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D5 (cyclopentasiloxane) is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom.
D5 (cyclopentasiloxane) is used in the production of some silicon-based polymers that are widely used in various personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
CAS: 541-02-6
MF: C10H30O5Si5
MW: 370.77
EINECS: 208-764-9
D5 (cyclopentasiloxane) is a silicone regularly used in cosmetic products.
D5 (cyclopentasiloxane)’s commonly found in medical implants, sealants, lubricants, and windshield coatings.
D5 (cyclopentasiloxane) is colorless, odorless, non-greasy, and water-thin.
D5 (cyclopentasiloxane) doesn’t get absorbed into the skin.
Rather,D5 (cyclopentasiloxane) evaporates quickly away from it.
This property makes D5 (cyclopentasiloxane) a useful ingredient in cosmetic products that need to dry quickly, like antiperspirants and hair sprays.
D5 (cyclopentasiloxane) also has lubricating properties.
This gives a slippery and silky feeling when applied to the skin and hair and allows D5 (cyclopentasiloxane) to spread more easily.
As if the name "D5 (cyclopentasiloxane)" wasn't hard enough to say, we should point out that it's also known as decamethylcyclopentasiloxane.
But no need to stress—you can keep D5 (cyclopentasiloxane) simple and call it D5, its other commonly used name, for short.
D5 (cyclopentasiloxane) is described by Robinson as a silicon-based compound, and it's part of a larger category called cyclomethicone.
D5 (cyclopentasiloxane) functions primarily as an emollient, comes in a colorless and odorless liquid form, and is found in a vast array of beauty products from skincare to haircare.
D5 (cyclopentasiloxane) is often included in skin care formulations to improve the silky-smooth spreadabilty and sensorial feel of a product.
D5 (cyclopentasiloxane) is a lightweight silicone, whose appearance as a raw material is a clear, odorless fluid.
D5 (cyclopentasiloxane) also functions as a solvent to help improve the dispersion of cosmetic ingredients in a solution and improve delivery of key ingredients.
D5 (cyclopentasiloxane) is categorise as a volatile silicone, but it’s important to distinguish that the word volatile here doesn’t mean irritating to skin.
Instead, D5 (cyclopentasiloxane) means this kind of silicone evaporates quickly from skin’s surface, which is one of the advantages of formulating with cyclopentasiloxane as it is able to evenly distribute other key ingredients without leaving a heavy or occlusive feel.
The velvety film left behind is permeable, meaning D5 (cyclopentasiloxane) doesn’t suffocate skin.
D5 (cyclopentasiloxane), also known as D5, is an organosilicon compound with the formula [(CH3)2SiO]5.
D5 (cyclopentasiloxane) is a colorless and odorless liquid that is slightly volatile.
D5 (cyclopentasiloxane) is a staple ingredient used in cosmetics.
The chemical formula for D5 (cyclopentasiloxane) is C10H30O5Si5.
D5 (cyclopentasiloxane) is a non-greasy silicone that is colorless, odorless, and water-thin.
D5 (cyclopentasiloxane) gets quickly evaporated from the skin rather than getting absorbed - making it a brilliant ingredient to be used in products that need to dry fast, like antiperspirants and hair sprays.
Further, D5 (cyclopentasiloxane) also has lubricating properties and feels silky smooth when applied to hair and skin.
D5 (cyclopentasiloxane) is a high molecular weight, hydrophobic silicone fluid with a low vapor pressure.
D5 (cyclopentasiloxane) has a high resistance to hydrolysis by water and acids.
D5 (cyclopentasiloxane) is used as a reactive diluent in the synthesis of compounds that have an unsaturated bond.
D5 (cyclopentasiloxane) can also be used as a film-forming polymer in cosmetics and personal care products, such as hair sprays, body lotions, and antiperspirants.
D5 (cyclopentasiloxane) is used in the synthesis of butanediol, which is then converted into other materials like polyester or polysiloxanes.
D5 (cyclopentasiloxane) Chemical Properties
Melting point: -44°C
Boiling point: 90 °C/10 mmHg (lit.)
Density: 0.958 g/mL at 25 °C (lit.)
Vapor pressure: 33.2Pa at 25℃
Refractive index: n20/D 1.396(lit.)
