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D-PANTHENOL

D-Panthenol is typically viscous and in liquid.
D-Panthenol is an alcohol derivative of vitamin B5, or pantothenic acid. 
D-Panthenol is a stable, water-soluble, light ingredient that readily penetrates the skin. 

CAS Number: 81-13-0
Molecular Formula: C9H19NO4
Molecular Weight: 205.25
EINECS Number: 201-327-3

D-Panthenol belongs to a derivative of pantothenic acid (vitamin B5). 
D-Panthenol can penetrate the skin and mucous membrane to be quickly oxidized to pantothenic acid. 
The later one is extremely hygroscopic and binds water effectively. 

Therefore, D-Panthenol can be used as a moisturizer. 
D-Panthenol is added to pharmaceutical and cosmetic products to relieve itching and improve wound healing. 
In ointments, D-Panthenol can be used for the treatment of sunburns, mild burns, minor skin injuries and disorders. 

D-Panthenol is also immediately applied after major abdominal surgery to minimize the possibility of paralytic ileus. 
In addition, D-Panthenol can also be supplemented into the commercial shampoos and hair conditioners to lubricate the hair shaft and give the hair a shiny appearance. 
The exact mechanism of action of D-Panthenol is still unclear, perhaps through its enhancing effect on acetylcholine.  

D-Panthenol is an alcohol analog of pantothenic acid and an important component of parenterals, local cosmetic preparations and multi-vitamins. 
D-Panthenol has as much biological activity as pantothenic acid and is found to be stable in aqueous solution.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

D-Panthenol is the alcohol analog of pantothenic acid (vitamin B5).
D-Panthenol is a derivative of vitamin B5 (pantothenic acid). 
D-Panthenol is a water-soluble, provitamin form of vitamin B5 that is commonly used in various cosmetic and pharmaceutical products for its skin and hair benefits. 

D-Panthenol is the alcohol analogue and biological precursor of D-pantothenic acid. 
These analogues are precursors in the biosynthesis of coenzyme A. 
D-Panthenol and D-Pantothenic acid are used in a variety of skin protection products. 

D-pantothenic acid may have a role in controlling keratinocyte proliferation and differentiation. 
D-Panthenol may be used for studies of skin protection emulsions from UV irradiation and as a humectant.
D-Panthenol is the alcohol analog of pantothenic acid (vitamin B5), and is thus a provitamin of B5. 

In organisms, D-Panthenol is quickly oxidized to pantothenic acid. 
D-Panthenol is a viscous transparent liquid at room temperature. 
D-Panthenol is used in pharmaceutical and cosmetic products as a moisturizer and to improve wound healing.

D-Panthenol is the provitamin of D-pantothenic acid. 
D-Panthenol, also known as pro-vitamin B5, is valued in skin and hair care for its moisturising properties and strengthening and moisturising conditioner for hair care products, especially conditioners. 
D-Panthenol is hygroscopic, since it acts as a humectant and adheres strongly to the cuticle and penetrates deep into the cortex of the hair shaft, thus improving the resistance of hair to mechanical stress.

D panthenol also known as Vitamin B5 works as a skin moisturizer, keeps skin smooth, soft and healthy.
D-Panthenol reinforces the skin barrier by reducing trans epidermal water loss, regenerates healthy skin maintaining cell stemness and has very good compatibility with different cosmetics ingredients and actives.
D-Panthenol is a B vitamin precursor (pro-vitamin B5) and substantially involved in regenerative metabolic processes of the skin. 

D-panthenol itself has no cosmetic effect but becomes active when it is converted into the cosmetically effective pantothenic acid. 
Because of its high compatibility, it is often used for baby care products, also in healing diaper creams. 
D-Panthenol has a moisture-binding, anti-inflammatory, regenerative and healing effect. 

D-Panthenol also strengthens the barrier function of the skin and improves its elasticity, promoting new cell formation in wounds. 
D-Panthenol is an alcohol derivative of vitamin B5, which is also known as Pantothenic Acid. 

D-Panthenol and pantothenic acid have the same biological activity and panthenol can be converted by oxidation to vitamin B5 in the skin. 
D-Panthenolic acid is found in all living cells and is essential for normal metabolism and hormone production.
D-Panthenol is an alcohol analog of pantothenic acid (Vitamin B5), and thus a provitamin of B5. 

