PRODUCTS

DIMETHYL ACETAMIDE

Dimethyl Acetamide is used as a reaction solvent for the manufacture of acryl and polyamide fibres.
Dimethyl Acetamide is also used for the manufacture of agro chemicals, dyes and pharmaceuticals.
Dimethyl Acetamide is commonly used as a solvent for fibers or in the adhesive industry.

CAS Number: 127-19-5
EC (EINECS) Number: 204-826-4
IUPAC Name: N,N-Dimethylacetamide
Molecular Formula: C4H9NO / CH3CON(CH3)2
Molecular Weight: ~87.12 g/mol

SYNONYMS:
Dimethylacetamide, N,N-Dimethylacetamide, DMAc, DMAC, Acetdimethylamide, N,N-Dimethylethanamide, Acetyl dimethylamine, Dimethylamide acetate, CH₃CON(CH₃)₂, N,N-Dimethylacetamide, Acetamide, N,N-dimethyl-, Acetdimethylamide, Dimethylacetamide, Dimethylamide acetate, DMA, CH3CON(CH3)2, Acetic acid dimethylamide, Acetyl dimethylamine, CBC 510337, DMAc, Hallucinogen, N,N-Dimethylethanamide, NSC 3138, SK 7176, U-5954, Dimethylamid kyseliny octove, N,N-DIMETHYLACETAMIDE, 127-19-5, Dimethylacetamide, Acetamide, N,N-dimethyl-, Acetdimethylamide, DMAc, Dimethyl acetamide, N,N-Dimethyl acetamide, Dimethylamide acetate, N,N-Dimethylethanamide, Dimethylacetone amide, Acetic acid, dimethylamide, Acetyldimethylamine, NSC 3138, Acetic acid dimethylamide, CBC 510337, SK 7176, Dimethylamid kyseliny octove, U-5954, DTXSID5020499, JCV5VDB3HY, NSC-3138, DTXCID90499, CHEBI:84254, NSC3138, RefChem:6046, 204-826-4, N.N-Dimethylacetamide, MFCD00008686, Hallucinogen, n-n-dimethylacetamide, N,N-Dimethylacetamide, anhydrous, N-N-Dimethylacetamide(DMAC), Acetamide, N,N-dimethyl-, labeled with deuterium (9CI), Dimethylacetamide, N,N-Dimethylacetamide, Acetyl dimethylamine, CAS-127-19-5, HSDB 74, N-Acetyldimethylamine, CCRIS 4623, N,N-dimethylacetoamide, N, N-dimethylacetamide, UNII-JCV5VDB3HY, Acetic acid-dimethylamide, Dimethylamid kyseliny octove [Czech], EINECS 204-826-4, dimethyacetamide, dimethylactamide, dimethylacteamide, AI3-15276, trimethylformamide, dimeihyl acetamide, dimethyl-acetamide, n-dimethylacetamide, N,N-dimethyacetamide, N,N-dimethylactamide, N,N dimethylacetamide, n,n,-dimethylacetamide, N,-N-dimethylacetamide, N,N -dimethylacetamide, N,N-di-methylacetamide, N,N-Dimethyl-acetamide, N,N-dimethylacet-amide, N, N-dimethylacetoamide, N,N-dimethyl acetoamide, n,n,-dimethyl-acetamide, N,N-dimethyl- acetamide, methane, dimethylcarbamoyl-, EC 204-826-4, SCHEMBL2415, SCHEMBL4882, CH3CON(CH3)2, N, N-Dimethylacetamide, EP, CHEMBL11873, SCHEMBL208814, N-N-Dimethylacetamide (DMAC), orb1909193, SCHEMBL1190178, SCHEMBL4820393, SCHEMBL6392062, N,N-Dimethylacetamide, >=99%, Acetic acid-dimethylamide 1000 microg/mL in Acetonitrile, DIMETHYLACETAMIDE [MART.], N,N-DIMETHYLACETAMIDE [II], N,N-DIMETHYLACETAMIDE [MI], WLN: 1VN1 & 1, BB_SC-12907, N,N-Dimethylacetamide, HPLC Grade, Tox21_202174, Tox21_302787, N,N-DIMETHYLACETAMIDE [HSDB], NSC820333, STL482892, N,N-DIMETHYLACETAMIDE [VANDF], ACETIC ACID,AMIDE,N,N-DIMETHYL, AKOS000118789, CS-W023195, HY-W042416, N,N-DIMETHYLACETAMIDE [USP-RS], NSC-820333, DIMETHYLACETAMIDE [EP MONOGRAPH], N,N-Dimethylacetamide, p.a., 99.5%, MSK000184-1000A, N,N-Dimethylacetamide, AR, >=99.5%, NCGC00159401-02, NCGC00159401-03, NCGC00256375-01, NCGC00259723-01, BP-31151, DA-65832, N,N-Dimethylacetamide, SAJ special grade, N,N-Dimethylacetamide, analytical standard, N,N-Dimethylacetamide, anhydrous, 99.8%, DB-041302, D0641, NS00006036, N,N-Dimethylacetamide, 99.5%, for analysis, N,N-Dimethylacetamide, for HPLC, >=99.7%, N,N-Dimethylacetamide, for HPLC, >=99.9%, N,N-Dimethylacetamide, ReagentPlus(R), 99%, C20339, N,N-Dimethylacetamide, ReagentPlus(R), >=99%, F044923, F996701, InChI=1/C4H9NO/c1-4(6)5(2)3/h1-3H, N,N-Dimethylacetamide, anhydrous, water < 50ppm, Q411452, Residual Solvent Class 2 - N,N-Dimethylacetamide, N,N-Dimethylacetamide, SAJ first grade, >=99.0%, N,N-Dimethylacetamide, UV HPLC spectroscopic, 99%, N,N-Dimethylacetamide, anhydrous, ZerO2(TM), 99.8%, N,N-Dimethylacetamide, Vetec(TM) reagent grade, 98%, F0001-0392, N,N-Dimethylacetamide, puriss. p.a., >=99.5% (GC), N,N-Dimethylacetamide, spectrophotometric grade, >=99%, N,N-Dimethylacetamide Solution in Acetonitrile, 1000ug/mL, N,N-Dimethylacetamide, for peptide synthesis, >=99.8% (GC), 5Y9, DMA, DMAC, Dimethyl acetamide, CH3CON(CH3)2, N,N-Dimethylacetamide, 99%, pure, dimethylacetamid, N,N-Dimethylethanamide, Acetic acid dimethylacetamide, DMAC, Dimethylacetamide, U-5954, acetamide, dimethyl-, acetamide, N,N-dimethyl-, acetamide, N,N-dimethyl- (8CI 9CI), acetdimethylamide, acetic acid dimethylamide, acetic acid N,N-dimethylamide, acetic acid, dimethylamide, acetyldimethylamine, N,N-dimethyl-acetamide, dimethylacetamide, N,N-dimethylacetamide, N,N'-dimethylacetamide, dimethylacetone amide, dimethylamide acetate, N,N-dimethylethanamide, DMAc, ethanoic acid N,N-dimethylamide, Acetamide, N,N-dimethyl-, Acetdimethylamide, Dimethylacetamide, Dimethylamide acetate, DMA, CH3CON(CH3)2, Acetic acid dimethylamide, Acetyl dimethylamine, CBC 510337, DMAc, Hallucinogen, N,N-Dimethylethanamide, NSC 3138, SK 7176, U-5954, Dimethylamid kyseliny octove, N,N-Dimethylacetamide, Acetic acid dimethylamide, Acetyldimethylamine, DMA Linear Formula: CH3CON(CH3)2 CAS Number: 127-19-5 Molecular Weight: 87.12 MDL number: MFCD00008686 EC Index Number: 204-826-4, Acetamide, N,N-dimethyl-, Acetdimethylamide, Acetic acid dimethylamide, Acetyl dimethylamine, CBC 510337, CH3CON(CH3)2, DMA, DMAc, Dimethylacetamide, Dimethylamid kyseliny octove, Dimethylamide acetate, Hallucinogen, N,N-Dimethylethanamide, N,N-dimethylacetamide [DMA], NSC 3138, SK 7176, U-5954, Acetamide, N,N-dimethyl-, Acetdimethylamide, Dimethylacetamide, Dimethylamide acetate, DMA, CH3CON(CH3)2, Acetic acid dimethylamide, Acetyl dimethylamine, CBC 510337, DMAc, Hallucinogen, N,N-Dimethylethanamide, NSC 3138, SK 7176, U-5954, Dimethylamid kyseliny octove, Acetic acid dimethylacetamide, N,N-Dimethylacetamide, 99%, pure, N,N-Dimethylacetamide, 99+%, for spectroscopy, N,N-Dimethylacetamide, 99+%, extra pure, N,N-DiMethylacetaMide, for spectroscopy, 99+% 250ML, N,N-DiMethylacetaMide, pure, 99% 1LT, N,N-DIMETHYLACETAMIDE, ANHYDROUS, 99.8%&, N,N-DIMETHYLACETAMIDE, FOR HPLC

Dimethyl Acetamide is a colorless liquid with ammonia-like odor
Dimethyl Acetamide is a colorless, high boiling, polar, hygroscopic liquid.
Dimethyl Acetamide is a good solvent for a wide range of organic and inorganic compounds and it is miscible with water, ethers, esters, ketones and aromatics compounds.

