PRODUCTS

DEXPANTHENOL (PANTHENOL)

Dexpanthenol (Panthenol) is a monocarboxylic acid amide that is 3,3-dimethylbutanamide substituted by hydroxy groups at positions 2 and 4 and a 3-hydroxypropyl group at the carbomyl nitrogen.
Dexpanthenol (Panthenol) has a role as a cholinergic drug and a provitamin.
Dexpanthenol (Panthenol) is an amino alcohol and a monocarboxylic acid amide.

CAS Number: 81-13-0
Molecular Formula: C9H19NO4
Molecular Weight: 205.25
EINECS Number: 201-327-3

Synonyms: Dexpanthenol, D-Panthenol, 81-13-0, Dexpanthenol (Panthenol), D-Pantothenyl alcohol, Bepanthen, Ilopan, Bepanthene, Bepantol, Pantol, (+)-Panthenol, Provitamin B, Panthoderm, Thenalton, Motilyn, Panadon, Zentinic, d-Dexpanthenol (Panthenol), Pantothenyl alcohol, Cozyme, D(+)-Panthenol, D-P-A Injection, Pantenyl, Synapan, Urupan, Intrapan, D(+)-Pantothenyl alcohol, D-Panthenol 50, Provitamin B5, Dexpantenol, Pantothenylol, d panthenol, (R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide, (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide, Dexpanthenolum, Penthenol, Varitan, Alcopan-250, Dextro pantothenyl alcohol, Propanolamine, N-pantoyl-, N-Pantoyl-propanolamine, Sinecort, Dexpanthenol (Panthenol), D-, Panthenol (D), Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-, Panthenol, (+)-, N-Pantoyl-3-propanolamine, D-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide, UNII-1O6C93RI7Z, Panthenol (JAN), Prestwick_529, Dexpanthenol (1.20 g/mL), NSC 302962, Ilopan (TN), CORNERGEL, D-(+)-Panthenol, DOLOBENE, 1O6C93RI7Z, CCRIS 3947, HSDB 296, DTXSID3022906, CHEBI:27373, PANTHENOL 50W, EINECS 201-327-3, MFCD00065006, PANTHENOL, (R)-, Dexpantenol [INN-Spanish], ALCOPAN 250, D-(+)-Pantothenyl alcohol, Dexpanthenolum [INN-Latin], BAY 81-2996, BRN 1724947, Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (R)-, Butyramide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, D-(+)-, DTXCID402906, 2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide, (R)-, EC 201-327-3, 2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide, D-(+)-, 4-04-00-01652 (Beilstein Handbook Reference), Dexpanthenol [USAN:USP:INN:BAN], NSC302962, NSC-302962, component of Pantho-F, NCGC00142622-03, PANTHENOL [JAN], d(+)-2,4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethylbutyramide, (R)-2,4-Dihydroxy-N-(3-hydroxy-propyl)-3,3-dimethylbutanamide, Dexpanthenol (INN-Spanish), Dexpanthenolum (INN-Latin), DEXPANTHENOL (MART.), DEXPANTHENOL [MART.], DEXPANTHENOL (USP-RS), DEXPANTHENOL [USP-RS], (R)-2,4-Dihydroxy-3,3-dimethylbutyric 3-hydroxypropylamide, DEXPANTHENOL (EP MONOGRAPH), DEXPANTHENOL [EP MONOGRAPH], (R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide, Dexpanthenol (USAN:USP:INN:BAN), DEXPANTHENOL (USP MONOGRAPH), DEXPANTHENOL [USP