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DIETHYLENE GLYCOL MONOETHYL ETHER

Diethylene Glycol Monoethyl Ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals. Diethylene Glycol Monoethyl Ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. Diethylene Glycol Monoethyl Ether is a diether, a primary alcohol and a hydroxypolyether.Diethylene Glycol Monoethyl Ether derives from a diethylene glycol.

CAS Number: 111-90-0

SYNONYM: 
Ethanol, 2-(2-ethoxyethoxy); Ethanol, 2-(β-ethoxyethoxy); Diethylene glycol ethyl ether; Diglycol monoethyl ether; Dioxitol; Dowanol DE; Ethylene diglycol monoethyl ether; Poly-Solv DE; Solvolsol; Carbitol; Ethyl carbitol; Transcutol; Ethyl digol; Ektasolve DE; Diethylene Glycol Monoethyl Ether; 1-Hydroxy-3,6-dioxaoctane; O-Ethyl digol; Ethanol, 2,2′-oxybis-, monoethyl ether; 3,6-Dioxa-1-octanol; Ethyldiethylene glycol; Carbitol Solvent Low; Transcutol P; Ethyl Diglysolv; Trivalin SF; Transcutol CG; Shihozoru DG; Transcutol HP; Seahosol DG; Seahosol DG-L; Seahosol DG-S; Glycol ether de; EDG;

2-(2-Ethoxyethoxy) ethanol, also known under many trade names, is the organic compound with the formula CH3CH2OCH2CH2OCH2CH2OH. Diethylene Glycol Monoethyl Ether is a colorless liquid. Diethylene Glycol Monoethyl Ether is a popular solvent for commercial applications. Diethylene Glycol Monoethyl Ether is produced by the ethoxylation of ethanol.
Diethylene Glycol Monoethyl Ether is a solvent for dyes, nitrocellulose, paints, inks, and resins. Diethylene Glycol Monoethyl Ether is a component of wood stains for wood, for setting the twist and conditioning yarns and cloth, in textile printing, textile soaps, lacquers, penetration enhancer in cosmetics, drying varnishes and enamels, and brake fluids. Diethylene Glycol Monoethyl Ether used to determine the saponification values of oils and as a neutral solvent for mineral oil-soap and mineral oil-sulfated oil mixtures (giving fine dispersions in water).

Solvent Diethylene Glycol Monoethyl Ether is a very polar, slow evaporating, water miscible solvent with a low odor. Diethylene Glycol Monoethyl Ether is an active solvent for cellulose acetate butyrate, nitrocellulose, epoxy resins, and other coating materials. Diethylene Glycol Monoethyl Ether solvent is used as a coalescent in latex paints and floor polishes, and as penetrating solvent in wood stains.
Diethylene Glycol Monoethyl Ether is produced via the O-alkylation of ethanol with two ethylene oxide units, followed by distillation. Diethylene Glycol Monoethyl Ether has a long history of safe use in food and personal-care products, and is used as an effective strong solubilizer in oral, topical, transdermal, and injectable human and veterinary pharmaceutical products.

Diethylene Glycol Monoethyl Ether has been used as a pharmaceutical solvent for many years under the trade name transcutol. Diethylene Glycol Monoethyl Ether, a hydroalcoholic solvent, is gaining interest as a penetration/permeation enhancer, solubilizer, and surfactant for drug delivery systems. The physicochemical properties of Diethylene Glycol Monoethyl Ether, the solubility data for drugs in Diethylene Glycol Monoethyl Ether or DEGEE -water mixtures, and the applications of Diethylene Glycol Monoethyl Ether in the solubilization of poorly water-soluble drugs are summarized in this review. Diethylene Glycol Monoethyl Ether has low setting point and low viscocity at low temperature so Diethylene Glycol Monoethyl Ether is used in manufacturing brake fluid.

IUPAC NAME:
2-(2-ethoxyethoxy)ethanol; Diglycol monoethyl ether;1-Hydroxy-3,6-dioxaoctane; 3,6Dioxa-1-octanol; Ethanol, 2,2′-oxybis-, monoethyl ether 

TRADE NAME:
O-ETHYLDIGOL; POLY-SOLV; POLY-SOLV DE; SOLVOLSOL; TRANSCUTOL; APV; CARBITOL; CELLOSOLVE; CARBITOL SOLVENT; CARBITOL SOLVENT LOW; DIOXITOL; DOWANO;      DOWANOL DE; EKTASOLVE DE;

OTHER NAME:
112-34-5; 111-77-3; 18068-06-9; 34455-29-3; 31160-64-2; 7646-67-5; 2532-49-2; 299-35-4;         1489-53-8; 42518-06-9; 10060-13-6; 77998-33-5; 1545739; 16774-56-4; 13586-38-4 13587-26-3

Diethylene Glycol Monoethyl Ether is used as a flow and gloss promoter in paint industries, in production of printing ink and as a cleaner in offset printing. Also used in textile as a solvent for dyestuff in the printing and dying of fiber & fabrics, in the production & wood preservaties.The global Diethylene Glycol Monoethyl Ether market size is projected to reach USD 538.8 million by 2025, expanding at a CAGR of 5.3%, according to a new report by Grand View Research, Inc. Increasing penetration of the product in floor polish and paints, coatings, and inks application is expected to drive the industry over the coming years.