Dimethyl Acetamide is a colorless to yellow liquid with a faint, specific amine-like odor.
Dimethyl Acetamide is miscible with water and other organic substances.
Dimethyl Acetamide is a versatile intermediate with a variety of applications for example as solvent.

Dimethyl Acetamide is an excellent solvent with high solving power for high molecular-weight polymers and synthetic resins.
Dimethyl Acetamide is the organic compound with the formula CH3C(O)N(CH3)2.
This colorless, water miscible, high boiling liquid, Dimethyl Acetamide commonly used as a polar solvent in organic chemistry.

Dimethyl Acetamide is is miscible with most other solvents although it is poorly soluble in aliphatic hydrocarbons.
The chemical reactions of Dimethyl Acetamide are typical of N,N-disubstituted amides, therefore will hydrolize in the presence of acids:
CH3CON(CH3)2 + H2O + HCl → CH3COOH + (CH3)2NH2+Cl-

Dimethyl Acetamide is a useful as a medium for strong bases such as sodium hydroxide.
Dimethyl Acetamide is a synthetic organic compound that is produced from a reaction of dimethylamine and acetic acid or acetic anhydride.
Dimethyl Acetamide is a colorless to yellow liquid with a faint odor resembling ammonia.

Dimethyl Acetamide has similar density to water and is miscible with water and organic substances.
This organic compound, Dimethyl Acetamide, is commonly associated with many industrial uses, either as a starting material or an intermediate.
Dimethyl Acetamide is a good solvent that is used in polymer dissolution, especially in the fiber industry.

Dimethyl Acetamide is a member of the class of acetamides that is acetamide in which the hydrogens attached to the N atom have been replaced by two methyl groups respectively.
Metabolite observed in cancer metabolism.

Dimethyl Acetamide has a role as a human metabolite.
Dimethyl Acetamide is a member of acetamides and a monocarboxylic acid amide.
Dimethyl Acetamide is functionally related to an acetamide.

Dimethyl Acetamide appears as a clear colorless liquid with a faint odor similar to ammonia.
About Dimethyl Acetamide the same density as water.
Flash point of Dimethyl Acetamide is 145°F.

Dimethyl Acetamide's vapors heavier than air.
Dimethyl Acetamide is water soluble.
Dimethyl Acetamide is a dipolar, aprotic, high-boiling, oily solvent and reagent.

Dimethyl Acetamide is miscible with water and most oxygen- and nitrogen-containing organic solvents.
Dimethyl Acetamide has a faint ammonia odor.
Dimethyl Acetamide traces its roots at least as far back as 1914, when Marc Tiffeneau and K. Fuhrer at Hôpital Boucicaut (Paris) identified it as a product of heating N,N-dimethylbenzylamine and acetic anhydride to 200 °C in a sealed tube.

Then, in 1931, in a treatise on the synthesis of aliphatic amides, James A. Mitchell and E. Emmet Reid at Johns Hopkins University (Baltimore) described preparing Dimethyl Acetamide in 84% yield by heating acetic acid and dimethylamine at 150 °C for 3 h.
This, along with using acetic anhydride or methyl acetate instead of the acid, is the process for manufacturing Dimethyl Acetamide today.

Dimethyl Acetamide is also stable to strong bases; but it hydrolyzes in the presence of acids.
Dimethyl Acetamide is a organic compound that is miscible with most solvents.
Dimethyl Acetamide is a polar Lewis basic solvent used in organic synthesis, pharmaceutical and plasticizer production, gel permeation chromatography of cellulose, etc.

Dimethyl Acetamide is a colorless, high boiling, polar, hygroscopic liquid.
Dimethyl Acetamide is a good solvent for a wide range of organic and inorganic compounds and it is miscible with water, ethers, esters, ketones and aromatics compounds.

USES and APPLICATIONS of DIMETHYL ACETAMIDE:
Dimethyl Acetamide is used in the production of polyacrylonitrile and polyurethane based fibers, films and coatings.
Dimethyl Acetamide is a versatile solvent due to its high boiling point and good thermal and chemical stability.
Applications of Dimethyl Acetamide: Solvent, Chemical Intermediate

Recommended Use of Dimethyl Acetamide: Acrylic and elastane fibers, Pharmaceuticals, Coatings, Polyimide resins, and Cellulose fibers.
Dimethyl Acetamide is used as a reaction solvent for the manufacture of acryl and polyamide fibres.
Dimethyl Acetamide is also used for the manufacture of agro chemicals, dyes and pharmaceuticals.

