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E459 Beta-Cyclodextrin is a cyclic oligosaccharide produced from starch by enzymatic conversion, and E459 Beta-Cyclodextrin is used in food and beverage applications as an encapsulating agent, solubilizer, and flavor stabilizer.
E459 Beta-Cyclodextrin is valued because E459 Beta-Cyclodextrin forms inclusion complexes with many hydrophobic molecules, and this complexation helps improve solubility, reduce volatility, mask off-notes, and protect sensitive flavors or actives from oxidation.
E459 Beta-Cyclodextrin is commonly used in flavor systems, nutraceutical formulations, and functional foods, and E459 Beta-Cyclodextrin performance depends on complexation efficiency, guest molecule properties, moisture, and processing conditions.
CAS Number: 7585-39-9
EC Number: 231-493-2
Molecular Formula: C42H70O35
Molecular Weight: 1134.98 g/mol
Synonyms: E459 Beta-Cyclodextrin, Beta Cyclodextrin, β-Cyclodextrin, Beta-CD, Cyclomaltoheptaose, Schardinger Beta Dextrin (historical), Cyclic Dextrin (beta form), Starch-Derived Cyclodextrin, Beta-Cyclodextrin Encapsulant, Beta-Cyclodextrin Complexing Agent, E459, Beta-Cyclodextrin Food Additive, E459 Beta-Cyclodextrin, Beta-Cyclodextrin, β-Cyclodextrin, β-CD, BCD, Beta CD, Cyclomaltoheptaose, Cycloheptaamylose, Cycloheptaglucan, Cycloheptaose, Cycloheptaamylose Beta-Cyclodextrin, Cyclodextrin B, Cyclodextrin Beta, Beta-Dextrin, Betadex, Betadexum, Beta-Cycloamylose, Beta-Schardinger Dextrin, Schardinger Beta-Dextrin, Schardinger β-Dextrin, Cycloheptaamylose Schardinger Dextrin, Heptakis-(1,4)-Alpha-D-Glucopyranoside, Heptakis(1,4-α-D-Glucopyranoside), Heptakis-Alpha-D-Glucopyranoside, Cyclic Heptasaccharide, Cyclic Oligosaccharide Beta-Cyclodextrin, Cyclic Alpha-1,4-Glucan, Alpha-1,4-Cyclic Glucan, Cyclodextrin Food Grade, Food Grade Beta-Cyclodextrin, E459 Food Additive, E459 Encapsulating Agent, E459 Stabilizer, E459 Carrier, E459 Complexing Agent, E459 Flavor Carrier, E459 Odor Masking Agent, Beta-Cyclodextrin Encapsulant, Beta-Cyclodextrin Inclusion Complex Agent, Beta-Cyclodextrin Complexing Agent, Beta-Cyclodextrin Stabilizer, Beta-Cyclodextrin Carrier, Beta-Cyclodextrin Solubilizer, Beta-Cyclodextrin Flavor Carrier, Beta-Cyclodextrin Aroma Carrier, Beta-Cyclodextrin Odor Absorber, Beta-Cyclodextrin Taste Masking Agent, Beta-Cyclodextrin Encapsulation Agent, Pharmaceutical Beta-Cyclodextrin, Pharma Grade Beta-Cyclodextrin, Cosmetic Grade Beta-Cyclodextrin, Industrial Beta-Cyclodextrin
APPLICATIONS
E459 Beta-Cyclodextrin is used in flavor encapsulation to reduce volatility and protect aroma compounds during processing and storage.
E459 Beta-Cyclodextrin is incorporated into powdered flavor systems to improve stability and reduce flavor loss during drying.
E459 Beta-Cyclodextrin is used in beverage flavor preparations to stabilize sensitive citrus, mint, and spice notes in compatible systems.
E459 Beta-Cyclodextrin is used to mask undesirable odors and tastes by binding hydrophobic off-notes and reducing their perception.
E459 Beta-Cyclodextrin is incorporated into functional beverages to reduce bitterness or unpleasant aroma from botanical extracts in compatible formulations.
