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Diethylhexyl Sodium Sulfosuccinate is a white or almost white, waxlike, bitter tasting, plastic solid with a characteristic octanol-like odor.
Diethylhexyl Sodium Sulfosuccinate is hygroscopic and usually available in the form of pellets, flakes, or rolls of tissuethin material.
Diethylhexyl Sodium Sulfosuccinate is an anionic surfactant also known as docusate sodium, sodium dioctyl sulfosuccinate, or sodium bis(2-ethylhexyl) sulfosuccinate.
CAS Number: 577-11-7
Molecular Formula: C20H37O7S.Na
Molecular Weight: 445.57
EINECS Number: 209-406-4
Synonyms: Docusate sodium, Dioctyl sulfosuccinate sodium salt, Aerosol OT, Dioctyl sulfosuccinate sodium, Dioctylal, Diotilan, Disonate, Molatoc, Regutol, Velmol, Doxol, Nevax, Dialose, Doxinate, Soliwax, Colace, Molcer, Waxsol, Adekacol EC 8600, Mervamine, Clestol, Defilin, Molofac, Obston, Requtol, Docusate sodique, Modane Soft, Alcopol O, Sulfimel DOS, Manoxal OT, Aerosol AOT, Aerosol GPG, Wetaid SR, Laxinate 100, Sanmorin OT 70, Triton GR 7, Aerosol OT 70PG, Aerosol OT 75, Celanol DOS 65, Celanol DOS 75, Coloxyl, Comfolax, Coprola, Dioctyl, Dulcivac, Eurowet, Humifen WT 27G, Jamylene, Silace, Bloat treatment, Docusato sodico, Nikkol OTP 70, Aerosol A 501, Berol 478, Docusatum natricum, Empimin op70, Sanmorin ot 70n, Natrii dioctylsulfosuccinas, Airrol ct-1, Mackanate dos-70, Nikkol otp-75, Gemtex pa-70, Rapisol a 30, Triton gr-pg 70, Sodium dioctyl sulphosuccinate, Nissan rapisol a 30, DTXSID8022959, Ins no.480, Monawet mo 65-150, Dioctyl ester of sodium sulfosuccinic acid, docusato de sodio, Ins-480, Dioctyl ester of sodium sulfosuccinate, F05Q2T2JA0, Diethylhexyl Sodium Sulfosuccinate, CHEMAX DOSS/75E, NSC-760404, Bis(ethylhexyl) ester of sodium sulfosuccinic acid, CHEBI:4674, DTXCID102959, E 480, E-480, Correctol Stool Softener Laxative, Butanedioic acid, sulfo-, 1,4-bis(2-ethylhexyl) ester, sodium salt, DIOCTYL DISODIUM SULFOSUCCINATE, AEC DIETHYLHEXYL SODIUM SULFOSUCCINATE, 209-406-4, Promolaxin, Audinorm, Colistat, Dulcoease, Norgalax, natrii docusas, DocuSol, Colace Clear, Enemeez Kids, Clear ear, Docu Liquid, Single-Use, DocuSol Kids, Fletchers' enemette, CVS Stool Softener, Docusate Mini Enema, HEB Stool Softener, Laxa-basic 100, Clear Stool Softener, Docusol 100, ENEMEEZ, Winco Stool Softener, Gentle Stool softener, Kroger Stool Softener, Stool Softener Liquid, BLOAT RELEASE, STOOL SOFTNER, Docusate Sodium Liquid, PET-ENEMA, Topcare Stool Softener, DISPOSABLE ENEMA, DEH Na SS, DEH-Na-SS, Dulcolax Stool Softener, FELINE PET-EMA, PET-EMA, Phillips Stool Softener, RefChem:5774, H E B Stool Softener, Docusate Sodium 100mg, Docusate Sodium 250mg, Walgreens Stool Softener, basic care stool softener, CVS Health Stool Softener, betr remedies stool softener, Gentle Relief Stool Softner, Gentle Relief Stool Softnet, COLACE EXTRA STRENGTH, DQZATE STOOL SOFTENER, Dulcolax Pink Stool Softener, Good Neighbor Stool Softener, Dioctylsulphosuccinate, Sodium, exchange