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DIOCTYL SEBACATE (DOS)

Dioctyl Sebacate(DOS) is used as a plasticizer for PVC, nitrocelluloses, styrene resins, and synthetic rubbers where low temperature performance is required. DOS is also compliant with FDA CFR 21 for food contact materials. Dioctyl Sebacate can also be used in lubricants to allow more mobility at lower temperatures. DOS can be used as anti-frosting cable, artificial leather, outdoor cable, PVC linoleum, resins and synthetic rubbers. Dioctyl Sebacate provides a silky feel and spreads easily. Because of this, Dioctyl Sebacate finds use in the personal care industry and is found in deodorants and antiperspirants, makeup, skin conditioners, lotions, and sunscreens.

CAS No.: 122-62-3
EC No.: 204-558-8

Synonyms:
Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Di-n-octyl sebacate; 2432-87-3; Dioctyl decanedioate; Decanedioic acid, dioctyl ester; Witamol 500; Sebacic acid, dioctyl ester; UNII-CG4EO6A0O2; Sebacic Acid Dioctyl Ester; Sebacic Acid Di-n-octyl Ester; CG4EO6A0O2; EINECS 219-411-3; Sebacic acid dioctyl; Di-n-octyl Decanedioate; ACMC-1BRIJ; DSSTox_CID_27537; DSSTox_RID_82403; DSSTox_GSID_47537; SCHEMBL37168; Dioctyl sebacate, AldrichCPR; decanedioic acid dioctyl ester; KSC489S8L; CHEMBL3187412; DTXSID0047537; CTK3I9985; Decanedioic Acid Di-n-octyl Ester; NSC16205; Tox21_300523; ANW-20889; MFCD00059269; NSC-16205; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); ZINC59479204; AKOS015839870; NCGC00248083-01; NCGC00254334-01; CAS-2432-87-3; AB0012120; FT-0688072; S0028; K-4644; J-524238; Q27275447; BIS(2-ETHYLHEXYL) SEBACATE; 122-62-3; Bis(2-ethylhexyl) decanedioate; Di(2-ethylhexyl) sebacate; Bisoflex; Plexol; Bisoflex DOS; Monoplex DOS; Octoil S; Decanedioic acid, bis(2-ethylhexyl) ester; Reolube DOS; Staflex DOS; diethylhexyl sebacate; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Uniflex dos; 2-Ethylhexyl sebacate; Edenol 888; Plexol 201J; Sansocizer DOS; Ergoplast SDO; Reomol DDS; Edenor DEHS; Sebacic acid, bis(2-ethylhexyl) ester; Sebacic acid bis(2-ethylhexyl) ester; Di(2-ethylhexyl)sebacate; Di-2-ethylhexyl sebacate; PX 438; 1-Hexanol, 2-ethyl-, sebacate; UNII-U9LS47Q72Q; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); NSC 68878; Bis(ethylhexyl) sebacate, MFCD00009497; Decanedioic acid, 1,10-bis(2-ethylhexyl) ester; DOS; Sebacic acid, bis(2-ethylhexyl)ester; Bis-(2-ethylhexyl)ester kyseliny sebakove; U9LS47Q72Q; decanedioic acid bis(2-ethylhexyl) ester; Bis(2-ethylhexyl) sebacate, 97%; Dioctyl sebacate (VAN); USAF KE-2; Di-2-ethylhexyl isosebacate; CCRIS 6191; HSDB 2898; EINECS 204-558-8; Sebacic acid, di-2-ethylhexyl diester; Isosebacic acid, di-2-ethylhexyl ester; BRN 1806504; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Bis(2-ethylhexyl)decanedioate, AI3-09124; Ergoplast SNO; Plasthall DOS; Bis-(2-ethylhexyl)ester kyseliny sebakove [Czech]; Sebacic acid di(2-ethylhexyl) ester; BEHS; 1-Hexanol, sebacate; Plexol 201; ACMC-209ali; bis(2_ethylhexyl)sebacate; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); DSSTox_CID_5055; EC 204-558-8; DSSTox_RID_77644; DSSTox_GSID_25055, SCHEMBL37169, 4-02-00-02083 (Beilstein Handbook Reference); KSC909K1N; Sebacic acid bis(2-ethylhexyl); CHEMBL3187356; DTXSID7025055; CTK8A9516; NSC68878; Tox21_303439; ANW-18004; NSC-68878; AKOS015903925; Bis(2-ethylhexyl) ester, sebacic acid; MCULE-4334197745; decanedioic acid bis(2_ethylhexyl) ester; NCGC00257416-01; 29590-28-1; CAS-122-62-3; SC-47142; Decanedioic acid, di-(2-ethylhexyl) ester; Bis(2-ethylhexyl) ester, decanedionic acid; DB-041675; FT-0631704; S0025; WLN: 4Y2 & 1OV8VO1Y4 & 2; SEBACIC ACID BIS (2_ETHYLHEXYL) ESTER; Sebacic acid, bis(2-ethylhexyl) ester (8CI); Bis(2-ethylhexyl) sebacate, >=97.0% (GC); Bis(2-ethylhexyl) sebacate, technical grade, 90%; J-004836; Q4387284; Bis(2-ethylhexyl) sebacate, Selectophore(TM), >=97.0%; di(2-ethylhexyl) sebacate, Sebacic