pantothenic acid (vitamin B5).
KEY BENEFITS OF D PANTHENOL (VITAMIN B5):
Deeply hydrates and helps retain moisture
Soothes dry, irritated, or sensitive skin
D panthenol (vitamin B5) improves skin smoothness and elasticity
D panthenol (vitamin B5) supports the skin's natural protective barrier
D panthenol (vitamin B5) enhances hair softness, shine, and manageability
HOW TO USE D PANTHENOL (VITAMIN B5):
Add to the water phase of formulations or incorporate during the cool-down phase.
D panthenol (vitamin B5) is generally recommended to add the liquid panthenol once your formulation has cooled to below 40°C to ensure maximum potency and stability.
Typical Usage Rate of D panthenol (vitamin B5): 0.5% - 5%
BENEFITS OF D PANTHENOL (VITAMIN B5) FOR SKIN:
Humectant and Moisturizer / Moisturizing, Retaining moisture
D panthenol (vitamin B5) acts as a humectant or a good moisture retaining substance.
D panthenol (vitamin B5) helps form a skin barrier, preventing moisture loss.
D panthenol (vitamin B5) is ideal for dry skin as it helps to moisturize, protects against moisture loss, keeps the skin soft and increases skin elasticity.
WHAT IS D PANTHENOL (VITAMIN B5) USED FOR, WHAT ARE ITS BENEFITS, AND WHAT IS D-PANTHENOL?
Questions such as "What is D panthenol (vitamin B5)?", "What is D panthenol (vitamin B5) used for?", "What are its benefits?", and "What is D panthenol (vitamin B5)?" are frequently researched, especially by those interested in skin and hair care ingredients.
D panthenol (vitamin B5), or pantothenic acid, has significant effects on energy production, metabolism, skin health, hair care, and the immune system.
In cosmetics and personal care products, D panthenol (vitamin B5) stands out for its moisturizing properties, barrier strengthening, and formulation compatibility.
The most commonly used form in cosmetic production is known as D panthenol (vitamin B5).
Additionally, D panthenol (vitamin B5) is found in many different sources such as fruits, vegetables, meat, poultry, and grains.
RECOMMENDED PH RANGE OF D PANTHENOL (VITAMIN B5):
The recommended range is pH 4.0-7.0.
Within this pH range, D-D panthenol (vitamin B5) remains stable in formulations and exhibits maximum effectiveness.
This pH range is generally preferred in skin and hair care products because D panthenol (vitamin B5) is both skin-compatible and preserves the properties of the ingredient.
SOLUBILITY OF D PANTHENOL (VITAMIN B5):
D panthenol (vitamin B5) is completely miscible with water.
D panthenol (vitamin B5) is also miscible with alcohol and glycerol.
KEY BENEFITS OF D PANTHENOL (VITAMIN B5) IN SKINCARE:
D panthenol (vitamin B5) helps maintain the moisture balance on the skin's surface.
D panthenol (vitamin B5) helps reduce the feeling of tightness caused by dryness.
D panthenol (vitamin B5) helps the skin barrier appear more balanced.
D panthenol (vitamin B5) can be used in formulations suitable for sensitive skin types.
BENEFITS OF D PANTHENOL (VITAMIN B5):
D panthenol (vitamin B5) provides exceptional moisturizing performance by attracting and retaining water within the skin, resulting in improved hydration, softness, and elasticity.
D panthenol (vitamin B5) strengthens the skin barrier, helping reduce moisture loss while protecting against environmental stressors.
D panthenol (vitamin B5)'s soothing and anti-inflammatory effects help calm redness, itching, irritation, and discomfort associated with dry or compromised skin.
Another major advantage is D panthenol (vitamin B5)'s ability to stimulate epidermal regeneration and support wound healing by promoting cellular proliferation and tissue repair.
These properties make D panthenol (vitamin B5) highly valuable in products intended for damaged skin, minor burns, post-procedure care, and dermatological treatments.
For hair care, D panthenol (vitamin B5) significantly improves hair texture by increasing moisture retention, reducing brittleness, enhancing flexibility, and providing a smoother, shinier appearance.
D panthenol (vitamin B5) also helps reduce split ends and improves manageability without weighing down the hair.
Its excellent compatibility with numerous cosmetic ingredients, broad pH tolerance, low irritation potential, high safety profile, and ease of formulation have made D panthenol (vitamin B5) one of the most widely used active ingredients in modern personal care products.
