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DOWANOL EPH GLYCOL ETHER

Dowanol EPH Glycol Ether improves polymer film formation, flow, leveling, and gloss development.
Dowanol EPH Glycol Ethers controlled evaporation rate helps prevent surface defects during drying.
Dowanol EPH Glycol Ether enhances penetration of active ingredients into soils and surface films.

CAS Number: 122-99-6
Molecular Formula: C8H10O2
Molecular Weight: 138.16
EINECS Number: 204-589-7

Synonyms: 2-PHENOXYETHANOL, Phenoxyethanol, 122-99-6, Ethylene glycol monophenyl ether, Phenyl cellosolve, Phenoxethol, Phenoxytol, Ethanol, 2-phenoxy-, 2-Phenoxyethan-1-Ol, Phenoxetol, Ethylene glycol phenyl ether, Rose ether, Phenoxyethyl alcohol, 1-Hydroxy-2-phenoxyethane, Arosol, Phenylmonoglycol ether, 2-Phenoxyethyl alcohol, Dowanol EPH Glycol Ether, Dowanol EPH Glycol Ether, Glycol monophenyl ether, 2-Hydroxyethyl phenyl ether, Emeressence 1160, Fenyl-cellosolve, 2-Fenoxyethanol, Fenylcelosolv, Emery 6705, beta-Hydroxyethyl phenyl ether, EGMPE, Dalpad A, Plastiazan-41, beta-Phenoxyethanol, DTXSID9021976, Newpol EFP, NSC-1864, HIE492ZZ3T, FEMA NO. 4620, DTXCID401976, CHEBI:64275, CPAP WIPES, VAXOL PURI, RefChem:55846, beta-Phenoxyethyl alcohol, MELAO DEODORANT Cream, MELAO COLOR HAIR WAX, 204-589-7, 2-Phenoxy-ethanol, MFCD00002857, Phenylglycol, 9004-78-8, .beta.-Hydroxyethyl phenyl ether, NSC 1864, Phenoxyethanol [NF], Ethylene glycol-monophenyl ether, PHE-G, .beta.-Phenoxyethyl alcohol, 2-Phenoxyethyl--d4 Alcohol, Phenoxyethanol (NF), NCGC00090731-01, NCGC00090731-05, Fenylcelosolv [Czech], 2-Fenoxyethanol [Czech], Fenyl-cellosolve [Czech], Plastiazan-41 [Russian], CAS-122-99-6, .beta.-Phenoxyethanol, HSDB 5595, EINECS 204-589-7, UNII-HIE492ZZ3T, BRN 1364011, AI3-00752()C, phenylcellosolve, CCRIS 9481, Ethoxylated phenol, 2-phenyloxyethanol, 2-phenoxy ethanol, Phenoxyethanol CRS, 2-(phenoxy)ethanol, Domiphen Impurity 4, 2-phenoxy-1-ethanol, beta-phenoxyethylalcohol, starbld0047047, PHE-S, 2-Phenoxyethanol, 9CI, 2-Phenoxyethanol, 99%, Phenoxyethanol (Standard), WLN: Q2OR, EC 204-589-7, PHENOXYETHANOL [II], 2-Phenoxyethanol-1,1-d2, SCHEMBL15708, SCHEMBL57755, 2-Phenoxyethanol, >=99%, PHENOXYETHANOL [HSDB], 4-06-00-00571 (Beilstein Handbook Reference), MLS002174254, ethyleneglycol monophenyl ether, Euxyl K 400 (Salt/Mix), ProClin® 8020 preservatives, SCHEMBL194335, SCHEMBL348920, SCHEMBL348921, Ethyleneglycol-monophenyl ether, 2-PHENOXYETHANOL [MI], PHENOXYETHANOL [MART.], orb1306704, orb3025203, SCHEMBL1679226, SCHEMBL4072387, SCHEMBL6721192, SCHEMBL8371561, SCHEMBL8535485, PHENOXYETHANOL [USP-RS], PHENOXYETHANOL [WHO-DD], CHEMBL1229846, SCHEMBL10611874, SCHEMBL10873485, SCHEMBL11659790, HY-B1729R, MSK2538, NSC1864, HMS2268A20, BB_SC-02741, HY-B1729, STR04582, WAA27338, Tox21_111002, Tox21_113532, Tox21_202111, Tox21_300842, BBL027410, EBC-26080, PHENOXYETHANOL [EP MONOGRAPH], SBB060485, STK802556, 2-Phenoxyethanol, analytical standard, Fungal Terminator [veterinary] (TN), AKOS000118741, Tox21_111002_1, DB11304, FP31791, NCGC00090731-02, NCGC00090731-03, NCGC00090731-04, NCGC00090731-06, NCGC00090731-07, NCGC00090731-08, NCGC00254745-01, NCGC00259660-01, 56257-90-0, DA-76810, Ethylene glycol monophenyl ether, >=90%, SMR000112131, ETHANOL,2-PHENOXY MFC8 H10 O2, CS-0013737, NS00002984, P0115, P1953, ST51046662, EN300-19339, 2-Phenoxyethanol, tested according to Ph.Eur., D08359, G74506, SBI-0653920.0001, F005091, Q418038, SR-01000838345, SR-01000838345-2, F1905-6997, Z104473570, Ethylene glycol monophenyl ether, SAJ first grade, >=95.0%, Phenoxyethanol, European Pharmacopoeia (EP) Reference Standard, Phenoxyethanol, United States Pharmacopeia (USP) Reference Standard, InChI=1/C8H10O2/c9-6-7-10-8-4-2-1-3-5-8/h1-5,9H,6-7H, 2-Phenoxyethanol, Pharmaceutical Secondary Standard; Certified Reference Material, Ethylene Glycol Monophenyl Ether Phenyl Cellosolve Phenyl Glycol;ETHYLENE GLYCOL MONOPHENYL ETHER FOR SYN;(2-Hydroxyethoxy)benzene;PhG;Protectol PE;ACETONITRILE ACS GRADE;beta-Phenoxyethanol;beta-phenoxyethanol[qr]

