PRODUCTS

D6 SILOXANE

D6 SILOXANE = DODECAMETHYLCYCLOHEXASILOXANE = D6 = CYCLOMETHICONE 6

CAS Number: 540-97-6
EC Number: 208-762-8
MDL number: MFCD00144215
Molecular Formula: C12H36O6Si6

D6 Siloxane, more commonly known as Dodecamethylcyclohexasiloxane, contains six repeating units of silicon (Si) and oxygen (O) atoms in a closed loop, giving it a "cyclic" structure.
When used as an intermediate during the manufacturing process, virtually all D6 Siloxane is consumed with only a tiny amount remaining in final products.

D6 Siloxane is an organosilicon compound.
D6 Siloxane, also known as D6, is an industrial chemical.
D6 Siloxane is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.

D6 Siloxane is Clear Colourless Liquid.
There is no known natural source of D6 Siloxane.
D6 Siloxane also known as cyclohexasiloxane or D6, belongs to a group of cyclic volatile methyl-siloxanes (cVMS) with relatively low molecular weight (< 600 g/mol) and high vapor pressure.

D6 Siloxane, (Dodecamethylcyclohexasiloxane), contains six repeating units of silicon (Si) and oxygen (O) atoms in a closed loop, giving it a “cyclic” structure.
The cyclosiloxanes octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), and D6 Siloxane (dodecamethylcyclohexasiloxane) are cyclic volatile methyl siloxane (cVMS) substances with four, five, and six siloxane groups, respectively.

A siloxane is a functional group in organosilicon chemistry with the Si−O−Si linkage.
The parent siloxanes include the oligomeric and polymeric hydrides with the formulae H(OSiH2)nOH and (OSiH2)n.
Siloxanes also include branched compounds, the defining feature of which is that each pair of silicon centres is separated by one oxygen atom.
The siloxane functional group forms the backbone of silicones, the premier example of which is polydimethylsiloxane.
The functional group R3SiO− (where the three Rs may be different) is called siloxy.

Cyclosiloxanes are basic members of the broad family of silicone materials.
All silicone materials share a common chemistry but each substance is different with regard to its properties and use.
D4, D5 and D6 Siloxane are the three cyclosiloxanes in commercial production and their use has been proven safe for human health and the environment.

This family includes several categories of substances:
*hexamethylcyclotrisiloxane (D3);
*octamethylcyclotetrasiloxane (D4);
*decamethylcyclopentasiloxane (D5);
*dodecamethylcyclohexasiloxane (D6)
*dodecamethylcycloheptasiloxane (D7).

The term "silicone" can also be used to refer to siloxanes.
Siloxanes, including the cyclic siloxanes octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), and D6 Siloxane (dodecamethylcyclohexasiloxane) are among the most extensively studied materials used in consumer and industrial applications today.

USES and APPLICATIONS of D6 SILOXANE:
-Cosmetic Uses:
*hair conditioning
*skin conditioning
*skin conditioning - emollient solvents

-D6 Siloxane is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
-D6 Siloxane is used in the following products: washing & cleaning products, polishes and waxes and cosmetics and personal care products.
-Other release to the environment of D6 Siloxane is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

-D6 Siloxane is used in the following products: cosmetics and personal care products, polishes and waxes, washing & cleaning products and semiconductors.
-D6 Siloxane is used in the following areas: health services and formulation of mixtures and/or re-packaging.
-D6 Siloxane is found or used in the manufacture of a wide variety of products.
-D6 Siloxane is a silicone-based emollient.

-A cyclic volatile methylsiloxane (cVMS) used in cosmetic and personal care products, D6 Siloxane can be used in dermal exposure and inhalation toxicity study.
-D6 Siloxanes are used as fragrance carriers or solvents in household products, personal care products, cleaning agents and as precursors in the manufacture of silicone polymers.

-D6 Siloxane is used in cosmetic and personal care products.
D6 Siloxane is Used in dermal exposure
-D6 Siloxane is used in cosmetic and personal care products.
-D6 Siloxane is used in dermal exposure and inhalation toxicity study.

-The most important worldwide use of D6 Siloxane is as an ingredient in the formulation of personal care products and as an intermediate in the production of polydimethylsiloxanes (PDMS) silicone polymers.
-The predominant use of D6 Siloxane worldwide and in Canada is in blending and formulating consumer products and manufacturing silicone polymers.

-D6 Siloxane is used in personal care products such as hair/skin care products, antiperspirants and deodorants.
-Biomedical uses of silicones include medical devices, blood-handling equipment, as a blood defoaming agent, as protective barriers, lubricants and as surface treatment of wound dressings.
-Silicone fluids containing D6 Siloxane have also been approved as active and non-active ingredients in pharmaceuticals in Canada, the most common use being in anti-flatulence drugs.

-D6 Siloxane is also used in industrial processes (as a defoamer, surfactant in certain pesticide products); in lubricants, cleaning products, sealants, adhesives, waxes, polishes and coatings.
-Siloxanes are manmade and have many commercial and industrial applications because of the compounds’ hydrophobicity, low thermal conductivity, and high flexibility.

