E357 POTASSIUM ADIPATE

E357 Potassium adipate is a synthetic potassium salt of adipic acid primarily used as a food additive. 
E357 Potassium adipate functions as an acidity regulator, flavor enhancer, and leavening agent, commonly found in desserts, baking powders, and fruit drinks. 
E357 Potassium adipate is the potassium salt of adipic acid, a synthetic organic compound derived from hexanedioic acid, and it is mainly used as an acidity regulator, buffering agent, and preservative-supporting stabilizer in food and industrial applications because it helps control pH and improve stability of formulations while also supporting preservation systems by making conditions less favorable for microbial growth.

CAS Number: 19147-16-1
Molecular Formula: C6H8K2O4
Molecular Weight: 222.32
EINECS Number: 242-838-1

Synonyms: Potassium adipate, Dipotassium adipate, Dipotassium Hexanedioate, UNII-493TD6PDYS, Hexanedioic acid, dipotassium salt, 493TD6PDYS, EINECS 242-838-1, EC 242-838-1, Hexanedioic acid, potassium salt (1:2), INS NO.357, DTXSID60894861, INS-357, POTASSIUM ADIPATE [WHO-DD], ADIPIC ACID, DIPOTASSIUM SALT, J125.426J, E-357, RefChem:175409, DTXCID201324423, 19147-16-1, dipotassium;hexanedioate, Kaliumadipat, dipotassium,hexanedioate, SCHEMBL106750, NS00078209, Q931445, DIPOTASSIUM ADIPATE;Kaliumadipat;Potassiumadipate;Adipic acid dipotassium salt

E357 Potassium adipate is closely related to other adipates such as sodium adipate.
This improves pH control and product stability.
E357 Potassium adipate consists of an adipic acid backbone (a six-carbon dicarboxylic acid) neutralized with potassium ions, which makes it highly water-soluble and effective in buffering systems that resist sudden changes in acidity.

E357 Potassium adipates structure allows it to interact with hydrogen ions and maintain stable pH conditions.
This improves buffering capacity and chemical stability.
Physically, it appears as a white crystalline powder or granular solid, and it dissolves easily in water to form neutral to mildly alkaline solutions depending on concentration, making it suitable for liquid and solid formulations.

E357 Potassium adipate is generally stable under normal storage conditions and non-volatile.
E357 Potassium adipate improves handling and formulation convenience.
E357 Potassium adipate acts mainly as a pH stabilizer and acidity regulator, helping maintain consistent acidity levels in products, which is important for flavor balance, microbial stability, and chemical integrity during storage and processing.

E357 Potassium adipate also helps reduce unwanted reactions that could degrade product quality over time.
This improves shelf life and product consistency.
E357 Potassium adipate is best described as a water-soluble potassium salt of adipic acid used to regulate acidity, stabilize formulations, and support preservation systems in food, pharmaceutical, cosmetic, and industrial applications through buffering and pH control.

E357 Potassium adipate is also used in advanced pH engineering systems, where very small changes in acidity can strongly affect product stability, because adipate-based buffers provide a relatively “flat” buffering range that helps keep formulations chemically steady during heating, cooling, or long storage periods.
This makes it useful in products that must remain stable across different environmental conditions.
E357 Potassium adipate improves formulation robustness and long-term stability.

E357 Potassium adipate is often used as part of a multi-additive system rather than alone, where it works together with other acidity regulators and preservatives to create a combined effect that slows microbial growth and reduces spoilage risk without strongly affecting taste.
This synergistic approach is common in modern processed foods.
E357 Potassium adipate improves preservation efficiency and food safety.

In beverage formulation design, E357 Potassium adipate is useful when manufacturers want to avoid strong sourness but still need precise acidity control, because adipate salts provide pH adjustment with minimal sensory impact compared to more aggressive acids like citric or lactic acid.
This helps maintain a clean, neutral taste profile.
E357 Potassium adipate improves flavor neutrality and formulation precision.

