DIMETHYLAMINOPROPYLAMINE

CAS No: 109-55-7

Synonyms:
   N,N-3-dimethyl-1,3-propanediamine; 1-Amino-3-dimethylaminopropane; 3-Aminopropyldimethylamine; N,N-Dimethyl-1,3-diaminopropane; N-,N-Dimethylaminopropylamine; DMAPA;  3-Dimethylaminopropylamine; 109-55-7; 3-(Dimethylamino)propylamine; N,N-DIMETHYL-1,3-PROPANEDIAMINE; 3-(Dimethylamino)-1-propylamine; 1,3-Propanediamine, N,N-dimethyl-; N,N-Dimethyltrimethylenediamine; N,N-dimethylpropane-1,3-diamine; 3-Aminopropyldimethylamine; N,N-Dimethylpropylenediamine; (3-aminopropyl)dimethylamine; 3-(Dimethylamino)-1-propanamine; 1-(Dimethylamino)-3-aminopropane; 3-Amino-1-(dimethylamino)propane; N,N-Dimethyl-1,3-diaminopropane; N-Dimethyltrimethylenediamine; N,N-Dimethyl-1,3-propylenediamine; Dimethylaminopropylamine; N,N-Dimethyl-N-(3-aminopropyl)amine; NSC 1067; UNII-I98I2UEC03; Propylamine, 3-(N,N-dimethylamino)-; 1-Amino-3-dimethylaminopropane; CCRIS 4799; gamma-(Dimethylamino)propylamine; HSDB 5391; 1-Amino-3-(dimethylamino)propane; .gamma.-(Dimethylamino)propylamine; EINECS 203-680-9; 3-AMINO-(DIMETHYLPROPYLAMINE); 1,3-Propanediamine, N1,N1-dimethyl-; BRN 0605293; AI3-25441; I98I2UEC03; 1-Amino-3-dimethylamino propane; IUNMPGNGSSIWFP-UHFFFAOYSA-N; N,N-dimethyl-1,3-propane diamine; N1,N1-dimethylpropane-1,3-diamine; MFCD00008216; DSSTox_CID_5102; DSSTox_RID_77667; DSSTox_GSID_25102; 3-Dimethylaminopropylamine, 99%; CAS-109-55-7; N,N'-Dimethyl-1,3-diaminopropane; 3-dimethylamino propylamine; 3-(dimethylamino)-1-aminopropane; N',N'-dimethylpropane-1,3-diamine; N',N'-Dimethyl propane-1,3-diamine; N,3-propylenediamine; dimethylammo propylamme; dimethyl aminopropylamine; dimethylaminopropyl amine; Dimethylaminopropyl-amine; ACMC-1BRG7; NH2CH2CH2CH2NMe2; 3-dimethylamino-propylamine; 3-dimethylaminopropyl amine; EC 203-680-9; 3-(Dimethyamino)propylamine; Cyclohexyl amineN,N-Dimethyl-1,3-propanediamine; (3-dimethylaminopropyl)amine; 3-dimethylamino-1propylamine; 3-dimethylamino-propyl amine; N,N-dimethyltrimethylendiamin; SCHEMBL30161; 3-dimethylamino-n-propylamine; KSC174K7L; 3-(dimethyl-amino)propylamine; 3-(dimethylamino) propylamine; 3-(dimethylamino)-propylamine; 3-(dimethylamino)propyl amine; 3-dimethylamino-1-propylamine; Propylamine,N-dimethylamino)-; [3-(dimethylamino)propyl]amine; H2NC3H6N(CH3)2; SCHEMBL7633005; 1-amino-3-dimethylamino-propane; 3-(dimethylamino)-n-propylamine; CHEMBL1232234; DTXSID5025102; CTK0H4575; KS-00000WMI; N,N-Dimethy-1,3-propanediamine; WLN: Z3N1&1; N,N-dimethyl-1.3-propanediamine; NSC1067; 3-(N,N-dimethylamino)propylamine; H2N(CH2)3N(CH3)2; 3-(N,N-dimethyl amino)propylamine; 