Quick Search
CAS: 109-89-7
MF: C4H11N
MW: 73.14
EINECS: 203-716-3
Description
Diethylamine is a colourless, strongly alkaline, fish odour liquid, and highly inflammable.
Diethylamine has an ammonia-like odour and is completely soluble in water.
On burning, diethylamine releases ammonia, carbon monoxide, carbon dioxide, and nitrogen oxides.
Diethylamine is used in the production of pesticides.
Diethylamine is used in a mixture for the production of DEET which goes into the repellents that are found readily in supermarkets for general use.
Diethylamine is a secondary aliphatic amine where both N-substituents are ethyl.
Diethylamine is a conjugate base of a diethylammonium.
A clear colorless liquid with an ammonia-like odor.
Density 5.9 lb / gal. Flash point -15°F.
A respiratory irritant.
Corrosive to the eyes and skin.
Vapors heavier than air.
Toxic oxides of nitrogen produced during combustion.
Diethylamine is incompatible with several chemical substances such as strong oxidisers, acids, cellulose nitrate, some metals, and dicyanofuroxan.
N-nitrosamines, many of which are known to be potent carcinogens, may be formed when diethylamine comes in contact with nitrous acid, nitrates, or atmospheres with high nitrous oxide concentrations.
Diethylamine should be protected from physical damage.
Diethylamine should be kept stored in a cool, dry, well-ventilated location, away from incompatible chemical substances and away from fi re hazard and smoking areas.
The containers should be bonded and grounded for transfer to avoid static sparks.
Diethylamine is an organic compound with the formula (CH3CH2)2NH.
Diethylamine is a flammable, weakly alkaline liquid that is miscible with most solvents.
Diethylamine is a colorless liquid, but commercial samples often appear brown due to impurities.
Diethylamine has a strong ammonia-like odor.
Diethylamine is a secondary amine.
Water-white or colorless liquid with an ammonia-like odor.
Diethylamine, also known as DEA or (C2H5)2nh, belongs to the class of organic compounds known as dialkylamines.
These are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen.
Diethylamine is a colorless liquid which often appears brown due to impurities.
Diethylamine is volatile and has a strong unpleasant odor.
Diethylamine is an ammoniacal and fishy tasting compound.
Diethylamine is found, on average, in the highest concentration within barley and apples.
Diethylamine has also been detected, but not quantified, in a few different foods, such as common grapes, corns, and spinachs.
This could make diethylamine a potential biomarker for the consumption of these foods.
Diethylamine is a potentially toxic compound.
Diethylamine is miscible with water and ethanol.
Diethylamine is a secondary amine with the molecular structure CH3CH2NHCH2CH3.
Diethylamine is a flammable, strongly alkaline liquid.
Diethylamine Chemical Properties
Melting point: -50 °C (lit.)
Boiling point: 55 °C (lit.)
Density: 0.707 g/mL at 25 °C (lit.)
Vapor density: 2.5 (vs air)
Vapor pressure: 14.14 psi ( 55 °C)
Refractive index: n20/D 1.385(lit.)
Fp: −20 °F
Storage temp.: Store below +30°C.
Solubility H2O: soluble1M at 20°C, clear, colorless
Form: Liquid
pka: 11.02(at 40℃)
Color: Clear colorless
Odor: Ammoniacal; sharp, fishy.
PH Range: Strong alkaline
Relative polarity: 0.145
PH: 13 (100g/l, H2O, 20℃)
Explosive limit: 2.0-11.8%(V)
Odor Threshold: 0.048ppm
Water Solubility: soluble
Sensitive: Air Sensitive
Merck: 14,3111
BRN: 605268
Henry's Law Constant: 2.56(x 10-5 atm?m3/mol) at 25 °C (Christie and Crisp, 1967)
Exposure limits NIOSH REL: TWA 10 ppm (30 mg/m3), STEL 25 ppm (75 mg/m3), IDLH 200 ppm; OSHA PEL: TWA 25 ppm; ACGIH TLV: TWA 5 ppm, STEL 15 ppm (adopted).
Stability: Stable. Highly flammable. Incompatible with strong oxidizing agents.
InChIKey: HPNMFZURTQLUMO-UHFFFAOYSA-N
LogP: 0.58 at 20℃
CAS DataBase Reference: 109-89-7(CAS DataBase Reference)
NIST Chemistry Reference: Ethanamine, N-ethyl-(109-89-7)
EPA Substance Registry System: Diethylamine (109-89-7)
Diethylamine is a colourless, strongly alkaline, fish odour liquid, and highly inflammable.
Diethylamine has an ammonia-like odour and is completely soluble in water.
On burning, diethylamine releases ammonia, carbon monoxide, carbon dioxide, and nitrogen oxides.
Diethylamine is used in the production of pesticides.
Diethylamine is used in a mixture for the production of DEET which goes into the repellents that are found readily in supermarkets for general use.
Uses
Diethylamine is manufactured by heating ethyl chloride and alcoholic ammonia under pressure or by hydrogenation of aziridines in the presence of catalysts.