FUNCTION OF D PANTHENOL (VITAMIN B5):
• D panthenol (vitamin B5) acts as an effective humectant to attract and retain moisture
• D panthenol (vitamin B5) strengthens the skin barrier and improves elasticity
• D panthenol (vitamin B5) reduces redness, irritation, and inflammation
• D panthenol (vitamin B5) enhances hair shine, softness, and reduces breakage
• D panthenol (vitamin B5) promotes wound healing and skin regeneration
• D panthenol (vitamin B5) improves product spreadability and texture
USES AND BENEFITS OF D PANTHENOL (VITAMIN B5) IN SKIN CARE:
While new trends and active ingredients constantly emerge in the skincare world, some stand the test of time and become indispensable.
D panthenol (vitamin B5) is one such active ingredient, possessing a solid scientific background and versatility.
Its superior ability to repair the skin barrier and provide deep hydration makes D panthenol (vitamin B5) a safe haven for a wide range of users, from sensitive skin to acne-prone skin.
WHAT ARE THE BENEFITS OF D PANTHENOL (VITAMIN B5)?
Clinical studies on D panthenol (vitamin B5) have shown that this compound supports skin barrier function and increases moisture levels.
The question of what the benefits of D panthenol (vitamin B5) are is particularly important for users focusing on skin and hair care.
These benefits are evaluated not in terms of direct treatment, but in terms of supportive and protective properties.
D panthenol (vitamin B5) helps maintain the skin's moisture balance.
D panthenol (vitamin B5) helps to increase skin elasticity.
D panthenol (vitamin B5) strengthens the skin barrier.
D panthenol (vitamin B5) helps hair look shinier and healthier.
D panthenol (vitamin B5) can be used in formulations suitable for sensitive skin and may have a soothing effect.
HOW TO USE D PANTHENOL (VITAMIN B5)?
Before using products containing D panthenol (vitamin B5), it is recommended to apply them to clean skin or hair.
For skin care, D panthenol (vitamin B5) can be used several times a day; for hair care, it can be used as needed.
For best results, please use the recommended amount.
KEY FEATURES OF D PANTHENOL (VITAMIN B5):
Moisturizing and moisture-retaining.
Reducing irritation and soothing.
Supports cell regeneration.
Increases skin elasticity.
Hair strengthener
FUNCTION OF D PANTHENOL (VITAMIN B5):
Moisturizing,
emollient,
skin barrier supporting.
WHAT IS D PANTHENOL (VITAMIN B5) USED FOR?
D panthenol (vitamin B5) is used as a moisturizer, soothing and softening agent.
Skin care:
D panthenol (vitamin B5) improves hydration and elasticity of the skin, reduces itching and inflammation of the skin, improves skin elasticity, and accelerates the rate of healing of wounds.
In topical creams, D panthenol (vitamin B5) is found to be in a concentration of 1-5%.
Hair care:
D panthenol (vitamin B5) binds to the hair shaft readily, so, it is a common component of commercial shampoos and hair conditioners (in concentrations of 0.1-1%).
D panthenol (vitamin B5) coats the hair and seals its surface, lubricating the hair shaft and giving it a shiny appearance.
D panthenol (vitamin B5) can also help protect your hair from styling or environmental damage by locking in moisture.
ORIGIN OF D PANTHENOL (VITAMIN B5):
D panthenol (vitamin B5) is produced synthetically by condensing D-pantolactone with 3-aminopropanol, yielding D panthenol (vitamin B5) (biologically active form).
Cosmetic-grade D panthenol (vitamin B5) is highly purified (>98%) and typically supplied as a viscous liquid (75-100% active) or powder (DL-D panthenol (vitamin B5), racemic mixture).
It is identical to the form naturally present in the body and widely accepted in natural, organic, and sensitive-skin formulations.
WHAT DOES D PANTHENOL (VITAMIN B5) DO IN A FORMULATION?
HAIR CONDITIONING
HUMECTANT
SKIN CONDITIONING
SOOTHING
SAFETY PROFILE OF D PANTHENOL (VITAMIN B5):
D panthenol (vitamin B5) is generally well tolerated.
In rare cases, skin irritation and contact allergies have been reported.
Both the U.S. Food and Drug Administration (FDA) and the European Commission on Cosmetic Ingredients have approved D panthenol (vitamin B5) for use in cosmetics.
