DODECANOL

CAS Number  : 112-53-8 
EC  Number  : 203-982-0
Molecular Formula    : C12H26O 
Molecular Weight    : 186.33
Appearance     : Colorless solid
Density             : 0.8309
Melting point     : 24 °C
Boiling point     : 259 °C

Preferred IUPAC name : 
-Dodecan-1-ol

Other names : 
-Dodecanol
-1-Dodecanol
-Dodecyl alcohol
-Lauryl alcohol

Dodecanol or lauryl alcohol, is an organic compound produced industrially from palm kernel oil or coconut oil. 
Dodecanol is a fatty alcohol. 
Sulfate esters of Dodecanol, especially sodium lauryl sulfate, are very widely used as surfactants. 
Dodecanol, ammonium lauryl sulfate, and sodium laureth sulfate are all used in shampoos. 
Dodecanol is tasteless and colorless with a floral odor.

Production and use of Dodecanol
In 1993, the European demand of dodecanol was around 60 thousand tons per year (Tt/a). 
Dodecanol can be obtained from palm kernel or coconut oil fatty acids and methyl esters by hydrogenation.
Dodecanol may also be produced synthetically via the Ziegler process. 
A classic laboratory method involves Bouveault-Blanc reduction of ethyl laurate.

Dodecanol is used to make surfactants, lubricating oils, pharmaceuticals, in the formation of monolithic polymers and as a flavor enhancing food additive. 
In cosmetics, dodecanol is used as an emollient. 
Dodecanol is also the precursor to dodecanal, an important fragrance, and 1-bromododecane, an alkylating agent for improving the lipophilicity of organic molecules.

Physicochemical Information of Dodecanol
Boiling point    : 229 °C
Density     : 0.833 g/cm3 (24 °C)
Flash point    : 121 °C
Ignition temperature    : 255 °C
Melting Point     : 24 - 27 °C
Vapor pressure     : 0.1 hPa (20 °C)
Solubility     : 0.004 g/l

Dodecanol is a long chain alkyl alcohol.
Dodecanols density and viscosity over a temperature range, 303.15 to 323.15K have been determined.
The thermodynamics of the interaction between 1-dodecanol and sodium dodecyl sulfate (SDS) micellar solutions has been reported.
This solvent meets ACS specifications and can be used for processes requiring strict quality conditions such as analytical testing.

Application of Dodecanol
Dodecanol may be used in the synthesis of the following:
Monododecyl glyceryl ethers via etherification by reacting with glycerol in the presence of 10mol% of 1-bromododecane.
ω- and (ω-1)-Hydroxy derivatives via hydroxylation reaction catalyzed by frog liver microsomes.
Dodecanal via oxidation in the presence of sodium bromate and ruthenium catalyst.
Dodecanol may be used to extract polycyclic aromatic hydrocarbons (PAHs) from water samples via dispersive liquid-liquid microextraction technique.

Dodecanol, also known by its IUPAC name 1-dodecanol or dodecan-1-ol, and by its trivial name dodecyl alcohol and lauryl alcohol, is a fatty alcohol. 
Dodecanol is a colourless, water insoluble solid of melting point 24 °C and boiling point 259 °C. 
Dodecanol has a floral odor. 
Dodecanol can be obtained from palm kernel or coconut oil fatty acids and methyl esters by reduction.

Dodecanol is used to make surfactants, lubricating oils, and pharmaceuticals.
In cosmetics, dodecanol is used as an emollient.
Dodecanol is used as a cosmetic, textile auxiliaries, synthetic oil, emulsifiers and flotation agent of raw materials, a detergent raw material, a foaming agent of the toothpaste.

Applications of Dodecanol
Dodecanol is used as a cosmetic, textile auxiliaries, synthetic oil, emulsifiers and flotation agent of raw materials, a detergent raw material, a foaming agent of the toothpaste.

Dodecanol, or dodecanol, also known by its IUPAC name 1-dodecanol or dodecan-1-ol, and by its trivial name dodecyl alcohol and lauryl alcohol, is a fatty alcohol. 
Dodecanol is a colourless, water insoluble solid of melting point 24 degree centigrade and boiling point 259 degree centigrade. 
Dodecanol has a floral odor. 
Dodecanol can be obtained from palm kernel or coconut oil fatty acids and methyl esters by reduction.

