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CAS: 6440-58-0
DMDM Hydantoin is a preservative, which is used in cosmetic products at concentrations up to 1 %. This ingredient is a formaldehyde donor containing up to 2% of the free aldehyde in equilibrium with the hydantoin.
Use of DMDM Hydantoin at its current concentration of use in cosmetic products would not expose the consumer to levels of formaldehyde above the limit previously considered as acceptable in cosmetic products. Based on the available data, it is concluded that DMDM Hydantoin is safe as a cosmetic ingredient in the present practices of use.
SYNONYMS:
1,3-dimethylol-5,5-dimethyl hydantoin, Dimethylol-5,5-dimethylhydantoin, Bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione, Glydant, Bis(hydroxymethyl)-5,5-dimethylhydantoin, Glydant Plus, Dimethyloldimethyl hydantoin, Hydantoin, 1,3-bis(hydroxymethyl)-5,5-dimethyl-, DMDMH, Imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl-, Dantion DMDMH 55, Mackgard DM, Dantoguard, Nipaguard DMDMH; 1,3-DIHYDROXYLMETHYL-5,5-DIMETHYLHYDANTOIN; 1,3-dimethylol-5,5-dimethyl hydantoin; 1,3-Bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione; 1,3-BIS(HYDROXYMETHYL)-5,5-DIMETHYLHYDANTOIN; bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione; Bis(hydroxymet; 1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione; DMDM Hydantoin; 1,3-Bis(hydroxymethyl)-5,5-dimethylhydantoin; 2,4-Imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl-dimethyloldimethylhydantoin; UNII-BYR0546TOW; Glydant; 1,3-Dihydroxylmethyl-5,5-dimethylhydantoin; Dantoin-DMDMH; Glycoserve-DMDMH; Dantoin dmdmh 55; Dmdmh 55; Caswell No. 273AB; Dimethylol-5,5; dimethylhydantoin; EINECS 229-222-8; EPA Pesticide Chemical Code 115501; BRN 0882348; 1,3-bis(hydroxymethyl)-5,5-dimethyl-1,3-diazolidine-2,4-dione; 1,3-Bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione; 1,3-Di(hydroxymethyl)-5,5-dimethylhydantoin; HSDB 7488; dimethylol dimethyl; hydantoin; DSSTox_CID_15217; DSSTox_GSID_35217; SCHEMBL69185; 1,3-DIHYDROXYMETHYL-5,5; DIMETHYLHYDANTOIN; Hydantoin, 1,3-bis(hydroxymethyl)-5,5-dimethyl-; DTXSID8035217; ZINC2033948; Tox21_303842; KM0857; SBB055875; AKOS006345746; CS-W021276; FT-0606699; ST50950036; 1,3-DIMETHYLOL-5,5-DIMETHYL-HYDANTOIN; 440B580; Q5205613; W-104844;
1,3-Bis (hydroxymethyl) -5,5-dimethylimidazolidine-2,4-dione
Chemical Name: Dimethyl dimethylol hydantoin.
Definition of: It is a powerful protector. It is a highly water soluble preservative that can be applied to a wide range of personal care and detergent based products.
Benefits:
- DMDM is a 55% solution of hydratoin in water. It is particularly effective in detergent-based formulations that may have inseparable microbial activity but are susceptible to developing certain types of microorganisms.
- It has broad spectrum activity against gram negative, gram positive, yeasts and molds.
- pH: superior effect in the range of 3-8,
- It is not irritating to eyes, skin and mucous membranes in normal use concentrations (0.15-0.4%).
- It does not lose its activity in the presence of the most known components of personal care products and nonionic surfactants.
- It is very soluble in water and easily included in products.
- It has an excellent toxicity profile.
Applications:
DMDMH; It can be used in a wide variety of personal care products, including shampoos, conditioners, hair conditioning creams, lotions, baby products, eyeliner, mascaras and almost all water-based cosmetics and toiletries. DMDMH is an ideal preservative for bulk surfactants. Typically used in concentrations of 0.15-0.4%. It is inexpensive, water soluble, has low oil solubility, broad spectrum activity, low concentrations active, non-volatile, good heat stability. As a disadvantage, it is a formaldehyde donor.
Use of:
It is a 55% solution of DMDMH in water and can be directly added to aqueous solutions. In hot processes (such as emulsification), it is recommended to add DMDMH preferably at a temperature below 60oC during the cooling step.
DMDM hydantoin is an antimicrobial formaldehyde releaser preservative with the trade name Glydant. DMDM hydantoin is an organic compound belonging to a class of compounds known as hydantoins. It is used in the cosmetics industry and found in products like shampoos, hair conditioners, hair gels, Rite Aid Liquid Lubricant, and skin care products.
