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E432 (Polysorbate 20)

CAS NUMBER:  9005-64-5

EC NUMBER: 500-019-9

E432 (Polysorbate 20) is a hydrophilic nonionic surfactant generally used as emulsifiers, dispersing agent and solubilizer.
E432 (Polysorbate 20) has been used in a study to assess its potential as a generally recognized as safe (GRAS) plasticizer in imparting plasticity to carnauba wax.

E432 (Polysorbate 20) (common commercial brand names include Scattics, Alkest TW 20 and Tween 20) is a polysorbate-type nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid. 
E432 (Polysorbate 20) stability and relative nontoxicity allows it to be used as a detergent and emulsifier in a number of domestic, scientific, and pharmacological applications. 

As the name implies the ethoxylation process leaves the molecule with 20 repeat units of polyethylene glycol; in practice these are distributed across 4 different chains, leading to a commercial product containing a range of chemical species.
E432 (Polysorbate 20) is used as a wetting agent in flavored mouth drops such as Ice Drops, helping to provide a spreading feeling to other ingredients like SD alcohol and mint flavor.

The World Health Organization has suggested acceptable daily intake limits of 0–25 mg of polyoxyethylene sorbitan esters per kg body weight.
E432 (Polysorbate 20) is used as an excipient in pharmaceutical applications to stabilize emulsions and suspensions.

E432 (Polysorbate 20) is used by philatelists to remove stamps from envelopes and to remove residues from stamps, without harming the stamp itself.
E432 (Polysorbate 20) is also used as wetting agent in rubber balers in the elastomer industry.

E432 (Polysorbate 20) has been used as a shape directing agent to synthesize spheroidal magnetite nanoassemblies.
E432 (Polysorbate 20) is an ethoxylated derivative of sorbitan monolaurate called INCI E432 (Polysorbate 20). 

E432 (Polysorbate 20) is a clear yellow to brown liquid with a freezing point of -5 °C. 
E432 (Polysorbate 20) contains 99% active ingredient. ROKwinol 20 is well soluble in water and methanol. 

E432 (Polysorbate 20) has the ability to form an O/W emulsion (oil in water).
E432 (Polysorbate 20) (Tween 20) is a surfactant and emulsifier used in cleaners and personal care products.

E432 (Polysorbate 20) is a surfactant and emulsifier used in cleaners and personal care products. 
E432 (Polysorbate 20) is an excellent solubilizer of essential oils, a wetting agent, viscosity modifier, stabilizer and dispersing agent.

E432 (Polysorbate 20) is a polysorbate type nonionic surfactant formed by ethoxylation of sorbitan prior to the addition of lauric acid. 
E432 (Polysorbate 20) stability and relative non-toxicity allow it to be used as a detergent and emulsifier in many domestic, scientific and pharmacological applications. 

E432 (Polysorbate 20) is used in the production of creams, lotions and shampoos to allow the water/oil phases to form an emulsion.
E432 (Polysorbate 20) is a nonionic surfactant and a sorbitol-derived emulsifier based on fruits and berries. 

E432 (Polysorbate 20) helps to dilute essential oils or perfume in water-based cosmetics like lotions, creams, gels.
E432 (Polysorbate 20) is produced by ethoxylation. 

The number indicates the average number of moles of ethylene oxide reacted per mole of sorbitol.
E432 (Polysorbate 20) (polyoxyethylene sorbitan monolaurate) is derived from coconut oil. 

E432 (Polysorbate 20) is a non-toxic, nonionic surfactant/emulsifier and a water-soluble yellowish liquid used as a dispersing agent which allows oil and water to mix without the use of alcohol. 
E432 (Polysorbate 20) is a fragrance solubilizer and stabilizer; it lubricates and has a soothing effect on the skin. 

This skin- safe ingredient is used extensively in oil-in-water emulsions (lotions, conditioners, cream rinses, shampoos, liquid soaps, body polishes or scrubs, etc.) and also for body mists and linen sprays.
Will be found as an ingredient in the majority of body toiletries, cosmetics and wipes now in the market. 

Polysorbates are generally used in combination with other emulsifiers such as mono- and diglycerides or sorbitan monostearates for various purposes such as to disperse flavors and colors, to make essential oils and vitamins soluble and to improve volume and texture in baked goods. 
Use E432 (Polysorbate 20) when very little foaming action (or none at all) is desired in the finished product.