The National Institutes of Health (NIH) classifies D panthenol (vitamin B5) as "possibly safe" for general topical applications and nasal sprays.
ALTERNATIVES OF D PANTHENOL (VITAMIN B5):
*ACETYL GLUCOSAMINE
*ALLANTOIN
*UREA
BENEFITS OF D PANTHENOL (VITAMIN B5):
D panthenol (vitamin B5) penetrates readily into skin & hair.
D panthenol (vitamin B5) has good moisturizing and softening properties.
D panthenol (vitamin B5) soothes irritated and blemished skin.
D panthenol (vitamin B5) gives the hair moisture & shine and reduces split ends.
CHARACTERISTICS OF D PANTHENOL (VITAMIN B5):
D panthenol (vitamin B5) is one of the most versatile multifunctional ingredients used in cosmetic, pharmaceutical, and personal care formulations.
Once absorbed into the skin, D panthenol (vitamin B5) is rapidly oxidized into pantothenic acid, where it participates in numerous biochemical pathways involved in cellular metabolism and tissue repair.
Its outstanding humectant properties allow D panthenol (vitamin B5) to attract and retain water within the stratum corneum, helping to maintain skin hydration and elasticity.
In addition to its moisturizing activity, D panthenol (vitamin B5) exhibits soothing, anti-inflammatory, and barrier-repair properties, making it particularly useful for sensitive, irritated, or damaged skin.
D panthenol (vitamin B5) enhances epidermal regeneration, supports wound healing, and improves the overall condition of the skin without causing irritation.
For hair care applications, D panthenol (vitamin B5) penetrates the hair shaft, improves moisture retention, reduces brittleness, increases flexibility, enhances shine, and contributes to thicker-looking hair by coating and temporarily swelling the hair fiber.
D panthenol (vitamin B5) also improves combability and reduces split ends.
Because of its excellent compatibility with emulsions, gels, creams, lotions, shampoos, conditioners, serums, sprays, ointments, and pharmaceutical dosage forms, D panthenol (vitamin B5) is incorporated into thousands of commercial formulations worldwide.
STRUCTURE AND MECHANISM OF ACTION OF D PANTHENOL (VITAMIN B5):
D panthenol (vitamin B5) converts to pantothenic acid when applied to the skin.
This helps regenerate skin cells.
D panthenol (vitamin B5) also retains moisture in the skin, providing long-lasting hydration.
D panthenol (vitamin B5) thickens hair strands and gives them a fuller appearance, especially by forming a protective film on the hair.
Therefore, D panthenol (vitamin B5) is frequently used in shampoos and hair serums.
WHAT IS D PANTHENOL (VITAMIN B5) USED FOR?
D panthenol (vitamin B5) moisturizes and renews the skin while also nourishing the hair.
In hair care products, D panthenol (vitamin B5) nourishes hair strands, prevents breakage, and gives a healthy appearance.
In skin care products, D panthenol (vitamin B5) locks in moisture, provides softness, reduces sensitivity, and revitalizes the skin.
Therefore, D panthenol (vitamin B5) is an indispensable component of daily skin and hair care routines.
FEATURES AND BENEFITS OF D PANTHENOL (VITAMIN B5):
Moisturizing Effect:
D panthenol (vitamin B5) provides deep hydration to the skin.
By reducing water loss from the skin, D panthenol (vitamin B5) prevents dryness.
Skin Repair:
D panthenol (vitamin B5) promotes skin cell renewal.
D panthenol (vitamin B5) helps heal wounds, cuts, and other skin damage.
Anti-inflammatory Properties:
Thanks to its skin-soothing effect, D panthenol (vitamin B5) reduces redness and irritation.
D panthenol (vitamin B5) is ideal for sensitive skin.
Hair Health:
When used in hair care products, D panthenol (vitamin B5) nourishes and strengthens the hair strand.
D panthenol (vitamin B5) contributes to a brighter, healthier, and more vibrant appearance of the hair.
Collagen Production Stimulator:
D panthenol (vitamin B5) increases collagen synthesis in the skin, providing protection against signs of aging.
Ease of Application:
D panthenol (vitamin B5) can be easily applied in both liquid and gel forms.
D panthenol (vitamin B5) is widely used in skin and hair care products for its intense moisturizing properties.
BENEFITS OF D PANTHENOL (VITAMIN B5):
D panthenol (vitamin B5) is 100% plant-based and vegan.
