DIETHYLAMINOETHANOL

DIETHYLAMINOETHANOL
(2-(Diethylamino)ethanol= 2-HydroxyTriethylamine = DEAE)

CAS Number: 100-37-8 
EC Number: 202-845-2
SMILES string: CCN(CC)CCO
InChI: 1S/C6H15NO/c1-3-7(4-2)5-6-8/h8H,3-6H2,1-2H3
InChI key: BFSVOASYOCHEOV-UHFFFAOYSA-N
Beilstein Reference: 741863
CHEBI:52153 
EC Number: 202-845-2
UNII: S6DL4M053U
UN number: 2686
Chemical formula: C6H15NO
Systematic Name: Ethanol, 2-(diethylamino)-
Molecular Weight: 117.19

Diethylethanolamine (DEAE) is a chemical compound with the molecular formula C6H15NO.
Diethylaminoethanol (DEAE) is a clear liquid.
2-Diethylaminoethanol, also known as diethylethanolamine or DEAE, belongs to the class of organic compounds known as 1,2-aminoalcohols.
Diethylaminoethanol is a colorless hygroscopic liquid base combining the properties of amines and alcohols. 
DEAE is colorless, hygroscopic liquid base that is used as a vapor phase corrosion inhibitor.

Diethylaminoethanol (DEAE) is a clear liquid. 
Diethylaminoethanol is used as a neutralizing amine for boiler water, coatings, etc.
Diethylaminoethanol is an organic of amine and alcohol substituents. 

Diethylaminoethanol is a colorless liquid base combining the properties of amines and alcohols. 
Diethylaminoethanol is soluble in water, alcohol, and benzene and it is combustible.
2-diethylaminoethanol is a member of the class of ethanolamines that is aminoethanol in which the hydrogens of the amino group are replaced by ethyl groups.
Diethylaminoethanol is a member of ethanolamines, a tertiary amino compound and a primary alcohol.

APPLICATIONS AND USES

2-Diethylaminoethanol (DEAE) is used as a curing agent for resins, as an emulsifying agent (soaps, cosmetics, cutting oils) and as a fabric softener.
commercially used as neutralizing agent and CO2 scavenger in boiler water
Diethylaminoethanol (DEAE) neutralizes amine formulation selected to use in a wide range of boiler condensate systems.
Diethylaminoethanol is an effective oxygen scavenger and passivator. 

Diethylaminoethanol can be used in boiler water treatment with diethylhydroxylamine, and diethylaminoethanol can also be used as a curing agent for synthetic resin, a softening agent for textiles, an acidic medium, an emulsifier and a rust inhibitor.
2-Diethylaminoethanol-d10 Hydrochloride is an intermediate in the synthesis of Flurazepam-d10 Dihydrochloride (F500802).
Diethylaminoethanol is used as a neutralizing agent in boiler treatment and as a chemical intermediate in the production of floor polishes, pesticides, coatings, and pharmaceuticals.
Diethylaminoethanol functions as intermediate.
2-Diethylaminoethanol, reagent is used as a precursor chemical to procaine.

In condensate and steam lines, Diethylaminoethanol is used as a corrosion inhibitor because it neutralizes carbonic acid and scavenging oxygen.
Diethylaminoethanol is used in Army boiler plants to prevent internal corrosion of condensate return lines.
2-Diethylaminoethanol, 99% Cas 100-37-8 - used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen.

The use of neutralizing amines, notably DEAE, morpholine, and cyclohexylamine, play a large role in the curtailment of condensate corrosion.
Diethylaminoethanol applications include: Water-soluble salts, fatty acid derivatives, textile softeners, pharmaceuticals, antirust compositions, emulsifying agents in acid media, derivatives containing tertiary amine groups, curing agent for resins.
Diethylaminoethanol applications are corrosion inhibitors and anti-scaling agents.
Diethylaminoethanol is used in the formulations of Pharmaceuticals, Agrochemicals, Diethylaminoethanol is used in Corrosion Inhibitor, Detergents, Intermediate for Anti Malarials.