acid di(2-ethylhexyl) ester, Bis(2-Ethylhexyl) decanedioate, Dioctyl Sebacate, 1-Hexanol, 2-ethyl-, sebacate, 2-Ethylhexyl sebacate, Bisoflex DOS, Decanedioic acid, bis(2-ethylhexyl)ester, Di(2-ethylhexyl) sebacate, Monoplex DOS, Octoil S, Octyl sebacate, Staflex DOS; bisoflex; bisoflex DOS; decane dioic acid bis(2-ethyl hexyl) ester; decanedioic acid bis(2-ethylhexyl) ester; decanedioic acid di(2-ethylhexyl) ester; decanedioic acid, bis(2-ethylhexyl) ester; di-2-ethylhexyl sebacate; di(2-ethyl hexyl) sebacate; di(2-ethylhexyl) sebacate; di(2-ethylhexyl)sebacate; di2-ethylhexyl decane-1,10-dioate; diethyl hexyl sebacate; diethylhexyl sebacate; dioctyl sebacate; dub green DOS; edenol 888; edenor dehs; ergoplast SDO; bis(2-ethyl hexyl) decane dioate; (±)-bis(2-ethyl hexyl) sebacate; 2-ethylhexyl sebacate; bis(2-ethylhexyl) decanedioate; (±)-bis(2-ethylhexyl) sebacate; bis(ethylhexyl) sebacate; bis(2-ethylhexyl) sebacate; hallstar DOS; monoplex DOS; octoil S; plexol; plexol 201; plexol 201J; ransocizer DOS; reolube DOS; reomol DDS; sansocizer DOS; sebacic acid bis(2-ethyl hexyl) ester; sebacic acid bis(2-ethylhexyl) ester; sebacic acid di(2-ethylhexyl) ester; sebacic acid, bis(2-ethylhexyl) ester; sebacic acid, bis(2-ethylhexyl) ester (8CI); sebacic acid, bis(2-ethylhexyl)ester; sebacic acid, di-2-ethylhexyl diester; staflex DOS; uniflex DOS; uniplex DOS; 219-411-3 [EINECS]; 2432-87-3 [RN]; CG4EO6A0O2; Decanedioic acid dioctyl ester; Decanedioic acid, dioctyl ester [ACD/Index Name]; Di-n-octyl Sebacate; dioctyl decanedioate, Dioctyl sebacate [ACD/IUPAC Name] [Wiki]; Dioctylsebacat [German] [ACD/IUPAC Name]; MFCD00059269; Octyl sebacate; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Sébacate de dioctyle [French] [ACD/IUPAC Name]; Sebacic acid, dioctyl ester; 14491-66-8 [RN]; 27214-90-0 [RN]; decadioic acid, dioctyl ester; Decanedioic acid, diisooctyl ester; Decanedioic acid,1,10-dioctyl ester; DEHS; Di-n-OctylSebacate; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); DOS; Monoplex DOS; Octoil S; Plexol 201; QA-7926; sebacic acid dioctyl ester; SEBACICACIDDI-N-OCTYLESTER; Staflex DOS; U niflex DOS; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); UNII:CG4EO6A0O2; UNII-CG4EO6A0O2; Witamol 500; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Di-n-octyl sebacate; 2432-87-3; Dioctyl decanedioate; Decanedioic acid, dioctyl ester; Witamol 500; Sebacic acid, dioctyl ester; UNII-CG4EO6A0O2; Sebacic Acid Dioctyl Ester; Sebacic Acid Di-n-octyl Ester; CG4EO6A0O2; EINECS 219-411-3; Sebacic acid dioctyl; Di-n-octyl Decanedioate; ACMC-1BRIJ; DSSTox_CID_27537; DSSTox_RID_82403; DSSTox_GSID_47537; SCHEMBL37168; Dioctyl sebacate, AldrichCPR; decanedioic acid dioctyl ester; KSC489S8L; CHEMBL3187412; DTXSID0047537; CTK3I9985; Decanedioic Acid Di-n-octyl Ester; NSC16205; Tox21_300523; ANW-20889; MFCD00059269; NSC-16205; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); ZINC59479204; AKOS015839870; NCGC00248083-01; NCGC00254334-01; CAS-2432-87-3; AB0012120; FT-0688072; S0028; K-4644; J-524238; Q27275447; BIS(2-ETHYLHEXYL) SEBACATE; 122-62-3; Bis(2-ethylhexyl) decanedioate; Di(2-ethylhexyl) sebacate; Bisoflex; Plexol; Bisoflex DOS; Monoplex DOS; Octoil S; Decanedioic acid, bis(2-ethylhexyl) ester; Reolube DOS; Staflex DOS; diethylhexyl sebacate; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Uniflex dos; 2-Ethylhexyl sebacate; Edenol 888; Plexol 201J; Sansocizer DOS; Ergoplast SDO; Reomol DDS; Edenor DEHS; Sebacic acid, bis(2-ethylhexyl) ester; Sebacic acid bis(2-ethylhexyl) ester; Di(2-ethylhexyl)sebacate; Di-2-ethylhexyl sebacate; PX 438; 1-Hexanol, 2-ethyl-, sebacate; UNII-U9LS47Q72Q; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); NSC 68878; Bis(ethylhexyl) sebacate, MFCD00009497; Decanedioic acid, 1,10-bis(2-ethylhexyl) ester; DOS; Sebacic