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Disodium lauriminodipropionate is a disodium salt of a complexmixture of esters formed by the reaction of Tocopherol Phosphate (q.v.) and Lauriminodipropionic Acid(q.v.).
Disodium lauriminodipropionate is also known as DLTP is the disodium salt of a mixture of esters made from lauriminodipropionic acid and tocopherol phosphate.
Disodium lauriminodipropionate is also known as amphoteric surfactant meaning it has both the acidic and basic group in its structure.
CAS Number: 3655-00-3
Molecular Formula: C18H33NNa2O4
Molecular Weight: 373.43846
EINECS Number: 222-899-0
Synonyms: 3655-00-3, DISODIUM LAURIMINODIPROPIONATE, Deriphat 160, UNII-KAS63U0A87, KAS63U0A87, COLATERIC HFA, Sodium N-dodecyliminodipropionate, HSDB 2790, REWOTERIC AM-LP, MIRATAINE H 2C, beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, disodium salt, EINECS 222-899-0, Sodium N-lauryl-beta-iminodipropionate, disodium;3-[2-carboxylatoethyl(dodecyl)amino]propanoate, Propionic acid, 3,3'-(dodecylimino)di-, disodium salt, N-Lauryl-beta-iminodipropionate sodium salt, Disodium 3,3'-(dodecylimino)bis(propionate), Disodium beta,beta'-(laurylimino)dipropionate, DTXSID9063116, .beta.-Alanine, N-(2-carboxyethyl)-N-dodecyl-, disodium salt, Disodium N-lauryl-beta,beta'-iminodipropionate, 26256-79-1, Disodium N-lauryl-beta-iminodipropionate, DISODIUM LAURIMINODIPROPIONATE [HSDB], DISODIUM 3,3'-(DODECYLIMINO)DIPROPIONATE, DISODIUM N-LAURYL-.BETA.-IMINODIPROPIONATE, N-(2-Carboxyethyl)-N-dodecyl-beta-alanine, disodium salt, beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, sodium salt (1:2), .beta.-Alanine, N-(2-carboxyethyl)-N-dodecyl-, sodium salt (1:2), N-(2-CARBOXYETHYL)-N-DODECYL-.BETA.-ALANINE, DISODIUM SALT, SCHEMBL337202, Sodium Ndodecyliminodipropionate, Disodium N-(2-carboxyethyl)-N-dodecyl-beta-alaninate, DTXCID0039194, KSDGSKVLUHKDAL-UHFFFAOYSA-L, N-dodecyliminodipropionate disodium, Sodium Nlaurylbetaiminodipropionate, Disodium Nlaurylbetaiminodipropionate, NLaurylbetaiminodipropionate sodium salt, Sodium3,3'-(dodecylazanediyl)dipropanoate, Disodium Nlaurylbeta,beta'iminodipropionate, Disodium 3,3'(dodecylimino)bis(propionate), Disodium beta,beta'(laurylimino)dipropionate, Sodium 3,3'-(dodecylazanediyl)dipropanoate, Sodium 3,3'-(dodecylazanediyl)dipropionate, CS-0451700, DISODIUM LAURIMINODIPROPIONATE [INCI], N-(2-Carboxyethyl)-N-lauryl-.beta.-alanine, G77834, 3,3'-(Dodecylimino)dipropionic acid sodium salt, 3,3'-(Dodecylimino)dipropionic acid,sodium salt, N(2Carboxyethyl)Ndodecylbetaalanine, disodium salt, betaAlanine, N(2carboxyethyl)Ndodecyl, disodium salt, W-110652, Propionic acid, 3,3'(dodecylimino)di, disodium salt, Q27282156, N-(2-Carboxyethyl)-N-dodecyl-β-alaninate disodium salt;N-DODECYL-B-IMINODIPROPIONIC ACID, DISODIUM SALT, ANAGRADE?;disodium N-(2-carboxyethyl)-N-dodecyl-beta-alaninate;DISODIUM LAURIMINODIPROPIONATE;N-lauryl-beta-iminopropionic acid, disodium salt;N-DODECYL-B-IMINODIPROPIONIC ACID;3,3'-(Dodecylimino)bis(propionic acid sodium) salt;3,3'-Dodecyliminobispropanoic acid disodium salt
Disodium lauriminodipropionate is particularly important because it can hold both acidic and basic groups tide together and exert its effects more efficiently.
Also, Vitamin E or tocopherol derivative is an added benefit in this molecule and can serve multifold purposes.