select stool softener, Quality Choice Stool Softener, Stool Softener Extra Strength, healthy mama MOVE IT ALONG, Dioctyl Sulfosuccinate, Sodium, Stool Softener Docusate Sodium, DOCUSATE SODIUM 50 MG, DOCUSATE SODIUM 100 mg, H E B Stool Softener laxative, Stool Softener Regular Strength, Topcare Stool Softener laxative, CVS Stool Softener Fruit Punch, GeriCare Docusate Sodium Liquid, CVS Health Stool Softener Clear, A06AA02, Non-Habit Forming Stool Softener, Preferred Stool Softener laxative, Kroger Stool Softener Fruit Punch, Sodium Sulfosuccinate, Diethylhexyl, Sulfosuccinate, Diethylhexyl Sodium, DOCUSATE SODIUM 100mg Two-Tone, Walgreens Stool Softener Fruit Punch, Good Neighbor Stool Softener laxative, Phillips Stool Softener Bulk Docusate, Quality Choice Stool Softener laxative, Stool Softener Laxative Extra Strength, DOCUSATE SODIUM, EXTRA STRENGTH, Dioctyl Sulfosuccinic Acid, Sodium Salt, Docusate Sodium-Stool Softener Laxative, DOK EXTRA STRENGTH STOOL SOFTENER, COLACE EXTRA STRENGTH STOOL SOFTNER, Docusate Sodium softgels 50mg (Dye Free), DOCUSATE SODIUM 50MG SOFTGEL (RED), EXTRA STRENGTH STOOL SOFTENER LAXATIVE, STOOL SOFTENER DOCUSATE SODIUM 50 MG, DOCUSATE SODIUM, EXTRA STRENGTH 250 MG, DOCUSATE SODIUM 100MG-docusate sodium capsule, liquid filled, Monoxol OT, NSC-7779, Rapisol, Sodium Bis(2-ethylhexyl)sulfosuccinate, Sodium Dioctylsulphosuccinate, Vatsol OT, 577-11-7, Diox, Manoxol OT, Docusate (Sodium), Docusate sodium salt, doss, Bis(2-ethylhexyl) sodium sulfosuccinate, Bis(2-ethylhexyl) sulfosuccinate sodium salt, Sodium 1,4-bis(2-ethylhexyl) sulfosuccinate, Sodium 1,4-bis((2-ethylhexyl)oxy)-1,4-dioxobutane-2-sulfonate, MFCD00012455, sodium 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonate, sodium docusate, SBO, Diomedicone, Complemix, Constonate, Dioctlyn, Diosuccin, Dulsivac, Laxinate, Sobital, Coprol, Diovac, Kosate, Softil, Revac, Alphasol OT, Aerosol OT-A, Triton GR-5, DESS, Monawet MD 70E, Solusol-75%, Alkasurf SS-O 75, Solusol-100%, Nekal WT-27, Docolace, Docuprene, Geriplex, sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate, Unilax, Dioctyl sodium sulfosuccinate (JAN), AOT, Dialose Plus, Tex-Wet 1001, Senokot S, Correctol Caplets, Correctol Tablets, Senokap DSS, D-S-S, Doc Q Lace, CAS-577-11-7, DIOCTYL SODIUM SULFOSUCCINATE [JAN], Correctol Extra Gentle Tablets, Sodium bis(2-ethylhexyl) sulfosuccinate, Docusate sodique [INN-French], Docusato sodico [INN-Spanish], Docusatum natricum [INN-Latin], HSDB 3065, 2-Ethylhexyl sulfosuccinate sodium, NCGC00164140-03, EINECS 209-406-4, SV 102, Bis(2-ethylhexyl)sodium sulfosuccinate, C20H37NaO7S, Di-(2-ethylhexyl) sodium sulfosuccinate, Sodium di-(2-ethylhexyl) sulfosuccinate, Dioctyl sodium sulphosuccinat, UNII-F05Q2T2JA0, Prenexa, Purgasol, Vinacol, Bis(2-ethylhexyl) S-sodium sulfosuccinate, AI3-00239, Sodium 1,4-bis(2-ethylhexyl)sulfosuccinate, 1,4-Bis(2-ethylhexyl) sodium sulfosuccinate, Sodium sulfodi-(2-ethylhexyl)-sulfosuccinate, Docusate