DEQUEST 2010 LC

DEQUEST 2010 LC= ETIDRONIC ACID
CAS Number: 2809-21-4
EC Number: 220-552-8
Molecular Weight: 206.02800 g/mol
Formula: C2H8O7P2
IUPAC Name: (1-hydroxy-1-phosphonoethyl)phosphonic acid 

DESCRIPTION:

DEQUEST 2010 LC is a bisphosphonate used in detergents, water treatment, cosmetics and pharmaceutical treatment.
DEQUEST 2010 LC is a chelating agent and may be added to bind to or counter the effects of substances such as arsenic, iron, or other metal ions that can occur in the presence of some soaps. 
DEQUEST 2010 LC also acts to retard oxidation of fatty acids. 
For clarification, a chelator, or chelating agent is a binding component added to many cosmetics, beauty products.
Etidronic Acid is as a member of the family of drugs known as bisphosphonates, etidronate differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. 
DEQUEST 2010 LC adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. 
Etidronate may also directly stimulate bone formation by osteoblasts. 
Etidronic acid is a 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. 
Etidronic acid inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces. 
Etidronic acid has a role as a bone density conservation agent, a chelator and an antineoplastic agent. 
Etidronic acid is a conjugate acid of an etidronic acid(2-).
Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid]. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. 
Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]. Etidronic acid was granted FDA approval on 1 September 1977.

CAS Number: 2809-21-4
EC Number: 220-552-8
Molecular Weight: 206.02800 g/mol
Formula: C2H8O7P2
IUPAC Name: (1-hydroxy-1-phosphonoethyl)phosphonic acid 

PHYSICAL AND CHEMICAL PROPERTIES of DEQUEST 2010 LC:

Flash point: Non flammable aqueous solution
Specific gravity: 1.45 @ 20 C
pH: <2.0 Conditions 10 g/l @ 25 C
Freezing point -25 C
Water solubility: completely miscible
Viscosity : 46.0 mPa.s @ 20 C
20.2 mPa.s @ 40 C
10.3 mPa.s @ 60 C
Physical state : liquid [liquid]
 Color : White to yellowish.
Odor : Characteristic.
Odor threshold : Not available.
pH : < 2,0 [Conc. (% w/w): 10 g/l ] @ 25 °C (77.00 °F)
Melting point : .25 °C (13.00. °F) 
Flammability (solid, gas) : Non.flammable.
Relative density : 1,45 @ 20 °C (68.00 °F)
Solubility : Miscible in water.
Octanol/water partition coefficient : .3,5 @ 20 °C (68.00 °F)
Kinematic viscosity: 46 mm2/s @ 20 °C (68.00 °F)
5,0 mm2/s @ 90 °C (194.00 °F)
10,3 mm2/s @ 60 °C (140.00 °F)
20,2 mm2/s @ 40 °C (104.00 °F)
PSA：154.91000
XLogP3：-3.7
Appearance：Liquid
Density：1.45 (60% aq.)
Melting Point：155 °C (decomp)
Boiling Point：578.8ºC at 760 mmHg
Flash Point：303.8ºC
Refractive Index：1.586
Water Solubility：Soluble in water.
Vapor Pressure：8.34E-16mmHg at 25°C
Toxicity：LD50 oral in mouse: 1800mg/kg
Molecular Weight:    206.03    
XLogP3-AA:    -3.7    
Hydrogen Bond Donor Count:    5    
Hydrogen Bond Acceptor Count:    7    
Rotatable Bond Count:    2    
Exact Mass:    205.97452659    
Monoisotopic Mass:    205.97452659    
Topological Polar Surface Area:    135 Ų    
Heavy Atom Count:    11    
Formal Charge:    0    
Complexity:    211    
Isotope Atom Count:    0    
Defined Atom Stereocenter Count:    0    
Undefined Atom Stereocenter Count:    0    
Defined Bond Stereocenter Count:    0    
Undefined Bond Stereocenter Count:    0    
Covalently-Bonded Unit Count:    1    
Compound Is Canonicalized: Yes    

CAS Number: 2809-21-4
EC Number: 220-552-8
Molecular Weight: 206.02800 g/mol
Formula: C2H8O7P2
IUPAC Name: (1-hydroxy-1-phosphonoethyl)phosphonic acid 