acid, bis(2-ethylhexyl)ester; Bis-(2-ethylhexyl)ester kyseliny sebakove; U9LS47Q72Q; decanedioic acid bis(2-ethylhexyl) ester; Bis(2-ethylhexyl) sebacate, 97%; Dioctyl sebacate (VAN); USAF KE-2; Di-2-ethylhexyl isosebacate; CCRIS 6191; HSDB 2898; EINECS 204-558-8; Sebacic acid, di-2-ethylhexyl diester; Isosebacic acid, di-2-ethylhexyl ester; BRN 1806504; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Bis(2-ethylhexyl)decanedioate, AI3-09124; Ergoplast SNO; Plasthall DOS; Bis-(2-ethylhexyl)ester kyseliny sebakove [Czech]; Sebacic acid di(2-ethylhexyl) ester; BEHS; 1-Hexanol, sebacate; Plexol 201; ACMC-209ali; bis(2_ethylhexyl)sebacate; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); DSSTox_CID_5055; EC 204-558-8; DSSTox_RID_77644; DSSTox_GSID_25055, SCHEMBL37169, 4-02-00-02083 (Beilstein Handbook Reference); KSC909K1N; Sebacic acid bis(2-ethylhexyl); CHEMBL3187356; DTXSID7025055; CTK8A9516; NSC68878; Tox21_303439; ANW-18004; NSC-68878; AKOS015903925; Bis(2-ethylhexyl) ester, sebacic acid; MCULE-4334197745; decanedioic acid bis(2_ethylhexyl) ester; NCGC00257416-01; 29590-28-1; CAS-122-62-3; SC-47142; Decanedioic acid, di-(2-ethylhexyl) ester; Bis(2-ethylhexyl) ester, decanedionic acid; DB-041675; FT-0631704; S0025; WLN: 4Y2 & 1OV8VO1Y4 & 2; SEBACIC ACID BIS (2_ETHYLHEXYL) ESTER; Sebacic acid, bis(2-ethylhexyl) ester (8CI); Bis(2-ethylhexyl) sebacate, >=97.0% (GC); Bis(2-ethylhexyl) sebacate, technical grade, 90%; J-004836; Q4387284; Bis(2-ethylhexyl) sebacate, Selectophore(TM), >=97.0%; di(2-ethylhexyl) sebacate, Sebacic acid di(2-ethylhexyl) ester, Bis(2-Ethylhexyl) decanedioate, Dioctyl Sebacate, 1-Hexanol, 2-ethyl-, sebacate, 2-Ethylhexyl sebacate, Bisoflex DOS, Decanedioic acid, bis(2-ethylhexyl)ester, Di(2-ethylhexyl) sebacate, Monoplex DOS, Octoil S, Octyl sebacate, Staflex DOS; bisoflex; bisoflex DOS; decane dioic acid bis(2-ethyl hexyl) ester; decanedioic acid bis(2-ethylhexyl) ester; decanedioic acid di(2-ethylhexyl) ester; decanedioic acid, bis(2-ethylhexyl) ester; di-2-ethylhexyl sebacate; di(2-ethyl hexyl) sebacate; di(2-ethylhexyl) sebacate; di(2-ethylhexyl)sebacate; di2-ethylhexyl decane-1,10-dioate; diethyl hexyl sebacate; diethylhexyl sebacate; dioctyl sebacate; dub green DOS; edenol 888; edenor dehs; ergoplast SDO; bis(2-ethyl hexyl) decane dioate; (±)-bis(2-ethyl hexyl) sebacate; 2-ethylhexyl sebacate; bis(2-ethylhexyl) decanedioate; (±)-bis(2-ethylhexyl) sebacate; bis(ethylhexyl) sebacate; bis(2-ethylhexyl) sebacate; hallstar DOS; monoplex DOS; octoil S; plexol; plexol 201; plexol 201J; ransocizer DOS; reolube DOS; reomol DDS; sansocizer DOS; sebacic acid bis(2-ethyl hexyl) ester; sebacic acid bis(2-ethylhexyl) ester; sebacic acid di(2-ethylhexyl) ester; sebacic acid, bis(2-ethylhexyl) ester; sebacic acid, bis(2-ethylhexyl) ester (8CI); sebacic acid, bis(2-ethylhexyl)ester; sebacic acid, di-2-ethylhexyl diester; staflex DOS; uniflex DOS; uniplex DOS; 219-411-3 [EINECS]; 2432-87-3 [RN]; CG4EO6A0O2; Decanedioic acid dioctyl ester; Decanedioic acid, dioctyl ester [ACD/Index Name]; Di-n-octyl Sebacate; dioctyl decanedioate, Dioctyl sebacate [ACD/IUPAC Name] [Wiki]; Dioctylsebacat [German] [ACD/IUPAC Name]; MFCD00059269; Octyl sebacate; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Sébacate de dioctyle [French] [ACD/IUPAC Name]; Sebacic acid, dioctyl ester; 14491-66-8 [RN]; 27214-90-0 [RN]; decadioic acid, dioctyl ester; Decanedioic acid, diisooctyl ester; Decanedioic acid,1,10-dioctyl ester; DEHS; Di-n-OctylSebacate; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); DOS; Monoplex DOS; Octoil S; Plexol 201; QA-7926; sebacic acid dioctyl ester; SEBACICACIDDI-N-OCTYLESTER; Staflex DOS; U niflex DOS; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS); UNII:CG4EO6A0O2; UNII-CG4EO6A0O2; Witamol 500; Dioctyl Sebacate (DOS); DİOKTİL SÜLFAT; dioktil sülfat; DIOCTYL SEBACATE (DOS)