Dodecanol is a fatty alcohol which is a tasteless, colorless solid with a floral smell. 
Dodecanol is obtained from palm kernel or coconut oil and is used as a precursor to the fragrance dodecanal. 
In pharmaceutical use, Dodecanol makes lubricating oils, surfactants, and as an emollient. 
Ungraded products supplied by TCI America are generally suitable for common industrial uses or for research purposes but typically are not suitable for human consumption or therapeutic use.

Use and Manufacturing of Dodecanol
Used to manufacture sulfuric acid esters (wetting agents) and in synthetic detergents, lube additives, pharmaceuticals, rubber, textiles, and perfumes; Also used as a flavoring agent and as a foam stabilizer for alcohol sulfate surfactants; Used to make surfactants for detergents, cleaning products, shampoos, cosmetics, lubricants, wetting agents, emulsifiers, dispersing agents, and antioxidants; Also used to make biocides and disinfectants; 1-Dodecanol is used in foam control, aluminum rolling, metalworking, and in the rubber, textiles, cosmetics, and perfume industries; Also used as a froth flotation agent and a flavoring ingredient in non-alcoholic beverages, ice cream, candy, baked goods, chewing gum, and syrups;Used as Lepidoptera pheromone in apple and pear orchards

Industry Uses of Dodecanol
-Antioxidant
-Cleaning agent
-Fragrance
-Intermediate
-Lubricants and lubricant additives
-Lubricating agent
-Not Known or Reasonably Ascertainable
-Processing aids not otherwise specified
-Solubility enhancer
-Solvent
-Surfactant (surface active agent)

Consumer Uses of Dodecanol
-Cleaning agent
-Fragrance
-Lubricants and lubricant additives
-Lubricating agent
-Pigment
-Surfactant (surface active agent)

First Aid Measures of Dodecanol

Inhalation: 
If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. 
For breathing difficulties, oxygen may be necessary. 
Call a physician if symptoms develop  or persist.

Skin Contact: 
Take off immediately all contaminated clothing. 
Get medical attention if irritation develops and persists. 
Wash skin thoroughly with soap and water for several minutes.

Eye Contact: 
Remove contact lenses, if present and easy to do. 
Get medical attention if irritation develops and persists. 
Promptly wash eyes with plenty of water while lifting the eye lids.

Ingestion: 
Call a physician or poison control center immediately. 
If swallowed, rinse mouth with water (only if the person is conscious). 
Do not induce vomiting. 
If vomiting occurs, the head should be kept low so that stomach vomit doesn't enter the lungs.
Severe eye irritation. 
Symptoms may include stinging, tearing, redness, swelling, and blurred vision.
Skin irritation. May cause redness and pain.

Substance identity

EC / List no.: 203-982-0
CAS no.: 112-53-8
Mol. formula: C12H26O

Hazard classification & labelling of DODECANOL
Danger! According to the classification provided by companies to ECHA in REACH registrations this substance is very toxic to aquatic life with long lasting effects, is very toxic to aquatic life, causes serious eye damage, is a highly flammable liquid and vapour, is harmful if swallowed, is harmful in contact with skin, may cause respiratory irritation and may cause drowsiness or dizziness.

About DODECANOL
DODECANOL is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.
DODECANOL is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses of DODECANOL
DODECANOL is used in the following products: washing & cleaning products, coating products, biocides (e.g. disinfectants, pest control products), anti-freeze products, lubricants and greases, polishes and waxes and finger paints.
Other release to the environment of DODECANOL is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Article service life of DODECANOL
Release to the environment of DODECANOL can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). 
Other release to the environment of DODECANOL is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials). 
DODECANOL can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material) and plastic (e.g. food packaging and storage, toys, mobile phones).

Widespread uses by professional workers of DODECANOL
DODECANOL is used in the following products: lubricants and greases, coating products, fillers, putties, plasters, modelling clay, biocides (e.g. disinfectants, pest control products), adhesives and sealants, non-metal-surface treatment products, air care products, anti-freeze products, washing & cleaning products and welding & soldering products.
DODECANOL is used in the following areas: building & construction work.
DODECANOL is used for the manufacture of: , mineral products (e.g. plasters, cement), machinery and vehicles, rubber products, plastic products and fabricated metal products.
Other release to the environment of DODECANOL is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Formulation or re-packing of DODECANOL
DODECANOL is used in the following products: laboratory chemicals, pH regulators and water treatment products, inks and toners, polymers, cosmetics and personal care products, coating products, fillers, putties, plasters, modelling clay and finger paints.
DODECANOL has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of DODECANOL can occur from industrial use: formulation of mixtures, formulation in materials and as an intermediate step in further manufacturing of another substance (use of intermediates).