E432 (Polysorbate 20) is a highly hydrophilic surfactant and approved as a food additives. 
E432 (Polysorbate 20) is a usuful emulsifier, dispersant and solubilizer for aroma chemiclas and oils.

E432 (Polysorbate 20) is a nonionic, solubilizer, o/w emulsifier, antistat and fiber lubricant used in textile industry, wetting agent, viscosity modifier, suspending agent used in food, cosmetics, drugs, textile and metal working industries, solubilizer for perfumes and flavours, insecticides, herbicides, paints and inks, pharmaceuticals.
The Polysorbates are used in a variety of products including skin fresheners, skin care products, skin cleansing products, makeup bases and foundations, shampoos, permanent waves and fragrance powders.

E432 (Polysorbate 20) is a nonionic surfactant and emulsifing agent formed by the ethoxylation of sorbitan before the addition of lauric acid, and is often used in foods and personal care products. 
E432 (Polysorbate 20) is a viscous, water-soluble yellow liquid. 

The hydrophilic groups in this compound are polyethers also known as polyoxyethylene groups which are polymers of ethylene oxide. 
In the nomenclature of polysorbates, the numeric designation following polysorbate refers to the lipophilic group, in this case the oleic acid. 

E432 (Polysorbate 20) is often used in cosmetic products as an emulsifier. 
Soluble in water & alcohols, E432 (Polysorbate 20) is insoluble in oils. 

E432 (Polysorbate 20) a fragrance solubilizer and stabilizer; it lubricates and has a soothing effect on the skin. 
This skin-safe ingredient is used extensively in oil-in-water emulsions (lotions, conditioners, cream rinses, shampoos, liquid soaps, body polishes or scrubs, etc.) and also for body mists and linen sprays. 

E432 (Polysorbate 20) functions to disperse oil in water rather than water in oil.
Polysorbates are derived from ethoxylated sorbitan (a derivative of sorbitol) esterified with fatty acids and exist as oily liquids. 

These Polysorbates belong to the class of emulsifiers used in pharmaceuticals and food preparations (salad dressing, ice cream, chocolates, baked goods and confectionery). 
They are used in cosmetics to solubilize essential oils into water-based products, pharmaceuticals, detergents, paints, and plastic applications. 

These Polysorbates surfactants consist primarily of oleic, stearic or lauric fatty acid esters with sorbitol-derived cyclic ethers (sorbitans and sorbides) and further polymerized with approximately 20 molecules of oxirane per molecule of Polysorbates.
E432 (Polysorbate 20) (commercially called Tween 20) is derived from sorbitol, a natural sugar alcohol and forms a polysorbate-type nonionic surfactant by the ethoxylation of sorbitan (derived from the dehydration of sorbitol) before the addition of lauric acid. 

E432 (Polysorbate 20) is relatively nontoxic and stable therefore can be used as a emulsifier and detergent in a number of domestic, scientific, and pharmacological applications. 
E432 (Polysorbate 20) functions as a good wetting agent having food application in flavoured mouth drops, providing a spreading feeling to other added flavour ingredients. 

E432 (Polysorbate 20) is an amber/golden-colored water-soluble viscous liquid. 
E432 (Polysorbate 20) is manufactured from polyethoxylated sorbitan (derived from the dehydration of sorbitol, a sugar alcohol) and oleic acid, a fatty acid found in vegetable fats. 

Due to this structure, polysorbate 80 forms an approximate hydrophilic-lipophilic balance of 15. 
The final products are free from genetically modified organisms and of vegetable origin. 

Polysorbate 80 (or E433) is a non-ionic surfactant and emulsifier find use in foods as emulsifier for salad dressings and chocolates, in cosmetics for preparing skin, facial cleansers and hair care products, and to disperse active ingredients in pharmaceuticals benefiting the pharmacological industry.
The solubility of Polysorbate 80 allows E432 (Polysorbate 20) to assist in dissolving ingredients that would remain solid under normal circumstances. 

In foods like ice cream, Polysorbate 80 is added up to 0.5% (v/v) concentration to make the ice cream smoother and easier to handle, as well as increasing its resistance to melting. 
Vitamins, tablets, and supplements also contain Polysorbate 80 because of its preservative nature. 

Polysorbate 80 being a nonionic surfactant is used in soaps and cosmetics (including eyedrops), or as solubilizer in mouthwashes.
In order to get the same wonderful colors you use in your other bath and body products, add Polysorbate 80 at about 2 % (of your total batch) in your liquid stage. 