Rising preference of Diethylene Glycol Monoethyl Ether market for manufacturing water-based coatings is a major factor contributing to the growth of the overall market for Diethylene Glycol Monoethyl Ether. Moreover, there is growing use of the product in formulation of variety of cleaning agents for industrial, household, and institutional cleaners. This factor has positively affected the product demand in cleaning agents. Asia Pacific and Eastern Europe are characterized by rapid urbanization, which is anticipated to propel the demand for residential, commercial, and industrial construction, thereby positively affecting the market for Diethylene Glycol Monoethyl Ether.
Floor polish application was the largest consumer of the product owing to its excellent solvent properties and accounted for 35.4% of total market size, in terms of volume, in 2018 .

The paints, coatings, and inks segment is expected to exhibit highest growth rate of 5.5%, in terms of revenue, over the forecast period on account of growing demand of the product in water based and solvent based paints High absorbency characteristic of Diethylene Glycol Monoethyl Ether market is anticipated to increase its demand as a chemical intermediate in variety of chemical blending processes Asia Pacific dominated the industry with a volume share of 54.1% in 2018 Europe is expected to witness a CAGR of 5.2%, in terms of revenue, from 2019 to 2025 due to the presence of major personal care product manufacturing companies, particularly in U.K., France, and Germany and high investment in production of innovative and effective personal care products.

The product is majorly used in skin treatment formulations in the form of topical creams or gels. Diethylene Glycol Monoethyl Ether is considered to be a safe and tolerable pharmaceutical-grade glycol ether when used at 99.9% purity. Diethylene Glycol Monoethyl Ether also acts as an intracutaneous depot for multiple drugs to reach different layers of the skin. The solvent is massively gaining demand in dermatology sector as Diethylene Glycol Monoethyl Ether has the ability to penetrate through the eisoderm of the skin and aid in healing the root cause. Owing to these factors, the product is anticipated to witness high growth in pharmaceutical and personal care application in near future. Ethylene oxide, which is precursor in manufacturing of Diethylene Glycol Monoethyl Ether, is highly regulated by multiple regulatory authorities such as U.S. EPA.

These regulations impact the production and industrial consumption of ethylene oxide, thus affecting the entire manufacturing cycle of ethylene oxide-based products. Currently, U.S. is one of the major producers of ethylene oxide owing to abundant availability of feedstock. However, increased restrictions on ethylene oxide plants are anticipated to hinder its production, which, in turn, is expected to have a negative impact on Diethylene Glycol Monoethyl Ether manufacturers.The solvent Diethylene Glycol Monoethyl Ether is currently used in over 500 cosmetic products and has enabled the formulation of a topical 5% dapsone gel for the treatment of acne.

Diethylene Glycol Monoethyl Ether is anticipated that this common cosmetic ingredient will be a component in numerous future prescription topical products approved for the US market. Dermatologists are already treating patients that apply products containing 5–40% of this solvent multiple times each day.The global Diethylene Glycol Monoethyl Ether market size was estimated at USD 374.9 million in 2018 and is expected to witness a CAGR of 5.3% from 2019 to 2025. The consumption of Diethylene Glycol Monoethyl Ether is dominated by its application in floor polish and paints, coatings, and inks owing to its superior properties as a solvent.

Rising adoption of Diethylene Glycol Monoethyl Ether as a coalescing agent in production of water-based coatings is a major factor driving the industry. There is an ascending demand for waterborne coatings in architectural and industrial sectors owing to their environment-friendly nature, which is expected to positively influence the demand for Diethylene Glycol Monoethyl Ether market.
There has been a shift in preference toward coatings with low volatile organic compound (VOC) emissions and non-hazardous nature from automotive, packaging, and construction industries over the past few years. This has facilitated utilization of waterborne coatings in numerous end-use industries.

This factor is anticipated to benefit the demand of Diethylene Glycol Monoethyl Ether as a solvent in water-based coatings.Diethylene Glycol Monoethyl Ether  is an important intermediate product for manufacturing solvents, plastic, and surfactants. In addition, it is a raw material used for the chemical production of Diethylene Glycol Monoethyl Ether. Suppliers of ethylene oxide are major petrochemical companies such as Royal Dutch Shell, Huntsman International LLC, Reliance Industries Limited, and China National Petroleum Corporation. Given their strong capital investment capacity, these companies are focusing on forward integration across the market value chain by developing new production technologies for glycol ethers.

