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DMDM HYDANTOIN

CAS Number   :   6440-58-0 
EC Number    :   229-222-8
ECHA InfoCard    : 100.026.566 
PubChem CID    : 22947
ChemSpider    : 21482 
Chemical formula   :  C7H12N2O4
Molar mass       :  188.18 g/mol

DMDM hydantoin is an antimicrobial formaldehyde releaser preservative with the trade name Glydant. 
DMDM hydantoin is an organic compound belonging to a class of compounds known as hydantoins. 
DMDM hydantoin is used in the cosmetics industry and found in products like shampoos, hair conditioners, hair gels, and skin care products.
DMDM hydantoin slowly releases formaldehyde and works as a preservative by making the environment less favorable to microorganisms.

Safety of DMDM hydantoin
A patch test study found that "an increase in the use of DMDM hydantoin in cosmetic products will also inevitably increase the risk of cosmetic dermatitis in consumers allergic to formaldehyde."

The safety of formaldehyde is a topic of ongoing concern, given the prevalence of formaldehyde and formaldehyde releasers in industrial uses. 
Formaldehyde is considered "an important metabolic product in plants and animals (including humans), where it occurs in low but measurable concentrations." However, long-term exposure to formaldehyde (particularly routine inhalation of its fumes) is thought to cause irritation of the eyes and mucous membranes,headaches, shortness of breath, and aggravation of asthma symptoms.
DMDM hydantoin was declared a "toxic product" by the 1999 Canadian Environmental Protection Act, and the US National Toxicology Program officially classed formaldehyde as "known to be a human carcinogen in June 2011.
In the EU, the maximum allowed concentration of formaldehyde in finished products is 0.2%, and any product that exceeds 0.05% has to include a warning that the product contains formaldehyde.

Use and Manufacturing of DMDM hydantoin
Used as a biocide in cosmetics with 0.6% the maximum allowable concentration in the EU; [Kanerva, p. 398, 407] Used as an antimicrobial pesticide in cleaning products, adhesives, air fresheners, caulks, hydraulic fluids, inks, metal working cutting fluids, paints, stains, coatings, paper and paperboard coatings, polishes, synthetic polymers, sealants, starch solutions, resin emulsions, textiles, and wax

DMDM Hydantoin is a cosmetic preservative. 
DMDM Hydantoin is described as being a broad-spectrum antimicrobial agent, effective against fungi, yeast, and gram-positive and gram-negative bacteria.

DMDM Hydantoin is a preservative which is used in cosmetic products at concentrations up to 1%. 
This ingredient is a formaldehyde donor containing up to 2% of the free aldehyde in equilibrium with the hydantoin.

Preserves and aids in the control of bacteria and fungi in liquid detergents, fabric softeners, household cleaning products, soft soaps, water-based paints for household and industrial use, room deodorizers and air fresheners, water-based surfactants, polymer emulsions, protective or decorative coatings, water-based gels for household and industrial products, textiles, water-based adhesives, sealants and caulks, latex for paper coatings, and water-based inks.

Industry Uses of DMDM Hydantoin
-Intermediates
-Preservative
-Processing aids, not otherwise listed

Consumer Uses of DMDM Hydantoin 
-Building/construction materials not covered elsewhere
-Cleaning and furnishing care products

Household Products of DMDM Hydantoin 
Household & Commercial/Institutional Products
Information on 794 consumer products that contain DMDM hydantoin in the following categories is provided:
-Auto Products
-Commercial / Institutional
-Home Maintenance
-Inside the Home
-Personal Care
-Pet Care

General Manufacturing Information    
Industry Processing Sectors
-All other basic organic chemical manufacturing
-All other chemical product and preparation manufacturing
-Construction

Application of DMDM Hydantoin : 
DMDM Hydantoin is a preservative and antimicrobial agent found in a wide range of cosmetics and skin-care and hair-care products. 
DMDM Hydantoin's considered a “formaldehyde donor.” That means it releases a small amount of formaldehyde over time to help keep products fresh and free from contaminants. 
Formaldehyde-releasing preservatives like DMDM hydantoin help keep beauty products from spoiling. 
While formaldehyde-releasing ingredients can be dangerous in high levels, these chemicals are found naturally in safe, small amounts in many foods. 
DMDM Hydantoin helps your personal-care items stay fresh for long periods. 
The chemical stops or slows down the growth of potentially harmful fungi, yeast, and bacteria.