sodium; Sodium 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonate, Folca[s care pme, Folcal DHA, Di(2-ethylhexyl)sulfosuccinic acid, sodium salt, Aerosol OT(AOT), Bis-2-ethylhexylester sulfojantaranu sodneho [Czech], Colace (TN), Docusate sodium CRS, Sodium di(2-ethylhexyl)sulfosuccinate, Sulfosuccinic acid, bis(2-ethylhexyl)ester sodium salt, Aerosol OT (AOT), Docusate sodium [USAN:USP:INN:BAN], Docusate Sodium, DDS, Sol sodowej sulfobursztynianu dwu-2-etyloheksylowego [Polish], Docusate sodium (USP), Bis-2-ethylhexylester sulfojantaranu sodneho, Succinic acid, sulfo-, 1,4-bis(2-ethylhexyl) ester, sodium salt, NCGC00183136-01, EC 209-406-4, SCHEMBL4113, DOCUSATE SODIUM [II], DOCUSATE SODIUM [MI], MLS004773938, DOCUSATE SODIUM [INN], 1,4-Bis(2-ethylhexyl)sulfobutanedioate, sodium salt, Docusate (Sodium) (Standard), Sol sodowej sulfobursztynianu dwu-2-etyloheksylowego, DOCUSATE SODIUM [HSDB], DOCUSATE SODIUM [USAN], Docusate sodium [EP monograph], orb1224610, orb1310159, DOCUSATE SODIUM [VANDF], Aerosol OT pound AOT pound(c), CHEMBL1905872, DOCUSATE SODIUM [MART.], HY-B1268R, DOCUSATE SODIUM [USP-RS], DOCUSATE SODIUM [WHO-DD], Sulfosuccinic acid, di-(2-ethylhexyl) ester, sodium salt, dioctyl sulphosuccinate sodium salt, HMS3264P07, HMS3885B10, HMS5083D17, HY-B1268, Sodium dioctyl sulfosuccinate (INN), Tox21_112087, Tox21_113469, Tox21_201342, Tox21_300496, EBC-98058, MSK161884, s4588, AKOS015901806, DOCUSATE SODIUM [USP IMPURITY], CCG-213234, CS-4813, DOCUSATE SODIUM [USP MONOGRAPH], FD34388, MSK161884-100A, NSC 760404, Docusate sodium salt, BioXtra, >=99%, Dioctyl sulfosuccinate sodium salt, 96%, MSK161884-1000A, NCGC00164140-01, NCGC00254414-01, NCGC00258894-01, AS-13347, E480, SMR001595510, DIOCTYL SODIUM SULFOSUCCINATE [FCC], Bis(2-ethylhexyl) sulfosuccinatesodium salt, Dioctyl sulfosuccinate sodium salt, >=97%, NS00074370, T0929, D00305, Docusate sodium salt, p.a., 99.0-100.5%, E77584, SBI-0653437.0001, Docusate sodium salt, purum, >=96.0% (TLC), Docusate sodium salt, BioUltra, >=99.0% (TLC), Docusate sodium, meets USP testing specifications, F981883, Q2815334, Sulfosuccinic acid bis(2-ethylhexyl) ester sodium salt, F8880-5559, Docusate sodium, British Pharmacopoeia (BP) Reference Standard, Docusate sodium, European Pharmacopoeia (EP) Reference Standard, sodium;1,4-bis(2-ethylhexoxy)-1,4-dioxo-butane-2-sulfonate, Dioctyl sodium sulfosuccinate Solution in Acetonitrile, 1000ug/mL, Dioctyl sodium sulfosuccinate Solution in Acetonitrile, 100ug/mL, Docusate sodium, United States Pharmacopeia (USP) Reference Standard, Docusate sodium salt; Sulfosuccinic acid bis(2-ethylhexyl) ester sodium salt, Butanedioic acid, 2-sulfo-, 1,4-bis(2-ethylhexyl) ester, sodium salt (1:1) doctesodium;doxinate;doxol;dulsivac;duosol;humifenwt27g;konlax;kosate
Diethylhexyl Sodium Sulfosuccinate is the sodium salt of the diester formed from 2-ethylhexyl alcohol and sulfosuccinic acid, with the chemical formula C20H37NaO7S and CAS number 577-11-7.