-D6 Siloxane is an odorless, colorless liquid mostly used as an intermediate or basic raw material in the production silicone rubbers, gels and resins.
-D6 Siloxane can also be used as an ingredient in silicone mixtures used in cosmetic applications such as skin creams and deodorants, where D6 Siloxane may be labelled "cyclomethicone" or "cyclohexasiloxane".

-In personal care products, cyclosiloxanes act as “carriers”, allowing products to spread smoothly and easily and providing a silky feel during application.
-D6 Siloxane is an odorless, colorless liquid mostly used as an intermediate or basic raw material in the production silicone rubbers, gels and resins.
-D6 Siloxane can also be used as an ingredient in silicone mixtures used in cosmetic applications such as skin creams and deodorants.

-When D6 Siloxane is used as an intermediate during the manufacturing process, virtually all D6 Siloxane is consumed with only a tiny amount remaining in final products.
-D6 Siloxane can also be used as an ingredient in silicone mixtures used in cosmetic applications such as skin creams and sunscreen, where D6 Siloxane may be labelled “cyclomethicone” or “cyclohexasiloxane”.

-D6 Siloxane imparts several benefits in personal care formulations, such as silkiness for conditioners, extra volume in lip glosses, and easy application in deodorants.
This product has a D6 Siloxane content of 94%.
-Cyclosiloxanes are used in the manufacture of silicones, in combination or alone in personal care products, and as carriers, lubricants and solvents in a variety of commercial applications.

-Their use in cosmetics is one of their most important applications.
-D5 and D6 Siloxane are commonly used in cosmetics as emollients, hair and skin conditioning ingredients, and solvents.
-The ingredients can be used in hair conditioning products where the product is washed off when used or in skincare products, personal deodorants, and colour cosmetics where the product is left on the skin.

-Cyclic siloxanes are starting materials for silicone polymers and are used in detergents and cleaning agents, polishes, waxes, cosmetics and personal care products.
-D6 Siloxane is used Plasticizers, solvents, humectants, processing aids, lubricants, release agents, antifoams.

-Silicone compounds D4 (cyclotetrasiloxane), D5 (cyclopentasiloxane), and D6 Siloxane are often found in personal care products and flow into the environment along with waste water.
They are also important source materials for certain silicones and are often found as residues in finished products.

-Basic members of the broad family of silicone materials, all cyclotetrasiloxane (D4), cyclopentasiloxane (D5), D6 Siloxane are volatile oils with a cyclic chemical structure and various properties.
They are widely used because of the smooth and refreshing feeling they create.

-They are usually present in cosmetic products (make-up, cream, deodorant, etc.) and more widely in certain cleaning products or paints.
-Organosiloxanes are widely used in personal care products because they provide desirable properties in cosmetic products.
-These compounds are octamethylcyclotetrasiloxane (D4), decamethylcyclotetrasiloxane (D5) and D6 Siloxane (dodesamethylcyclotetrasiloxane).
These compounds are cyclic methyl siloxane substances containing four, five and six siloxane groups, respectively, and they have a mild and refreshing effect in cosmetic products.

PHYSICAL and CHEMICAL PROPERTIES of D6 SILOXANE:
Molecular Weight: 444.92
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 0
Exact Mass: 444.11274807
Monoisotopic Mass: 444.11274807

Topological Polar Surface Area: 55.4 Å²
Heavy Atom Count: 24
Formal Charge: 0
Complexity: 320
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

FIRST AID MEASURES of D6 SILOXANE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.

*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.

*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.

*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.

-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of D6 SILOXANE:
-Environmental precautions:
Do not let product enter drains.

-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of D6 SILOXANE:
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder

*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.

-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of D6 SILOXANE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:

*Eye/face protection:
Use Safety glasses

*Skin protection:
not required

*Respiratory protection:
Not required; except in case of aerosol formation.

-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of D6 SILOXANE:
-Precautions for safe handling:
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.

*Hygiene measures:
Change contaminated clothing.
Wash hands after working with substance.

-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.

STABILITY and REACTIVITY of D6 SILOXANE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .

-Possibility of hazardous reactions:
No data available

SYNONYMS:
DODECAMETHYLCYCLOHEXASILOXANE
Cyclohexasiloxane, dodecamethyl-
Cyclomethicone 6
2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
UNII-XHK3U310BA
XHK3U310BA
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane
HSDB 7723
dodecamethyl cyclohexasiloxane
SCHEMBL93785
DTXSID6027183
IUMSDRXLFWAGNT-UHFFFAOYSA-
CHEBI:191103
AKOS015839990
ZINC169794506
FS-5671
DB-008587
D2040
FT-0625566
S08515
T71035
Dodecamethylcyclohexasiloxane, analytical standard
A914553
Q27293843
UNII-NMQ347994Z component IUMSDRXLFWAGNT-UHFFFAOYSA-N
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane #
Cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane 95%
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane, 95%
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane, AldrichCPR
Cyclomethicone 6, United States Pharmacopeia (USP) Reference Standard
2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexa