Quick Search

PRODUCTS

DB (DENATONIUM BENZOATE PURE)

CAS Number: 3734-33-6
Molecular Weight: 446.58
Beilstein: 8179408
EC Number: 223-095-2
MDL number: MFCD00031578
PubChem Substance ID: 57654112

APPLICATIONS

The bitterness of the compound guides most applications of denatonium. 
DB (denatonium benzoate pure) is used to denature ethanol so that DB (denatonium benzoate pure) is not treated as an alcoholic beverage with respect to taxation and sales restrictions. 
One designation in particular, SD-40B, indicates that ethanol has been denatured using DB (denatonium benzoate pure).

Denatonium is commonly included in placebos used in clinical trials to mimic the bitter taste of certain medications.

DB (denatonium benzoate pure) also discourages consumption of poisonous alcohols such as methanol and additives such as ethylene glycol. 
DB (denatonium benzoate pure) is also added to many kinds of harmful liquids including solvents (such as nail polish remover), paints, varnishes, toiletries and other personal care items, special nail polish for preventing nail biting, and various other household products. 
DB (denatonium benzoate pure) is also added to less hazardous aerosol products (such as gas dusters) to discourage inhalant abuse of the volatile vapors.

In 1995, the U.S. state of Oregon required that DB (denatonium benzoate pure) be added to products containing sweet-tasting ethylene glycol and methanol such as antifreeze and windshield washer fluid to prevent poisonings of children and animals.
In December 2012, U.S. manufacturers voluntarily agreed to add DB (denatonium benzoate pure) to antifreeze sold nationwide.

Nintendo Switch game cards were coated in DB (denatonium benzoate pure) to prevent young children from consuming them.

DB (denatonium benzoate pure) is one of the most bitter substances known and is equally used for many other purposes. 
Indeed DB (denatonium benzoate pure) is one of the substances most used for the denaturing of alcohol (especially ethanol) in order to make it undrinkable and ready for industrial uses.

The bitterest compound known DB (denatonium benzoate pure) is used as an alcohol denaturant and flavor in pharmaceuticals. 
DB (denatonium benzoate pure) is also used in antifreeze, nail biting preventions, respirator mask fit-testing, animal repellents, liquid soaps and shampoos. 

Further, DB (denatonium benzoate pure) is used in air care products. 
DB (denatonium benzoate pure) acts as H1 antihistamine. 
In addition to this, DB (denatonium benzoate pure) is used as a disinfectant.

DB (denatonium benzoate pure) is the most bitter chemical compound known,used as aversive agents (bitterants) to prevent inappropriate ingestion. 
Also, DB (denatonium benzoate pure) is used in denatured alcohol, antifreeze, nail biting preventions, respirator mask fit-testing, animal repellents, liquid soaps, and shampoos.

One of the first and most important uses of DB (denatonium benzoate pure) was as an additive to methanol (methyl alcohol; wood alcohol). 
Although ethanol (ethyl alcohol; grain alcohol) has some harmful effects on humans, especially if taken in excess, it is relatively safe to drink in beer, wine, and other alcoholic drinks. 
By contrast, methanol is highly toxic. 
Anyone who accidentally or intentionally consumes methanol is likely to experience serious health effects, including death. 
By adding a small amount of DB (denatonium benzoate pure) to methanol, consumers are discouraged—and usually prevented—from drinking the substance.

DB (denatonium benzoate pure) has many other applications. 
For example, DB (denatonium benzoate pure) can be used in a dilute solution to brush on the fingernails of people who are compulsive fingernail-biters. 
Some parents use a similar solution on the thumbs of children who suck their thumbs more than they should. 

DB (denatonium benzoate pure) is also used as an animal repellent. 
Products containing DB (denatonium benzoate pure) can be sprayed on trees, brushes, crops, and other material to prevent deer from grazing on those products. 
One of the DB (denatonium benzoate pure)'s first applications was as a treatment on pig's tails to prevent pigs from biting each other. 
The coatings on electric cables are sometimes impregnated with a DB (denatonium benzoate pure) solution to discourage rats from chewing on them.

DB (denatonium benzoate pure) Cas 3734-33-6 is used as aversive agent to prevent people from eating other toxic but tasteless substance.
DB (denatonium benzoate pure) is one of the most bitter substances known. 
Just a few parts per million will make a product so bitter that children and pets will not be able to swallow it. 
DB (denatonium benzoate pure) makes sweet but highly toxic products such as antifreeze and detergents taste foul.

By the addition of a denaturant, ethyl alcohol is made non-consumable (bad-tasting/offensive odor)

Aim of the denaturation is to escape the excise duty on drinkable alcohol, and therefore to make alcohol available at a reduced rate for industrial applications, such as the usage in cosmetics and technical applications.


Some of the other applications in which DB (denatonium benzoate pure) has been used include the following:

-In liquid laundry detergents;
-In fabric conditioners;
-In toilet cleaners;
-In disinfectants;
-In household antiseptics;
-In kitchen, bathroom, and floor cleaners;
-In paint products and paint brush cleaners;
-In personal care products, including bath foam, soaps, perfume and after shave lotions, nail polish remover, shampoo, and shower gel;
-In pesticides, such as insecticides, rodenticides, slug bait, and ant bait;
-In herbicides; and
-In a wide variety of automotive care products, such as antifreezes, coolants, and car cleaning materials.

In all of these cases, the purpose of adding DB (denatonium benzoate pure) is to change the taste of the product just enough to prevent someone, especially children, from eating a substance that could cause them harm.

Despite its bitter taste, DB (denatonium benzoate pure) appears to pose little or no hazard to human health. 
Exposure to the DB (denatonium benzoate pure) may cause respiratory discomfort, but only people working with the substance directly are likely to encounter this problem.