This should eliminate any ring around the tub or floating mica that can occur if you don't use it. 
The full name polyoxyethylene (20) sorbitan monostearate or Polysorbate 60 or Tween 60, is an synthetic ingredient made from reaction of sorbitol, stearic acid (C18) and ethylene oxide. 

Due to this structure, polysorbate 60 forms an approximate hydrophilic-lipophilic balance of 14.9. 
The primary use of Tween 60 as an emulsifier in food (number E435) and as a solubilizer & surfactant in cosmetics is well known.

Polysorbate 60 is a synthetic multi-ingredient that can be used as a surfactant, emulsifier, solubilizer, stabilizer in food, cosmetics and personal care products. 
Polysorbate 60 helps water-based and oil-based ingredients blend easily and prevent their separation in food. 

Polysorbate 60 and 80 are mostly used in food among the category of Polysorbates, but the latter is used more than polysorbate 60 in food.
Polysorbate 60 and 80 are the most commonly used in bakery food production. 

They help to extend shelf life, improve the strength and increase volume of baked goods and frozen desserts.
As a high HLB emulsifier, its food grade can be blended with a low HLB emulsifier (e.g. sorbitan stearate, mono and diglycerides) to provide a suitable HLB value for the various food uses, either oil in water, or water in oil emulsion.

E432 (Polysorbate 20) general purpose in cosmetics is to mix water and oil together. 
Polysorbate 60 functions as a surfactant, emulsifier, solubilizer and dispersing agent. 

Some of its applications as follows: Help wash away body dirt by lowering the surface tension on the skin when used in shampoos and body washes. 
E432 (Polysorbate 20) heps distribute essential oils, fragrances and colorants evenly in water for Lotions, Creams, Hair products, Skin care products and Makeup products.

E432 (Polysorbate 20) is used as a high HLB emulsifier in combination with a variety low HLB emulsifiers to cover a wide range of oil in water, and water in oil emulsion systems. 
Alone, E432 (Polysorbate 20) is an excellent solubilizer of essential oils, a wetting agent, viscosity modifier, stabilizer and dispersing agent. 

Use E432 (Polysorbate 20) in the creation of linen and room sprays, body sprays and other products where oils need to be solubilized in water.
Used for solubilizing membrane proteins during isolation and purification.

E432 (Polysorbate 20) is used as a wetting agent in flavored mouth drops. 
E432 (Polysorbate 20) acts as a washing agent in Western blots and ELISAs and prevents antibody binding. 

E432 (Polysorbate 20) is a solubilizing agent of membrane proteins. 
In pharmaceutical chemistry, E432 (Polysorbate 20) is used as an excipient to stabilize emulsions and suspensions. 

Further, E432 (Polysorbate 20) is used as a dispersing agent, stabilizer, lubricator and also used in creams, salves, ointments, protective creams, balms, pomades, lipsticks, mascaras and glosses.
Polysorbate-20 can be used where you need water and oil to combine, room fragrances for example. 

E432 (Polysorbate 20) can also be used in shower gels, cream & skincare preparations, liquid cosmetics and shower gels or shampoos.
Polysorbates are a class of emulsifiers used in pharmaceuticals and food preparation. 

They are often used in cosmetics to solubilise essential oils and fragrance oils into water-based products. 
Polysorbate-20 is made from polyethoxylated sorbitan (chemical compounds derived from the dehydration of sugar alcohol) and oleic acid, a fatty acid found in vegetable fats.

Polysorbate-20 can be used where you need water and oil to combine, room fragrances for example. 
E432 (Polysorbate 20) can also be used in shower gels, cream & skincare preparations, liquid cosmetics and shower gels or shampoos.

Polysorbate-20 is both soothing and draws impurities from the skin making it the perfect addition to a range of skincare cleansers. 
As a guide, 10g Polysorbate-20 will solubise up to 3g of essential or fragrance oil.

E432 (Polysorbate 20) is a polysorbate-type nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid. 
E432 (Polysorbate 20) stability and relative nontoxicity allows it to be used as a detergent and emulsifier in a number of domestic, scientific, and pharmacological applications.