Diethylene Glycol Monoethyl Ether market has gained acceptance by major regulatory bodies such as the U.S. Food and Drug Association (FDA) and the European Commission for its usage as an additive in topical products. Aczone (dapsone) gel is one of the products containing Diethylene Glycol Monoethyl Ether and is commonly prescribed by dermatologists for acne treatment. Furthermore, the product is highly water soluble and is likely to gain wider acceptance in the production of poorly water-soluble drugs. In the pharmaceutical industry, Diethylene Glycol Monoethyl Ether is suitable for the production of topical, transdermal, and injectable products.

Floor polish application dominated the Diethylene Glycol Monoethyl Ether market in 2018 and accounted for over 30% of the global volume. Diethylene Glycol Monoethyl Ether is known for its multifunctional properties to clean stains and add a glossy finish, especially on wooden flooring, which has resulted in a strong demand for the product.Paints, coatings, and inks is the second-largest application for the product and the segment is anticipated to exhibit a CAGR of 5.5%, in terms of revenue. This growth can be attributed to the biodegradable property of the Diethylene Glycol Monoethyl Ether-based paints and coatings. They are highly miscible in water and do not have any adverse effects on human health as well as the environment, which is expected to aid the product demand over the coming years.

The product is used as a solvent in the manufacturing of industrial chemicals. Diethylene Glycol Monoethyl Ether has gained preference as a chemical intermediate due to its compatibility with other chemicals. In the pharmaceutical and personal care sector, Diethylene Glycol Monoethyl Ether is commonly termed as Transcutol. Diethylene Glycol Monoethyl Ether is majorly used in skin treatment formulations in the form of topical creams or gels. The product is considered to be a safe and tolerable pharmaceutical-grade glycol ether when used at 99.9% purity.Diethylene Glycol Monoethyl Ether is used in the formulation of various cosmeceutical products as it has skin treatment properties.

Diethylene Glycol Monoethyl Ether is particularly gaining importance in antimicrobial soaps, antiperspirants, nail polish removers, fragrances, hair dyes, and in products for treating acne, marks, and scars owing to its super solubilizing and efficacy boosting properties. Significantly ascending demand for anti-acne products can be attributed to various factors such as prevalence of hormone related diseases and unhealthy lifestyles and inappropriate eating habits of consumers. Furthermore, the product is used in sunscreens and BB creams to enhance the properties of protective ingredients.Diethylene Glycol Monoethyl Ether, is a product of Ethylene Oxide and Ethanol. Diethylene Glycol Monoethyl Ether is chemically known as a Ethyl Diglycol, 2-hydroxy-2-ethoxy-diethyl ether. Diethylene Glycol Monoethyl Ether is an excellent solvent for the various resins & paste etc.

Diethylene Glycol Monoethyl Ether has low setting point and low viscocity at low temperature so it is used in manufacturing Brake Fluid. Ethyl Diglycol is used as a flow and gloss promoter in paint industries. The extendability of solution has also increased. Ethyl Carbitol is used in production of printing ink and as a cleaner in offset printing.Diethylene Glycol Monoethyl Ether is used in textile as a solvent for dyestuff in the printing and dying of fiber & fabrics. Ethyl Diglycol prevents the gel formation in liquid detergent and cleaner formulation. Diethylene Glycol Monoethyl Ether is also used a solubilizer in drilling and cutting coolants. Ethyl Diglycol is used in the production & formulation of pesticides & wood preservaties. Due to its low volatility property Diethylene Glycol Monoethyl Ether is used in Indian & ink ball point pastes. Diethylene Glycol Monoethyl Ether is also used in cosmetic & perfumary industry as a solvent. Ethyl diglycol (Ethyl Carbitol) does not attack rubber.

Diethylene Glycol Monoethyl Ether is ideal for use in topical and transdermal applications to enhance the permeation of poorly water-soluble API’s through various layers of the skin, thereby improving drug delivery. 2-(2-Ethoxyethoxy)ethanol, also known under many trade names, is the organic compound with the formula CH3CH2OCH2CH2OCH2CH2OH. Diethylene Glycol Monoethyl Ether is a colorless liquid. Diethylene Glycol Monoethyl Ether is a popular solvent for commercial applications. Diethylene Glycol Monoethyl Ether is produced by the ethoxylation of ethanol.Diethylene Glycol Monoethyl Ether is a solvent for dyes, nitrocellulose, paints, inks, and resins.

Diethylene Glycol Monoethyl Ether is a component of wood stains for wood, for setting the twist and conditioning yarns and cloth, in textile printing, textile soaps, lacquers, penetration enhancer in cosmetics, drying varnishes and enamels, and brake fluids. Diethylene Glycol Monoethyl Ether used to determine the saponification values of oils and as a neutral solvent for mineral oil-soap and mineral oil-sulfated oil mixtures (giving fine dispersions in water) DE Solvent Diethylene Glycol Monoethyl Ether is a very polar, slow evaporating, water miscible solvent with a low odor. Diethylene Glycol Monoethyl Ether is an active solvent for cellulose acetate butyrate, nitrocellulose, epoxy resins, and other coating materials.