MONOGRAPH], pantothenylol alcohol, component of Zentinic, Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (theta)-, (+-)-Pantothenyl alcohol, DEXPANTHENOL [USAN], dexpantenolo, Fancol DL, CAS-81-13-0, NCGC00186658-01, Dexpanthenol (USP), BABYSONS, Panthenol, (+ )-, D-Panthenol 10 microg/mL in Acetonitrile, Prestwick0_000022, Prestwick1_000022, Prestwick2_000022, Prestwick3_000022, Dexpanthenol (USP/INN), DEXPANTHENOL [MI], compnent of ilopan-Choline, DEXPANTHENOL [FCC], DEXPANTHENOL [INN], bmse000445, DEXPANTHENOL [HSDB], D-PANTHENOL [VANDF], DEXPANTHENOL [VANDF], SCHEMBL15861, BSPBio_000083, DEXPANTHENOL [WHO-DD], SPBio_002004, (R)-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide, BPBio1_000093, CHEMBL1200979, SCHEMBL20553090, A11HA30, D03AX03, S01XA12, DEXPANTHENOL [ORANGE BOOK], HMS1568E05, HMS2094E09, HMS2095E05, HMS3712E05, YOZUM WELL BEING HAIR COLOR, (+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide, HY-B1391, D-Panthenol, >=98.0% (NT), Tox21_111563, LMFA08020198, s4695, AKOS015841507, AKOS015901947, D(+)-alpha,gamma-Dihydroxy-N-(3-hydroxypropyl)-beta,beta-dimethylbutyramide, Tox21_111563_1, CCG-213429, CS-8175, DB09357, alpha,gamma-Dihydroxy-N-(3-hydroxypropyl)-beta,beta-dimethylbutyramide, D-(+)-, NCGC00142622-01, NCGC00142622-04, AS-14732, Dexpanthenol, tested according to Ph.Eur., SBI-0206936.P001, D-Panthenol, Vetec(TM) reagent grade, 98%, NS00076665, P0692, C05944, D00193, D70909, EN300-7414583, Q-201048, BRD-K71210479-001-05-5, Q47495755, A6CF1A81-5B98-4C28-A379-EA28FA9DD210, (R)-3-(2,4-Dihydroxy-3,3-dimethylbutyramido)-1-propanol, 2,4-Dihydroxy-N-(3-hydroxy-propyl)-3,3-dimethylbutanamide, Dexpanthenol, European Pharmacopoeia (EP) Reference Standard, (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-butanamide, (R)-()-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide, (R)-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide, (R)-2,4-dihydroxy-3,3-dimethyl-N-(3-hydroxypropyl)-butanamide, (R)-2,4-Dihydroxy-N-(3-hydroxy-propyl)-3,3-dimethyl-butyramide, D-(+)-2,4-Dihydroxy-3,3-dimethyl-N-(3-hydroxypropyl)butyramide, d-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl butyramide, D-Panthenol, >=98% (perchloric acid titration), >=98% (TLC), Dexpanthenol, United States Pharmacopeia (USP) Reference Standard, (D)-(+)-2, 4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide, D(+)-.ALPHA.,.GAMMA.-DIHYDROXY-N-(3-HYDROXYPROPYL)-.BETA.,.BETA.-DIMETHYLBUTYRAMIDE, Dexpanthenol, Pharmaceutical Secondary Standard, Certified Reference Material, 4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-(theta)-butanamid, 4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-d-(+)-butyramid, Alcopan-250, Bepanthen, Bepanthene, Bepantol, Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl.