Dowanol EPH Glycol Ether is a trade name used by Dow for 2-phenoxyethanol, an aromatic glycol ether solvent with the molecular formula C₈H₁₀O₂.
Dowanol EPH Glycol Ether is a clear, colorless liquid with a mild, slightly rose-like odor and balanced solvency properties.
The designation “EPH” indicates a phenyl-containing glycol ether grade designed for strong organic solvency.

Dowanol EPH Glycol Ether consists of a phenyl (aromatic) ring linked to an ethylene glycol ether chain.
This structure provides both hydrophobic (aromatic) and hydrophilic (ether–alcohol) character.
As a result, it acts as an effective coupling solvent between water-based and organic systems.

Dowanol EPH Glycol Ether has a relatively high boiling point and low vapor pressure compared to lighter glycol ethers.
These properties reduce evaporation losses and improve handling safety.
Dowanol EPH Glycol Ether is miscible with many organic solvents and partially miscible with water.

In coatings and surface technology, Dowanol EPH Glycol Ether is used as a solvent and coalescing aid in water-borne paints and industrial coatings.
In adhesives and resin systems, Dowanol EPH Glycol Ether enhances solubility of binders, plasticizers, and additives.
Dowanol EPH Glycol Ether promotes formulation stability and compatibility between components.

This improves performance consistency and shelf life.
In personal care and cosmetic formulations, Dowanol EPH Glycol Ether (as phenoxyethanol) is widely used as a preservative solvent and stabilizer.
Dowanol EPH Glycol Ether helps dissolve fragrances and antimicrobial agents while maintaining product clarity.

Common products include creams, lotions, wipes, deodorants, and hair-care items.
In cleaning and disinfectant products, Dowanol EPH Glycol Ether improves wetting and antimicrobial effectiveness.
Its relatively low volatility makes it suitable for wipes and spray cleaners.

Toxicological considerations show low acute toxicity at regulated use levels.
However, concentrated exposure may cause skin or eye irritation and mild central nervous system effects.
Appropriate protective equipment and ventilation are recommended in industrial settings.

Regulatory status permits Dowanol EPH Glycol Ether use globally under defined concentration limits.
It appears in cosmetic, pharmaceutical, and industrial standards depending on purity grade.
Compliance depends on application type, exposure route, and regional regulations.

In summary, Dowanol EPH Glycol Ether is a phenyl-based glycol ether solvent grade of 2-phenoxyethanol.
Its combination of strong aromatic solvency, low volatility, and formulation compatibility makes it valuable across coatings, cosmetics, cleaners, adhesives, and specialty chemicals.
It remains widely used where controlled evaporation and reliable solvency are required.

Dowanol EPH Glycol Ether is used in many applications such as cosmetics, vaccines and pharmaceuticals as a preservative.
Dowanol EPH Glycol Ether is the organic compound with the formula C6H5OC2H4OH.
Dowanol EPH Glycol Ether can be classified as a glycol ether and a phenol ether.