Diethylene Glycol Monoethyl Ether is a type of glycol ether and is sold by under the tradename CARBITOLTM solvent. Diethylene Glycol Monoethyl Ether is an ethylene-series or E-series glycol ether that is an important component in wood stains and industrial cleaners. Textile printing and dyeing processes also use Diethylene Glycol Monoethyl Ether.Diethylene Glycol Monoethyl Ether has a high boiling point and low vapor pressure. Diethylene Glycol Monoethyl Ether is stable under recommended storage conditions and readily biodegradable. See Physical Hazard Information. Global industry capacity for E-series glycol ethers, including Diethylene Glycol Monoethyl Ether, was 952 thousand metric tons (2,098 million pounds). U.S. consumption of glycol ethers was 309 metric tons (682 million pounds). Has production facilities in the following U.S. locations; Midland, Michigan; Hahnville and Plaquemine, Louisiana; and Seadrift, Texas also has production facilities in San Lorenzo, Argentina and Stade, Germany.

Ethylene glycol monoethers Diethylene Glycol Monoethyl Ether are produced by reacting ethylene oxide with anhydrous (dry) alcohol (usually methyl, ethyl or butyl alcohol). Ethanol is used for Diethylene Glycol Monoethyl Ether  production.Diethylene Glycol Monoethyl Ether is a combustible liquid and is stable under recommended conditions. Storage containers made from carbon steel, stainless steel or phenolic-lined steel are recommended. Diethylene Glycol Monoethyl Ether should not be stored in containers made from aluminum, copper, galvanized iron or galvanized steel.Contact with strong acids, strong bases and strong oxidizers should also be avoided. Diethylene Glycol Monoethyl Ether should not be distilled to dryness because it can form peroxides that are unstable.Diethylene Glycol Monoethyl Ether can oxidize at elevated temperatures. Thermal decomposition products can include and are not limited to, aldehydes, ketones and organic acids.

Spills of glycol ethers, including Diethylene Glycol Monoethyl Ether, on hot fibrous insulations may lead to lowering of the autoignition temperatures possibly resulting in spontaneous combustion. Diethylene Glycol Monoethyl Ether is a combustible liquid and is stable under recommended conditions. Storage containers made from carbon steel, stainless steel or phenolic-lined steel are recommended. Diethylene Glycol Monoethyl Ether  should not be stored in containers made from aluminum, copper, galvanized iron or galvanized steel.Contact with strong acids, strong bases and strong oxidizers should also be avoided. Diethylene Glycol Monoethyl Ether  should not be distilled to dryness because it can form peroxides that are unstable. Diethylene Glycol Monoethyl Ether can oxidize at elevated temperatures. Thermal decomposition products can include and are not limited to; aldehydes, ketones and organic acids.Spills of glycol ethers, including Diethylene Glycol Monoethyl Ether, on hot fibrous insulations may lead to lowering of the autoignition temperatures possibly resulting in spontaneous combustion.

Diethylene Glycol Monoethyl Ether based glycol ether and glycol ether ester solvents have been used in the coatings industry for the past fifty years. Because of their excellent performance properties (evaporation rate, blush resistance, flow-out and leveling properties, solubility for coating resins, solvent activity, mild odor, good coupling ability, good solvent release) a complete line Diethylene Glycol Monoethyl Ether based solvents of various molecular weights has been developed. These glycol ether and glycol ether ester solvents have better solvent activity for coating resin than ester or ketone solvents in their evaporation rate range. The gloss, flow and leveling, and general performance properties of many coating systems are dependent on the use of these products in the coating formula. Because of the concern about the toxicity of certain Diethylene Glycol Monoethyl Ether based solvents, other products are being evaluated as replacements in coating formulas.

The first in a series of Diethylene Glycol Monoethyl Ether solvents based on glycol ethers. This colorless, odorless liquid is miscible with both water and most organic solvents. Diethylene Glycol Monoethyl Ether dissolves many oils, resins, and waxes. Diethylene Glycol Monoethyl Ether is used as a solvent for Diethylene Glycol Monoethyl Ether nitrate resins, spray lacquers, varnishes, and enamels. Diethylene Glycol Monoethyl Ether is also used in varnish removers and dry cleaning solutions. Other applications include use in dye baths, Leather finishing and as an emulsifier.