DIOCTYL SEBACATE (DOS)

APPLICATION
Dioctyl Sebacate(DOS) is used as a plasticizer for PVC, nitrocelluloses, styrene resins, and synthetic rubbers where low temperature performance is required. DOS is also compliant with FDA CFR 21 for food contact materials. Dioctyl Sebacate can also be used in lubricants to allow more mobility at lower temperatures. DOS can be used as anti-frosting cable, artificial leather, outdoor cable, PVC linoleum, resins and synthetic rubbers. Dioctyl Sebacate provides a silky feel and spreads easily. Because of this, Dioctyl Sebacate finds use in the personal care industry and is found in deodorants and antiperspirants, makeup, skin conditioners, lotions, and sunscreens.

Dioctyl sebacate

Infobox references
Dioctyl sebacate (di(2-ethylhexyl) sebacate) is an organic compound which is the diester of sebacic acid and 2-ethylhexanol. It is an oily colorless liquid and is used as a plasticizer, including in the explosive C4.[1] It has also found use in Dot 5 brake fluid and ester based engine oils and additives. Furthermore, the substance is also commonly used as seed particle for Particle Image Velocimetry

In the coatings industry, soft PVC is mainly used to coat truck tarpaulins, marquees, floor coverings and as metal coatings. While dioctyl sebacate (di(2-ethylhexyl) sebacate, or DOS) is a widely used plasticizer, it has become more challenging for companies to acquire sebacic acid-based plasticizers like DOS due to increasing costs, along with the uncertainty and lack of stable supply of sebacic acid. EDENOL® DOZ is a new plasticizer able to replace DOS in developing most soft PVC coatings.

The Uncertainty of Sebacic Acid Supply
Sebacic acid, also known as decanedioic acid, is a useful building block for plasticizers and polymers. The most well-known polymer derived from sebacic acid is polyamide (PA 6.10). Sebacic acid is produced on an industrial scale mainly from castor oil, which is a biobased raw material. Therefore, products made from sebacic acid can be labeled as partially or fully biobased depending upon the other ingredients in the end-product formulation.

The production capacities of sebacic acid from castor oil are mainly located in China and India. In December 2016, the Chinese government ordered a shutdown of factories in northeast China, with the target to reduce the heavy air pollution in that region.1 As several plants producing sebacic acid were affected by this measure, this shutdown was followed by a series of force majeure declarations on sebacic acid. With the restrictions on air pollution becoming even stricter in the future, this situation most likely will occur again during the next Chinese winter season.