In protein and dairy-like systems, E357 Potassium adipate can help stabilize emulsions and prevent unwanted separation by maintaining a consistent ionic environment, which reduces the risk of curdling or phase separation in sensitive liquid products.
This is especially useful in plant-based dairy alternatives.
E357 Potassium adipate improves texture stability and emulsion integrity.

E357 Potassium adipate supports chemical stability of active ingredients by preventing pH drift over time, which is critical because many drug molecules degrade faster when acidity is not controlled precisely.
It also helps maintain compatibility between multiple dissolved excipients.
E357 Potassium adipate improves drug shelf life and formulation reliability.

In cosmetic emulsions and gels, E357 Potassium adipate plays a supporting role in maintaining stable pH conditions that protect preservatives and active ingredients, ensuring that antimicrobial systems remain effective throughout the product’s shelf life.
It also helps reduce degradation of fragrance and botanical compounds.
E357 Potassium adipate improves cosmetic preservation and ingredient stability.

In industrial detergent systems, E357 Potassium adipate helps stabilize cleaning formulations in different water conditions by buffering against pH fluctuations caused by dissolved minerals or contamination, ensuring more consistent cleaning performance.
It is particularly useful in automated cleaning systems.
E357 Potassium adipate improves detergent reliability and performance consistency.

In chemical manufacturing processes, E357 Potassium adipate can be used to maintain controlled reaction environments where adipate-based intermediates are involved, helping prevent unwanted side reactions caused by pH instability.
Its predictable buffering behavior supports process optimization.
E357 Potassium adipate improves chemical process control and yield stability.

In biodegradability and green chemistry development, adipate compounds are studied because they can break down under environmental or microbial conditions, making them candidates for more sustainable chemical systems compared to persistent synthetic additives.
This supports efforts to design greener industrial materials.
E357 Potassium adipate improves environmental sustainability and biodegradation potential.

E357 Potassium adipate can indirectly support polymer and resin systems by maintaining stable aqueous environments during synthesis or processing, even though it is not a primary structural polymer component itself.
Its role is mainly functional rather than structural.
E357 Potassium adipate improves process stability and formulation control.

Density: 0.72[at 20℃]
vapor pressure: 9.7Pa at 20℃
Water Solubility: 1000g/L at 20℃
LogP: -4.2 at 20℃

E357 Potassium adipate is used in food processing systems where maintaining stable acidity is important for preventing spoilage, controlling flavor, and ensuring consistent product quality, especially in processed foods that undergo long storage or temperature changes.
Its buffering properties help keep the chemical environment stable even under varying conditions.
E357 Potassium adipate improves food safety and shelf stability.

E357 Potassium adipate helps maintain pH stability and prevents unwanted changes in taste or appearance caused by fluctuations in acidity during storage or transport.
It also supports clarity by reducing conditions that may promote precipitation of dissolved components.
E357 Potassium adipate improves beverage consistency and visual quality.

E357 Potassium adipate can work alongside other preservatives and acidity regulators to create conditions that inhibit microbial growth, especially in products that require extended shelf life without refrigeration.
It is often used in combination systems rather than alone.
E357 Potassium adipate improves preservation efficiency and product longevity.

In pharmaceutical formulations, E357 Potassium adipate can function as a buffering agent in liquid dosage forms, helping maintain stable pH levels that protect active pharmaceutical ingredients from degradation or reduced effectiveness.
It also improves compatibility between different formulation components.
E357 Potassium adipate improves drug stability and formulation reliability.

In cosmetic and personal care products, E357 Potassium adipate is used to stabilize pH in creams, gels, and liquid formulations, helping maintain product integrity and supporting preservative systems that require a specific pH range to remain effective.
It helps prevent breakdown of sensitive ingredients.
E357 Potassium adipate improves cosmetic stability and shelf life.