D panthenol (vitamin B5) helps prevent underarm darkening and inhibits the formation of new stains.
D panthenol (vitamin B5) balances the underarm microbiome with postbiotics.
D panthenol (vitamin B5) nourishes and repairs the underarm area with oils.
Free of aluminum and carbonates.
D panthenol (vitamin B5)uitable for use on sensitive skin.
D panthenol (vitamin B5) protects against body odor all day long.
WHERE IS D PANTHENOL (VITAMIN B5) FOUND?
A D panthenol (vitamin B5) might help with your metabolism or cholesterol levels.
FUNCTION OF D PANTHENOL (VITAMIN B5):
D panthenol (vitamin B5) 75W acts as an effective moisturizing and repairing ingredient while providing stability in cosmetic and pharmaceutical formulations.
D panthenol (vitamin B5) promotes cell regeneration, helping to heal minor wounds and irritations on the skin.
D panthenol (vitamin B5) increases skin elasticity, making the skin smoother and softer.
D panthenol (vitamin B5) strengthens hair strands, prevents breakage, and adds shine.
PHYSICAL STRUCTURE OF D PANTHENOL (VITAMIN B5):
Provitamin B5, chemically known as D panthenol (vitamin B5), is a water-based vitamin.
D panthenol (vitamin B5) is a viscous liquid with a mild, characteristic odor.
D panthenol (vitamin B5) is generally close to the boiling point of water.
WHAT IS D PANTHENOL (VITAMIN B5) AND HOW DOES IT WORK IN SKIN CARE?
D panthenol (vitamin B5) is the stable, alcoholic form of pantothenic acid (vitamin B5), an essential B vitamin.
In the context of skincare, D panthenol (vitamin B5)'s also referred to as "provitamin B5" because upon contact with the skin, it enzymatically converts to pantothenic acid and begins its active function.
This conversion is a critical feature that makes D panthenol (vitamin B5) more stable and effective in skincare formulas.
D panthenol (vitamin B5)'s primary mechanism of action on the skin stems from its strong humectant (moisture-retaining) properties.
By forming a light, moisture-trapping film layer on the skin's surface, it significantly reduces transepidermal water loss (TEWL).
However, D panthenol (vitamin B5)'s true value extends beyond this superficial hydration.
When converted to pantothenic acid within skin cells, D panthenol (vitamin B5) forms the building blocks of coenzyme A (CoA), vital for all living cells in the body.
Coenzyme A plays a central role in the synthesis of lipids responsible for the structural integrity of the skin barrier, including fatty acids, cholesterol, and sphingolipids.
Therefore, D panthenol (vitamin B5) supports the skin's self-repair and protective capacity, contributing to the rebuilding of a healthy barrier that keeps moisture out.
BENEFITS OF D PANTHENOL (VITAMIN B5):
Moisturizing:
D panthenol (vitamin B5) maintains the moisture balance of skin and hair.
Renewal:
D panthenol (vitamin B5) repairs irritated skin and damaged hair strands.
Shine and Elasticity:
D panthenol (vitamin B5) gives hair a natural shine and elasticity.
Soothing:
D panthenol (vitamin B5) reduces redness and irritation of the skin.
Strengthening:
D panthenol (vitamin B5) strengthens hair follicles, preventing breakage.
WHAT IS D PANTHENOL (VITAMIN B5) AND HOW DOES IT WORK?
D panthenol (vitamin B5), also known as Dexpanthanol or Pro-Vitamin B5, is the precursor to Vitamin B5.
The Mechanism:
Once applied, D panthenol (vitamin B5) is rapidly absorbed by the skin or hair and converted into Pantothenic Acid (Vitamin B5).
The Role:
D panthenol (vitamin B5) is a vital component of Coenzyme A, which acts as the "engine" for cellular energy metabolism and skin barrier repair.
WHAT ARE THE KEY BENEFITS OF D PANTHENOL (VITAMIN B5) FOR SKIN?
According to dermatological research, D panthenol (vitamin B5) offers far more than just surface hydration:
Moisturizing and Skin Barrier Repair:
D panthenol (vitamin B5) enhances the skin's ability to retain moisture, replenishes the stratum corneum's moisture reserves, and increases skin hydration.
D panthenol (vitamin B5) improves skin barrier function and reduces transepidermal water loss (TEWL).
Soothing and Anti-inflammatory:
D panthenol (vitamin B5) inhibits the release of inflammatory factors, thereby reducing inflammation and soothing the skin.