Impact on Dioctyl Sebacate Plasticizer
One of the products derived from sebacic acid that was heavily affected by the force majeure is the widely used plasticizer, DOS. DOS, an odorless and colorless liquid with low viscosity, is generated by reacting sebacic acid with 2-ethyl hexanol. DOS is food contact compliant according to FDA CFR 21. It has become an industry standard as a low-temperature plasticizer for PVC coatings due to its low volatility and good weathering properties.

However, because of these supply challenges, the PVC industry is in need of a technically equivalent plasticizer to DOS from a secure supply chain. The alternative should also be FDA food contact compliant and at least partially biobased to meet market needs.

Readily Available Azelaic Acid Alternative
Azelaic acid, also known as nonanedioic acid, is a viable substitute for sebacic acid as it differs only slightly in chemical structure. Emery Oleochemicals was the pioneer in the commercial development of azelaic acid over 60 years ago.2 Emery’s integrated manufacturing processes and readily available feedstock of azelaic acid through its proprietary ozonolysis process ensures a secure supply to the market.

Starting from natural oils and fats, the company produces oleic acid, among other oleochemicals. This oleic acid is then fed into Emery’s proprietary ozonolysis process, which cleaves the oleic acid with ozone based on natural oxygen. The cleaved products are azelaic acid and pelargonic acid, which are then further purified.

A New Alternative
A new alternative to DOS, EDENOL DOZ is di(2-ethyl hexyl), or dioctyl azelate, which provides the following benefits:

food contact compliance according to FDA CFR 21;
partially biobased material, with azelaic acid derived from natural sources;
same, or very similar, application characteristics in PVC compared to DOS, which is outlined later in this article; and
security of supply: the production process is back-integrated, beginning with conversion of natural fats and oils feedstock into oleic acid, production of azelaic acid by ozonolysis, and finally, synthesis of the ester EDENOL DOZ.

Comparison of EDENOL DOZ and DOS
As azelaic acid is a close homologue of sebacic acid, the respective esters are very similar in their product properties. As shown in Table 1, viscosity and specific gravity are the same. Thus, when switching from DOS to EDENOL DOZ, little to nothing needs to be changed in the dosing system.

Since the chemical structure and physicochemical properties of EDENOL DOZ and DOS are very similar, the behavior of both plasticizers in a PVC formulation was compared. A basic PVC formulation was used: a CaZn-stabilized PVC with epoxidized soy bean oil as co-stabilizer and the plasticizers, EDENOL DOZ or DOS, at two respective dosage levels of 40 or 70 phr (Table 2).

Comparing EDENOL DOZ and DOS, one can recognize the deviations are quite small and often within, or close to, the tolerances of the respective measurement. The Shore hardness tends to be slightly lower with EDENOL DOZ compared to DOS; therefore, the plasticizer dosage in this formulation could have been reduced when switching from DOS to EDENOL DOZ. With the tensile strength at 40 phr dosage being the same for both plasticizers, the difference at the higher dosage is minimal. Breaking tension, elongation at break and the cold flex temperature do not show any significant differences. The extraction resistance to iso-octane shows a small advantage for EDENOL DOZ within the accuracy of the measurement. Although the differences in behavior depend upon the full formulation used, EDENOL DOZ is certainly the closest alternative to DOS that is available in the market.

Conclusion
EDENOL DOZ provides similar properties to DOS in substance as well as incorporated in PVC. Both plasticizers provide food contact compliance according to FDA CFR 21 and both are partially biobased materials. However, while DOS is dependent upon the supply chain of castor oil and sebacic acid, the new plasticizer is based on azelaic acid, which is derived from a reliable and proven process of ozonolysis of oleic acid. Oleic acid is sourced from numerous natural fats and oils, so EDENOL DOZ provides the highest level of safety of supply for the PVC industry, and therefore, it represents a viable and sustainable replacement for DOS. 

Dioctyl Sebacate (DOS)

Dioctyl Sebacate(DOS). Acts as a plasticizer. It is a colorless or light yellow oily liquid with a special smell. Possesses low volatility, electrical insulation and high plasticizing rate. It is not only cold-resistant but also light-proof and heat-resistant. It dissolves in hydrocarbons, alcohols, ester, chlorocarbons, ether, benzene and other organic solvents. This product is mainly used in polyvinyl chloride, chloroethylene copolymer, nitrocellulose, ethyl cellulose and synthetic rubber, etc. It is specially suitable material for making cold resistant cables, leatherette, thin film, sheet materials and so on. Its application is often in combination with acetate o-phthalate plasticizer. Can also be used in producing many kinds of synthetic rubbers, which is applied in low temperature and it has no effect on vulcanization of rubbers.
Product Type    Plasticizers > Sebacates
Chemical Composition    Dioctyl Sebacate
CAS Number    122-62-3

