DIMETHYL-P-TOLUIDINE

Dimethyl-p-toluidine a clear colorless liquid with an aromatic odor. 
Dimethyl-p-toluidine, also known as N,N-Dimethyl-p-toluidine, is an organic compound with the chemical formula C9H13N. 
Dimethyl-p-toluidine is a substituted aromatic amine, specifically a derivative of toluene. 

CAS Number: 99-97-8
Molecular Formula: C9H13N
Molecular Weight: 135.21
EINECS Number: 202-805-4

N,N-Dimethyl-p-toluidine, 99-97-8, N,N,4-TRIMETHYLANILINE, Dimethyl-p-toluidine, Benzenamine, N,N,4-trimethyl-, Dimethyl-4-toluidine, N,N-Dimethyl-4-methylaniline, N,N,4-Trimethylbenzenamine, p-Methyl-N,N-dimethylaniline, p-(Dimethylamino)toluene, N,N-Dimethyl-p-tolylamine, 4-Dimethylaminotoluene, N,N-Dimethyl-para-toluidine, p-Toluidine, N,N-dimethyl-, NSC 1785, p,N,N-Trimethylaniline, Dimetil-p-toluidina, N,N-Dimethyl-4-toluidine, 1-(Dimethylamino)-4-methylbenzene, 4,N,N-Trimethylaniline, S8XC5939VU, DTXSID0021832, NSC-1785, NL 65-100, DTXCID401832, p-N,N-Trimethylaniline, CAS-99-97-8, Dimetil-p-toluidina [Italian], CCRIS 1001, EINECS 202-805-4, UNII-S8XC5939VU, Benzeneamine,N,N,4-trimethyl-, dimethyltolylamine, HSDB 8202, MFCD00008316, N,4-Trimethylaniline, dimethyl-(p-tolyl)-amine, EC 202-805-4, Benzenamine,N,4-trimethyl-, SCHEMBL28378, MLS001050174, 4-dimethylamino-1-methylbenzene, 4,N,N-Trimethylaniline, 99%, CHEMBL1462714, DIMETHYLTOLYLAMINE [INCI], N,N-Dimethyl-p-methylphenylamine, NSC1785, Tox21_201370, Tox21_300062, AC-368, AKOS015915159, N,N-DIMETHYL-P-TOLUIDINE [IARC], NCGC00091397-01, NCGC00091397-02, NCGC00091397-03, NCGC00254201-01, NCGC00258922-01, SMR001216586, D0807, FT-0629511, FT-0636092, FT-0656134, E75885, EN300-7266829, 4,N,N-Trimethylaniline, purum, >=98.0% (GC), Q2051705, W-100002, Z1002998236, N,N-DIBENZYL-1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE.

Dimethyl-p-toluidine is used to make acrylic resins and denture materials. 
Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
The structure of Dimethyl-p-toluidine consists of a toluene (methylbenzene) ring with two methyl (CH3) groups attached to the amino (NH2) group.

Dimethyl-p-toluidine is used as a polymerization catalyst for Intermediate for primarily polyesters and acrylate and epoxy resins. 
Dimethyl-p-toluidine can be used as a hardner for dental cements and for adhesives. 
Dimethyl-p-toluidine is used as an intermediate for photographic chemicals, colorants and pharmaceuticals.

Dimethyl-p-toluidine otherwise known as p,N,N-Trimethylaniline is an aromatic compound that is a member of the aniline family. 
Dimethyl-p-toluidine is supplied by Actylis in the form of a clear yellow liquid that is immiscible in water that has an aromatic odour. 
Dimethyl-p-toluidine is often used as a catalyst for the polymerization of polyesters and epoxy resins. 

Dimethyl-p-toluidine has also been used as a chemical hardener in dentistry adhesives. 
Dimethyl-p-toluidine has also been used as a chemical intermediate in the synthesis of various pharmaceutical products, colorants and artificial fingernail preparations as well as a raw material in the synthesis of industrial adhesives.
Dimethyl-p-toluidine was listed as a high production volume chemical in the USA, indicating that >  1 million pounds [approximately 454 tonnes] were produced or imported between 1990 and 1994 annually (HSDB, 2015).

