PRODUCTS

DIISOPROPYL ETHER

DIISOPROPYL ETHER = DIPA

CAS NO:108-20-3
EC NO:203-560-6

Diisopropyl ether appears as a clear colorless liquid with an ethereal odor. Flash point -18°F. Less dense than water. Vapors heavier than air.

Industry Uses
Fuels and fuel additives
Functional fluids (closed systems)
Intermediates
Laboratory chemicals
Processing aids, not otherwise listed

Consumer Uses
Agricultural products (non-pesticidal)
Building/construction materials not covered elsewhere
Fuels and related products
Lubricants and greases
lab supply and pharmaceutical

Industry Processing Sectors
All other chemical product and preparation manufacturing
Petrochemical manufacturing
Petroleum lubricating oil and grease manufacturing
Pharmaceutical and medicine manufacturing
Plastic material and resin manufacturing
Plastics product manufacturing
Wholesale and retail trade

Diisopropyl ether is secondary ether that is used as a solvent.
Diisopropyl ether is a colorless liquid that is slightly soluble in water, but miscible with organic solvents.
Diisopropyl ether is used as an extractant and an oxygenate gasoline additive.
Diisopropyl ether is obtained industrially as a byproduct in the production of isopropanol by hydration of propylene.
Diisopropyl ether is sometimes represented by the abbreviation DIPE.

Properties
Chemical formula C6H14O
Molar mass 102.177 g·mol−1
Appearance Colorless liquid
Odor Sharp, sweet, ether-like
Density 0.725 g/ml
Melting point −60 °C (−76 °F; 213 K)
Boiling point 68.5 °C (155.3 °F; 341.6 K)
Solubility in water 2 g/L at 20 °C
Vapor pressure 119 mmHg (20°C)
Magnetic susceptibility (χ) -79.4·10−6 cm3/mol

Uses
Whereas at 20 °C, diethyl ether will dissolve 1% by weight water, diisopropyl ether only dissolves 0.88%.
Diisopropyl ether is used as a specialized solvent to remove or extract polar organic compounds from aqueous solutions, e.g. phenols, ethanol, acetic acid.
Diisopropyl ether has also been used as an antiknock agent.

Widely used as an extraction solvent in the pharmaceutical industry for manufacturing specific active ingredients, Diisopropyl ether also plays a role in the manufacturing process of numerous solvents used for resins and coatings, as well as in waste management.

Diisopropyl ether (also known as isopropyl ether, diisopropyl oxide, 2-isopropoxypropane, 2-2’oxybispropane, and DIPE) is a colourless liquid with a characteristic odour.
Diisopropyl ether has the chemical formula C6H14O and is only slightly soluble with water but is miscible with most organic solvents.

How is it produced?
To produce diisopropyl ether, propylene is first hydrated with water over a supported acidic catalyst to produce IPA (iso propanol). This is then reacted further with either propylene, or additional IPA, to form DIPE with reaction conditions controlled to promote the etherification with propylene.

What is Di Iso Propyl Ether used for?
Diisopropyl ether can be used in a wide variety of applications.
Diisopropyl ethers most common use is as a solvent as oil-based solutions dissolve in it. This makes it the ideal base for many paints, waxes, dyes and resins.
Diisopropyl ether is also used as a solvent in paint thinners and stain removers.

Diisopropyl ether can also be used as an extraction agent in metallurgy where, for example, it can recover gold from a nitric acid solution.
Diisopropyl ether also plays a role in the fuel industry as a gasoline blending component which, when added to gasoline, increases its octane levels.

Chemical manufacturers also find a use for Diisopropyl ether in organic synthesis and as a means of analysing chemicals, as the solvent nature of Diisopropyl ether makes it useful in chromatography.

Formula: C6H14O / (CH3)2CHOCH(CH3)2
Molecular mass: 102.18
Boiling point: 69°C
Melting point: -60°C
Relative density (water = 1): 0.7
Solubility in water: poor
Vapour pressure, kPa at 20°C: 15.9
Relative vapour density (air = 1): 3.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.5
Flash point: -28°C
Auto-ignition temperature: 443°C
Explosive limits, vol% in air: 1.4-7.9

Physical State :Liquid
Storage :Store at room temperature
Melting Point :-84.99° C
Boiling Point :65-70° C at 760 mmHg
Density :0.73 g/mL

Description
Diisopropyl ether is highly flammable, with a wide flammable range of 1.4%–21% in air. Boiling point is 156°F (68°C), flash point is ?18°F (?27°C), and ignition temperature is 830°F (443°C). Vapor density is 3.5, which is heavier than air. In addition to flammability, isopropyl ether is toxic by inhalation and a strong irritant, with a TLV of 250 ppm in air.