Diethylhexyl Sodium Sulfosuccinate groups together with a sulfosuccinate group, allowing it to reduce surface and interfacial tension and interact effectively with both oily and aqueous phases.
Diethylhexyl Sodium Sulfosuccinate is commonly identified by the INCI name DIETHYLHEXYL SODIUM SULFOSUCCINATE and has the EC number 209-406-4.
Diethylhexyl Sodium Sulfosuccinate is generally supplied as a surfactant raw material whose physical form can vary with purity, concentration, solvent system, and commercial grade, ranging from waxy solids to liquids or concentrated solutions.
Commercial grades are used primarily for their emulsifying, wetting, dispersing, cleansing, and hydrotropic properties rather than as a simple foaming ingredient.
Diethylhexyl Sodium Sulfosuccinates molecular structure gives particularly strong wetting characteristics, allowing liquids to spread more readily across surfaces and helping dispersed materials become more uniformly distributed.
Diethylhexyl Sodium Sulfosuccinate can also facilitate the formation and stabilization of emulsions by reducing the interfacial tension between otherwise poorly compatible phases such as oil and water.
Diethylhexyl Sodium Sulfosuccinates have made it useful across cosmetic, pharmaceutical, textile, detergent, plastics, construction, and other formulation-oriented applications.
In cosmetic formulations, Diethylhexyl Sodium Sulfosuccinate can function as a cleansing agent, emulsifier, hydrotrope, and general surfactant.
Diethylhexyl Sodium Sulfosuccinate can improve the dispersion or solubilization of selected formulation components and may contribute to foam formation, particularly when combined with other surfactants.
The Cosmetic Ingredient Review has assessed Diethylhexyl Sodium Sulfosuccinate as part of the dialkyl sulfosuccinate group and concluded that these ingredients are safe for cosmetic use under the assessed conditions when formulated to be non-irritating.
Diethylhexyl Sodium Sulfosuccinate is also known by the historical name dioctyl sodium sulfosuccinate, although the ethylhexyl terminology more accurately describes the 2-ethylhexyl groups present in its structure.
The abbreviation DOSS is frequently encountered in technical literature, while Docusate Sodium is particularly common in pharmaceutical contexts.
Diethylhexyl Sodium Sulfosuccinate broad synonym range reflects its use across different industries and regulatory or technical naming systems.
Diethylhexyl Sodium Sulfosuccinate has a sulfosuccinate backbone in which both carboxylic acid groups are esterified with 2-ethylhexyl groups, while the sulfonate group remains ionized and is associated with sodium.
This arrangement gives the molecule a relatively large hydrophobic region together with a strongly polar ionic group, which is responsible for its surface-active behavior.
The compound is therefore able to accumulate at interfaces and modify interactions between water, oils, solids, and other formulation components.
The ester bonds in Diethylhexyl Sodium Sulfosuccinate are chemically significant because sulfosuccinate diesters can undergo hydrolysis, particularly under acidic conditions.
Hydrolysis can alter the composition and performance of the surfactant system, making pH and formulation conditions relevant when developing products containing the ingredient.
This is one reason commercial formulations are evaluated according to the specific grade, concentration, pH, and storage conditions rather than relying only on the identity of the pure compound.
Diethylhexyl Sodium Sulfosuccinate is also recognized as a multifunctional cosmetic ingredient rather than simply a cleansing surfactant.
Diethylhexyl Sodium Sulfosuccinate documented cosmetic functions include surfactant activity and related formulation roles, while its strong wetting properties can be useful when rapid spreading and contact with a surface are required.
The ingredient has been evaluated by the Cosmetic Ingredient Review as part of the dialkyl sulfosuccinate group, with safety conclusions dependent on formulations being prepared to avoid irritation.
The ingredient has also been used in pharmaceutical formulations under the name docusate sodium, where its surfactant properties are relevant to its function as a stool-softening agent.
This pharmaceutical identity is important because docusate sodium and cosmetic-grade Diethylhexyl Sodium Sulfosuccinate refer to the same chemical substance, while the applicable specifications and formulation requirements can differ according to the intended use.
Consequently, pharmaceutical, cosmetic, and industrial materials should be selected according to their individual quality specifications rather than assuming that every commercial grade is interchangeable.