Annual United States production volumes of Dimethyl-p-toluidine from 1986 to 2014 are given in Table 1.1. With annual production reported to be 1–10 million pounds [approximately 454–4536 tonnes] in 2014, it remains a high production volume chemical in the USA (HSDB, 2015). 
The total tonnage band per annum is estimated to be between 10 and 100 tonnes in the European Union (ECHA, 2015). 
Globally, more than 130 suppliers of Dimethyl-p-toluidine could be identified in 2016 with about two thirds (> 80) located in Asia (ChemicalBook Inc., 2016).

Dimethyl-p-toluidine is used as a chemical bond for polyesters, acrylate, and epoxy resins. 
Dimethyl-p-toluidine is also used as a hardener for dental cements and in adhesives. 
Dimethyl-p-toluidine can be found in dental products, photographic materials, colorants, and pharmaceuticals.

Dimethyl-p-toluidine cannot initiate acrylonitrile (AN) polymerization in the dark, but the polymerization is extremely fast under the light. 
Dimethyl-p-toluidine initiated acrylonitrile (AN) photopolymerization is carried out according to a free radical mechanism. 
When a trace amount of free radical capture agent is added, the polymerization is completely stopped.

For example, Dimethyl-p-toluidine, when human 200ppm 2,2,6,6, 6-tetramethylpiperidol nitroxide radical is added, acrylonitrile (AN) does not have any polymerization after 1.5 hours of light, and under the same conditions, no free radical capture agent is added, and polyacrylonitrile white precipitate appears in two minutes.
Dimethyl-p-toluidine is used as a polymerization catalyst for polyesters, acrylate and epoxy resins. 
Dimethyl-p-toluidine is also used as a hardener for dental cements and in adhesives. 

Dimethyl-p-toluidine serves as an intermediate for photographic chemicals, in industrial glues, in artificial fingernail preparations, colorants, pharmaceuticals.
Dimethyl-p-toluidine is a high-purity chemical that is used as a catalyst in the production of various polymers and resins. 
Dimethyl-p-toluidine is also used as an initiator for polymerization reactions and as an accelerator for curing processes in epoxy resins. 

Dimethyl-p-toluidine is highly flammable and toxic if ingested, inhaled or absorbed through the skin, so proper safety precautions must be taken when handling it. 
Dimethyl-p-toluidine should be stored in a tightly sealed container away from sources of heat or ignition. 
Performance data shows that Dimethyl-p-toluidine meets 99% purity standards and has no significant environmental impact when handled properly.

Dimethyl-p-toluidine is used as a polymerization catalyst and intermediate in preparing polyesters and acrylate and epoxy resins. 
Dimethyl-p-toluidine can be used as a hardner for dental cements and for adhesives. It is used as an intermediate for photographic chemicals, colorants and pharmaceuticals.
Dimethyl-p-toluidine is used to make acrylic resins and denture materials. 

Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
Dimethyl-p-toluidine should be handled with care as it is a chemical reagent.
Dimethyl-p-toluidine is important to follow safety guidelines and use appropriate protective measures when working with this compound.

Dimethyl-p-toluidine is typically a colorless to pale yellow liquid.
Dimethyl-p-toluidine has a characteristic amine-like odor.
Dimethyl-p-toluidine has a melting point of around -49 to -46 degrees Celsius.

The boiling point is approximately 199 degrees Celsius.
Dimethyl-p-toluidine contains an amino (-NH2) group, and it is an aromatic amine.
Dimethyl-p-toluidine is soluble in organic solvents but has limited solubility in water.

Dimethyl-p-toluidine is a reactive compound and should be handled with caution.
Dimethyl-p-toluidine may react vigorously with oxidizing agents.
Due to its reactivity, Dimethyl-p-toluidine is important to store and handle it away from incompatible materials.