Uses and Manufacturing of DEQUEST 2010 LC:
DEQUEST 2010 LC is an organic phosphonic acid scale and corrosion inhibitor. 
DEQUEST 2010 LC can form stable complexes with various metal ions such as iron, copper, and zinc, and can dissolve oxides on the metal surface. 
DEQUEST 2010 LC can still play a good role in corrosion and scale inhibition at 250 ℃, DEQUEST 2010 LC is still stable at high pH, not easy to hydrolyze, and DEQUEST 2010 LC is not easy to decompose under general light and heat conditions. 
DEQUEST 2010 LC has better acid and alkali resistance and chlorine oxidation resistance than other organic phosphonic acids (salts). 
DEQUEST 2010 LC can form a six-ring chelate with metal ions in water, especially calcium ions, so it has good scale inhibition effect and obvious solubility limit effect.
When used in combination with other water treatment agents, DEQUEST 2010 LC shows an ideal synergistic effect . 
DEQUEST 2010 LC solids are high-purity products, suitable for severe winter areas; especially suitable for cleaning agents and daily chemical additives in the electronics industry.
Industry Uses:
•    Corrosion inhibitors and anti-scaling agents
•    Finishing agents
•    Intermediates
•    Plating agents and surface treating agents
•    Processing aids, not otherwise listed
•    Solvents (for cleaning and degreasing)
•    Surface active agents
•    used in detergent manufacture

Consumer Uses    :
•    Automotive care products
•    Building/construction materials - wood and engineered wood products
•    Cleaning and furnishing care products
•    Fabric, textile, and leather products not covered elsewhere
•    Lubricants and greases
•    Metal products not covered elsewhere
•    Water treatment products

CAS Number: 2809-21-4
EC Number: 220-552-8
Molecular Weight: 206.02800 g/mol
Formula: C2H8O7P2
IUPAC Name: (1-hydroxy-1-phosphonoethyl)phosphonic acid 

SAFETY INFORMATION ABOUT DEQUEST 2010 LC:

FIRST AID MEASURES
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. 
Get medical aid. 
Gently lift eyelids and flush continuously with water.
Skin:
Get medical aid. 
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse. 
Flush skin with plenty of soap and water.
Ingestion:
Do NOT induce vomiting. 
If victim is conscious and alert, give 2-4 cupfuls of milk or water. 
Never give anything by mouth to an unconscious person. 
Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. 
If not breathing, give artificial respiration. 
If breathing is difficult, give oxygen. 
Get medical aid. 
Do NOT use mouth-to-mouth resuscitation.
FIRE-FIGHTING MEASURES
General Information:
Containers can build up pressure if exposed to heat and/or fire. 
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. 
Vapors may form an explosive mixture with air. 
Vapors can travel to a source of ignition and flash back. 
Will burn if involved in a fire. 
Flammable Liquid.
Can release vapors that form explosive mixtures at temperatures above the flashpoint. 
Use water spray to keep fire-exposed containers cool. 
Containers may explode in the heat of a fire.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. 
For large fires, use water spray, fog, or alcohol-resistant foam. 
Use water spray to cool fire-exposed containers. 
Water may be ineffective. 
Do NOT use straight streams of water.
Fire fighting equipment:
Firefighters, and others exposed, wear self-contained breathing apparatus.
Equipment should be thoroughly decontaminated after use.
ACCIDENTAL RELEASE MEASURES
General Information:
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition. 
Use a spark-proof tool. 
Provide ventilation. 
A vapor suppressing foam may be used to reduce vapors.
Methods for cleaning up:
Contain large spills with dikes and transfer the material to appropriate containers for reclamation or disposal. 
Absorb remaining material or small spills with an inert material and then place in a chemical waste container.
Neutralize washings with soda ash or lime. 
Flush spill area with water.
HANDLING AND STORAGE
Handling
Do not get in eyes, on skin, or on clothing. 
Avoid breathing vapour or mist. 
Keep container closed. 
Use with adequate ventilation. 
Wash thoroughly after handling. 
Emptied containers retain vapour and product residue. 
Observe all recommended safety precautions until container is cleaned, reconditioned or destroyed. The reuse of this material's container for non industrial purposes is prohibited and any reuse must be in consideration of the data provided in this material safety data sheet.
Storage:
Temperature: > 0 C
Suitable materials of construction: glass lining; PVC; polypropylene; glass reinforced plastic; polyethylene
Unsuitable materials of construction: mild steel; carbon steel; aluminum; other metals
General: Freeze sensitive. Keep in a cool, dry, well ventilated place. 
Stable under normal conditions of handling and storage.
EXPOSURE CONTROLS / PERSONAL PROTECTION
No specific occupational exposure limit has been established.
Engineering Controls:
Use explosion-proof ventilation equipment. 
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. 
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Eye protection:
Wear chemical goggles.
Have eye wash facilities immediately available at any location where eye contact can occur.
Hand protection:
Although this product does not present a significant skin concern, minimize skin contamination by following good industrial practice. 
Wearing protective gloves is recommended. 
Consult the glove/clothing manufacturer to determine the appropriate type glove/clothing for a given application.
Body protection:
Although this product does not present a significant skin concern, minimize skin contamination by following good industrial practice. 
Wash thoroughly after handling.
Respiratory protection:
Avoid breathing vapour or mist. 
Use approved respiratory protection equipment when airborne exposure is excessive.
If used, full facepiece replaces the need for face shield and/or chemical goggles.
 Consult the respirator manufacturer to determine the appropriate type of equipment for a given application. 
Observe respirator use limitations specified by the manufacturer.
Ventilation:
Provide natural or mechanical ventilation to minimize exposure. 
If practical, use local mechanical exhaust ventilation at sources of air contamination such as processing equipment.
Components referred to herein may be regulated by specific Canadian provincial legislation. 
Please refer to exposure limits legislated for the province in which the substance will be used

STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, oxidizers. 
Do not expose to extreme temperatures.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, alkali metals, ammonia, hydrazine, peroxides, sodium, acid anhydrides, calcium hypochlorite, chromyl chloride, nitrosyl perchlorate, bromine pentafluoride, perchloric acid, silver nitrate, mercuric nitrate, potassium-tertbutoxide, magnesium perchlorate, acid chlorides, platinum, uranium hexafluoride, silver oxide, iodine heptafluoride, acetyl bromide, disulfuryl difluoride, tetrachlorosilane + water, acetyl chloride, permanganic acid, ruthenium (VIII) oxide, uranyl perchlorate, potassium dioxide.
Attacks many metals.
Corrosive to aluminum and mild steel.
Contact with strong oxidizing agents.
Contact with strong bases.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization:
Will not occur.
DISPOSAL CONSIDERATIONS
US EPA RCRA Status
DEQUEST 2010 LC when discarded is a hazardous waste as that term is defined by the Resource, Conservation and Recovery Act (RCRA),40 CFR 261. 
See disposal considerations below for U.S. EPA disposal requirements. 
Consult regulatory officials for performance standards.
US EPA RCRA
hazardous waste number: D002
Compound/Characteristic: Corrosivity
Disposal considerations:
Deactivation Consult 40 CFR 268.48 for concentration based standards.
Miscellaneous advice:
Local, state, provincial, and national disposal regulations may be more or less stringent. 
Consult your attorney or appropriate regulatory officials for information on such disposal. 
DEQUEST 2010 LC should not be dumped, spilled, rinsed or washed into sewers or public waterways.

CAS Number: 2809-21-4
EC Number: 220-552-8
Molecular Weight: 206.02800 g/mol
Formula: C2H8O7P2
IUPAC Name: (1-hydroxy-1-phosphonoethyl)phosphonic acid 

Synonyms of DEQUEST 2010 LC:
MeSH Entry Terms:
(1-hydroxyethylene)diphosphonic acid

(1-hydroxyethylene)diphosphonic acid, Tetrapotassium Salt

1 Hydroxyethane 1,1 Diphosphonate

1 Hydroxyethylidene 1,1 Bisphosphonate

1,1 hydroxyethylenediphosphonate

1,1-hydroxyethylenediphosphonate

1-Hydroxyethane-1,1-Diphosphonate

1-Hydroxyethylene Diphosphonate, Disodium

1-Hydroxyethylidene-1,1-Bisphosphonate

Dicalcium EHDP

Dicalcium Etidronate

Didronel

Diphosphonate, Disodium 1-Hydroxyethylene

Diphosphonic Acid, Hydroxyethylidene

Disodium 1 Hydroxyethylene Diphosphonate

Disodium 1-Hydroxyethylene Diphosphonate

Disodium Etidronate

EHDP

EHDP, Dicalcium

Ethanehydroxydiphosphonate

Ethanehydroxyphosphate

Etidronate

Etidronate Disodium

Etidronate, Dicalcium

Etidronate, Disodium

Etidronate, Sodium

Etidronate, Tetrapotassium Salt

Etidronic Acid

HEDP

HEDSPA

Hydroxyethanediphosphonate

Hydroxyethylidene Diphosphonic Acid

Phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt

Salt Etidronate, Tetrapotassium

Sodium Etidronate

Tetrapotassium Salt Etidronate

Xidifon

Xidiphon

Xydiphone

Depositor-Supplied Synonyms    
Etidronic acid

2809-21-4

etidronate

HEDP

1-Hydroxyethylidene-1,1-diphosphonic acid

EHDP

Etidronsaeure

Acetodiphosphonic acid

Hydroxyethanediphosphonic acid

Turpinal SL

Oxyethylidenediphosphonic acid

Didronel

Dequest 2015

Dequest Z 010

Acido etidronico

Ferrofos 510

Acide etidronique

1-Hydroxyethane-1,1-diphosphonate

1-Hydroxyethane-1,1-diphosphonic acid

Phosphonic acid, (1-hydroxyethylidene)bis-

Diphosphonate (base)