DMDM hydantoin is a preservative and antimicrobial agent found in a wide range of cosmetics and skin-care and hair-care products. 
It's considered a “formaldehyde donor.” That means it releases a small amount of formaldehyde over time to help keep products fresh and free from contaminants.

DMDM hydantoin in:
-Makeups
-Makeup removers
-Shampoos
-Conditioners
-Hair styling products
-Moisturizers
-Liquid hand soaps
-Facial cleansers
-Exfoliants or scrubs

Benefits of DMDM Hydantoin
DMDM hydantoin helps your personal-care items stay fresh for long periods. 
The chemical stops or slows down the growth of potentially harmful fungi, yeast, and bacteria.

DMDM hydantoin is an antimicrobial formaldehyde releaser preservative. 
People exposed to such formaldehyde-releasing ingredients may develop a formaldehyde allergy or an allergy to the ingredient itself and its decomposition products. 
In the U.S., approximately 20% of cosmetics and personal care products contain a formaldehyde-releaser and the frequency of contact allergy to these ingredients is much higher among Americans compared to studies in Europe.

DMDM hydantoin is a crystal-like, odorless chemical often used in cosmetics as a preservative. 
Several products contain the chemical, from makeup and moisturizers to shampoos and conditioners.
DMDM hydantoin is a type of formaldehyde-releaser.
A formaldehyde-releaser is a chemical often found in personal care products. 
DMDM hydantoin releases small amounts of formaldehyde over time to preserve the products.

Uses and benefits  of DMDM hydantoin:
-shampoos
-conditioners
-makeup
-makeup removers
-liquid hand soaps
-styling products
-facial cleansers
-moisturizers
-sunscreen

DMDM hydantoin has antimicrobial properties, which means it can help kill small organisms and preserve the product’s freshness.
Antimicrobial chemicals such as DMDM hydantoin can help prevent the growth of potentially harmful:

-bacteria
-fungus
-yeast

DMDM Hydantoin is a formaldehyde donor and is used as a preservative in cosmetic products shampoos, skin-care products, hair conditioners, makeup and hair rinses. 
DMDM Hydantoin is also used in herbicides, polymers, color photography, latex paints, floor waxes, cutting oils, adhesives, copying paper and inks. 
Further research may identify additional product or industrial usages of this chemical.

DMDM Hydantoin releases antimicrobial formaldehyde, making it one of the most efficient artificial preservatives in the world. 
It is an organic compound that finds its place in the hydantoins class of compounds. 
The compound finds extensive use in the cosmetics industry as an active preservative for products like:

Skin care composition
-Shampoos
-Hair gels
-Hair conditioners

Being an effective preservative, DMDM Hydantoin is used in the concentrated form of 1%. 
As mentioned earlier, DMDM Hydantoin is a donor of formaldehyde making it capable of creating a not-so-favourable ambience within the cosmetic product for microorganisms to thrive.

APPLICATIONS AND BENEFITS OF DMDM HYDANTOIN:
The compound is a favourite among mass producers of cosmetics and skin care products all over the globe. 
DMDM Hydantoin has shown efficiency when it comes to slowing down the spoilage rate of products and improves their shelf life.
The compound is one of the best antimicrobial agents that helps prevent the growth of yeast, fungi and harmful dermatological bacteria that if left unchecked can result in skin rashes, and related illnesses in users.

Benefits of DMDM Hydantoin
-Promotes blood circulation in the scalp
-Revitalizes hair follicles
-Stimulates hair growth
-Increases hair thickness
-Eliminates dry scalp combating problems including dandruff and dry hair
-Protects collagen from degrading
-Prolongs duration of hair transplants

FIRST AID MEASURES of DMDM Hydantoin
GENERAL INFORMATION: Not applicable.

INHALATION: 
Ensure supply of fresh air. 
In the event of symptoms refer for medical treatment

SKIN CONTACT: 
Wash off immediately with soap & water. 
Consult a doctor if skin irritation persists.

EYE CONTACT: 
Rinse thoroughly with plenty of water and seek medical advice.

INGESTION: Rinse out mouth and give plenty of water to drink. 
Seek medical advice immediately.


Substance identity

EC / List no.: 229-222-8
CAS no.: 6440-58-0
Mol. formula: C7H12N2O4

Hazard classification & labelling of DMDM hydantoin
Warning! According to the classification provided by companies to ECHA in REACH registrations this substance is harmful if swallowed.

About DMDM hydantoin
DMDM hydantoin is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
DMDM hydantoin is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Biocidal Uses of DMDM hydantoin
DMDM hydantoin is being reviewed for use as a biocide in the EEA and/or Switzerland, for: product preservation, preservation for working / cutting fluids.