D-Panthenol is an odorless, transparent, highly viscous, and colorless liquid at room temperature. 
D-Panthenol is frequently included in skincare products like creams, lotions, and ointments due to its moisturizing and soothing properties. 
D-Panthenol can help improve skin hydration, reduce redness and inflammation, and promote the healing of minor skin irritations and wounds.

D-Panthenol is often found in shampoos, conditioners, and hair treatments. 
D-Panthenol can help strengthen hair, reduce breakage, and improve hair texture. 
D-Panthenol is also believed to add moisture to the hair shaft, making hair look shinier and more manageable.

Due to its skin-soothing and regenerative properties, D-Panthenol is used in products designed to support wound healing, such as creams and ointments for minor burns, cuts, and abrasions.
D-Panthenol-containing products may be applied to sunburned skin to provide relief from the discomfort associated with sunburn. 
D-Panthenol can help soothe the skin and promote healing.

Some diaper rash creams and ointments contain D-Panthenol to help protect and soothe a baby's delicate skin in the diaper area.
D-Panthenol is used in cosmetics like foundations and powders to provide a smoother application and a more even skin tone.
D-Panthenol can also be taken as a dietary supplement, although it is not commonly used this way. 

In supplement form, D-Panthenol may be used to support overall skin health and wound healing from the inside out.
D-Panthenol-containing creams or ointments are sometimes recommended for tattoo aftercare. 
They can help keep the tattooed area moisturized, reduce itching, and support the healing process.

D-Panthenol is used in lip balms and lip care products to moisturize and protect the delicate skin on the lips, preventing dryness and chapping.
Some nail and cuticle creams or treatments include D-Panthenol to hydrate and strengthen nails and the surrounding skin.
D-Panthenol is found in some anti-aging skincare products due to its ability to improve skin texture, maintain moisture, and reduce the appearance of fine lines and wrinkles.

D-Panthenol may be used in scar management products to help minimize the appearance of scars after surgery or injury.
In ophthalmic preparations, D-Panthenol can be used to alleviate dry or irritated eyes by providing moisture and soothing effects.
Some oral care products, such as mouthwashes and toothpaste, may contain D-Panthenol to help maintain healthy gums and oral tissues.

D-Panthenol can be found in some intimate hygiene products designed to soothe and moisturize the vaginal area.
In addition to diaper rash creams, D-Panthenol may be used in baby care products like nappy creams to protect and nourish a baby's skin.
Dermatologists and healthcare professionals may recommend D-Panthenol-based products for post-procedural care following dermatological treatments such as chemical peels or laser procedures. 

D-Panthenols can help soothe and hydrate the skin during the recovery process.
D-Panthenol is the pro-vitamin of D-Pantothenic acid (Vitamin B5) for use in hair, skin and nail care products. 
D-Panthenol acts as a skin conditioning agent to provide deep penetrating moisture to the skin, stimulating epithelisation to provide wound healing and anti-inflammatory effects. 

D-Panthenol also functions as a hair conditioning agent to provide long lasting moisture to hair, preventing damage, thicken hair and improve luster and sheen.
D-Panthenol comes from vitamin B5 and is a moisturizing compound. 
D-Panthenol can come from either animal or plant sources.

D-Panthenol can be found in the ingredients in hair conditioners or body wash.
D-Panthenol is used commonly in skincare and cosmetic products.
D-Panthenol is the alcohol corresponding to pantothenic acid, of the vitamin B5 group. 

D-Panthenol is used as a food additive, and in skin and hair products as a conditioning agent.
D-Panthenol has been suggested for use in intestinal atony or distension, postoperative retention of flatus and feces, prophylaxis and treatment of paralytic ileus after abdominal surgery or traumatic injuries, equine colic (not due to mechanical obstruction) and any other condition when there is an impairment of smooth muscle function. 

D-Panthenol controlled studies are lacking with regard to proving the efficacy of the drug for any of these indications.
D-Panthenol readily penetrates into the skin and mucous membranes (including the intestinal mucosa), where it is quickly oxidized to pantothenic acid. 