Dexpanthenol (Panthenol) belongs to a derivative of pantothenic acid (vitamin B5).
Dexpanthenol (Panthenol) can penetrate the skin and mucous membrane to be quickly oxidized to pantothenic acid.
The later one is extremely hygroscopic and binds water effectively.

Dexpanthenol (Panthenol) can be used as a moisturizer.
It is added to pharmaceutical and cosmetic products to relieve itching and improve wound healing.
In ointments, it can be used for the treatment of sunburns, mild burns, minor skin injuries and disorders.

Dexpanthenol (Panthenol) is also immediately applied after major abdominal surgery to minimize the possibility of paralytic ileus.
In addition, it can also be supplemented into the commercial shampoos and hair conditioners to lubricate the hair shaft and give the hair a shiny appearance.
The exact mechanism of action of Dexpanthenol (Panthenol) is still unclear, perhaps through its enhancing effect on acetylcholine.

Dexpanthenol (Panthenol) is the alcohol analog of pantothenic acid (vitamin B5), and is thus a provitamin of B5.
In organisms, it is quickly oxidized to pantothenic acid.
Dexpanthenol (Panthenol) is a viscous transparent liquid at room temperature. Panthenol is used in pharmaceutical and children's products as a moisturizer and to hasten wound healing.

Dexpanthenol (Panthenol) is an alcohol analog of pantothenic acid and an important component of parenterals, local cosmetic preparations and multi-vitamins.
It has as much biological activity as pantothenic acid and is found to be stable in aqueous solution.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Dexpanthenol (Panthenol) is the alcohol analogue and biological precursor of D-pantothenic acid.
These analogues are precursors in the biosynthesis of coenzyme A.
Dexpanthenol (Panthenol) and D-Pantothenic acid are used in a variety of skin protection products.

Dexpanthenol (Panthenol) may have a role in controlling keratinocyte proliferation and differentiation.
Dexpanthenol (Panthenol) may be used for studies of skin protection emulsions from UV irradiation and as a humectant.
Dexpanthenol (Panthenol) is the alcohol corresponding to pantothenic acid, of the vitamin B5 group.

It is used as a food additive, and in skin and hair products as a conditioning agent. Contact dermatitis and urticaria have been reported.
Dexpanthenol (Panthenol) is an alcohol analog of pantothenic acid and an important component of parenterals, local cosmetic preparations and multi-vitamins.
Dexpanthenol (Panthenol) has as much biological activity as pantothenic acid and is found to be stable in aqueous solution.

Therefore, Dexpanthenol (Panthenol) can be used as a moisturizer.
Dexpanthenol (Panthenol) is added to pharmaceutical and cosmetic products to relieve itching and improve wound healing.
In ointments, Dexpanthenol (Panthenol) can be used for the treatment of sunburns, mild burns, minor skin injuries and disorders.

Dexpanthenol (Panthenol) is also immediately applied after major abdominal surgery to minimize the possibility of paralytic ileus.
In addition, Dexpanthenol (Panthenol) can also be supplemented into the commercial shampoos and hair conditioners to lubricate the hair shaft and give the hair a shiny appearance.
The exact mechanism of action of Dexpanthenol (Panthenol) is still unclear, perhaps through its enhancing eect on acetylcholine.

A moisturiser and humectant (which means it soaks up water and retains it) - Dexpanthenol (Panthenol) calms and repairs dry, cracked, irritated skin.
Often found in creams, ointments and other topical products, Dexpanthenol (Panthenol) can be a hydrating lifeline to those who are plagued by dry, tight skin.
Dexpanthenol (Panthenol)’s powers don’t stop at healing and hydrating, dexpanthenol can strengthen skin’s natural barrier, making it less susceptible to dryness and its associated problems.

Below we explore what is Dexpanthenol (Panthenol) and take a closer look at dexpanthenol cream and its uses.
Dexpanthenol (Panthenol) is a derivative of pantothenic acid, a B complex vitamin.
Dexpanthenol (Panthenol) is usually applied topically in cream or lotion form to improve hydration and reduce water loss while helping to keep the skin soft and supple.

Dexpanthenol (Panthenol) has good penetration qualities which means it is capable of sinking into the skin, enabling it to get to the heart of the problem rather than simply sitting on the skin’s surface.
Dexpanthenol (Panthenol) acts on the gastrointestinal tract and increases lower intestinal motility.
Dexpanthenol (Panthenol) is also applied topically to the skin to relieve itching and to promote healing.

Dexpanthenol (Panthenol) is an alcohol form of the B5 vitamin pantothenic acid.
Dexpanthenol (Panthenol) easily penetrates the skin retaining water and is a humectant, emollient and moisturizer.
Dexpanthenol (Panthenol) mitigates signs of inammation and stimulates epithelization.

Dexpanthenol (Panthenol) comes in two enantiomers, D and L.
Only Dexpanthenol (Panthenol) is biologically active, however both forms have moisturizing properties.
Because of the ability to attract and hold moisture panthenol is used in skincare products as a humectant.

Dexpanthenol (Panthenol) also has a role as provitamin (called pro-vitamin B5) and is used as a vitamin supplement in complex ( M.V.I. ADULT injection, Hospira Worldwide, Inc.) and alone, and as a cholinergic drug.
Dexpanthenol (Panthenol) is a highly viscous transparent liquid at room temperature, but salts of pantothenic acid (sodium pantothenate) are powders (typically white).
Dexpanthenol (Panthenol) is soluble in water, alcohol, propylene glycol, ether and chloroform, and slightly soluble in glycerin.