Diethylaminoethanol (DEAE) is used as a neutralizing agent and CO2 scavenger in boiler water.
The ideal vapor pressure and vapor-liquid distribution properties of DEAE make it the best choice for pH adjustment of process water.
Primarily a corrosion inhibitor in steam and condensate lines due to its neutralizing carbonic acid and scavenging oxygen, diethylaminoethanol is prepared in mass quantity for commercial and industrial use.
DEAE is a popular choice for treating process water in boilers and steam heat systems since Diethylaminoethanol neutralizes corrosive agents within the system and scavenges CO2.
Diethylaminoethanol also provides an ideal solution for adjusting the pH balance of process water due to its vapor pressure and vapor-liquid distribution properties.
DEAE is also used in pharmaceuticals and various ink production processes, though its primary application remains water treatment solutions.

Elective formose reactions were achieved by diethylaminoethanol as a catalyst at 100°C in the presence and the absence of D-fructose as co-catalyst.
Diethylaminoethanol (DEAE) is added to the water in boilers in steam humidification systems to minimize pipe corrosion.
Diethylaminoethanol is also used as an alkalizing agent in HVAC systems to neutralize carbonic acids.
When DEAE is used in an open ventilation system, it can deposit on all available surfaces including works of art.

DEAE produces an oily residue that can soften varnishes.
Diethylaminoethanol is used as: Finishing agents, Fuels and fuel additives, Intermediates, Paint additives and coating additives not described by other categories, Plastics, Processing aids, specific to petroleum production, Resale, Surface active agents, Fuels and related products, Paints and coatings, Water treatment products, Paint and coating manufacturing, Petrochemical manufacturing, Petroleum lubricating oil and grease manufacturing, Plastic material and resin manufacturing, Primary metal manufacturing and Wholesale and retail trade.
Information on 26 consumer products that contain 2-Diethylaminoethanol in the following categories is provided are auto products, commercial / institutional, home maintenance, and personal care. 
2-Diethylaminoethanol is used in all other basic organic chemical manufacturing, all other chemical product and preparation manufacturing and all other petroleum and coal products manufacturing.
2-Diethylaminoethanol is used as a precursor in the production of a variety of chemical commodities such as the local anesthetic procaine.

2-Diethylaminoethanol can be reacted with 4-aminobenzoic acid to make procaine. 
DEAE can be used as a precursor for DEAE-cellulose resin, which is commonly used in ion exchange chromatography.
In solution, 2-Diethylaminoethanol can decrease the surface tension of water when the temperature is increased.
Diethylethanolamine is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen.
2-Diethylaminoethanol is used as a neutralizing amine for boiler water, coatings, etc.
Beyond its application in the water treatment segment, DEAE is also used as a neutralizing amine for industrial coatings and an intermediate for various surfactants.

N,N-Diethylethanolamine (DEEA), which can be prepared from renewable resources, represents a candidate alkanolamine for CO2 removal from gaseous streams.
Diethylaminoethanol is used as a neutralizing agent in boiler treatment, and as a chemical intermediate in the production of floor polishes, pesticides, coatings, and pharmaceuticals.
Diethylethanolamine can be used as a precursor chemical to procaine. 

Diethylaminoethanol is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen. 
Diethylaminoethanol is used for the synthesis of drugs in the pharmaceutical industry and as a catalyst for the synthesis of polymers in the chemical industry. 
Diethylaminoethanol is also used as a pH stabilizer.

Diethylaminoethanol is used as;
as a buffering agent in cosmetics.
as a component of filler/sealing compounds and household cleaners/polishers (e.g. in shoe, leather, car).
as a catalyst for the synthesis of polymers;
as a pH stabiliser;
as a component of corrosion inhibitors in closed systems, surface-active agents, cleaning/washing agents, cutting
fluids, paint, lacquers and varnishes and surface treatment agents;
in metal working fluids;
as an additive in coatings, concrete and cement; and
in the manufacture of emulsifying agents and special soaps.
as an intermediate in petroleum and gas processing chemicals; and
in the production of pharmaceutical ingredients.