D-Panthenolic acid is extremely hygroscopic.
D-Panthenol is also used in the biosynthesis of coenzyme A, which plays a role in a wide range of enzymatic reactions and in cell growth.
D-Panthenol is an odourless, slightly bitter, highly viscous, transparent, and colourless liquid at room temperature, but salts of pantothenic acid (for example sodium pantothenate) are powders that are typically white. 

D-Panthenol is easily soluble in water and alcohol, moderately soluble in diethyl ether, soluble in chloroform (1:100), in propylene glycol, and slightly soluble in glycerin.
D-Panthenol's expanded chemical formula is HO–CH2–C(CH3)2–CH(OH)–CONH–CH2CH2CH2–OH

Melting point: 64~69℃
alpha: 30.5 º (c=5, H2O on anh. sub)
Boiling point: 118-120 °C (2.7 mmHg)
Density: 1.20 g/mL at 20 °C (lit.)
vapor pressure: 0Pa at 25℃
refractive index: 1.495-1.502
Flash point: 118-120°C/0.02m
storage temp.: 2-8°C
solubility: DMSO (Sparingly), Methanol (Slightly), Water (Sparingly)
pka: 13.03±0.20(Predicted)
form: Viscous Liquid or Semi Solid
color: Clear colorless to slightly yellow
PH: pH (100g/l,25℃) : 8.5~10.5
optical activity: [α]20/D +30±1°, c = 5% in H2O
Water Solubility: soluble
Sensitive: Hygroscopic
Merck: 14,2947
BRN: 1724947
InChIKey: SNPLKNRPJHDVJA-ZETCQYMHSA-N
LogP-1.06 at 22℃

D-Panthenol, also known as provitamin B5, is the biologically active precursor of vitamin B5 (pantothenic acid). 
A major physiological function of vitamin B5 is its conversion to acetyl coenzyme A (acetyl CoA), which participates in many metabolic processes involving carbohydrates, lipids, and proteins. 
D-Panthenol is essentially the alcohol form of vitamin B5.

D-Panthenol is most well known for its humectant properties—it is hygroscopic—thereby leading to its inclusion in moisturizing formulations. 
Several reports in the literature highlight panthenol’s moisturizing properties and ability to improve the appearance and physical properties (e.g., smoothness) of skin.
D-Panthenol has a long history of use in cosmetic products and good toxicological profile.

D-Panthenol, also known as Pro-vitamin B5, is an active ingredient that can drastically improve the appearance of hair, skin and nails. 
Heirloom's d-Panthenol is the perfect ingredient for sophisticated body and hair care products.
D-Panthenol is great for treating minor wounds such as those caused by shaving and scratches to the skin. 

D-Panthenols anti-inflammatory effect first soothes, then helps prevent damaged skin. 
D-Panthenol is an antibacterial soothing and moisturising serum that supports healthy skin renewal. 
D-Panthenols formula is ideal for promoting the repair of dry, irritated skin by calming affected areas and reducing itching sensations to accelerate the healing process.

D-Panthenol is the alcohol analogue and biological precursor of D-pantothenic acid. 
These analogues are precursors in the biosynthesis of coenzyme A. D-Panthenol and D-Pantothenic acid are used in a variety of skin protection products. 
D-pantothenic acid may have a role in controlling keratinocyte proliferation and differentiation.

D-Panthenol is used in pet grooming products, such as shampoos and conditioners, to help improve the condition of a pet's coat and skin. 
D-Panthenol can be beneficial for pets with dry or irritated skin.
In some nasal sprays, D-Panthenol is included to provide moisture and relief to dry or irritated nasal passages, especially in dry climates or during periods of illness.

D-Panthenol may be added to antiseptic creams to help soothe and protect the skin around minor wounds or cuts.
Some products designed for managing eczema and psoriasis symptoms contain D-Panthenol to alleviate itching and inflammation while moisturizing the affected skin.
D-Panthenol is commonly included in after-sun lotions and creams to cool and hydrate the skin after exposure to the sun.

Hair gels, mousses, and sprays may contain D-Panthenol to help with styling while maintaining hair moisture and flexibility.
D-Panthenol is sometimes used in hair serums and leave-in conditioners to help prevent split ends and improve overall hair health.
D-Panthenol is found in some burn care products, including creams and gels, to provide relief and support healing for minor burns.