Dexpanthenol (Panthenol) mixes readily with many dierent types of ingredients, making it a versatile ingredient to be used in formulas because Dexpanthenol improves skin’s barrier function and maintains the proliferation of broblasts.
In organisms Dexpanthenol (Panthenol) is quickly oxidized to pantothenate (pantothenic acid).
Deciency of Vitamin B5 results in many dermatological disorder.

Due to the fact that only Dexpanthenol (Panthenol) is converted to Vitamin B5 and not L-Panthenol, the racemic mixture of D- and L- panthenol (DL-panthenol) has only half of the physiological activity of the D-Panthenol.
These include stimulation of epithelisation, wound healing eect and anti-in ammatory eect.
Dexpanthenol (Panthenol) is FDA approved for cosmetic use and comes either in D form, or as a racemic mixture.

Dexpanthenol (Panthenol) is also in the FDA list of over-the-counter drug products that are not generally recognized as safe and eective or are misbranded: as "Insect Bite and Sting Drug Products" and "Poison Ivy, Poison Oak, and Poison Sumac Drug Products".
Dexpanthenol (Panthenol) is a medication used as a moisturizer to treat or prevent dry, rough, aky, itchy skin and minor skin irritations (e.g., diaper rash, burns from radiation therapy)

Dexpanthenol (Panthenol) is generally well tolerated. In rare cases, skin irritation and contact allergies have been reported.
Dexpanthenol (Panthenol), also known as Panthenol or Pro-Vitamin B5, is the alcohol form of pantothenic acid (Vitamin B5).
It is a water-soluble compound commonly used in skincare, hair care products, and pharmaceutical applications for its moisturizing and healing properties.

Dexpanthenol (Panthenol) is an odourless, slightly bitter, highly viscous, transparent, and colourless liquid at room temperature, but salts of pantothenic acid (for example sodium pantothenate) are powders that are typically white.
It is easily soluble in water and alcohol, moderately soluble in diethyl ether, soluble in chloroform (1:100), in propylene glycol, and slightly soluble in glycerin.

Dexpanthenol (Panthenol) is the stable biologically active form of pantothenic acid, also known as vitamin B5.
It can be supplied as a racemic mixture of both dextrorotary form (dexpanthanol) and the levorotatory form (levopanthenol) meaning that the molecule comes in 2 forms that are mirror images of each other.
Only the dexpanthenol is biologically active so it is important to look for skincare products calling out D-Panthenol or Dexpanthenol (Panthenol) otherwise the panthenol in the product is likely a racemic mixture with half being the non-biologically active form levopanthenol.

In skincare, Dexpanthenol (Panthenol) is recognized for its ability to attract and hold moisture as well as soothe the skin.
It's often used in a variety of skincare products, from creams and lotions to serums and masks.
Dexpanthenol (Panthenol) performs on the skin by attracting water to the upper topical layer of the skin and holding it there, helping to improve skin hydration and thereby improving the appearance.

It also has a soothing effect, which can help calm irritated skin.
Additionally, when used on a consistent basis, panthenol can improve skin texture and elasticity.
While both forms of panthenol can hydrate the skin, Dexpanthenol (Panthenol) works by enhancing epidermal differentiation and facilitating wound healing which overall aids in reinforcing the skin barrier.

Dexpanthenol (Panthenol), also known as provitamin B5, is an essential ingredient for the proper functioning of the skin.
Thanks to fine particles, it easily penetrates deep into the skin, as well as into the hair fibers and the nail plate.
It strengthens and rebuilds their structure.

Due to its excellent moisturizing properties, Dexpanthenol (Panthenol) is readily used as an ingredient in preparations to soothe irritation and sunburn.
Dexpanthenol (Panthenol) is an alcohol form of the B5 vitamin pantothenic acid.
It easily penetrates the skin retaining water and is a humectant, emollient and moisturizer.

Dexpanthenol (Panthenol) mitigates signs of inflammation and stimulates epithelization.
Dexpanthenol (Panthenol) comes in two enantiomers, D and L. Only D-panthenol (dexpanthenol) is biologically active, however both forms have moisturizing properties.
Because of the ability to attract and hold moisture panthenol is used in skincare products as a humectant.

