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Disodium laureth sulfosuccinate acts as a de-greasing, emulsifier, and a foaming agent which is used in many shampoos and other cleaning products. It is considered as a gentle cleansing ingredient for hair & skin.
CAS No.: 13192-12-6
EC No.: 236-149-5
Synonyms:
DISODIUM LAURETH SULFOSUCCINATE; Sodium Lauryl Sulfoacetate; Disodium Laureth Sulfosuccinate; Disodium 4-dodecyl 2-sulphonatosuccinate; DLSS; DLS; Disodium Lauryl Sulfosuccinate Powder; Plantapon SUS; Disodium C12-18 alkyl sulfosuccinate; LAURETH SULFOSUCCINATE DISODIUM SALT; disodium [(dodecyloxy)sulphonyl]succinate; LAURYL ETHER SULFOSUCCINATE DISODIUM SALT; DODECYL ETHER SULFOSUCCINATE DISODIUM SALT;Dodecyloxysulfonylsuccinic acid disodium salt; 2-(Laurylsulfo)succinic acid 1,4-disodium salt; [(dodecyloxy)sulfonyl]-butanedioicacidisodiumsalt; Butanedioic acid; (dodecyloxy)sulfonyl-; disodium salt;Butanedioic acid; sulfo-, 4-2-2-2-(dodecyloxy)ethoxyethoxyethyl ester; disodium salt; dodecoxysulfonylbutanedioate; Butanedioic acid; ((dodecyloxy)sulfonyl)- disodium salt; Disodium ((dodecyloxy)sulphonyl)succinate;Disodium laureth sulfosuccinate(MESD); Succinic acid; sulfo-monododecyl; DISODIUM LAURYL SULFOSUCCINATE; DODECYL ETHER SULFOSUCCINATE DISODIUM SALT;LAURETH SULFOSUCCINATE DISODIUM SALT; LAURYL ETHER SULFOSUCCINATE DISODIUM SALT; [(dodecyloxy)sulfonyl]-butanedioicacidisodiumsalt; disodium [(dodecyloxy)sulphonyl]succinate; Butanedioic acid; (dodecyloxy)sulfonyl- disodium salt; Butanedioic acid; sulfo-, 4-2-2-2-(dodecyloxy)ethoxyethoxyethyl ester; disodium salt; sodium dodecyl sulphate (Sodium lauryl sulfate (SLS) ); Sodium dodecyl sulfate; 151-21-3; SODIUM LAURYL SULFATE; Sodium lauryl sulphate; Sodium dodecylsulfate; Neutrazyme; Irium; Dodecyl sodium sulfate; Sodium dodecyl sulphate; Anticerumen; Gardinol; Duponal; Duponol; Dreft; Aquarex methyl; Duponol methyl; Solsol needles; Stepanol methyl; Duponol waqa; Stepanol wac; Stepanol waq; Richonol af; Duponol qx; Perlandrol L; Perlankrol L; Sipex sb; Sipex sd; Standapol wa-ac; Stepanol me dry; Dodecyl sulfate sodium salt; Duponol Me; Richonol A; Richonol C; Sintapon L; Duponol C; Finasol osr2; Maprofix LK; Standapol WAQ; Stepanol ME; Stepanol WA; Akyposal Sodium lauryl sulfate (SLS) ; Carsonol Sodium lauryl sulfate (SLS) ; Incronol Sodium lauryl sulfate (SLS) ; Maprobix NEU; Maprofix NEU; Maprofix WAC; Aquarex ME; Duponol QC; Duponol WA; Duponol WA dry; Melanol CL; Dupanol WAQ; Duponal WAQE; Duponol WAQ; Duponol WAQE; Duponol WAQM; Empicol LPZ; Hexamol Sodium lauryl sulfate (SLS) ; Lanette Wax-S; Natrium laurylsulfuricum; Sterling wa paste; Conco sulfate WA; Conco sulfate WN; Dodecyl sulfate, sodium salt; Natriumlaurylsulfat; Nikkol Sodium lauryl sulfate (SLS) ; Orvus WA Paste; Sipex OP; Sipex SP; Sipex UB; Sipon LS; Sipon PD; Sipon WD; Detergent 66; Montopol La Paste; Sipon LSB; Maprofix WAC-LA; Sodium n-dodecyl sulfate; Sterling WAQ-CH; Cycloryl 21; Cycloryl 31; Stepanol WA Paste; Conco Sulfate WAG; Conco Sulfate WAN; Conco Sulfate WAS; Quolac EX-UB; Avirol 118 conc; Odoripon Al 95; Cycloryl 580; Cycloryl 585N; Lauryl sodium sulfate; Maprofix 563; Sinnopon LS 95; Stepanol T 28; Steinapol NLS 90; Sulfuric acid monododecyl ester sodium salt; Empicol LS 30; Empicol LX 28; Lauryl sodium sulfate; Melanol CL 30; NALS; Rewopol NLS 30; Standapol waq special; Standapol was 100; Jordanol SL-300; Sinnopon LS 100; Stepanol WA-100; Carsonol Sodium lauryl sulfate (SLS) Special; Finasol osr(sub 2); Standapol 112 conc; Stepanol ME Dry AW; Avirol 101; Dodecyl sulfate sodium; Perklankrol ESD 60; Caswell No. 779; Emersal 6400; Monagen Y 100; Monogen Y 100; Carsonol Sodium lauryl sulfate (SLS) Paste B; Stepanol methyl dry aw; Berol 452; Emal 10; EMAL O; Laurylsiran sodny; Sipon LS 100; n-Dodecyl sulfate sodium; Sodium monolauryl sulfate; Monododecyl sodium sulfate; Sodium monododecyl sulfate; Sodiumlauryl ether sulfate; Lauryl sulfate sodium salt; Conco sulfate WA-1200; Conco sulfate WA-1245; Laurylsiran sodny [Czech]; Dehydag sulfate GL emulsion; Lauryl sulfate, sodium salt; Dehydrag sulfate gl emulsion; Dehydag sulphate GL emulsion; MFCD00036175; Rhodapon UB; Product no. 75; Sodium lauryl sulfate ether; Sodium lauryl sulfate 30%; Product no. 161; Emulsifier no. 104; Sodium Laurylsulfate; Sodium lauryl sulfate (SLS) Running Buffer; CCRIS 6272; Lauryl sulfate sodium; Sodium lauryl sulfate (SLS) ; UNII-368GB5141J; HSDB 1315; Texapon K 1296; P and G Emulsifier 104; NCI-C50191; Sodium lauryl sulfate, dental grade; Dodecyl alcohol, hydrogen sulfate, sodium salt; EINECS 205-788-1; EPA Pesticide Chemical Code 079011; NSC 402488; CP 75424; AI3-00356; CHEBI:8984; Laurylsulfuric Acid Sodium Salt; Dodecylsulfuric Acid Sodium Salt; Sulfuric acid, monododecyl ester, sodium salt; Sulfuric acid monododecyl ester sodium salt (1:1); Sulfotex wala; Sulfotex wa; Texapon zhc; 368GB5141J; Trepenol WA; NCGC00091020-03; Texapon V hc; Sulfopon wa 1; Sulfopon WA2; Sulfopon WA3; Swascol 3L; Swascol 4L; Texapon DL Conc.; Texapon K12; DSSTox_CID_6031; Sulfetal L 95; Ultra sulfate sl-1; Tarapon K 12; Texapon K 12; WAQE; Sterling waq-cosmetic; Texapon V HC Powder; Sulfopon WA1 Special; Texapon K1296; Texapon L 