Some contact lens solutions contain D-Panthenol to provide moisture and comfort to the eyes when wearing contact lenses.
D-Panthenol is available in oral supplement form, often combined with other vitamins and minerals, to support hair and nail health from within the body.
D-Panthenol creams are sometimes used in radiation therapy to alleviate skin irritation and dryness caused by the treatment.

D-Panthenol is used as a cosmetic ingredient in various formulations to enhance the overall quality and performance of cosmetic products.
D-Panthenol is a chemical substance made from pantothenic acid, also known as vitamin B-5. 
D-Panthenol occurs organically and can also be produced from both plant and animal sources. 

D-Panthenol’s used as an additive in various cosmetic products around the globe.
D-Panthenol takes the form of either a white powder or a transparent oil at room temperature. 
In topical cosmetics, product manufacturers often used-panthenolas a moisturizer. 

D-Panthenol’s also included in many cosmetics as a softening, soothing, and anti-irritant agent. 
D-Panthenol is essential for a healthy diet, skin, and hair. 
D-Panthenol makes sense that panthenol, its derivative, is a staple of many skin care products, such as lotions and cleansers. 

D-Panthenol’s also found in cosmetics as various as lipstick, foundation, or even mascara.
D-Panthenol also appears in creams made to treat insect bites, poison ivy, and even diaper rash.
The National Center for Biotechnology Information listsd-panthenolas a skin protectant with anti-inflammatory properties. 

D-Panthenol can help improve skin’s hydration, elasticity, and smooth appearance. 
D-Panthenol also soothes: red skin, inflammation, little cuts or sores like bug bites or shaving irritation.
D-Panthenol helps with wound healing, as well as other skin irritations like eczema.

D-Panthenol can also help protect your hair from styling or environmental damage by locking in moisture.
One study found that D-Panthenol may help slow down and hide the look of thinning hair. 
One study found that applyingd-panthenolto the nail can help hydrate the nail and prevent breakage.

Both the U.S. Food and Drug Administration (FDA) and the European Commission on Cosmetic Ingredients have approvedpanthenolfor use in cosmetics. 
The National Institutes of Health (NIH) classifiesd-panthenolas “possibly safe” for general topical applications and nasal sprays. 
D-Panthenol’s listed as “likely safe” for topical use by children.

The FDA currently D-Panthenol its widely known “Generally Regarded as Safe” database for when it’s ingested as a food ingredient, or as a supplement. 
Although D-Panthenol’s widely considered beneficial as a supplement, it’s only classified as “likely safe” for topical use on the skin, hair, and nails. 
That means there’s no significant evidence thatd-panthenolcauses harm, and plenty of anecdotal evidence that it’s helpful for many skin concerns. 

But there isn’t enough evidence to be sure, so the FDA suggests that more research is needed.
The Cosmetic Ingredient Review (CIR), another reputable organization that protects consumers, assembled a panel of experts in 2017 to assess panthenol’s topical safety in light of recent research.
D-panthenol belongs to a derivative of pantothenic acid (vitamin B5). It can penetrate the skin and mucous membrane to be quickly oxidized to pantothenic acid. 

The later one is extremely hygroscopic and binds water effectively. 
Therefore, D-Panthenol can be used as a moisturizer. 
D-Panthenol is added to pharmaceutical and cosmetic products to relieve itching and improve wound healing. 

In ointments, D-Panthenol can be used for the treatment of sunburns, mild burns, minor skin injuries and disorders. 
D-Panthenol is also immediately applied after major abdominal surgery to minimize the possibility of paralytic ileus. 
In addition, it can also be supplemented into the commercial shampoos and hair conditioners to lubricate the hair shaft and give the hair a shiny appearance. 

The exact mechanism of action of D-panthenol is still unclear, perhaps through its enhancing effect on acetylcholine.
D-Panthenol’s hard to prove anything is unequivocally safe even with extensive testing. Even then, any time you decide whether or not to use a product, you should weigh the benefits against the risk for side effects.