Diethylamine is used as a solvent, as a rubber accelerator, in the organic synthesis of resins, dyes, pesticides, and pharmaceuticals, in electroplating, and as a polymerization inhibitor.
Other applications include uses as a corrosion inhibitor.
Diethylamine was reported noneffective as a skin depigmentator.
Diethylamine, like many of the other short chain aliphatic amines, has achieved widespread industrial use as an intermediate in the manufacture of a number of commercial products.
Among these are included insecticides, pharmaceuticals, textile finishing agents, and corrosion inhibitors (Hawley 1981; Schweizer et al 1978).
Diethylamine is used as a polymerization inhibitor and/or catalyst in the polymer industry and in the manufacture of surfactants and rubber processing accelerators.
This amine also is useful as a depilatory agent for animal skins, as a selective solvent for the removal of impurities from oils, fats, and waxes, and as a flotation agent in the petroleum industry (NIOSH/OSHA 1981; HSDB 1989).
In petroleum industry, in flotation agents, dyes, pharmaceuticals.
Diethylamine has been used to constitute the extraction solvent mixture for the gas chromatography-mass spectrometric (GC-MS) analysis of melamine and related compounds.
Diethylamine has been also been used as a bond breaking agent in a novel ELISA technique to measure the avidity index (AI) of IgG-anti-PT (Immunoglobulin G-anti-pertussis toxin) antibodies.
Diethylamine may be used as:
An organocatalyst for the preparation of β-phosphonomalononitriles and diethyl (2-amino-3- cyano-chromene-4-yl) phosphonic acid esters.
A ligand for the synthesis of (N-heterocyclic carbene)PdCl2(diethylamine) complexes.
A template for the preparation of thermally and hydrothermally stable SAPO-34 (silicoaluminophosphate) molecular sieves.
Production Methods
Diethylamine is produced using the three methods also used for the manufacture of ethylamine with very slight modification.
Diethylamine Synthesis
1. N,N-Diethyl-3-methylbenzamide + Ethylene Glycol + NaOH + Heat
2. Ethylchloride + Ammonia (forms diethylamine HCL)
3. Ethanol + Ammonia + Sulfuric Acid
The most widely used method is the passing of ammonia and ethanol over a catalyst such as alumina or silica (Schweizer et al 1978).
Diethylamine can be separated from the mixture by selective distillations and extractions.
Health Hazard
Diethylamine can be harmful if it is inhaled, swallowed, or in contact with skin.
Vapors can irritate the eyes and cause irritation of the respiratory tract, leading to coughing and chest pain.
Liquid diethylamine can cause severe burns to the eyes and skin.
Vision became misty and halos appeared several hours after workmen were exposed to the vapors of amines such as diethylamine (Grant 1986).
The edema of the corneal epithelium, which is principally responsible for the disturbances in vision, clears after one or more days, depending on the severity of exposure.
Photophobia and discomfort from roughness of the corneal surface also can occur after greater exposure to the amine.
Synonyms
DIETHYLAMINE
N-Ethylethanamine
109-89-7
N,N-Diethylamine
Ethanamine, N-ethyl-
Diethamine
Diaethylamin
Dwuetyloamina
Dietilamina
diethyl amine
Diethyl-amine
Et2NH
(C2H5)2NH
B035PIS86W
CHEBI:85259
MFCD00009032
Diethylamin
N-Ethyl-Ethanamine
Diaethylamin [German]
Dietilamina [Italian]
Dwuetyloamina [Polish]
CCRIS 4792
HSDB 524
EINECS 203-716-3
UN1154
dietylamine
UNII-B035PIS86W
di-ethylamine
AI3-24215
N,N-diethyl amine
diethylamine (DEA)
Diethylamine, 98%
Diethylamine Anhydrous
Diethylamine, BioXtra
HNEt2
DIETHYLAMINE [MI]
DSSTox_CID_1909
DIETHYLAMINE [HSDB]
DIETHYLAMINE [INCI]
EC 203-716-3
Diethylamine, >=99.5%
CHEMBL1189
DSSTox_RID_76397
DSSTox_GSID_21909
Diethylamine, LR, >=99%
(CH3CH2)2 NH
Diethylamine, p.a., 99.0%
DTXSID6021909
STR00027
ZINC1661184
Tox21_202506
STL197470
Diethylamine, for synthesis, 99.0%
AKOS000269031
Diethylamine 2000 microg/mL in Water
UN 1154
Diethylamine, purum, >=99.0% (GC)
NCGC00090709-01
NCGC00090709-02
NCGC00260055-01
CAS-109-89-7
MELPHALAN IMPURITY K [EP IMPURITY]
Diethylamine, SAJ first grade, >=98.0%
D0462
Diethylamine [UN1154] [Flammable liquid]
Diethylamine, SAJ special grade, >=99.0%
FT-0624870
D89660
Diethylamine, puriss. p.a., >=99.5% (GC)
Diethylamine, purified by redistillation, 99.5%
Q414196
J-002340
J-520311
5-Oxo-L-prolyl-L-glutaminyl-L-alpha-aspartyl-O-sulfo-L-tyrosyl-L-threonylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamideN-ethylethanamine (1/1)