DMDM hydantoin slowly releases formaldehyde and works as a preservative by making the environment less favorable to the microorganisms.
DMDM hydantoin is an odorless white, crystalline substance that works as an antimicrobial agent and preservative in cosmetics and personal care products.
Cosmetics and personal care products
DMDM hydantoin is a preservative in cosmetics and personal care products. It works by slowing and preventing spoilage in products such as shampoos and hair conditioners, and in skin care products like moisturizers and makeup foundations.
DMDM hydantoin is also an antimicrobial agent used in cosmetics and personal care products. As an antimicrobial, it can help prevent the growth of fungi, yeast and harmful bacteria that can make people sick or give them rashes, for example
DMDM Hydantoin is a white, crystalline solid. In cosmetics and personal care products, DMDM Hydantoin is used in the formulation of shampoos, hair conditioners, skin care products, moisturizers, bath products, and makeup bases and foundations.
DMDM Hydantoin is a formaldehyde-donor preservative, that prevents or retards microbial growth, thereby protecting cosmetics and personal care products from spoilage.
1,3-Dimethyol-5,5-dimethyl hydantoin (DMDM hydantoin) is an odorless powder or solid. It is slightly volatile and very soluble in water. It is a member of a group of chemicals called hydroxymethyl dimethyl hydantoins, which are formaldehyde releasers. The hydroxymethyl dimethyl hydantoin group also includes hydroxymethyl-5,5-dimethyl hydantoin (MDM hydantoin). USE: DMDM hydantoin and MDM hydantoin are used as antimicrobial agents and preservatives in cosmetics, adhesives, air freshners, caulks, cleansers, fabric softeners, hydraulic fluids, inks, liquid detergents, metalworking cutting fluids, paints, powdered detergents, sealants, carpet shampoos, soap, stains and coatings, paper/paperboard coatings, starch solutions, textiles, and wax.
Description: Organic compound belonging to a class of compounds known as hydantoins. Very effective broad-spectrum preservative. Clear liquid. pH (as is): 6.5-7.5. Active content 55.0 - 58.0%. Easily soluble in water.
INCI Name: DMDM hydantoin
Benefits:
• Effective broad-spectrum preservation against gram-positive and gram-negative bacteria, yeast, and mold
• For its high water solubility, it is particularly suggested for aqueous formulations and emulsions
• Extends shelf life of personal care products typically to 6-18 months
• Compatible with most cosmetic ingredients
• Product is non-irritating and non-sensitizing
• Environmentally friendly as it will not build up in aquatic organisms and will be broken down by microorganisms in soil.
Use: Recommended use level of 0.1-0.6% (approved for use up to 1% in USA and up to 0.6% in Europe). Performs well at pH levels up to 10 (ideal pH 4-10). Can be added directly to the formulation during pre- or post-emulsification at or below 60°C/140°F. For external use only.
Applications: All kinds of skin & hair care products, wipes, sun care products, & makeup products.
bio-based
Creams, lotions, gels,
Decorative Cosmetics/ Make Up
Hair Care (Shampoos, Conditioners, Styling)
Non-irritant
Perfumes and fragnances
Protections
Skin Cae (Facial care, Facial cleansing, Body care, Baby care)
Sun Care (Sun protection, After Sun and Self-tunning)
Wash-off/rinse
Toiletries (Shower and Bath, Oral Care)
DMDM Hydantoin is formaldehyde-donor preservative , that prevents or retards microbial growth, thereby protecting cosmetics and personal care products; body wash and sprays, moisturisers, creams, toners, lotions, cleansers, hair care, pet care.
“Formaldehyde is a naturally occurring substance made of carbon, hydrogen and oxygen. Humans produce about 1.5 ounces of formaldehyde a day as a normal part of our metabolism. Inhaled formaldehyde is rapidly metabolized and ultimately converted to carbon dioxide and exhaled. Formaldehyde does not accumulate in the body.”
The Cosmetic Ingredient Review (CIR), an independent expert scientific panel established by the Personal Care Products Council, also has evaluated the scientific data and concluded that DMDM hydantoin is safe as a cosmetic ingredient at current levels of use – 0.074 percent, or less. In 2005, the CIR Expert Panel considered available new data on DMDM hydantoin and reaffirmed its safety conclusion. The Cosmetics Directive of the European Union also has approved DMDM hydantoin as a preservative in cosmetics and personal care products at a maximum concentration of 0.6 percent"
Consumer Uses:
Building/construction materials not covered elsewhere
Cleaning and furnishing care products
Industry Uses:
Intermediates
Preservative
Processing aids
Preservatives:
The term “preservatives” refers to the functional name for a wide variety of compounds that help slow or prevent bacterial growth in a wide range of products, including foods, medicines, and personal care products. These compounds can be natural or synthetic. Preservatives play important roles in many products people use every day – for example, by helping prevent the growth of harmful microorganisms and protect products from spoilage or contamination.