That said, most of the research now available ond-panthenolsuggests that using a concentration 5 percent and under in a topical skin, hair, or nail product presents a very low risk to consumers. 
And the instance of negative side effects, like contact dermatitis, is very low.
In pharmaceuticals, cosmetics and personal-care products, D-Panthenol is a moisturizer and humectant, used in ointments, lotions, shampoos, nasal sprays, eye drops, lozenges, and cleaning solutions for contact lenses.

In ointments D-Panthenol is used for the treatment of sunburns, mild burns, minor skin injuries and disorders (in concentrations of up to 2–5%).
D-Panthenol improves hydration, reduces itching and inflammation of the skin, improves skin elasticity, and accelerates epidermal wounds' rate of healing.
For this purpose, D-Panthenol is sometimes combined with allantoin.

D-Panthenol binds to the hair shaft readily; so, it is a common component of commercial shampoos and hair conditioners (in concentrations of 0.1–1%). 
D-Panthenol coats the hair and seals its surface,[citation needed] lubricating the hair shaft and giving it a shiny appearance.
D-Panthenol is also recommended by tattoo artists as a post-tattooing moisturising cream.

D-Panthenol readily penetrates into the skin and mucous membranes (including the intestinal mucosa), where it is quickly oxidized to pantothenic acid. 
Pantothenic acid is extremely hygroscopic, that is, it binds water effectively. 
D-Panthenol is also used in the biosynthesis of coenzyme A, which plays a role in a wide range of enzymatic reactions and thus in cell growth Panthenol is an odourless, slightly bitter, highly viscous, transparent and colourless liquid at room temperature, but salts of pantothenic acid (for example sodium pantothenate) are powders (typically white). 

D-Panthenol is easily soluble in water and alcohol, moderately soluble in diethyl ether, soluble in chloroform (1:100), in propylene glycol, and slightly soluble in glycerin.
D-Panthenol's expanded chemical formula is HO–CH2–C(CH3)2–CH(OH)–CONH–CH2CH2CH2–OH.Panthenol comes in two enantiomers, D and L. Only D-panthenol (D-Panthenol) is biologically active, however both forms have moisturizing properties. 

For cosmetic use,d-panthenolcomes either in D form, or as a racemic mixture of D and L (dL-panthenol).
D-Panthenol is soluble in water, freely soluble in ethanol, slightly soluble in ether, and insoluble in fats and oils.
D-Panthenol is fairly stable to air and light. It is hygroscopic and sensitive to heat; heating to over 70 °C may cause racemization. 

However, D-Panthenol may be heated to 40 °C for short periods in order to improve flowability. 
D-Panthenol may be stored for 36 months from the date of manufacture in the unopened original container and at a temperature below 25 °C. The ‘best use before’ date is printed on the label. 
In aqueous solutions, D-Panthenol is markedly more stable than the salts of pantothenic acid, in particular at a pH of 3 to 6.

D-Panthenol is not intended for use in the manufacture of sterile drug products. 
The purchaser assumes all responsibility for additional processing, testing, labelling and registration required for such use.

D-Panthenol meets all requirements of the USP, FCC and Ph. Eur. when tested according to these compendia.
D-Panthenol is safe for the intended use. Avoid ingestion or direct contact by applying suitable protective measures and personal hygiene.

Uses Of D-Panthenol:
D-Panthenol may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques as well as partial least-squares multivariate calibration.
In pharmaceuticals, cosmetics, and personal-care products, D-Panthenol is a moisturizer and humectant, used in ointments, lotions, shampoos, nasal sprays, eye drops, lozenges, and cleaning solutions for contact lenses.

In ointments D-Panthenol is used for the treatment of sunburns, mild burns, minor skin injuries, and disorders (in concentrations of up to 2–5%).
D-Panthenol improves hydration, reduces itching and inflammation of the skin, improves skin elasticity, and accelerates epidermal wounds' rate of healing.
For this purpose, D-Panthenol is sometimes combined with allantoin.

D-Panthenol binds to the hair shaft readily, so, it is a common component of commercial shampoos and hair conditioners (in concentrations of 0.1–1%). 
D-Panthenol coats the hair and seals its surface,[citation needed] lubricating the hair shaft and giving it a shiny appearance.
D-Panthenol is widely used in cosmetic products as it is so effective in Skin and Hair preparations, often called Pro Vitamin B5, once in the skin it rapidly converts to vitamin B5 (Pantothenic Acid) which is a major constituent of Coenzyme A and has a key role in the repair mechanism of cells and tissues.