It also has a role as provitamin (called pro-vitamin B5) and is used as a vitamin supplement in complex ( M.V.I. ADULT injection, Hospira Worldwide, Inc.) and alone, and as a cholinergic drug.
Dexpanthenol (Panthenol) is a highly viscous transparent liquid at room temperature, but salts of pantothenic acid (sodium pantothenate) are powders (typically white).
It is soluble in water, alcohol, propylene glycol, ether and chloroform, and slightly soluble in glycerin.

Dexpanthenol (Panthenol) mixes readily with many different types of ingredients, making it a versatile ingredient to be used in formulas because it improves skin’s barrier function and maintains the proliferation of fibroblasts.
In organisms it is quickly oxidized to pantothenate (pantothenic acid).
Defficiency of Vitamin B5 results in many dermatological disorder.

Due to the fact that only D-Panthenol is converted to Vitamin B5 and not L-Panthenol, the racemic mixture of D- and L- panthenol (DL-panthenol) has only half of the physiological activity of the D-Panthenol.
Dexpanthenol (Panthenol) is the biologically-active alcohol of pantothenic acid, which leads to an elevation in the amount of coenzyme A in the cell.
Dexpanthenol (Panthenol) is a colorless viscous liquid or a colorless transparent liquid with a slight peculiar smell.

Easily soluble in water, ethanol, methanol and propylene glycol.
Dexpanthenol (Panthenol) is also known as original vitamin B5.
It is widely used in medicine, food, cosmetics and liquid preparations.

Dexpanthenol (Panthenol) can be converted into pantothenic acid when entering the human body, and then synthesize coenzyme A, promote the metabolism of human protein, fat and carbohydrates, protect skin and mucous membranes, improve hair luster, and prevent the occurrence of diseases.
Dexpanthenol (Panthenol) can prevent small wrinkles, inflammation, sun exposure, erosion, prevent hair loss, promote hair growth, keep hair moist, reduce split ends, prevent brittleness and breakage, and protect, repair and care for hair.

Melting point: 64～69℃
alpha: 30.5 º (c=5, H2O on anh. sub)
Boiling point: 118-120 °C (2.7 mmHg)
Density: 1.20 g/mL at 20 °C (lit.)
vapor pressure: 0Pa at 25℃
refractive index: 1.495-1.502
Flash point: 118-120°C/0.02m
storage temp.: 2-8°C
solubility: DMSO (Sparingly), Methanol (Slightly), Water (Sparingly)
pka: 13.03±0.20(Predicted)
form: Viscous Liquid or Semi Solid
color: Clear colorless to slightly yellow
PH: pH (100g/l,25℃) : 8.5～10.5
optical activity: [α]20/D +30±1°, c = 5% in H2O
Water Solubility: soluble
Sensitive: Hygroscopic
Merck: 14,2947
BRN: 1724947
InChIKey: SNPLKNRPJHDVJA-ZETCQYMHSA-N
LogP: -1.06 at 22℃

Dexpanthenol (Panthenol) has been suggested for use in intestinal atony or distension, postoperative retention of flatus and feces, prophylaxis and treatment of paralytic ileus after abdominal surgery or traumatic injuries, equine colic (not due to mechanical obstruction) and any other condition when there is an impairment of smooth muscle function.
Controlled studies are lacking with regard to proving the efficacy of the drug for any of these indications.
Purify Dexpanthenol (Panthenol) by distillation in vacuo.

It is a slightly hygroscopic viscous oil and is soluble in H2O and organic solvents.
Dexpanthenol (Panthenol) is hydrolysed by alkali and strong acid.
Dexpanthenol (Panthenol)is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium.

Dexpanthenol (Panthenol) is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium.
Due to Dexpanthenol (Panthenol)'s good penetration and high local concentrations, dexpanthanol is used in many topical products, such as ointments and lotions for treatment of dermatological conditions to relieve itching or promote healing.