100; DSSTox_RID_77989; DSSTox_GSID_26031; Perlankrol E.S.D. 60; dodecyl hydroxysulfonate, sodium salt; Texapon Z High Conc. Needles; sodiumdodecylsulfate; CAS-151-21-3; SODIUM DODECYL SULFATE, ULTRA PURE; Dodecyl sulfate, sodium salt, 85%, pure; Dodecyl sulfate, sodium salt, 99%, for biochemistry; Sulfolyser; Dermacide; Empicol; Sandet ona; Sipon ub; Supralate C; Syntapon L; Witcolate A; Emulsogen LS; Lanette wax s; Emal os; Fongrapol LSS; Rhodapon SB; Rhodapon SM; Steinapol NLS; Sulfochem Sodium lauryl sulfate (SLS) ; Akyposal NLS; Monogen LH; Rhodapon LCP; Rhodapon LSB; Stepanal WAC; Empicol LXV; Empimin Sodium lauryl sulfate (SLS) ; Genapol LSS; Rolpon LS; Sodium lauryl sulfate ; Carsonol Sodium lauryl sulfate (SLS) -s; Dodecyl sulfate, sodium salt, 99+%, for molecular biology, DNAse, RNAse and Protease free; Dodecyl sulfate, sodium salt, pure, granular, spec. acc. the requirements of Ph.Eur.; Equex S; Surfactant K12; Equex SP; Orvus WA; Swascol 1P; Emal 2F Needle; Empicol LZ/D; Nissan persoft SP; Stepanol WA extra; Cycloryl 21LS; Dehydag sulfate GL; Polystep B 3; Polystep B 5; Rosulfan L 1; sodiumlauryl sulfate; Standapol WAQ-LC; Sulfopon WA 2; Sulfopon WA 3; Sodium coco-sulfate; Sodium laurilsulfate; Sodium Lauryl Sulfate; Emal 10 Needle; Emal 10 Powder; Empicol LX 2; Finasol OSR 2; Stepanol WA special; Sulfopon T 30; Needle 10; Alscoap LN 40A; Alscoap LN 90; Alscoap MP 90N; Alscoap SP 40; Alscoap-LN 90P; Calfoam Sodium lauryl sulfate (SLS) 30; Emal 2F; Empicol BSD 70; Empicol LX 28R; Empicol LX 42; Empicol LY 28S; NADDS; Rewopol NLS 28; Sinolin 90TK-N; sodium dodecylsulphate; Stanfax 234; Texapon K 12G; Sodium dodecanesulfate; Stepanol WA 100; Pionin A 21; Ufarol AM 30; Ufarol TCL 92; Calfoam ES 303; Empicol 0303VA; Monogen Y 500; Sintrex L 100; Sodium dedecyl sulfate; Surfax 220; Adeka Hope LS 35; Adeka Hope LS 90; Empicol 0303; K 12 (surfactant); Sipon LCS 98; Sodium-dodecyl-S-Sodium lauryl sulfate (SLS) ; Gardinol type detergent; IPC-Sodium lauryl sulfate (SLS) ; Silipon RN 6031; Sorpol 5029O; Sorpol 8070; Texapon K 1298; Bio-Soft SDBS 60; Stepanol ME DRY Sodium lauryl sulfate (SLS) ; Empicol LXSV 938U; Sulfopon WA 1 Special; ACMC-1BXOT; Avirol SL 2010; Rhodapon SB 8208S; Sunnol LM 1130; Emal 2F30; Nissan Sintrex L 100; sodium n-dodecyl sulphate; Sodium Lauryl Sulfate NF; potassium @dodecyl sulfate; lauryl sulphate sodium salt; MP SILICA RP 18; EC 205-788-1; AC1MQ93Y; dodecyl sulphate sodium salt; SCHEMBL1102; C12H25NaO4S; sodium dodecyl sulfate (Sodium lauryl sulfate (SLS) ); KSC174S7B; n-Dodecyl sulfate sodium salt; ARONIS27060; CHEMBL23393; Sodium dodecyl sulfate, 99%; sodium dodecyl sulphate (Sodium lauryl sulfate (SLS) ); Sodium dodecyl sulphate solution; DTXSID1026031; CTK0H4970; dodecyl sulfuric acid sodium salt; KS-00000VTL; DBMJMQXJHONAFJ-UHFFFAOYSA-M; Dodecyl sulphuric acid sodium salt; Sodium lauryl sulfate (JP17/NF); CS-B1770; Tox21_111059; Tox21_201614; Tox21_300149; ANW-21329; LS-880; SBB060993; AKOS015897278; AKOS025147308; Tox21_111059_1; DB00815; Dodecyl sulfuric acid ester sodium salt; NE10918
DISODIUM LAURETH SULFOSUCCINATE
Disodium laureth sulfosuccinate acts as a de-greasing, emulsifier, and a foaming agent which is used in many shampoos and other cleaning products. It is considered as a gentle cleansing ingredient for hair & skin.
Disodium laureth sulfosuccinate is classified as :
Cleansing
Foaming
Foam boosting
Hydrotrope
Surfactant
What Is Disodium laureth sulfosuccinate?
Disodium laureth sulfosuccinate is a surfactant. It is a disodium salt of ethoxylated lauryl alcohol bound to sulfosuccinic acid. Disodium laureth sulfosuccinate is primarily used in cleansing products, including bubble baths, bath soaps and detergents, shampoos and shaving cream.
Why is it used in cosmetics and personal care products?
In cosmetics and personal care products, Disodium laureth sulfosuccinate functions as a surfactant
cleansing agent, a surfactant
foam booster or a surfactant
hydrotrope.
Scientific Facts of Disodium laureth sulfosuccinate:
Disodium laureth sulfosuccinate is an anionic surfactant. This means that this ingredient has a negative charge. The negative charge is associated with the sulfosuccinate portion of the compound. Surfactants function by reducing the surface tension of water which makes it easier to wash dirt from the skin and hair.
DLSS - Disodium laureth sulfosuccinate is an anionic surfactant in White Powder form, also known as Plantapon SUS. Disodium laureth sulfosuccinate is considerably milder than Sodium Laureth Sulphate and it has excellent foaming and degreasing properties when used in a range of Bath products.
Disodium laureth sulfosuccinate is a gentle surfactant agent that cleanses skin and hair.
Description of Disodium laureth sulfosuccinate
All surfactants are partly water-soluble and partly oil-soluble, allowing oil and water-based ingredients to blend well. This means it will trap oil-based dirt from hair and skin and allow it to be easily rinsed away.
Disodium laureth sulfosuccinate is often used as a milder alternative to sulfates, although one doesn't systematically replace the other as they are not the same material and will not behave in the same way with other ingredients.