3-(N,N-dimethylamino)-propylamine; N, N-dimethyl-1,3-diaminopropane; N, N-dimethyl-1,3-propanediamine; N,N-dimethyl-1, 3-propanediamine; N,N-Dimethyl-1,3-propane-diamine; N,N-dimethyl-propane-1,3-diamine; 3-Dimethylaminopropylamine (DMAPA)i n',n'-dimethyl-1,3-propanediamine; N,N-Dimethylpropylene-1,3-diamine; N1,N1-dimethylpropan-1,3-diamine; NSC-1067; STR00957; ZINC1587811; N1,N1-dimethyl-1,3-propanediamine; Tox21_202048; Tox21_303328; AC-363; ANW-16063; BBL027699; LS-481; N,N-Di-methyl-3-amino-propyl-amine; SBB028177; STL168867; N',N'-dimethyl-propane-1,3-diamine; N1,N1-dimethyl-propane-1,3-diamine; 3-(Dimethyl-d6-amino)-1-propylamine; 3-(N,N-dimethylamino)-1-propylamine; AKOS000119881; MCULE-9301668058; RTC-020241; TRA0008731; PROPANE,1-AMINO,3-DIMETHYLAMINO; 3-(Dimethylamino)-1-propylamine, 99%; NCGC00249155-01; NCGC00257003-01; NCGC00259597-01; H305; SC-77485; N(1),N(1)-dimethyl-propane-1,3-diamine; TC-020241; D0790; FT-0629498; N(1), N(1)-dimethyl-propane-1,3-diamine; ST45255361; 98705-EP2289890A1; 98705-EP2301928A1; J-002305; J-520165; Q5277328; 3-(Dimethylamino)-1-propylamine, analytical standard; F2187-2249; 3-(Dimethylamino)-1-propylamine, purum, >=98.0% (GC); InChI=1/C5H14N2/c1-7(2)5-3-4-6/h3-6H2,1-2H; DIMETHYLAMINOPROPYLAMINE (DMAPA); dimetil; amino; amin; metil; methyl; dimethyl; propyl; propylamıne; propylamine; propilamin; propil amin; dimethyl amino propyl amine; dimethylamino; dimethylpropyl; dimethylamino; amino propil amin; aminopropilamin; aminopropylamine; amino propyl amine; dimethylpropylamine; methylpropylamine; dmapa; mapa; DİMETİL; AMİNO; AMİN; METİL; METHYL; DİMETHYL; PROPYL; PROPYLAMINE; PROPYLAMİNE; PROPİLAMİN; PROPİL AMİN; DİMETHYL AMİNO PROPYL AMİNE; DİMETHYLAMİNO; DİMETHYLPROPYL; DİMETHYLAMİNO; AMİNO PROPİL AMİN; AMİNOPROPİLAMİN; AMİNOPROPYLAMİNE; AMİNO PROPYL AMİNE; DİMETHYLPROPYLAMİNE; METHYLPROPYLAMİNE; DMAPA; MAPA; dimetilamin; dimetil amin; dimethylamine; dimethyl amine; DİMETİLAMİN; DİMETİL AMİN; DİMETHYLAMİNE; DİMETHYL AMİNE; dimetil amino propil; dimethyl amino propyl; dimethylaminopropyl; dimetilaminopropil; DİMETİL AMİNO PROPİL; DİMETHYL AMİNO PROPYL; DİMETHYLAMİNOPROPYL; DİMETİLAMİNOPROPİL; amin; aminoa, aminometil; aminodimetil; amino dimetil; amino metil; di metil amin; di metilamin; dimetilamin; propil amin; propilamin; di metılamıno proamin; proamine;dimetilaminpropil; dimetikaminpropan; propanol; dimethylaminpropan; di metil amino propanol amin; di metil amino propmanol amino; amino propanol dimetil; amino propanol di metil; metilaminopropanolamin; dimetil; minopropmanolamino; aminopropanoldimetil; aminopropanoldimetil; metil aminopropanol amin; di metil aminopropmanol amino; aminopropanol dimetil; aminopropanol