Fp: 162 °F
Storage temp.: 2-8°C
Solubility: <0.0001g/l (calculated)
Form: Liquid
Specific Gravity: 0.959
Color: Colorless
Explosive limit: 0.52-7%(V)
Water Solubility: Immiscible with water.
Hydrolytic Sensitivity: 1: no significant reaction with aqueous systems
Merck: 14,2848
BRN: 1800166
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey: XMSXQFUHVRWGNA-UHFFFAOYSA-N
LogP: 8.07 at 24.6℃
CAS DataBase Reference: 541-02-6(CAS DataBase Reference)
NIST Chemistry Reference: D5 (cyclopentasiloxane) (541-02-6)
EPA Substance Registry System: D5 (cyclopentasiloxane) (541-02-6)
D5 (cyclopentasiloxane) is a silicone.
D5 (cyclopentasiloxane)’s also used as a sealant to protect the skin against moisture loss and as a lubricant as it helps the skin and hair absorb heavier, larger molecular weight ingredients.
D5 (cyclopentasiloxane) gives products a silky, smooth feel that then have a nice feel to the skin.
Also known as D5 (cyclopentasiloxane), thankfully, it’s often referred to as simply, D5.
D5 (cyclopentasiloxane)’s colourless, odourless and is always found in liquid form.
Uses
D5 (cyclopentasiloxane) used in cosmetic and personal care products.
D5 (cyclopentasiloxane) used in dermal exposure and inhalation toxicity study.
Intermediate in the manufacture of high mol wt siloxane polymers.
Carrier ingredient in personal care products; dry cleaning solvent.
D5 (cyclopentasiloxane) is incorporated into a formulation for its emollient and solvent activity.
Octamethylcyclotetrasiloxane and D5 (cyclopentasiloxane) are major industrial products, which are either marketed as such or used for the production of polydimethylsiloxanes.
D5 (cyclopentasiloxane) is known for being able to evaporate and dry quickly.
D5 (cyclopentasiloxane) are also known to repel water and glide easily.
D5 (cyclopentasiloxane) is why they are commonly used as ingredients in lubricants and sealants.
They are also known to form a protective barrier on the skin and hair.
D5 (cyclopentasiloxane) can help you detangle your hair, prevent breakage, and reduce frizz.
D5 (cyclopentasiloxane) sometimes appears on a label as decamethylcyclopentasiloxane or D5.
D5 (cyclopentasiloxane) may also be put under the broader category name of cyclomethicone.
D5 (cyclopentasiloxane)’s different from another siloxane known as dimethicone or polydimethylsiloxane (PDMS).
D5 (cyclopentasiloxane) is classified as a cyclomethicone.
Such fluids are commonly used in cosmetics, such as deodorants, sunblocks, hair sprays and skin care products.
D5 (cyclopentasiloxane) is becoming more common in hair conditioners, as it makes the hair easier to brush without breakage.
D5 (cyclopentasiloxane) is also used as part of silicone-based personal lubricants.
D5 (cyclopentasiloxane) is considered an emollient.
In Canada, among the volume used in consumer products approximately 70% were for antiperspirants and 20% for hair care products.
10,000–100,000 tonnes per year of D5 (cyclopentasiloxane) is manufactured and/or imported in the European Economic Area.
Atmospheric emissions of D5 (cyclopentasiloxane) in the Northern Hemisphere were estimated to 30,000 tonnes per year.
Skin care: The hydrating properties of D5 (cyclopentasiloxane) are great for the skin as it traps moisture, making the skin smooth and soft.
D5 (cyclopentasiloxane) is used in lightweight products as it does not penetrate the skin but rather evaporates quickly.
Further, D5 (cyclopentasiloxane) skin care has anti-aging properties and is a great ingredient to be used in lotions
Hair care:D5 (cyclopentasiloxane) is a great conditioner for hair because of its lubricating properties.
D5 (cyclopentasiloxane) is commonly used in shampoos, hair conditioners, hair sprays, anti-frizz, and hair detangling products.
D5 (cyclopentasiloxane) forms a layer on the hair, protecting and preventing it from damage while also allowing the product to spread easily and evenly.
Cosmetic products: D5 (cyclopentasiloxane) is used in makeup and makeup removers because it is non-comedogenic and does not block pores.