Disodium laureth sulfosuccinate is a sulfate-free anionic surfactant and ECOCERT approved. It is an excellent Foaming agent which produces a creamy rich lather in your products. Disodium laureth sulfosuccinate is considerably milder than SLS whilst still producing plenty of foam. Disodium laureth sulfosuccinate can be used in Shampoos, Bubble Bath products, Bath Bombs, Liquid Soap bases, Soap Bars and Body Wash Bases. Please be aware this is a very fine powder, so use in a well-ventilated area when decanting and manufacturing your products.
Description of Disodium laureth sulfosuccinate: Very mild anionic co-surfactant, highly water soluble in a wide pH range, pH: 6.5 - 7.5 (in 5% aqueous solution). Contains 32% active substances. Preservative benzoic acid. Clear yellow liquid, no or faint odor.
CAS of Disodium laureth sulfosuccinate: 39354-45-5
INCI Name: Disodium laureth sulfosuccinate
Benefits of Disodium laureth sulfosuccinate:
Very mild co-surfactant compatible with anionic, nonionic, amphoteric surfactants
Useful also as primary surfactant due to its good foaming and cleansing properties
Especially suitable for products for delicate skin and baby shampoos,
Has good emulsifying properties (useful as secondary o/w emulsifier)
Use of Disodium laureth sulfosuccinate: Can be added to formulas as is. Recommended use level 4 - 40% depending on desired foaming and cleansing effects. For external use only.
Applications of Disodium laureth sulfosuccinate: Body washes, shampoos, bubble baths, cleansing lotions, creams, hand soaps, baby products, hair conditioners, cream rinses.
Country of Origin: USA
Raw material source of Disodium laureth sulfosuccinate: Coconut oil and sulfosuccinic acid
Manufacture of Disodium laureth sulfosuccinate: Sulfosuccinate is produced by reacting coconut-oil derived ethoxylated lauryl alcohol with sulfosuccinic acid which is made from maleic anhydride followed by addition of sodium bisulfite.
Animal Testing of Disodium laureth sulfosuccinate: Not animal tested
Disodium laureth sulfosuccinate (sodium dodecyl sulphate) is a kind of anionic surfactant, dissolves in the water easily, compatibility with anion and non-ionic, good performances on emulsifying, foaming, osmosis, detergency and de-centrality. Disodium laureth sulfosuccinate Powder Disodium laureth sulfosuccinate Powder is a widely used surfactant often used as a foaming agent in many common products like Bath products, shampoos, foaming powders and mony industrial and commercial cleaners. SaveonCitric offers a highly Active, high quality Disodium laureth sulfosuccinate Powdered Disodium laureth sulfosuccinate. If you are formulating a product like a powdered or tablet cleanser, or blending liquid hard surface or carpet cleaners, try Disodium laureth sulfosuccinate Powder. Check the FIFRa list if you are formulating blends and looking for an accepted surfactant. Sodium dodecyl sulfate , synonymously, Disodium laureth sulfosuccinate , or sodium laurilsulfate, is a synthetic organic compound with the formula CH3(CH2)11SO4Na. It is an anionic surfactant used in many cleaning and hygiene products. The sodium salt is of an organosulfate class of organics. It consists of a 12-carbon tail attached to a sulfate group, that is, it is the sodium salt of dodecyl hydrogen sulfate, the ester of dodecyl alcohol and sulfuric acid. Its hydrocarbon tail combined with a polar "headgroup" give the compound amphiphilic properties and so make it useful as a detergent.[not verified in body] Also derived as a component of mixtures produced from inexpensive coconut and palm oils, Disodium laureth sulfosuccinate is a common component of many domestic cleaning, personal hygiene and cosmetic, pharmaceutical, and food products, as well as of industrial and commercial cleaning and product formulations. Disodium laureth sulfosuccinate is a widely used surfactant in cleaning products, cosmetic, and personal care products. Disodium laureth sulfosuccinate 's uses in these products have been thoroughly evaluated and determined to be safe for consumers and the environment. Disodium laureth sulfosuccinate , sodium laurilsulfate or sodium dodecyl sulfate (Disodium laureth sulfosuccinate or NaDS) (C12H25SO4Na) is an anionic surfactant used as an emulsifying cleaning agent in many cleaning and hygiene products. Disodium laureth sulfosuccinate is a highly effective surfactant and is used in any task requiring the removal of oily stains and residues. For example, it is found in higher concentrations with industrial products including engine degreasers, floor cleaners, and car wash soaps. It is used in lower concentrations with toothpastes, shampoos, and shaving foams. It is an important component in bubble bath formulations for its thickening effect and its ability to create a lather.
WHAT IS Disodium laureth sulfosuccinate ?
Disodium laureth sulfosuccinate , also known as Sodium dodecyl sulfate, is a widely used surfactant in cleaning products, cosmetics, and personal care products. The Disodium laureth sulfosuccinate formula is a highly effective anionic surfactant used to remove oily stains and residues. It is found in high concentrations in industrial products, including engine degreasers, floor cleaners, and car wash products, where workplace protections can be implemented to avoid unsafe exposures. Disodium laureth sulfosuccinate is also used in lower concentrations in household and personal care products such as cleaning products, toothpastes, shampoos, and shaving foams.
SAFETY
Disodium laureth sulfosuccinate has been thoroughly reviewed for its safety by a number of governments. For example:
Based on a thorough safety review, including consideration of chronic risks, the U.S. Environmental Protection Agency (EPA) has issued an exemption for
Disodium laureth sulfosuccinate from the requirement of tolerance for residues when used as a component of food contact sanitizing solutions applied to all food contact surfaces in public eating places, dairy-processing equipment, and food-processing equipment and utensils at a maximum level in the end-use concentration of 350 parts per million (ppm). The regulation eliminates the need to establish a maximum permissible level for residues of Disodium laureth sulfosuccinate. The Food and Drug Administration (FDA) includes Disodium laureth sulfosuccinate on its list of multipurpose additives allowed to be directly added to food. Disodium laureth sulfosuccinate and Ammonium Lauryl Sulfate are also approved indirect food additives. For example, both ingredients are permitted to be used as components of coatings. Disodium laureth sulfosuccinate and Ammonium Lauryl Sulfate may be used in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Directive of the European Union. The Organization of Economic Cooperation and Development, which is an organization of 30-plus developed countries, has reviewed the human and environmental hazards of a category of chemicals that includes Disodium laureth sulfosuccinate. No chronic human health hazards, including carcinogenicity, were identified. The hazard assessment for the category (alkyl sulphates, alkane sulphonates and alpha-olefin sulphonates category) is posted on the OECD website.
Disodium laureth sulfosuccinate has also been thoroughly reviewed for human safety by an industry funded, independent panel, which found: There is no evidence of harm from the use of Disodium laureth sulfosuccinate in cosmetic products, where there is intentional, direct contact with the skin. The ingredient was reviewed in 1983 and re-reviewed in 2005 by the Cosmetic Ingredient Review (CIR)1 Expert Panel and found to be safe for use in cosmetic and personal care products. Disodium laureth sulfosuccinate can cause skin irritation in some persons, which is one reason why it is important to follow the label instructions when using a cleaning product. A complete report on Disodium laureth sulfosuccinate is available from CIR.