Wound Healing:
D panthenol (vitamin B5) promotes cell migration and proliferation, significantly shortening the wound repair cycle.
IS D PANTHENOL (VITAMIN B5) EFFECTIVE FOR HAIR CARE?
Absolutely.
D panthenol (vitamin B5) is a staple in high-end hair care formulations for several reasons:
Long-lasting Hydration:
Unlike surfactants that wash away, D panthenol (vitamin B5) penetrates the hair shaft to prevent dryness.
Enhanced Elasticity:
By improving the hair structure, D panthenol (vitamin B5) reduces breakage caused by mechanical combing and styling.
Radiant Shine:
D panthenol (vitamin B5) forms a smooth, thin film on the hair surface, enhancing natural light reflection and luster.
PHYSICAL AND CHEMICAL PROPERTIES OF D PANTHENOL (VITAMIN B5):
D panthenol (vitamin B5) is an odourless, slightly bitter, highly viscous, transparent, and colourless liquid at room temperature, but salts of pantothenic acid (for example sodium pantothenate) are powders that are typically white.
D panthenol (vitamin B5) is easily soluble in water and alcohol, moderately soluble in diethyl ether, soluble in chloroform (1:100), in propylene glycol, and slightly soluble in glycerin.
D panthenol (vitamin B5)'s expanded chemical formula is HO–CH2–C(CH3)2–CH(OH)–CONH–CH2CH2CH2–OH.
Stereochemistry
D panthenol (vitamin B5) comes in two enantiomers: D, and L.
Only D panthenol (vitamin B5) (dexpanthenol) is biologically active, however both forms have moisturizing properties.
For cosmetic use, D panthenol (vitamin B5) comes either in D form, or as a racemic mixture of D and L (DL-D panthenol (vitamin B5)).
KEY BENEFITS OF D PANTHENOL (VITAMIN B5):
A more stable version of pantothenic acid (Vitamin B5).
rotects and seals in moisture for skin and hair.
Dual function to enhance skin and hair.
Skin barrier function to protect and seal in moisture.
Humectant for hair to improve scalp & promote soft shiny hair.
Anti-inflammatory for sensitive skin.
Humectant for skin.
D panthenol (vitamin B5) aids in ease of combability to prevent hair breakage.
Improved elasticity of hair strands to prevent breakage.
Skin soothing for sensitive skin.
Adheres to the hair cuticle and penetrates to the cortex.
Adds shine to hair.
KEY BENEFITS OF D PANTHENOL (VITAMIN B5):
Skin Hydration:
D panthenol (vitamin B5) attracts and retains moisture, effectively reducing water loss to keep skin supple and soft.
Soothing & Healing:
D panthenol (vitamin B5) possesses anti-inflammatory properties that help calm irritated skin, reduce redness, and accelerate wound healing.
Hair Strengthening:
D panthenol (vitamin B5) binds to hair shafts, adding natural shine, reducing split ends, and improving overall strength and combability.
SOURCES OF D PANTHENOL (VITAMIN B5)
D panthenol (vitamin B5), or pantothenic acid, occurs naturally in many animal and plant-based foods.
A balanced diet can usually easily meet the body's D panthenol (vitamin B5) needs.
Meat, chicken, eggs, whole grains, avocados, broccoli, and some nuts are rich sources of pantothenic acid.
Dairy products and legumes also contain D panthenol (vitamin B5).
This vitamin plays an important role in the body's energy production and nervous system health.
Including these food groups in your daily diet helps reduce the risk of D panthenol (vitamin B5) deficiency.
D panthenol (vitamin B5) supplements can also be used if needed.
WHAT ARE THE BENEFITS OF D PANTHENOL (VITAMIN B5)?
The question of what D panthenol (vitamin B5) is used for becomes clearer when considered from a cosmetic and personal care perspective.
D panthenol (vitamin B5) is positioned as a supporting ingredient in skin and hair care products.
D panthenol (vitamin B5)'s primary purpose is to support the moisture balance of the skin and hair and to enhance the performance of care products.
Additionally, D panthenol (vitamin B5) contributes to the moisturizing and repair processes in skin and hair care products.
PHYSICAL and CHEMICAL PROPERTIES of D PANTHENOL (VITAMIN B5):
INCI Name: Panthenol
CAS Number: 81-13-0
Chemical Formula: C₉H₁₉NO₄
Form: Liquid or powder form
Appearance: Colorless to light yellow
Odor: Mild characteristic, usually odorless.