Dimethyl-p-toluidine is often used as a catalyst in chemical reactions, particularly in the curing and polymerization processes of certain resins.
In polyurethane foam production, Dimethyl-p-toluidine acts as a tertiary amine catalyst promoting the reaction between isocyanates and polyols.
Dimethyl-p-toluidine is involved in the curing reactions of epoxy resins, where it helps initiate the polymerization process.

Dimethyl-p-toluidine is also used in the production of certain polyurethane materials, including foams, coatings, and adhesives.
Dimethyl-p-toluidine is utilized in various industrial applications, including the manufacturing of plastics, adhesives, and coatings.
In the production of epoxy-based materials, Dimethyl-p-toluidine contributes to the cross-linking of the polymer, enhancing its mechanical properties.

Dimethyl-p-toluidine may be used in research and development settings for its catalytic properties in organic synthesis and polymer chemistry.
Dimethyl-p-toluidine is role in facilitating reactions makes it valuable in laboratory-scale studies and applications.
As with many chemical compounds, the disposal of Dimethyl-p-toluidine should be done following appropriate environmental regulations and guidelines.

Dimethyl-p-toluidine is important to consider the potential environmental impact and adhere to responsible disposal practices.
Dimethyl-p-toluidine may be sold under various trade names and synonyms, depending on the manufacturer or supplier.
Dimethyl-p-toluidine should be handled in accordance with safety protocols, and exposure should be minimized.

Dimethyl-p-toluidine is important to use appropriate personal protective equipment (PPE), such as gloves and goggles, when working with this compound.
Adequate ventilation is recommended to avoid inhalation of vapors.
Dimethyl-p-toluidine may be harmful if swallowed, inhaled, or comes in contact with the skin.

Contact with skin or eyes may cause irritation.
Prolonged or repeated exposure may lead to more severe health effects.
Dimethyl-p-toluidine is generally considered toxic, and exposure should be minimized.

In case of contact with skin or eyes, thorough rinsing with water is recommended.
If swallowed or inhaled, seeking medical attention is advised.
First aid procedures should be performed based on the severity and type of exposure.

Melting point: -25°C
Boiling point: 211 °C(lit.)
Density: 0.937 g/mL at 25 °C(lit.)
vapor density: >1 (vs air)
vapor pressure: 0.1 hPa (20 °C)
refractive index: n20/D 1.546(lit.)
Flash point: 182 °F
storage temp.: Store below +30°C.
solubility: 0.65g/l
form: Liquid
pka: pK1:7.24(+1) (25°C)
color: Clear yellow
explosive limit: 7%
Water Solubility: Miscible with alcohol, ether and chloroform. Immiscible with water.
BRN: 774409
Dielectric constant: 3.3（20℃）
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey: GYVGXEWAOAAJEU-UHFFFAOYSA-N
LogP: 1.729-2.81 at 35℃

Dimethyl-p-toluidine neutralizes acids in exothermic reactions to form salts plus water. 
May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. 
May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Dimethyl-p-toluidine used in dental practice are blends of poly(methyl methacrylated) particles and methyl methacrylate monomer, or copolymers of methyl methacrylate with styrene or other acrylic monomers.
This blend is a slurry of high viscosity that is hardened by the free radical polymerization of the monomeric components.
The hardening process is initiated by the decomposition of a small number of organic peroxides (1% to 3%; usually benzoyl peroxide) activated by the redox reaction with the tertiary amine.

The tertiary amine, most often Dimethyl-p-toluidine, is the ingredient that induces the reaction giving rise to free radicals capable of initiating polymerization of the acrylic monomers.
Dimethyl-p-toluidine is used in the following products: pH regulators and water treatment products, adhesives and sealants, leather treatment products and laboratory chemicals. 
Dimethyl-p-toluidine is used in the following areas: health services and scientific research and development.

Dimethyl-p-toluidine is used for the manufacture of: textile, leather or fur. 
Other release to the environment of Dimethyl-p-toluidine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
Dimethyl-p-toluidine is used in the following products: adhesives and sealants.