Structure
Disodium laureth sulfosuccinate is in the family of organosulfate compounds,[2] and has the formula, CH3(CH2)11SO4Na. It consists of a 12-carbon tail attached to a sulfate group, that is, it is the sodium salt of a 12-carbon alcohol that has been esterified to sulfuric acid. An alternative description is that it is an alkyl group with a pendant, terminal sulfate group attached. As a result of its hydrocarbon tail, and its anionic "head group", it has amphiphilic properties that allow it to form micelles, and so act as a detergent.
Physicochemical properties
The critical micelle concentration (CMC) in pure water at 25 °C is 8.2 mM,[1] and the aggregation number at this concentration is usually considered to be about 62.[3] The micelle ionization fraction (α) is around 0.3 (or 30%).[4]
Production
Disodium laureth sulfosuccinate is synthesized by treating lauryl alcohol with sulfur trioxide gas, oleum, or chlorosulfuric acid to produce hydrogen lauryl sulfate.[5] The resulting product is then neutralized through the addition of sodium hydroxide or sodium carbonate.[citation needed] Lauryl alcohol can be used in pure form or may be derived from either coconut or palm kernel oil by hydrolysis (which liberates their fatty acids), followed by hydrogenation.[citation needed] When produced from these sources, commercial samples of these "Disodium laureth sulfosuccinate " products are actually not pure Disodium laureth sulfosuccinate , rather a mixture of various sodium alkyl sulfates with Disodium laureth sulfosuccinate being the main component.[6] For instance, Disodium laureth sulfosuccinate is a component, along with other chain-length amphiphiles, when produced from coconut oil, and is known as sodium coco sulfate (SCS).[7] Disodium laureth sulfosuccinate is available commercially in powder, pellet, and other forms (each differing in rates of dissolution), as well as in aqueous solutions of varying concentrations.
DESCRIPTION: Anionic surfactant. Vegetable origin. Solid (powder form). Disodium laureth sulfosuccinate, also called Sodium dodecyl sulfate, is a surfactant used in many cleaning and hygiene products such as toothpastes, shampoos, and bubble baths. (flammable solid)
Applications
Cleaning and hygiene
Disodium laureth sulfosuccinate is mainly used in detergents for laundry with many cleaning applications.It is a highly effective surfactant and is used in any task requiring the removal of oily stains and residues; for example, Disodium laureth sulfosuccinate is found in higher concentrations with industrial products including engine degreasers, floor cleaners, and car wash soaps.In lower concentrations, it is found in toothpastes, shampoos, shaving creams, and bubble bath formulations, for its ability to create a foam (lather), for its surfactant properties, and in part for its thickening effect.[10]
Food additive
Disodium laureth sulfosuccinate, appearing as its synonym Disodium laureth sulfosuccinate , is considered as a generally recognized as safe (GRAS) ingredient, for food use according to the guidelines published in 21 CFR 172.822. It is used as an emulsifying agent and whipping aid. Disodium laureth sulfosuccinate is reported to temporarily diminish perception of sweetness.
Laboratory applications
Principal applications
Disodium laureth sulfosuccinate, in science referred to as sodium dodecyl sulfate , is used in cleaning procedures, and is commonly used as a component for lysing cells during RNA extraction and/or DNA extraction, and for denaturing proteins in preparation for electrophoresis in the Disodium laureth sulfosuccinate -PAGE technique. In the case of the Disodium laureth sulfosuccinate -PAGE application, the compound works by disrupting non-covalent bonds in the proteins, and so denaturing them, i.e., causing the protein molecules to lose their native conformations and shapes.[citation needed] By binding to the proteins with high affinity and in high concentrations, the negatively charged detergent provides all proteins with a similar net negative charge and therefore a similar charge-to-mass ratio. In this way, the difference in mobility of the polypeptide chains in the gel can be attributed solely to their size as opposed to both their size and charge.[16] It is possible to make separation based on the size of the polypeptide chain to simplify the analysis of protein molecules, this can be achieved by denaturing proteins with the detergent Disodium laureth sulfosuccinate .The association of Disodium laureth sulfosuccinate molecules with protein molecules imparts an associated negative charge to the molecular aggregate formed;[citation needed] this negative charge is significantly greater than the original charge of that protein.[citation needed] The electrostatic repulsion that is created by Disodium laureth sulfosuccinate binding forces proteins into a rod-like shape, thereby eliminating differences in shape as a factor for electrophoretic separation in gels.[citation needed] Dodecyl sulfate molecule has two negative charges at the pH value used for electrophoresis, this will lead the net charge of coated polypeptide chains to be much more negative than uncoated chains.[17] The charge-to-mass ratio is essentially identical for different proteins because Disodium laureth sulfosuccinate coating dominates the charge.
Miscellaneous applications
Disodium laureth sulfosuccinate is used in an improved technique for preparing brain tissues for study by optical microscopy. The technique, which has been branded as CLARITY, was the work of Karl Deisseroth and coworkers at Stanford University, and involves infusion of the organ with an acrylamide solution to bind the macromolecules of the organ (proteins, nucleic acids, etc.), followed by thermal polymerization to form a "brain-hydrogel" (a mesh interspersed throughout the tissue to fix the macromolecules and other structures in space), and then by lipid removal using Disodium laureth sulfosuccinate to eliminate light scattering with minimal protein loss, rendering the tissue quasi-transparent. Along with sodium dodecylbenzene sulfonate and Triton X-100, aqueous solutions of Disodium laureth sulfosuccinate are popular for dispersing or suspending nanotubes, such as carbon nanotubes.
Niche uses
Disodium laureth sulfosuccinate has been proposed as a potentially effective topical microbicide, for intravaginal use, to inhibit and possibly prevent infection by various enveloped and non-enveloped viruses such as the herpes simplex viruses, HIV, and the Semliki Forest virus. In gas hydrate formation experiments, Disodium laureth sulfosuccinate is used as a gas hydrate growth promoter.Researchers aim for gas hydrate promotions as scale-up of industrial applications of gas hydrates such as desalination process, gas storage, and gas separation technologies. Liquid membranes formed from Disodium laureth sulfosuccinate in water have been demonstrated to work as unusual particle separators.The device acts as a reverse filter, allowing large particles to pass while capturing smaller particles.