Dermatological eects of the topical use of Dexpanthenol (Panthenol) include increased broblast proliferation and accelerated re-epithelialization in wound healing.
Furthermore, Dexpanthenol (Panthenol) acts as a topical protectant, moisturizer, and has demonstrated anti-inammatory properties.
Dexpanthenol (Panthenol) is also available as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol) as Panthenol.

While pantothenic acid is optically active, only the dextrorotatory form Dexpanthenol (Panthenol) is biologically active.
Dexpanthenol (Panthenol) is soluble in water and alcohol, although insoluble in fats and oil based substances.
With the appropriate vehicle, Dexpanthenol (Panthenol) is easily penetrated into the skin.

Rate of penetration and absorption is reduced when Dexpanthenol (Panthenol) is administered as an oil/water formula.
Dexpanthenol (Panthenol) is the alcohol analog of pantothenic acid (vitamin B5), and is thus a provitamin of B5.
In organisms, Dexpanthenol (Panthenol) is quickly oxidized to pantothenic acid.

Dexpanthenol (Panthenol) is a viscous transparent liquid at room temperature.
Dexpanthenol (Panthenol) is used in pharmaceutical and cosmetic products as a moisturizer and to improve wound healing.
An alcoholic analogue of D-pantothenic acid and cholinergic agent.

Dexpanthenol (Panthenol) acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine.
Although the exact mechanism of the actions of Dexpanthenol (Panthenol) is unclear, it may enhance the eect of acetylcholine.
Dexpanthenol (Panthenol) is an organic compound having the chemical formula C9H19NO4.

Dexpanthenol (Panthenol) appears as a highly viscous, colorless liquid.
The density of this liquid is 1.2 g/cm3. The melting point of this compound can range from 66-69 degrees Celsius, and the boiling point ranges from 118 to 120 degrees Celsius.
Dexpanthenol (Panthenol) is an alcohol analog of pantothenic acid.

Therefore, we can name it a provitamin of B5.
In some organisms, panthenol quickly undergoes oxidation to form pantothenic acid.
The major uses of this compound are in the manufacturing of pharmaceutical and cosmetic products as a moisturizer and to improve wound healing.

Dexpanthenol (Panthenol) is often used in creams, lotions, and ointments due to its ability to hydrate the skin, improve barrier function, and promote the healing of wounds, burns, and minor skin irritations.
It is also known for soothing and reducing inflammation in skin conditions like eczema and psoriasis.
In shampoos, conditioners, and other hair products, Dexpanthenol (Panthenol) helps to retain moisture in the hair, improving its texture, shine, and overall health.

It is also used to prevent hair damage caused by styling and environmental factors.
Dexpanthenol (Panthenol) aids in tissue repair and can speed up the healing process for cuts, abrasions, and sunburns by enhancing cell proliferation and regenerating damaged skin.
Dexpanthenol (Panthenol) is included in many cosmetic formulations for its ability to improve skin appearance, texture, and moisture retention.

Dexpanthenol (Panthenol) is the dextrorotatory (D) isomer of panthenol, and it is typically converted into pantothenic acid in the body, which is essential for the synthesis of coenzyme A (CoA) and involved in metabolic processes.
Dexpanthenol (Panthenol) can also be found in dietary supplements that support energy metabolism and skin health, as Vitamin B5 is essential for overall health.

Uses Of Dexpanthenol (Panthenol):
Dexpanthenol (Panthenol) may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques as well as partial least-squares multivariate calibration.
Dexpanthenol (Panthenol) is an analogue of pantothenic acid (P190300), a member of the B complex vitamins.
Dexpanthenol (Panthenol) is the biologically active enantiomer of Panthenol.

In pharmaceuticals, cosmetics, and personal-care products, Dexpanthenol (Panthenol) is a moisturizer and humectant, used in ointments, lotions, shampoos, nasal sprays, eye drops, lozenges, and cleaning solutions for contact lenses.
In ointments it is used for the treatment of sunburns, mild burns, minor skin injuries, and skin disorders (in concentrations of up to 2–5%).
Dexpanthenol (Panthenol) improves hydration, reduces itching and inflammation of the skin, improves skin elasticity, and accelerates epidermal wounds' rate of healing.

