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DODECAMETHYLCYCLOHEXASILOXANE = D6 = CYCLOMETHICONE 6
CAS Number: 540-97-6
EC Number: 208-762-8
MDL number: MFCD00144215
Empirical Formula (Hill Notation): C12H36O6Si6
Dodecamethylcyclohexasiloxane is an organosilicon compound.
Dodecamethylcyclohexasiloxane, also known as D6, is an industrial chemical.
Dodecamethylcyclohexasiloxane is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Dodecamethylcyclohexasiloxane is Clear Colourless Liquid.
There is no known natural source of Dodecamethylcyclohexasiloxane.
Dodecamethylcyclohexasiloxane, also known as cyclohexasiloxane or D6, belongs to a group of cyclic volatile methyl-siloxanes (cVMS) with relatively low molecular weight (< 600 g/mol) and high vapor pressure.
Dodecamethylcyclohexasiloxane, contains six repeating units of silicon (Si) and oxygen (O) atoms in a closed loop, giving it a “cyclic” structure.
The cyclosiloxanes octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), and Dodecamethylcyclohexasiloxane (D6) are cyclic volatile methyl siloxane (cVMS) substances with four, five, and six siloxane groups, respectively.
A siloxane is a functional group in organosilicon chemistry with the Si−O−Si linkage.
The parent siloxanes include the oligomeric and polymeric hydrides with the formulae H(OSiH2)nOH and (OSiH2)n.
Siloxanes also include branched compounds, the defining feature of which is that each pair of silicon centres is separated by one oxygen atom.
The siloxane functional group forms the backbone of silicones, the premier example of which is polydimethylsiloxane.
The functional group R3SiO− (where the three Rs may be different) is called siloxy.
Cyclosiloxanes are basic members of the broad family of silicone materials.
All silicone materials share a common chemistry but each substance is different with regard to its properties and use.
D4, D5 and Dodecamethylcyclohexasiloxane are the three cyclosiloxanes in commercial production and their use has been proven safe for human health and the environment.
This family includes several categories of substances:
*hexamethylcyclotrisiloxane (D3);
*octamethylcyclotetrasiloxane (D4);
*decamethylcyclopentasiloxane (D5);
*dodecamethylcyclohexasiloxane (D6)
*dodecamethylcycloheptasiloxane (D7).
The term "silicone" can also be used to refer to siloxanes.
Siloxanes, including the cyclic siloxanes octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), and Dodecamethylcyclohexasiloxane (D6) are among the most extensively studied materials used in consumer and industrial applications today.
Dodecamethylcyclohexasiloxane, more commonly known as Dodecamethylcyclohexasiloxane, contains six repeating units of silicon (Si) and oxygen (O) atoms in a closed loop, giving it a "cyclic" structure.
When used as an intermediate during the manufacturing process, virtually all Dodecamethylcyclohexasiloxane is consumed with only a tiny amount remaining in final products.
USES and APPLICATIONS of DODECAMETHYLCYCLOHEXASILOXANE:
-Cosmetic Uses:
*hair conditioning
*skin conditioning
*skin conditioning - emollient solvents
-Dodecamethylcyclohexasiloxane is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
-Dodecamethylcyclohexasiloxane is used in the following products: washing & cleaning products, polishes and waxes and cosmetics and personal care products.
-Other release to the environment of Dodecamethylcyclohexasiloxane is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
-Dodecamethylcyclohexasiloxane is used in the following products: cosmetics and personal care products, polishes and waxes, washing & cleaning products and semiconductors.
-Dodecamethylcyclohexasiloxane is used in the following areas: health services and formulation of mixtures and/or re-packaging.
-Dodecamethylcyclohexasiloxane is found or used in the manufacture of a wide variety of products.
-Dodecamethylcyclohexasiloxane is a silicone-based emollient.
-A cyclic volatile methylsiloxane (cVMS) used in cosmetic and personal care products, Dodecamethylcyclohexasiloxane can be used in dermal exposure and inhalation toxicity study.
-Dodecamethylcyclohexasiloxanes are used as fragrance carriers or solvents in household products, personal care products, cleaning agents and as precursors in the manufacture of silicone polymers.
-Dodecamethylcyclohexasiloxane is used in cosmetic and personal care products.
Dodecamethylcyclohexasiloxane is Used in dermal exposure
-Dodecamethylcyclohexasiloxane is used in cosmetic and personal care products.
-Dodecamethylcyclohexasiloxane is used in dermal exposure and inhalation toxicity study.