Toxicology
Carcinogenicity
Disodium laureth sulfosuccinate is not carcinogenic when consumed or applied directly, even to amounts and concentrations that exceed amounts used in standard commercial products.The earlier review of the Cosmetic Ingredient Review (CIR) program Expert Panel in 1983 reported that Disodium laureth sulfosuccinate (there, abbreviated Disodium laureth sulfosuccinate , for Disodium laureth sulfosuccinate) in concentrations up to 2%, in a year-long oral dietary studies in dogs, gave no evidence of tumorigenicity or carcinogenicity, and that no excess chromosomal aberrations or clastogenic effects were observed in rats fed up to 1.13% Disodium laureth sulfosuccinate in their diets for 90 days, over those on a control diet.[28]:157, 175 The 2005 review by the same group indicated that further available data lacked any available suggestion that Disodium laureth sulfosuccinate or the related ammonium salt of the same amphiphile could be carcinogenic, stating that "Despite assertions to the contrary on the Internet, the carcinogenicity of these ingredients is only a rumor;" both studies conclude that Disodium laureth sulfosuccinate appears "to be safe in formulations designed for discontinuous, brief use followed by thorough rinsing from the surface of the skin. In products intended for prolonged contact with skin, concentrations should not exceed 1%.":89ff
Sensitivity
Like all detergent surfactants, Disodium laureth sulfosuccinate removes oils from the skin, and can cause skin and eye irritation.[citation needed] It has been shown to irritate the skin of the face, with prolonged and constant exposure (more than an hour) in young adults.Disodium laureth sulfosuccinate may worsen skin problems in individuals with chronic skin hypersensitivity, with some people being affected more than others.
Oral concerns
The low cost of Disodium laureth sulfosuccinate , its lack of impact on taste, its potential impact on volatile sulfur compounds (VSCs, which contribute to malodorous breath),[35] and its desirable action as a foaming agent have led to the use of Disodium laureth sulfosuccinate in the formulations of toothpastes.A series of small crossover studies (25-34 patients) have supported the efficacy of Disodium laureth sulfosuccinate in the reduction of VSCs, and its related positive impact on breath malodor, although these studies have been generally noted to reflect technical challenges in the control of study design variables. While primary sources from the group of Irma Rantanen at University of Turku, Finland conclude an impact on dry mouth (xerostomia) from Disodium laureth sulfosuccinate -containing pastes, a 2011 Cochrane review of these studies, and of the more general area, concludes that there "is no strong evidence... that any topical therapy is effective for relieving the symptom of dry mouth."[36] A safety concern has been raised on the basis of several studies regarding the effect of toothpaste Disodium laureth sulfosuccinate on aphthous ulcers, commonly referred to as canker or white sores. A consensus regarding practice (or change in practice) has not appeared as a result of the studies. As Lippert notes, of 2013, "very few... marketed toothpastes contain a surfactant other than Disodium laureth sulfosuccinate [Disodium laureth sulfosuccinate ]," and leading manufacturers continue to formulate their produce with Disodium laureth sulfosuccinate .
Interaction with fluoride
Some studies have suggested that Disodium laureth sulfosuccinate in toothpaste may decrease the effectiveness of fluoride at preventing dental caries (cavities). This may be due to Disodium laureth sulfosuccinate interacting with the deposition of fluoride on tooth enamel.
Use:
-Detergency: tooth paste, shampoo, cosmetic, detergent, etc.
-Construction: plasterboard, additive of concrete, coating, etc.
-Pharmaceutical: Medicine, pesticide, etc.
-Leather: leather soft agent, wool cleaning agent, etc.
-Paper making: penetrant, flocculating agent, deinking agent, etc.
-Auxiliaries: textile auxiliaries, plastic auxiliaries, etc.
-Fire fighting: oil well fire fighting, fire fighting device, etc.
-Mineral choosing: mine flotation, coal water mixture, etc.
Overview
Disodium laureth sulfosuccinate is one of the ingredients you'll find listed on your shampoo bottle. However, unless you're a chemist, you likely don't know what it is. The chemical is found in many cleaning and beauty products, but it's frequently misunderstood.
Urban myths have linked it to cancer, skin irritation, and more. Science may tell a different story.
How it works
Disodium laureth sulfosuccinate is what's known as a "surfactant." This means it lowers the surface tension between ingredients, which is why it's used as a cleansing and foaming agent.
Most concerns about Disodium laureth sulfosuccinate stem from the fact that it can be found in beauty and self-care products as well as in household cleaners.
Sodium laureth sulfate (SLES) is a surfactant with a similar chemical formula. However, SLES is milder and less irritating than Disodium laureth sulfosuccinate .
Where you'll find Disodium laureth sulfosuccinate
If you look under your bathroom sink, or on the shelf in your shower, it's very likely you'll find Disodium laureth sulfosuccinate in your home. It's used in a variety of products, including:
Grooming products, such as shaving cream, lip balm, hand sanitizer, nail treatments, makeup remover, foundation, facial cleansers, exfoliants, and liquid hand soap
Hair products, such as shampoo, conditioner, hair dye, dandruff treatment, and styling gel
Dental care products, such as toothpaste, teeth whitening products, and mouthwash
Bath products, such as bath oils or salts, body wash, and bubble bath
Creams and lotions, such as hand cream, masks, anti-itch creams, hair-removal products, and sunscreen
You'll notice that all of these products are topical, or applied directly to the skin or body.
Disodium laureth sulfosuccinate is also used as a food additive, usually as an emulsifier or a thickener. It can be found in dried egg products, some marshmallow products, and certain dry beverage bases.
Are there dangers?
The Food and Drug Administration (FDA) regards Disodium laureth sulfosuccinate as safe as a food additive.
Regarding its use in cosmetics and body products, the safety assessment study of Disodium laureth sulfosuccinate , published in 1983 in the International Journal of Toxicology (the most recent assessment), found that it's not harmful if used briefly and rinsed from the skin, as with shampoos and soaps.
The report says that products that stay on the skin longer shouldn't exceed 1 percent concentration of Disodium laureth sulfosuccinate .
However, the same assessment did suggest some possible, albeit minimal, risk to humans using Disodium laureth sulfosuccinate . For example, some tests found that continuous skin exposure to Disodium laureth sulfosuccinate could cause mild to moderate irritation in animals.
Nevertheless, the assessment concluded that Disodium laureth sulfosuccinate is safe in formulations used in cosmetics and personal care products. Because many of these products are designed to be rinsed off after short applications, the risks are minimal.
According to most research, Disodium laureth sulfosuccinate is an irritant but not a carcinogen. Studies have shown no link between the use of Disodium laureth sulfosuccinate and increased cancer risk.
According to a 2015 study, Disodium laureth sulfosuccinate is safe for use in household cleaning products.
Disodium laureth sulfosuccinate acts as a de-greasing, emulsifier, and a foaming agent which is used in many shampoos and other cleaning products. It is considered as a gentle cleansing ingredient for hair & skin.
Disodium laureth sulfosuccinate is classified as :
Cleansing
Foaming
Foam boosting
Hydrotrope
Surfactant
What Is Disodium laureth sulfosuccinate?
Disodium laureth sulfosuccinate is a surfactant. It is a disodium salt of ethoxylated lauryl alcohol bound to sulfosuccinic acid. Disodium laureth sulfosuccinate is primarily used in cleansing products, including bubble baths, bath soaps and detergents, shampoos and shaving cream.
Why is it used in cosmetics and personal care products?
In cosmetics and personal care products, Disodium laureth sulfosuccinate functions as a surfactant
cleansing agent, a surfactant
foam booster or a surfactant
hydrotrope.