Uses at industrial sites of DODECANOL
DODECANOL is used in the following products: lubricants and greases, fillers, putties, plasters, modelling clay, coating products, adhesives and sealants, non-metal-surface treatment products, polymers and pH regulators and water treatment products.
DODECANOL is used in the following areas: building & construction work.
DODECANOL is used for the manufacture of: chemicals, , mineral products (e.g. plasters, cement) and machinery and vehicles.
Release to the environment of DODECANOL can occur from industrial use: in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and as processing aid.

Manufacture of DODECANOL
Release to the environment of DODECANOL can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

Synonyms:
1-Dodecanol
Dodecan-1-ol
Dodecan-1-ol
dodecan-1-ol
1-Dodecanol
1-Dodecanol
1-dodecanol
1-Dodecanol
Alcohol C12
Alcohol, C12
Dodecan-1-ol
dodecan-1-ol
Dodecan-1-ol
dodecan-1-ol
Dodecyl alcohol
Lauryl alcohol
Palmerol 1214 NFPalmerol 1216
CO-1214
CO-1270
ECOROL 02
ECOROL 12/98
ECOROL 12/99
ECOROL 24
ECOROL 24/55
ECOROL 26
ECOROL 28
Fatty alcohol 12 ...
Fatty alcohol 1214 ...
Fatty alcohol 1216 ...
Kalcol
Lauryl Alcohol
Leunapol-FA 12
Nacol 12 ...
Nafol 1214 ...
1-Dodecanol
Dodecan-1-ol
1173838-88-4
1173838-88-4
1322-35-6
1322-35-6
68855-55-0
68855-55-0
8014-32-2
8014-32-2
8032-08-4
8032-08-4
8032-09-5
8032-09-5
8032-10-8
8032-10-8
1-DODECANOL
Dodecan-1-ol
Dodecyl alcohol
Dodecanol
Lauryl alcohol
112-53-8
n-Dodecyl alcohol
Undecyl carbinol
Dodecylalcohol
Lauric alcohol
Laurinic alcohol
1-Dodecyl alcohol
Pisol
n-Dodecan-1-ol
Duodecyl alcohol
1-Hydroxydodecane
Siponol L5
Karukoru 20
Lauroyl alcohol
Siponol 25
Lorol 5
Lorol 7
n-Dodecanol
Lauryl 24
Alcohol C-12
Alfol 12
Lorol 11
Sipol L12
Dytol J-68
Siponol L2
Cachalot L-50
Cachalot L-90
Dodecyl alcoho
n-Lauryl alcohol
C12 alcohol
Hainol 12SS
Hydroxydodecane
Conol 20P
Conol 20PP
Lorol
Alcohols, C8-18
EPAL 12
Adol 10
Adol 12
Dodecanol-1
n-Lauryl alcohol, primary
Nacol 12-96
Alcohol C12
C8-18 Alcohols
FEMA No. 2617
NAA 42
CO-1214
Lipocol L
CO-1214N
CO-1214S
MFCD00004753
S 1298
MA-1214
Lorol C12
Co-1214S1-dodecanol
27342-88-7
68551-07-5
CHEBI:28878
178A96NLP2
NSC-3724
DSSTox_CID_6918
DSSTox_RID_78253
DSSTox_GSID_26918
Fatty alcohol(C12)
Adol 11
Lorol C 12
FEMA Number 2617
Dytol J-68 (VAN)
Lorol C 12/98
1DO
CAS-112-53-8
CCRIS 662
Dodecanol, 1-
HSDB 1075
NSC 3724
EINECS 203-982-0
BRN 1738860
Fatty (C8-C18) alcohol
laurylalcohol
Lorol special
UNII-178A96NLP2
AI3-00309
EINECS 271-359-0
Philcohol 1200
LAUREX NC
LAUREX L1
Lorol C8-C10 special
Lorol C12-C14
1-DODECANOL [MI]
1-Dodecanol, 98.0%
EC 203-982-0
SCHEMBL6844
1-DODECANOL [HSDB]
LAURYL ALCOHOL [FCC]
4-01-00-01844 (Beilstein Handbook Reference)
CHEMBL24722
LAURYL ALCOHOL [FHFI]