-The most important worldwide use of Dodecamethylcyclohexasiloxane is as an ingredient in the formulation of personal care products and as an intermediate in the production of polydimethylsiloxanes (PDMS) silicone polymers.
-The predominant use of Dodecamethylcyclohexasiloxane worldwide and in Canada is in blending and formulating consumer products and manufacturing silicone polymers.
-Dodecamethylcyclohexasiloxane is used in personal care products such as hair/skin care products, antiperspirants and deodorants.
-Biomedical uses of silicones include medical devices, blood-handling equipment, as a blood defoaming agent, as protective barriers, lubricants and as surface treatment of wound dressings.
-Silicone fluids containing Dodecamethylcyclohexasiloxane have also been approved as active and non-active ingredients in pharmaceuticals in Canada, the most common use being in anti-flatulence drugs.
-Dodecamethylcyclohexasiloxane is also used in industrial processes (as a defoamer, surfactant in certain pesticide products); in lubricants, cleaning products, sealants, adhesives, waxes, polishes and coatings.
-Siloxanes are manmade and have many commercial and industrial applications because of the compounds’ hydrophobicity, low thermal conductivity, and high flexibility.
-Dodecamethylcyclohexasiloxane is an odorless, colorless liquid mostly used as an intermediate or basic raw material in the production silicone rubbers, gels and resins.
-Dodecamethylcyclohexasiloxane can also be used as an ingredient in silicone mixtures used in cosmetic applications such as skin creams and deodorants, where D6 Siloxane may be labelled "cyclomethicone" or "cyclohexasiloxane".
-In personal care products, cyclosiloxanes act as “carriers”, allowing products to spread smoothly and easily and providing a silky feel during application.
-Dodecamethylcyclohexasiloxane is an odorless, colorless liquid mostly used as an intermediate or basic raw material in the production silicone rubbers, gels and resins.
-Dodecamethylcyclohexasiloxane can also be used as an ingredient in silicone mixtures used in cosmetic applications such as skin creams and deodorants.
-When Dodecamethylcyclohexasiloxane is used as an intermediate during the manufacturing process, virtually all Dodecamethylcyclohexasiloxane is consumed with only a tiny amount remaining in final products.
-Dodecamethylcyclohexasiloxane can also be used as an ingredient in silicone mixtures used in cosmetic applications such as skin creams and sunscreen, where Dodecamethylcyclohexasiloxane may be labelled “cyclomethicone” or “cyclohexasiloxane”.
-Dodecamethylcyclohexasiloxane imparts several benefits in personal care formulations, such as silkiness for conditioners, extra volume in lip glosses, and easy application in deodorants.
This product has a Dodecamethylcyclohexasiloxane content of 94%.
-Cyclosiloxanes are used in the manufacture of silicones, in combination or alone in personal care products, and as carriers, lubricants and solvents in a variety of commercial applications.
-Their use in cosmetics is one of their most important applications.
-D5 and Dodecamethylcyclohexasiloxane are commonly used in cosmetics as emollients, hair and skin conditioning ingredients, and solvents.
-The ingredients can be used in hair conditioning products where the product is washed off when used or in skincare products, personal deodorants, and colour cosmetics where the product is left on the skin.
-Cyclic siloxanes are starting materials for silicone polymers and are used in detergents and cleaning agents, polishes, waxes, cosmetics and personal care products.
-Dodecamethylcyclohexasiloxane is used Plasticizers, solvents, humectants, processing aids, lubricants, release agents, antifoams.
-Silicone compounds D4 (cyclotetrasiloxane), D5 (cyclopentasiloxane), and Dodecamethylcyclohexasiloxane are often found in personal care products and flow into the environment along with waste water.
They are also important source materials for certain silicones and are often found as residues in finished products.
-Basic members of the broad family of silicone materials, all cyclotetrasiloxane (D4), cyclopentasiloxane (D5), Dodecamethylcyclohexasiloxane are volatile oils with a cyclic chemical structure and various properties.
They are widely used because of the smooth and refreshing feeling they create.
-They are usually present in cosmetic products (make-up, cream, deodorant, etc.) and more widely in certain cleaning products or paints.
-Organosiloxanes are widely used in personal care products because they provide desirable properties in cosmetic products.
-These compounds are octamethylcyclotetrasiloxane (D4), decamethylcyclotetrasiloxane (D5) and Dodecamethylcyclohexasiloxane (D6).
These compounds are cyclic methyl siloxane substances containing four, five and six siloxane groups, respectively, and they have a mild and refreshing effect in cosmetic products.