(1-Hydroxyethane-1,1-diyl)diphosphonic acid

1-Hydroxyethanediphosphonic acid

Dequest 2010

Ethane-1-hydroxy-1,1-diphosphonic acid

(Hydroxyethylidene)diphosphonic acid

Ethane-1-hydroxy-1,1-diphosphonate

(1-Hydroxyethylene)diphosphonic acid

Acide etidronique [INN-French]

Acido etidronico [INN-Spanish]

Acidum etidronicum [INN-Latin]

(1-Hydroxyethylidene)diphosphonic acid

1,1,1-Ethanetriol diphosphonate

1-Hydroxyethylidene-1,1-bisphosphonate

1-Hydroxyethane-1,1-bisphosphonic acid

1-HYDROXY-1,1-DIPHOSPHONOETHANE

(1-Hydroxyethylidene)bis(phosphonic acid)

Acidum etidronicum

(1-Hydroxyethylidene)bisphosphonic acid

(1-hydroxyethane-1,1-diyl)bis(phosphonic acid)

Hydroxyethane-1,1-diphosphonic acid

1000SL

(1-Hydroxyethylidene)diphoshonic acid

UNII-M2F465ROXU

(1-hydroxy-1-phosphonoethyl)phosphonic acid

Phosphonic acid, (1-hydroxyethylidene)di-

MFCD00070585

CHEMBL871

M2F465ROXU

ethane-1-hydroxy-1,1-bisphosphonic acid

CHEBI:4907

2809-21-4 (freeacid)

1-hydroxyethane 1,1-diphosphonic acid

NSC-227995

(1-hydroxyethan-1,1-diyl)bis(phosphonic acid)

(1-Hydroxy-1,1-ethanediyl)bis(phosphonic acid)

Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-

Etidronic acid [USAN:INN:BAN]

RP 61

SMR000038750

1-Hydroxyethylidene-1,1-biphosphonate

HSDB 5898

NCGC00159352-02

EINECS 220-552-8

Phosphonic acid, 1-hydroxy-1,1-ethanediyl ester

NSC 227995

BRN 1789291

Etidronic acid (USAN/INN)

etidronic-acid

C2H8O7P2

(1-hydroxy-1-phosphono-ethyl)phosphonic acid

1-hydroxy ethylidene

Ethane-1-hydroxy-1,1-bisphosphonate

HDEPA

HEDPA

OEDFK

Etidronate (Didronel)

1-HydroxyEthylidene-1,1-DiphosphonicAcid

Prestwick0_000863

Prestwick1_000863

Prestwick2_000863

Prestwick3_000863

DSSTox_CID_3028

EC 220-552-8

DSSTox_RID_76837

DSSTox_GSID_23028

SCHEMBL18607

BSPBio_000905

0-02-00-00171 (Beilstein Handbook Reference)

MLS002207267

MLS002695948

SPBio_002826

BPBio1_000997

GTPL7184

DTXSID6023028

M05BA01

HMS3604E03

HY-B0302

ZINC3830813

Tox21_200417

BBL028139

BDBM50115102

DL-390

Etidronic acid 60% aqueous solution

NSC227995

s1857

STK721995

AKOS005524039

Etidronic acid, 60% aqueous solution

CCG-266618

DB01077

MCULE-3037955142

(1-hydroxy-ethylidene)diphosphonic acid

s12329

NCGC00159352-04

NCGC00159352-05

NCGC00159352-06

NCGC00257971-01

K958

1-hydroxyethane-1,1-diyldiphosphonic acid

CAS-2809-21-4

1-hydroxy ethylidene-1,1-diphosphonic acid

FT-0607934

FT-0668439

H0587

(1-Hydroxy-1-phosphono-ethyl)-phosphonic acid

A23202

C07736

D02373

(1-Hydroxyethylidene)bisphosphonic acid monohydrate

J-504794

Q2758338

1-Hydroxy Ethylidene-1,1-Diphosphonic Acid (Powder)

(1-Hydroxyethane-1,1-diyl)diphosphonic acid monohydrate

1-Hydroxyethylidenediphosphonic acid 60% aqueous solution

1-Hydroxyethane-1,1,-diphosphonic acid 60% aqueous solution