D-Panthenol is used as a moisturizer and humectant in cosmetics and personal care products. 
D-Panthenol is found in lotions, ointments, nasal sprays, eye drops, cleaning solutions for contact lenses, etc. 
D-Panthenol is widely used in skincare, haircare, and cosmetic products for its moisturizing, soothing, and skin-conditioning properties. 

D-Panthenol can be found in lotions, creams, serums, shampoos, conditioners, lip balms, and makeup products.
D-Panthenol is used in wound care products to promote the healing of minor cuts, scrapes, and burns. 
D-Panthenol can be found in ointments, creams, and dressings designed for this purpose.

D-Panthenol is commonly added to hair products to strengthen and moisturize hair. 
D-Panthenol can improve hair texture, reduce split ends, and enhance overall hair health.
In after-sun lotions and creams, D-Panthenol helps soothe and moisturize the skin after exposure to the sun, providing relief from sunburn and helping to prevent skin damage.

D-Panthenol is found in diaper creams and ointments to protect and soothe a baby's sensitive skin in the diaper area.
Pet shampoos, conditioners, and grooming products often contain D-Panthenol to improve the condition of a pet's coat and skin.
D-Panthenol can be used in pharmaceutical formulations, particularly in topical medications and creams designed to treat skin conditions and irritations.

Some eye drops and ophthalmic preparations contain D-Panthenol to provide relief from dry or irritated eyes.
D-Panthenol can be found in mouthwashes, toothpaste, and oral care products to support gum health and soothe oral tissues.
Nail and cuticle creams and treatments may include D-Panthenol to hydrate and strengthen nails and the skin around them.

D-Panthenol is commonly found in diaper rash creams and ointments for babies. 
D-Panthenol helps protect and soothe a baby's delicate skin in the diaper area, preventing and alleviating diaper rash.
D-Panthenol can be included in eye drops and eye care products to provide relief from dry eyes and irritation. 

D-Panthenol helps maintain moisture on the eye's surface.
D-Panthenol is used in nasal sprays to moisturize and soothe dry or irritated nasal passages, offering relief from congestion and discomfort.
D-Panthenol-containing creams and gels are sometimes used for burn care, particularly for minor burns. 

D-Panthenol helps cool and hydrate the skin and promotes the healing of burn injuries.
D-Panthenol is used in products designed for scar management. 
D-Panthenol can help minimize the appearance of scars, particularly when applied to healing wounds.

Some intimate hygiene products for women contain D-Panthenol to soothe and moisturize the vaginal area, providing comfort and protection.
D-Panthenol can be found in some oral care products, such as mouthwashes and toothpaste. I
D-Panthenol may help maintain healthy gums and oral tissues.

In the context of radiation therapy for cancer treatment, D-Panthenol creams and ointments are used to alleviate skin irritation and dryness caused by the radiation.
D-Panthenol is used as a cosmetic ingredient in various formulations to enhance the overall quality and performance of cosmetic products, including makeup, skincare, and haircare.
Some anti-aging skincare products contain D-Panthenol due to its ability to improve skin texture, retain moisture, and reduce the appearance of fine lines and wrinkles.

D-Panthenol is added to pet grooming products like shampoos and conditioners to enhance the condition of a pet's coat and skin.
D-Panthenol can be found in hair serums and leave-in conditioners to help prevent split ends and improve overall hair health.
D-Panthenol-containing products are recommended for tattoo aftercare. They assist in keeping the tattooed area moisturized and reducing itching and discomfort during the healing process.

Some skincare products designed for managing eczema and psoriasis symptoms include D-Panthenol to alleviate itching, inflammation, and dryness.
D-Panthenol-containing gels or oral sprays are used to provide relief from mouth ulcers and canker sores. 
D-Panthenol can help soothe and promote healing of the affected oral tissues.

D-Panthenol is included in some foot care products to moisturize and soften dry, cracked skin on the feet. 
D-Panthenol can be particularly useful for those with rough or calloused heels.
In healthcare settings, D-Panthenol-containing creams or ointments may be used for perineal care to protect and soothe the delicate skin in the genital and rectal areas, especially for bedridden patients or those in long-term care.