Melting point: 173-179 °C (lit.)
Boiling point: 82.7 °C
Density: 1.1
Vapor pressure: 0 Pa at 25 °C
Storage temp.: Inert atmosphere, Room Temperature
Solubility: Methanol: 0.1 M at 20 °C, clear, colorless
Form: Waxy Solid
Color: White
Specific Gravity: 1.005
Percent volatile: 40
Water solubility: 1.5 g/100 mL (25 °C)
Sensitive: Hygroscopic
λmax: λ: 260 nm, Amax: 0.1; λ: 280 nm, Amax: 0.05
Merck: 14,3401
BRN: 4117588
Henry's Law Constant: 2.0 × 10⁶ mol/(m³Pa) at 25 °C, HSDB (2015)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions: SURFACTANT - HYDROTROPE; SURFACTANT - EMULSIFYING; SURFACTANT - CLEANSING; CLEANSING
Cosmetic Ingredient Review (CIR): Dioctyl sulfosuccinate sodium salt (577-11-7)
InChI: 1S/C20H38O7S.Na/c1-5-9-11-16(7-3)14-26-19(21)13-18(28(23,24)25)20(22)27-15-17(8-4)12-10-6-2;/h16-18H,5-15H2,1-4H3,(H,23,24,25);/q;+1/p-1
InChIKey: APSBXTVYXVQYAB-UHFFFAOYSA-M
SMILES: [Na+].CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S([O-])(=O)=O
LogP: 1.998 at 20 °C
Diethylhexyl Sodium Sulfosuccinate is stable in the solid state when stored at room temperature.
Diethylhexyl Sodium Sulfosuccinate aqueous solutions of docusate sodium between pH 1–10 are stable at room temperature.
However, at very low pH (<1) and very high pH (>10) docusate sodium solutions are subject to hydrolysis.
Diethylhexyl Sodium Sulfosuccinate is also notable because its structure gives it strong surface-active behavior while allowing it to function at relatively low concentrations in many formulations.
The two 2-ethylhexyl ester groups provide the hydrophobic portion of the molecule, while the sulfosuccinate group and sodium counterion provide the ionic, water-compatible portion.
This amphiphilic structure enables the ingredient to lower interfacial tension, improve wetting, and assist in the dispersion of substances that do not readily mix with water.
Diethylhexyl Sodium Sulfosuccinate is an anionic surfactant belonging to the dialkyl sulfosuccinate family.
Unlike ethoxylated sulfosuccinates such as Disodium Laureth Sulfosuccinate, Diethylhexyl Sodium Sulfosuccinate does not contain a polyethylene glycol chain in its basic structure.
Diethylhexyl Sodium Sulfosuccinate structural difference contributes to different physicochemical behavior and explains why the two ingredients should not be treated as interchangeable simply because both belong to the broader sulfosuccinate family.
Diethylhexyl Sodium Sulfosuccinate can be manufactured by forming the appropriate diester and subsequently introducing the sulfonate functionality using a sulfite or bisulfite-based process.
The resulting material is purified to meet specifications appropriate for its intended application, with purity, residual water, inorganic residue, and residual reaction intermediates being relevant quality parameters.
Pharmaceutical and food-related specifications can be considerably more stringent than those required for general industrial surfactant grades.
Diethylhexyl Sodium Sulfosuccinate has applications beyond conventional surfactant formulations because its wetting and interfacial properties can assist processes in which rapid contact between liquids and solid surfaces is required.
Diethylhexyl Sodium Sulfosuccinate has therefore been used as a wetting agent, emulsifying or dispersing aid, and surface-active component in different industrial and formulation systems.
Diethylhexyl Sodium Sulfosuccinate chemical behavior also makes it useful as a formulation aid where improved spreading or distribution of another ingredient is required.
Diethylhexyl Sodium Sulfosuccinate is particularly well known under the name Docusate Sodium in pharmaceutical applications.
In this context, its surfactant properties are used in oral formulations as a stool-softening agent, where the substance helps water and lipids interact with fecal material rather than acting primarily as a conventional bulk-forming laxative.
The pharmaceutical use of docusate is therefore distinct from its role as a cosmetic or industrial surfactant.