Dowanol EPH Glycol Ether is a common preservative in vaccine formulations.
Dowanol EPH Glycol Ether has a faint rose-like aroma.
Dowanol EPH Glycol Ether is a trade name used by Dow Chemical for 2-phenoxyethanol, an aromatic glycol ether with the chemical formula C₈H₁₀O₂.

Melting point: 11–13 °C (lit.)
Boiling point: 247 °C (lit.)
Density: 1.102 g/mL at 25 °C (lit.)
Vapor density: 4.8 (vs air)
Vapor pressure: 0.01 mm Hg (20 °C)
Refractive index: n20/D 1.539
FEMA: 4620 | 2-Phenoxyethanol
Flash point: >230 °F
Storage temp.: Store below +30 °C
Solubility: Soluble; clear; colorless to very faintly yellow
pKa: 14.36 ± 0.10 (predicted)
Form: Liquid
Color: Clear, colorless
Specific gravity: 1.109 (20/4 °C)
pH: 7 (10 g/L, H₂O, 23 °C)
Odor: Faint aromatic odor
pH range: 7 at 10 g/L at 23 °C
Odor type: Floral
Viscosity: 29 mm²/s (20 °C)
Explosive limit: 1.4–9.0% (V)
Water solubility: 30 g/L (20 °C)
Merck: 14,7257
BRN: 1364011
Major application: Environmental
Cosmetics ingredients functions: Antimicrobial; preservative
InChI: 1S/C8H10O2/c9-6-7-10-8-4-2-1-3-5-8/h1-5,9H,6-7H2
InChIKey: QCDWFXQBSFUVSP-UHFFFAOYSA-N
SMILES: OCCOc1ccccc1
LogP: 1.2 at 23 °C

Dowanol EPH Glycol Ether is a commercial aromatic glycol ether solvent marketed by Dow, chemically identified as 2-phenoxyethanol.
Dowanol EPH Glycol Ether combines an aromatic phenyl group with an ethylene glycol ether moiety, giving the molecular formula C₈H₁₀O₂.
This structure provides strong organic solvency together with partial water compatibility.

From a structural and chemical perspective, Dowanol EPH Glycol Ether belongs to the phenyl ether subclass of glycol ethers.
The phenyl ring contributes high solvency for resins, oils, and hydrophobic materials, while the hydroxyl-containing ether chain enables interaction with polar components.
This dual character makes it an effective coupling solvent in complex formulations.

Physical properties of Dowanol EPH Glycol Ether include a relatively high boiling point, low vapor pressure, and moderate viscosity.
These features reduce evaporation losses, odor intensity, and worker exposure compared with lighter solvents.
It is stable under normal storage and processing conditions and does not readily degrade.

Solubility behavior is a key advantage of Dowanol EPH Glycol Ether.
It is miscible with many organic solvents and partially miscible with water, allowing it to bridge aqueous and solvent-based systems.
This property is especially valuable in water-borne coatings and emulsified formulations.

In coatings and surface technology, Dowanol EPH Glycol Ether is used as a solvent and coalescing aid.
It promotes polymer particle fusion during drying, improving film continuity, adhesion, and gloss.
Its controlled evaporation rate helps prevent defects such as cracking, pinholing, and poor leveling.

In inks, pigments, and printing systems, Dowanol EPH Glycol Ether enhances pigment wetting and dispersion.
It contributes to consistent viscosity and controlled drying behavior.
This results in improved color strength, print quality, and surface uniformity.

In adhesives, sealants, and polymer formulations, Dowanol EPH Glycol Ether functions as a compatibility solvent.
It dissolves binders, tackifiers, and plasticizers while maintaining homogeneous mixtures.
This improves shelf stability, application consistency, and final mechanical performance.

In personal care and cosmetic applications, Dowanol EPH Glycol Ether (as phenoxyethanol) is widely used as a preservative solvent and stabilizer.
It supports antimicrobial systems by solubilizing preservatives and fragrances evenly.
Typical applications include creams, lotions, wipes, deodorants, sunscreens, and hair-care products.

In household, institutional, and industrial cleaning products, Dowanol EPH Glycol Ether improves wetting, penetration, and soil removal.
It enhances the effectiveness of disinfectants and sanitizers by improving contact with surfaces and microorganisms.
Its low volatility makes it suitable for spray cleaners and wipes.

Dowanol EPH Glycol Ether helps dissolve resins, plasticizers, and functional additives without causing phase separation.
This improves shelf stability and application consistency.

In personal care and cosmetic formulations, Dowanol EPH Glycol Ether (as phenoxyethanol) is commonly used as a preservative solvent and antimicrobial support agent.
Dowanol EPH Glycol Ether solubilizes fragrances, preservatives, and active ingredients while maintaining clarity and texture.
Typical products include creams, lotions, wipes, deodorants, and hair-care formulations.