PHYSICAL and CHEMICAL PROPERTIES of DODECAMETHYLCYCLOHEXASILOXANE:
Molecular Weight: 444.92
Physical state: liquid
Color: colorless
Odor: No data available
Melting point/freezing point:
Melting point/range: -3 °C
Initial boiling point and boiling range: 128 °C at 20 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 17,22 %(V) at 758 - 772 hPa
Lower explosion limit: 0,43 %(V) at 1011 - 1029 hPa
Flash point 91 °C - closed cup - ASTM D 93
Autoignition temperature: 368 - 371 °C
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00001 g/l - insoluble
Partition coefficient: log Pow: 8,87 at 23,6 °C n-octanol/water
Vapor pressure: 0,046 hPa at 25 °C
Density: 0,959 g/cm3
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Appearance: colorless clear oily liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.96720 @ 25.00 °C.
Refractive Index: 1.40150 @ 20.00 °C.
Melting Point: -3.00 °C. @ 760.00 mm Hg
Boiling Point: 245.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.022500 mmHg @ 25.00 °C. (est)
Flash Point: 256.00 °F. TCC ( 124.40 °C. ) (est)
Soluble in:
water, 0.005007 mg/L @ 25 °C (est)
water, 0.0051 mg/L @ 25 °C (exp)
Molecular Weight: 444.92
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 0
Exact Mass: 444.11274807
Monoisotopic Mass: 444.11274807
Topological Polar Surface Area: 55.4 Ų
Heavy Atom Count: 24
Formal Charge: 0
Complexity: 320
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Melting point: -3°C
Boiling point: 245 °C
Density: 0,959 g/cm3
refractive index: 1.4015
Flash point: >76°C
storage temp.: 2-8°C
solubility: Chloroform (Sparingly), Ethyl Acetate (Slightly)
form: liquid
color: Colourless
Specific Gravity: 0.9672
Hydrolytic Sensitivity 1: no significant reaction with aqueous systems
Merck: 14,3403
FIRST AID MEASURES of DODECAMETHYLCYCLOHEXASILOXANE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available
ACCIDENTAL RELEASE MEASURES of DODECAMETHYLCYCLOHEXASILOXANE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of DODECAMETHYLCYCLOHEXASILOXANE:
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of DODECAMETHYLCYCLOHEXASILOXANE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
not required
*Respiratory protection:
Not required; except in case of aerosol formation.
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of DODECAMETHYLCYCLOHEXASILOXANE:
-Precautions for safe handling:
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.
*Hygiene measures:
Change contaminated clothing.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
STABILITY and REACTIVITY of DODECAMETHYLCYCLOHEXASILOXANE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
SYNONYMS:
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane
DODECAMETHYLCYCLOHEXASILOXANE
Cyclohexasiloxane, dodecamethyl-
Cyclomethicone 6
2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
UNII-XHK3U310BA
XHK3U310BA
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane
HSDB 7723
dodecamethyl cyclohexasiloxane
SCHEMBL93785
DTXSID6027183
IUMSDRXLFWAGNT-UHFFFAOYSA-
CHEBI:191103
AKOS015839990
ZINC169794506
FS-5671
DB-008587
D2040
FT-0625566
S08515
T71035
Dodecamethylcyclohexasiloxane, analytical standard
A914553
Q27293843
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane #
Cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane 95%
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane, AldrichCPR
Cyclomethicone 6, United States Pharmacopeia (USP) Reference Standard
2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexa
Cyclohexasiloxane, dodecamethyl-
CYCLOHEXASILOXANE
Cyclohexasiloxane 6
Dow Corning 246 Fluid
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
SH 246;DC 246 Fluid
Dow Corning 246
Cyclomethicone 6
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane
DC 246 Fluid
Dodecamethylhexacyclosiloxane
Dow Corning 246 Fluid
SH 246
Cyclomethicone 6
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane
Cyclohexasiloxane, dodecamethyl
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
Cyclohexadimethylsiloxane
Dodecamethylcyclohexasiloxane
Hexadecamethylcyclohexasiloxane
Xiameter PMX 0246
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane
Cyclohexasiloxane, dodecamethyl-
dodecamethyl-cyclohexasiloxan
DODECAMETHYLCYCLOHEXASILOXANE
CYCLOHEXASILOXANE
CYCLOHEXASILOXANE,DODECAM
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethyl-1,3,5,7,9,11-hexao
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethyl-2,4,6,8,10,12-hexasila-1,3,5,7,9,11-hexaoxacyclododecane