A bio-available derivative of famous antioxidant, Vitamin E that's claimed to reduce the appearance of skin redness caused by various external skin aggressions such as acne, razor burn or UV light.
Disodium lauriminodipropionate is a chemical compound that functions as a surfactant and emulsifying agent, widely used in personal care, cosmetic, and industrial formulations.
Disodium lauriminodipropionate is a disodium salt derived from laurylamine, a fatty amine, and dipropionic acid, which results in a molecule with a hydrophobic tail (the lauryl group) and hydrophilic head (the propionate group).
This unique structure allows disodium lauriminodipropionate to reduce the surface tension of water, making it an effective ingredient in products designed to clean, condition, or emulsify.
In personal care products, Disodium lauriminodipropionate is primarily used for its mild cleansing properties.
It is often included in formulations for shampoos, facial cleansers, body washes, and other skincare products where it helps remove dirt, oils, and impurities from the skin and hair.
Its mildness makes it suitable for sensitive skin, as it does not typically cause irritation or dryness compared to harsher surfactants like sulfates.
In addition to its cleansing capabilities, Disodium lauriminodipropionate functions as an emulsifier in cosmetic formulations. This allows it to stabilize mixtures of oil and water, which is particularly important in the formulation of lotions, creams, and other products where both types of ingredients must be blended and remain stable over time. Its ability to form stable emulsions makes it an essential ingredient in the cosmetic and pharmaceutical industries, ensuring that products perform consistently throughout their use.
Beyond cosmetics, Disodium lauriminodipropionate is also used in industrial applications.
In these contexts, it can serve as a wetting agent, dispersing agent, or emulsifier in processes that require the mixing of hydrophobic and hydrophilic substances.
This includes its use in cleaning agents, paints, coatings, and detergents, where it helps ensure uniform distribution of ingredients and improves the effectiveness of the final product.
While generally considered to be safe for use in cosmetics and other formulations, Disodium lauriminodipropionate should still be handled with care, as excessive exposure or misuse could lead to mild skin irritation in some individuals.
Proper storage and handling according to manufacturer guidelines are important to maintain product stability and safety.
Disodium lauriminodipropionatel is stored in the liver and adipose tissue.
In the liver it is bound and transferred by a specific cytosolic protein, α-tocopherol transfer protein (α−TTP).
When circulated through plasma, tocopherol is transported by several forms of lipoproteins including very low density lipoproteins (VLDL) and high density lipoproteins (HDL).
It is believed that most α-tocopherol is delivered through HDLs to cells for use in the membrane or within the cell.
Disodium lauriminodipropionate is not unreasonable to assume that when delivered topically, α- tocopherol needs to associate with a transport protein to gain access to the dermis, especially the fibroblasts, unless some other delivery vehicle is provided in the formulation.
Another significant formulation challenge is to keep α- tocopherol stable until use.
The most common approach is to use the ester α-tocopherol acetate.
Although the ester is more stable than α-tocopherol, it has a different efficacy profile.
For instance, it has been shown that α-Disodium lauriminodipropionate binds α- tocopherol to an extent more than 50 times greater than α- tocopherol acetate.
A second approach to vitamin and drug stabilization is phosphorylation.
Disodium lauriminodipropionate is the transformation of an alcohol to a phosphate ester through transfer of a phosphoryl group (-PO3H2).
Disodium lauriminodipropionate is the most common endogenous phosphorylating agent.
It has been shown that phosphorylated vitamin C is accumulated into cells as vitamin C.
Work in our laboratories has begun to develop evidence for the presence of phosphorylated α-tocopherol in the human body.
For this reason, we believe that phosphorylation is a better route to formulation stabilization and that it allows a better opportunity for in vivo efficacy through an endogenous form that can be activated by phosphate ester cleavage.
CAS DataBase Reference: 3655-00-3
EWG's Food Scores: 1
FDA UNII: KAS63U0A87
Density: 1.11[at 20℃]
solubility: 2.39g/L in organic solvents at 20 ℃
pka: 1.14[at 20 ℃]
LogP: 5.520 (est)
Disodium lauriminodipropionate is a complex mixture of esters formed from a blend of tocopherol phosphates with lauriminodipropionic acid.
This blend is part natural, part synthetic and has multiple functions, including as a cleansing agent. Lauriminodipropionic acid is a propionic acid, a natural acid that is part of the degraded contents of sugar.
Disodium lauriminodipropionate has mild preservative properties.
The molecule altogether when incorporated in any formulation, it helps in reducing redness on the skin.