In household, institutional, and industrial cleaning products, Dowanol EPH Glycol Ether enhances the performance of disinfectants and detergents.
Dowanol EPH Glycol Ether improves wetting, penetration, and dissolution of soils and microorganisms.
This makes it valuable in hard-surface cleaners, sanitizers, and medical-grade wipes.

Pharmaceutical and medical relevance includes use as a formulation aid and preservative component in topical and non-injectable products.
Dowanol EPH Glycol Ether is also used in medical device cleaning and disinfection systems.
Such applications are strictly controlled to meet pharmacopoeial standards.

Toxicological characteristics indicate low acute toxicity when used within regulated limits.
However, concentrated exposure may cause skin or eye irritation, and ingestion or prolonged exposure is not recommended.
Occupational handling typically requires gloves, eye protection, and adequate ventilation.

Uses Of Dowanol EPH Glycol Ether:
Dowanol EPH Glycol Ether is widely used as a solvent and coalescing agent in water-borne and hybrid coatings.
Dowanol EPH Glycol Ether improves polymer particle coalescence during drying, resulting in uniform films with enhanced gloss, adhesion, and durability.
These properties make it suitable for architectural paints, industrial coatings, and protective surface finishes.

In industrial and decorative paint formulations, Dowanol EPH Glycol Ether helps control viscosity, flow, and leveling.
Dowanol EPH Glycol Ether reduces surface defects such as pinholes, poor adhesion, and uneven film thickness.
Its low volatility allows extended open time and smoother application.

Dowanol EPH Glycol Ether is commonly applied in printing inks and pigment dispersions.
It enhances pigment wetting and dispersion while stabilizing ink systems.
This leads to consistent color development and controlled drying behavior.

In adhesives, sealants, and resin systems, Dowanol EPH Glycol Ether functions as a compatibility and solvency agent.
It dissolves binders, tackifiers, and plasticizers while maintaining homogeneous formulations.
This improves shelf stability, application consistency, and bonding performance.

In personal care and cosmetic products, Dowanol EPH Glycol Ether (as phenoxyethanol) is used as a preservative solvent and formulation stabilizer.
It helps solubilize fragrances, preservatives, and active ingredients.
Typical products include creams, lotions, wipes, deodorants, sunscreens, and hair-care formulations.

Dowanol EPH Glycol Ether is used in household, institutional, and industrial cleaning products.
It improves wetting, penetration, and antimicrobial effectiveness of detergents and disinfectants.
Its low vapor pressure makes it especially suitable for spray cleaners and sanitizing wipes.

In pharmaceutical and medical-related formulations, Dowanol EPH Glycol Ether serves as a solvent and preservative-support ingredient in topical and non-injectable products.
It is also used in medical-grade cleaning and disinfection solutions.
Such uses require compliance with pharmacopoeial purity standards.

Dowanol EPH Glycol Ether is applied in agrochemical and specialty chemical formulations as a carrier and solubilizing agent.
It enhances dispersion and stability of active ingredients in liquid concentrates and emulsions.
This improves delivery efficiency and formulation reliability.

In industrial processing and surface treatment applications, Dowanol EPH Glycol Ether is used in metalworking fluids, surface cleaners, and specialty formulations.
It provides controlled solvency with reduced volatility and odor.
These characteristics support safer handling and consistent industrial performance.

Dowanol EPH Glycol Ether is extensively used as a high-performance coalescing solvent in water-borne coatings, where it enhances polymer film formation during drying.
It promotes particle fusion in latex systems, resulting in improved mechanical strength, gloss, and surface uniformity.
This makes it especially valuable in architectural, industrial, and protective coatings.

In high-solids and low-VOC formulations, Dowanol EPH Glycol Ether helps maintain performance while reducing overall solvent content.
Its strong solvency allows formulators to achieve effective resin dissolution at lower concentrations.
This supports compliance with environmental and regulatory VOC limits.

Dowanol EPH Glycol Ether is widely used in industrial maintenance coatings and corrosion-protection systems.
It improves adhesion to metal substrates and supports uniform film build.
These properties are important in structural steel, machinery, and equipment coatings.

In wood coatings and furniture finishes, Dowanol EPH Glycol Ether contributes to smooth film leveling and improved clarity.
It enhances compatibility with alkyd, acrylic, and polyurethane resin systems.
This leads to better surface appearance and durability.

In automotive refinishing and specialty coatings, Dowanol EPH Glycol Ether assists in pigment dispersion and viscosity control.
It helps achieve consistent spray application and controlled drying profiles.
This ensures high-quality surface finishes.