Release to the environment of Dimethyl-p-toluidine can occur from industrial use: formulation of mixtures.
Dimethyl-p-toluidine is used in the following products: adhesives and sealants, textile treatment products and dyes, pH regulators and water treatment products and laboratory chemicals.
Dimethyl-p-toluidine has an industrial use resulting in manufacture of another substance (use of intermediates).

Dimethyl-p-toluidine is used in the following areas: formulation of mixtures and/or re-packaging, health services and scientific research and development.
Dimethyl-p-toluidine is used for the manufacture of: chemicals.
Dimethyl-p-toluidine is a crucial compound used in synthesis processes. 

With its highly specific composition and exceptional purity, it offers reliable and precise results that meet the demands of various scientific and industrial applications. 
Dimethyl-p-toluidine has a molecular formula of 4-(CH3)C6H4N(CH3)2 and a CAS number of 99-97-8, allowing for easy identification and traceability.
Dimethyl-p-toluidine is colorless or lightyellow liquid, with the rotten egg smell. 

Insoluble in water, soluble in some organic solvents, will decomposition when exposure under the sun.
As an effective photo initiator for the polymerization of acrylonitrile (AN), its polymerization rate is proportional to the 1.62 power of AN concentration and the 0.62 power of Dimethyl-p-toluidine concentration. 
Dimethyl-p-toluidine is usually used as an accelerator, and can also be used as an additive for the synthesis of unsaturated polyesters and adhesives.

Dimethyl-p-toluidine is a chemical that should be handled with care, and exposure should be minimized.
Adequate ventilation and personal protective equipment (PPE) are recommended when working with this compound.
Dimethyl-p-toluidine is important to follow safety guidelines and protocols outlined in safety data sheets (SDS) for specific applications.

Dimethyl-p-toluidine may be subject to regulations and restrictions depending on the region and its intended use. 
Dimethyl-p-toluidine's important to comply with relevant regulatory standards and guidelines.
Dimethyl-p-toluidine should be stored in a cool, dry place away from incompatible materials.

Proper labeling, segregation, and storage procedures should be followed.
Dimethyl-p-toluidine may be subject to regulatory requirements depending on the region and its intended use.
Compliance with local, national, and international regulations is essential.

Emergency response procedures should be in place, and individuals working with Dimethyl-p-toluidine should be trained in handling emergency situations.
Emergency contact information and procedures should be readily available.
Dimethyl-p-toluidine waste should be done following appropriate environmental regulations.

Consultation with waste management experts or authorities is recommended for proper disposal methods.
Transportation of Dimethyl-p-toluidine should comply with relevant transportation regulations.
Packaging and labeling should meet transportation guidelines.

Uses Of Dimethyl-p-toluidine:
Dimethyl-p-toluidine is an amine accelerator for the polymerization of e.g. dental methacrylic restorative materials
Dimethyl-p-toluidine is used as a polymerization catalyst for polyesters, acrylate and epoxy resins. 
Dimethyl-p-toluidine is also used as a hardener for dental cements and in adhesives. 

Dimethyl-p-toluidine serves as an intermediate for photographic chemicals, in industrial glues, in artificial fingernail preparations, colorants, pharmaceuticals. 
Dimethyl-p-toluidine reacts with vinyl ether in the presence of copper(II) chloride gives tetrahydroquinolines. 
Further, Dimethyl-p-toluidine is used to accelerate polymerization of ethyl methacrylate.

Dimethyl-p-toluidine is used as an accelerator in the preparation of dental materials and bone cements to activate the polymerization reaction or when curing methyl methacrylate monomers. 
The concentrations in these preparations are usually between 0.5% and 3% (NTP, 2012). 
Dimethyl-p-toluidine has also been used for the preparation of acrylic denture material for the past 50 years (HSDB, 2015). 

In addition, Dimethyl-p-toluidine is an important ingredient of industrial glues and artificial fingernail preparations, when short setting times are needed, and is also used as an intermediate in the manufacture of dyes and pesticides (NTP, 2012).
Dimethyl-p-toluidine is used to accelerate polymerization of ethyl methacrylate.
Dimethyl-p-toluidine is an accelerator in the redox initiator-accelerator system used commercially to cure methyl methacrylate monomers.

