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Dl-alpha-tocopherol (synthetic) is used as an antioxidant in oil and fat, fry and unsaturated fatty acid.
Dl-alpha-tocopherol (synthetic) is a synthetic form of vitamin E and is used for its antioxidant properties.
Dl-alpha-tocopherol (synthetic) is found in many personal care products such as skin creams and lotions to promote skin healing and reduce scarring after injuries such as burns.
CAS Number: 10191‑41‑0
EC Number: 233‑466‑0
IUPAC Name: (±)-2,5,7,8‑Tetramethyl‑2‑(4,8,12‑trimethyltridecyl)‑6‑chromanol (synthetic racemic α‑tocopherol)
Molecular Formula: C₂₉H₅₀O₂
Molecular Weight: 430.7 g/mol
SYNONYMS:
dl‑α‑Tocopherol, all‑rac‑α‑tocopherol, synthetic vitamin E, dl‑vitamin E, Dl‑α‑tocopherol, E 307, rac‑alpha‑tocopherol, vitamin E snowe muscle, energy & feritility bayer, tocopherol E mulsin, togasan vitamin e, togasan vitamin E, tocopherol rodisma-med brand E, auxina e hydrosol, vit E, puncto, DL-ALPHA-TOCOPHEROL, Ephanyl, alpha-Tocopherol, DL-, Vitamin E DL-alpha, dl-.alpha.-Tocopherol, UNII-7QWA1RIO01, DL-5,7,8-trimethyltocol, CCRIS 5853, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, EINECS 233-466-0, .Alpha.-tocopherol, DL-, RONOTEC DF 120, IRGANOX E 210, UVINUL 2000AO, BRN 0094012, INS NO.307C, RAC-.ALPHA.-TOCOPHEROL, INS-307C, HSDB 8261, EC 233-466-0, 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, DL-.ALPHA.-TOCOPHEROL [MI], E-307C, 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol, J24.789H, DLalphaTocopherol, allracalphaTocopherol, alphaTocopherol, DL, rac-alpha-tocopherol, DLallracalphaTocopherol, ALPHA-TOCOPHEROL, DL-(II), 6Chromanol, 2,5,7,8tetramethyl2(4,8,12trimethyltridecyl), alpha-tochopherol, dl-|A-tocopherol, TOCOPHEROL, Tocopheroxy radical, DL-alpha tocopherol, all-rac-alpha-Tocopherol, a-Tocopherol, (+/-)-alpha-Tocopherol, 113085-06-6, 1406-18-4, CHEMBL49563, dl-?-Tocopherol, DL-alpha-Tocopherol (Vitamin E), Vita E, .alpha.-Tocopherol, all-rac-alpha-Tocopherol (Vitamin E), Evitaminum, Waynecomycin, Almefrol, Emipherol, Etamican, Vitayonon, Ilitia, Vitaplex E, Spavit E, ido-E, Endo E, Antisterility vitamin, RRR-alpha-tocopherol, Tocopheroxyl radical, DL-Tocopherol, NSC-20812, DL-ALPHA-TOCOPHEROL(307C), Pharmakon1600-00310039, DL-ALPHA TOCOPHEROL [WHO-DD], (2S, 4'R, 8'S)-?-Tocopherol, AKOS015960364, ALL-RAC-ALPHA-TOCOPHEROL [FCC], DB14476, (+/-)-alpha-Tocopherol, synthetic, >=96% (HPLC), alpha-Tocopherol, British Pharmacopoeia (BP) Reference Standard, Alpha Tocopherol, European Pharmacopoeia (EP) Reference Standard, Alpha Tocopherol, United States Pharmacopeia (USP) Reference Standard, Alpha Tocopherol, Pharmaceutical Secondary Standard; Certified Reference Material
Dl-alpha-tocopherol (synthetic) is not clear if individuals allergic to dl alpha tocopherol will cross react with related derivatives.
Dl-alpha-tocopherol (synthetic) may be stored for 24 months from the date of manufacture in the unopened original container and at room temperature.
Dl-alpha-tocopherol (synthetic) has been reported, Sida acuta, and other organisms with data available.
Dl-alpha-tocopherol (synthetic) is a synthetic form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.
Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acids), Dl-alpha-tocopherol (synthetic) is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production.
Dl-alpha-tocopherol (synthetic)also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription. (NCI04)
Dl-alpha-tocopherol (synthetic) is a generic descriptor for all tocopherols and tocotrienols that exhibit alpha-tocopherol activity.
By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of isoprenoids.
The effect of light spot whitening, preventing skin aging, regulating endocrine, preventing three highs and thrombosis.
Therefore, Dl-alpha-tocopherol (synthetic) is widely used in food, nutrition health products cosmetics, and other fields.
USES and APPLICATIONS of DL-ALPHA-TOCOPHEROL (SYNTHETIC):
Dl-alpha-tocopherol (synthetic) is used as an antioxidant in oil and fat, fry and unsaturated fatty acid.
Dl-alpha-tocopherol (synthetic) is safe for the intended use.
Dl-alpha-tocopherol (synthetic) is a synthetic form of vitamin E and is used for its antioxidant properties.
Dl-alpha-tocopherol (synthetic) is found in many personal care products such as skin creams and lotions to promote skin healing and reduce scarring after injuries such as burns.