Some shaving creams, gels, and aftershaves contain D-Panthenol to provide a smoother and less irritating shaving experience. 
D-Panthenol helps reduce razor burn and soothes the skin after shaving.
D-Panthenol is occasionally found in products aimed at preventing or reducing the appearance of stretch marks, particularly during pregnancy or periods of weight change.

D-Panthenol creams or lotions can help provide relief from various forms of dermatitis, including contact dermatitis and allergic skin reactions.
D-Panthenol-containing products may be used to alleviate itching and discomfort associated with insect bites and stings.
D-Panthenol is a common ingredient in hand creams and lotions, helping to keep the hands moisturized and protected, especially in dry or cold weather.

Some scalp treatments and shampoos include D-Panthenol to improve the overall health of the scalp, reduce dryness, and promote healthy hair growth.
D-Panthenol may be included in first aid kits for its versatility in treating various minor injuries, skin conditions, and discomforts.
Orthodontic wax and dental products sometimes contain D-Panthenol to provide relief from irritation caused by braces, wires, or dental appliances.

In healthcare settings, D-Panthenol creams or ointments are used to help prevent and manage pressure sores (bedsores) in bedridden or immobile patients.
D-Panthenol can be found in some eye creams to reduce puffiness and promote skin elasticity around the eyes.
D-Panthenol is a key ingredient in anti-itch creams and lotions, providing relief from itching caused by various skin condSitions, including allergies and rashes.

Safety Profile Of D-Panthenol:
Some individuals may be sensitive or allergic to D-Panthenol. 
D-Panthenol-containing products should be kept away from the eyes. 
If the D-Panthenol accidentally comes into contact with the eyes, rinse thoroughly with water and seek medical attention if irritation persists.

D-Panthenol is generally safe when used topically but should not be ingested. 
If ingested accidentally, seek medical attention.
While D-Panthenol is known for its skin-soothing properties, there is a rare possibility that it may cause skin irritation in some individuals.

In some cases, D-Panthenol may be incompatible with certain skincare ingredients or formulations. 
Consult the product label or a healthcare professional for guidance on product compatibility.

