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CAS NO:120-47-8
EC NO:204-399-4
E 214 (Ethyl p-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid.
E 214 (Ethyl p-hydroxybenzoate)s formula is HO-C6H4-CO-O-CH2CH3.
E 214 (Ethyl p-hydroxybenzoate) is a member of the class of compounds known as parabens.
E 214 (Ethyl p-hydroxybenzoate) is used as an antifungal preservative. As a food additive, it has E number E214.
E 214 (Ethyl p-hydroxybenzoate), the sodium salt of ethylparaben, has the same uses and is given the E number E215.
Properties:
Chemical formula: C9H10O3
Molar mass: 166.176 g·mol−1
Melting point: 115 to 118 °C (239 to 244 °F; 388 to 391 K)
Boiling point: 297 to 298 °C (567 to 568 °F; 570 to 571 K)
E 214 (Ethyl p-hydroxybenzoate) is an ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol,
E 214 (Ethyl p-hydroxybenzoate) has a role as an antimicrobial food preservative, an antifungal agent, a plant metabolite and a phytoestrogen.
E 214 (Ethyl p-hydroxybenzoate) is a paraben and an ethyl ester.
E 214 (Ethyl p-hydroxybenzoate) is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
E 214 (Ethyl p-hydroxybenzoate) is a natural product found in Ulva australis, Andrographis paniculata, and other organisms with data available.
E 214 (Ethyl p-hydroxybenzoate) is used as a preservative and food additive and is found in food and cosmetic products.
Uses
-Cleansers
-Cosmetics
-Hair Dyes
-Liquids/Creams
-Shampoos/Conditioners
E 214 (Ethyl p-hydroxybenzoate) was used to study the in-situ derivatisation solid-phase microextraction procedure for determining parabens, related chlorophenols, and triclosan in water.
E 214 (Ethyl p-hydroxybenzoate), a novel sorbent for solid-phase extraction, was used to study its retention property.
E 214 (Ethyl p-hydroxybenzoate) has high extraction efficiency towards the compounds tested owing to the electrostatic interaction, hydrophobic interaction and hydrogen bonding.
E 214 (Ethyl p-hydroxybenzoate) USP is in the paraben family of preservatives used by the food, pharmaceutical, and personal care product industries.
E 214 (Ethyl p-hydroxybenzoate) is highly effective in preventing the growth of fungi and bacteria and can be used to preserve products and greatly extend their shelf life.
E 214 (Ethyl p-hydroxybenzoate) appears as a white crystalline powder.
Physicochemical Information:
Boiling point: 297 °C (free ester),(decomposition)
Flash point: 121 °C
Melting Point: >115 °C (free ester)
pH value: 10 (1 g/l, H₂O, 20 °C)
Bulk density: 600 kg/m3
Solubility: 1000 g/l
E 214 (Ethyl p-hydroxybenzoate), also called ethylparaben is the ethyl ester of p-hydroxybenzoic acid.
E 214 (Ethyl p-hydroxybenzoate)s formula is HO-C6H4-CO-O-CH2CH3.
E 214 (Ethyl p-hydroxybenzoate) is used as a preservative. As a food additive, it has E number E214.
E 214 (Ethyl p-hydroxybenzoate) is used in studying the effect of tobacco ingredients (flavorings and additives) on smoke chemistry.
E 214 (Ethyl p-hydroxybenzoate) is also a useful reagent in synthesis of Poly(bis(4-carboxyphenoxy)phosphazene).
E 214 (Ethyl p-hydroxybenzoate) belongs to the class of organic compounds known as p-hydroxybenzoic acid alkyl esters. These are aromatic compounds containing a benzoic acid, which is esterified with an alkyl group and para-substituted with a hydroxyl group.
E 214 (Ethyl p-hydroxybenzoate) is used as an antifungal preservative. Sodium ethyl para-hydroxybenzoate, the sodium salt of ethylparaben, has the same uses and is given the E number E215.
E 214 (Ethyl p-hydroxybenzoate) is a drug.
E 214 (Ethyl p-hydroxybenzoate)s formula is HO-C6H4-CO-O-CH2CH3.
E 214 (Ethyl p-hydroxybenzoate) is a mild and phenolic tasting compound.
E 214 (Ethyl p-hydroxybenzoate) has been detected, but not quantified, in alcoholic beverages. This could make ethylparaben a potential biomarker for the consumption of these foods.