Redness can affect the skin because of various reasons, either skin becomes extremely dry is one reason, another if it has been exposed to sunlight for a prolonged period of time or some mild allergic reaction to another ingredient, either alone or combination of these reasons can make the skin red and inflamed.
Disodium lauriminodipropionate is used in any formulation, it soothes skin and helps the skin recover faster.
It is as effective for sensitive skin also.
Many times, when acne troubled skin has acne-related lesions as well, it can get more irritated easily because of bacteria and other factors like dirt, chemicals.
In that case, also, DLTP can help relieve the skin trouble by soothing and curing it.
The cuts after shaving and discomfort related to that can be encountered more frequently, which brings an annoying feeling of pain and redness.
Disodium lauriminodipropionate comes in to picture and noticeably faster recovery can be achieved.
Disodium lauriminodipropionate is used in facial care, body care, and color cosmetics.
Surfactants are so-called detergent substances and have a major significance in cosmetics for the cleansing of the skin and hair.
Surfactants are substances which, based on their molecular structure, are able to reduce the surface tension of a liquid.
In this way Disodium lauriminodipropionate is possible that two actually not mixable substances, such as oil and water, can be finely mixed.
Because of their properties, surfactants have manifold uses in cosmetics: they can cleanse, produce foam and act as emulsifiers and mix substances with one another.
In shampoos, shower gels and soaps, surfactants are, for instance, used to wash fat and soil particles with water off from the body.
Surfactants are also used in toothpaste.
Here they promote during tooth cleaning the rapid and full dissolution and distribution of the paste in the mouth.
Disodium lauriminodipropionate is a specialized surfactant with a variety of roles in both consumer and industrial applications due to its unique chemical structure and properties.
The compound is derived by reacting laurylamine, a fatty amine sourced from coconut or palm kernel oils, with dipropionic acid.
This process creates a disodium salt that has both hydrophilic (water-attracting) and hydrophobic (water-repelling) properties, making it highly effective in both emulsifying and cleansing applications.
The emulsifying properties of disodium lauriminodipropionate are particularly important in products that require the combination of oil and water-based ingredients.
Disodium lauriminodipropionate forms stable emulsions, which helps ensure that oil and water phases stay uniformly mixed and do not separate over time.
This characteristic is vital in the formulation of creams, lotions, and sunscreens, where a smooth, consistent texture is essential for both the product's performance and aesthetic appeal.
Disodium lauriminodipropionates presence in these formulations can improve the product’s stability and extend its shelf life by preventing ingredient separation.
Another significant property of disodium lauriminodipropionate is its mildness, which makes it an ideal ingredient in formulations for sensitive skin.
Unlike harsher surfactants such as sodium lauryl sulfate, it does not strip the skin of its natural oils, reducing the risk of irritation or dryness.
This is particularly beneficial in products like baby shampoos, facial cleansers, and body washes, where a gentle cleaning agent is necessary.
Additionally, Disodium lauriminodipropionates mildness extends to being less likely to disrupt the skin's natural pH balance, further promoting its suitability for use in sensitive skin care products.
The cleansing function of disodium lauriminodipropionate is central to its inclusion in many personal care products.
In shampoos and facial cleansers, it helps break down oils, dirt, and impurities, allowing them to be easily washed away with water. Its ability to effectively lift away debris while being gentle on the skin or hair makes it a preferred choice for products aimed at delivering both deep cleaning and skin or hair conditioning without causing harsh or drying effects.
In industrial applications, the compound is often used as a wetting agent, which enhances the ability of water to spread across surfaces, improving the effectiveness of cleaning solutions, paint formulations, and other industrial chemicals.
Disodium lauriminodipropionate’s ability to disperse substances and ensure uniform mixing is crucial in manufacturing environments where consistency and product performance are paramount.
Disodium lauriminodipropionate is also used in textile processing to improve the quality of fabric treatments, such as in dyes and finishes, by ensuring even distribution of chemical agents on fabrics.
In addition to its effectiveness in consumer products, disodium lauriminodipropionate is biodegradable, which means it breaks down relatively easily in the environment.
This characteristic is important in the context of growing environmental awareness and the increasing demand for sustainable and eco-friendly products.
By using biodegradable surfactants like disodium lauriminodipropionate, companies can reduce the environmental impact of their products.
While generally recognized as safe in cosmetic formulations, disodium lauriminodipropionate should still be used in accordance with recommended concentrations and guidelines to avoid adverse effects such as skin sensitivity or irritation in some individuals.