Synonyms Of D-Panthenol:
D-Panthenol
D-Panthenol
81-13-0
Pantothenol
Ilopan
D-Pantothenyl alcohol
Bepanthen
Bepanthene
Bepantol
Pantol
Provitamin B
Panthoderm
Thenalton
Motilyn
Panadon
Zentinic
(+)-Panthenol
d-Pantothenol
Pantothenyl alcohol
Cozyme
D-P-A Injection
D(+)-Panthenol
Pantenyl
Synapan
Urupan
Intrapan
D(+)-Pantothenyl alcohol
D-Panthenol 50
Provitamin B5
Dexpantenol
Pantothenylol
d panthenol
(2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
(R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
D-Panthenolum
Penthenol
Varitan
Alcopan-250
Dextro pantothenyl alcohol
Propanolamine, N-pantoyl-
N-Pantoyl-propanolamine
Sinecort
Pantothenol, D-
Panthenol (D)
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-
Panthenol, (+)-
N-Pantoyl-3-propanolamine
D-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide
UNII-1O6C93RI7Z
Panthenol (JAN)
Prestwick_529
D-Panthenol (1.20 g/mL)
NSC 302962
Ilopan (TN)
CORNERGEL
D-(+)-Panthenol
DOLOBENE
1O6C93RI7Z
CCRIS 3947
HSDB 296
DTXSID3022906
CHEBI:27373
PANTHENOL 50W
EINECS 201-327-3
PANTHENOL, (R)-
ALCOPAN 250
D-(+)-Pantothenyl alcohol
BAY 81-2996
BRN 1724947
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (R)-
Butyramide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, D-(+)-
DTXCID402906
2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide, (R)-
EC 201-327-3
2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide, D-(+)-
4-04-00-01652 (Beilstein Handbook Reference)
D-Panthenol [USAN:USP:INN:BAN]
NSC302962
NSC-302962
component of Pantho-F
NCGC00142622-03
PANTHENOL [JAN]
d(+)-2,4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethylbutyramide
(R)-2,4-Dihydroxy-N-(3-hydroxy-propyl)-3,3-dimethylbutanamide
alpha,gamma-Dihydroxy-N-(3-hydroxypropyl)-beta,beta-dimethylbutyramide, D-(+)-
D(+)-alpha,gamma-Dihydroxy-N-(3-hydroxypropyl)-beta,beta-dimethylbutyramide
Dexpantenol [INN-Spanish]
D-Panthenolum [INN-Latin]
D-Panthenol (MART.)
D-Panthenol [MART.]
D-Panthenol (USP-RS)
D-Panthenol [USP-RS]
D-Panthenol (EP MONOGRAPH)
D-Panthenol [EP MONOGRAPH]
(R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide
D-Panthenol (USP MONOGRAPH)
D-Panthenol [USP MONOGRAPH]
pantothenylol alcohol
component of Zentinic
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (theta)-
D-Panthenol [USAN]
D-Panthenol [USAN:BAN:INN]
dexpantenolo
(R)-2,4-Dihydroxy-3,3-dimethylbutyric 3-hydroxypropylamide
C9-H19-N-O4
D-Panthenol;
Fancol DL
CAS-81-13-0
NCGC00186658-01
D-Panthenol (USP)
MFCD00065006
Panthenol, (+ )-
Prestwick0_000022
Prestwick1_000022
Prestwick2_000022
Prestwick3_000022
D-Panthenol (USP/INN)
D-Panthenol [MI]
compnent of ilopan-Choline
D-Panthenol [FCC]
D-Panthenol [INN]
bmse000445
D-Panthenol [HSDB]
D-PANTHENOL [VANDF]
D-Panthenol [VANDF]
SCHEMBL15861
BSPBio_000083
D-Panthenol [WHO-DD]
SPBio_002004
BPBio1_000093
Butanamida, 2,4-dihidroxi-n-(3-hidroxipropil)-3,3-dimetil-, (2r)-
CHEMBL1200979
D(+)alpha,gamma-dihydroxy-N-(3-hydroxypropyl)-beta,beta-dimethylbutyramide
SCHEMBL20553090
A11HA30
D03AX03
S01XA12
D-Panthenol [ORANGE BOOK]
HMS1568E05
HMS2094E09
HMS2095E05
HMS3712E05
(+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide
HY-B1391
D-Panthenol, >=98.0% (NT)
Tox21_111563
LMFA08020198
s4695
AKOS015841507
AKOS015901947
Tox21_111563_1
CCG-213429
CS-8175
DB09357
NCGC00142622-01
NCGC00142622-04
AS-14732
D-Panthenol 10 microg/mL in Acetonitrile
D-Panthenol, tested according to Ph.Eur.
SBI-0206936.P001
D-Panthenol, Vetec(TM) reagent grade, 98%
P0692
C05944
D00193
D70909
EN300-7414583
Q-201048
Q47495755
A6CF1A81-5B98-4C28-A379-EA28FA9DD210
(R)-3-(2,4-Dihydroxy-3,3-dimethylbutyramido)-1-propanol
2,4-Dihydroxy-N-(3-hydroxy-propyl)-3,3-dimethylbutanamide
D-Panthenol, European Pharmacopoeia (EP) Reference Standard
(2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-butanamide
(R)-()-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide
(R)-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
(R)-2,4-dihydroxy-3,3-dimethyl-N-(3-hydroxypropyl)-butanamide
(R)-2,4-Dihydroxy-N-(3-hydroxy-propyl)-3,3-dimethyl-butyramide
D-(+)-2,4-Dihydroxy-3,3-dimethyl-N-(3-hydroxypropyl)butyramide
d-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl butyramide
D-Panthenol, >=98% (perchloric acid titration), >=98% (TLC)
D-Panthenol, United States Pharmacopeia (USP) Reference Standard
(D)-(+)-2, 4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide
D(+)-.ALPHA.,.GAMMA.-DIHYDROXY-N-(3-HYDROXYPROPYL)-.BETA.,.BETA.-DIMETHYLBUTYRAMIDE
D-Panthenol, Pharmaceutical Secondary Standard; Certified Reference Material
1113-70-8

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