Diethylethanolamine is used as a corrosion inhibitor in steam and condensate lines. 
Diethylaminoethanol is also used as a textile softener, an emulsifier in acid media, and a curing agent for resins.
An oxygen scavenger for boiler water includes ascorbic acid neutralized with diethylaminoethanol.
The diethylaminoethanol provides condensate treatment for the long and short steam lines and improves the scavenging of the ascorbic acid.
Diethylaminoethanol is an effective oxygen scavenger and passivator. It can be used in boiler water treatment with diethylhydroxylamine, and diethylaminoethanol can also be used as a curing agent for synthetic resin, a softening agent for textiles, an acidic medium, an emulsifier and a rust inhibitor.

PHYSICAL AND CHEMICAL PROPERTIES

Diethylaminoethanol is soluble in water, alcohol, and benzene.
Diethylaminoethanol’s chemical family: alkanolamine.
Diethylaminoethanol is extremely volatile in the presence of water.
Diethylaminoethanol is easy to change color in long-term storage or temperature environments at 40 °c.

Diethylaminoethanol is chemically stable and able to absorb carbon dioxide (CO2) from its surroundings.
Diethylaminoethanol appears as a colorless liquid.
Diethylaminoethanol is a colorless liquid with a nauseating, ammonia-like odor.
Diethylaminoethanol is less dense than water.

Diethylaminoethanol’s vapors heavier than air.
Diethylaminoethanol is soluble in all proportions in water; sol in alc, ether, acetone, benzene, petroleum ether.
Diethylaminoethanol is a colorless liquid, with slightly ammonia flavor. 
Soluble in alcohol, water, ketone, ethylene glycol, glycerol and glycol ether. 
It is difficult or insoluble in non-polar solvents such as aliphatic hydrocarbons and the like. An azeotrope may be formed with water. 
It is easy to change color in long-term storage or temperature environment at 40 °c. 

Chemical Stability: Stable under normal temperatures and pressures.
Stereochemistry: ACHIRAL
Formula Weight: 117.19
Melting point: -70°
Boiling Point: 161-163°
Flash Point: 52°(125°F)
Density: 0.883
Chemical formula: C6H15NO
Molar mass: 117.192 g·mol−1
Molecular Weight: 117.19    
Appearance: Colourless liquid

Odor: Ammoniacal
Density: 884 mg mL−1
Melting point: −70 °C; −94 °F; 203 K 
Boiling point: 161.1 °C; 321.9 °F; 434.2 K
Solubility in water: miscible
log P: 0.769
Vapor pressure: 100 Pa (at 20 °C)
Refractive index (nD): 1.441–1.442
Boiling Point: 325 °F at 760 mm Hg
Boiling range: 158 - 163.5C (316 - 326F)
Melting Point: -94 °F
Freezing point: -70 °C
Flash Point: 140 °F (52 °C)
Specific Gravity: 0.89
Solubility: 1000000 mg/L at 25 °C
Density: 0.8921 at 77 °F, 0.8921 at 20 °C
Density: 0.88-0.89 (@20 c)
Relative density (water = 1): 0.88
Vapor Density: 4.03 (Air= 1)
Vapor Pressure: 21 mmHg at 68 °F, 21 mmHG at 20 °C
Viscosity: 5 mPa-s at 20 °C
Viscosity @ 20C: 3.5 cps
Heat of Vaporization: 383.9 kJ/kg
Surface Tension: 29.2 mN/m at 20 °C

LogP: 0.050
XLogP3-AA: 0.3    
Hydrogen Bond Donor Count: 1    
Hydrogen Bond Acceptor Count: 2    
Rotatable Bond Count    : 4    
Exact Mass: 117.115364102    
Monoisotopic Mass: 117.115364102    
Topological Polar Surface Area: 23.5 Ų    
Heavy Atom Count: 8    
Formal Charge: 0    
Complexity: 43.8    
Isotope Atom Count: 0    
Defined Atom Stereocenter Count: 0    
Undefined Atom Stereocenter Count: 0    
Defined Bond Stereocenter Count: 0    
Undefined Bond Stereocenter Count: 0    
Covalently-Bonded Unit Count: 1    
Compound Is Canonicalized: Yes    
Flash point: 103-140°F
Stability During Transport: Stable
Odor Threshold: Absolute perception limit in air = 0.011 ppm
Index of Refraction: 1.4412 at 20 °C
pKa: 9.87 at 20 °C (conjugate acid)
Hygroscopic liquid base combining the properties of amines & alc; wt/gal: 7.14 lb at 20 °C
Cubic expansion coefficient = 1.07x10-3 1/K
Specific heat = 2.42 kJ/kg-K
Specific electrical conductivity = 1.1x10-3 1/ohm-cm