Dimethyl Acetamide is commonly used as a solvent for fibers or in the adhesive industry.
Dimethyl Acetamide is also employed in the production of pharmaceuticals and plasticizers as a reaction medium.
Dimethyl Acetamide is used as a polar solvent in organic synthesis as well as in reactions involving strong bases such as sodium hydroxide.

Dimethyl Acetamide is also used as a solvent for fibers like polyacrylonitrile, spandex, as an excipient in drugs viz. vumon, busulfex and in the adhesive industry.
Dimethyl Acetamide finds application as a reaction medium in the production of pharmaceuticals, agrochemicals, dyes and plasticizers.

Dimethyl Acetamide is widely used in polymer industry due to its high solving power for high molecular-weight polymers and synthetic resins.
Dimethyl Acetamide plays an important role as a catalyst in various reactions viz. cyclization, halogenation, cynidation, alkylation and dehydrogenation and increases the yield of main products.

Dimethyl Acetamide is also used as an extracting agent for oil and gases, in paint removers, in the production of photo-resist stripping compounds and as booster solvent in coatings.
Dimethyl Acetamide is an excellent solvent and often acts as a catalyst in halogenation, cyclization, and alkylation reactions.

Dimethyl Acetamide is an important industrial solvent for polyacrylonitrile, vinyl resins, cellulose derivatives, styrene polymers and linear polyesters.
Dimethyl Acetamide is also used in all analytical laboratories as a major component of mobile phase in High Performance Liquid Chromatography (HPLC) and in Liquid Chromatography - Mass Spectrometry (LC-MS).

Dimethyl Acetamide lithium chelate complexes intercalate cationic sites in layered silicates.
Dimethyl Acetamide is primarily used as an industrial solvent and intermediate in the manufacture of pharmaceuticals, fine chemicals, agrochemicals, polymers, and resins.

Dimethyl Acetamide is also used as a spinning solvent in the production of fibers of various polymers, including acrylic, polyurethane, polyurea copolymer, and meta-aramid.
Moreover, this aprotic dipolar solvent, Dimethyl Acetamide, is also used in X-ray and photographic products and in the production of polyimide films.

Dimethyl Acetamide films are produced for a variety of industries, including consumer electronics, solar photovoltaic and wind energy, aerospace, automotive, and industrial applications.
Dimethyl Acetamide has other minor uses, including removal of ink, stripping of paint, and also for laboratory use.

Main Applications of Dimethyl Acetamide: High grade solvent, pharmaceuticals, agricultural chemicals
Dimethyl Acetamide is used as a solvent for producing fibers and for synthesizing organic compounds, notably pharmaceuticals.
Dimethyl Acetamide's broad range of miscibility makes it useful in mixed solvents.

Applications of Dimethyl Acetamide: Fibers, HTF - pharmaceutical processing, Process solvents.
Dimethyl Acetamide is used in the production of polyacrylonitrile and polyurethane based fibers, films and coatings.
The polar nature of Dimethyl Acetamide enables it to act as a combined solvent and reaction catalyst in many reactions producing high yields and pure product in short time periods.

Dimethyl Acetamide is a dipolar aprotic solvent used for many organic reactions and industrial applications.
Dimethyl Acetamide is a versatile solvent due to its high boiling point and good thermal and chemical stability.

Acrylic fibres: Dimethyl Acetamide is applied as solvent in wet spinning processes for the production of acrylic fibres.
Elasthane fibres: In the production of polyurethane-based elasthane fibres, Dimethyl Acetamide is the solvent of choice given its evaporation speed, whether it is used in wet or dry spinning processes.

-Pharmaceuticals use of Dimethyl Acetamide:
Dimethyl Acetamide can be used both as a solvent and as a reagent in the production of various pharmaceuticals.
In the production of novel x-ray contrast media, Dimethyl Acetamide is used as a solvent.

Cephalosporins, which are among one of the leading classes of antibiotics, are partly produced from derivatives of 7-ADCA (7-aminodeacetoxy-cephalosporanic acid).
Dimethyl Acetamide is used in the manufacturing process.

-Various polymers use of Dimethyl Acetamide:
Dimethyl Acetamide is a good solvent for polyimide resins, both in coating and film production.
Dimethyl Acetamide is also the ideal solvent for the production of dialyser membranes, based on polysulfones.
A mixture of Dimethyl Acetamide and lithium chloride is a useful solvent for cellulose fibres in several applications.