Scientific Facts of Disodium laureth sulfosuccinate:
Disodium laureth sulfosuccinate is an anionic surfactant. This means that this ingredient has a negative charge. The negative charge is associated with the sulfosuccinate portion of the compound. Surfactants function by reducing the surface tension of water which makes it easier to wash dirt from the skin and hair.
DLSS - Disodium laureth sulfosuccinate is an anionic surfactant in White Powder form, also known as Plantapon SUS. Disodium laureth sulfosuccinate is considerably milder than Sodium Laureth Sulphate and it has excellent foaming and degreasing properties when used in a range of Bath products.
Disodium laureth sulfosuccinate is a gentle surfactant agent that cleanses skin and hair.
Description of Disodium laureth sulfosuccinate
All surfactants are partly water-soluble and partly oil-soluble, allowing oil and water-based ingredients to blend well. This means it will trap oil-based dirt from hair and skin and allow it to be easily rinsed away.
Disodium laureth sulfosuccinate is often used as a milder alternative to sulfates, although one doesn't systematically replace the other as they are not the same material and will not behave in the same way with other ingredients.
Disodium laureth sulfosuccinate is a sulfate-free anionic surfactant and ECOCERT approved. It is an excellent Foaming agent which produces a creamy rich lather in your products. Disodium laureth sulfosuccinate is considerably milder than SLS whilst still producing plenty of foam. Disodium laureth sulfosuccinate can be used in Shampoos, Bubble Bath products, Bath Bombs, Liquid Soap bases, Soap Bars and Body Wash Bases. Please be aware this is a very fine powder, so use in a well-ventilated area when decanting and manufacturing your products.
Description of Disodium laureth sulfosuccinate: Very mild anionic co-surfactant, highly water soluble in a wide pH range, pH: 6.5 - 7.5 (in 5% aqueous solution). Contains 32% active substances. Preservative benzoic acid. Clear yellow liquid, no or faint odor.
CAS of Disodium laureth sulfosuccinate: 39354-45-5
INCI Name: Disodium laureth sulfosuccinate
Benefits of Disodium laureth sulfosuccinate:
Very mild co-surfactant compatible with anionic, nonionic, amphoteric surfactants
Useful also as primary surfactant due to its good foaming and cleansing properties
Especially suitable for products for delicate skin and baby shampoos,
Has good emulsifying properties (useful as secondary o/w emulsifier)
Use of Disodium laureth sulfosuccinate: Can be added to formulas as is. Recommended use level 4 - 40% depending on desired foaming and cleansing effects. For external use only.
Applications of Disodium laureth sulfosuccinate: Body washes, shampoos, bubble baths, cleansing lotions, creams, hand soaps, baby products, hair conditioners, cream rinses.
Country of Origin: USA
Raw material source of Disodium laureth sulfosuccinate: Coconut oil and sulfosuccinic acid
Manufacture of Disodium laureth sulfosuccinate: Sulfosuccinate is produced by reacting coconut-oil derived ethoxylated lauryl alcohol with sulfosuccinic acid which is made from maleic anhydride followed by addition of sodium bisulfite.
Animal Testing of Disodium laureth sulfosuccinate: Not animal tested
Disodium laureth sulfosuccinate (sodium dodecyl sulphate) is a kind of anionic surfactant, dissolves in the water easily, compatibility with anion and non-ionic, good performances on emulsifying, foaming, osmosis, detergency and de-centrality. Disodium laureth sulfosuccinate Powder Disodium laureth sulfosuccinate Powder is a widely used surfactant often used as a foaming agent in many common products like Bath products, shampoos, foaming powders and mony industrial and commercial cleaners. SaveonCitric offers a highly Active, high quality Disodium laureth sulfosuccinate Powdered Disodium laureth sulfosuccinate. If you are formulating a product like a powdered or tablet cleanser, or blending liquid hard surface or carpet cleaners, try Disodium laureth sulfosuccinate Powder. Check the FIFRa list if you are formulating blends and looking for an accepted surfactant. Sodium dodecyl sulfate , synonymously, Disodium laureth sulfosuccinate , or sodium laurilsulfate, is a synthetic organic compound with the formula CH3(CH2)11SO4Na. It is an anionic surfactant used in many cleaning and hygiene products. The sodium salt is of an organosulfate class of organics. It consists of a 12-carbon tail attached to a sulfate group, that is, it is the sodium salt of dodecyl hydrogen sulfate, the ester of dodecyl alcohol and sulfuric acid. Its hydrocarbon tail combined with a polar "headgroup" give the compound amphiphilic properties and so make it useful as a detergent.[not verified in body] Also derived as a component of mixtures produced from inexpensive coconut and palm oils, Disodium laureth sulfosuccinate is a common component of many domestic cleaning, personal hygiene and cosmetic, pharmaceutical, and food products, as well as of industrial and commercial cleaning and product formulations. Disodium laureth sulfosuccinate is a widely used surfactant in cleaning products, cosmetic, and personal care products. Disodium laureth sulfosuccinate 's uses in these products have been thoroughly evaluated and determined to be safe for consumers and the environment. Disodium laureth sulfosuccinate , sodium laurilsulfate or sodium dodecyl sulfate (Disodium laureth sulfosuccinate or NaDS) (C12H25SO4Na) is an anionic surfactant used as an emulsifying cleaning agent in many cleaning and hygiene products. Disodium laureth sulfosuccinate is a highly effective surfactant and is used in any task requiring the removal of oily stains and residues. For example, it is found in higher concentrations with industrial products including engine degreasers, floor cleaners, and car wash soaps. It is used in lower concentrations with toothpastes, shampoos, and shaving foams. It is an important component in bubble bath formulations for its thickening effect and its ability to create a lather.
WHAT IS Disodium laureth sulfosuccinate ?
Disodium laureth sulfosuccinate , also known as Sodium dodecyl sulfate, is a widely used surfactant in cleaning products, cosmetics, and personal care products. The Disodium laureth sulfosuccinate formula is a highly effective anionic surfactant used to remove oily stains and residues. It is found in high concentrations in industrial products, including engine degreasers, floor cleaners, and car wash products, where workplace protections can be implemented to avoid unsafe exposures. Disodium laureth sulfosuccinate is also used in lower concentrations in household and personal care products such as cleaning products, toothpastes, shampoos, and shaving foams.
SAFETY
Disodium laureth sulfosuccinate has been thoroughly reviewed for its safety by a number of governments. For example:
Based on a thorough safety review, including consideration of chronic risks, the U.S. Environmental Protection Agency (EPA) has issued an exemption for
Disodium laureth sulfosuccinate from the requirement of tolerance for residues when used as a component of food contact sanitizing solutions applied to all food contact surfaces in public eating places, dairy-processing equipment, and food-processing equipment and utensils at a maximum level in the end-use concentration of 350 parts per million (ppm). The regulation eliminates the need to establish a maximum permissible level for residues of Disodium laureth sulfosuccinate. The Food and Drug Administration (FDA) includes Disodium laureth sulfosuccinate on its list of multipurpose additives allowed to be directly added to food. Disodium laureth sulfosuccinate and Ammonium Lauryl Sulfate are also approved indirect food additives. For example, both ingredients are permitted to be used as components of coatings. Disodium laureth sulfosuccinate and Ammonium Lauryl Sulfate may be used in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Directive of the European Union. The Organization of Economic Cooperation and Development, which is an organization of 30-plus developed countries, has reviewed the human and environmental hazards of a category of chemicals that includes Disodium laureth sulfosuccinate. No chronic human health hazards, including carcinogenicity, were identified. The hazard assessment for the category (alkyl sulphates, alkane sulphonates and alpha-olefin sulphonates category) is posted on the OECD website.