Chemical Properties
colourless liquid

Physical properties
Clear, colorless, volatile, flammable liquid with a penetrating, sweet, ether-like odor. Experimentally determined detection and recognition odor threshold concentrations were 70 μg/m3 (17 ppbv) and 220 μg/m3 (53 ppbv), respectively (Hellman and Small, 1974).

Uses
Diisopropyl ether is used as a solvent for oils,waxes, resins, and dyes; and as a varnishremover.

Uses
Solvent; chemical intermediate

Uses
As solvent; fuel additive.

General Description
A clear colorless liquid with an ethereal odor. Flash point -18°F. Less dense than water. Vapors heavier than air.

Air & Water Reactions
Highly flammable. Slightly soluble in water. Form explosive peroxide in storage. A flask of Isopropyl ether was heated on a steam bath with gentle shaking when an explosion occurred. In a second instance, an explosion occurred after practically all the ether had been distilled, [MCA Guide for Safety(1972)].

Reactivity Profile
Ethers, such as Isopropyl ether, can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert. Mixing Isopropyl ether in equal molar portions with any of the following substances in a closed container caused the temperature and pressure to increase: chlorosulfonic acid, nitric acid, [NFPA 1991].

Chemical Reactivity
Reactivity with Water: No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Unstable peroxides may form if the product contacts air for long time periods. These may explode spontaneously or when heated; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Industrial uses
Diisopropyl ether is a solvent of minor importance since its boiling point is intermediate between the two widely used solvents diethyl ether and acetone. Hazardous peroxides are formed more readily in isopropyl ether than in other dialkyl ethers.

Applications Of Diisopropyl Ether
API and intermediate synthesis
Paint thinners and stain removers
Extraction agent in metallurgy
Fuel additive
In Organic synthesis and HPLC

Advantages
Excellent Solvent power

Diisopropyl ether (DIPE) is an organic compound, secondary ether, used as a solvent in labs for certain reactions.

About this substance
Helpful information
Diisopropyl ether is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.

Diisopropyl ether is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses
Diisopropyl ether is used in the following products: fuels, adhesives and sealants, anti-freeze products, coating products, fillers, putties, plasters, modelling clay, finger paints, non-metal-surface treatment products, heat transfer fluids, hydraulic fluids, inks and toners, leather treatment products, lubricants and greases, polishes and waxes and textile treatment products and dyes.
Other release to the environment of Diisopropyl ether is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

Article service life
ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

Widespread uses by professional workers
Diisopropyl ether is used in the following products: pH regulators and water treatment products and laboratory chemicals.
Diisopropyl ether is used in the following areas: scientific research and development and health services.
Diisopropyl ether is used for the manufacture of: chemicals.
Other release to the environment of Diisopropyl ether is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and outdoor use as processing aid.

Formulation or re-packing
Diisopropyl ether is used in the following products: fuels, laboratory chemicals and extraction agents.
Release to the environment of Diisopropyl ether can occur from industrial use: formulation of mixtures and formulation in materials.

Uses at industrial sites
Diisopropyl ether is used in the following products: laboratory chemicals and fuels.
Diisopropyl ether is used in the following areas: scientific research and development.
Diisopropyl ether is used for the manufacture of: chemicals.
Release to the environment of Diisopropyl ether can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, in the production of articles, for thermoplastic manufacture, as processing aid and manufacturing of the substance.

Manufacture
Release to the environment of Diisopropyl ether can occur from industrial use: manufacturing of the substance, formulation of mixtures and in processing aids at industrial sites.

General Description
A clear colorless liquid with an ethereal odor. Flash point-18°F. Less dense than water. Vapors heavier than air.

Reactivity Profile
Ethers, such as DIISOPROPYL ETHER, can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert. Mixing diisopropyl ether in equal molar portions with any of the following substances in a closed container caused the temperature and pressure to increase: chlorosulfonic acid, nitric acid, [NFPA 1991].

Specifications

Appearance (Clarity) Clear
Appearance (Colour) Colourless
Appearance (Form) Liquid
Assay (GC) min. 98%
Density (g/ml) @ 20°C 0.722-0.724
Refractive Index (20°C) 1.368-1.369
Boiling Range 67-69°C
Peroxide (H2O2) max. 0.005%
Water (KF) max. 0.1%

Molecular Formula : C6H14O
Molecular Weight : 102.18
Part A
Storage : Room Temperature
Shelf Life : 60 Months
HSN Code : 29091990
IMDG Identification :UN No.:1159 , IMCO Class No.:3 , Packing Group:II

Diisopropyl ether can be used in a wide variety of applications.
Diisopropyl ethers most common use is as a solvent as oil-based solutions dissolve in it. This makes it the ideal base for many paints, waxes, dyes and resins.
Diisopropyl ether is also used as a solvent in paint thinners and stain remover.