CHEMICAL PROPERTIES of DIMETHYL ACETAMIDE:
Dimethyl Acetamide is a transparent colorless liquid.
The organic solvent, Dimethyl Acetamide, can be mixed with any water, alcohol, ether, ester, benzene, chloroform, and aromatic compounds.

Dimethyl Acetamide has a very good solvency for many resins and polymers.
Dimethyl Acetamide is used in the production of acrylic fibers, films, sheets, and coatings, and as a reaction medium and intermediate in organic syntheses.

Dimethyl Acetamide occurs as a clear, colorless, slightly hygroscopic liquid with a weak ammonia-like or fish-like odor.
odor threshold concentration is 46.8 ppmv.
Dimethyl Acetamide is soluble in a wide variety of solvents.

PREPARATION of DIMETHYL ACETAMIDE:
Dimethyl Acetamide is prepared by reaction of dimethylamine with acetic acid, acetic anhydride, or acetate esters.
Heating dimethylamine acetate with, or without a catalyst affords Dimethyl Acetamide.
Reaction of dimethylamine with acetate esters requires a catalyst; sodium methoxide is typically used.

BENEFITS of DIMETHYL ACETAMIDE:
*High boiling point
*Good thermal and chemical stability
*Hygroscopic

PRODUCTION METHOD of DIMETHYL ACETAMIDE:
Dimethyl Acetamide has been produced by the reaction of acetic acid with dimethylamine.

REACTIVITY PROFILE of DIMETHYL ACETAMIDE:
Dimethyl Acetamide is an amide.
Dimethyl Acetamide is incompatible with oxidizing agents and halogenated compounds.
Exothermic reactions occur with carbon tetrachloride and hexachlorocyclohexane.
Dimethyl Acetamide can react violently in the presence of iron.

HOW IS DIMETHYL ACETAMIDE USED?
Dimethyl Acetamide is used primarily in industrial settings.
Dimethyl Acetamide occurs in products only as an unintended manufacturing residue (leftover from the manufacturing process).
Dimethyl Acetamide is commonly used for polymer dissolution in the man-made fibre production industry, as a solvent in the production of photoresist strippers used in the manufacture of electronic components, as a production solvent in the pharmaceutical, photography and cosmetic industries, as a feedstock in the coating industry and in sealant applications in aircraft.
Dimethyl Acetamide is not manufactured in Canada, but is imported into Canada.

PHYSICAL and CHEMICAL PROPERTIES of DIMETHYL ACETAMIDE:
Chemical Name (Preferred): N,N-Dimethylacetamide
Common Name: Dimethylacetamide (DMAc, DMAC)
CAS Number: 127-19-5
EC (EINECS) Number: 204-826-4
IUPAC Name: N,N-Dimethylacetamide
Chemical Formula: C₄H₉NO
Molecular Weight: ~87.12 g/mol

State at Room Temperature: Clear, colorless to slightly yellow liquid
Odor: Faint ammonia-like or fish-like odor
Density: ~0.94 g/cm³ at 20–25 °C
Melting Point: Approximately −18.6 °C
Boiling Point: ~165 °C
Vapor Pressure: ~1.8–2.7 mmHg at 25 °C
Vapor Density: ~3.01 (air = 1)
Solubility: Miscible with water and most organic solvents

Flash Point: ~70 °C closed cup
Flash point: 63 °C (145 °F; 336 K)
Autoignition temperature: 490 °C (914 °F; 763 K)
Explosive limits: 1.8–11.5%
Chemical formula: C4H9NO
Molar mass: 87.122 g·mol−1
Appearance: Colorless liquid
Odor: Ammoniacal

Density: 0.937 g/mL
Melting point: −20 °C (−4 °F; 253 K)
Boiling point: 165.1 °C; 329.1 °F; 438.2 K
Solubility in water: Miscible
log P: −0.253
Vapor pressure: 300 Pa
UV-vis (λmax): 270 nm
Refractive index (nD): 1.4375
Viscosity: 0.945 mPa·s [2]

Thermochemistry
Heat capacity (C): 178.2 J/(K·mol)
Std enthalpy of formation (ΔfH⦵298): −300.1 kJ/mol
Std enthalpy of combustion (ΔcH⦵298): −2.5835–−2.5805 MJ/mol
Molecular Weight: 87.12 g/mol
Compound Canonicalized: Yes
XLogP3: -0.8
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1

Rotatable Bond Count: 0
Exact Mass: 87.068413911 Da
Monoisotopic Mass: 87.068413911 Da
Topological Polar Surface Area: 20.3 Å²
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 58.6
Isotope Atom Count: 0

Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
CBNumber: CB8853004
Molecular Formula: C4H9NO

Molecular Weight: 87.12
MDL Number: MFCD00008686
MOL File: 127-19-5.mol
Melting point: -20 °C (lit.)
Boiling point: 164.5-166 °C (lit.)
Density: 0.937 g/mL at 25 °C (lit.)
Vapor density: 3.89 (vs air)
Vapor pressure: 40 mm Hg (19.4 °C)
Refractive index: n20/D 1.439(lit.)