Dioctyl sebacate, or di(2-ethylhexyl) sebacate, is an organic compound which is the diester of sebacic acid and 2-ethylhexanol. It is an oily colorless liquid.
Dioctyl Sebacate is a plasticizer for PVC, and its copolymers, nitrocelluloses, styrene resins and synthetic rubbers where low temperature  performance is required. The end applications include anti-frosting cable and PVC linoleum.
Bis(2-ethylhexyl) sebacate is an ester. Esters react with acids to liberate heat along with alcohols and acids.
Dioctyl sebacate is an excellent freeze-resisting plasticizer used in PVC, chlorethlene polymer, cellulose nitrate ,ethyl cellulose and synthetic rubber, with high plasticizing efficiency, low volatility, good cold-resisting property, light-resisting and electric insulating property.
Dioctyl sebacate is used for PVC and its copolymers modification. It is widely used for manufacturing of frost-resisting cable plasticator, leatherette for aircraft and motor transport, PVC linoleum etc. and it is also a fine cold-restart plasticizer.
Di(2-ethylhexyl)phthalate, commonly referred to as DEHP, is predominantly used as a plasticizer in the production of flexible polyvinyl chloride
(PVC) products. At least 95% of DEHP produced is used as a plasticizer for PVC.
The use of DEHP in domestically produced baby teethers and rattles has been discontinued, and DEHP is also no longer used as a plasticizer in plastic food wrap products.
General
Di-2-ethyl hexyl sebacate
About Dioctyl sebacate
Patent

Aluminum sheet coated with a lubricant comprising dioctyl sebacate and petrolatum
Process for the preparation of a composite mat
Preparation of fluorescent thermal transfer sheet by monomer polymerization method
Process for the preparation of rubber mixtures containing water repellent oxide or silicate fillers, and the use thereof for the manufacture of tires
Transdermal antiandrogenic compositions and modulated process
Material Safety Data Sheet

Di-2-ethylhexyl Sebacate
Dioctyl sebacate
Material safety data sheet on Dioctyl sebacate
Safety data for dioctyl sebacate

Applications
Some air oxidation products of di-2-ethylhexyl sebacate
Determination of Steam-Volatile Organic Acids in Fermentation Media by Gas-Liquid Chromatography
Volatility and solvent extractability of plasticizers used in PVC 
Public Health Goal for Di(2- Ethylhexyl)Phthalate (DEHP) in Drinking Water
Products

Di-2-ethylhexyl sebacate(DOS)
Dioctyl sebacate
Dioctyl sebacate(DOS)
Bis(2-ethylhexyl) sebacate 
Dioctyl sebacate(DOS)
Dioctyl Sebacate(DOS)
DI(2-ethylhexyl) Sebacate
Reports

National industrial chemicals notification and assessment scheme
Phthalates, Adipates, Citrate and some of the other plasticizers detected in japanese retail foods: a survey
Toxicological profile for di(2-ethyl hexyl) phthalate
Hazards

Accurate Energetic Systems, LLC
Bis(2-ethylhexyl) sebacate
Di(2-ethylhexyl) Sebacate
Di(2-ethyl hexyl) Sebacate
Suppliers

Dioctyl sebacate suppliers
Dioctyl sebacate exporters

Dioctyl Sebacate (DOS) is an ester of sebacic acid that is useful in lithium hydroxystearate complex grease applications as well as use in a base stock for engine oils. It has functional value in low temperature applications and can be used to replace sodium nitrites in aluminum greases. Applications include aircraft, trucks, automobiles, and equipment in cold temperature conditions.

APPLICATION
Dioctyl Sebacate(DOS) is used as a plasticizer for PVC, nitrocelluloses, styrene resins, and synthetic rubbers where low temperature performance is required. DOS is also compliant with FDA CFR 21 for food contact materials. Dioctyl Sebacate can also be used in lubricants to allow more mobility at lower temperatures. DOS can be used as anti-frosting cable, artificial leather, outdoor cable, PVC linoleum, resins and synthetic rubbers. Dioctyl Sebacate provides a silky feel and spreads easily. Because of this, Dioctyl Sebacate finds use in the personal care industry and is found in deodorants and antiperspirants, makeup, skin conditioners, lotions, and sunscreens.

Dioctyl sebacate

Infobox references
Dioctyl sebacate (di(2-ethylhexyl) sebacate) is an organic compound which is the diester of sebacic acid and 2-ethylhexanol. It is an oily colorless liquid and is used as a plasticizer, including in the explosive C4.[1] It has also found use in Dot 5 brake fluid and ester based engine oils and additives. Furthermore, the substance is also commonly used as seed particle for Particle Image Velocimetry

In the coatings industry, soft PVC is mainly used to coat truck tarpaulins, marquees, floor coverings and as metal coatings. While dioctyl sebacate (di(2-ethylhexyl) sebacate, or DOS) is a widely used plasticizer, it has become more challenging for companies to acquire sebacic acid-based plasticizers like DOS due to increasing costs, along with the uncertainty and lack of stable supply of sebacic acid. EDENOL® DOZ is a new plasticizer able to replace DOS in developing most soft PVC coatings.