As with any surfactant or emulsifier, excessive amounts or improper use could lead to mild irritation or allergic reactions in sensitive individuals.
Therefore, patch testing is always recommended for people with sensitive skin before using products containing this ingredient.
Uses Of Disodium lauriminodipropionate:
Disodium lauriminodipropionate is a surfactant with cleansing and foaming properties.
Disodium lauriminodipropionate has a wide range of uses, primarily in the personal care, cosmetics, and industrial sectors, owing to its effective surfactant and emulsifying properties.
One of its primary applications is in personal care products, particularly in shampoos, facial cleansers, body washes, and other skincare products, where it serves as a gentle surfactant.
In these formulations, it helps to cleanse the skin and hair by reducing surface tension, allowing oils, dirt, and impurities to be easily washed away.
Its mild nature makes it especially suitable for sensitive skin, as it cleans without causing irritation, dryness, or damage to the skin’s natural barrier.
In cosmetic formulations, disodium lauriminodipropionate functions as an emulsifying agent, enabling the stable mixing of water and oil-based ingredients.
This is crucial in products like lotions, creams, sunscreens, and moisturizers, where it ensures that the mixture remains stable over time without separating.
By forming smooth, consistent emulsions, it improves the texture and aesthetic appeal of these products, providing consumers with a product that is easy to apply and has a pleasant feel on the skin.
The mild cleansing properties of disodium lauriminodipropionate are also valuable in baby care products, such as baby shampoos and body washes.
Since these products are designed to be extra-gentle on sensitive skin, disodium lauriminodipropionate is an ideal ingredient because it effectively cleans without stripping moisture or causing irritation, making it a key component in baby-friendly formulations.
In industrial applications, disodium lauriminodipropionate is used as a wetting agent and emulsifier.
Its ability to reduce the surface tension of water helps it to spread evenly over surfaces, improving the effectiveness of cleaning solutions, detergents, and industrial cleaning agents.
This makes it useful in manufacturing processes where consistent and efficient cleaning or surface preparation is required. Additionally, disodium lauriminodipropionate’s emulsifying ability is beneficial in industries such as paint and coating production, where it helps in the mixing of water and oil components to create uniform and stable products.
Disodium lauriminodipropionate also plays a role in the textile industry, where it is used in fabric processing to enhance the quality and consistency of dyeing and finishing treatments.
By improving the distribution of chemicals across fabrics, disodium lauriminodipropionate helps to ensure that the final product has even coloring and texture, reducing the risk of imperfections or inconsistencies in the fabric's appearance and feel.
In household cleaning products, such as detergents and surface cleaners, disodium lauriminodipropionate is valued for its ability to emulsify oils and grease, helping to break down stubborn stains and residues for easier removal.
Its use in these products improves cleaning efficiency and ensures that the product is effective without being overly harsh on surfaces or hands.
Another notable application is in pharmaceutical formulations, where disodium lauriminodipropionate may be used as a solubilizing agent to help incorporate active ingredients into aqueous solutions.
This is particularly useful in the development of topical treatments or oral care products where the even distribution of medicinal or active ingredients is critical for efficacy.
Disodium lauriminodipropionate is also used in sustainable product formulations due to its biodegradable nature, making it an attractive choice for companies focused on reducing environmental impact.
By incorporating this surfactant into products, manufacturers can create more eco-friendly products that break down more easily in the environment, aligning with consumer demand for greener, more sustainable options.
In addition to its widespread use in personal care, cosmetics, and industrial applications, disodium lauriminodipropionate has further specialized uses that extend into various other sectors.
Its unique properties also lend themselves well to food processing, agriculture, and even pharmaceutical formulations, expanding its versatility beyond conventional applications.
In food processing, disodium lauriminodipropionate can act as a food-grade emulsifier. Emulsifiers are essential for ensuring the even distribution of fat and water in food products, which helps to improve texture, consistency, and stability.
Disodium lauriminodipropionate can be used in certain processed foods like salad dressings, sauces, and beverages where oil and water phases need to be combined without separating over time.
This ingredient helps achieve a smooth, uniform consistency, which is crucial for both consumer appeal and product shelf-life.
Additionally, its use in food products is regulated, ensuring that it is safe for human consumption and complies with food safety standards.
In the agriculture industry, disodium lauriminodipropionate can be utilized as a wetting agent in the formulation of pesticides, herbicides, and fungicides.
Disodium lauriminodipropionate helps improve the spread and coverage of the chemicals on plant surfaces, ensuring more effective application and better absorption.
