Quick Search

PRODUCTS

E579 (FERROUS GLUCONATE)

CAS Number: 299-29-6
Formula: C12 H24 Fe O14
Molecular Weight :482.17
Boiling Point : 673.60 °C. @ 760.00 mm Hg 
Flash Point : 707.00°F ( 375.20 °C ) 

E579 (Ferrous gluconate) is a type of iron. You normally get iron from the foods you eat. 
In your body, iron becomes a part of your hemoglobin and myoglobin. 
Hemoglobin carries oxygen through your blood to tissues and organs. Myoglobin helps your muscle cells store oxygen.
E579 (Ferrous gluconate) is used to treat or prevent iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body).

E579 (Ferrous gluconate) may also be used for purposes not listed in this medication guide.
E579 (Ferrous gluconate) is a form of mineral iron for oral administration.
E579 (Ferrous gluconate) is absorbed in the stomach and small intestine and combines with apoferritin to form ferritin, which is stored in the liver, spleen, red bone marrow, and intestinal mucosa. 
Important in transport of oxygen by hemoglobin to the tissues, iron is also found in myoglobin, transferrin, and ferritin, and is as a component of many enzymes such as catalase, peroxidase, and cytochromes.

E579 (Ferrous gluconate) is yellow-gray or light yellow-green crystal particles or powder, with a slight caramel smell.  
Soluble in water, 5% aqueous solution is acidic, almost insoluble in ethanol, the theoretical iron content is 12%. 
E579 (Ferrous gluconate) is easy to absorb, has no irritation to the digestive system, no side effects, and has no effect on the sensory properties and flavor of the food. 
E579 (Ferrous gluconate) can also be used as a drug to treat anemia.

E579 (Ferrous gluconate) can be used as a color-protecting agent and nutrient enhancer in food. 
E579 (Ferrous gluconate) can be formed by neutralizing gluconate with reduced iron. 
The characteristics of E579 (Ferrous gluconate) are high bioavailability, good solubility in water, mild flavor without astringency, and more fortification in milk drinks.
E579 (Ferrous gluconate) is also easy to cause changes in food color and flavor, which limits its application to a certain extent.

E579 (Ferrous gluconate) have Pale greenish-yellow to yellowish-grey powder or granules, which may have a faint odour of burnt sugar.
The color of E579 (Ferrous gluconate)/solution depends on pH; they are light yellow at pH 2, brown at pH 4.5, and green at pH 7. 
The iron rapidly oxidizes at higher pH.
The melting point for D-gluconic acid, ferrous salt dihydrate (98%) is 188 °C, decomposes. 

E579 (Ferrous gluconate) is a salt of the gluconic acid which represents a compound of iron and two molecules of gluconic acid. 
E579 (Ferrous gluconate) is a yellow-green crystalline powder, with the characteristic odor similar to burnt sugar.
In the crystalline state E579 (Ferrous gluconate) is stable in the air, while its aqueous solution is sensitive to light. 

The solubility of E579 (Ferrous gluconate) in water is 8.5 g in 100 cm3 of water at 20 °C. 
E579 (Ferrous gluconate) is poorly soluble in ethanol, and insoluble in ether. 
E579 (Ferrous gluconate) based preparations contain iron in the ferrous form, and their intake is recommended in the state of iron-deficiency anemia and bleeding.

The specific optical rotation is +6.7 deg at 25 °C (c=1, H2O). 
E579 (Ferrous gluconate) is soluble with slight heating in water. 
E579 (Ferrous gluconate) is practically insoluble in ethanol

E579 (Ferrous gluconate) is soluble in glycerin
1 gramE579 (Ferrous gluconate) dissolves in about 10 ml of water with slight heating and in 1.3 ml of water at 100 °C.
E579 (Ferrous gluconate) forms supersaturated solutions which are stable for a period of time.

Molecular formula ofE579 (Ferrous gluconate): C12H22FeO14•2H2O
Molecular weight ofE579 (Ferrous gluconate):482
IUPAC Name ofE579 (Ferrous gluconate): iron(2+);(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate;dihydrate
Traits ofE579 (Ferrous gluconate): yellow gray or light green fine powder or granules.
Quality indicators ofE579 (Ferrous gluconate):E579 (Ferrous gluconate) also meets the requirements of the Chinese, British and American Pharmacopoeias.
Uses ofE579 (Ferrous gluconate): nutritional supplements, iron calcium fortifiers, pigment additives.