Diethylene Glycol Monoethyl Ether is a medium boiling, colorless stable liquid having a mild odor. Diethylene Glycol Monoethyl Ether is a completely miscible with water & organic liquid. Diethylene Glycol Monoethyl Ether is used as a solvent in nitrocellulose and cellulose Ether lacquers due to its pleasent odor. Diethylene Glycol Monoethyl Ether is also not slow down the drying time dispite its low volatility. The addition of small quantity of Diethylene Glycol Monoethyl Ether to alkyd resin and cellulose ether lacquers considerably reduce their viscosity & thus improves their brushability. Diethylene Glycol Monoethyl Ether is also used as an ingredient in cleaning agent and paints stippers. The Some vegetable Oils can be dispersed in water with the help of Diethylene Glycol Monoethyl Ether. 

Diethylene Glycol Monoethyl Ether tends to absorb water rapidly and therefore always mixed with Carbitol, methoxybutanol or Butanol, in order to prevent “blushing” of the lacquer film on drying. Cellulose lacquers containing Diethylene Glycol Monoethyl Ether are applied to stained wood, the solvent dissolves part of the stain out of the wood, giving slightly colored lacquer films. Diethylene Glycol Monoethyl Ether may also be used in the dying of leather. Diethylene Glycol Monoethyl Ether does not attack rubber.Diethylene Glycol Monoethyl Ether are used extensively as solvents because they tend to be quite soluble in both water and organic liquids. General uses include inks and dyes, enamels, paints and as cleaning agents in the dry-cleaning and glass-cleaning industries. The semiconductor industry also uses these compounds extensively as solvents and cleaning agents.

The Diethylene Glycol Monoethyl Ether are used widely as solvents for resins, lacquers, paints, varnishes, dyes and inks, as well as components of painting pastes, cleaning compounds, liquid soaps, cosmetics and hydraulic fluids. Propylene and butylene glycol ethers are valuable as dispersing agents and as solvents for lacquers, paints, resins, dyes, oils and greases.Diethylene Glycol Monoethyl Ether is a solvent in the lacquer, printing, metal and chemical industries. Diethylene Glycol Monoethyl Ether is also used for dyeing and printing in the textile industry and as a leather-finishing agent, an anti-icing additive for aviation fuels, and a component of varnish removers and cleansing solutions.

Diethylene Glycol Monoethyl Ether  and ethylene glycol monobutyl ether acetate function in industry as high-boiling solvents. Diethylene Glycol Monoethyl Ether is used for non-grain-raising wood stains, for brushing lacquers with mild odours, for stamp pad inks and for leather finishing. In the paint industry, Diethylene Glycol Monoethyl Ether is a coalescing agent for latex paint; and in the textile industry, Diethylene Glycol Monoethyl Ether is used for printing, textile soaps and dye pastes, as well as for setting the twist and conditioning yarns and cloth.The solvents  Diethylene Glycol Monoethyl Ether and diethylene glycol mono-n-butyl ether serve as diluents in hydraulic brake fluids. 2-Phenoxyethanol is a fixative for perfumes, cosmetics and soaps, a textile dye carrier and a solvent for cleaners, inks, germicides and pharmaceuticals. 2-Methoxyethanol is also a perfume fixative.

Diethylene Glycol Monoethyl Ether is used in the manufacture of photographic film, as a jet fuel anti-icing additive, as a solvent for resins used in the electronics industry, and as a leather-dyeing agent. 2-Methoxyethanol and propylene glycol methyl ether are useful for solvent-sealing of cellophane. Ethylene glycol mono-n-butyl ether is a solvent for protective coatings and for metal cleaners. Diethylene Glycol Monoethyl Ether is used in the textile industry to prevent spotting in printing or dyeing.Diethylene Glycol Monoethyl Ether is used in the manufacture of unsaturated polyester resins, polyurethanes and plasticizers. Diethylene Glycol Monoethyl Ether is a water-soluble liquid;  boiling point 245 C; soluble in many organic solvents. Diethylene Glycol Monoethyl Ether is used as a humectant in the tobacco industry and in the treatment of corks, glue, paper and cellophane. 

Diethylene Glycol Monoethyl Ether is derived as a co-product with ethylene glycol and triethylene glycol. The industry generally operates to maximize MEG production. Ethylene glycol is by far the largest volume of the glycol products in a variety of applications. Availability of Diethylene Glycol Monoethyl Ether will depend on demand for derivatives of the primary product, ethylene glycol, rather than on Diethylene Glycol Monoethyl Ether market requirements. Triethylene glycol, HO(C2H4O)3H, is a colourless, odourless, non-volatile, and hygroscopic liquid.

Diethylene Glycol Monoethyl Ether is characterised by two hydroxyl groups along with two ether linkages, which contribute to its high water solubility, hygroscopicity, solvent properties and reactivity with many organic compounds. Diethylene Glycol Monoethyl Ether is used in the synthesis of morpholine and 1,4-dioxane. TEG is displacing Diethylene Glycol Monoethyl Ether in many of these applications on account of its lower toxicity. Diethylene Glycol Monoethyl Ether  finds use as a vinyl plasticizer, as an intermediate in the manufacture of polyester resins and polyols, and as a solvent in many miscellaneous applications. 

