DIETHYLAMINOETHANOL

Diethylaminoethanol is colorless liquid with a nauseating, weak, ammonia odor; hygroscopic; very soluble in water; soluble in alcohol, ether acetone, benzene, and petroleum ether.
Diethylaminoethanol, also known as DEAE, is a chemical compound with the molecular formula C4H11NO. 
Diethylaminoethanol is an organic compound that belongs to the class of ethanolamines. 

CAS Number: 100-37-8
Molecular Formula: C6H15NO
Molecular Weight: 117.19
EINECS Number: 202-845-2

Diethylaminoethanol is characterized by the presence of two ethyl groups and an amino group attached to a central carbon atom. 
Diethylaminoethanol is a clear, colorless liquid with a strong ammonia-like odor.

Diethylaminoethanol is a member of the class of ethanolamines that is aminoethanol in which the hydrogens of the amino group are replaced by ethyl groups. 
Diethylaminoethanol is a member of ethanolamines, a tertiary amino compound and a primary alcohol. 
Diethylaminoethanol derives from an ethanolamine. 

Diethylaminoethanol derives from a hydride of a triethylamine.
Diethylaminoethanol is a clear liquid. 
Diethylaminoethanol is used as a neutralizing amine for boiler water, coatings, etc.

The ideal vapor pressure and vapor-liquid distribution properties of Diethylaminoethanol make it the best choice for pH adjustment of process water.
Beyond its application in the water treatment segment, Diethylaminoethanol is also used as a neutralizing amine for indrustrial coatings and an intermediate for various surfactants.

Diethylaminoethanol is a tertiary amine produced by reaction of ethylene oxide or ethylene chlorhydrin and diethylamine (RTECS 1988). 
Itokazu (1987) has modified this process for manufacture of Diethylaminoethanol without eventual discoloration.

Diethylaminoethanol a colorless liquid. 
Diethylaminoethanol flash point 103-140°F. 
Diethylaminoethanol less dense than water . 

Diethylaminoethanol vapors heavier than air. 
Produces toxic oxides of nitrogen during combustion. 
Diethylaminoethanol causes burns to the skin, eyes and mucous membranes.

Diethylethanolamine (DEAE) is a chemical compound with the molecular formula C6H15NO. 
Diethylaminoethanol is used as a precursor in the production of a variety of chemical commodities such as the local anesthetic procaine. 
Diethylaminoethanol can be reacted with 4-aminobenzoic acid to make procaine. 

Diethylaminoethanol can be used as a precursor for DEAE-cellulose resin, which is commonly used in ion exchange chromatography. 
Diethylaminoethanol can also be conveniently obtained from renewable sources. 
Diethylaminoethanol is chemically stable and able to absorb carbon dioxide (CO2) from its surroundings. 

Diethylaminoethanol can decrease the surface tension of water when the temperature is increased.
Diethylaminoethanol, also known as DEAE, belongs to the class of organic compounds known as 1,2-aminoalcohols. 
These are organic compounds containing an alkyl chain with an amine group bound to the C1 atom and an alcohol group bound to the C2 atom. 

Based on a literature review a significant number of articles have been published on Diethylaminoethanol.
Diethylaminoethanol has a relatively simple chemical structure consisting of a central carbon atom (C) bonded to two ethyl groups (C2H5), an amino group (NH2), and a hydroxyl group (OH).
Diethylaminoethanols chemical formula is C4H11NO.

Diethylaminoethanol can be synthesized through a chemical reaction known as the Mannich reaction, which typically involves the condensation of formaldehyde, diethylamine, and a compound containing a carbonyl group (such as acetone). 
This reaction results in the formation of DEAE and related compounds.

Diethylaminoethanol is known for its strong ammonia-like odor, which can be pungent and unpleasant. 
This characteristic odor is a result of its chemical structure and can make it easily distinguishable.
Diethylaminoethanol belongs to the class of chemicals known as alkanolamines, which are organic compounds containing both amino (NH2) and hydroxyl (OH) functional groups. 