Content ofE579 (Ferrous gluconate): 
(dry basis)%: ≥95
Hydrogen Bond Donor Count:12    
Hydrogen Bond Acceptor Count:16    
Rotatable Bond Count:8    

Exact Mass:482.057020    
Monoisotopic Mass:482.057020    
Topological Polar Surface Area:285 Ų    
Heavy Atom Count:29    

Formal Charge:0    
Complexity:165    
Isotope Atom Count:0    

Defined Atom Stereocenter Count:8    
Undefined Atom Stereocenter Count:0    
Defined Bond Stereocenter Count:0    

Undefined Bond Stereocenter Count:0    
Covalently-Bonded Unit Count:5    
Compound Is Canonicalized:Yes

E579 (Ferrous gluconate) is an iron mineral salt used in iron and multivitamin supplements.
“Ferrous” means “iron,” a mineral critical to the transportation of oxygen by red blood cells to the body's tissues. 
Iron deficiency will result in a shortage of red blood cells (anemia), a potentially life-threatening condition. 

E579 (Ferrous gluconate) is a black dye.
E579 (Ferrous gluconate) is composed of iron, bound to two molecules of gluconic acid, which is the acid form of glucose.
E579 (Ferrous gluconate) is the black dye used to color ripe olives.
E579 (Ferrous gluconate)is also used as am iron supplement to cure iron deficiency anemia.

E579 (Ferrous gluconate) can be used as a dietary ingredient and as a nutrient. 
This product is known to be used for pharmaceutical applications. 
Iron has a vital function in combining with protein and copper to make hemoglobin.
Iron also prevents fatigue and promotes good skin tone. 

Why is it important for my child to take E579 (Ferrous gluconate)?
Anaemia is a blood condition where there is a lack of a protein called haemoglobin. 
Haemoglobin is needed to carry oxygen in the blood and transport it around the body. 
Children with anaemia are often pale, feel tired, have little energy, and may not grow or develop properly.

E579 (Ferrous gluconate) is a form of iron that can be taken by mouth. 
E579 (Ferrous gluconate) helps the body to make more haemoglobin and so treat the anaemia. 
E579 (Ferrous gluconate) can also be used to prevent anaemia in children who are at risk of it or, for example, before surgery.

Iron(II) Gluconate (E579 (Ferrous gluconate)) is generally immediately available in most volumes. 
High purity, submicron and nanopowder forms may be considered. 
American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards. 
E579 (Ferrous gluconate) has a typical and custom packaging. 

E579 (Ferrous gluconate) is a yellowish gray or pale greenish yellow powder or granules C12H22FeO14 used as a hematinic in the treatment of iron-deficiency anemia.
How should I store E579 (Ferrous gluconate)?
-Keep in a cool, dry place, away from direct sunlight
-Store at room temperature
-Keep the container tightly closed. 
-Store in the original container.

E579 (Ferrous gluconate)s are used for the treatment and prevention of iron deficiency.
E579 (Ferrous gluconate) is a form of iron. 
Iron is necessary for the production of haemoglobin (protein in red blood cells), which carries oxygen around the body. 
Iron is involved in the formation of myoglobin, a pigment that stores oxygen in muscles for use during exercise.

E579 (Ferrous gluconate) with food and drink 
If you drink large amounts of tea, coffee or milk or milk products, or eat eggs and whole grain breads and cereals at the same time as taking E579 (Ferrous gluconate), your body may absorb less of the iron contained in the tablets which can reduce the effects of E579 (Ferrous gluconate). 

Dietary supplement, food colour for ripe olives Iron(II) gluconate, or E579 (Ferrous gluconate), is a black compound often used as an iron supplement. 
E579 (Ferrous gluconate)is the iron(II) salt of gluconic acid. 
E579 (Ferrous gluconate) is marketed under brand names such as Fergon, Ferralet, and Simron. 
E579 (Ferrous gluconate)is also present in the combination supplement dianazene, a vitamin mixture created by L. Ron Hubbard and used in the religion Scientology.

Water Solubility of E579 (Ferrous gluconate):36.6 g/L    
logP of E579 (Ferrous gluconate):-2    
logS of E579 (Ferrous gluconate):-1.1    

pKa of E579 (Ferrous gluconate) (Strongest Acidic):3.39    
pKa of E579 (Ferrous gluconate) (Strongest Basic)    :-3    
Physiological Charge of E579 (Ferrous gluconate):-1    

Hydrogen Acceptor Count of E579 (Ferrous gluconate):7    
Hydrogen Donor Count of E579 (Ferrous gluconate):5    
Polar Surface Area of E579 (Ferrous gluconate):41.28 Ų    
Rotatable Bond Count of E579 (Ferrous gluconate):10    

Refractivity of E579 (Ferrous gluconate):49.11 m³·mol⁻¹    
Polarizability of E579 (Ferrous gluconate):16.5 ų    
Number of Rings:0    
Bioavailability of E579 (Ferrous gluconate):Yes    

Rule of Five:Yes    
Ghose Filter:No    
Veber's Rule:No    
MDDR-like Rule:No

Chemical Formula of E579 (Ferrous gluconate):C12H22FeO14
IUPAC name of E579 (Ferrous gluconate):λ²-iron(2+) ion bis(2,3,4,5,6pentahydroxyhexanoate)
Mass Composition of E579 (Ferrous gluconate): C 32.31%; H 4.97%; Fe 12.52%; O 50.21%

E579 (Ferrous gluconate) delivers iron in each tablet. 
Every cell in the human body contains iron, with the majority of the body's iron found in red blood cells that carry oxygen from the lungs to the rest of the body. 
Preservative and gluten free. 
No sugar, starch, artificial flavors, wheat, yeast or corn added.
Take E579 (Ferrous gluconate) on an empty stomach, at least 1 hour before or 2 hours after a meal.