Consumer Uses of DMDM hydantoin
DMDM hydantoin is used in the following products: cosmetics and personal care products, perfumes and fragrances, pharmaceuticals, washing & cleaning products, finger paints and inks and toners.
Other release to the environment of DMDM hydantoin is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

Article service life of DMDM hydantoin
ECHA has no public registered data on the routes by which DMDM hydantoin is most likely to be released to the environment. 
ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

Widespread uses by professional workers of DMDM hydantoin
DMDM hydantoin is used in the following products: cosmetics and personal care products, perfumes and fragrances, pharmaceuticals and washing & cleaning products.
DMDM hydantoin is used in the following areas: health services.
Other release to the environment of DMDM hydantoin is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Formulation or re-packing of DMDM hydantoin
DMDM hydantoin is used in the following products: cosmetics and personal care products, pH regulators and water treatment products and laboratory chemicals.
Release to the environment of DMDM hydantoin can occur from industrial use: formulation of mixtures and formulation in materials.

Uses at industrial sites of DMDM hydantoin
DMDM hydantoin is used in the following products: pH regulators and water treatment products and laboratory chemicals.
DMDM hydantoin is used in the following areas: health services and scientific research and development.
DMDM hydantoin is used for the manufacture of: chemicals.
Release to the environment of DMDM hydantoin can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.

Manufacture of DMDM hydantoin
Release to the environment of DMDM hydantoin can occur from industrial use: manufacturing of the substance.