E 214 (Ethyl p-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid.
E 214 (Ethyl p-hydroxybenzoate) is a potentially toxic compound. As a food additive, it has E number E214.
About E 214 (Ethyl p-hydroxybenzoate)
Helpful information
E 214 (Ethyl p-hydroxybenzoate) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
E 214 (Ethyl p-hydroxybenzoate) is used by consumers, by professional workers (widespread uses), in formulation or re-packing and at industrial sites.
Consumer Uses
E 214 (Ethyl p-hydroxybenzoate) is used in the following products: cosmetics and personal care products and perfumes and fragrances.
Other release to the environment of E 214 (Ethyl p-hydroxybenzoate) is likely to occur from: indoor use as processing aid.
Article service life
ECHA has no public registered data on the routes by which E 214 (Ethyl p-hydroxybenzoate) is most likely to be released to the environment. ECHA has no public registered data indicating whether or into which articles the substance might have been processed.
Widespread uses by professional workers
E 214 (Ethyl p-hydroxybenzoate) is used in the following products: cosmetics and personal care products.
ECHA has no public registered data on the types of manufacture using E 214 (Ethyl p-hydroxybenzoate). Other release to the environment of E 214 (Ethyl p-hydroxybenzoate) is likely to occur from: indoor use as processing aid.
Formulation or re-packing
E 214 (Ethyl p-hydroxybenzoate) is used in the following products: cosmetics and personal care products, pharmaceuticals and perfumes and fragrances.
Release to the environment of E 214 (Ethyl p-hydroxybenzoate) can occur from industrial use: formulation of mixtures.
Uses at industrial sites
E 214 (Ethyl p-hydroxybenzoate) is used in the following products: laboratory chemicals and pharmaceuticals.
E 214 (Ethyl p-hydroxybenzoate) is used for the manufacture of: chemicals.
Release to the environment of E 214 (Ethyl p-hydroxybenzoate) can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates).
Manufacture
ECHA has no public registered data on the routes by which E 214 (Ethyl p-hydroxybenzoate) is most likely to be released to the environment.
Chemical Properties
Ethylparaben occurs as a white, odorless or almost odorless, crystalline powder.
Uses
E 214 (Ethyl p-hydroxybenzoate) is mainly used as antiseptics in cosmetics, food and medicine.
E 214 (Ethyl p-hydroxybenzoate) is also can be used as feed preservatives and antiseptic for bacteria.
E 214 (Ethyl p-hydroxybenzoate) is a preservative that is used in the formulation of cosmetics and personal care products in order to extend the shelf-life by preventing microbial contamination. In most formulations, parabens are used at very low levels ranging from 0.01 to 0.3%.
E 214 (Ethyl p-hydroxybenzoate), a novel sorbent for solid-phase extraction, was used to study its retention property.
E 214 (Ethyl p-hydroxybenzoate) has high extraction efficiency towards the compounds tested owing to the electrostatic interaction, hydrophobic interaction and hydrogen bonding.
Definition
ChEBI:
E 214 (Ethyl p-hydroxybenzoate) is an ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol.
E 214 (Ethyl p-hydroxybenzoate) has a role as an antimicrobial food preservative, an antifungal agent, a plant metabolite and a phytoestrogen.
E 214 (Ethyl p-hydroxybenzoate) is a paraben and an ethyl ester.
Production Methods
E 214 (Ethyl p-hydroxybenzoate) is prepared by the esterification of p-hydroxybenzoic acid with ethanol (95%).
Pharmaceutical Applications
E 214 (Ethyl p-hydroxybenzoate) is widely used as an antimicrobial preservative in cosmetics,food products, and pharmaceutical formulations.
E 214 (Ethyl p-hydroxybenzoate) may be used either alone or in combination with other paraben esters or with other antimicrobial agents. In cosmetics it is one of the most frequently used preservatives.
The parabens are effective over a wide pH range and have a broad spectrum of antimicrobial activity, although they are most effective against yeasts and molds.
Owing to the poor solubility of the parabens, paraben salts, particularly the sodium salt, are frequently used. However, this may cause the pH of poorly buffered formulations to become more alkaline.