Flash point: 158 °F
Storage temp.: Store below +30°C.
Solubility: >1000g/l soluble
Form: Liquid
pKa: -0.41±0.70(Predicted)
Color: Colorless to yellowish
pH: 4 (200g/l, H2O, 20℃)
Odor: Faint ammonia odor
pH Range: 4 at 200 g/l at 20 °C

Relative polarity: 6.3
Appearance: Solid Powder
Evaporation Rate: <0.17
Odor Threshold: 0.76ppm
Explosive limit: 1.7-11.5%(V)
Water Solubility: miscible
λmax: λ: 270 nm Amax: 1.00
λ: 280 nm Amax: 0.30
λ: 290 nm Amax: 0.15
λ: 310 nm Amax: 0.05
λ: 320 nm Amax: 0.03
λ: 360-400 nm Amax: 0.01

Merck: 14,3227
BRN: 1737614
Exposure limits: NIOSH REL: TWA 10 ppm (35 mg/m3), IDLH 300 ppm; OSHA PEL: TWA 10 ppm; ACGIH TLV: TWA 10 ppm (adopted).
Dielectric constant: 37.8（25℃）
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey: FXHOOIRPVKKKFG-UHFFFAOYSA-N
LogP: -0.77 at 25℃
Surface tension: 37.13mN/m at 293.15K

CAS DataBase Reference: 127-19-5(CAS DataBase Reference)
EWG's Food Scores: 3
FDA UNII: JCV5VDB3HY
Proposition 65 List: N,N-Dimethylacetamide
IARC: 2B (Vol. 123) 2020
NIST Chemistry Reference: Acetamide, N,N-dimethyl-(127-19-5)
EPA Substance Registry System: Dimethylacetamide (127-19-5)
UNSPSC Code: 41116107
NACRES: NA.24

Linear Formula: CH3CON(CH3)2
CAS Number: 127-19-5
Molecular Weight: 87.12
NACRES: NA.21
PubChem Substance ID: 329751718
eCl@ss: 39031204
UNSPSC Code: 12352111
EC Number: 204-826-4
MDL number: MFCD00008686
Beilstein/REAXYS Number: 1737614

Molecular Formula / Molecular Weight: C4H9NO = 87.12
Physical State (20 deg.C): Liquid
Storage Temperature: Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN: 127-19-5
Reaxys Registry Number: 1737614
PubChem Substance ID: 87567287
SDBS (AIST Spectral DB): 448
Merck Index (14): 3227

MDL Number: MFCD00008686
Compound Canonicalized: Yes
Appearance: colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.93700 @ 25.00 °C.
Melting Point: -18.59 °C. @ 760.00 mm Hg (est)
Boiling Point: 165.00 °C. @ 760.00 mm Hg

Vapor Pressure: 1.800000 mmHg @ 25.00 °C. (est)
Vapor Density: 3.01 (Air = 1)
Flash Point: 158.00 °F. TCC (70.00 °C.)
logP (o/w): -0.770
Soluble in: water, 1.00E+06 mg/L @ 25 °C (exp)
Soluble in: water, 5.747e+005 mg/L @ 25 °C (est)
Physical state: liquid

Color: colourless
Odor: Ammonia odor
Odor Threshold: 44,4 ppm
Melting point/ range: -20 °C
Method: lit.
Boiling point/boiling range: 164,5 - 166 °C
Method: lit.
Flammability: No data available

Upper explosion limit / Upper flammability limit: Upper explosion limit 11,5 %(V) (160 °C)
Lower explosion limit / Lower flammability limit: Lower explosion limit 1,8 %(V) (100 °C)
Flash point: 64 °C(1.013 hPa)
Method: closed cup
Autoignition temperature: 345 °C (999 - 1.011 hPa)
Auto-flammability Decomposition temperature: No data available
pH: ca. 4 (20 °C)
Concentration: 200 g/l