Production and Polymerization
Commercially D5 (cyclopentasiloxane) is produced from dimethyldichlorosilane.
Hydrolysis of the dichloride produces a mixture of D5 (cyclopentasiloxane) and polydimethylsiloxane.
From this mixture, the cyclic siloxanes including D5 (cyclopentasiloxane) can be removed by distillation.
In the presence of a strong base such as KOH, the polymer/ring mixture is equilibrated, allowing complete conversion to the more volatile cyclic siloxanes:
[(CH3)2SiO]5n → n [(CH3)2SiO]5
where n is a positive integer.
D4 and D5 (cyclopentasiloxane) are also precursors to the polymer.
The catalyst is again KOH.
Safety and Environmental Considerations
The LD50 for D5 (cyclopentasiloxane) in rats is >50 g/kg.
The environmental impacts of D5 (cyclopentasiloxane) and D4 have attracted attention because these compounds are pervasive.
D5 (cyclopentasiloxane) have been detected in some species of aquatic life.
A scientific review in Canada has determined that “D5 (cyclopentasiloxane) does not pose a danger to the environment” and a scientific assessment of D5 by the Australian government stated, "the direct risks to aquatic life from exposure to these chemicals at expected surface water concentrations are not likely to be significant."
However, in the European Union, D5 (cyclopentasiloxane) was characterized as a substance of very high concern (SVHC) due to its PBT and vPvB properties and was thus included in the candidate list for authorisation.
Since 31 January 2020, D5 (cyclopentasiloxane) cannot be placed on the market in the European Union in wash-off cosmetic products in a concentration equal to or greater than 0.1 % by weight.
Synonyms
DECAMETHYLCYCLOPENTASILOXANE
541-02-6
Cyclopentasiloxane, decamethyl-
Cyclomethicone 5
2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
Dimethylsiloxane pentamer
Dekamethylcyklopentasiloxan
CYCLOMETHICONE
Ciclopentasiloxane
Cyclomethicone D5
0THT5PCI0R
DTXSID1027184
Dow corning 345
NUC silicone VS 7158
Silicon SF 1202
Cyclopentasiloxane, 2,2,4,4,6,6,8,8,10,10-decamethyl-
Cyclic dimethylsiloxane pentamer
MFCD00046966
2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane
KF 995
VS 7158
D5-sil
CCRIS 1328
HSDB 5683
Dekamethylcyklopentasiloxan [Czech]
EINECS 208-764-9
UNII-0THT5PCI0R
Ddecamethylcyclopentasiloxane
decamethyl cyclopentasiloxane
SF 1202
BRN 1800166
C10H30O5Si5
D5 Cyclomethicone
D5
dimethylcyclopentasiloxane
Decamethylcylopentasiloxane
JEESILC CPS-211
EC 208-764-9
SCHEMBL28497
N-Propylheptamethyltrisiloxane
XIAMETER PMX-0245
4-04-00-04128 (Beilstein Handbook Reference)
DTXCID907184
CYCLOPENTASILOXANE (D5)
CHEMBL1885178
CYCLOPENTASILOXANE [INCI]
CHEBI:191092
Decamethylcyclopentasiloxane, 97%
CYCLOMETHICONE 5 [USP-RS]
CYCLOMETHICONE 5 [WHO-DD]
BCP15826
Tox21_303170
CD3770
KF-995
AKOS008901199
ZINC169743678
CS-W009767
DB11244
DOW CORNING ST CYCLOMETHICONE 5
DECAMETHYLCYCLOPENTASILOXANE [MI]
NCGC00163981-01
NCGC00257224-01
OCTAMETHYLCYCLOTETRASILOXANE (D5)
AS-59731
CAS-541-02-6
DECAMETHYLCYCLOPENTASILOXANE [HSDB]
KP-545 COMPONENT CYCLOMETHICONE 5
D1890
D3770
Decamethylcyclopentasiloxane (cyclic monomer)
FT-0665531
D78203
S05475
Decamethylcyclopentasiloxane, analytical standard
Q414350
decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
Cyclomethicone 5, United States Pharmacopeia (USP) Reference Standard
2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane #
D5 Cyclomethicone, Pharmaceutical Secondary Standard; Certified Reference Material