E579 (Ferrous gluconate) is used in the treatment of:
-Pregnancy Complications, Hematologic
-E579 (Ferrous gluconate) is used in the prevention of:
-Anemia, Iron-Deficiency

E579 (Ferrous gluconate) or iron (II) gluconate, with iron in the +2 oxidation state, can be used as an iron supplement in food, a color additive for ripe olives, also for the treatment of iron deficiency anemia in medical uses. 
The European food additive number for E579 (Ferrous gluconate) is E579.

How is E579 (Ferrous gluconate) made?
E579 (Ferrous gluconate) can be produced by the reaction of calcium gluconate, sulfuric acid, sodium carbonate and ferrous sulfate. 

And the following are the brief manufacturing process:
Obtain a gluconic acid solution: sulfuric acid reacts with calcium gluconate.
Obtain ferrous carbonate: the reaction between sodium carbonate and ferrous sulfate. 
Gluconic acid solution reacts with excess ferrous carbonate.
E579 (Ferrous gluconate) can also be made from directly reacting gluconic acid (obtained from calcium gluconate) with iron powder.

The uses of E579 (Ferrous gluconate) in food including as a nutrient supplement, such as in vitamins and minerals supplement, also in infant formula.
E579 (Ferrous gluconate) also can be used as a food coloring, making ripe olives black. 

Pharmaceutical Uses Of E579 (Ferrous gluconate) 
E579 (Ferrous gluconate) is used for treating or preventing iron deficiency anemia.
Besides E579 (Ferrous gluconate)s pure form (powder or granular) sold as a bulk ingredient in the market, you can commonly find the tablet formulation of E579 (Ferrous gluconate) as an iron supplement with various dosages available in B2C market, for example, 324 mg, 325 mg, 300mg, 240 mg, 225 mg and so on.
Iron quantities in them are around 38mg, 38mg, 35mg, 26mg, 28mg, respectively. Iron quantities are calculated by [the quantity of E579 (Ferrous gluconate)] multiply [the molecular weight of iron]divide [the molecular weight of E579 (Ferrous gluconate)].
E579 (Ferrous gluconate) can also be added in the production of multivitamin capsules and syrups.
Another two iron(II) salts, ferrous sulfate and ferrous fumarate can also be used to treat anemia. 

Is E579 (Ferrous gluconate) Safe to Eat?
Yes, it has been approved safe by the U.S. Food and Drug Administration (FDA) and European Food Safety Authority (EFSA), as well as the Joint FAO/WHO Expert Committee on Food Additives (JECFA).

FDA
Nutrient supplement: E579 (Ferrous gluconate) is generally recognized as safe (GRAS) when used as a nutrient supplement in food with no limitation other than current good manufacturing practice. 
Also, E579 (Ferrous gluconate) may be used in infant formula.
Color additive: E579 (Ferrous gluconate) may be safely used for the coloring of ripe olives.
Feed additive: E579 (Ferrous gluconate) is also GRAS when used as nutrients and/or dietary supplements in animal drugs, feeds, and related products.

E579 (Ferrous gluconate) it vegan?
Yes, E579 (Ferrous gluconate) is vegan as the raw material, calcium gluconate, sulfuric acid, sodium carbonate and ferrous sulfate are derived from the chemical synthesize, without the use of animal matter or products derived from animal origin. 
So E579 (Ferrous gluconate) is suitable for vegetarians.

Is E579 (Ferrous gluconate) the same with ferric gluconate?
No, different with ferric gluconate, the iron in which present +3 oxidation state, Fe3+. 

Is E579 (Ferrous gluconate) gluten free?
Yes, it is gluten free as it does not contain wheat, rye, barley, or crossbreeds of these grains, therefore can be used for people with celiac disease.

Synonyms:
-biofergate
-ferrin 55
-ferroglyconicum
-gluconic acid iron salt
-iron (II) di-D-gluconate
-iron digluconate
-iron gluconate
-iron, bis(D-gluconato-O1,O2)-
-iron; (2R,3R,4S,5S)-2,3,4,5,6-pentahydroxyhexanoic acid
-iron(II) di-D-gluconate
-sodium ferric gluconate complex
-E579 (Ferrous gluconate)
-ferroglyconicum
-glucoferron

  • Share !
E-NEWSLETTER