For this purpose, it is sometimes combined with allantoin.
Dexpanthenol (Panthenol) binds to the hair shaft readily, due to which it is a common component of commercial shampoos and hair conditioners (in concentrations of 0.1–1%).
It coats the hair and seals its surface,[citation needed] lubricating the hair shaft and giving it a shiny appearance.

Dexpanthenol (Panthenol) is sometimes used as an ingredient in tattoo aftercare products, with one study finding it can assist in wound care and tattoo preservation.
Dexpanthenol (Panthenol) readily penetrates into the skin and mucous membranes (including the intestinal mucosa), where it is quickly oxidized to pantothenic acid.
Dexpanthenol (Panthenol) is extremely hygroscopic.

It is also used in the biosynthesis of coenzyme A, which plays a role in a wide range of enzymatic reactions and in cell growth.
Dexpanthenol (Panthenol) readily penetrates into the skin and mucous membranes (including the intestinal mucosa), where it is quickly oxidized to pantothenic acid.
Dexpanthenol (Panthenol) is extremely hygroscopic.

It is also used in the biosynthesis of coenzyme A, which plays a role in a wide range of enzymatic reactions and in cell growth.
Dexpanthenol (Panthenol) helps to keep the skin hydrated by drawing moisture into the skin, making it an effective ingredient in lotions, creams, and ointments.
Dexpanthenol (Panthenol) promotes the healing of minor wounds, cuts, abrasions, burns, and sunburns.

It accelerates tissue regeneration and improves the skin's natural barrier function.
Dexpanthenol (Panthenol) is often used to reduce skin irritation, inflammation, and redness, making it useful in products for sensitive skin or conditions like eczema or psoriasis.
Due to its moisturizing effects, it helps to reduce the appearance of fine lines and wrinkles, making it popular in anti-aging skincare formulations.

Dexpanthenol (Panthenol) is used in shampoos, conditioners, and hair masks to prevent dryness and improve hair texture.
It binds moisture to the hair, leaving it softer, shinier, and more manageable.
Dexpanthenol (Panthenol) helps to repair and restore damaged hair by strengthening hair fibers and preventing split ends.

Some studies suggest that it can help promote hair growth by enhancing the health of hair follicles, though more research is needed in this area.
It acts as an emollient in cosmetic formulations, providing smoothness and softening the skin, which is why it is included in many lotions, lip balms, and makeup products.
In cosmetics like foundation or creams, it improves the texture and consistency, making the product easier to apply and giving it a pleasant feel on the skin.

Dexpanthenol (Panthenol) is used in over-the-counter and prescription ointments for treating skin conditions such as dermatitis, eczema, and minor burns.
Dexpanthenol (Panthenol) is sometimes included in vitamin supplements for its role in skin and energy metabolism, as it is a precursor to Vitamin B5 (pantothenic acid).
It is often a component of creams used to speed up the healing process of ulcers, cuts, and abrasions.

Dexpanthenol (Panthenol) can be used in the recovery of skin after surgeries to aid in quicker healing and reduce scarring.
Dexpanthenol (Panthenol) is used in some foot care products for diabetics to prevent dry skin and improve healing in vulnerable areas of the feet.
In some cases, Dexpanthenol is used in injectable form for patients needing a higher dose of Vitamin B5, particularly in cases of malnutrition or certain metabolic conditions.

Dexpanthenol (Panthenol) is often included in nail care products like nail oils, lotions, and treatments.
It helps to strengthen nails and prevent brittleness by improving moisture retention.
Dexpanthenol (Panthenol) is used in cuticle creams and oils to hydrate and soften the skin around the nails, preventing dry, cracked cuticles.

Dexpanthenol (Panthenol) is used in some eye drops and ointments for dry eyes and eye irritation.
It helps to hydrate the eye surface, soothe inflammation, and promote healing of minor eye injuries or conditions like conjunctivitis.
Dexpanthenol (Panthenol) is sometimes used in eye care products after surgeries, such as cataract removal, to speed up healing and reduce irritation.

Dexpanthenol (Panthenol) is known for its anti-inflammatory properties, making it beneficial for treating skin inflammation.
It helps to calm irritated skin, reducing redness and swelling in cases like rosacea, dermatitis, and allergic reactions.
After procedures such as chemical peels, microdermabrasion, or laser treatments, Dexpanthenol (Panthenol) can help soothe the skin and promote quicker recovery.