Diethylhexyl Sodium Sulfosuccinate regulatory and technical status can also vary substantially according to the application and product grade.
For example, the CIR assessment describes its established use in cosmetics, while pharmaceutical and food applications are subject to their own specifications and regulatory requirements.
Consequently, the identity of the chemical alone does not determine whether a particular commercial grade is suitable for a specific end use.
In cosmetic formulations, the ingredient has historically been reported in products such as makeup preparations, including eyebrow products.
The CIR review reported a maximum use concentration of 4.4% in eyebrow pencil formulations in the available use data, while also emphasizing that prolonged skin contact requires attention to potential irritation.
These historical use concentrations should not be interpreted as a universal recommended concentration for every cosmetic formulation because formulation type and regulatory requirements can differ.
Uses Of Diethylhexyl Sodium Sulfosuccinate:
Diethylhexyl Sodium Sulfosuccinate, used for the treatment of constipation, acting as a laxative or stool softener.
Also used in the synthesis of electrospun fibres for tailored and controlled antibiotic drug release.
Diethylhexyl Sodium Sulfosuccinate is a wetting and emulsifying agent that is slowly soluble in water, having a solubility of 1 g in 70 ml of water.
Diethylhexyl Sodium Sulfosuccinate functions as a wetting agent in fumaric acid-containing powdered fruit drinks to help the acid dissolve in water.
Diethylhexyl Sodium Sulfosuccinate is used as a stabilizing agent on gums at not more than 0.5% by weight of the gum.
Diethylhexyl Sodium Sulfosuccinate is used as a flavor potentiator in canned milk where it improves and maintains the flavor of the sterilized milk during storage.
Diethylhexyl Sodium Sulfosuccinate also functions as a processing aid in the manufacture of unrefined sugar.
It is also termed sodium dioctylsulfosuccinate.
Diethylhexyl Sodium Sulfosuccinate is widely used in cosmetic formulations as an anionic surfactant, emulsifier, wetting agent, and dispersing aid.
Diethylhexyl Sodium Sulfosuccinate can help combine or stabilize oil and water phases while also improving the spreading and distribution of other ingredients throughout a formulation.
Its relatively strong surface activity allows it to perform these functions at comparatively low concentrations in suitable formulations.
In facial cleansers, body washes, liquid soaps, and other cleansing products, Diethylhexyl Sodium Sulfosuccinate can contribute to the removal of oily and particulate impurities from the skin.
Diethylhexyl Sodium Sulfosuccinate can also improve wetting and help other surfactants interact more effectively with the skin and formulation ingredients.
Its use in cosmetics has been documented across numerous product categories, with the CIR review identifying it primarily as a surfactant.
The ingredient is also used in color cosmetics where its wetting and dispersing properties can help distribute pigments and other solid components.
Documented cosmetic applications include eyebrow pencil formulations, while commercial surfactant grades are also promoted for applications such as eye-contour pencils, nail varnishes, and hair sprays.
In these products, its role is mainly associated with improving dispersion, wetting, and formulation performance rather than providing the primary cosmetic effect itself.
Diethylhexyl Sodium Sulfosuccinate has important applications in the textile industry, particularly in wetting formulations used during fiber processing.
Diethylhexyl Sodium Sulfosuccinate can improve the penetration of aqueous treatment solutions into textile fibers and increase the effectiveness of washing processes, including the removal or application of sizing materials.
Its strong wetting action is especially useful where rapid and uniform contact between a liquid treatment and a hydrophobic textile surface is required.
Diethylhexyl Sodium Sulfosuccinate is used as a wetting additive in paints, coatings, adhesives, and varnishes.
By lowering interfacial tension, it helps liquid formulations spread more readily across substrates and can improve the contact between formulation components and solid surfaces.
Diethylhexyl Sodium Sulfosuccinate can also be incorporated into water-based and UV-curable coating systems where effective wetting and dispersion are important for uniform application.
In printing inks, Diethylhexyl Sodium Sulfosuccinate functions as a dispersing and wetting aid for pigments.
Diethylhexyl Sodium Sulfosuccinate can promote more uniform pigment distribution within the liquid medium and improve the penetration of ink into suitable substrates.
These properties are particularly relevant to formulations where pigment dispersion and controlled wetting influence print quality and processing behavior.