LAURYL ALCOHOL [INCI]
C12H25OH
WLN: Q12
Lauryl alcohol, >=98%, FG
NACOL 12-99 ALCOHOL
DTXSID5026918
LAURYL ALCOHOL [USP-RS]
1-dodecanol (ACD/Name 4.0)
1-Dodecanol, analytical standard
ALFOL 1216 CO ALCOHOL
NSC3724
1-Dodecanol, reagent grade, 98%
BCP29203
CS-D1360
HY-Y0289
ZINC1529403
Tox21_202124
Tox21_300120
LMFA05000001
STL301829
CACHALOT L-90 LAURYL ALCOHOL
Co 12Co-1214Co-1214N
AKOS009031450
DB06894
1-Dodecanol, ACS reagent, >=98.0%
NCGC00164341-01
NCGC00164341-02
NCGC00164341-03
NCGC00253987-01
NCGC00259673-01
CS-16955
1-Dodecanol 100 microg/mL in Acetonitrile
DB-003637
1-Dodecanol, SAJ special grade, >=97.0%
1-Dodecanol, Selectophore(TM), >=98.0%
1-dodecanol; dodecyl alcohol; lauryl alcohol
D0978
FT-0607710
FT-0693265
Oxo alcohol still bottoms (C8-18 alcohols)
1-Dodecanol, Vetec(TM) reagent grade, 98%
EN300-20043
C02277
Q161617
Q-200121
Dodecan-1-ol;Dodecyl alcohol;Lauryl alcohol;Dodecanol
Z104476554
Lauryl alcohol, United States Pharmacopeia (USP) Reference Standard
Dodecan-1-ol [Wiki]
112-53-8 [RN]
178A96NLP2
1-Dodecanol [ACD/Index Name] [ACD/IUPAC Name]
1-Dodecanol [German] [ACD/Index Name] [ACD/IUPAC Name]
1-Dodécanol [French] [ACD/IUPAC Name]
1-Dodecyl alcohol
1-Hydroxydodecane
203-982-0 [EINECS]
278-306-0 [EINECS]
DODECANOL [Wiki]
Dodecyl alcohol
Hydroxydodecane
Lauryl Alcohol
n-Dodecanol
n-Lauryl alcohol
1-Dodecan-d25-ol
264-118-6 [EINECS]
272-490-6 [EINECS]
4-01-00-01844 (Beilstein Handbook Reference) [Beilstein]
4-01-00-01864 (Beilstein Handbook Reference) [Beilstein]
4-01-00-01876 (Beilstein Handbook Reference) [Beilstein]
4-01-00-01888 [Beilstein]
Adol 52 NF [NF]
Adol 52NF
AIDS471017
AIDS-471017
Alcohol stearylicus
Atalco C
Atalco S
Cetaffine
CETAL
Cetalol CA
Cetyl alcohol [NF]
Conol 20P
Conol 20PP
Crodacol C
Crodacol-CAS
Crodacol-CAT
Crodacol-S
CS-16955
Dodecan-1-al
Dodecanol (Lauryl Alcohol)
Dodecanol, 1-
Dodecyl alcoho
Dodecyl alcohol, Lauryl alcohol
dodecyl alcohol, reagent, acs
dodecyl-1-ol
Dodecyl-d25 alcohol
DODECYL-α-D-MALTOSIDE
Dodecyl-β-D-maltoside
Duodecyl alcohol
Dytol F-11
Dytol J-68 (VAN)
Dytol R-52
Elfacos C
Ethal [Wiki]
Ethol
Exxal 12
Hainol 12SS
Hyfatol
Hyfatol 16
Karukoru 20
Lanette K
Lanette Wax KS
Lanol C
Lanol S
Lauric alcohol
Laurinic alcohol
Lauroyl alcohol
LAURYL ALCOHOL[11,12-3H]
Lipocol L
LMFA05000061
LMT
LMU
Lorol
Lorol C 12
Lorol C12
Lorol special
Loxanol K
Loxanol K extra
LOXANOL V
Loxanwachs SK
Nacol 12-96
n-Cetyl alcohol
n-Dodecan-1-ol
n-dodecanol|dodecyl alcohol|dodecan-1-ol|lauric alcohol|lauryl alcohol|laurinic alcohol|lorol
N-DODECYL ALCOHOL
Pisol
Polaax
Q12 [WLN]
Sipol L12
Sipol S
Siponol CC
Siponol L2
Siponol L5
Siponol S
Siponol SC
Siponol wax-A
SSD AF
SSD RP
stenol
Steraffine
Undecyl carbinol
UNII:178A96NLP2
USP XIII stearyl alcohol [USP]
WLN: Q12
十二烷醇 [Chinese]