di metil; di-metil; di-methylo amin; di-metiloamino propilamine; di-metilo amino propil amine; di-metiloaminopropilamine; propilodimetil amin; di propil metil amin; di propil metilamin; dipropilmetilamin; metilo diamin propil amin; metil di amin propil amin; diaminopropylamin; diamino propyl amin; amin metil; diamino propylamin; pro-amin; metılamınopropanolamın; dımetıl; mınopropmanolamıno; amınopropanoldımetıl; amınopropanoldımetıl; metıl amınopropanol amın; dı metıl amınopropmanol amıno; amınopropanol dımetıl; amınopropanol dı metıl; dı-metıl; dı-methylo amin; dı-metıloamino propılamıne; di-metılo amıno propıl amine; dı-metıloamınopropılamıne; propılodımetıl amın; dı propıl metıl amın; dı propıl metılamın; dıpropılmetılamın; metılo dıamın propıl amın; metıl dı amın propıl amın; dıamınopropylamın; dıamıno propyl amın; amın metıl; dıamino propylamın; pro-amın; dimetilamiynopropilamiyn; di metil amiynopropil amiyn; methiyl amin propily amin; methiylamin propilyamin; methiyl amino propilyo amin; methiylaminpropilyamin; Dİ METILAMINO PROAMİN; PROAMİNE;DİMETİLAMİNPROPİL; DİMETİKAMİNPROPAN; PROPANOL; DİMETHYLAMİNPROPAN; Dİ METİL AMİNO PROPANOL AMİN; Dİ METİL AMİNO PROPMANOL AMİNO; AMİNO PROPANOL DİMETİL; AMİNO PROPANOL Dİ METİL; METİLAMİNOPROPANOLAMİN; DİMETİL; MİNOPROPMANOLAMİNO; AMİNOPROPANOLDİMETİL; AMİNOPROPANOLDİMETİL; METİL AMİNOPROPANOL AMİN; Dİ METİL AMİNOPROPMANOL AMİNO; AMİNOPROPANOL DİMETİL; AMİNOPROPANOL Dİ METİL; Dİ-METİL; Dİ-METHYLO AMİN; Dİ-METİLOAMİNO PROPİLAMİNE; Dİ-METİLO AMİNO PROPİL AMİNE; Dİ-METİLOAMİNOPROPİLAMİNE; PROPİLODİMETİL AMİN; Dİ PROPİL METİL AMİN; Dİ PROPİL METİLAMİN; DİPROPİLMETİLAMİN; METİLO DİAMİN PROPİL AMİN; METİL Dİ AMİN PROPİL AMİN; DİAMİNOPROPYLAMİN; DİAMİNO PROPYL AMİN; AMİN METİL; DİAMİNO PROPYLAMİN; PRO-AMİN; METILAMINOPROPANOLAMIN; DIMETIL; MINOPROPMANOLAMINO; AMINOPROPANOLDIMETIL; AMINOPROPANOLDIMETIL; METIL AMINOPROPANOL AMIN; DI METIL AMINOPROPMANOL AMINO; AMINOPROPANOL DIMETIL; AMINOPROPANOL DI METIL; DI-METIL; DI-METHYLO AMİN; DI-METILOAMİNO PROPILAMINE; Dİ-METILO AMINO PROPIL AMİNE; DI-METILOAMINOPROPILAMINE; PROPILODIMETIL AMIN; DI PROPIL METIL AMIN; DI PROPIL METILAMIN; DIPROPILMETILAMIN; METILO DIAMIN PROPIL AMIN; METIL DI AMIN PROPIL AMIN; DIAMINOPROPYLAMIN; DIAMINO PROPYL AMIN; AMIN METIL; DIAMİNO PROPYLAMIN; PRO-AMIN; DİMETİLAMİYNOPROPİLAMİYN; Dİ METİL AMİYNOPROPİL AMİYN; METHİYL AMİN PROPİLY AMİN; METHİYLAMİN PROPİLYAMİN; METHİYL AMİNO PROPİLYO AMİN; METHİYLAMİNPROPİLYAMİN; metilaminopropilamin; metilo aminopropilamin; metil aminpropilamin; metil amin propiyl amin; METİLAMİNOPROPİLAMİN; METİLO AMİNOPROPİLAMİN; METİL AMİNPROPİLAMİN; METİL AMİN PROPİYL AMİN

