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Dehydroacetic Acid (DHA) is a crystalline compound widely used as a preservative and fungicide in personal care, cosmetic, and pharmaceutical formulations.
Dehydroacetic Acid (DHA) is valued for its broad-spectrum antimicrobial properties, providing effective preservation against fungi, bacteria, and yeast without affecting the formulation’s pH significantly.
Dehydroacetic Acid (DHA) is particularly popular in formulations aiming for "natural" or "clean" labels, due to its safe profile and mild effect on skin and hair.
CAS Number: 520-45-6
EC Number: 208-293-9
Molecular Formula: C8H8O4
Molecular Weight: 168.15 g/mol
Synonyms: Dehydroacetic Acid, DHA, Dihydroacetic Acid, DHA Preservative, Acetic Acid Dehydro, 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione, 3-Acetyl-6-methyl-2,4-pyrone, 6-Methyl-3-acetyl-2-pyrone, Acetic Acid Derivative DHA, Fungicide DHA, Cosmetic Preservative DHA, Dehydroacetic Acid Preservative, Pyrone DHA, Organic Preservative DHA, 3-Acetyl-6-methyl-4H-pyran-4-one, EINECS 208-293-9, Skin-safe Preservative DHA, Dicarboxylic Acid Derivative, Antimicrobial Agent DHA, Cosmetic Grade DHA, C8H8O4, Preservative E265
APPLICATIONS
Dehydroacetic Acid (DHA) is widely used in lotions, creams, and other skincare products as a preservative, protecting formulations from microbial contamination and extending shelf life.
Dehydroacetic Acid (DHA) is applied in shampoos, conditioners, and other hair care products, where it prevents the growth of bacteria and fungi, ensuring product safety and longevity.
Dehydroacetic Acid (DHA) is commonly included in face cleansers and makeup removers, where it provides broad-spectrum antimicrobial protection while remaining mild on the skin.
Dehydroacetic Acid (DHA) is essential in natural and organic cosmetic formulations, where it acts as a preservative without impacting pH, making it ideal for "clean label" products.
Dehydroacetic Acid (DHA) is incorporated into serums and eye creams, where it provides preservation benefits, preventing spoilage of sensitive ingredients like peptides and antioxidants.
Dehydroacetic Acid (DHA) is used in sunscreens and after-sun lotions, offering microbial protection for formulations exposed to warm and humid environments.
Dehydroacetic Acid (DHA) is included in dental care products, such as mouthwashes and toothpaste, where it prevents microbial contamination and extends product stability.
Dehydroacetic Acid (DHA) is found in deodorants and antiperspirants, providing safe and effective preservation, especially in formulations with water content.
Dehydroacetic Acid (DHA) is applied in hand sanitizers, where it complements other ingredients by offering additional preservation against bacterial and fungal growth.
Dehydroacetic Acid (DHA) is utilized in wet wipes and other disposable personal care items, ensuring they remain free from microbial contamination during storage and use.
Dehydroacetic Acid (DHA) is used in body and face mists, where it provides stability by preventing microbial growth in water-based formulations.
Dehydroacetic Acid (DHA) is incorporated into baby care products, such as lotions and cleansers, where its mild, safe profile makes it suitable for delicate skin.
Dehydroacetic Acid (DHA) is applied in bath and shower gels, providing reliable preservation for products exposed to moisture and humidity.
Dehydroacetic Acid (DHA) is used in facial masks, especially sheet masks and other products with high water content, where it prevents spoilage and contamination.
Dehydroacetic Acid (DHA) is a key ingredient in cosmetics like foundations, concealers, and mascaras, ensuring product safety and stability throughout their shelf life.
Dehydroacetic Acid (DHA) is an ingredient in liquid and cream-based makeup formulations, where it preserves both the consistency and safety of the product.
Dehydroacetic Acid (DHA) is used in soaps and body washes, where it protects against microbial growth and maintains the product’s integrity.
Dehydroacetic Acid (DHA) is included in pet care products, where it prevents spoilage and contamination in shampoos and grooming sprays.
DESCRIPTION
Dehydroacetic Acid (DHA) is a synthetic organic compound known for its effective antimicrobial and preservative properties, used across personal care, pharmaceutical, and food products.
Dehydroacetic Acid (DHA) is characterized by its crystalline structure and mild odor, making it compatible with a range of personal care formulations.
Due to its broad-spectrum effectiveness, Dehydroacetic Acid (DHA) is often chosen for water-based formulations that are prone to contamination by bacteria, fungi, and yeast.
Dehydroacetic Acid (DHA) has a stable nature that ensures product safety and longevity, even in formulations exposed to different environmental conditions.
The mildness of Dehydroacetic Acid (DHA) makes it a preferred preservative in products for sensitive skin, including baby care and "natural" cosmetics.
Dehydroacetic Acid (DHA) is a biodegradable compound, making it an environmentally friendly choice in products with sustainable and clean-label claims.
PROPERTIES
Chemical Formula: C8H8O4
Molecular Weight: 168.15 g/mol
Common Name: Dehydroacetic Acid (DHA)
Appearance: White crystalline powder or flakes
Density: Approx. 1.38 g/cm³
Boiling Point: Decomposes before boiling
Melting Point: 108–110°C
Solubility: Soluble in alcohol, slightly soluble in water
Flash Point: 105°C
Reactivity: Stable under normal conditions; avoid strong oxidizing agents
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store in a cool, dry place away from direct sunlight and moisture
Vapor Pressure: Low
FIRST AID
Inhalation:
If Dehydroacetic Acid (DHA) dust or vapors are inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.
Skin Contact:
Wash the affected area with soap and water.
If skin irritation or rash develops, seek medical attention.
Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.
Ingestion:
If Dehydroacetic Acid (DHA) is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.
Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.
HANDLING AND STORAGE
Handling:
Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and dust masks when handling large quantities of Dehydroacetic Acid (DHA).
Use in a well-ventilated area to avoid inhalation of dust or vapors.
Ventilation:
Ensure adequate ventilation when handling Dehydroacetic Acid (DHA) to control airborne concentrations below occupational exposure limits.
Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Dehydroacetic Acid (DHA).
Wash hands thoroughly after handling.
Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Sweep up spills carefully to avoid dust generation and dispose of according to local regulations.
Storage:
Store Dehydroacetic Acid (DHA) in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers.
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and moisture.
Handling Cautions:
Avoid inhalation of dust and direct contact with skin and eyes.
Use explosion-proof equipment in areas where dust particles may be present.