NMR: 7047
IR: 6294
ppm per mg/m⁻³, (20 °C, 1 bar): 0.205
Ionisation Energy, eV: 8.58
Water Solubility: 665.0 mg/mL
pKa (Strongest Acidic): 15.59    
pKa (Strongest Basic): 9.55    
Physiological Charge: 1
Polar Surface Area: 23.47 Å2    
Rotatable Bond Count: 4    
Refractivity: 35.78 m3·mol-1    
Polarizability: 14.46 Å3    
Number of Rings: 0    
Bioavailability: 1    
Rule of Five: Yes    
Ghose Filter: No    
Veber's Rule: Yes    
MDDR-like Rule: No
Appearance (Clarity): Clear
Appearance (Colour): Colourless to slight yellow
Appearance (Form): Liquid
Assay (GC): min. 99%
Characteristic ammoniacal odor.
Saturation Concentration: About 0.18% (1800 ppm) at 25 C 
Evaporization number: 0.17 (butyl acetate = 1)
Critical temperature: 343
Critical pressure: 26.15
Solubility in water: Miscible
Viscosity: 4.022 cp (25 C)
Surface tension: 29.2 g/s2 at 20 C
Refractive index: 1.4389 (20 C)
Dielectric constant: 9.1 (20 C)
pKa/pKb: 4.13 (pKb)
Heat of vaporization: 45.0 kJ/mol
Storage: Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. 

PRODUCTION

Diethylaminoethanol can be produced by action of ethylene chlorohydrin on diethylamine.
Diethylaminoethanol can be produced by action of ethylene oxide on diethylamine.
DEAE can also be conveniently obtained from renewable sources.
Diethylethanolamine is prepared commercially by the reaction of diethylamine and ethylene oxide.
Diethylethanolamine is also possible to prepare by the reaction of diethylamine and ethylene chlorohydrin.

Diethylaminoethanol is synthesized by employing the reaction of diethylamine with ethylene oxide or ethylene chlorhydrin, and by reducing diethyl amino acetic ester with metallic sodium and alcohol.
Diethylaminoethanol is prepared by; Ethylene oxide is added to diethylamine from diethylamine and ethylene oxide, and the reaction is carried out at a certain temperature, and the obtained crude product is distilled under reduced pressure to a pure product.
ethylene oxide is added to diethylamine from diethylamine and ethylene oxide, and the reaction is carried out at a certain temperature, and the obtained crude product is distilled under reduced pressure to a pure product.
Diethylaminoethanol derives from an ethanolamine. 
Diethylaminoethanol derives from a hydride of a triethylamine.