Synonyms:
1,3-Bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione
1,3-Bis(hydroxymethyl)-5,5-dimethylhydantoin
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione (DMDMH)
1,3-Di(hydroxymethyl)-5,5-dimethylhydantoin
1,3-Dimethylol-5,5-dimethylhydantoin
2,4-Imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
Dantoin dmdmh 55
Dantoin-DMDMH
Dimethylol-5,5-dimethylhydantoin
DMDM Hydantoin
Dmdmh
Dmdmh 55
Glycoserve-DMDMH
Glydant
Hydantoin, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
1,3-bis(hidroksimetil)-5,5-dimetilimidazolidin-2,4-dion (DMDMH) (sl)
1,3-bis(hidroksimetil)-5,5-dimetilimidazolidin-2,4-dionas (DMDMH) (lt)
1,3-bis(Hidroksimetil)-5,5-dimetilimidazolidīn-2,4-dions (DMDMH) (lv)
1,3-bis(hidroksimetil)-5,5-dimetillimidazolidin-2,4-dion (DMDMH) (hr)
1,3-bis(hidroximetil)-5,5-dimetilimidazolidin-2,4-dionă (DMDMH) (ro)
1,3-bis(Hidroximetil)-5,5-dimetilimidazolidina-2,4-diona (DMDMH) (es)
1,3-bis(hidroximetil)-5,5-dimetilimidazolidina-2,4-diona (DMDMH) (pt)
1,3-bis(hydroksimetyyli)-5,5-dimetyyli-imidatsolidiini-2,4-dioni (DMDMH) (fi)
1,3-bis(hydroksymetylo)-5,5-dimetyloimidazolidino-2,4-dion (DMDMH) (pl)
1,3-bis(hydroximetyl)-5,5-dimetylimidazolidin-2,4-dion (DMDMH) (sv)
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidin-2,4-dion (DMDMH) (cs)
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidin-2,4-dion (DMDMH) (da)
1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidin-2,4-dion (DMDMH) (de)
1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dion (DMDMH) (nl)
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione (DMDMH) (no)
1,3-bis(hydroxymetyl)-5,5-dimetylimidazolidín-2,4-dión (DMDMH) (sk)
1,3-bis(hydroxyméthyl)-5,5-diméthylimidazolidine-2,4-dione (DMDMH) (fr)
1,3-bis(hüdroksümetüül)-5,5-dimetüülimidasolidiin-2,4-dioon (DMDMH) (et)
1,3-bis(idrossimetil)-5,5-dimetilimidazolidin-2,4-dione (DMDMH) (it)
1,3-Bis(idrossimetil)-5,5-dimetilimidażolidina-2,4-dion (DMDMH) (mt)
1,3-bisz(hidroximetil)-5,5-dimetil-imidazolidin-2,4-dion (DMDMH) (hu)
1,3-δις(υδροξυμεθυλο)-5,5-διμεθυλιμιδαζολιδινο-2,4-διόνη (DMDMH) (el)
5,5-диметил-1,3-бис(хидроксиметил)имидазолидин-2,4-дион (DMDMH) (bg)
2,4-Imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
1,3- Di(hydroxymethyl) -5,5-dimethylhydantoin
1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione (DMDMH)
1,3-bis)hydroxymethyl)-5.5-dimethylmidazolidine-2.4-dione
2,4-Imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
DMDM Hydantoin
DMDMH
oxybenzone
Glydant XL-1000
6440-58-0
6440-58-0
1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
DMDM Hydantoin
Dimethyloldimethyl hydantoin
Dmdmh
Glydant
1,3-Bis(hydroxymethyl)-5,5-dimethylhydantoin
1,3-Dimethylol-5,5-dimethylhydantoin
Dimethylol-5,5-dimethylhydantoin
dimethyloldimethylhydantoin
2,4-Imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
1,3-Bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione
BYR0546TOW
1,3-DIHYDROXYMETHYL-5,5-DIMETHYLHYDANTOIN
MFCD00467199
1,3-DIMETHYLOL-5,5-DIMETHYL-HYDANTOIN
Dantoin-DMDMH
Glycoserve-DMDMH
Dantoin dmdmh 55
Dmdmh 55
Caswell No. 273AB
EINECS 229-222-8
UNII-BYR0546TOW
EPA Pesticide Chemical Code 115501
BRN 0882348
1,3-Di(hydroxymethyl)-5,5-dimethylhydantoin
HSDB 7488
1,3-Dihydroxylmethyl-5,5-dimethylhydantoin
EC 229-222-8
dimethylol dimethyl hydantoin
DMDM HYDANTOIN [II]
DSSTox_CID_15217
DSSTox_GSID_35217
SCHEMBL69185
Hydantoin, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
DMDM HYDANTOIN [INCI]
DMDM HYDANTION [VANDF]
DMDM HYDANTOIN [VANDF]
DTXSID8035217
ZINC2033948
Tox21_303842
AKOS006345746
CS-W021276
NCGC00356947-01
AS-10924
SY101650
CAS-6440-58-0
FT-0606699
H11751
440B580
A834743
Q5205613
W-104844
1,3-DIMETHYLOL-5,5-DIMETHYLHYDANTOIN [HSDB]
1,3-Bis (hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
1,3 BIS(HYDROXYMETHYL)-5,5- DIMETHYLHYDANTOINDIMETHYLHYDANTOIN
5-ethyl-1,3-dihydroxy-5-methyl-imidazolidine-2,4-dione;1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
1,3-bis(hydroxymethyl)-5,5-dimethyl-1,3-diazolidine-2,4-dione
1,3-Bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidindion [German] [ACD/IUPAC Name]
1,3-Bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione [ACD/IUPAC Name]
1,3-Bis(hydroxyméthyl)-5,5-diméthyl-2,4-imidazolidinedione [French] [ACD/IUPAC Name]
1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
1,3-dimethylol-5,5-dimethylhydantoin
1,3-DIMETHYLOL-5,5-DIMETHYL-HYDANTOIN
2,4-Imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl- [ACD/Index Name]
229-222-8 [EINECS]
6440-58-0 [RN]
BYR0546TOW
DMDM hydantoin [Wiki]
Glydant
Hydantoin, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
1,3-Bis(hydroxymethyl)-4,4-dimethyl-2,5-dioxoimidazolidine
1,3-bis(hydroxymethyl)-5,5-dimethyl-imidazolidine-2,4-dione
1,3-Di(hydroxymethyl)-5,5-dimethylhydantoin
1,3-Dihydroxylmethyl-5,5-dimethylhydantoin
1,3-Dihydroxymethyl-5,5-dimethylhydantoin
1,3-Dimethylol-5,5-dimethylhydantion
1.3-Methylol-5,5-dimethylhydantoin
5,5-dimethyl-1,3-dimethylol-hydantoin
5-ethyl-1,3-dihydroxy-5-methylimidazolidine-2,4-dione
Dantoin dmdmh 55
Dantoin-DMDMH
Dimethylol Dimethyl Hydantoin
DIMETHYLOL-5,5-DIMETHYLHYDANTOIN
Dimethyloldimethyl hydantoin
dimethyloldimethylhydantoin
DMDM Hydantoin|DMDMH
EINECS 229-222-8
Glycoserve-DMDMH
MFCD00467199 [MDL number]
N,N-dimethyl((R)-piperidin-3-yl)methanamine
UNII:BYR0546TOW
UNII-BYR0546TOW

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