DIMETHYLAMINOPROPYLAMINE (DMAPA)

Dimethylaminopropylamine

Not to be confused with N,N′-Dimethyl-1,3-propanediamine.
Dimethylaminopropylamine
Skeletal formula of dimethylaminopropylamine
Names
Preferred IUPAC name
N1,N1-dimethylpropane-1,3-diamine
Systematic IUPAC name
N,N-Dimethyl-1,3-diaminopropane
Other names
3-(Dimethylamino)-1-propylamine
3-Dimethylaminopropylamine
N,N-Dimethyl-1,3-propanediamine
Identifiers
CAS Number    
109-55-7 check
3D model (JSmol)    
Interactive image
ChEMBL    
ChEMBL1232234 ☒
ChemSpider    
7703 check
ECHA InfoCard    100.003.347 
EC Number    
203-680-9
MeSH    3-dimethylaminopropylamine
PubChem CID    
7993
RTECS number    
TX7525000
UNII    
I98I2UEC03 check
UN number    2733
CompTox Dashboard (EPA)    
DTXSID5025102 
InChI[show]
SMILES[show]
Properties of Dimethylaminopropylamine:
Chemical formula of Dimethylaminopropylamine:    C5H14N2
Molar mass of Dimethylaminopropylamine:102.181 g·mol−1
Appearance of Dimethylaminopropylamine:    Colourless liquid
Odor of Dimethylaminopropylamine:    fishy, ammoniacal
Density of Dimethylaminopropylamine:    812 mg mL−1
Boiling point of Dimethylaminopropylamine:    132.1 °C; 269.7 °F; 405.2 K
log P of Dimethylaminopropylamine:    −0.211
Vapor pressure of Dimethylaminopropylamine:    0.7–2.4 kPa
Refractive index  of Dimethylaminopropylamine:(nD)    1.435–1.436
Thermochemistry of Dimethylaminopropylamine:
Heat capacity (C) of Dimethylaminopropylamine:    255.7 J K−1 mol−1
Std molar of Dimethylaminopropylamine:
entropy (So298) of Dimethylaminopropylamine:    323.0 J K−1 mol−1
Std enthalpy of
formation (ΔfH⦵298)    −76.9–−76.9 kJ mol−1
Std enthalpy of
combustion (ΔcH⦵298)    −3.8955–−3.8875 MJ mol−1
Hazards
GHS pictograms    GHS02: Flammable GHS05: Corrosive GHS07: Harmful
GHS Signal word    Danger
GHS hazard statements    H226, H302, H314, H317
GHS precautionary statements    P280, P305+351+338, P310
Flash point of Dimethylaminopropylamine:    32 °C (90 °F; 305 K)
Explosive limits    2.3–12.36%
Lethal dose or concentration (LD, LC):
LD50 (median dose)    
487 mg kg−1 (dermal, rabbit)
1.87 g kg−1 (oral, rat)
Related compounds
Related amines    
Dimethylamine
Trimethylamine
N-Nitrosodimethylamine
Diethylamine
Triethylamine
Diisopropylamine
Diethylenetriamine
N,N-Diisopropylethylamine
Triisopropylamine
Tris(2-aminoethyl)amine
Mechlorethamine
HN1 (nitrogen mustard)
HN3 (nitrogen mustard)
Related compounds    
Unsymmetrical dimethylhydrazine
Biguanide
Dithiobiuret
Agmatine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒ verify (what is check☒ ?)
Infobox references
Dimethylaminopropylamine (DMAPA) is a diamine used in the preparation of some surfactants, such as cocamidopropyl betaine which is an ingredient in many personal care products including soaps, shampoos, and cosmetics. BASF, a major producer, claims that DMAPA-derivatives do not sting the eyes and makes a fine-bubble foam, making it appropriate in shampoos.[1]

Preparation and reactions
Dimethylaminopropylamineis commonly produced commercially via the reaction between dimethylamine and acrylonitrile (a Michael reaction) to produce dimethylaminopropionitrile. A subsequent hydrogenation step yields DMAPA:[2]

Manufacture of DMAPA.png
Dimethylaminopropylamineis readily converted to the mustard dimethylaminopropyl-3-chloride, a powerful alkylating agent.[3]

Health effects
Dimethylaminopropylamine is a known skin irritant and its presence as an impurity in cocamidopropyl betaine is thought to be the cause of irritation experienced by some individuals.[4][5]

See also
1,1-Dimethylethylenediamine
1,2-Dimethylethylenediamine

Chemical synonyms:    N,N-3-dimethyl-1,3-propanediamine; 1-Amino-3-dimethylaminopropane; 3-Aminopropyldimethylamine; N,N-Dimethyl-1,3-diaminopropane; N-,N-Dimethylaminopropylamine; DMAPA
Product description
Dimethylaminopropylamineis a clear colorless liquid, free of suspended matter.
Dimethylaminopropylamineis completely miscible with water, alcohols, esters and ketones. It has limited miscibility with diethylether, benzene, and chlorinated hydrocarbons.

Dimethylaminopropylamineis either used on itself or as an intermediate in the production of:

Surfactants
Water treatment chemicals
Ion exchange resins
Polyurethane catalysts
Epoxy resin hardeners
Corrosion inhibitors
Gasoline and motor additives / lubricating oil additives
Textile auxiliaries
Agrochemicals
Pharmaceuticals
Paper adjuvants
Photographic adjuvants

Applications/uses
Cosmetic and personal care intermediate
Fabric care
Hard surface care
Home & industrial care intermediates
Soap/detergents
 
dimethylaminopropylamine (dmapa)
Where is dimethylaminopropylamine (dmapa) found?
Dimethylaminopropylamine is found in personal care products such as fabric softeners, liquid soaps, shampoos, and dyes. Leather, paper, and rubber industries also use this substance.
How can you avoid contact with dimethylaminopropylamine (dmapa)?
Avoid products that list any of the following names in the ingredients:

• 1,3-Propanediamine, N,N-dimethyl-
• 1-(Dimethylamino)-3-aminopropane
• 1-Amino-3-dimethylaminopropane
• 3-(Dimethylamino)-1-propanamine
• 3-(Dimethylamino)-1-propylamine
• 3-(Dimethylamino)propylamine
• 3-Amino-1-(dimethylamino)propane
• 4-04-00-01259 (Beilstein Handbook Reference)
• AI3-25441
• BRN 0605293
• CCRIS 4799
• EINECS 203-680-9
• HSDB 5391
• N,N-Dimethyl-1,3-diaminopropane
• N,N-Dimethyl-1,3-propanediamine
• N,N-Dimethyl-1,3-propylenediamine
• N,N-Dimethyl-N-(3-aminopropyl)amine
• N,N-Dimethylpropylenediamine
• N,N-Dimethyltrimethylenediamine
• N-Dimethyltrimethylenediamine
• NSC 1067
• Propylamine, 3-(N,N-dimethylamino)-
• gamma-(Dimethylamino)propylamin

What are some products that may contain dimethylaminopropylamine (dmapa)?
Clothing
• Leather
• Rubber
Hair Care
• Hair coloring
• Shampoos

Dimethylaminopropylamine has been used for preparing good corrosion inhibitors (amine phosphates) for aviation gasoline. Heating Dimethylaminopropylamineand urea yields a product which is useful as an octane requirement reducer.

Dimethylaminopropylamine has been used effectively for curing epoxy resins.

Derivatives of dimethylaminopropylamine have been examined in pharmaceutical applications. Diquaternary salts of Dimethylaminopropylaminederivatives have been suggested for regulating blood pressure.

Dimethylaminopropylamine as the undiluted product is severely irritating to the eyes, skin, and mucous membranes of exposed individuals. Adequate eye and skin protection must be provided; chemical goggles with full face shield, protective clothing, and impervious gloves must be worn during handling of dimethylaminopropylamine. In case of contact, flush eyes immediately with water for at least 15 minutes, then get medical attention.

Carbon steel is a satisfactory material for storing and handling dimethylaminopropylamine. Copper, zinc, lead, or alloys containing any of these materials should not be used, since they will be attacked by the product.Carbon steel is acceptable for transfer lines. Lines should be blown or drained clean after each use. NA75: Dimethylaminopropylamine (DMAPA)

Otherwise, the product will discolor when it is left in the lines for an extended period. In cases where it is impossible to drain lines, or where the dimethylaminopropylamine is handled warm, stainless steel will be required. Since the product will leach coventional pipe dopes from threaded connections, the lines should be welded or flanged.

Dimethylaminopropylamine is a flammable material; therefore, care should be taken in handling and storage. It should be stored away from heat and open flame. It is also a corrosive material; therefore, care should be taken to avoid contact with the product.

Dimethylaminopropylamine (DMAPA) came to the attention of the National Cancer Institute (NCI) Division of Cancer Biology as the result of a review of chemical industry information suggesting an increased production or use of this chemical.

DIMETHYLAMINOPROPYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Dimethylaminopropylamine (DMAPA) is a clear, essentially colorless liquid with a typical amine odor. It is completely soluble in water, benzene, heptane, and other organic solvents.

Dimethylaminopropylamine supply requirements and can ship bulk and various packaged products to meet such needs.

Dimethylaminopropylamine is widely used in the manufacture of cosmetic raw materials such as palmitamide dimethyl propylamine, cocamidopropyl betaine, oleose amide propylamine

Dimethylaminopropylamine (DMAPA) is a colorless to yellow liquid and moderately basic compound having amine like odour. It is miscible in water and most common organic solvents like alcohol and esters among the others. Dimethylaminopropylamine is significantly used in the formulation of personal care products like liquid soaps, shampoos, hair conditioners, hair colors, liquid hand wash, fabric softeners, foam boosters and sun protection agents among the others. Dimethylaminopropylamine also finds applications such as surfactants, corrosion inhibitors, anti-static agents, emulsifiers, gasoline additives and flocculating agents inclusive of others. Dimethylaminopropylamine is used as an intermediate in the production of pharmaceuticals, dyes, agrochemicals and paper adjuvants etc. Dimethylaminopropylamine (DMAPA) is also used in water treatment solutions. The derivatives of Dimethylaminopropylamineare used as viscosity index improvers and dispersants in lubricants.