E459 Beta-Cyclodextrin is used in fortified products to improve palatability of certain vitamins and nutraceutical ingredients.
E459 Beta-Cyclodextrin is used to improve solubility and dispersibility of hydrophobic compounds in aqueous systems.
E459 Beta-Cyclodextrin is incorporated into beverage concentrates to help solubilize flavor oils and reduce separation.
E459 Beta-Cyclodextrin is used in clear drinks in selected applications to support stable delivery of hydrophobic actives.
E459 Beta-Cyclodextrin is used in chewing gum and confectionery to protect flavors and provide longer-lasting flavor release.
E459 Beta-Cyclodextrin is incorporated into mints and candies to stabilize volatile flavors and improve shelf life aroma retention.
E459 Beta-Cyclodextrin is used in chocolate and fat-based confectionery to reduce oxidation of sensitive flavor components in compatible designs.
E459 Beta-Cyclodextrin is used in bakery products to protect flavors during baking and improve aroma stability in finished goods.
E459 Beta-Cyclodextrin is incorporated into cake and biscuit flavor systems to reduce flavor loss during thermal processing.
E459 Beta-Cyclodextrin is used in baking mixes to stabilize flavor powders and improve storage stability.
E459 Beta-Cyclodextrin is used in dairy products to stabilize flavors and reduce off-notes in compatible formulations.
E459 Beta-Cyclodextrin is incorporated into yogurt and dairy desserts to improve flavor retention and aroma stability.
E459 Beta-Cyclodextrin is used in coffee and cocoa-based drinks to reduce harsh notes and stabilize aroma compounds.
E459 Beta-Cyclodextrin is used in nutraceuticals and dietary supplements to improve stability and handling of sensitive actives.
E459 Beta-Cyclodextrin is incorporated into tablet and capsule formulations to support uniform distribution of hydrophobic actives.
E459 Beta-Cyclodextrin is used in powdered supplement mixes to improve flow and reduce active ingredient degradation.
E459 Beta-Cyclodextrin is valued because E459 Beta-Cyclodextrin provides a versatile complexation platform that improves flavor stability, masks off-notes, and enhances solubility of hydrophobic components in many food systems.
E459 Beta-cyclodextrin is used in food flavors to encapsulate aroma compounds and improve stability.
E459 Beta-cyclodextrin supports protection of volatile flavors from oxidation and evaporation.
E459 Beta-cyclodextrin helps improve shelf life of flavor systems in dry mixes.
E459 Beta-cyclodextrin is used in powdered beverages to stabilize flavor and reduce aroma loss.
E459 Beta-cyclodextrin supports controlled release of flavor during reconstitution.
E459 Beta-cyclodextrin helps reduce off-odor development in stored powders.
E459 Beta-cyclodextrin is used in instant coffee and coffee aroma systems to retain volatile notes.
E459 Beta-cyclodextrin supports encapsulation of key coffee volatiles.
E459 Beta-cyclodextrin helps improve aroma impact after brewing or reconstitution.
E459 Beta-cyclodextrin is used in tea and herbal extract powders to stabilize aroma and taste compounds.
E459 Beta-cyclodextrin supports masking of bitter or astringent notes in some extracts.
E459 Beta-cyclodextrin helps improve sensory acceptance of botanical powders.
E459 Beta-cyclodextrin is used in functional beverages to improve solubility of certain hydrophobic ingredients.
E459 Beta-cyclodextrin supports inclusion complexes with lipophilic actives.
E459 Beta-cyclodextrin helps improve clarity and stability in some beverage systems.
E459 Beta-cyclodextrin is used in vitamin and nutraceutical formulations to improve dispersibility of fat-soluble components.
E459 Beta-cyclodextrin supports delivery of certain lipophilic vitamins in aqueous matrices.
E459 Beta-cyclodextrin helps reduce precipitation and separation in some supplement drinks.
E459 Beta-cyclodextrin is used in chewing gum to retain flavors and provide longer-lasting flavor release.
E459 Beta-cyclodextrin supports controlled release of encapsulated flavor oils during chewing.