The plastics industry can use Diethylhexyl Sodium Sulfosuccinate as a dispersant for dyes and pigments during polymer processing.
Its surface-active structure helps improve the distribution of colorants within hydrophobic polymeric materials and resin systems.
Diethylhexyl Sodium Sulfosuccinate can also be used during the preparation of dispersions and resin systems where emulsification and stabilization of different phases are required.
In agricultural formulations, Diethylhexyl Sodium Sulfosuccinate is used as a wetting and penetrating agent in plant protection products.
Improved wetting allows spray droplets to spread more effectively over plant surfaces, while its surface-active properties can facilitate contact between the formulation and the treated plant material.
This makes it useful as a formulation adjuvant in pesticide and other crop-protection systems rather than as the active pesticidal substance itself.
Diethylhexyl Sodium Sulfosuccinate is also used in construction-related formulations as a wetting agent for cement particles.
Improved wetting can facilitate more uniform contact between cement grains and the surrounding liquid phase, supporting the performance of concrete and mortar formulations.
Diethylhexyl Sodium Sulfosuccinate is additionally used in release or anti-adhesive formulations designed to reduce the adhesion of freshly placed concrete to forming surfaces.
In mining and mineral-processing applications, Diethylhexyl Sodium Sulfosuccinate can be incorporated into dust-control formulations and processes involving mineral concentrates.
Diethylhexyl Sodium Sulfosuccinate has also been reported as an additive supporting the dewatering of flotation concentrates during filtration and drying.
These applications take advantage of its ability to modify surface wetting and interfacial behavior in systems containing hydrophobic mineral particles.
Diethylhexyl Sodium Sulfosuccinate can serve as an emulsifier in polymerization processes used to prepare polymer dispersions and resins.
Its surfactant activity can help stabilize dispersed phases during emulsion or suspension polymerization and support the formation of more uniform polymer systems.
Reported applications include dispersions and resins based on materials such as styrene-acrylic, acrylic, polyvinyl acetate, and styrene-butadiene systems.
Diethylhexyl Sodium Sulfosuccinate is used in pharmaceutical formulations as a surfactant and excipient because its wetting and solubilizing properties can improve the distribution of poorly water-compatible substances.
Diethylhexyl Sodium Sulfosuccinate is particularly well known as docusate sodium, which has been used as an oral stool-softening drug and in pharmaceutical preparations.
Its pharmaceutical applications are distinct from its cosmetic applications because dosage, purity, formulation, and regulatory requirements are specific to the intended medicinal use.
In food-related applications, Diethylhexyl Sodium Sulfosuccinate has been permitted for specific uses as an emulsifier, processing aid, and component of certain food-contact applications under applicable regulations.
Documented applications include its use in cocoa beverages at regulated concentrations and as a multipurpose food additive when the applicable specifications are met.
Diethylhexyl Sodium Sulfosuccinate has also been permitted for certain indirect food-contact applications involving adhesives, polymeric coatings, paper and paperboard, cellophane, and textile materials.
Diethylhexyl Sodium Sulfosuccinate is used in sugar-processing operations as a processing aid, where its surface-active properties can assist interactions between aqueous processing phases and other materials.
It has also been described as a stabilizer for hydrophilic colloids, helping maintain the distribution of colloidal components within suitable systems.
These applications take advantage of the same interfacial activity that makes the compound useful as a wetting and dispersing agent.
Diethylhexyl Sodium Sulfosuccinate is used in household and institutional cleaning formulations where rapid wetting and penetration of surfaces are important.
Its ability to reduce surface tension can help cleaning solutions spread over hydrophobic or contaminated surfaces and improve contact between the liquid phase and deposited materials.
Diethylhexyl Sodium Sulfosuccinate can also contribute to foaming and detergent performance when combined with compatible surfactants.
In paper and board processing, Diethylhexyl Sodium Sulfosuccinate can be used in applications requiring wetting, dispersing, or surface-active behavior.
Regulatory records also identify specific permitted food-contact uses involving paper and paperboard, including applications associated with defoaming agents used during manufacture.
The suitability of the ingredient depends on the particular grade, concentration, processing conditions, and applicable food-contact requirements.