The major application of Dimethylaminopropylamine (DMAPA) include its use as a catalyst in the production of polyurethane foam. Thus extensive use of polyurethane foam is in bedding, interiors of cars, furniture and footwear among the others. The increasing demand for polyurethane foams is likely to result in an increase in demand for Dimethylaminopropylamine (DMAPA). Thus, in turn, driving the growth of the global Dimethylaminopropylamine (DMAPA) market during the forecast period. The rising demand for personal care products is expected to drive the growth of global Dimethylaminopropylamine (DMAPA) market, because of the use of Dimethylaminopropylamine (DMAPA) as a surfactant in personal care products. On the other hand, exposure to Dimethylaminopropylamine during manufacturing process in which it is used as raw material or as an intermediate, is found to result in allergies related to skin. Also, Dimethylaminopropylamineas an impurity in personal care products results in allergies to skin. Thus, concerns as regards the ill-effects on health arising due to the use of DMAPA, are expected to be major challenge to growth of the global Dimethylaminopropylamine (DMAPA) market during the forecast period.

global Dimethylaminopropylamine (DMAPA) market is segmented into seven geographical regions namely North America, Latin America, Western Europe, Eastern Europe, Middle East & Africa, Asia-Pacific (excluding Japan) and Japan. The Asia-Pacific and Japan region are expected to witness relatively faster growth as compared to other regions of the globe during the forecast period due to consumption and increasing demand for personal care products and polyurethane foams. Asia-Pacific is expected to be followed by North America and Europe. The growth in these regions are relatively slower as compared to the growth of Asia-Pacific region. The Dimethylaminopropylamine (DMAPA) market is also expected to witness a steady growth in Latin America. The increasing demand for personal care products due to changing lifestyle is likely to result in increase in demand for Dimethylaminopropylamineduring the forecast period.

Your patch test result indicates that you have a contact allergy to dimethylaminopropylamine This contact allergy may cause your skin to react when it is exposed to this substance although it may take several days for the symptoms to appear.
Where is dimethylaminopropylamine found? Dimethylaminopropylamine is found in personal care products such as fabric softeners, liquid soaps, shampoos, and dyes. Leather, paper, and rubber industries also use this substance.

As shown in Fig. 1 , CAPB is synthesized by reacting fatty acids, often obtained from coconut oil, or coconut oil, with dimethylaminopropylamine (DMAPA), yielding lauramidopropyldimethylamine (LAPDMA) [1]. LAPDMA is subsequently allowed to react with sodium monochloroacetate to produce the end product CAPB.

Shampoos, but, nevertheless, serves to confirm that the hazard with CAPB exists. However, over a number of years, work has repeatedly indicated that CAPB is not actually the allergen, but it is in reality two 'impurities', dimethylaminopropylamine and cocoamidoamine, which are responsible. These impurities are in fact a starting material and a manufacturing intermediate, respectively.

Dimethylaminopropylamine (DMAPA) is a clear liquid with mildly basic nature. It is soluble in common organic solvents. Dimethylaminopropylamineis primarily used as an intermediate in the manufacture of various amphoteric surfactants; the most important ones are amine oxide and betaine. Cocamidopropyl betaine, a co-surfactant derived from Dimethylaminopropylamineand coconut oil based lauric acid, is used in shampoos, shower gels and liquid soaps. Personal care products with substances derived from Dimethylaminopropylamineare mild on the skin and do not hurt the eyes.

The Global Market for dimethylaminopropylamine (DMAPA) detailed coverage of dimethylaminopropylamine industry and presents main market trends. The market research gives historical and forecast market size, demand and production forecasts, end-use demand details, price trends, and company shares of the leading dimethylaminopropylamine producers to provide exhaustive coverage of the dimethylaminopropylamine.

Analysis of the dimethylaminopropylamine market including revenues, future growth, market outlook.

Profiles on dimethylaminopropylamine including products, sales/revenues, and market position.

Dimethylaminopropylamine (DMAPA) is a diamine produced by reacting dimethylamine and acrylonitrile, followed by hydrogenation process which yields DMAPA. It is a clear, colorless liquid completely miscible
with water, alcohols, esters, and ketones; and partially miscible with diethyl ether, benzene, chlorinated hydrocarbons. It is widely used in producing surfactants which are further used in numerous personal care products such as soaps, shampoos, and cosmetics. It can also be used as a chemical intermediate in the production of water treatment chemicals, ion exchange resins, polyurethane catalysts, epoxy resin hardeners, corrosion inhibitors, agrochemicals, pharmaceuticals, and gasoline.

Europe is projected to be a prominent market for dimethylaminopropylamine on account of the growing demand for premium skin and hair care products. In addition, growing water treatment industry with increasing regulations against wastewater discharge is likely to drive the market growth.