In specialty ink systems, including industrial marking and packaging inks, Dowanol EPH Glycol Ether improves pigment wetting and binder compatibility.
Dowanol EPH Glycol Ether supports controlled evaporation to optimize print definition and adhesion.
These characteristics are essential in high-performance printing applications.

Uses Of Dowanol EPH Glycol Ether:
Dowanol EPH Glycol Ether is extensively used as a high-performance coalescing solvent in water-borne coatings, where it enhances polymer film formation during drying.
It promotes particle fusion in latex systems, resulting in improved mechanical strength, gloss, and surface uniformity.
This makes it especially valuable in architectural, industrial, and protective coatings.

In specialty ink systems, including industrial marking and packaging inks, Dowanol EPH Glycol Ether improves pigment wetting and binder compatibility.
It supports controlled evaporation to optimize print definition and adhesion.
These characteristics are essential in high-performance printing applications.

In cosmetic and dermatological formulations, Dowanol EPH Glycol Ether (phenoxyethanol) functions as both a preservative solvent and stabilizer.
It enhances antimicrobial protection by dissolving preservative blends uniformly throughout the product.
Its use is common in lotions, creams, serums, wipes, and liquid formulations.

In antimicrobial and disinfectant products, Dowanol EPH Glycol Ether improves solubility and penetration of active agents.
It increases surface wetting and contact efficiency, enhancing cleaning and sanitizing performance.
This makes it useful in institutional, healthcare, and industrial hygiene products.

In agrochemical formulations, Dowanol EPH Glycol Ether serves as a solvent and carrier for herbicides, fungicides, and insecticides.
Dowanol EPH Glycol Ether improves dispersion stability and ensures uniform delivery of active ingredients.
This supports consistent application and product effectiveness.

In specialty chemical manufacturing, Dowanol EPH Glycol Ether is used as a processing solvent and intermediate carrier.
Dowanol EPH Glycol Ether supports dissolution, blending, and stabilization of formulation components.
Its low volatility and broad compatibility make it suitable for controlled industrial processes.

Dowanol EPH Glycol Ether also appears in medical-grade cleaning and disinfection solutions for equipment and devices.
Such uses require compliance with pharmacopoeial purity standards.

Dowanol EPH Glycol Ether is applied in agricultural and specialty chemical formulations as a carrier and solubilizing agent.
It helps disperse active ingredients evenly in sprayable or emulsified products.
This improves formulation stability and delivery efficiency.

In industrial processing and manufacturing, Dowanol EPH Glycol Ether is used in metalworking fluids, surface treatments, and specialty formulations.
Dowanol EPH Glycol Ether provides controlled solvency without excessive evaporation.
These properties support safer handling and consistent process performance.

Dowanol EPH Glycol Ether is a preservative used in consumer and health care products, including vaccines, pen inks, ear drops, shampoos, skin cleansers, moisturizers, sun care products, and topical medicaments.
The preservative Euxyl-K 400 also contains Dowanol EPH Glycol Ether, in combination with methyldibromoglutaronitrile.
Dowanol EPH Glycol Ether is commonly used in cosmetics for its antibacterial and antifungal properties.

Safety Profile Of Dowanol EPH Glycol Ether:
Dowanol EPH Glycol Ether (2-phenoxyethanol) can cause skin and eye irritation upon direct contact, especially at high concentrations or with prolonged exposure.
Symptoms may include redness, itching, or a burning sensation.
Protective gloves and eye protection are recommended during handling.

Inhalation exposure to vapors or mists may cause respiratory irritation and mild central nervous system effects.
Reported symptoms include headache, dizziness, nausea, and fatigue, particularly in poorly ventilated areas.
Although its vapor pressure is relatively low, adequate ventilation is required in industrial settings.

Ingestion hazards involve gastrointestinal irritation and systemic toxicity if swallowed in significant amounts.
Toxicological studies indicate potential effects on the liver, kidneys, and nervous system at high doses.
Accidental ingestion should be treated as a medical emergency.

Chronic or repeated exposure at elevated levels may pose additional health risks.
Prolonged exposure has been associated with neurological effects and blood chemistry changes in experimental studies.
For this reason, regulatory bodies set strict concentration limits in cosmetics, pharmaceuticals, and occupational environments.

Dowanol EPH Glycol Ether is combustible, though not highly flammable under normal conditions.
At elevated temperatures, it may form flammable vapor–air mixtures.
Thermal decomposition can produce hazardous gases such as carbon monoxide and aromatic compounds.