E 214 (Ethyl p-hydroxybenzoate) is a water-soluble preservative, the main features are safe, efficient, broad-spectrum antibacterial. Widely used in the pharmaceutical industry (Chinese herbal medicine, pharmaceutical preparation; Medical equipment Disinfection); Food industry (dairy products, pickled products, beverages, fruit juices, jelly, cakes, etc.); Textile industry (textiles, cotton yarn, chemical fiber) anti-corrosion. As well as other such as cosmetics, feed, daily Industrial anti-corrosion. 20kg carton, composite aluminum film bag.
E 214 (Ethyl p-hydroxybenzoate) was used to study the in-situderivatisation solid-phase microextraction procedure for determining parabens, related chlorophenols and triclosan in water.
E 214 (Ethyl p-hydroxybenzoate) is a novel sorbent for solid-phase extraction, was used to study its retention property.
E 214 (Ethyl p-hydroxybenzoate) has high extraction efficiency towards the compounds tested owing to the electrostatic interaction, hydrophobic interaction and hydrogen bonding.
Technical Information
Appearance :Crystalline
Physical State :Solid
Storage :Store at 4° C
Melting Point :105-107° C
E 214 (Ethyl p-hydroxybenzoate) is one of the commonly used preservatives.
E 214 (Ethyl p-hydroxybenzoate) can inhibit the activity of the respiratory enzyme system and the transmission enzyme system of microbial cells, and destroy the cell membrane mechanism of microorganisms, which has a wide range of antibacterial effects on mold, yeast and bacteria.
E 214 (Ethyl p-hydroxybenzoate) antibacterial ability is stronger than sorbic acid and benzoic acid, and the antibacterial effect is not affected by pH value, and the effect is good in the range of pH value 4~8.
IUPAC names:
Benzoic acid, 4-hydroxy-, ethyl ester
Ethyl 4-Hydroxybenzoate
Ethyl 4-hydroxybenzoate
ethyl 4-hydroxybenzoate
Ethyl 4-hydroxybenzoate
ethyl 4-hydroxybenzoate
Ethyl p-hydroxybenzoate
ETHYL PARABEN
EThyl-4-hydroxybenzoate
Ethylparaben
SYNONYMS:
Sodium ethyl p-hydroxybenzoate
252-487-6 [EINECS]
35285-68-8 [RN]
4-(Éthoxycarbonyl)phénolate de sodium [French] [ACD/IUPAC Name]
Benzoic acid, 4-hydroxy-, ethyl ester, sodium salt (1:1) [ACD/Index Name]
E215
ETHYLPARABEN SODIUM
Natrium-4-(ethoxycarbonyl)phenolat [German] [ACD/IUPAC Name]
p-hydroxybenzoic acid ethyl ester sodium salt
Sodium 4-(ethoxycarbonyl)phenolate [ACD/IUPAC Name]
Sodium ethylparaben
Z0D00IVA10
[35285-68-8] [RN]
4-ethoxycarbonylphenolate
4-Hydroxybenzoic acid, ethyl ester, sodium salt
4-Hydroxybenzoic acid-ethyl ester sodium
5026-62-0 [RN]
Benzoic acid, 4-hydroxy-, ethyl ester, sodium salt
Benzoic acid, 4-hydroxy-, methyl ester, sodium salt
Bonomold OMNa
EINECS 225-714-1
EINECS 252-487-6
Ethyl p-hydroxybenzoate, sodium salt
ETHYL4-HYDROXYBENZOATESODIUMSALT
Ethylparaben sodium salt
Ethylparaben, sodium salt
Methyl 4-hydroxybenzoate sodium salt
METHYL P-HYDROXYBENZOATE, SODIUM SALT
Methylparaben sodium [NF]
Methylparaben sodium (NF)
Methylparaben sodium [USAN] [USAN]
methylparaben, sodium salt
MFCD00016475 [MDL number]
NIPASEPT SODIUM
Preserval MS
Sodium [ACD/Index Name] [ACD/IUPAC Name] [Wiki]
sodium 4-(ethoxycarbonyl)benzen-1-olate
SODIUM 4-(ETHOXYCARBONYL)BENZENOLATE
Sodium 4-(methoxycarbonyl)phenolate [ACD/IUPAC Name]
sodium 4-carbethoxyphenolate
sodium 4-carbomethoxyphenolate
sodium 4-ethoxycarbonylphenolate