The North American dimethylaminopropylamine (DMAPA) market is expected to record significant growth during the review period. Expanding construction industry with rise in residential construction activity is expected to support the market growth.

The Latin American dimethylaminopropylamine (DMAPA) market is expected to exhibit considerable growth with respect to the growing construction industry, especially in Brazil and Mexico. The dimethylaminopropylamine (DMAPA) market in the Middle East & Africa is likely to show moderate growth during the review period with growing end use industries such as personal care & cosmetics and construction.

The global dimethylaminopropylamine market has been segmented based on application and region.

Based on application, the global dimethylaminopropylamine (DMAPA) market has been categorized into cosmetics & personal care, PU catalyst, pharmaceuticals, lubricant additives, water treatment, resins, agrochemicals, and others.

Formula: C5H14N2CAS: 109-55-7Description: Dimethylaminopropylamine (Dimethylaminopropylamine) is a colorless to yellow liquid, with an amine-like odor. It is miscible in water.Synonyms: DMAPA, 3-(Dimethylamino)propylamine, Dimethylaminopropylamine, N,N-Dimethyl-1,3-propanamin, 1-(dimethylamino)-3-aminopropane, N,N-Dimethyl-1,3-diaminopropane, N,N-Dimethyl-1,3-propylenediamine.

Dimethylaminopropylamine is a compound that is basic in nature; it is a liquid that is colorless or slightly yellow in color and has the odor that is amine like. It can get mixed in water and other solvents such as esters and alcohol. It is used in the manufacturing of the products such as shampoos, hair colors, fabric softeners, sun protection agents, liquid soaps, hair conditioners, liquid hand wash, foam boosters, and others. The other applications where the dimethylaminopropylamine is used include corrosion inhibitors, emulsifiers, flocculating agents, surfactants, anti-static agents, and gasoline additives.

The global dimethylaminopropylamine market is segmented into its application and regions. On the basis of application, the global market is segregated into personal care, water treatment, pharmaceuticals, corrosion inhibitor, textile, PU catalyst, agriculture, fuel additive, dyes, and coating compositions. Region wise the market is diversified into Asia-Pacific, Europe, North America, and Rest of the World.

The growing demand for the dimethylaminopropylamine (DMAPA) in the different applications is the key factor that is driving the growth of the market. Dimethylaminopropylamineis used as catalyst in the production of the polyurethane foams, which are used in the seating systems of the automobiles. The polyurethane foams are used in furniture, insulated windows, bedding, roof & wall insulation, and air barrier sealants. The rise in the demand for the polyurethane foams is driving the demand of the dimethylaminopropylamine. The dimethylaminopropylamine is used in agricultural chemicals, dye intermediates, fabric softeners, antistatic agents, and epoxy curing agents. They are also used in the manufacture of shampoos, fabric softeners, bath oils, bubble baths, soaps, cosmetics, liquid soaps, and moisturizers.

Dimethylaminopropylamine Quick Details

Chemical Name: 3-Dimethylaminopropylamine; CAS No.: 109-55-7; Molecular Fomula:C5H14N2; Molecular weight: 102.18; Appearance: Colorless Transparent Liquid Purity: 99.0%.

Dimethylaminopropylamine (DMAPA) Synonym: DMAPA, Dimethylaminopropylamine, CAS: 109-55-7, 3-Dimethylaminopropylamine CAS: 109-55-7 Dimethylaminopropylamine (DMAPA) is a moderately basic, colorless liquid. The material has a characteristic amine odor and tends to darken on standing. Dimethylaminopropylamineis miscible with water and most common organic solvents. 1, Dimethylaminopropylamine Properties: Molecular formula: C5H14N2 Molecular weight: 102.18 Melting point:-60 Boiling point: 133 Specific gravity D : 0.812 2, Dimethylaminopropylamine Specifications: 3, Dimethylaminopropylamine Uses: • Agricultural Chemicals • Amphoteric surfactants • Anti-static agents • Dyestuff

The 2D chemical structure image of 3-Dimethylaminopropylamine is also called skeletal formula, which is the standard notation for organic molecules. The carbon atoms in the chemical structure of 3-Dimethylaminopropylamine are implied to be located at the corner(s) and hydrogen atoms attached to carbon atoms are not indicated - each carbon atom is considered to be associated with enough hydrogen atoms to provide the carbon atom with four bonds.

The 3D chemical structure image of 3-Dimethylaminopropylamine is based on the ball-and-stick model which displays both the three-dimensional position of the atoms and the bonds between them. The radius of the spheres is therefore smaller than the rod lengths in order to provide a clearer view of the atoms and bonds throughout the chemical structure model of 3-Dimethylaminopropylamine.