Dimethyl-p-toluidine is a high-production volume chemical with potential for widespread human exposure through its use in dental materials and bone cement.
Dimethyl-p-toluidine has been used in the preparation of acrylic denture materials for the past 50 years.
Dimethyl-p-toluidine is used as the accelerator for the cement in most of the hip and bone replacements to activate the polymerization reaction at concentrations ranging from 0.7% to 2.6% .

Dimethyl-p-toluidine is found in industrial glues and artificial fingernail preparations and is used as an intermediate in dye and pesticide synthesis. 
Dimethyl-p-toluidine has a shorter setting time (11.5 minutes) than some alternative accelerators.
Dimethyl-p-toluidine is an amine accelerator for the polymerization of e.g. dental methacrylic restorative materials.

Dimethyl-p-toluidine is used as a polymerization catalyst for polyesters, acrylate, and epoxy resins.
Dimethyl-p-toluidine is also used as a hardener for dental cement and in adhesives.
Dimethyl-p-toluidine serves as an intermediate for photographic chemicals, in industrial glues, artificial fingernail preparations, colorants, and pharmaceuticals.

Dimethyl-p-toluidine reacts with vinyl ether in the presence of copper(II) chloride giving tetrahydroquinolines.
Further, Dimethyl-p-toluidine is used to accelerate the polymerization of ethyl methacrylate.
Dimethyl-p-toluidine is used to make self-setting tooth tray water.

A tertiary amine that can be C- C coupled with phenylacetylene and benzamide for iron-catalyzed oxidation in the presence of di-tertbutyl peroxide to form N, 4-dimethyl-N-(3-phenyl prop-2-ynyl) phenylazamine and N-((methyl (p-tolyl) amino) methyl) benzamide, respectively.
Dimethyl-p-toluidine is used as a polymerization catalyst for polyesters, acrylate and epoxy resins.
Dimethyl-p-toluidine is also used as a hardener for dental cement and in adhesives.

Dimethyl-p-toluidine serves as an intermediate for photographic chemicals, in industrial glues, in artificial fingernail preparations, colorants, and pharmaceuticals. 
Dimethyl-p-toluidine reacts with vinyl ether in the presence of copper(II) chloride giving tetrahydroquinolines.
Further, Dimethyl-p-toluidine is used to accelerate the polymerization of ethyl methacrylate.

The curing of unsaturated polyester resins at ambient temperatures can in general not be performed by an organic peroxide alone. 
The radical formation, which is necessary to start the polymerisation reaction, is at ambient temperatures with most generally applied organic peroxides too slow.
To speed up the radical formation in a controllable way, organic peroxides must therefore be used in combination with a so-called accelerator

Dimethyl-p-toluidine serves as a valuable reagent in chemical synthesis, especially in the production of dyes, polymers, and specialty chemicals. 
Dimethyl-p-toluidine is versatile nature allows for numerous transformations and reactions.
Dimethyl-p-toluidine plays a crucial role in pharmaceutical research, serving as a catalyst or intermediate in the synthesis of active pharmaceutical ingredients (APIs) and other drug-related compounds.

Dimethyl-p-toluidine finds application in electrochemical processes, such as the synthesis of conductive polymers and batteries. 
Dimethyl-p-toluidine is unique properties contribute to enhanced performance in these applications.
Dimethyl-p-toluidine is utilized in various material science research, including the production of coatings, adhesives, and sealants. 

Dimethyl-p-toluidine contributes to the development of advanced materials with improved properties.
Dimethyl-p-toluidine is often used as a chemical reagent in various chemical reactions and syntheses.
Dimethyl-p-toluidine is employed in the production of certain polymers and plastics.

Dimethyl-p-toluidine is used as a catalyst in the curing of certain types of resins and in the production of polyurethane foams.
In the medical field, it may be used in some dental materials.
Dimethyl-p-toluidine is often used as a catalyst in the polymerization of certain resins, such as epoxy resins. 