In industrial cleaning systems, E357 Potassium adipate can contribute to pH control and stabilization of cleaning formulations, helping improve performance in removing residues while reducing unwanted corrosion or instability in the product mixture.
It supports consistent cleaning behavior across different water conditions.
E357 Potassium adipate improves cleaning efficiency and formulation control.

E357 Potassium adipate is used as a mild buffering agent to stabilize reaction environments where adipate chemistry is involved, helping control acidity-sensitive processes in industrial synthesis.
Its water solubility makes it easy to integrate into aqueous systems.
E357 Potassium adipate improves process stability and chemical control.

In environmental and biodegradability research, adipate compounds are studied because they can be broken down by microorganisms under certain conditions, making them relevant in discussions about more sustainable alternatives to persistent synthetic additives.
This makes them interesting in green chemistry development.
E357 Potassium adipate improves environmental compatibility and sustainability potential.

In food technology formulation design, E357 Potassium adipate is often selected when a neutral taste impact is required, since it does not strongly alter flavor compared with more acidic additives like citric acid.
This allows better control of taste profiles in delicate formulations.
E357 Potassium adipate improves sensory neutrality and product design flexibility.

In storage stability engineering, E357 Potassium adipate helps reduce degradation reactions triggered by pH fluctuations, such as oxidation or hydrolysis of sensitive ingredients, thereby improving long-term product reliability in packaged goods.
This is especially important for long shelf-life products.

E357 Potassium adipate improves durability and formulation robustness.
E357 Potassium adipate is a compound with formula K2C6H8O4. It is a potassium salt and common source ingredient of adipic acid.[1]

Uses Of E357 Potassium adipate:
E357 Potassium adipate is mainly used as an acidity regulator, buffering agent, and stabilizer because it helps maintain stable pH conditions and supports product preservation and consistency.
In food and beverages, it is used to control acidity and improve shelf stability.
This improves product safety and quality.

E357 Potassium adipate is used to support preservation systems and prevent spoilage.
This improves shelf life and storage stability.
In pharmaceuticals, it is used as a buffering agent in liquid formulations.

This improves drug stability and effectiveness.
In cosmetics, it is used to stabilize pH and protect sensitive ingredients.
E357 Potassium adipate improves product longevity and performance.

In industrial formulations, it is used for pH control and system stabilization.
This improves process reliability and consistency.
E357 Potassium adipate is mainly used as an acidity regulator, buffering agent, and stabilizer because it maintains stable pH conditions and supports preservation and formulation consistency.

In food and beverages, it is used to control acidity with minimal taste impact.
E357 Potassium adipate improves flavor balance and product stability.
In processed foods, it is used to support preservation systems and reduce spoilage.

E357 Potassium adipate improves shelf life and safety.
In pharmaceuticals, it is used as a buffering agent in liquid formulations.
E357 Potassium adipate improves drug stability and effectiveness.

In cosmetics, it is used to stabilize pH and protect sensitive ingredients.
This improves product longevity and performance.

In industrial systems, E357 Potassium adipate is used for pH control and formulation stabilization.
This improves process reliability and consistency.
E357 Potassium adipate is mainly used as an acidity regulator, buffering agent, and stabilizer because it helps maintain a stable pH environment, reduces unwanted chemical changes, and supports the preservation and consistency of formulations in food and industrial systems.

E357 Potassium adipate is used to control acidity while having a very mild sensory impact, which helps keep the original taste profile of the product unchanged while still improving stability during storage.
This improves flavor neutrality and shelf life.
In processed and packaged foods, it is used as part of preservation systems to reduce spoilage risk by maintaining conditions that are less favorable for microbial growth and unwanted chemical reactions.

E357 Potassium adipate improves product safety and storage stability.
In pharmaceutical formulations, it is used as a buffering agent in liquid medicines to maintain a stable pH, which is important for protecting active ingredients from degradation over time.
This improves drug stability and effectiveness.