Viscosity, dynamic: 0,92 mPa.s (25 °C)
Viscosity, kinematic: No data available
Flow time: No data available
Water solubility: 1.000 g/l (20 °C) completely miscible
Partition coefficient: n-octanol/water: log Pow: -0,77
Method: (experimental)
Bioaccumulation is not expected. (Lit.)
Vapor pressure: 2 hPa (21,7 °C)

Relative density: No data available
Density: 0,937 g/mL (25 °C) Method: lit.
Relative vapour density: 3,01 (Air = 1.0)
Explosives: Not classified as explosive.
Oxidizing properties: none
Burning rate: No data available
Self-ignition: 345 °C 999 - 1.011 hPa Method: DIN 51794
Evaporation rate: No data available

Molecular weight: 87,12 g/mol
CAS: 127-19-5
Compound Canonicalized: Yes
IUPAC Name: N,N-dimethylacetamide
Molecular Formula: C4H9NO
InChI Key: FXHOOIRPVKKKFG-UHFFFAOYSA-N
SMILES: CN(C)C(C)=O
Molecular Weight (g/mol): 87.12
Synonym: dimethylacetamide|N,N'-dimethylacetamide|hallucinogen|N,N-dimethyl acetamide

MDL Number: MFCD00008686
Appearance (Color): Clear colorless
GC: >=99.4 %
Residue after evaporation: =<0.005 %
Appearance (Form): Liquid
Infrared spectrum: Conforms
Water: =<0.005 %
Chemical Formula: CH3CON(CH3)2

Molecular Weight: 87.12
Appearance: Colorless liquid
Odor: Smell of Ammonia
Specific Gravity (liquid 25℃/4℃): 0.9366
Boiling Point (℃ 760mmHg): 165.5
Freezing Point (℃ 760mmHg): -20
Flash Point (℃ Tagliabue (Tag) Closed Cup): 63
Ignition Temperature (℃): 490
Flammability Limits (vol%): 2.0-11.5

Vapour Pressure (mmHg 25℃): 1.3
Viscosity (CP 25℃): 0.92
Solubility: Readily soluble in water and ethanol
Stability& Reativity: Stable under temperature.
CAS number: 127-19-5
EC index number: 616-011-00-4
EC number: 204-826-4
Hill Formula: C₄H₉NO
Chemical formula: CH₃CON(CH₃)₂
Molar Mass: 87.12 g/mol

HS Code: 2924 19 00
Boiling point: 165 - 166 °C (1013 hPa)
Density: 0.94 g/cm3 (20 °C)
Explosion limit: 1.7 - 11.5 %(V)
Flash point: 64 °C
Ignition temperature: 400 °C
Melting Point: -20 °C
pH value: 4 (200 g/l, H₂O, 20 °C)
Vapor pressure: 1.76 hPa (20 °C)
Solubility: >1000 g/l soluble

Compound Canonicalized: Yes
Density: 0.942 g/mL
Molar volume: 92.5 mL/mol
Refractive index: 1.438
Molecular refractive power: 24.31 mL/mol
Dielectric constant: 37.78
Dipole moment: 3.72 D
Melting point: -20 °C
Boiling point: 166 °C
Vapour pressure: 1 Torr

Surface tension: 32.43 dyn/cm
Viscosity: 2.14 cP
Critical temperature: 385 °C
Critical pressure: 40.3 atm
Evaporation rate (ether): 172.0
Evaporation rate (butyl acetate): 0.1
Solubility in water: 100 % w/w
Solubility of water: 100 % w/w
Log10 partition octanol / water: -0.70

Snyder P': 6.5
Snyder X: Xe: 0.4 Xd: 0.2 Xn: 0.4
Dimroth ET: 43.7
Hildebrant solubility parameter (δ): 11.0
Hansen solubility parameter: δd: 8.2 (cal/mL)½ δp: 5.6 (cal/mL)½ δh: 5.0 (cal/mL)½
Specific heat capacity: 42.0 cal/molK
Linear Formula: CH3CON(CH3)2
CAS Number: 127-19-5

Molecular Weight: 87.12
UNSPSC Code: 12352111
NACRES: NA.21
PubChem Substance ID: 57648218
EC Number: 204-826-4
Beilstein/REAXYS Number: 1737614
MDL number: MFCD00008686
Grade: anhydrous
Assay: 99.8%

Bp: 164.5-166 °C (lit.)
Vapor pressure: 2 mmHg (25 °C)
4 mmHg (38 °C)
Product: N,N-Dimethylacetamide
CAS: 127-19-5
Formula: C4H9NO
Synonym: DMAc, Acetamide, N,N-dimethyl-
Density: 0.942
Surface Tension: 32.43 dynescm
Dielectric Constant: 37.78

