DODECANOL

Dodecanol is an organic compound produced industrially from palm kernel oil or coconut oil. 
Dodecanol is a fatty alcohol. 
Sulfate esters of Dodecanol, especially sodium lauryl sulfate, are very widely used as surfactants. 
Dodecanol, ammonium lauryl sulfate, and sodium laureth sulfate are all used in shampoos. 
Dodecanol is tasteless and colorless with a floral odor.

CAS Number: 112-53-8 
EC Number: 203-982-0
IUPAC Name: Dodecan-1-ol
Chemical Formula: C12H26O 

Other names: 1-Dodecanol, Dodecan-1-ol, Dodecan-1-ol, dodecan-1-ol, 1-Dodecanol, 1-Dodecanol, 1-Dodecanol, 1-Dodecanol, Alcohol C12, Alcohol, C12, Dodecan-1-ol, dodecan-1-ol, Dodecan-1-ol, dodecan-1-ol, Dodecyl alcohol, Lauryl alcohol, Palmerol 1214 NFPalmerol 1216, CO-1214, CO-1270, ECOROL 02, ECOROL 12/98, ECOROL 12/99, ECOROL 24, ECOROL 24/55, ECOROL 26, ECOROL 28, Fatty alcohol 12, Fatty alcohol 1214, Fatty alcohol 1216, Kalcol, Lauryl Alcohol, Leunapol-FA 12, Nacol 12, Nafol 1214, 1-Dodecanol, Dodecan-1-ol, Dodecyl alcohol, Dodecanol, Lauryl alcohol, 112-53-8, n-Dodecyl alcohol, Undecyl carbinol, Dodecylalcohol, Lauric alcohol, Laurinic alcohol, 1-Dodecyl alcohol, Pisol, n-Dodecan-1-ol, Duodecyl alcohol, 1-Hydroxydodecane, Siponol L5, Karukoru 20, Lauroyl alcohol, Siponol 25, Lorol 5, Lorol 7, n-Dodecanol, Lauryl 24, Alcohol C-12, Alfol 12, Lorol 11, Sipol L12, Dytol J-68, Siponol L2, Cachalot L-50, Cachalot L-90, Dodecyl alcoho, n-Lauryl alcohol, C12 alcohol, Hainol 12SS, Hydroxydodecane, Conol 20P, Conol 20PP, Lorol, Alcohols, C8-18, EPAL 12, Adol 10, Adol 12, Dodecanol-1, n-Lauryl alcohol, primary, Nacol 12-96, Alcohol C12, C8-18 Alcohols, FEMA No. 2617, NAA 42, CO-1214, Lipocol L, CO-1214N, CO-1214S, MFCD00004753, S 1298, MA-1214, Lorol C12, Co-1214S1-Dodecanol, 27342-88-7, 68551-07-5, CHEBI:28878, 178A96NLP2, NSC-3724, DSSTox_CID_6918, DSSTox_RID_78253, DSSTox_GSID_26918, Fatty alcohol(C12), Adol 11, Lorol C 12, FEMA Number 2617, Dytol J-68 (VAN), Lorol C 12/98, 1DO, CAS-112-53-8, CCRIS 662, Dodecanol, 1-, HSDB 1075, NSC 3724, EINECS 203-982-0, BRN 1738860, Fatty (C8-C18) alcohol, laurylalcohol, Lorol special, UNII-178A96NLP2, AI3-00309, EINECS 271-359-0, Philcohol 1200, LAUREX NC, LAUREX L1, WLN: Q12, Lauryl alcohol, >=98%, FG, NACOL 12-99 ALCOHOL, DTXSID5026918, LAURYL ALCOHOL [USP-RS], 1-Dodecanol (ACD/Name 4.0), 1-Dodecanol, analytical standard, ALFOL 1216 CO ALCOHOL, NSC3724, 1-Dodecanol, reagent grade, 98%, BCP29203, CS-D1360, HY-Y0289, ZINC1529403, Tox21_202124, Tox21_300120, LMFA05000001, STL301829, CACHALOT L-90 LAURYL ALCOHOL, Co 12Co-1214Co-1214N, AKOS009031450, DB06894, CS-16955, D0978, FT-0607710, FT-0693265, Dodecyl alcohol, Hydroxydodecane, Lauryl Alcohol, n-Dodecanol, n-Lauryl alcohol, 1-Dodecan-d25-ol, SSD AF, SSD RP, stenol, Steraffine, Undecyl carbinol, UNII:178A96NLP2, USP XIII stearyl alcohol [USP], WLN: Q12