Dimethyl-p-toluidine helps initiate and accelerate the curing process, leading to the formation of a solid polymer.
In the manufacturing of polyurethane foams, Dimethyl-p-toluidine serves as a tertiary amine catalyst. 
Dimethyl-p-toluidine facilitates the reaction between isocyanates and polyols, contributing to the formation of polyurethane materials used in foams, coatings, and adhesives.

Dimethyl-p-toluidine is utilized in the formulation of adhesives and sealants. 
Dimethyl-p-toluidine is catalytic properties play a role in cross-linking and curing processes, providing strength and durability to the final product.
Dimethyl-p-toluidine is employed in some dental materials, particularly as a catalyst in the setting of certain dental composites and adhesives.

Dimethyl-p-toluidine is used as a reagent in various chemical syntheses and organic reactions in research and industrial laboratories.
Dimethyl-p-toluidine is involved in the production of certain plastics and resins, contributing to their polymerization and curing processes.
Dimethyl-p-toluidine may be used as a reagent or catalyst in specific procedures and reactions.

Due to its catalytic properties and role in polymer chemistry, Dimethyl-p-toluidine is used in research and development for studying and optimizing polymerization processes.
Dimethyl-p-toluidine is an organic compound that is commonly used in organic synthesis and as a reagent in laboratory experiments. 
Dimethyl-p-toluidine is a colorless, crystalline solid that is soluble in most organic solvents. 

Dimethyl-p-toluidine is also used in the production of pharmaceuticals, agrochemicals, and pesticides. 
Dimethyl-p-toluidine has a wide range of applications in the laboratory and is an important reagent for the synthesis of a variety of compounds.
Dimethyl-p-toluidine is commonly used as a curing agent or accelerator in the polymerization of certain resins, such as those used in the production of epoxy resins and polyurethane foams.

Dimethyl-p-toluidine is utilized in the formulation of adhesives and sealants.
In dentistry, Dimethyl-p-toluidine is employed in some dental materials, particularly as a catalyst in the setting of certain dental composites and adhesives.
Dimethyl-p-toluidine may be used as a reagent in certain analytical procedures and chemical syntheses.

Dimethyl-p-toluidine is employed in the production of certain resins, especially those used in coatings, laminates, and other applications where a durable and cross-linked polymer is desired.
Dimethyl-p-toluidine can be used as a catalyst in processes involving the production of certain synthetic fibers and textiles.
Dimethyl-p-toluidine is sometimes utilized as a photoinitiator in photopolymerization reactions. 

In this context, Dimethyl-p-toluidine helps initiate polymerization reactions when exposed to light.
In the oil and gas industry, Dimethyl-p-toluidine is occasionally used in oil well stimulation processes. 
Dimethyl-p-toluidine may be part of formulations designed to enhance the recovery of oil from reservoirs.

Dimethyl-p-toluidine may find applications in analytical chemistry laboratories as a reagent or catalyst in various chemical reactions and synthesis processes.
Dimethyl-p-toluidine can be used in the production of certain materials, such as encapsulants and coatings, where polymerization and cross-linking are essential for performance and durability.
Dimethyl-p-toluidine may be included in formulations for metal coatings and finishing processes, contributing to the properties of the final coated surfaces.

In the woodworking industry, Dimethyl-p-toluidine can be incorporated into formulations for wood coatings, providing enhanced durability and adhesion.
Dimethyl-p-toluidine may be used in the production of certain adhesive tapes, contributing to the adhesive properties and overall performance of the tapes.
Due to its versatile reactivity, Dimethyl-p-toluidine is employed in chemical research for the synthesis of various organic compounds.

Health Hazard Of Dimethyl-p-toluidine:
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. 
Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. 
Effects of contact or inhalation may be delayed. 

Fire may produce irritating, corrosive and/or toxic gases. 
Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard Of Dimethyl-p-toluidine:
Combustible material: may burn but does not ignite readily. 
When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. 
Contact with metals may evolve flammable hydrogen gas. 

Containers may explode when heated. Runoff may pollute waterways. 
Dimethyl-p-toluidine may be transported in a molten form.