Preservatives in Food
Preservatives are added to food to fight spoilage caused by bacteria, molds, fungus, and yeast. Preservatives can keep food fresher for longer periods of time, extending its shelf life. Food preservatives also are used to slow or prevent changes in color, flavor or texture and delay rancidity.
Preservatives in Medicine and Pharmaceuticals
Preservatives are used commonly in medicines such as acetaminophen, insulin and cough syrup to help prevent microbial contamination. Simply, preservatives help prevent the growth of microorganisms, particularly bacteria and fungi, which may cause disease or infection.
Preservatives in Cosmetics and Personal Care Products
Preservatives in cosmetics and personal care products help prevent contamination and the growth of harmful bacteria in products ranging from sunscreens, lotions and shampoos to cleansers, toothpaste and makeup.
Antimicrobial preservatives in cosmetics and personal care products help prevent the growth of molds, yeasts and bacteria, guarding against contamination that can cause irritation or infections. Antioxidant preservatives also can help keep personal care products from spoiling by suppressing reactions that can occur when certain ingredients in a cosmetic or personal care product combine with oxygen in the presence of light, heat and some metals.
Preservatives in Wood
Wood treated with preservatives can be used to build telephone poles, road signs and marine pilings as well as decks, play structures and raised garden beds.
About this substance
This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Biocidal Uses
This substance is being reviewed for use as a biocide in the EEA and/or Switzerland, for: product preservation, preservation for working / cutting fluids.
Consumer Uses
This substance is used in the following products: cosmetics and personal care products, perfumes and fragrances, pharmaceuticals, washing & cleaning products, finger paints and inks and toners.
Other release to the environment of this substance is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Dimethylol dimethyl hydantoin (DMDM hydantoin), is a common preservative ingredient found in cosmetics production, construction materials, and household products. The chemical compound is typically added to products in minute quantities as an antimicrobial agent. Certain consumer advocates fear that when combined with other chemicals, the substance may cause cancer. Some individuals may develop skin irritations while using topical products containing this chemical formulation.
Other names for the compound include 1,2-demithylol-5,5 dimethyl hydantoin and dimethyl-2,4-imidazolidinedione. DMDM hydantoin is generally an organic compound that prevents bacterial, fungal, and viral development. By regulation standards, products usually contain only 0.1% to 0.6% of the substance. Different physical forms of the compound include a colorless liquid, a crystalline powder, or white to grey colored flakes. The compound consists of dimethyl hydantoin and formaldehyde.
Common cosmetic products containing DMDM hydantoin include hair conditioners, gels, and shampoos. Manufacturers also frequently use the substance in cream and lotion-type skin care products. Many industries incorporate the compound for its fungal and mold resistant properties. The substance might accompany ingredients used for adhesives, inks, and latex paints. Herbicides, paper, and photography supplies commonly contain this ingredient.
In addition to DMDM hydantoin, some cosmetic compounds may contain dimethicone, methylparaben, and formaldehyde. Dimethicone is an oily emollient used for skin softening. Methylparaben and formaldehyde are also antimicrobial preservatives. Formaldehyde, or CH2O, is a known carcinogen. Other names for the chemical are formalin, methyl aldehyde, morbicid acid, and oxymethylene.
This invention is for the use of DMDM Hydantoin as a pharmaceutical compound for the treatment of malconditions of mammalian and human skin and membranes. In particular, DMDM Hydantoin may be used to treat dermatological conditions such as acne, burns, and lacerations. DMDM Hydantoin may also be used as an aqueous spray, mouthwash and may be used to treat eye and ear infections as well as to treat mastitis in cattle.
IUPAC Names:
1,3- Di(hydroxymethyl) -5,5-dimethylhydantoin
C&L Inventory
1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
C&L Inventory, Registration dossier, Other
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
C&L Inventory, Registration dossier, Other
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione (DMDMH)
Registration dossier
1,3-bis)hydroxymethyl)-5.5-dimethylmidazolidine-2.4-dione
C&L Inventory
2,4-Imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
C&L Inventory
DMDM Hydantoin
Registration dossier
DMDMH
Registration dossier
oxybenzone
TRADE Names:
Dantogard XL-1000
Registration dossier
DMDM Hydantoin
Registration dossier
Glydant XL-1000