Diethylene Glycol Monoethyl Ether is derived as a coproduct in the manufacture of ethylene glycol from ethylene oxide, and from "on-purpose" Diethylene Glycol Monoethyl Ether production using Diethylene Glycol Monoethyl Ether. Some capacities are based on total capacity for ethylene glycols. The main uses for Diethylene Glycol Monoethyl Ether  depend upon its hygroscopic properties. Air conditioning systems use Diethylene Glycol Monoethyl Ether as dehumidifiers and, when volatilized, as an air disinfectant for bacteria and virus control. Diethylene Glycol Monoethyl Ether, having high boiling point and affinity for water, are employed as liquid desiccant for the dehydration of natural gas.

The dehydration means the removal of water vapor in refinery tower so that dry hydrocarbon gases can exit from the top of the tower. There are wide range of glycol ethers which have bifunctional nature of ether and alcohol. cellosolves are monoether derivatives of ethylene glycol. They are excellent solvents, having solvent properties of both ethers and alcohols. Diethylene Glycol Monoethyl Ether, with the combination of ether, alcohol and hydrocarbon chain in one molecule, provide versatile solvency characteristics with both polar and non-polar properties. The chemical structure of long hydrocarbon chain resist to solubility in water, while ether or alcohol groups introduce the promoted hydrophilic solubility performance. This surfactant-like structure provides the compatibility between water and a number of organic solvents, and the ability to couple unlike phases. 

Diethylene Glycol Monoethyl Ether are characterized by their wide range of hydrophilic/hydrophobic balances. glycol ethers are used as diluents and levelling agents in the manufacture of paints and baking finishes. Diethylene Glycol Monoethyl Ether is used in the manufacture of nitrocellulose and combination lacquers. They are used as an additive in brake fluid. They are formulated for dying textiles and leathers and for insecticides and herbicides. They provides performance in cleaners products with oil-water dispersions. They are used in printing industries as they have a slow evaporation rate. They are used as a fixative for perfumes, germicides, bactericides, insect repellents and antiseptic. They are used as an additive for jet fuel to prevent ice buildup. Thje term of cellosolve refers to Diethylene Glycol Monoethyl Ether or a group of glycol ether solvent as below. 

The term of glyme refers to glycol dimethyl ether. Monoglyme, diglyme, triglyme are ethylene glycol dimethyl ether, Diethylene Glycol Monoethyl Ether dimethyl ether, and triethylene glycol dimethyl ether respectively. Ethylene glycol dimethyl ether is readily soluble in water. Glymes, dimethyl ethers, have two terminal methyl groups which offer stability and high solvency. They are used as a higher boiling alternative to diethyl ether or THF. Glyme forms chelate and are useful as bidentate ligands. They are useful as solubilizers and phase transfer catalysts. Glymes offer the property required as an inert reaction medium chemical reaction due to their low chemical reactivity. They are suitable particularly for organometallic and polymerization reactions.

Glycol ethers which contain hydroxyl group are also useful chemical intermediate. The hydroxyl group will undergo reaction with aldehydes (or ketones) to produce hemiacetals (or acetals), with epoxides to produce polyether alcohols, with halogenating agents to produce alkoxy alkyl halides, with carboxylic acid compounds or inorganic acids to produce a number of esters.Diethylene Glycol Monoethyl Ether, polyethylene glycol is a polyether compound, meaning that it has many ether groups. The difference between ethylene glycol and Diethylene Glycol Monoethyl Ether is that an ethylene glycol molecule is an individual molecule whereas Diethylene Glycol Monoethyl Ether molecule is formed by the combination of two ethylene glycol molecules via an ether bond.

The solvent Diethylene Glycol Monoethyl Ether is currently used in over 500 cosmetic products and has enabled the formulation of a topical 5% dapsone gel for the treatment of acne. Diethylene Glycol Monoethyl Ether is anticipated that this common cosmetic ingredient will be a component in numerous future prescription topical products approved for the US market. Dermatologists are already treating patients that apply products containing 5-40% of this solvent multiple times each day. To provide dermatologists a review of this solvent's safety and tolerance in addition to describing how.

Diethylene Glycol Monoethyl Ether interacts with the stratum corneum, sebum, and resident microflora. To critically review technical and patent literature that provides insight into this novel solvent. Diethylene Glycol Monoethyl Ether when used in a 99.9+% pure pharmaceutical grade is safe and well tolerated. Up to half of the applied solvent crosses the skin's barrier and becomes systemic. For certain drug actives, this solvent provides for an intracutaneous depot. This solvent has not demonstrated any inherent antimicrobial properties but was found to be mildly inhibitory toward Propionibacterium acnes. This safe, well-tolerated solvent is already used in many cosmetics and will become an ingredient in an increasing number of prescription products. Its ability to modify the skin delivery of actives .