E432 (Polysorbate 20) is a  mild, non-ionic, vegetable derived surfactant which is fantastic for dispersing and emulsifying oil in water to assist the creation of products like linen sprays, room scenters, body and facial mists etc.  
E432 (Polysorbate 20) is the ingredient that keeps the oils suspended in water so it does not separate out

Clarity in a spray may require some adjustments as the same amount will not solubilise all scents. 
To obtain a clear product start by adding twice as much polysorbate to essential/fragrance oil and mix thoroughly. 

Slowly add distilled water to this combination. 
If the mix is cloudy you may need to add more E432 (Polysorbate 20) to the scent on your next attempt.  

5-10 times the amount of solubiliser to scent may, on occasion,  be required, so don't be too shy with it.  
Do not take the solubiliser quantitiy over 5% of your total formulation.  

The amount of E432 (Polysorbate 20) required to disperse oils will vary from product to product.
E432 (Polysorbate 20) is an emulsifying agent consisting of laurate esters of sorbitol consisting of the monoester condensed with ethylene oxide (polyoxyethylene-20 sorbitan monostearate). 

HLB Value: 16-17 (gives oil-in-water emulsions). 
Non-ionic emulsifier (enables water and oil to mix). 

Emulsifying efficacy is increased further when combined with cetyl alcohol or sorbitan stearate. 
Acts as dispersing agent and anti-static thickener. 

Very useful as solubilizer and stabilizer of essential oils.
E432 (Polysorbate 20) is a stable and non-toxic surfactant which is used as a detergent and emulsifier in a many household, cosmetic and pharmaceutical products.

E432 (Polysorbate 20) is particularly useful for dispersing essential or fragrance oils into water bases for products such as room fresheners or spritzers.
Pale yellow in colour and no scent.  

Usually used in formulations with less than 5% oils. 
E432 (Polysorbate 20) is a non-ionic surfactant commonly used as a blocking and washing agent in western blotting and other immuno-staining assays. 

E432 (Polysorbate 20) is typically included in blocking buffers and washing buffers at a concentration of 0.05-0.1% to reduce non-specific antibody binding.
E432 (Polysorbate 20) (PS20), a commonly used surfactant in biopharmaceuticals, showed degradation upon long term (~18-36 months) storage of two monoclonal antibody (mAb, mAb A and mAb B) drug products at 2-8°C.

E432 (Polysorbate 20) is naturally derived from Lauric Acid (coconut oil) and is a commonly used emulsifiers of essential oils and oil soluble fragrances. 
By mixing your essential oils or oil soluble fragrance with E432 (Polysorbate 20) before adding to your water based products it will minimize product clouding and pull the essential oil or fragrance throughout the product instead of floating on top.

E432 (Polysorbate 20) is a non-iconic emulsifier with a wide range of hydrophilic characteristics and is commonly used in "oil-in-water" emulsions as an emulsifying agent. 
E432 (Polysorbate 20) can be uses individually or in combination with other hydrophobic emulsifiers. 

E432 (Polysorbate 20), whose common commercial names includes Alkest TW 20 and E432 (Polysorbate 20), is a mild nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid which is a medium-chain fatty acid found mainly in coconut oil. 
E432 (Polysorbate 20) is allowed to be used as the emulsifier, detergent, dispersant, solvent and stabilizer, etc. in a number of fields such as pharmaceutical, chemical, food, textile and other industries due to its stability and relative non-toxicity.

E432 (Polysorbate 20) is widely applied in biological techniques and sciences, which can be added to buffers and reagents for immunohistochemistry helping to prevent non-specific antibody binding, decrease background staining and enhance reagent spreading. 
Besides, E432 (Polysorbate 20) also has applications in food production as a common food grade additive which are found in many consumables on the market today. 

E432 (Polysorbate 20) is a mixture of laurate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 mole of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides. 
Used for solubilizing membrane proteins during isolation and purification.

E432 (Polysorbate 20) is used as a wetting agent in flavored mouth drops. 
E432 (Polysorbate 20) acts as a washing agent in Western blots and ELISAs and prevents antibody binding. 

E432 (Polysorbate 20) is a solubilizing agent of membrane proteins. 
In pharmaceutical chemistry, E432 (Polysorbate 20) is used as an excipient to stabilize emulsions and suspensions. 

Further, E432 (Polysorbate 20) is used as a dispersing agent, stabilizer, lubricator and also used in creams, salves, ointments, protective creams, balms, pomades, lipsticks, mascaras and glosses.
E432 (Polysorbate 20) is a hydrophilic nonionic surfactant generally used as emulsifiers, dispersing agent and solubilizer.