SYNONYMS

.beta.-(diethylamino)ethanol
.beta.-(diethylamino)ethyl alcohol
(2-Hydroxyethyl)diethylamine
(DIETHYLAMINO)ETHANOL
100-37-8
11066-EP2269610A2
11066-EP2277848A1
11066-EP2277867A2
11066-EP2280003A2
11066-EP2289510A1
11066-EP2292576A2
11066-EP2295409A1
11066-EP2305677A1
11066-EP2305682A1
11066-EP2308840A1
11066-EP2308879A1
11066-EP2311842A2
11066-EP2314590A1
11066-EP2314593A1
11066-EP2316457A1
11066-EP2316458A1
11066-EP2316825A1
11066-EP2316826A1
11066-EP2316827A1
11066-EP2316828A1
137648-EP2270505A1
137648-EP2292088A1
2-(DIETHYLAMINO)ETHANOL
2-(DIETHYLAMINO)ETHYL ALCOHOL
2-(diethylamino)-1-ethanol
2-(diethylamino)-ethanol
2-(Diethylamino)Ethan-1-Ol
2-(Diethylamino)ethanol
2-(Diethylamino)ethanol, >=99.5%
2-(Diethylamino)ethanol, >=99%
2-(Diethylamino)ethanol, 99%
2-(Diethylamino)ethanol, purum, >=99.0% (GC)
2-(Diethylamino)ethyl alcohol
2-(N,N-diethylamino)-ethanol
2-DIETHYLAMINOETHYL ALCOHOL
2-diethyl aminoethanol
2-Diethylamino
2-diethylamino-ethanol
2-Diethylaminoethanol [UN2686] [Corrosive]
2-Diethylaminoethanol 100 microg/mL in Acetonitrile
2-Diethylaminoethanol, 9CI
2-Diethylaminoethyl alcohol
2-Hydroxytriethylamine
2-Hydroxytriethylamine
2-hydroxytriethylamine
2-N-(Diethylamino)ethanol
2-N-DIETHYLAMINOETHANOL
2-N-diethylaminoethanol
83206-48-8
A 22
ADAL1185323
AI3-16309
AKOS000119883
BBL012211
beta-(Diethylamino)ethanol
beta-(Diethylamino)ethyl alcohol
BETA-DIETHYLAMINOETHANOL
BETA-DIETHYLAMINOETHYL ALCOHOL
BETA-HYDROXYTRIETHYLAMINE
beta-Hydroxytriethylamine
beta.-(Diethylamino)ethanol
beta.-(Diethylamino)ethyl alcohol
BP-20552
CAS-100-37-8
CCRIS 4793
CHEBI:52153
CHEMBL1183
D0465
D88192
DB-012722
DEAE
DEAE
DEEA
Dehydasal
DIETHYL ETHANOLAMINE
DIETHYL-(2-HYDROXYETHYL)AMINE
DIETHYL(BETA-HYDROXYETHYL)AMINE
DIETHYLAMINOETHANOL
DIETHYLETHANOLAMINE
DIETHYLMONOETHANOLAMINE
Diaethylaminoaethanol
Diathylaminoathanol
diethyl ethanolamine
Diethyl ethanolamine Diethylaminoethanol 2-Hydroxytriethylamine
Diethyl(2-hydroxyethyl)amine
Diethyl(2-hydroxyethyl)amine
Diethylamino ethanol
Diethylaminoethanol
Diethylethanolamine
Diethylmonoethanolamine
diethylmonoethanolamine
DSSTox_CID_1837
DSSTox_GSID_21837
DSSTox_RID_76358
DTXSID5021837
EC 202-845-2
EINECS 202-845-2
Ethanol, 2-(diethylamino)-
ETHANOL,2-DIETHYLAMINO
F0001-0014
HMS3039I08
HSDB 329
J-520312
MCULE-8115329454
MFCD00002850
MKS
MLS002174251
N-(2-HYDROXYETHYL)DIETHYLAMINE
N-(beta-hydroxyethyl)diethylamine
N-(Diethylamino)ethanol
N-(hydroxyethyl)-N,N-diethyl amine
N-DIETHYLAMINOETHANOL
N, N-Diethylethanolamine
N,N-DIETHYL-2-AMINOETHANOL
N,N-DIETHYL-N-(BETA-HYDROXYETHYL)AMINE
N,N-DIETHYL(2-HYDROXYETHYL)AMINE
N,N-DIETHYLETHANOLAMINE
N,N-DIETHYLMONOETHANOLAMINE
N,N-diethyl ethanol amine
N,N-Diethyl-2-aminoethanol
N,N-Diethyl-2-hydroxyethylamine
n,n-diethyl-aminoethanol
N,N-Diethyl-N-(.beta.-hydroxyethyl)amine
N,N-Diethylethanolamine
N,N-Diethylmonoethanolamine
NCGC00090925-01
NCGC00090925-02
NCGC00090925-03
NCGC00253920-01
NCGC00259014-01
NSC8759
Pennad 150
Perdilaton
Q209373
S6DL4M053U
SBB058521
SCHEMBL3114
SMR001261425
ST51023433
STL163552
UNII-S6DL4M053U
VS-03234
WLN: Q2N2 & 2
X5348
ZINC388479
N,N,-Diethylethanolamine