The Uncertainty of Sebacic Acid Supply
Sebacic acid, also known as decanedioic acid, is a useful building block for plasticizers and polymers. The most well-known polymer derived from sebacic acid is polyamide (PA 6.10). Sebacic acid is produced on an industrial scale mainly from castor oil, which is a biobased raw material. Therefore, products made from sebacic acid can be labeled as partially or fully biobased depending upon the other ingredients in the end-product formulation.

The production capacities of sebacic acid from castor oil are mainly located in China and India. In December 2016, the Chinese government ordered a shutdown of factories in northeast China, with the target to reduce the heavy air pollution in that region.1 As several plants producing sebacic acid were affected by this measure, this shutdown was followed by a series of force majeure declarations on sebacic acid. With the restrictions on air pollution becoming even stricter in the future, this situation most likely will occur again during the next Chinese winter season.

Impact on Dioctyl Sebacate Plasticizer
One of the products derived from sebacic acid that was heavily affected by the force majeure is the widely used plasticizer, DOS. DOS, an odorless and colorless liquid with low viscosity, is generated by reacting sebacic acid with 2-ethyl hexanol. DOS is food contact compliant according to FDA CFR 21. It has become an industry standard as a low-temperature plasticizer for PVC coatings due to its low volatility and good weathering properties.

However, because of these supply challenges, the PVC industry is in need of a technically equivalent plasticizer to DOS from a secure supply chain. The alternative should also be FDA food contact compliant and at least partially biobased to meet market needs.

Readily Available Azelaic Acid Alternative
Azelaic acid, also known as nonanedioic acid, is a viable substitute for sebacic acid as it differs only slightly in chemical structure. Emery Oleochemicals was the pioneer in the commercial development of azelaic acid over 60 years ago.2 Emery’s integrated manufacturing processes and readily available feedstock of azelaic acid through its proprietary ozonolysis process ensures a secure supply to the market.

Starting from natural oils and fats, the company produces oleic acid, among other oleochemicals. This oleic acid is then fed into Emery’s proprietary ozonolysis process, which cleaves the oleic acid with ozone based on natural oxygen. The cleaved products are azelaic acid and pelargonic acid, which are then further purified.

A New Alternative
A new alternative to DOS, EDENOL DOZ is di(2-ethyl hexyl), or dioctyl azelate, which provides the following benefits:

food contact compliance according to FDA CFR 21;
partially biobased material, with azelaic acid derived from natural sources;
same, or very similar, application characteristics in PVC compared to DOS, which is outlined later in this article; and
security of supply: the production process is back-integrated, beginning with conversion of natural fats and oils feedstock into oleic acid, production of azelaic acid by ozonolysis, and finally, synthesis of the ester EDENOL DOZ.

Comparison of EDENOL DOZ and DOS
As azelaic acid is a close homologue of sebacic acid, the respective esters are very similar in their product properties. As shown in Table 1, viscosity and specific gravity are the same. Thus, when switching from DOS to EDENOL DOZ, little to nothing needs to be changed in the dosing system.

Since the chemical structure and physicochemical properties of EDENOL DOZ and DOS are very similar, the behavior of both plasticizers in a PVC formulation was compared. A basic PVC formulation was used: a CaZn-stabilized PVC with epoxidized soy bean oil as co-stabilizer and the plasticizers, EDENOL DOZ or DOS, at two respective dosage levels of 40 or 70 phr (Table 2).

Comparing EDENOL DOZ and DOS, one can recognize the deviations are quite small and often within, or close to, the tolerances of the respective measurement. The Shore hardness tends to be slightly lower with EDENOL DOZ compared to DOS; therefore, the plasticizer dosage in this formulation could have been reduced when switching from DOS to EDENOL DOZ. With the tensile strength at 40 phr dosage being the same for both plasticizers, the difference at the higher dosage is minimal. Breaking tension, elongation at break and the cold flex temperature do not show any significant differences. The extraction resistance to iso-octane shows a small advantage for EDENOL DOZ within the accuracy of the measurement. Although the differences in behavior depend upon the full formulation used, EDENOL DOZ is certainly the closest alternative to DOS that is available in the market.

Conclusion
EDENOL DOZ provides similar properties to DOS in substance as well as incorporated in PVC. Both plasticizers provide food contact compliance according to FDA CFR 21 and both are partially biobased materials. However, while DOS is dependent upon the supply chain of castor oil and sebacic acid, the new plasticizer is based on azelaic acid, which is derived from a reliable and proven process of ozonolysis of oleic acid. Oleic acid is sourced from numerous natural fats and oils, so EDENOL DOZ provides the highest level of safety of supply for the PVC industry, and therefore, it represents a viable and sustainable replacement for DOS. 