E459 Beta-cyclodextrin helps reduce flavor loss during gum manufacturing.
E459 Beta-cyclodextrin is used in confectionery to protect sensitive flavors from heat during processing.
E459 Beta-cyclodextrin supports encapsulation of flavor compounds before cooking steps.
E459 Beta-cyclodextrin helps improve flavor intensity in finished candies.
E459 Beta-cyclodextrin is used in bakery flavors to protect aromas through baking and storage.
E459 Beta-cyclodextrin supports reduced volatilization of aroma compounds during heating.
E459 Beta-cyclodextrin helps improve flavor retention in baked goods.
E459 Beta-cyclodextrin is used in spices and seasoning blends to stabilize volatile aroma components.
E459 Beta-cyclodextrin supports reduced aroma loss during storage of dry seasonings.
E459 Beta-cyclodextrin helps improve sensory consistency of seasoning products.
E459 Beta-cyclodextrin is used to mask undesirable odors in food ingredients in some applications.
E459 Beta-cyclodextrin supports binding of certain odor molecules in inclusion complexes.
E459 Beta-cyclodextrin helps improve acceptance of strongly flavored functional ingredients.
E459 Beta-cyclodextrin is used in edible oil flavor systems to stabilize certain aroma compounds.
E459 Beta-cyclodextrin supports protection of oxidation-sensitive flavor notes.
E459 Beta-cyclodextrin helps reduce off-flavor formation in stored flavored oils in some designs.
E459 Beta-cyclodextrin is used in food packaging research as an active component for aroma retention or odor control in some designs.
E459 Beta-cyclodextrin supports controlled release or capture of volatile compounds in packaging systems.
E459 Beta-cyclodextrin helps improve freshness perception in stored foods in some concepts.
E459 Beta-cyclodextrin is used in pharmaceuticals to improve solubility of poorly soluble drugs.
E459 Beta-cyclodextrin supports inclusion complex formation with hydrophobic active ingredients.
E459 Beta-cyclodextrin helps increase dissolution rate and bioavailability of some APIs.
E459 Beta-cyclodextrin is used in oral solid dosage forms to improve stability of sensitive APIs.
E459 Beta-cyclodextrin supports protection of drugs from moisture and oxidation in some systems.
E459 Beta-cyclodextrin helps reduce degradation during storage.
E459 Beta-cyclodextrin is used in liquid formulations to solubilize lipophilic actives in some products.
E459 Beta-cyclodextrin supports clearer solutions or stable suspensions depending on API properties.
E459 Beta-cyclodextrin helps improve dosing consistency in liquid medicines.
E459 Beta-cyclodextrin is used in taste masking for bitter drugs in some formulations.
E459 Beta-cyclodextrin supports complexation that reduces interaction of bitter molecules with taste receptors.
E459 Beta-cyclodextrin helps improve patient compliance in oral medicines.
E459 Beta-cyclodextrin is used in nasal and ocular formulations in some markets to enhance solubility and tolerability.
E459 Beta-cyclodextrin supports stabilization of actives in aqueous solutions.
E459 Beta-cyclodextrin helps improve comfort by reducing irritation from poorly soluble actives in some systems.
E459 Beta-cyclodextrin is used in topical formulations to reduce odor and improve stability of certain actives.
E459 Beta-cyclodextrin supports controlled release of fragrances or actives in creams.
E459 Beta-cyclodextrin helps improve sensory profile of topical products.
E459 Beta-cyclodextrin is used in personal care products to encapsulate fragrances for longer-lasting scent.
E459 Beta-cyclodextrin supports controlled fragrance release over time.
E459 Beta-cyclodextrin helps improve fragrance stability in deodorants and body sprays in some systems.
E459 Beta-cyclodextrin is used in deodorant formulations to capture malodor molecules.
E459 Beta-cyclodextrin supports binding of odor-causing volatiles.
E459 Beta-cyclodextrin helps reduce malodor perception without heavy masking perfumes.
E459 Beta-cyclodextrin is used in laundry products to trap odors and improve fragrance performance in some formulations.