Diethylene Glycol Monoethyl Ether is formulated with (or formulation components that are applied just shortly before or after) make Diethylene Glycol Monoethyl Ether important for dermatologists to have an understanding of this emerging solvent.
Diethylene Glycol Monoethyl Ether is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. Diethylene Glycol Monoethyl Ether is miscible in water, alcohol, ether, acetone, and ethylene glycol. Diethylene Glycol Monoethyl Ether is a widely used solvent. Diethylene Glycol Monoethyl Ether can be a contaminant in consumer products; this has resulted in numerous epidemics of poisoning since the early 20th century.

Diethylene Glycol Monoethyl Ether is produced by the partial hydrolysis of ethylene oxide. Depending on the conditions, varying amounts of  and related glycols are produced. The resulting product is two ethylene glycol molecules joined by an ether bond.
"Diethylene Glycol Monoethyl Ether is derived as a co-product with ethylene glycol and triethylene glycol. The industry generally operates to maximize MEG production. Diethylene Glycol Monoethyl Ether is by far the largest volume of the glycol products in a variety of applications. Availability of  will depend on demand for derivatives of the primary product, ethylene glycol, rather than on  market requirements."

Diethylene Glycol Monoethyl Ether is used in the manufacture of saturated and unsaturated polyester resins, polyurethanes, and plasticizers.  is used as a building block in organic synthesis, e.g. of morpholine and 1,4-dioxane.Diethylene Glycol Monoethyl Ether is a solvent for nitrocellulose, resins, dyes, oils, and other organic compounds. Diethylene Glycol Monoethyl Ether is a humectant for tobacco, cork, printing ink, and glue. Diethylene Glycol Monoethyl Ether is also a component in brake fluid, lubricants, wallpaper strippers, artificial fog and haze solutions, and heating/cooking fuel. In personal care products (e.g. skin cream and lotions, deodorants), is often replaced by selected.

Diethylene Glycol Monoethyl Ether. A dilute solution of Diethylene Glycol Monoethyl Ether can also be used as a cryoprotectant; however, ethylene glycol is much more commonly used. Most ethylene glycol antifreeze contains a few percent Diethylene Glycol Monoethyl Ether, present as an byproduct of ethylene glycol production.Production of Diethylene Glycol Monoethyl Ether is generally based on the demand for, and production of, monoethylene glycol as it isa by-product of this production process.  The process consists of the oxidation of ethylene at a high temperature in the presence of a silver oxide catalyst.  The ethylene oxide is then hydrated to yield Diethylene Glycol Monoethyl Ether with monoethylene glycol and triethylene glycol as co-products.

The chemical industry tries to maximise the production of monoethylene glycol in this process but Diethylene Glycol Monoethyl Ether is a very useful by-product. Diethylene Glycol Monoethyl Ether has a variety of uses in industry. The tobacco industry makes use of its hygroscopic properties and usesDiethylene Glycol Monoethyl Ether as humectant in tobacco production.  This same property also makesDiethylene Glycol Monoethyl Ether useful in the treatment of paper, cork, glue, and cellophane andDiethylene Glycol Monoethyl Ether is utilised as a dehydrant in the natural gas industry whereDiethylene Glycol Monoethyl Ether removes the water from the gas pipelines.

Diethylene Glycol Monoethyl Ether is also used as a chemical intermediate in the manufacture of unsaturated polyester resins, plasticisers, acrylate and methacrylate resins, and urethanes.  In the U.S. and Western Europe 51% of  is consumed in this way. 
However, in Japan Diethylene Glycol Monoethyl Ether is most utilised as a cement grinding aid.  Diethylene Glycol Monoethyl Ether can also be used in petroleum solvent extraction, and can be found in printing ink, and drywall joint compound. Di ethylene glycol is now being displaced by tri ethylene glycol in some of its applications as the lower toxicity of Diethylene Glycol Monoethyl Ether makes it more appealing to manufacturers. Diethylene Glycol Monoethyl Ether is a diatomic alcohol, a colorless or yellowish transparent liquid. Diethylene Glycol Monoethyl Ether is used in the chemical industry (organic synthesis, production of polyurethanes and resins from unsaturated complex esters, production of plasticisers), gas production (as a drying agent for hydrate plug removal), oil processing (as a solvent used to extract aromatic hydrocarbons).

Diethylene Glycol Monoethyl Ether used as a humectant (tobacco, casein, synthetic sponges, composition corks, glues, gelatin, and paper products), a dehydrating agent (plasticizers, surfactants, and natural gas), a lubricating and finishing agent (wool, worsted, cotton, rayon, and silk), a solvent for vat dyes, an intermediate (triethylene glycol and Diethylene Glycol Monoethyl Ether dinitrate), a petroleum extraction solvent, and a monomer (unsaturated polyester resins and polyols for polyurethane); Diethylene Glycol Monoethyl Ether also used in lacquers, cosmetics, antifreeze solutions for sprinkler systems; water seals for gas tanks, brake fluids, lubricants, mold release agents, and inks; Diethylene Glycol Monoethyl Ether used mainly to produce unsaturated polyester resins, polyols, and polyurethanes.