Dimethylaminopropylamine molecule shown in the visualization screen can be rotated interactively by keep clicking and moving the mouse button. Mouse wheel zoom is available as well - the size of the 3-Dimethylaminopropylamine molecule can be increased or decreased by scrolling the mouse wheel.

The information of the atoms, bonds, connectivity and coordinates included in the chemical structure of 3-Dimethylaminopropylamine can easily be identified by this visualization. By right-clicking the visualization screen, various other options are available including the visualization of van der Waals surface and exporting to a image file.

It has been discovered that all individuals who are allergic to cocamidopropyl betaine (CAPB) are sensitized to 3-dimethylaminopropylamine (DMAPA) and to amidoamine, molecules which are intermediaries in CAPB synthesis, and which persist as impurities in the material that is sold; the amounts vary, depending on the quality of the CAPB in the end product.

Dimethylaminopropylamine is a diamine generally used for the preparation of some surfactants, such as Cocamidopropyl betaine which is an ingredient in many personal care products including soaps, shampoos, and cosmetics. Dimethylaminopropylamine is a cThe major application of Dimethylaminopropylamine includes its use as a catalyst in the production of polyurethane foam. Thus wide use of polyurethane foam is in bedding, interiors of cars, furniture and footwear among the others. The increasing demand for polyurethane foams is likely to result in an increase in demand for DMAPA. Thus, in turn, driving the growth of the global Dimethylaminopropylamine market during the forecast period.olourless to yellow liquid and the moderately basic compound having an amine-like odour.

On the other hand, Dimethylaminopropylamine is used as a raw material in various products. If DMAPA is exposure during the manufacturing process is found to result in allergies related to skin. Also, Dimethylaminopropylamineas an impurity in personal care products results in allergies to the skin. So that challenge to grow of the global Dimethylaminopropylaminemarket during the forecast period.

Geographically, the Asia-Pacific region leads the global Dimethylaminopropylamine market. The factors that attributed to the market growth in this region are the changing lifestyle of the people, the rise in disposable incomes, and the increase in the demand for personal care products.

The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the safety of fatty acid amidopropyl dimethylamines, which function primarily as antistatic agents in cosmetic products. The relevant animal and human data reviewed for these ingredients indicate that they are potential dermal sensitizers that may be due in part by the sensitizing impurity, 3,3-dimethylaminopropylamine. The Panel concluded that fatty acid amidopropyl dimethylamines were safe as cosmetic ingredients when they are formulated to be nonsensitizing, which may be based on a quantitative risk assessment.

-DIMETHYLAMINOPROPYLAMINE (DMAPA)
Properties          Application Areas
 

Appearance of Dimethylaminopropylamine: Clear and colourless liquid.
Physical Properties of Dimethylaminopropylamine:    
Empirical Formula of Dimethylaminopropylamine:    C5H14N2
Structural Formula of Dimethylaminopropylamine:    [Structural-Formula]
Molecular Wt. of Dimethylaminopropylamine:    102.2
Sp. Gr. at 20ºC of Dimethylaminopropylamine:    0.81 - 0.82
Refractive Index 20°C of Dimethylaminopropylamine:    1.434 - 1.436
Boiling Point of Dimethylaminopropylamine:    132 to 135°C
Freezing Point of Dimethylaminopropylamine:    below - 60°C
Solubility  of Dimethylaminopropylamine in water    Soluble
Flash Point (Closed Cup) of Dimethylaminopropylamine:    32 - 35°C
Specifications of Dimethylaminopropylamine:
Purity by GC (FID) % of Dimethylaminopropylamine:    99.5% min.
Water by K.F. (wt. %) of Dimethylaminopropylamine:    0.5% max.
Other Amine by GC (wt. %) of Dimethylaminopropylamine:    0.5% max.
IMDG Class of Dimethylaminopropylamine:
8
UN Code No. of Dimethylaminopropylamine:    2734
Packing Group of Dimethylaminopropylamine:    II
CAS No. of Dimethylaminopropylamine:    109-55-7

Dimethylaminopropylamine (DMAPA)
CAS: 109-55-7
Dimethylaminopropylamine (DMAPA) is a clear, essentially colorless liquid with a typical amine odor. Dimethylaminopropylamine is completely soluble in water, benzene, heptane, and other organic solvents.

Dimethylaminopropylamine has applications in leather processing, paper, rubber, and personal care products. Dimethylaminopropylamine is also used as an intermediate in the production of fabric softeners, polymers, agrochemicals, flocculating agents, liquid soaps, and dye intermediates.