In cosmetics and personal care products, it is used to stabilize pH in creams, lotions, gels, and liquid products, helping preserve the effectiveness of active ingredients and preservative systems.
E357 Potassium adipate improves product shelf life and formulation reliability.
In industrial cleaning systems, it is used to support pH control and improve the performance of cleaning agents in different water conditions by maintaining stable chemical behavior.

E357 Potassium adipate improves cleaning efficiency and consistency.
In chemical and formulation processes, it is used as a stabilizing buffer in aqueous systems where maintaining controlled acidity is important for product quality and reaction stability.
E357 Potassium adipate improves process control and formulation reliability.

E357 Potassium adipate is mainly used as an acidity regulator, buffering agent, and stabilizer because it helps maintain a consistent pH level, reduces unwanted chemical reactions, and improves the overall stability and shelf life of formulated products across food, pharmaceutical, cosmetic, and industrial systems.
In food and beverage products, it is used to control acidity in a very mild and almost taste-neutral way, which is useful when manufacturers want to maintain the original flavor profile without adding strong sourness or noticeable aftertaste.
E357 Potassium adipate improves flavor stability and product consistency during storage.

In processed and packaged foods, it is used as part of multi-component preservation systems where it helps create a stable pH environment that slows down spoilage reactions and reduces conditions favorable to microbial growth.
This improves shelf life and food safety.
In pharmaceutical liquid formulations, it is used as a buffering agent to keep pH within a narrow and stable range, which is important for protecting sensitive active pharmaceutical ingredients from hydrolysis or degradation.

E357 Potassium adipate improves drug stability and formulation reliability.
In cosmetic and skincare products, it is used to stabilize pH in emulsions, gels, and lotions, ensuring that active ingredients such as vitamins, botanical extracts, and preservatives remain effective over time.
This improves product performance and shelf life.

In industrial cleaning formulations, it is used to support pH control in detergent systems, helping maintain consistent cleaning performance even when water hardness or contamination varies.
E357 Potassium adipate improves cleaning efficiency and product stability.
In chemical processing and manufacturing systems, it is used as a buffering and stabilizing additive in aqueous environments where small pH changes could negatively affect reaction outcomes or product quality.

E357 Potassium adipate improves process reliability and chemical control.
In specialty formulation engineering, potassium adipate is used when a non-aggressive, low-taste-impact buffering system is required, especially in sensitive formulations where stronger acids or salts would interfere with stability or sensory properties.
E357 Potassium adipate improves formulation flexibility and product design precision.

Safety Profile Of E357 Potassium adipate:
E357 Potassium adipate is generally considered a low hazard substance, especially because it is a salt of a relatively stable organic acid, although concentrated exposure can still cause mild irritation in industrial settings.
The main hazard is mild irritation of skin, eyes, and respiratory tract, particularly from dust or concentrated solutions during handling.
Proper ventilation and protective equipment are recommended.

This improves workplace safety.
Skin contact is generally low risk, though prolonged exposure may cause mild irritation or dryness.
Washing with water is sufficient.

Eye contact may cause moderate irritation, especially from powder exposure.
Protective eyewear is recommended.
Inhalation of dust may cause temporary respiratory irritation, particularly in poorly ventilated environments.

Dust control measures are recommended.
E357 Potassium adipate is not flammable and is chemically stable under normal storage conditions.
This improves handling safety.

From a toxicological perspective, adipate salts are generally considered safe within regulated limits for food and industrial use due to their low reactivity and predictable metabolic breakdown pathways.
However, excessive exposure should still be avoided.
E357 Potassium adipate requires standard industrial hygiene practices.

From an environmental perspective, E357 Potassium adipate is considered relatively low risk and potentially biodegradable under suitable conditions, though large-scale discharge should still be managed responsibly.
E357 Potassium adipate improves environmental safety and sustainability.
E357 Potassium adipate is a low-toxicity buffering and acidity-regulating agent whose main hazards are mild irritation rather than chemical toxicity, making it suitable for regulated food, pharmaceutical, cosmetic, and industrial applications.