The compound has also been investigated and used in mineral-processing applications, particularly where hydrophobic solids need to be wetted or where water removal from mineral concentrates is required.
It can assist dust-control formulations for mine and transport surfaces and has been used as an additive supporting the dewatering of flotation concentrates during filtration and drying.
These applications rely on its ability to modify solid–liquid interfaces and improve interactions between water and mineral particles.
Diethylhexyl Sodium Sulfosuccinate can be incorporated into corrosion-inhibitor formulations as a surface-active component.
Its amphiphilic structure can help distribute formulation components across metal–liquid interfaces and improve contact between the inhibitor system and the treated surface.
This use is generally associated with formulated corrosion-control systems rather than with the compound acting as the sole corrosion inhibitor.
In polymer and latex production, Diethylhexyl Sodium Sulfosuccinate can function as an emulsifier during emulsion or suspension polymerization.
Diethylhexyl Sodium Sulfosuccinate helps stabilize dispersed phases during polymer formation and can be used in systems involving acrylic, styrene-acrylic, polyvinyl acetate, and styrene-butadiene materials.
Its emulsifying behavior makes it useful when polymer particles need to remain distributed within an aqueous or other continuous phase during processing.
Diethylhexyl Sodium Sulfosuccinate can also be used in hydrophobic-resin formulations and pigment dispersions where uniform distribution of solid or liquid components is required.
Diethylhexyl Sodium Sulfosuccinate wetting and dispersing action can improve the incorporation of dyes, pigments, and other poorly water-compatible materials into formulation media.
This makes it relevant to resin systems, printing materials, plastics processing, and related industrial formulations.
In personal-care products, the ingredient can be incorporated into specialized formulations such as nail varnishes, hair sprays, eye-contour pencils, and other color-cosmetic products.
Diethylhexyl Sodium Sulfosuccinate principal contribution in these systems is associated with wetting, emulsification, dispersion, and improvement of formulation consistency rather than serving as the primary active cosmetic ingredient.
The CIR review documented its use in numerous cosmetic product categories, with reported use concentrations reaching 4.4% in eyebrow pencil formulations.
Safety Profile Of Diethylhexyl Sodium Sulfosuccinate:
Poison by intravenous route, moderately toxic by ingestion and intraperitoneal routes, A skin and severe eye irritant.
Docusate salts are used in oral formulations as therapeutic agents for their fecal softening and laxative properties.
As a laxative in adults, up to 500mg of docusate sodium is administered daily in divided doses; in children over 6 months old, up to 75 mg in divided doses is used.
The quantity of docusate sodium used as an excipient in oral formulations should therefore be controlled to avoid unintended laxative effects.
Adverse effects associated with docusate sodium include diarrhea, nausea, vomiting, abdominal cramps, and skin rashes.
Diethylhexyl Sodium Sulfosuccinate can cause skin irritation, particularly when concentrated material remains in contact with the skin for prolonged periods.
Experimental studies have shown irritation following exposure to concentrated solutions, while the Cosmetic Ingredient Review identified the substance as a cumulative irritant under exaggerated repeated-contact conditions.
For this reason, formulations containing the ingredient should be designed to minimize irritation, especially when they are intended for prolonged skin contact.
Eye exposure is an important safety concern because Diethylhexyl Sodium Sulfosuccinate can produce significant ocular irritation.
Experimental studies reported substantial eye irritation at higher concentrations, and some safety data sheets classify the substance as causing serious eye damage or serious eye irritation depending on the grade and classification system used.
Protective eyewear should therefore be used when handling concentrated raw material, and accidental eye contact should be followed by immediate and thorough rinsing.
The hazard classification of Diethylhexyl Sodium Sulfosuccinate is not completely identical across all regulatory and supplier sources.
For example, one GHS assessment classifies the substance as a skin irritant and eye irritant and also identifies reproductive toxicity and effects related to lactation, whereas another supplier SDS classifies it as Skin Irrit. 2 and Eye Dam. 1.
These differences demonstrate why the current safety data sheet for the exact commercial grade should be consulted before handling or formulating with the material.
Diethylhexyl Sodium Sulfosuccinate Procurement and Technical Support:
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Additional support can be provided regarding product specifications, available documentation, and the evaluation of suitable product options based on the intended application.