Auto/Self Ignition Temperature: temp. 490 c
Assay: >= 99.8%
Alkalinity: <= 0.0010% (as DMA)
Water: <= 0.015%
Color, APHA: <= 5
Appearance: Clear liquid
Acidity (as Acetic Acid): <= 0.010%
Vapor Pressure: 1.3 mm hg
Melting Point: -20 c

Odor: weak ammonia fishy odor
Refractive Index: 1.437
Molecular weight: 87.12
Color: colorless clear oily liquid
Flash Point: 70 c
Boiling Point: 165-167 c
Physical state: liquid
Color: colourless
Odor: Ammonia odor

Melting point/freezing point: Melting point/ range: -20 °C
Initial boiling point and boiling range: 164,5 - 166 °C
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: Upper explosion limit: 11,5 %(V)
Lower explosion limit: 1,8 %(V)
Flash point: 64 °C - closed cup
Autoignition temperature: 345 °C at 999 - 1.011 hPa - DIN 51794
Decomposition temperature: No data available
pH: ca.4 at 200 g/l at 20 °C

Viscosity:
Viscosity, kinematic: No data available
Viscosity, dynamic: 0,92 mPa.s at 25 °C
Water solubility: 1.000 g/l at 20 °C - completely miscible
Partition coefficient: n-octanol/water: log Pow: -0,77 -
Bioaccumulation is not expected., (Lit.)
Vapor pressure: 2 hPa at 21,7 °C
Density: 0,937 g/mL at 25 °C
Relative density: No data available

Relative vapour density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none
Other safety information: Dissociation constant -0,19 at 25 °C
Relative vapour density: 3,01 - (Air = 1.0)
Melting point: -20 °C (lit.)
Boiling point: 164.5-166 °C (lit.)
density: 0.937 g/mL at 25 °C (lit.)

vapor density: 3.89 (vs air)
vapor pressure: 40 mm Hg ( 19.4 °C)
refractive index: n20/D 1.439(lit.)
Fp: 158 °F
storage temp.: Store below +30°C.
solubility: >1000g/l soluble
form: Liquid
pka: -0.41±0.70(Predicted)
color: Colorless to yellowish

PH: 4 (200g/l, H2O, 20℃)
Odor: Faint ammonia odor
PH Range: 4 at 200 g/l at 20 °C
Relative polarity: 6.3
Appearance: Solid Powder
Odor Threshold: 0.76ppm
explosive limit: 1.7-11.5%(V)
Water Solubility: miscible

λmax: λ: 270 nm Amax: 1.00
λ: 280 nm Amax: 0.30
λ: 290 nm Amax: 0.15
λ: 310 nm Amax: 0.05
λ: 320 nm Amax: 0.03
λ: 360-400 nm Amax: 0.01
Merck: 14,3227
BRN: 1737614
Exposure limits: NIOSH REL: TWA 10 ppm (35 mg/m3), IDLH 300 ppm;
OSHA PEL: TWA 10 ppm; ACGIH TLV: TWA 10 ppm (adopted).

Dielectric constant: 37.8（25℃）
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey: FXHOOIRPVKKKFG-UHFFFAOYSA-N
LogP: -0.77 at 25℃
Surface tension: 37.13mN/m at 293.15K
CAS DataBase Reference: 127-19-5(CAS DataBase Reference)
NIST Chemistry Reference: Acetamide, N,N-dimethyl-(127-19-5)

IARC: 2B (Vol. 123) 2020
EPA Substance Registry System: Dimethylacetamide (127-19-5)
Molecular weight: 87.12
Boiling point: 166.1°C
Vapor pressure: 1.3 Torr at 25°C
Freezing point: -20°C
Refractive index: 1.4384 at 20°C
Density: 0.9415 g/mL (7.857 lb/gal) at 20°C

Density: 0.9366 g/mL (7.816 lb/gal) at 25°C
Dielectric constant: 37.78 at 25°C
Dipole moment: 3.72 D at 25°C
Solvent group: 3
Polarity index (P'): 6.5
Viscosity: 2.14 cP at 20°C
Surface tension: 32.43 dyn/cm at 30°C
Solubility in water: Miscible in all proportions

FIRST AID MEASURES of DIMETHYL ACETAMIDE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of DIMETHYL ACETAMIDE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of DIMETHYL ACETAMIDE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of DIMETHYL ACETAMIDE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of DIMETHYL ACETAMIDE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of DIMETHYL ACETAMIDE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available