These compounds often exhibit amphiphilic properties, making them useful in various applications, such as surfactants and corrosion inhibitors.
Diethylaminoethanol is considered to be biodegradable under certain environmental conditions. 
Diethylaminoethanols biodegradability makes it a relatively environmentally friendly chemical in certain applications.

Melting point: -70 °C
Boiling point: 161 °C (lit.)
Density: 0.884 g/mL at 25 °C (lit.)
vapor density: 4.04 (vs air)
vapor pressure: 1 mm Hg ( 20 °C)
refractive index: n20/D 1.441(lit.)
Flash point: 120 °F
storage temp.: Store below +30°C.
solubility: soluble
form: Crystalline Powder
pka: 14.74±0.10(Predicted)
color: White to pale yellow
PH Range: 10
Odor: Characteristic ammoniacal odor
PH: 11.5 (100g/l, H2O, 20℃)
explosive limit: 0.7%(V)
Water Solubility: soluble
FreezingPoint: -70℃
Merck: 14,3112
BRN: 741863
Exposure limits    NIOSH REL: TWA 10 ppm (50 mg/m3), IDLH 100 ppm; OSHA PEL: TWA 10 ppm; ACGIH TLV: TWA 2 ppm (adopted).
Stability: Stable. Flammable. Incompatible with strong oxidizing agents, acids. Moisture sensitive. Hygroscopic.
InChIKey: BFSVOASYOCHEOV-UHFFFAOYSA-N
LogP: 0.21 at 23℃

Diethylaminoethanol exhibits surfactant properties due to its amphiphilic nature. 
This means it can lower the surface tension of liquids, making it useful in applications where emulsification and dispersion are required. 
Surfactants like DEAE are commonly found in products like detergents, shampoos, and emulsions.

Diethylaminoethanol can be used as a pH regulator or buffer in various chemical processes and formulations. 
Diethylaminoethanols basic nature allows it to act as a pH adjuster, helping to maintain the desired pH level in a solution.

Diethylaminoethanol is used in the formulation of emulsions, where it helps stabilize the mixture of two immiscible liquids, such as oil and water. 
Emulsions are common in the cosmetics, pharmaceutical, and food industries.
In the petroleum industry, Diethylaminoethanol is employed as a component of corrosion inhibitors. 

These inhibitors are added to pipelines and equipment to protect them from corrosion, extending their lifespan.
Diethylaminoethanol may be used as a fuel additive to enhance the performance and stability of fuels. 
Diethylaminoethanol can improve combustion efficiency and reduce emissions, making it a potential component of fuel formulations.

While not as common as other ingredients, Diethylaminoethanol can be found in some pharmaceutical formulations. 
Diethylaminoethanol may serve various roles, including pH adjustment and emulsification in certain drug products.
Due to its surfactant properties, Diethylaminoethanol can be used in industrial cleaning solutions where effective removal of oils and greases is required.

Diethylaminoethanol can play a role in water treatment processes, particularly in controlling pH levels and aiding in the removal of certain contaminants.
Diethylaminoethanol is often used in chemical research and development laboratories as a versatile chemical reagent for various reactions and experiments.

Diethylaminoethanol is generally considered to be biodegradable under specific environmental conditions, which can be advantageous in applications where environmental impact is a concern.
In the cosmetics and personal care industry, Diethylaminoethanol may be used in formulations such as creams, lotions, and shampoos for its emulsifying and pH-adjusting properties.

Diethylaminoethanol is an aminoalcohol. 
Amines are chemical bases. 
They neutralize acids to form salts plus water. 

These acid-base reactions are exothermic. 
The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. 
Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. 

Diethylaminoethanol flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. 
Diethylaminoethanol can react with strong oxidizers and acids.

Preparation Of Diethylaminoethanol:
Diethylethanolamine is prepared commercially by the reaction of diethylamine and ethylene oxide.
(C2H5)2NH + cyclo(CH2CH2)O → (C2H5)2NCH2CH2OH
Diethylaminoethanol is also possible to prepare it by the reaction of diethylamine and ethylene chlorohydrin.