DESCRIPTION

Denatonium, usually available as DB (denatonium benzoate pure) and as denatonium saccharide, is the most bitter chemical compound known, with bitterness thresholds of 0.05 ppm for the benzoate and 0.01 ppm for the saccharide.
DB (denatonium benzoate pure) was discovered in 1958 during research on local anesthetics by MacFarlan Smith of Edinburgh, Scotland.

Dilutions of as little as 10 ppm are unbearably bitter to most humans. 
Denatonium salts, like DB (denatonium benzoate pure), are usually colorless and odorless solids but are often traded as solutions. 
They are used as aversive agents (bitterants) to prevent inappropriate ingestion. 

Denatonium is used in denatured alcohol, antifreeze, preventive nail biting preparations, respirator mask fit-testing, animal repellents, liquid soaps, shampoos, and Nintendo Switch game cards to prevent accidental swallowing or choking by children. 
DB (denatonium benzoate pure) is not known to pose any long-term health risks.

The name denatonium reflects the substance's primary use as a denaturant and its chemical nature as a cation, hence the New Latin suffix -onium.

DB (denatonium benzoate pure) is generally regarded as having the most bitter taste of any compound known to science. 
Although DB (denatonium benzoate pure) has a powerful taste, DB (denatonium benzoate pure) is colorless and odorless. 

The taste of DB (denatonium benzoate pure) is so strong, however, that most people cannot tolerate a concentration of more than 30 parts per million of DB (denatonium benzoate pure).
Solutions of DB (denatonium benzoate pure) in alcohol or water are very stable and retain their bitter taste for many years. 
Exposure to light does not lessen the bitter taste of DB (denatonium benzoate pure).

DB (denatonium benzoate pure) compound was discovered in 1958 by a scientist named W. Barnes, who was working for the chemical firm of T. &H. Smith, in Edinburgh, Scotland. 
Barnes was interested in developing a new anesthetic, more powerful than those already available to physicians. 
He decided to focus his research on lidocaine, a very popular anesthetic, and compounds chemically related to it. 

In one line of his experiments, Barnes added a single benzoyl group (benzoic acid with a hydrogen removed: C6H5COO−) to a nitrogen atom in lidocaine. 
The resulting compound was DB (denatonium benzoate pure). 
Although DB (denatonium benzoate pure) had little effectiveness as an anesthetic, Barnes noted that DB (denatonium benzoate pure) had a peculiar odor and taste. 

The claim that DB (denatonium benzoate pure) is the most bitter tasting chemical known is based not on scientific tests but on human taste tests alone. 
No automated test exists for determining the bitterness of a substance.

DB (denatonium benzoate pure) is one of the most bitter substances known. 
Just a few parts per million will make a product so bitter that children and pets will not be able to swallow it. 
DB (denatonium benzoate pure) makes sweet but highly toxic products such as antifreeze and detergents taste foul.

By the addition of a denaturant, ethyl alcohol is made non-consumable (bad-tasting/offensive odor)

Aim of the denaturation is to escape the excise duty on drinkable alcohol, and therefore to make alcohol available at a reduced rate for industrial applications, such as the usage in cosmetics and technical applications.

PROPERTIES

Formula: C21H29N2O.C7H5O2
Formula Weight: 446.59
Form: Powder
Melting point: 164-169°C
Storage & Sensitivity: Ambient temperatures.
Solubility: Soluble in isopropyl alcohol, methanol. 
            Slightly soluble in acetone. 
            Insoluble in ether.


SYNONYMS

N, N-Diethyl-N-[(2,6-dimethylphenylcarbamoyl) methyl] benzylammonium benzoate, 
Benzyldiethyl (2,6-xylylcarbamoylmethyl) ammonium benzoate, 
THS 839 
Benzenemethanamium
Benzyldiethyl(2,6-xylyl­carbamoyl­methyl)­ammonium benzoate
Denatonium benzoate anhydrous; N-(2-((2,6-Dimethylphenyl)amino)-2-oxoethyl)-N,N-diethylbenzenemethanaminium benzoate; 
Anispray; Aversion; Benzenemethanaminium, N-(2-((2,6-dimethylphenyl)amino)-2-oxoethyl)-N,N-diethyl-, benzoate; 
Benzoate de denatonium [INN-French]; Benzoato de denatonio [INN-Spanish]; 
Benzyldiethyl((2,6-xylylcarbamoyl)methyl)ammonium benzoate; Bitrex; 
Denatonii benzoas [INN-Latin]; Denatonium; Gori; Lidocaine benzyl benzoate; 
THS-839; WIN 16568; Ammonium, benzyldiethyl((2,6-xylylcarbamoyl)methyl)-, benzoate; 
((2,6-Xylylcarbamoyl)methyl)diethyl benzyl ammonium benzoate; [ChemIDplus] Lignocaine benzyl benzoate
DENATONIUM BENZOATE
3734-33-6
Bitrex
Lidocaine benzyl benzoate
Denatonium (benzoate)
Aversion
THS-839
Denatonium benzoate anhydrous
Benzoato de denatonio
Benzoate de denatonium
UNII-M5BA6GAF1O
WIN 16568
MFCD00031578
M5BA6GAF1O
Denatonium benzoate granules
3734-33-6 (benzoate)
NSC 157658
C28H34N2O3
NSC-157658
Benzyldiethyl((2,6-xylylcarbamoyl)methyl)ammonium benzoate
Benzyldiethyl[(2,6-xylylcarbamoyl)methyl]ammonium benzoate
NCGC00017043-02
Anispray
CAS-3734-33-6
Gori
benzyl-[2-(2,6-dimethylanilino)-2-oxoethyl]-diethylazanium;benzoate
DSSTox_CID_14376

  • Share !
E-NEWSLETTER