Dioctyl Sebacate (DOS)

Dioctyl Sebacate(DOS). Acts as a plasticizer. It is a colorless or light yellow oily liquid with a special smell. Possesses low volatility, electrical insulation and high plasticizing rate. It is not only cold-resistant but also light-proof and heat-resistant. It dissolves in hydrocarbons, alcohols, ester, chlorocarbons, ether, benzene and other organic solvents. This product is mainly used in polyvinyl chloride, chloroethylene copolymer, nitrocellulose, ethyl cellulose and synthetic rubber, etc. It is specially suitable material for making cold resistant cables, leatherette, thin film, sheet materials and so on. Its application is often in combination with acetate o-phthalate plasticizer. Can also be used in producing many kinds of synthetic rubbers, which is applied in low temperature and it has no effect on vulcanization of rubbers.
Product Type    Plasticizers > Sebacates
Chemical Composition    Dioctyl Sebacate
CAS Number    122-62-3

Dioctyl sebacate, or di(2-ethylhexyl) sebacate, is an organic compound which is the diester of sebacic acid and 2-ethylhexanol. It is an oily colorless liquid.
Dioctyl Sebacate is a plasticizer for PVC, and its copolymers, nitrocelluloses, styrene resins and synthetic rubbers where low temperature  performance is required. The end applications include anti-frosting cable and PVC linoleum.
Bis(2-ethylhexyl) sebacate is an ester. Esters react with acids to liberate heat along with alcohols and acids.
Dioctyl sebacate is an excellent freeze-resisting plasticizer used in PVC, chlorethlene polymer, cellulose nitrate ,ethyl cellulose and synthetic rubber, with high plasticizing efficiency, low volatility, good cold-resisting property, light-resisting and electric insulating property.
Dioctyl sebacate is used for PVC and its copolymers modification. It is widely used for manufacturing of frost-resisting cable plasticator, leatherette for aircraft and motor transport, PVC linoleum etc. and it is also a fine cold-restart plasticizer.
Di(2-ethylhexyl)phthalate, commonly referred to as DEHP, is predominantly used as a plasticizer in the production of flexible polyvinyl chloride
(PVC) products. At least 95% of DEHP produced is used as a plasticizer for PVC.
The use of DEHP in domestically produced baby teethers and rattles has been discontinued, and DEHP is also no longer used as a plasticizer in plastic food wrap products.
General
Di-2-ethyl hexyl sebacate
About Dioctyl sebacate
Patent

Aluminum sheet coated with a lubricant comprising dioctyl sebacate and petrolatum
Process for the preparation of a composite mat
Preparation of fluorescent thermal transfer sheet by monomer polymerization method
Process for the preparation of rubber mixtures containing water repellent oxide or silicate fillers, and the use thereof for the manufacture of tires
Transdermal antiandrogenic compositions and modulated process
Material Safety Data Sheet

Di-2-ethylhexyl Sebacate
Dioctyl sebacate
Material safety data sheet on Dioctyl sebacate
Safety data for dioctyl sebacate

Applications
Some air oxidation products of di-2-ethylhexyl sebacate
Determination of Steam-Volatile Organic Acids in Fermentation Media by Gas-Liquid Chromatography
Volatility and solvent extractability of plasticizers used in PVC 
Public Health Goal for Di(2- Ethylhexyl)Phthalate (DEHP) in Drinking Water
Products

Di-2-ethylhexyl sebacate(DOS)
Dioctyl sebacate
Dioctyl sebacate(DOS)
Bis(2-ethylhexyl) sebacate 
Dioctyl sebacate(DOS)
Dioctyl Sebacate(DOS)
DI(2-ethylhexyl) Sebacate
Reports

National industrial chemicals notification and assessment scheme
Phthalates, Adipates, Citrate and some of the other plasticizers detected in japanese retail foods: a survey
Toxicological profile for di(2-ethyl hexyl) phthalate
Hazards

Accurate Energetic Systems, LLC
Bis(2-ethylhexyl) sebacate
Di(2-ethylhexyl) Sebacate
Di(2-ethyl hexyl) Sebacate
Suppliers

Dioctyl sebacate suppliers
Dioctyl sebacate exporters

Dioctyl Sebacate (DOS) is an ester of sebacic acid that is useful in lithium hydroxystearate complex grease applications as well as use in a base stock for engine oils. It has functional value in low temperature applications and can be used to replace sodium nitrites in aluminum greases. Applications include aircraft, trucks, automobiles, and equipment in cold temperature conditions.

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