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CAS NUMBER: 9004-99-3
EC NUMBER: 244-754-0
MOLECULAR FORMULA: C20H40O3
MOLECULAR WEIGHT: 328.53
E431 (Polyoxyethylene (40) stearate) is a neutral surfactant.
E431 (Polyoxyethylene (40) stearate) is an ingredient used in cosmetics and beauty products primarily as a surfactant and emulsifier.
E431 (Polyoxyethylene (40) stearate) is a mixture of polyethylene glycol esters.
E431 (Polyoxyethylene (40) stearate) is compatible with lipophilic compounds due to a higher free fatty acid content.
E431 (Polyoxyethylene (40) stearate) are esters of polyethylene glycol and stearic acid.
E431 (Polyoxyethylene (40) stearate) are soft to waxy solids that are white to tan in color.
In cosmetics and personal care products, E431 (Polyoxyethylene (40) stearate) are used in skin creams, conditioners, shampoos, body cleansers and soapless detergents.
E431 (Polyoxyethylene (40) stearate) is used in cosmetics and beauty products primarily as a surfactant and cleansing agent, because PEG Stearates' ability to clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away.
E431 (Polyoxyethylene (40) stearate) is also seen as an emollient, because of secondary properties.
E431 (Polyoxyethylene (40) stearate) has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers.
E431 (Polyoxyethylene (40) stearate) has also been used in a study to investigate its effects on multidrug resistance (MDR).
E431 (Polyoxyethylene (40) stearate) is a non-ionic surfactant, which is permitted for use as the E number food additive E431.
E431 (Polyoxyethylene (40) stearate) is a high molecular weight, high HLB surface active agent suggested for use in cosmetic formulations.
E431 (Polyoxyethylene (40) stearate) is a multifunctional surface active agent suggested for use in cosmetic formulations, household products, lubricants, textile chemicals, polishes and paper.
E431 (Polyoxyethylene (40) stearate) is listed as particularly applicable for hand and body lotions and creams.
E431 (Polyoxyethylene (40) stearate) is an emulsifier and antifoaming agent used in processed foods, fruit jellies, and sauces.
E431 (Polyoxyethylene (40) stearate) is a mixture of the monoand diesters of stearic acid and mixed polyoxyethylene diols having an average polymer length.
E431 (Polyoxyethylene (40) stearate) corresponds to the average number of ethylene oxide monomers in the polyethylene chain (from 2 - 150).
E431 (Polyoxyethylene (40) stearate) is not considered to be an irritant or sensitizer (it gave only minimal irritation in studies up to 100%), and are CIR and FDA approved for use, but not on broken skin.
E431 (Polyoxyethylene (40) stearate) has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers.
E431 (Polyoxyethylene (40) stearate) has also been used in a study to investigate its effects on multidrug resistance (MDR).
E431 (Polyoxyethylene (40) stearate) belongs to the class of organic compounds known as fatty acid esters.
These are carboxylic ester derivatives of a fatty acid.
E431 (Polyoxyethylene (40) stearate) is considered to be a practically insoluble (in water) and relatively neutral molecule.
E431 (Polyoxyethylene (40) stearate) has been primarily detected in urine.
E431 (Polyoxyethylene (40) stearate) is primarily located in the membrane (predicted from logP) and cytoplasm.
E431 (Polyoxyethylene (40) stearate) were trimethylsilylated and injected onto a WCOT 50 m X 0.25 mm CP-SIL 5 CB fused silica column.
Characteristic profiles can be obtained from E431 (Polyoxyethylene (40) stearate) deriv carrying different functional groups.
E431 (Polyoxyethylene (40) stearate) is used in cosmetics and beauty products primarily as a surfactant and emulsifier.
E431 (Polyoxyethylene (40) stearate) occurs naturally as a white, waxy or flaky substance, according to The Food and Agriculture Organization of the United Nations.
E431 (Polyoxyethylene (40) stearate), as part of the PEG Stearate group, are formed from a naturally fatty acid known as Stearic Acid.
E431 (Polyoxyethylene (40) stearate) are used in cosmetics and skin care formulas because they can "clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away.
E431 (Polyoxyethylene (40) stearate) is also used as an excipient in many pharmaceutical products.
E431 (Polyoxyethylene (40) stearate) is the basis of a number of laxatives.
Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.
E431 (Polyoxyethylene (40) stearate) has also been used to preserve objects that have been salvaged from underwater, as was the case with the warship Vasa in Stockholm, and similar cases.
E431 (Polyoxyethylene (40) stearate) replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.
In addition, E431 (Polyoxyethylene (40) stearate) is used when working with green wood as a stabilizer, and to prevent shrinkage.
E431 (Polyoxyethylene (40) stearate) has been used to preserve the painted colors on unearthed at a UNESCO World Heritage site in China.
The paint would subsequently flake off in about four minutes.
E431 (Polyoxyethylene (40) stearate) is preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.
E431 (Polyoxyethylene (40) stearate) is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning.
E431 (Polyoxyethylene (40) stearate) derivatives, such as narrow range ethoxylates, are used as surfactants.
E431 (Polyoxyethylene (40) stearate) has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.
E431 (Polyoxyethylene (40) stearate) has also been used as a propellent.
E431 (Polyoxyethylene (40) stearate) is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.
E431 (Polyoxyethylene (40) stearate) is commonly used as a precipitant for plasmid DNA isolation and protein crystallization.
E431 (Polyoxyethylene (40) stearate) is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas.
E431 (Polyoxyethylene (40) stearate) precipitation is used to concentrate viruses.
E431 (Polyoxyethylene (40) stearate) is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro.