Production and use of Dodecanol
In 1993, the European demand of Dodecanol was around 60 thousand tons per year (Tt/a). 
Dodecanol can be obtained from palm kernel or coconut oil fatty acids and methyl esters by hydrogenation.
Dodecanol may also be produced synthetically via the Ziegler process. 
A classic laboratory method involves Bouveault-Blanc reduction of ethyl laurate.

Dodecanol is used to make surfactants, lubricating oils, pharmaceuticals, in the formation of monolithic polymers and as a flavor enhancing food additive. 
In cosmetics, Dodecanol is used as an emollient. 
Dodecanol is also the precursor to dodecanal, an important fragrance, and 1-bromododecane, an alkylating agent for improving the lipophilicity of organic molecules.

Dodecanol is a long chain alkyl alcohol.
Dodecanols density and viscosity over a temperature range, 303.15 to 323.15K have been determined.
The thermodynamics of the interaction between 1-Dodecanol and sodium dodecyl sulfate (SDS) micellar solutions has been reported.
This solvent meets ACS specifications and can be used for processes requiring strict quality conditions such as analytical testing.

Application of Dodecanol
Dodecanol may be used in the synthesis of the following:
Monododecyl glyceryl ethers via etherification by reacting with glycerol in the presence of 10mol% of 1-bromododecane.
ω- and (ω-1)-Hydroxy derivatives via hydroxylation reaction catalyzed by frog liver microsomes.
Dodecanal via oxidation in the presence of sodium bromate and ruthenium catalyst.
Dodecanol may be used to extract polycyclic aromatic hydrocarbons (PAHs) from water samples via dispersive liquid-liquid microextraction technique.

Dodecanol, also known by its IUPAC name 1-Dodecanol or dodecan-1-ol, and by its trivial name dodecyl alcohol and lauryl alcohol, is a fatty alcohol. 
Dodecanol is a colourless, water insoluble solid of melting point 24 °C and boiling point 259 °C. 
Dodecanol has a floral odor. 
Dodecanol can be obtained from palm kernel or coconut oil fatty acids and methyl esters by reduction.

Dodecanol is used to make surfactants, lubricating oils, and pharmaceuticals.
In cosmetics, Dodecanol is used as an emollient.
Dodecanol is used as a cosmetic, textile auxiliaries, synthetic oil, emulsifiers and flotation agent of raw materials, a detergent raw material, a foaming agent of the toothpaste.

Applications of Dodecanol
Dodecanol is used as a cosmetic, textile auxiliaries, synthetic oil, emulsifiers and flotation agent of raw materials, a detergent raw material, a foaming agent of the toothpaste.

Dodecanol, or Dodecanol, also known by its IUPAC name 1-Dodecanol or dodecan-1-ol, and by its trivial name dodecyl alcohol and lauryl alcohol, is a fatty alcohol. 
Dodecanol is a colourless, water insoluble solid of melting point 24 degree centigrade and boiling point 259 degree centigrade. 
Dodecanol has a floral odor. 
Dodecanol can be obtained from palm kernel or coconut oil fatty acids and methyl esters by reduction.

Dodecanol is a fatty alcohol which is a tasteless, colorless solid with a floral smell. 
Dodecanol is obtained from palm kernel or coconut oil and is used as a precursor to the fragrance dodecanal. 
In pharmaceutical use, Dodecanol makes lubricating oils, surfactants, and as an emollient. 
Ungraded products supplied by TCI America are generally suitable for common industrial uses or for research purposes but typically are not suitable for human consumption or therapeutic use.