The E432 (Polysorbate 20) exhibit high hydrophile-lipophile balance (HLB) values, indicating they will function to disperse oil in water as opposed to water in oil. 
HLB values for most emulsifiers fall in the range of 1.8 to 18.6, with the E432 (Polysorbate 20) in the range 9.6 to 16.7.

Because of their nonionic nature, the E432 (Polysorbate 20) are comparatively insensitive to hard water and electrolytes and may be used in both acidic and basic formulations.
The E432 (Polysorbate 20) find numerous uses in industry, research, pharmacy, and food production. 

They are used in the textile industry as antistatic agents, fiber lubricants, and finish emulsifiers. 
In biological research, they find uses in membrane protein extraction, virus deactivation, and growth culture preparation.


USES:

-hair washing, care and styling products,

-cosmetics for washing and care of the body and face,

-make-up products and make-up removers,

-preparations for hair coloring and decolorization,

-aftershave and other alcohol-based products,

-sunscreens,

-perfumes, body fragrances,

-intimate hygiene lotions and gels,

-lip care products,

-anti-acne preparations,

-air fresheners,

-nail polish and nail polish removers,

-fire resistant hydraulic fluids,

-oils and cutting fluids,

-agrochemicals.


APPLICATIONS:

-as a washing agent in immunoassays, such as Western blots and ELISAs. 

-E432 (Polysorbate 20) helps to prevent non-specific antibody binding. 

-In this major application, E432 (Polysorbate 20) is dissolved in Tris-buffered saline or phosphate buffered saline at dilutions of 0.05% to 0.5% v/v. 

-These buffers are used for washes between each immunoreaction, to remove unbound immunologicals, and eventually for incubating solutions of immunoreagents (labeled antibodies) to reduce nonspecific background.

-to saturate binding sites on surfaces (i.e., to coat polystyrene microplates, generally combined with proteins such as BSA).

-to stabilize proteins purified protein derivative (PPD) solution used in skin testing for tuberculosis exposure

-as a solubilizing agent of membrane proteins

-for lysing mammalian cells, at a concentration of 0.05% to 0.5% v/v, generally combined with other detergents, salts and additives.


ADVANTAGES:

-strong emulsifying properties,

-the active substance content in the product is at the level of 99%,

-high solubility in water and methanol,

-safe for the aquatic environment,

-biodegradable product.


PROPERTIES:

-Quality Level: 400

-grade: FG

-reg. compliance: EU Regulation 1333/2008 & 178/2002, FDA 21 CFR 172.515, FDA 21 CFR 173.310, FDA 21 CFR 175.105, FDA 21 CFR 178.3400

-description: Biological source: corn or palm

-Documentation: see Safety & Documentation for available documents

-Organoleptic: alcohol

-application(s): flavors and fragrances

-food allergen: no known allergens

-fragrance allergen: no known allergens

-InChI: 1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3


FUNCTION:

-fragrance ingredient, 

-surfactant - emulsifying agent, 

-surfactant - solubilizing agent

PHYSICAL AND CHEMICAL PROPERTIES:

-Boiling point: >100 °C

-Density: 1.1 g/cm3 (25 °C)

-Flash point: 275 °C

-Melting Point: 98.9 °C

-pH value: 6 - 8 (50 g/l, H₂O, 20 °C)

-Vapor pressure: <1.4 hPa (20 °C)

-Solubility: <0.2 mg/l soluble


STORAGE:

Store in a cool place. 
Incompatible with strong oxidizing agents.

SYNONYM:

90SOR12GHG
POLYOXYETHYLENE SORBITAN MONOSTEARATE
PEG-60 Sorbitan stearate
Polysorbate 61
Glycosperse S-20
Polyoxyethylene (20) sorbitan monostearate
Peg sorbitan stearate
PEG-3 Sorbitan stearate
PEG-6 Sorbitan stearate
UNII-CAL22UVI4M
Peg-20 sorbitan stearate
CAL22UVI4M
PEG-40 Sorbitan stearate
UNII-HD40WR33LC
Sorbimacrogol stearate 300
HD40WR33LC
UNII-X61U1UH01B
CCRIS 702
UNII-073G38N8GC
FEMA No. 2916
X61U1UH01B
Sorbitan monostearate, ethoxylated
073G38N8GC
UNII-3453J8557N

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