Disodium laureth sulfosuccinate has also been thoroughly reviewed for human safety by an industry funded, independent panel, which found: There is no evidence of harm from the use of Disodium laureth sulfosuccinate in cosmetic products, where there is intentional, direct contact with the skin. The ingredient was reviewed in 1983 and re-reviewed in 2005 by the Cosmetic Ingredient Review (CIR)1 Expert Panel and found to be safe for use in cosmetic and personal care products. Disodium laureth sulfosuccinate can cause skin irritation in some persons, which is one reason why it is important to follow the label instructions when using a cleaning product. A complete report on Disodium laureth sulfosuccinate is available from CIR.
Structure
Disodium laureth sulfosuccinate is in the family of organosulfate compounds,[2] and has the formula, CH3(CH2)11SO4Na. It consists of a 12-carbon tail attached to a sulfate group, that is, it is the sodium salt of a 12-carbon alcohol that has been esterified to sulfuric acid. An alternative description is that it is an alkyl group with a pendant, terminal sulfate group attached. As a result of its hydrocarbon tail, and its anionic "head group", it has amphiphilic properties that allow it to form micelles, and so act as a detergent.
Physicochemical properties
The critical micelle concentration (CMC) in pure water at 25 °C is 8.2 mM,[1] and the aggregation number at this concentration is usually considered to be about 62.[3] The micelle ionization fraction (α) is around 0.3 (or 30%).[4]
Production
Disodium laureth sulfosuccinate is synthesized by treating lauryl alcohol with sulfur trioxide gas, oleum, or chlorosulfuric acid to produce hydrogen lauryl sulfate.[5] The resulting product is then neutralized through the addition of sodium hydroxide or sodium carbonate.[citation needed] Lauryl alcohol can be used in pure form or may be derived from either coconut or palm kernel oil by hydrolysis (which liberates their fatty acids), followed by hydrogenation.[citation needed] When produced from these sources, commercial samples of these "Disodium laureth sulfosuccinate " products are actually not pure Disodium laureth sulfosuccinate , rather a mixture of various sodium alkyl sulfates with Disodium laureth sulfosuccinate being the main component.[6] For instance, Disodium laureth sulfosuccinate is a component, along with other chain-length amphiphiles, when produced from coconut oil, and is known as sodium coco sulfate (SCS).[7] Disodium laureth sulfosuccinate is available commercially in powder, pellet, and other forms (each differing in rates of dissolution), as well as in aqueous solutions of varying concentrations.
DESCRIPTION: Anionic surfactant. Vegetable origin. Solid (powder form). Disodium laureth sulfosuccinate, also called Sodium dodecyl sulfate, is a surfactant used in many cleaning and hygiene products such as toothpastes, shampoos, and bubble baths. (flammable solid)
Applications
Cleaning and hygiene
Disodium laureth sulfosuccinate is mainly used in detergents for laundry with many cleaning applications.It is a highly effective surfactant and is used in any task requiring the removal of oily stains and residues; for example, Disodium laureth sulfosuccinate is found in higher concentrations with industrial products including engine degreasers, floor cleaners, and car wash soaps.In lower concentrations, it is found in toothpastes, shampoos, shaving creams, and bubble bath formulations, for its ability to create a foam (lather), for its surfactant properties, and in part for its thickening effect.[10]
Food additive
Disodium laureth sulfosuccinate, appearing as its synonym Disodium laureth sulfosuccinate , is considered as a generally recognized as safe (GRAS) ingredient, for food use according to the guidelines published in 21 CFR 172.822. It is used as an emulsifying agent and whipping aid. Disodium laureth sulfosuccinate is reported to temporarily diminish perception of sweetness.
Laboratory applications
Principal applications
Disodium laureth sulfosuccinate, in science referred to as sodium dodecyl sulfate , is used in cleaning procedures, and is commonly used as a component for lysing cells during RNA extraction and/or DNA extraction, and for denaturing proteins in preparation for electrophoresis in the Disodium laureth sulfosuccinate -PAGE technique. In the case of the Disodium laureth sulfosuccinate -PAGE application, the compound works by disrupting non-covalent bonds in the proteins, and so denaturing them, i.e., causing the protein molecules to lose their native conformations and shapes.[citation needed] By binding to the proteins with high affinity and in high concentrations, the negatively charged detergent provides all proteins with a similar net negative charge and therefore a similar charge-to-mass ratio. In this way, the difference in mobility of the polypeptide chains in the gel can be attributed solely to their size as opposed to both their size and charge.[16] It is possible to make separation based on the size of the polypeptide chain to simplify the analysis of protein molecules, this can be achieved by denaturing proteins with the detergent Disodium laureth sulfosuccinate .The association of Disodium laureth sulfosuccinate molecules with protein molecules imparts an associated negative charge to the molecular aggregate formed;[citation needed] this negative charge is significantly greater than the original charge of that protein.[citation needed] The electrostatic repulsion that is created by Disodium laureth sulfosuccinate binding forces proteins into a rod-like shape, thereby eliminating differences in shape as a factor for electrophoretic separation in gels.[citation needed] Dodecyl sulfate molecule has two negative charges at the pH value used for electrophoresis, this will lead the net charge of coated polypeptide chains to be much more negative than uncoated chains.[17] The charge-to-mass ratio is essentially identical for different proteins because Disodium laureth sulfosuccinate coating dominates the charge.
Miscellaneous applications
Disodium laureth sulfosuccinate is used in an improved technique for preparing brain tissues for study by optical microscopy. The technique, which has been branded as CLARITY, was the work of Karl Deisseroth and coworkers at Stanford University, and involves infusion of the organ with an acrylamide solution to bind the macromolecules of the organ (proteins, nucleic acids, etc.), followed by thermal polymerization to form a "brain-hydrogel" (a mesh interspersed throughout the tissue to fix the macromolecules and other structures in space), and then by lipid removal using Disodium laureth sulfosuccinate to eliminate light scattering with minimal protein loss, rendering the tissue quasi-transparent. Along with sodium dodecylbenzene sulfonate and Triton X-100, aqueous solutions of Disodium laureth sulfosuccinate are popular for dispersing or suspending nanotubes, such as carbon nanotubes.
Niche uses
Disodium laureth sulfosuccinate has been proposed as a potentially effective topical microbicide, for intravaginal use, to inhibit and possibly prevent infection by various enveloped and non-enveloped viruses such as the herpes simplex viruses, HIV, and the Semliki Forest virus. In gas hydrate formation experiments, Disodium laureth sulfosuccinate is used as a gas hydrate growth promoter.Researchers aim for gas hydrate promotions as scale-up of industrial applications of gas hydrates such as desalination process, gas storage, and gas separation technologies. Liquid membranes formed from Disodium laureth sulfosuccinate in water have been demonstrated to work as unusual particle separators.The device acts as a reverse filter, allowing large particles to pass while capturing smaller particles.