Metabolism Of Diethylaminoethanol:
The absorption of Diethylaminoethanol in healthy adult rats is very rapid, reaching a peak plasma level in 30 min (Bismut et al 1986). 
The biological half-life is 3.5 h with 39% of the excreted product appearing in the urine after 48 h (Bismut et al 1986). 

In an earlier study, Schulte et al (1972) demonstrated that in rats, following a single oral dose, excretion occurs mainly through the kidneys with 37-59% being eliminated in the first 24 h. After 48 h, elimination was independent of dose. 
The brain and spinal cord showed the highest concentration after 7 d. 
Metabolites produced were observed to be diethylaminoethanol N-oxide, diethylaminoacetic acid, and ethylaminoethanol.

Uses Of Diethylaminoethanol:
Diethylaminoethanol is used water-soluble salts; textile softeners; antirust formulations; fatty acid derivatives; pharmaceuticals; curing agent for resins; emulsifying agents in acid media; organic synthesis.
Diethylethanolamine can be used as a precursor chemical to procaine. 

Diethylaminoethanol is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen. 
Diethylaminoethanol is used in the production of surfactants, which are compounds that lower the surface tension of liquids. 
Surfactants are found in a wide range of products, including detergents, shampoos, soaps, and emulsions. 

Diethylaminoethanol's surfactant properties help create stable mixtures of immiscible substances like oil and water.
In the petroleum industry, Diethylaminoethanol is utilized in the formulation of corrosion inhibitors. 
These chemicals are added to pipelines and equipment to protect them from rust and corrosion, extending their lifespan.

Diethylaminoethanol is sometimes added to fuel formulations as an additive to enhance combustion efficiency and reduce emissions. 
Diethylaminoethanol can act as a stabilizer or octane enhancer, improving fuel performance.

Diethylaminoethanol is used in emulsion formulations to stabilize mixtures of liquids that would otherwise separate, such as oil and water. 
This is valuable in industries like cosmetics, pharmaceuticals, and food processing.
Diethylaminoethanol can act as a pH regulator or buffer in various chemical processes and formulations. 

Diethylaminoethanols basic nature allows it to adjust and maintain the desired pH level in a solution.
Diethylaminoethanol is found in industrial cleaning solutions where effective removal of oils and greases is essential. 
Diethylaminoethanols surfactant properties aid in cleaning and degreasing applications.

Diethylaminoethanol can be employed in water treatment processes to control pH levels and assist in the removal of specific contaminants.
While less common, Diethylaminoethanol may be included in some pharmaceutical formulations. 
Diethylaminoethanol can serve various roles, including pH adjustment and emulsification in certain drug products.

Diethylaminoethanol is a versatile chemical reagent used in chemical research and development laboratories for various reactions and experiments.
Diethylaminoethanol is generally considered biodegradable under specific environmental conditions, which can be advantageous in applications where environmental impact is a concern.

In the cosmetics and personal care industry, Diethylaminoethanol can be found in formulations such as creams, lotions, shampoos, and conditioners for its emulsifying and pH-adjusting properties.
Diethylaminoethanol may be used in food processing and manufacturing as an emulsifying agent or pH regulator in certain food products.

Diethylaminoethanol is used for the synthesis of drugs in the pharmaceutical industry and as a catalyst for the synthesis of polymers in the chemical industry. 
Diethylaminoethanol is also used as a pH stabilizer.
Diethylethanolamine is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen.

Diethylaminoethanol is used in the formulation of corrosion inhibitors and fuel additives to protect pipelines and equipment from corrosion and improve the properties of fuels.
Diethylaminoethanol is utilized as a chemical intermediate in the synthesis of other organic compounds and surfactants.

Diethylaminoethanol may be used in some cosmetic and personal care products due to its amphiphilic properties and emulsifying abilities.
Diethylaminoethanolcan be found as a component in some pharmaceutical formulations.
Diethylaminoethanol serves as a useful reagent in chemical research and development due to its unique chemical properties.

Diethylaminoethanol is used in the following products: coating products, pH regulators and water treatment products, laboratory chemicals, lubricants and greases, metal working fluids and adhesives and sealants.
Diethylaminoethanol is used in the following areas: mining.
Diethylaminoethanol is used for the manufacture of: , chemicals and wood and wood products.