General description
Diisopropyl ether (DIPE) is branched ether.
Diisopropyl ether is a peroxide forming solvent.
Diisopropyl ether is catalyzed by heat, light and oxygen. For such solvents small amount of stabilizers like BHT (butylated hydroxytoluene) or hydroquinone is added which removes the free radicals that form peroxides.
Diisopropyl ether has been proposed as a potential alternative oxygenated fuel additive. Several methods have been proposed for its synthesis using acetone as starting material. The molecular structure and conformation has been studied using gas-phase electron diffusion.
Diisopropyl ethers potential carcinogenicity has been studied in Sprague-Dawley rats.

Application
Diisopropyl ether may be used as a solvent in the following processes:
Resolution of secondary alcohols.
Enantioselective acylation of 1-phenethylamine.
Synthesis of aliphatic and aromatic cyanohydrins.

Product Description
Diisopropyl ether (also known as isopropyl ether, diisopropyl oxide, 2-isopropoxypropane, 2-2′oxybispropane, and DIPE) is a colourless liquid with a characteristic odour.
Diisopropyl etherhas the chemical formula C6H14O and is only slightly soluble with water but is miscible with most organic solvents.

USES:
1.Diisopropyl ethers most common use is as a solvent as oil-based solutions dissolve in it. This makes it the ideal base for many paints, waxes, dyes and resins.
Diisopropyl ether is also used as a solvent in paint thinners and stain removers.
2.Diisopropyl ether can also be used as an extraction agent in metallurgy where, for example, it can recover gold from a nitric acid solution
3.Chemical manufacturers also find a use for Diisopropyl ether in organic synthesis and as a means of analysing chemicals, as the solvent nature of Diisopropyl ether makes it useful in chromatography.

Description
Clear, colorless liquid, sharp, sweet, ether-like odor.

Uses
Solvent for animal, vegetable, mineral oils, waxes and resins, extraction of acetic acid from aq solutions, solvent for dyes in presence of small amt of alcohol, spotting compositions, paintermediate & varnish, rubber cements.

Diisopropyl ether has been used an extraction agent and as a solvent in paint thinners and stain removers.
Diisopropyl ether has also been considered for use as an additive to raise the octane rating of gasoline.
Diisopropyl ether is released into the environment through various waste streams associated with its laboratory use and the use and manufacture of removers.
Diisopropyl ether is considered mildly toxic. Short term exposures produce anesthetic effects similar to ethyl ether and irritate the eyes, the skin, and the respiratory tract.
Diisopropyl ether has been found many groundwater and surface water supplies. Many ethers are known to resist biodegradation and studies suggest that diisopropyl ether is resistant as well.

Keywords: solvent, gasoline additive, extraction agent

Applications :
As a solvent as a base for paints, waxes, dyes, resins
As a solvent in paint thinners and stain removers
As an extraction agent in metallurgy
In the fuel industry as an antiknock agent

Advantages :
Diisopropyl ether is a low odor fast evaporating solvent that is miscible with most common organic solvents
Dissolves only 0.5% by weight of water at 20oC as compared to diethyl ether (1%)

Diisopropyl ether, a clear, colorless liquid, is almost completely insoluble in water, but can be dissolved in ether or alcohol.

Main Application
Phenol reclamation solvent
Medical and antibiotic solvent
Chemical intermediate ingredient
Reagent

Fields of Use
solvent for extraction of fragrance, liquid source of smokeless powder and rubber cement, spalling agent and washing agent for lenses and metal parts

Diisopropyl ether is secondary ether that is used as a solvent.
Diisopropyl ether is a colorless liquid that is slightly soluble in water, but miscible with organic solvents.

IUPAC names
2,2'-Oxy-bis-propane
2,2'-oxydipropane
2-(propan-2-yloxy)propane
2-isopropoxypropane
2-Isopropoxypropane , Diisopropyl oxide , Isopropyl ether
2-propan-2-yloxypropane
di-isopropyl ether
Di-isopropyl ether
Diisopropyl ether
diisopropyl ether
Diisopropyl ether
Diisopropylether
Isopropyl ether
Isopropyl Ether (stabilized with HQ)
Propane, 2,2'-oxybis-

SYNONYMS:
108-20-3 [RN]
2-(propan-2-yloxy)propane
2,2'-Oxybispropane
203-560-6 [EINECS]
2-Isopropoxy propane
2-Isopropoxypropan [German] [ACD/IUPAC Name]
2-Isopropoxypropane [ACD/IUPAC Name]
2-Isopropoxypropane [French] [ACD/IUPAC Name]
Bis(isopropyl) ether
Diiospropyl ether
di-isopropyl ether
Diisopropyl ether [Wiki]
diisopropyl-ether
dipropan-2-yl ether
Ether isopropylique [French]
ether, isopropyl
Isopropyl ether
Izopropylowy eter [Polish]
MFCD00008880 [MDL number]
Propane, 2,2'-oxybis- [ACD/Index Name]
(iso-C3H7)2O