Toxicology
Carcinogenicity
Disodium laureth sulfosuccinate is not carcinogenic when consumed or applied directly, even to amounts and concentrations that exceed amounts used in standard commercial products.The earlier review of the Cosmetic Ingredient Review (CIR) program Expert Panel in 1983 reported that Disodium laureth sulfosuccinate (there, abbreviated Disodium laureth sulfosuccinate , for Disodium laureth sulfosuccinate) in concentrations up to 2%, in a year-long oral dietary studies in dogs, gave no evidence of tumorigenicity or carcinogenicity, and that no excess chromosomal aberrations or clastogenic effects were observed in rats fed up to 1.13% Disodium laureth sulfosuccinate in their diets for 90 days, over those on a control diet.[28]:157, 175 The 2005 review by the same group indicated that further available data lacked any available suggestion that Disodium laureth sulfosuccinate or the related ammonium salt of the same amphiphile could be carcinogenic, stating that "Despite assertions to the contrary on the Internet, the carcinogenicity of these ingredients is only a rumor;" both studies conclude that Disodium laureth sulfosuccinate appears "to be safe in formulations designed for discontinuous, brief use followed by thorough rinsing from the surface of the skin. In products intended for prolonged contact with skin, concentrations should not exceed 1%.":89ff
Sensitivity
Like all detergent surfactants, Disodium laureth sulfosuccinate removes oils from the skin, and can cause skin and eye irritation.[citation needed] It has been shown to irritate the skin of the face, with prolonged and constant exposure (more than an hour) in young adults.Disodium laureth sulfosuccinate may worsen skin problems in individuals with chronic skin hypersensitivity, with some people being affected more than others.
Oral concerns
The low cost of Disodium laureth sulfosuccinate , its lack of impact on taste, its potential impact on volatile sulfur compounds (VSCs, which contribute to malodorous breath),[35] and its desirable action as a foaming agent have led to the use of Disodium laureth sulfosuccinate in the formulations of toothpastes.A series of small crossover studies (25-34 patients) have supported the efficacy of Disodium laureth sulfosuccinate in the reduction of VSCs, and its related positive impact on breath malodor, although these studies have been generally noted to reflect technical challenges in the control of study design variables. While primary sources from the group of Irma Rantanen at University of Turku, Finland conclude an impact on dry mouth (xerostomia) from Disodium laureth sulfosuccinate -containing pastes, a 2011 Cochrane review of these studies, and of the more general area, concludes that there "is no strong evidence... that any topical therapy is effective for relieving the symptom of dry mouth."[36] A safety concern has been raised on the basis of several studies regarding the effect of toothpaste Disodium laureth sulfosuccinate on aphthous ulcers, commonly referred to as canker or white sores. A consensus regarding practice (or change in practice) has not appeared as a result of the studies. As Lippert notes, of 2013, "very few... marketed toothpastes contain a surfactant other than Disodium laureth sulfosuccinate [Disodium laureth sulfosuccinate ]," and leading manufacturers continue to formulate their produce with Disodium laureth sulfosuccinate .
Interaction with fluoride
Some studies have suggested that Disodium laureth sulfosuccinate in toothpaste may decrease the effectiveness of fluoride at preventing dental caries (cavities). This may be due to Disodium laureth sulfosuccinate interacting with the deposition of fluoride on tooth enamel.
Use:
-Detergency: tooth paste, shampoo, cosmetic, detergent, etc.
-Construction: plasterboard, additive of concrete, coating, etc.
-Pharmaceutical: Medicine, pesticide, etc.
-Leather: leather soft agent, wool cleaning agent, etc.
-Paper making: penetrant, flocculating agent, deinking agent, etc.
-Auxiliaries: textile auxiliaries, plastic auxiliaries, etc.
-Fire fighting: oil well fire fighting, fire fighting device, etc.
-Mineral choosing: mine flotation, coal water mixture, etc.
Overview
Disodium laureth sulfosuccinate is one of the ingredients you'll find listed on your shampoo bottle. However, unless you're a chemist, you likely don't know what it is. The chemical is found in many cleaning and beauty products, but it's frequently misunderstood.
Urban myths have linked it to cancer, skin irritation, and more. Science may tell a different story.
How it works
Disodium laureth sulfosuccinate is what's known as a "surfactant." This means it lowers the surface tension between ingredients, which is why it's used as a cleansing and foaming agent.
Most concerns about Disodium laureth sulfosuccinate stem from the fact that it can be found in beauty and self-care products as well as in household cleaners.
Sodium laureth sulfate (SLES) is a surfactant with a similar chemical formula. However, SLES is milder and less irritating than Disodium laureth sulfosuccinate .
Where you'll find Disodium laureth sulfosuccinate
If you look under your bathroom sink, or on the shelf in your shower, it's very likely you'll find Disodium laureth sulfosuccinate in your home. It's used in a variety of products, including:
Grooming products, such as shaving cream, lip balm, hand sanitizer, nail treatments, makeup remover, foundation, facial cleansers, exfoliants, and liquid hand soap
Hair products, such as shampoo, conditioner, hair dye, dandruff treatment, and styling gel
Dental care products, such as toothpaste, teeth whitening products, and mouthwash
Bath products, such as bath oils or salts, body wash, and bubble bath
Creams and lotions, such as hand cream, masks, anti-itch creams, hair-removal products, and sunscreen
You'll notice that all of these products are topical, or applied directly to the skin or body.
Disodium laureth sulfosuccinate is also used as a food additive, usually as an emulsifier or a thickener. It can be found in dried egg products, some marshmallow products, and certain dry beverage bases.
Are there dangers?
The Food and Drug Administration (FDA) regards Disodium laureth sulfosuccinate as safe as a food additive.
Regarding its use in cosmetics and body products, the safety assessment study of Disodium laureth sulfosuccinate , published in 1983 in the International Journal of Toxicology (the most recent assessment), found that it's not harmful if used briefly and rinsed from the skin, as with shampoos and soaps.
The report says that products that stay on the skin longer shouldn't exceed 1 percent concentration of Disodium laureth sulfosuccinate .
However, the same assessment did suggest some possible, albeit minimal, risk to humans using Disodium laureth sulfosuccinate . For example, some tests found that continuous skin exposure to Disodium laureth sulfosuccinate could cause mild to moderate irritation in animals.
Nevertheless, the assessment concluded that Disodium laureth sulfosuccinate is safe in formulations used in cosmetics and personal care products. Because many of these products are designed to be rinsed off after short applications, the risks are minimal.
According to most research, Disodium laureth sulfosuccinate is an irritant but not a carcinogen. Studies have shown no link between the use of Disodium laureth sulfosuccinate and increased cancer risk.
According to a 2015 study, Disodium laureth sulfosuccinate is safe for use in household cleaning products.