Release to the environment of Diethylaminoethanol can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release, in the production of articles and as an intermediate step in further manufacturing of another substance (use of intermediates).
Diethylaminoethanol is used in the production of certain surfactants, which are compounds that reduce the surface tension of liquids. 

Surfactants have applications in detergents, emulsifiers, and foaming agents.
Diethylaminoethanol is employed in the formulation of corrosion inhibitors to protect metal surfaces from rust and corrosion. 
These inhibitors are used in various industries, including oil and gas.

Diethylaminoethanol is sometimes added to fuel formulations as an additive to improve combustion efficiency and reduce emissions. 
In this context, it can act as a stabilizer or octane enhancer.

Diethylaminoethanol is used in the polymer industry for the production of certain types of polymers and resins.
Diethylaminoethanol can be utilized in the synthesis of pharmaceutical compounds, although its use in pharmaceuticals is relatively limited compared to other chemicals.
Diethylaminoethanol serves as an intermediate in the synthesis of other chemicals. 

Diethylaminoethanol can be modified to create compounds with various chemical functionalities.
Diethylaminoethanol is used as an intermediate in the synthesis of other chemicals, such as surfactants and pharmaceuticals.
Diethylaminoethanol can be used in the formulation of corrosion inhibitors to protect metal surfaces from rust and corrosion.

Diethylaminoethanol is sometimes used as an additive in fuel formulations to improve combustion efficiency and reduce emissions.
Diethylaminoethanol is employed in the production of certain polymers and resins.
Diethylaminoethanol can be used in the synthesis of pharmaceutical compounds.

Diethylethanolamine is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen. 
Diethylaminoethanol use as a chemical intermediate for production of emulsifiers, detergents, and solubilizers. 

Diethylaminoethanol is also an intermediate for manufacturing cosmetics; textile finishing agents, fabric softeners, and dyes; drugs and pharmaceuticals, and fatty acid. 
Diethylaminoethanol is also used in antirust compositions, and acts as a curing agent for resins.

Safety Of Diethylaminoethanol:
Diethylethanolamine is an irritant to the eyes, skin, and respiratory system. 
The Occupational Safety and Health Administration and the National Institute for Occupational Safety and Health have set occupational exposure limits for workers handling the chemical at 10 ppm (50 mg/m3) over an eight-hour workday

There is a lack of data regarding human toxicity of Diethylaminoethanol. 
The greatest industrial hazard however, is thought to be to the eyes from contact with the fluid, which is comparable in severity to ammonium hydroxide as an eye irritant (ACGIH 1980).
Diethylaminoethanol is permitted food and Drug Administration for some applications as a food additive. 

Applications include protective coatings for fresh fruits and vegetables, and as an additive in steam which directly contacts food products (excluding milk products). 
The National Research Council Committee on Toxicology (NRC 1983) has concluded that data on long-term, low-level airborne exposures of animals to Diethylaminoethanol for extrapolation to human health risks are severely lacking. 

This, combined with the lack of data concerning the concentrations of Diethylaminoethanol in humidified buildings did not allow sufficient information to set guidelines for long-term exposures or estimate the health risks from such exposures. 
The NRC was able to make some general recommendations based on the assumption that the nitrosation reactions (below) may occur, and that the amine should be considered as hazardous as the nitroso compound formed from it.

Synonyms Of Diethylaminoethanol:
2-(diethylamino)ethanol
2-(dimethylamino)ethanol hydrochloride
2-(N,N-dimethylamino)ethanol hydrochloride
2-diethylaminoethanol
2-diethylaminoethanol hydrochloride
2-diethylaminoethanol hydrochloride, 14C-labeled
2-diethylaminoethanol sulfate (2:1)
2-diethylaminoethanol tartrate
2-diethylaminoethanol, sodium salt
DEAE
deanol hydrochloride
diethylaminoethanol
diethylethanolamine
ethanol, 2-(dimethylamino)-, hydrochloride (1:1)
ethanol, 2-dimethylamino-, hydrochloride
N,N-diethylethanolamine