Food Additive (E 307): Dl-alpha-tocopherol (synthetic) prevents rancidity in oils, fats, margarine, bakery, snacks, dressings, infant formula, and animal feed
Dietary Supplement: Synthetic vitamin E provides ~73.5% potency compared to natural form; typical doses ≤ 1,100 IU/day deemed safe
Cosmetics & Skin Care: Dl-alpha-tocopherol (synthetic) is used as antioxidant and skin-conditioning agent in creams, lotions, serums; supports skin healing, reduces oxidative stress
Pharmaceuticals: Dl-alpha-tocopherol (synthetic) is incorporated in formulations for antioxidant and cytoprotective effects; found in vitamin supplements and fortified foods
WHERE IS DL-ALPHA-TOCOPHEROL (SYNTHETIC) FOUND?
Dl-alpha-tocopherol (synthetic) is a synthetic form of vitamin E and is used for its antioxidant properties.
Dl-alpha-tocopherol (synthetic) is found in many personal care products such as skin creams and lotions to promote skin healing and reduce scarring after injuries such as burns.
Dl-alpha-tocopherol (synthetic) is not clear if individuals allergic to dl alpha tocopherol will cross react with related derivatives.
WHAT ARE SOME PRODUCTS THAT MAY CONTAIN DL-ALPHA-TOCOPHEROL (SYNTHETIC)?
Antifungal Products
• Athlete’s foot
• Jock itch
Baby and Body Powder
Baby Wipes
Cold Sore Products
Cosmetics
• Blush
• Eye liner
• Foundation
• Mascara
• Nail polish
• Pressed powder
Deodorants
Gum and Mints
Hair Care Products
• Conditioner
• Hair dye
• Hairspray
• Hot oil treatments
• Leave-in conditioner
• Mousse
• Sculpting cream
• Shampoo
Lip Balms/Lipsticks
Lotions and Moisturizers
Shaving Creams and Gels
Skin Care Products
• Antioxidant creams
• Anti-itch creams/gels
• Scar treatment
Soaps and Cleansers
• Bar soap
• Body wash
• Cleansing cloths
Sunscreens
Vitamin E Supplements
✔️ FUNCTIONAL BENEFITS OF DL-ALPHA-TOCOPHEROL (SYNTHETIC):
*Potent Lipid Antioxidant:
Dl-alpha-tocopherol (synthetic) stabilizes oils, fats, cell membranes, LDL cholesterol
*Nutritional Value:
Essential vitamin supporting immune function, cardiovascular and neurological health
*Shelf-life Extender:
Dl-alpha-tocopherol (synthetic) protects against oxidative spoilage in food and cosmetics
CHEMICAL CLASS AND MECHANISM OF DL-ALPHA-TOCOPHEROL (SYNTHETIC):
Dl-alpha-tocopherol (synthetic) is a fat-soluble antioxidant—part of the tocopherol family (vitamin E)—with a chromanol ring donating hydrogen to neutralize free radicals, protecting lipids and membranes from oxidative damage
PHYSICAL and CHEMICAL PROPERTIES of DL-ALPHA-TOCOPHEROL (SYNTHETIC):
Appearance: Pale yellow to yellowish-brown viscous oil
Odor: Nearly odorless or light ester-like odor
Melting Point: ~2–4 °C
Boiling Point: 200–220 °C at 0.1 mmHg
Density: ~0.950 g/mL @ 20 °C
Vapor Pressure: < 1 hPa @ 20 °C
Solubility: Insoluble in water; soluble in fats/oils, alcohol, ether, acetone, chlorinated solvents
Log P: ~+10 to +12 (highly lipophilic)
Stability: Light- and air-sensitive; degrades under oxidation; flash point ~240 °C
CAS Number: 10191-41-0
EC Number: 233-466-0
IUPAC Name: (±)-2,5,7,8‑Tetramethyl‑2‑(4,8,12‑trimethyltridecyl)‑6‑chromanol (synthetic racemic α‑tocopherol)
Molecular Formula & Weight: C₂₉H₅₀O₂; MW ~430.7 g/mol
Molecular Weight: 430.7 g/mol
XLogP3-AA: 10.7
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 12
Exact Mass: 430.381080833 Da
Monoisotopic Mass: 430.381080833 Da
Topological Polar Surface Area: 29.5 Ų
Heavy Atom Count: 31
Formal Charge: 0
Complexity: 503
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 3
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Physical State: Viscous liquid
Color: Light yellow
Odor: Odorless
Melting Point: 2.5 - 3.5 °C
Initial Boiling Point and Range: 208 - 210 °C at 0.0266 hPa
Decomposition Temperature: > 300 °C
Viscosity, Dynamic: 4.200 mPa·s at 20 °C
Water Solubility: 0.00001 g/L at 20 °C (OECD Test Guideline 105)
Partition Coefficient (log Pow): > 6 (potential bioaccumulation)
Vapor Pressure: 13 hPa at 155 °C
Density: 0.95 g/mL at 20 °C
Relative Density: 0.95 at 25 °C
Other: Flammability data, explosive properties, oxidizing properties, pH, viscosity (kinematic),
particle characteristics, and safety info — no data available.
FIRST AID MEASURES of DL-ALPHA-TOCOPHEROL (SYNTHETIC):
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of DL-ALPHA-TOCOPHEROL (SYNTHETIC):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of DL-ALPHA-TOCOPHEROL (SYNTHETIC):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of DL-ALPHA-TOCOPHEROL (SYNTHETIC):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of DL-ALPHA-TOCOPHEROL (SYNTHETIC):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of DL-ALPHA-TOCOPHEROL (SYNTHETIC):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available