Use and Manufacturing of Dodecanol
Used to manufacture sulfuric acid esters (wetting agents) and in synthetic detergents, lube additives, pharmaceuticals, rubber, textiles, and perfumes; Also used as a flavoring agent and as a foam stabilizer for alcohol sulfate surfactants; Used to make surfactants for detergents, cleaning products, shampoos, cosmetics, lubricants, wetting agents, emulsifiers, dispersing agents, and antioxidants; Also used to make biocides and disinfectants; 1-Dodecanol is used in foam control, aluminum rolling, metalworking, and in the rubber, textiles, cosmetics, and perfume industries; Also used as a froth flotation agent and a flavoring ingredient in non-alcoholic beverages, ice cream, candy, baked goods, chewing gum, and syrups;Used as Lepidoptera pheromone in apple and pear orchards

Industry Uses of Dodecanol
Antioxidant
Cleaning agent
Fragrance
Intermediate
Lubricants and lubricant additives

Lubricating agent
Not Known or Reasonably Ascertainable
Processing aids not otherwise specified
Solubility enhancer
Solvent
Surfactant (surface active agent)

Consumer Uses of Dodecanol
Cleaning agent
Fragrance
Lubricants and lubricant additives
Lubricating agent
Pigment
Surfactant (surface active agent)

First Aid Measures of Dodecanol
Inhalation: 
If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. 
For breathing difficulties, oxygen may be necessary. 
Call a physician if symptoms develop  or persist.

Skin Contact: 
Take off immediately all contaminated clothing. 
Get medical attention if irritation develops and persists. 
Wash skin thoroughly with soap and water for several minutes.

Eye Contact: 
Remove contact lenses, if present and easy to do. 
Get medical attention if irritation develops and persists. 
Promptly wash eyes with plenty of water while lifting the eye lids.

Ingestion: 
Call a physician or poison control center immediately. 
If swallowed, rinse mouth with water (only if the person is conscious). 
Do not induce vomiting. 
If vomiting occurs, the head should be kept low so that stomach vomit doesn't enter the lungs.
Severe eye irritation. 
Symptoms may include stinging, tearing, redness, swelling, and blurred vision.
Skin irritation. May cause redness and pain.

Hazard classification & labelling of Dodecanol
Danger! According to the classification provided by companies to ECHA in REACH registrations this substance is very toxic to aquatic life with long lasting effects, is very toxic to aquatic life, causes serious eye damage, is a highly flammable liquid and vapour, is harmful if swallowed, is harmful in contact with skin, may cause respiratory irritation and may cause drowsiness or dizziness.

Dodecanol is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.
Dodecanol is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Dodecanol is used in the following products: washing & cleaning products, coating products, biocides (e.g. disinfectants, pest control products), anti-freeze products, lubricants and greases, polishes and waxes and finger paints.
Other release to the environment of Dodecanol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Release to the environment of Dodecanol can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). 

Other release to the environment of Dodecanol is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials). 

Dodecanol can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material) and plastic (e.g. food packaging and storage, toys, mobile phones).

Dodecanol is used in the following products: lubricants and greases, coating products, fillers, putties, plasters, modelling clay, biocides (e.g. disinfectants, pest control products), adhesives and sealants, non-metal-surface treatment products, air care products, anti-freeze products, washing & cleaning products and welding & soldering products.

Dodecanol is used in the following areas: building & construction work.
Dodecanol is used for the manufacture of: , mineral products (e.g. plasters, cement), machinery and vehicles, rubber products, plastic products and fabricated metal products.
Other release to the environment of Dodecanol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Dodecanol is used in the following products: laboratory chemicals, pH regulators and water treatment products, inks and toners, polymers, cosmetics and personal care products, coating products, fillers, putties, plasters, modelling clay and finger paints.
Dodecanol has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Dodecanol can occur from industrial use: formulation of mixtures, formulation in materials and as an intermediate step in further manufacturing of another substance (use of intermediates).

Dodecanol is used in the following products: lubricants and greases, fillers, putties, plasters, modelling clay, coating products, adhesives and sealants, non-metal-surface treatment products, polymers and pH regulators and water treatment products.
Dodecanol is used in the following areas: building & construction work.

Dodecanol is used for the manufacture of: chemicals, , mineral products (e.g. plasters, cement) and machinery and vehicles.
Release to the environment of Dodecanol can occur from industrial use: in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and as processing aid.

Release to the environment of Dodecanol can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.