Some oral gels and mouth rinses contain Dexpanthenol (Panthenol) to treat canker sores or mouth ulcers.
It promotes healing of the mucosal lining and reduces pain or discomfort associated with these conditions.
Dexpanthenol (Panthenol) is sometimes included in mouthwashes or oral gels to promote the healing of minor gum irritations and prevent dryness in the mouth.

Due to its soothing and moisturizing properties, Dexpanthenol (Panthenol) is a common ingredient in after-sun care products.
It helps to replenish moisture and aid in skin repair after sun exposure, preventing peeling and dryness.
Dexpanthenol (Panthenol) helps to alleviate the symptoms of sunburn, such as redness and irritation, by providing hydration and accelerating skin recovery.

Dexpanthenol (Panthenol) can be found in veterinary products for pets, particularly for treating skin conditions like dry, cracked paws or mild abrasions.
It helps in moisturizing and healing their skin, making it a useful ingredient in dog and cat creams or ointments.
Some pet shampoos and grooming products use Dexpanthenol (Panthenol) to enhance fur softness and shine, similar to its use in human hair care.

Dexpanthenol (Panthenol) is often used in acne treatments to help minimize scarring by promoting faster skin regeneration. ,
It is also known to reduce the inflammation associated with acne breakouts.
It can be helpful in soothing inflamed skin during active acne flare-ups due to its anti-inflammatory properties.

Dexpanthenol (Panthenol) is widely used in products designed for dry, sensitive, or dehydrated skin, including body lotions, face creams, and serums.
By enhancing the skin's ability to retain moisture, Dexpanthenol (Panthenol) helps improve skin elasticity and texture.
During winter months when the skin tends to become dry and cracked, Dexpanthenol (Panthenol) is included in products designed to protect and hydrate the skin.

Dexpanthenol (Panthenol) is often included in topical treatments for chronic skin conditions such as psoriasis and eczema, where it helps to alleviate itching, dryness, and irritation while supporting skin regeneration.
Dexpanthenol (Panthenol) can reduce the inflammation and redness associated with rosacea by calming the skin and providing moisture.
In some cases, Dexpanthenol (Panthenol) is used as a food additive under the code E 304.

It is used as a stabilizing agent or as a source of Vitamin B5 in fortified foods, particularly in health-related food products.
Some sports creams and balms include Dexpanthenol (Panthenol) to treat minor muscle strains, abrasions, and chafing.
Its moisturizing properties help soothe the skin and reduce discomfort caused by friction during physical activity.

Dexpanthenol (Panthenol) is used in post-exercise recovery products for athletes, helping to repair the skin and prevent dehydration after intense physical exertion.
Dexpanthenol (Panthenol) is occasionally used in perfumes and other fragrance products as a fixative.
It helps to prolong the longevity of the scent on the skin and prevents it from evaporating too quickly.

Safety Profile Of Dexpanthenol (Panthenol):
Dexpanthenol (Panthenol) moderately toxic by intravenous route.
Dexpanthenol (Panthenol) a skin and eye irritant.
When heated to decomposition it emits toxic fumes of NOx.

While rare, some individuals may experience mild skin irritation, redness, or itching when using products containing Dexpanthenol (Panthenol), particularly if they have sensitive skin.
Though uncommon, some people may develop an allergic reaction to Dexpanthenol (Panthenol), which could manifest as hives, rash, swelling, or severe itching.
In such cases, discontinuing use of the product is recommended, and medical attention may be necessary.

Prolonged or excessive use of products with Dexpanthenol (Panthenol) can potentially lead to contact dermatitis, an inflammation of the skin characterized by redness, swelling, and itching.
Dexpanthenol (Panthenol)-containing products, such as ointments or creams, accidentally come into contact with the eyes, they may cause irritation or discomfort.

While rare, some formulations can cause stinging, redness, or watering of the eyes.
If ingested or used inappropriately around the eyes in high concentrations, it may cause more significant irritation or even damage to the sensitive eye area.
Dexpanthenol (Panthenol)’s always important to use the product as directed.