By enhancing the spreadability and penetration of these active ingredients, it can increase the efficacy of crop protection products while reducing waste and the need for excessive chemical use.
Disodium lauriminodipropionates role as a surfactant can also help in the formulation of fertilizers, where uniform distribution across plant foliage is essential for optimal nutrient absorption.
In pharmaceutical formulations, disodium lauriminodipropionate can be employed as a stabilizer and solubilizer for various medicinal compounds.
Disodium lauriminodipropionate aids in the uniform mixing of both hydrophilic and hydrophobic ingredients, which is crucial for achieving consistent drug delivery in topical creams, ointments, and gels.
In oral care products like toothpastes and mouthwashes, it helps mix active ingredients, such as fluoride, into a stable solution.
Its ability to facilitate the even dispersion of ingredients ensures that these products are effective in treating conditions such as cavities, gum disease, and bad breath.
Disodium lauriminodipropionate’s eco-friendly properties further enhance its appeal in the growing market for sustainable products.
As consumers and manufacturers alike become more environmentally conscious, there is an increasing demand for ingredients that are biodegradable and have a minimal environmental footprint.
Disodium lauriminodipropionate’s biodegradability ensures that it breaks down naturally and does not accumulate in the environment, which is a significant advantage in cleaning and personal care products.
Disodium lauriminodipropionates use in such eco-conscious formulations aligns with the broader trend toward sustainability in the manufacturing of everyday products.
Furthermore, disodium lauriminodipropionate’s role as a solubilizer also extends to its use in the formulation of bio-based and green chemistry products.
In the realm of green chemistry, the compound is helpful in creating formulations that replace petroleum-based surfactants with more natural or renewable alternatives, contributing to the development of products that are both effective and environmentally sustainable.
Lastly, in industrial applications like paint and coating formulations, disodium lauriminodipropionate is used as a dispersing agent.
It helps to evenly disperse pigments, dyes, and other ingredients in the formulation of paints and coatings, ensuring uniform color, texture, and coverage.
This property makes it particularly important in the creation of products that need to maintain consistent appearance and performance over time, such as industrial coatings, automotive paints, and architectural finishes.
Safety Profile Of Disodium lauriminodipropionate:
Although disodium lauriminodipropionate is considered a mild surfactant, it can still cause irritation to the skin, particularly when used in high concentrations or if an individual has sensitive skin.
Prolonged or repeated exposure to high levels of the compound may lead to dryness, redness, or itching, which can be uncomfortable for some individuals.
This risk is higher in products that are left on the skin for extended periods, such as lotions or cleansers.
Direct contact with the eyes may cause mild to moderate irritation.
Symptoms can include redness, stinging, and tearing.
While it is not typically highly irritating, accidental splashes or improper handling should be avoided.
Eye protection should be used when handling high concentrations of disodium lauriminodipropionate, especially in industrial settings or when working with formulations containing high levels of the compound.
Inhalation of the dust or aerosolized particles of disodium lauriminodipropionate, particularly in its concentrated form or when mixed with other chemicals in industrial settings, could cause irritation to the respiratory system.
This may manifest as symptoms such as coughing, wheezing, or shortness of breath.
Proper ventilation and protective equipment such as masks should be used in situations where there is a risk of inhalation exposure.
In rare cases, individuals may experience an allergic reaction to disodium lauriminodipropionate.
Symptoms of an allergic reaction could include rashes, swelling, or hives.
Anyone who experiences signs of an allergic reaction should discontinue use and seek medical advice.
Individuals with known sensitivities to similar surfactants may be at higher risk.
Although disodium lauriminodipropionate is biodegradable, excessive discharge into the environment could still cause localized issues in aquatic systems.
Large quantities entering water bodies might affect the balance of local ecosystems.
Disodium lauriminodipropionate is important to follow proper disposal guidelines to minimize environmental impact.
While disodium lauriminodipropionate is not intended for consumption, accidental ingestion of small amounts in cosmetic or cleaning products is unlikely to cause significant harm.
However, ingestion could lead to gastrointestinal irritation, including symptoms such as nausea, vomiting, or stomach discomfort.
If large amounts are ingested, medical attention should be sought immediately.
While there is limited information suggesting disodium lauriminodipropionate is highly toxic, exposure to high concentrations or prolonged exposure to its active ingredients could pose a risk, especially for individuals with compromised health or pre-existing conditions.
Disodium lauriminodipropionate is important to use the compound within the recommended limits and follow safety guidelines to minimize potential harm.