E459 Beta-cyclodextrin supports odor capture during wear and storage.
E459 Beta-cyclodextrin helps improve long-lasting freshness perception.
E459 Beta-cyclodextrin is used in fabric refresh sprays to capture odor molecules.
E459 Beta-cyclodextrin supports reduction of smoke and cooking odors in textiles.
E459 Beta-cyclodextrin helps improve room and fabric deodorization performance.
E459 Beta-cyclodextrin is used in household air fresheners for controlled fragrance release in some products.
E459 Beta-cyclodextrin supports stabilization of fragrance composition.
E459 Beta-cyclodextrin helps reduce rapid fragrance loss after spraying.
E459 Beta-cyclodextrin is used in cosmetics to improve stability of volatile or oxidation-sensitive ingredients.
E459 Beta-cyclodextrin supports encapsulation of certain actives and fragrances.
E459 Beta-cyclodextrin helps reduce irritation by controlling release in some systems.
E459 Beta-cyclodextrin is used in hair care to encapsulate fragrances and reduce malodor in some products.
E459 Beta-cyclodextrin supports long-lasting freshness in hair products.
E459 Beta-cyclodextrin helps improve sensory profile of shampoos and sprays.
E459 Beta-cyclodextrin is used in agrochemical formulations to improve solubility and stability of some actives.
E459 Beta-cyclodextrin supports controlled release and reduced volatility of certain pesticides.
E459 Beta-cyclodextrin helps improve handling and performance in some spray systems.
E459 Beta-cyclodextrin is used in environmental remediation research to bind hydrophobic pollutants.
E459 Beta-cyclodextrin supports complexation of organic contaminants in water.
E459 Beta-cyclodextrin helps improve removal of certain pollutants in treatment approaches.
E459 Beta-cyclodextrin is used in analytical chemistry to improve separation of hydrophobic analytes in some methods.
E459 Beta-cyclodextrin supports inclusion interactions that change retention behavior.
E459 Beta-cyclodextrin helps improve selectivity in chromatographic separations.
E459 Beta-cyclodextrin is used in chiral separations as a selector in some chromatography and capillary electrophoresis methods.
E459 Beta-cyclodextrin supports differentiation of enantiomers via inclusion complexes.
E459 Beta-cyclodextrin helps improve resolution of chiral compounds in analytical labs.
E459 Beta-cyclodextrin is used in product development to improve stability of flavors, fragrances, and actives through encapsulation.
E459 Beta-cyclodextrin supports screening of inclusion complexes for targeted release profiles.
E459 Beta-cyclodextrin helps optimize sensory and stability outcomes in formulated products.
E459 Beta-cyclodextrin is used in manufacturing troubleshooting to reduce odor issues and improve fragrance longevity.
E459 Beta-cyclodextrin supports odor capture and controlled fragrance release in consumer products.
E459 Beta-cyclodextrin helps stabilize volatile ingredients during storage and transport.
DESCRIPTION
E459 Beta-Cyclodextrin is a ring-shaped carbohydrate composed of seven glucose units linked in a cyclic structure, and the interior of E459 Beta-Cyclodextrin is relatively hydrophobic while the exterior is hydrophilic.
E459 Beta-Cyclodextrin forms inclusion complexes by trapping suitable hydrophobic molecules inside its cavity, and this complexation can reduce volatility, improve oxidative stability, and modify sensory perception.
E459 Beta-Cyclodextrin is produced from starch using cyclodextrin glycosyltransferase enzymes, followed by purification to food-grade specifications.
E459 Beta-Cyclodextrin can reduce bitterness and off-odors by binding odor-active compounds, but performance depends strongly on molecule size, polarity, and formulation conditions.
E459 Beta-Cyclodextrin can improve handling of volatile flavors in dry mixes, and E459 Beta-Cyclodextrin can support controlled release when the complex dissociates during consumption.
E459 Beta-Cyclodextrin should be used according to applicable food additive regulations and good manufacturing practices for the target market.
E459 Beta-Cyclodextrin is typically supplied as a white crystalline powder, and proper dispersion is needed to avoid lumping during hydration.