Solubility: Soluble in water.
pH Compatibility: Stable over a wide pH range.
Product Name: D-Panthenol Liquid (B5 Provitamin)
Chemical Formula: C9H19NO4
CAS No: 81-13-0
EINESC No: 201-327-3
UN No: Not classified as a hazardous product
Physical Properties: Colorless Liquid
Odor: Characteristic odor
Molecular Weight: 205.3 g/mol
Density: 1.20 g/cm3
Solubility: Soluble in water
Chemical formula: C9H19NO4
Molar mass: 205.254 g·mol−1
Appearance: Highly viscous, colourless liquid
Density: 1.2 g mL−1 (at 20 °C)
Melting point: 66 to 69 °C (151 to 156 °F; 339 to 342 K) [contradictory]
Boiling point: 118 to 120 °C (244 to 248 °F; 391 to 393 K) at 2.7 Pa
log P: −0.989
Acidity (pKa): 13.033
Basicity (pKb): 0.964
Chiral rotation ([α]D): +29° to +30°
Refractive index (nD): 1.499
CAS: 81-13-0
Product Name: Dexpanthenol
CAS Number: 81-13-0
EC Number: 201-327-3
Chemical Class: Vitamin B5 Derivative (Alcohol)
Chemical Family: Vitamin B Complex (Provitamin B5)
Structure: Alcohol derivative of pantothenic acid
Functional Groups: Hydroxyl (-OH), Amide (-CONH)
Stereochemistry: D-(-)-form (optically active)
SMILES: CC(C)(CO)C(O)C(=O)NCCCO
InChi Key: SNPLKNRPJHDVJA-UHFFFAOYSA-N
Optical Rotation: +29° to +31.5°
Chemical Name: D-Panthenol
Common Name: Vitamin B5 Alcohol, Provitamin B5
IUPAC Name: (R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
CAS Number: 81-13-0
EC Number: 201-327-3
Molecular Formula: C9H19NO4
Molecular Weight: 205.25 g/mol
Chemical Family: Pantothenic Acid Derivative
Substance Type: Vitamin Derivative
Physical State: Solid or highly viscous liquid (depending on grade)
Appearance: Colorless to pale yellow viscous liquid or white crystalline powder (depending on grade)
Physical State: Liquid or crystalline solid
Color: Colorless, nearly colorless, or white
Odor: Odorless or faint characteristic odor
Taste: Slightly bitter
Molecular Formula: C9H19NO4
Molecular Weight: 205.25 g/mol
Density (20°C): Approximately 1.20 g/cm³ (liquid grade)
Melting Point: Approximately 64–68°C (solid form)
Boiling Point: Decomposes before boiling
Flash Point: Above 100°C
Water Solubility: Completely miscible with water
Solubility in Ethanol: Freely soluble
Solubility in Methanol: Soluble
Solubility in Propylene Glycol: Soluble
Solubility in Glycerin: Soluble
Solubility in Oils: Practically insoluble
pH (10% aqueous solution): Approximately 8.5–10.5
Refractive Index (20°C): Approximately 1.495–1.505 (liquid grade)
Viscosity: High (liquid grade)
Hygroscopicity: Highly hygroscopic
Optical Rotation: Positive (D-isomer)
Stability: Stable under normal storage conditions
Heat Stability: Good under recommended formulation temperatures
Oxidation Resistance: Good
Hydrolysis: Stable under neutral conditions
Compatibility: Compatible with most cosmetic ingredients
UV Stability: Good
Volatility: Very low
Vapor Pressure: Negligible
Surface Activity: Non-surfactant
Biodegradability: Readily biodegradable
Bioavailability: Excellent after topical absorption
Skin Penetration: High
Film-Forming Ability: Moderate
Moisture Retention Capacity: Excellent
Humectant Properties: Excellent
Shelf Stability: Good under dry, cool storage conditions
Recommended Storage Temperature: Store in tightly closed containers away from excessive heat and moisture.
FIRST AID MEASURES of D PANTHENOL (VITAMIN B5):
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of D PANTHENOL (VITAMIN B5):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of D PANTHENOL (VITAMIN B5):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of D PANTHENOL (VITAMIN B5):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of D PANTHENOL (VITAMIN B5):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of D PANTHENOL (VITAMIN B5):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available