Diethylene Glycol Monoethyl Ether is soluble both in water and in many organic compounds and has hygroscopic properties which makes Diethylene Glycol Monoethyl Ether a useful industrial chemical. Demand of Diethylene Glycol Monoethyl Ether is based on the demand for monoethylene glycol.  The process consists of the oxidation of ethylene at a high temperature in the presence of a silver oxide catalyst.  The ethylene oxide is then hydrated to yield Diethylene Glycol Monoethyl Ether with monoethylene glycol and triethylene glycol as co-products. Diethylene Glycol Monoethyl Ether is utilized in the industry of paper, tobacco, glue, cellophane and natural gas industry due of its hygroscopic properties.Diethylene Glycol Monoethyl Ether is also used as a chemical intermediate in the manufacture of unsaturated polyester resins, plasticisers, acrylate and methacrylate resins, and urethanes. Diethylene Glycol Monoethyl Ether  can also be used as a cement grinding aid, in solvent extraction, and in printing ink.

Diethylene Glycol Monoethyl Ether is now being displaced by tri ethylene glycol as the lower toxicity of tri ethylene glycol. Diethylene Glycol Monoethyl Ether is clear, colorless and odorless liquid with a slightly sweetish taste, hygroscopic, with a low volatileness. Diethylene Glycol Monoethyl Ether is an excellent solvent for water-insoluble chemical compounds and drugs. Diethylene Glycol Monoethyl Ether is a widely used solvent, making Diethylene Glycol Monoethyl Ether useful in cleaners, cement processing, heat transfer fluids and adhesives. Diethylene Glycol Monoethyl Ether is used in manufacturing of unsaturated polyester resins, polyurethanes, and plasticizers.

Diethylene Glycol Monoethyl Ether is a component in printing ink formulations and a plasticizing and lubricating agent for natural and synthetic fibers. Diethylene Glycol Monoethyl Ether is used among others to produce unsaturated polyester resins, thermoplastic polyurethanes and plastifiers, as an additive in producing glass and cement, furniture, shoe polishes, printing inks, plaster boards, emulsifiers and anti-freezes, beauty products, lubricants, brake fluids, wallpaper removers and as an agent heating up or cooling down the fuel.Diethylene Glycol Monoethyl Ether depend on demand for derivatives of the primary product, ethylene glycol, rather than on Diethylene Glycol Monoethyl Ether market requirements. Diethylene Glycol Monoethyl Ether is used in the manufacture of saturated and unsaturated polyester resins, polyurethanes, and plasticizers. Diethylene Glycol Monoethyl Ether is used as a building block in organic synthesis.

Diethylene Glycol Monoethyl Ether is a solvent for nitrocellulose, resins, dyes, oils, and other organic compounds. Diethylene Glycol Monoethyl Ether  is a humectant for tobacco, cork, printing ink, and glue. Diethylene Glycol Monoethyl Ether is also a component in brake fluid, lubricants, wallpaper strippers, artificial fog and haze solutions, and heating/cooking fuel. In personal care products (e.g. skin cream and lotions, deodorants), Diethylene Glycol Monoethyl Ether is often replaced by selected Diethylene Glycol Monoethyl Ether. A dilute solution of Diethylene Glycol Monoethyl Ether can also be used as a cryoprotectant; however, ethylene glycol is much more commonly used. Most ethylene glycol antifreeze contains a few percent Diethylene Glycol Monoethyl Ether, present as an byproduct of ethylene glycol production. Diethylene Glycol Monoethyl Ether is used in the production of unsaturated polyester resins, polyurethanes and plasticizers. 

Diethylene Glycol Monoethyl Ether is used as a solvent in dye ink and textile dyeing. Diethylene Glycol Monoethyl Ether is used in the tobacco industry as a moisture scavenger. Diethylene Glycol Monoethyl Ether is used as a snow spray on airplanes and railways. Diethylene Glycol Monoethyl Ether is used as a thinner in the glue industry. Diethylene Glycol Monoethyl Ether  is used as a selective solvent for aromatics in oil refining. Diethylene Glycol Monoethyl Ether is used as a solvent in printing in the textile industry and also Diethylene Glycol Monoethyl Ether is used as an auxiliary agent in the content of textile dyes. Diethylene Glycol Monoethyl Ether, is a colorless, sweet-tasting, odorless, toxic and hygroscopic liquid. Diethylene Glycol Monoethyl Ether is easily miscible in alcohol, water, ether and ethylene glycol.


 

 

 

 

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