E459 Beta-Cyclodextrin has limited water solubility compared with some modified cyclodextrins, so formulation design must consider solubility limits and complexation approach.
E459 Beta-Cyclodextrin should be stored in tightly closed containers in a cool, dry place to prevent moisture pickup and maintain consistent complexation performance.
E459 Beta-cyclodextrin is a cyclic oligosaccharide composed of seven glucose units arranged in a ring structure.
E459 Beta-cyclodextrin has a hydrophilic exterior and a relatively hydrophobic внутрен cavity that can host small molecules.
E459 Beta-cyclodextrin forms inclusion complexes with many hydrophobic compounds, which can improve solubility and stability.
E459 Beta-cyclodextrin is used in foods to encapsulate flavors and reduce odors, and it is used in pharmaceuticals to enhance drug solubility.
E459 Beta-cyclodextrin can enable controlled release of encapsulated molecules based on humidity, temperature, and matrix interactions.
E459 Beta-cyclodextrin performance depends on guest molecule size, complexation ratio, processing method, and moisture conditions.
E459 Beta-cyclodextrin is typically supplied as a white crystalline powder with low sweetness and good handling properties.
E459 Beta-cyclodextrin should be stored in tightly closed containers in a cool, dry place to prevent moisture pickup and preserve performance.
E459 Beta-cyclodextrin is valued for versatile encapsulation, odor control, and broad usefulness across food, pharma, and personal care applications.
PROPERTIES
Chemical Formula: C42H70O35
Molecular Weight: 1134.98 g/mol
Common Name: E459 Beta-Cyclodextrin
Chemical Type: Cyclic oligosaccharide; encapsulating agent; complexing agent; solubilizer
Appearance: White crystalline powder
Odor: Odorless
Taste: Mild, slightly sweet
Solubility: Slightly soluble in water; more soluble in warm water; solubility is formulation dependent
Complexation: Forms inclusion complexes with suitable hydrophobic molecules
Stability: Stable under normal storage; sensitive to high humidity due to moisture uptake
Hygroscopicity: Low to moderate; depends on storage conditions
Thermal Stability: Stable under typical food processing; performance depends on guest molecule stability
Storage Temperature: 15–30°C, tightly closed, dry
Shelf Life: Typically 24–48 months in original sealed packaging (supplier dependent)
FIRST AID
Inhalation:
Move to fresh air if dust is inhaled.
Seek medical attention if respiratory irritation persists.
Avoid breathing dust during powder handling.
Skin Contact:
Wash with soap and water after contact.
Remove contaminated clothing and wash before reuse.
Seek medical advice if irritation develops or persists.
Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation persists.
Ingestion:
Rinse mouth with water.
Seek medical attention if discomfort occurs.
Never give anything by mouth to an unconscious person.
Note to Physicians:
Treat symptomatically.
No specific antidote is required.
Provide supportive care as needed.
HANDLING AND STORAGE
Handling:
Use appropriate PPE including gloves and safety glasses for bulk handling.
Avoid generating dust and avoid inhalation of fine powder.
Add slowly under agitation during hydration to reduce lumping and dusting.
Ventilation:
Use general ventilation for normal handling.
Use local exhaust where dust may be generated during powder transfer.
Minimize airborne particulate accumulation in enclosed areas.
Storage:
Store in tightly closed containers in a cool, dry place.
Protect from moisture to prevent caking and maintain consistent performance.
Keep away from strong odors and volatile chemicals because E459 Beta-Cyclodextrin can complex some odor-active compounds.
Spill and Leak Procedures:
Sweep up spilled powder and avoid dust generation.
Collect into suitable containers for reuse or disposal according to local regulations.
Clean residues with water if needed and dry the area to prevent slip hazards.
Handling Precautions:
Design complexation based on the target guest molecule because E459 Beta-Cyclodextrin performance depends on size fit, polarity, and processing conditions.
Control moisture because humidity can affect powder flow and complex stability in storage.
Rotate stock using FIFO practices to maintain consistent quality and predictable encapsulation performance.