Gene therapy vectors (such as viruses) can be E431 (Polyoxyethylene (40) stearate)-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.
The size of the E431 (Polyoxyethylene (40) stearate) polymer has been shown to be important, with larger polymers achieving the best immune protection.
E431 (Polyoxyethylene (40) stearate) is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin).
E431 (Polyoxyethylene (40) stearate) is used in a number of toothpastes as a dispersant.
E431 (Polyoxyethylene (40) stearate) binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste.
E431 (Polyoxyethylene (40) stearate) is also under investigation for use in body armor, and in tattoos to monitor diabetes.
E431 (Polyoxyethylene (40) stearate) has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.
E431 (Polyoxyethylene (40) stearate) is also used as a polymer host for solid polymer electrolytes.
Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving E431 (Polyoxyethylene (40) stearate), with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future.
E431 (Polyoxyethylene (40) stearate) is injected into industrial processes to reduce foaming in separation equipment.
E431 (Polyoxyethylene (40) stearate) is used to extend the size and durability of very large soap bubbles.
E431 (Polyoxyethylene (40) stearate) is the main ingredient in many personal lubricants.
When E431 (Polyoxyethylene (40) stearate) is chemically attached to therapeutic molecules (such as protein drugs or nanoparticles), E431 (Polyoxyethylene (40) stearate) can sometimes be antigenic, stimulating an anti-E431 (Polyoxyethylene (40) stearate) antibody response in some patients.
This effect has only been shown for a few of the many available E431 (Polyoxyethylene (40) stearate)ylated therapeutics, but E431 (Polyoxyethylene (40) stearate) has significant effects on clinical outcomes of affected patients.
Other than these few instances where patients have anti-E431 (Polyoxyethylene (40) stearate) immune responses, E431 (Polyoxyethylene (40) stearate) is generally considered to be a safe component of drug formulations.
E431 (Polyoxyethylene (40) stearate) is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane.
E431 (Polyoxyethylene (40) stearate) is coupled to hydrophobic molecules to produce non-ionic surfactants.
E431 (Polyoxyethylene (40) stearate) potentially contain toxic impurities, such as ethylene oxide and 1,4-dioxane.
E431 (Polyoxyethylene (40) stearate) are nephrotoxic if applied to damaged skin.
E431 (Polyoxyethylene (40) stearate) is very sensitive to sonolytic degradation and E431 (Polyoxyethylene (40) stearate) degradation products can be toxic to mammalian cells.
E431 (Polyoxyethylene (40) stearate) is, thus, imperative to assess potential E431 (Polyoxyethylene (40) stearate) degradation to ensure that the final material does not contain undocumented contaminants that can introduce artifacts into experimental results.
Polyoxyethylene 40 stearate is soluble in ethylacetate, methanol, ethanol, and water.
E431 (Polyoxyethylene (40) stearate) is used in a study to investigate its effects on multidrug resistance (MDR) and to assess the phase behaviours of micro-emulsion to produce nanostructured drug-loaded lipid carriers.
E431 (Polyoxyethylene (40) stearate) enhances antitumor activity and modulates multidrug resistance of vinblastine sulphate, which is one of the major hurdles limiting the efficacy of cancer chemotherapy.
E431 (Polyoxyethylene (40) stearate) is a multifunctional neutral surfactant used in polishes and paper, food products, textile chemicals, household products, pharmaceutical formulations, and cosmetic formulations.
E431 (Polyoxyethylene (40) stearate) is waxy or flaky white to creamy coloured substance used as surfactant and emulsifier agent in beauty products and cosmetics.
E431 (Polyoxyethylene (40) stearate) is also known as PEG-40 stearate and polyoxyl 40 stearate.
E431 (Polyoxyethylene (40) stearate) is used on skin burn or skin irritation with anti-microbial cream or ointment.
E431 (Polyoxyethylene (40) stearate) market is growing at a significant growth over the forecast period, owing to rapid growth of emulsifiers in personal care industry.
E431 (Polyoxyethylene (40) stearate) is a non-ionic emulsifying agent.
E431 (Polyoxyethylene (40) stearate) is a synthetic polymer composed of PEG (polyethylene glycol) and stearic acid, a naturally occurring fatty acid.
Due to the presence of E431 (Polyoxyethylene (40) stearate), this ingredient may contain potentially toxic manufacturing impurities such as 1,4-dioxane.
APPLICATION:
-Pharmaceutical
-Personal Care
-Cosmetics
-Textile Chemicals
-Polishes and Paper
-Household Products
-Food
FUNCTION:
-Lubricating Agent
-Emulsifying Agent
-Additive
CLASSIFICATION:
-Nonionic surfactant: A surfactant with an uncharged hydrophilic headgroup.
-food emulsifier: A food additive used to form or maintain a uniform emulsion of two (or more) phases in a food.
-emulsifier: The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability.
APPLICATION:
-Food emulsifier:A food additive used to form or maintain a uniform emulsion of two (or more) phases in a food.
PROPERTIES:
-description: non-ionic
-Quality Level: 100
-form: powder
-application(s): detection
-InChI: 1S/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h21H,2-19H2,1H3
-InChI key: RFVNOJDQRGSOEL-UHFFFAOYSA-N
STORAGE:
Keep in sealed, unopened, original containers
SYNONYM:
E431
macrogol 40 stearate
macrogol stearate 2000
PEG stearate
polyethylene glycol monostearate
polyethylene glycol stearate
polyoxyethylene (40) monostearate
E431 (Polyoxyethylene (40) stearate)
polyoxyethylene monostearate
polyoxyethylene stearate
polyoxyl 40 stearate
polyoxyl 8 stearate
stearic acid, monoester with polyethylene glycol
